Molecular and Cellular Biology
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MOLECULAR AND CELLULAR BIOLOGY Volume 5 December 1985 No. 12 Effect of Double-Strand Breaks on Homologous Recombination in Mammalian Cells and Extracts. Kyu-Young Song, Lavanya Chekuri, Sikha Rauth, Stacy Ehrlich, and Raju Kucherlapati................................ 3331-3336 Nucleotide Sequence and Expression In Vitro of cDNA Derived from mRNA of int-1, a Provirally Activated Mouse Mammary Oncogene. Y.-K. T. Fung, G. M. Shackleford, A. M. C. Brown, G. S. Sanders, and H. E. Varmus 3337-3344 Augmented Expression of Normal c-myc Is Sufficient for Cotransformation of Rat Embryo Cells with a Mutant ras Gene. William M. F. Lee, Manfred Schwab, David Westaway, and Harold E. Varmus ...................... 3345-3356 Diphtheria Toxin-Resistant Mutants of Saccharomyces cerevisiae. Jeou-Yuan C. Chen, James W. Bodley, and Dennis M. Livingston.................... 3357-3360 Recombinant Interleukin 2 Regulates Levels of c-myc mRNA in a Cloned Murine T Lymphocyte. John C. Reed, Daniel E. Sabath, Richard G. Hoover, and Michael B. Prystowsky............................................. 3361-3368 A Murine Recombinant Retrovirus Containing the src Oncogene Transforms Erythroid Precursor Cells In Vitro. Steven M. Anderson, S. Peter Klinken, and W. David Hankins ...................................... 3369-3375 Pichia pastoris as a Host System for Transformations. James M. Cregg, Kevin J. Barringer, Anita Y. Hessler, and Knut R. Madden.................... 3376-3385 Members of the src and ras Oncogene Families Supplant the Epidermal Growth Factor Requirement of BALB/MK-2 Keratinocytes and Induce Distinct Alter- ations in Their Terminal Differentiation Program. Bernard Weissman and Stuart A. Aaronson .................................................. 3386-3396 A Deletion of the 3' End of the Drosophila melanogaster hsp7O Gene Increases Sta- bility of Mutant mRNA During Recovery from Heat Shock. Amanda A. Simcox, Clarissa M. Cheney, Eric P. Hoffman, and Allen Shearn......... 3397-3402 Vaccinia Virus Expression Vector: Coexpression of I8-Galactosidase Provides Vi- sual Screening of Recombinant Virus Plaques. Sekhar Chakrabarti, Kathleen Brechling, and Bernard Moss ................................ 3403-3409 Cloning and Molecular Analysis of the HAP2 Locus: a Global Regulator of Respi- ratory Genes in Saccharomyces cerevisiae. Jennifer L. Pinkham and Leonard Guarente ................................................... 3410-3416 Genes for Low-Molecular-Weight Heat Shock Proteins of Soybeans: Sequence Analysis of a Multigene Family. Ronald T. Nagao, Ewa Czarnecka, William B. Gurley, Fritz Schoffl, and Joe L. Key ....................... 3417-3428 Effect of RPSI Gene Dosage Alterations on Ribosome Synthesis in Saccharomyces cerevisiae. Nadja Abovich, Linda Gritz, Lin Tung, and Michael Rosbash ... 3429-3435 Posttranscriptional Regulation and Assembly into Ribosomes of a Saccharomyces cerevisiae Ribosomal Protein- -Galactosidase Fusion. Linda Gritz, Nadja Abovich, John L. Teem, and Michael Rosbash ......................... 3436-3442 DNA Precursor Pools and Ribonucleotide Reductase Activity: Distribution be- tween the Nucleus and Cytoplasm of Mammalian Cells. Janet M. Leeds, Mary B. Slabaugh, and Christopher K. Mathews....................... 3443-3450 Deletions Extending from a Single Tyl Element in Saccharomyces cerevisiae. Karen M. Downs, Gina Brennan, and Susan W. Liebman................ 3451-3457 Continuted on following page Continued from preceding page Characterization of the Human c-fms Gene Product and Its Expression in Cells of the Monocyte-Macrophage Lineage. Joseph Woolford, Victoria Rothwell, and Larry Rohrschneider ............................................. 3458-3466 Transformation by the v-fms Oncogene Product: Role of Glycosylational Process- ing and Cell Surface Expression. E. J. Nichols, R. Manger, S. Hakomori, A. Herscovics, and L. R. Rohrschneider ............................... 3467-3475 Constitutively Expressed Rat mRNA Encoding a 70-Kilodalton Heat-Shock-Like Protein. Karen O'Malley, Alex Mauron, Jack D. Barchas, and Larry Kedes .............................................................. 3476-3483 Extrachromosomal DNA Transformation of Caenorhabditis elegans. Dan T. Stinchcomb, Jocelyn E. Shaw, Stephen H. Carr, and David Hirsh ..... ... 3484-3496 Genetic Engineering in the Precambrian: Structure of the Chicken Triosephos- phate Isomerase Gene. Donald Straus and Walter Gilbert ..... .......... 3497-3506 Enhancer-Dependent Expression of the Rat Preproinsulin Gene in Bovine Papillo- mavirus Type 1 Vectors. Nava Sarver, Ruth Muschel, Janet C. Byrne, George Khoury, and Peter M. Howley ................................. 3507-3516 Mutations in Cognate Genes of Saccharomyces cerevisiae hsp7O Result in Reduced Growth Rates at Low Temperatures. Elizabeth A. Craig and Kurt Jacobsen ............................................................ 3517-3524 Coordinate Expression of Amplified Metallothionein I and II Genes in Cadmium- Resistant Chinese Hamster Cells. Jeffrey K. Griffith ...... .............. 3525-3531 Meiotic Exchange within and between Chromosomes Requires a Common Rec Function in Saccharomyces cerevisiae. J. E. Wagstaff, S. Klapholz, C. S. Waddell, L. Jensen, and R. Easton Esposito ........................... 3532-3544 Saccharomyces cerevisiae CYCI mRNA 5'-End Positioning: Analysis by In Vitro Mutagenesis, Using Synthetic Duplexes with Random Mismatch Base Pairs. J. Bryan McNeil and Michael Smith ................................... 3545-3551 Effect of Dimethyl Sulfoxide on Human Carcinoma Cells, Inhibition of Plasmino- gen Activator Synthesis, Change in Cell Morphology, and Alteration of Re- sponse to Cholera Toxin. L. Ossowski and D. Belin ..... ............... 3552-3559 Characterization of the Multigene Family Encoding the Mouse S16 Ribosomal Protein: Strategy for Distinguishing an Expressed Gene from Its Processed Pseudogene Counterparts by an Analysis of Total Genomic DNA. Michael Wagner and Robert P. Perry .......................................... 3560-3576 Isolation of a Simian Virus 40 T-Antigen-Positive, Transformation-Resistant Cell Line by Indirect Selection. Kevin W. Ryan, Joan B. Christensen, Michael J. Imperiale, and William W. Brockman................................ 3577-3582 Selective Translational Regulation of Ribosomal Protein Gene Expression during Early Development of Drosophila melanogaster. Mark A. Kay and Marcelo Jacobs-Lorena .................. .................................... 3583-3592 Autogenous Regulation of the Positive Regulatory qa-lF Gene in Neurospora crassa. Virginia B. Patel and Norman H. Giles ........................ 3593-3599 Electron Microscopic Heteroduplex Mapping Identifies Regions of the engrailed Locus That Are Conserved between Drosophila melanogaster and Drosophila virilis. Judith A. Kassis, Mei Lie Wong, and Patrick H. O'Farrell ....... 3600-3609 Isolation of Monoclonal Antibodies Specific for the Human c-myc Proto-Oncogene Product. Gerard 1. Evan, George K. Lewis, Gary Ramsay, and J. Michael Bishop ................ ............................................. 3610-3616 Transforming Activity of DNA Fragments from Normal Human Lymphocytes Re- sults from Spontaneous Activation of a c-Ha-rasl Gene. R. Schafer, S. Griegel, 1. Schwarte, S. Geisse, 0. Traub, and K. Willecke .............. 3617-3620 Continiued on following page Continued from preceding page Can ACG Serve as an Initiation Codon for Protein Synthesis in Eucaryotic Cells? Carl W. Anderson and Elizabeth Buzash-Pollert ........................ 3621-3624 Acquisition of an Intracisternal A-Particle Element by a Translocated c-myc Gene in a Murine Plasma Cell Tumor. Robert Greenberg, Robert Hawley, and Kenneth B. Marcu.................................................. 3625-3628 Phosphorylation and Protein Synthetic Events in Xenopuslaevis Oocytes Micro- injected with pp6Ov.src Jordan G. Spivack and James L. Maller.......... 3629-3633 Structure of the Rat a,-Acid Glycoprotein Gene. Yu-Cheng J. Liao, John M. Taylor, James L. Vannice, Gary A. Clawson, and Edward A. Smuckler... 3634-3639 Isolation of Antibodies for Phosphotyrosine by Immunization with a v-abl Onco- gene-Encoded Protein. Jean Y. J. Wang ............................... 3640-3643 Developmental Expression of Rat Transforming Growth Factor-a mRNA. David C. Lee, Rosemary Rochford, George J. Todaro, and Luis P. Villarreal .... 3644-3646 DNA-Mediated Transformation of Chiamydomonas reinhardi Cells: Use of Amino- glycoside 3'-Phosphotransferase as a Selectable Marker. Seyed E. Hasnain, Elias K. Manavathu, and Wai-Choi Leung ............................. 3647-3650 Date of Issue: 27 November 1985.