ω-Conotoxin-MVIIA ω-CnTx-MVIIA - omega conotoxin MVIIA - #08CON001 - CAS : 107452-89-1 Product information Animal toxins for life-sciences

ω-Conotoxin MVIIA, a potent blocker of Cav2.2 www.smartox-biotech.com

Phone : +33(0) 456 520 869 ω-conotoxin MVIIA (omega conotoxin MVIIA) has been isolated from the venom of the Fax : +33(0) 456 520 868 cone Conus magus. Omega-conotoxins act at presynaptic membranes, they bind and [email protected] block voltage-sensitive calcium channels (VSCC). ω-conotoxin MVIIA blocks N-type voltage-gated calcium channels (Cav2.2/CACNA1B). ω-conotoxin MVIIA is available as Smartox Biotechnology analgesic drug under the name Prialt®. It blocks acute pain in patients who no longer 570 rue de la chimie obtain relief from opiate drugs. It is 100 to 1.000 times more potent than morphine. This 38400 Saint Martin d’Hères toxin blocks calcium channels and disables nerves that transmit pain signals. France

Prices

 100 µg – 100 € Technical information  500 µg – 250 €  1 mg – 425 €

AA sequence: Cys1-Lys-Gly-Lys-Gly-Ala-Lys-Cys8-Ser-Arg-Leu-Met-Tyr-Asp-Cys15-Cys16- 20 25 Related products Thr-Gly-Ser-Cys -Arg-Ser-Gly-Lys-Cys -NH2 Disulfide bridges: Cys1-Cys16, Cys8-Cys20 and Cys15-Cys25  Length (aa): 25 Solubility: water and saline buffer ω-Conotoxin- SO3 - #08CON013 FormulaC H N O S CAS number: 107452-89-1 102 172 36 32 7  ω-Conotoxin-MVIIC - Molecular Weight: 2639.18 Da Source: Synthetic #08CON002 Appearance: White lyophilized solid Purity rate: > 95 %  SNX482 - #08SNX001  ω-agatoxin-IVA - #11AGA001  ω-Conotoxin-GVIA- # 08CON003

References Toxin of the month – free sample program  Miljanich, G. P.- Curr Med Chem Each month, Smartox Biotechnology offers a sample of a selected  Olivera, B. M., et al.- toxin for absolutely free. To be informed, visit our website each Biochemistry. month, subscribe our newsletter or follow us on social networks.  Bowersox SS, Luther R- Clic HERE Toxicon

Ordering information

Range of blockers Smartox products are available worldwide. To place an order, please contact us by phone or Voltage-gated sodium channels Acid-sensing ion channels email or find out your local Voltage-gated calcium channels Chloride channels Potassium channels Nicotinic acetylcholine receptors distributor on our website. We  Voltage-gated potassium channels Purinergic receptors accept credit card payment.  Calcium activated potassium channels TRP channels

 hERG channel Mechanosensitive ion channels  Inward rectifying potassium channels NMDA receptors

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