JOURNAL OF VIROLOGY
Volume 63 June 1989 No. 6
ANIMAL VIRUSES Identification of Temperature-Sensitive Mutants of Vaccinia Virus That Are Defective in Conversion of Concatemeric Replicative Intermediates to the Mature Linear DNA Genome. A. M. DeLange ...... 2437-2444 Biosynthesis and Processing of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins: Effects of Monensin on Glycosylation and Transport. Robin L. Dewar, M. B. Vasudevachari, V. Natarajan, and Norman P. Salzman 2452-2456 Genetic and Molecular Analyses of Spontaneous Mutants of Human Rhinovirus 14 That Are Resistant to an Antiviral Compound. Beverly A. Heinz, Roland R. Rueckert, Deborah A. Shepard, Frank J. Dutko, Mark A. McKinlay, Marilyn Fancher, Michael G. Rossmann, John Badger, and Thomas J. Smith...... 2476-2485 DNA Binding by the Herpes Simplex Virus Type 1 ICP4 Protein Is Necessary for Efficient Down Regulation of the ICPO Promoter. James Resnick, Branin A. Boyd, and Mary L. Haffey...... 2497-2503 ICP4-Binding Sites in the Promoter and Coding Regions of the Herpes Simplex Virus gD Gene Contribute to Activation of In Vitro Transcription by ICP4. Davol G. Tedder, Roger D. Everett, Kent W. Wilcox, Peter Beard, and Lewis I. Pizer...... 2510-2520 Cell-Associated West Nile Flavivirus Is Covered with E+Pre-M Protein Heterodimers Which Are Destroyed and Reorganized by Proteolytic Cleavage during Virus Release. Gerd Wengler and Gisela Wengler ...... 2521-2526 Analysis of gag Proteins from Mouse Mammary Tumor Virus. Amnon Hizi, Louis E. Henderson, Terry D. Copeland, Raymond C. Sowder, Henry C. Krutzsch, and Stephen Oroszlan...... 2543-2549 Role of Human Immunodeficiency Virus Type 1-Specific Protease in Core Protein Maturation and Viral Infectivity. Cheng Peng, Bao K. Ho, Tse Wen Chang, and Nancy T. Chang ...... 2550-2556 Control Elements Situated Downstream of the Major Transcriptional Start Site Are Sufficient for Highly Efficient Polyomavirus Late Transcription. Brigitte Bourachot, Moshe Yaniv, and Philippe Herbomel...... 2567-2577 Proteaselike Sequence in Hepatitis B Virus Core Antigen Is Not Required for e Antigen Generation and May Not Be Part of an Aspartic Acid-Type Protease. Michael Nassal, Peter R. Galle, and Heinz Schaller...... 2598-2604 Adenovirus Early Region 4 Encodes Two Gene Products with Redundant Effects in Lytic Infection. Min-Mei Huang and Patrick Hearing ...... 2605-2615 The Palindromic LTR-LTR Junction of Moloney Murine Leukemia Virus Is Not an Efficient Substrate for Proviral Integration. Leslie I. Lobel, John E. Murphy, and Stephen P. Goff...... 2629-2637 A Promoter of Epstein-Barr Virus That Can Function during Latent Infection Can Be Transactivated by EBNA-1, a Viral Protein Required for Viral DNA Replication during Latent Infection. Bill Sugden and Noreen Warren ...... 2644-2649 A Point Mutational Analysis of Human Papillomavirus Type 16 E7 Protein. Caroline Edmonds and Karen H. Vousden...... 2650-2656
Continued on following page Continued from preceding page
Multiple EBNA1-Binding Sites Are Required To Form an EBNAl-Dependent Enhancer and To Activate a Minimal Replicative Origin within oriP of Epstein-Barr Virus. Doreen A. Wysokenski and John L. Yates ...... 2657-2666 Oligomeric Structure of gp4l, the Transmembrane Protein of Human Immuno- deficiency Virus Type 1. Abraham Pinter, William J. Honnen, Shermaine A. Tilley, Constantin Bona, Habib Zaghouani, Miroslaw K. Gorny, and Susan Zolla-Pazner ...... 2674-2679 Nucleotide Sequences at Recombinational Junctions Present in Pseudorabies Virus Variants with an Invertible L Component. Zhiqiang Lu, Jean M. DeMarchi, Linda Harper, Glenn F. Rall, and Tamar Ben-Porat ...... 2690-2698 Regulated Expression of Early and Late RNAs and Proteins from the Human Cytomegalovirus Immediate-Early Gene Region. Richard M. Stenberg, Alison S. Depto, James Fortney, and Jay A. Nelson...... 2699-2708 DNA Sequences That Regulate Expression of a Vaccinia Virus Late Gene (L65) and Interact with a DNA-Binding Protein from Infected Cells. Jeffrey N. Miner and Dennis E. Hruby...... 2726-2736 Regulated Expression of the Feline Panleukopenia Virus P38 Promoter on Extra- chromosomal FPV/EBV Chimeric Plasmids. Dahn L. Clemens and Jonathan 0. Carlson ...... 2737-2745 Negative Regulatory Element Associated with Potentially Functional Promoter and Enhancer Elements in the Long Terminal Repeats of Endogenous Murine Leukemia Virus-Related Proviral Sequences. Lan-Yang Ch'ang, Wen K. Yang, Fred E. Myer, and Den-Mei Yang ...... 2746-2757 Identification of Immediate-Early-Type cis-Response Elements in the Promoter for the Ribonucleotide Reductase Large Subunit from Herpes Simplex Virus Type 2. James P. Wymer, Theodore D. Chung, Yung-Nien Chang, Gary S. Hayward, and Laure Aurelian ...... 2773-2784 Analysis of a Large-T-Antigen Variant Expressed in Simian Virus 40- Transformed Mouse Cell Line riKS-A. Said Dora, Claudia Schwarz, Martina Baack, Adolf Graessmann, and Rolf Knippers...... 2820-2828 Cloning and Partial DNA Sequencing of Two New Human Papillomavirus Types Associated with Condylomas and Low-Grade Cervical Neoplasia. Attila T. Lorincz, Allison P. Quinn, Mindy D. Goldsborough, Brian J. Schmidt, and Gary F. Temple...... 2829-2834 Transcription Inhibition Site on the M Protein of Vesicular Stomatitis Virus Located by Marker Rescue of Mutant ts023(III) with M-Gene Expression Vectors. Yan Li, Lizhong Luo, and Robert R. Wagner ...... 2841-2843 Retrovirus Vectors Containing an Internal Attachment Site: Evidence that Circles Are Not Intermediates to Murine Retrovirus Integration. James Ellis and Alan Bernstein ...... 2844-2846 Genetic and Biochemical Characterization of the Thymidine Kinase Gene from Herpesvirus of Turkeys. Sandra L. Martin, Diane 1. Aparisio, and Pradip K. Bandyopadhyay ...... 2847-2852 Mice Immunized with Recombinant Vaccinia Virus Expressing Dengue 4 Virus Structural Proteins with or without Nonstructural Protein NS1 Are Protected against Fatal Dengue Virus Encephalitis. Michael Bray, Bangti Zhao, Lewis Markoff, Kenneth H. Eckels, Robert M. Chanock, and Ching-Juh Lai ...... 2853-2856
Continued on following page Continued from preceding page
Identification of a Region within the Human Immunodeficiency Virus Type 1 Long Terminal Repeat That Is Essential for Transactivation by the Hepatitis B Virus Gene X. Jr-Shin Twu, Craig A. Rosen, William A. Haseltine, and William S. Robinson ...... 2857-2860 Aphidicolin Resistance in Herpes Simplex Virus Type 1 Appears To Alter Substrate Specificity in the DNA Polymerase. Jennifer D. Hall and Suann Woodward...... 2874-2876 Hydroxyproline in the Major Capsid Protein VP1 of Polyomavirus. John W. Ludlow and Richard A. Consigli...... 2881-2884
VIRUS-CELL INTERACTIONS Stimulation of Chloramphenicol Acetyltransferase mRNA Translation by Reovirus Capsid Polypeptide cr3 in Cotransfected COS Cells. Michael Giantini and Aaron J. Shatkin...... 2415-2421 Propagation of Human Parvovirus B19 in Primary Culture of Erythroid Lineage Cells Derived from Fetal Liver. Nobuo Yaegashi, Hiroyuki Shiraishi, Toshikazu Takeshita, Masataka Nakamura, Akira Yajima, and Kazuo Sugamura ...... 2422-2426 Cytocidal Effect of Tumor Necrosis Factor on Cells Chronically Infected with Human Immunodeficiency Virus (HIV): Enhancement of HIV Replication. Toshifumi Matsuyama, Yoshiaki Hamamoto, Gen-Ichiro Soma, Den'lchi Mizuno, Naoki Yamamoto, and Nobuyuki Kobayashi...... 2504-2509 Induction of Human Interferon Gene Expression Is Associated with a Nuclear Factor That Interacts with the NF-KB Site of the Human Immunodeficiency Virus Enhancer. J. Hiscott, D. Alper, L. Cohen, J. F. Leblanc, L. Sportza, A. Wong, and S. Xanthoudakis ...... 2557-2566 Role of SPl-Binding Domains in In Vivo Transcriptional Regulation of the Human Immunodeficiency Virus Type 1 Long Terminal Repeat. David Harrich, Joseph Garcia, Foon Wu, Ronald Mitsuyasu, Joseph Gonzalez, and Richard Gaynor...... 2585-2591 Development and Characterization of an Fv-1-Sensitive Retrovirus-Packaging System: Single-Hit Titration Kinetics Observed in Restrictive Cells. Lawrence R. Boone, Cynthia L. Innes, Paul L. Glover, and Elwood Linney...... 2592-2597 Regulation of the Interferon-Inducible IFI-78K Gene, the Human Equivalent of the Murine Mx Gene, by Interferons, Double-Stranded RNA, Certain Cytokines, and Viruses. Jean-Francois Goetschy, Helmut Zeller, Jean Content, and Michel A. Horisberger ...... 2616-2622 Effect of Proviral Insertion on Transcription of the Murine B2mb Gene. Wayne N. Frankel, Terry A. Potter, and T. V. Rajan...... 2623-2628 Features of Two Hepatitis B Virus (HBV) DNA Integrations Suggest Mechanisms of HBV Integration. Okio Hino, Keiko Ohtake, and C. E. Rogler ...... 2638-2643 Replication-Defective Vectors of Reticuloendotheliosis Virus Transduce Exogenous Genes into Somatic Stem Cells of the Unincubated Chicken Embryo. Robert A. Bosselman, Rou-Yin Hsu, Tina Boggs, Sylvia Hu, Joan Bruszewski, Susan Ou, Larry Souza, Lee Kozar, Frank Martin, Margery Nicolson, William Rishell, Joseph A. Schultz, Kenneth M. Semon, and R. Gregory Stewart...... 2680-2689
Continued on following page Continued from preceding page
The Cellular Transcription Factor E2f Requires Viral ElA and E4 Gene Products for Increased DNA-Binding Activity and Functions To Stimulate Adenovirus E2A Gene Expression. Lee E. Babiss ...... 2709-2717 Inhibition of Simian Virus 40 T-Antigen Expression by Cellular Differentiation. David N. Estervig, Parviz Minoo, Chin-Yuan Tzen, and Robert E. Scott 2718-2725 Overlapping Octamer and TAATGARAT Motifs in the VF65-Response Elements in Herpes Simplex Virus Immediate-Early Promoters Represent Independent Binding Sites for Cellular Nuclear Factor III. Colette M. J. apRhys, Dolores M. Ciufo, Edward A. O'Neill, Thomas J. Kelly, and Gary S. Hayward...... 2798-2812 Suppression of UAA and UGA Termination Codons in Mutant Murine Leukemia Viruses. Ya-Xiong Feng, Judith G. Levin, Dolph L. Hatfield, Timothy S. Schaefer, Robert J. Gorelick, and Alan Rein ...... 2870-2873
VIRAL AND CELLULAR ONCOGENES The Transforming Domain Alone of the Latent Membrane Protein of Epstein- Barr Virus Is Toxic to Cells When Expressed at High Levels. Wolfgang Hammerschmidt, Bill Sugden, and Vijay R. Baichwal ...... 2469-2475 Structure of the Marek's Disease Virus BamHI-H Gene Family: Genes of Putative Importance for Tumor Induction. Guy Bradley, Masanobu Hayashi, Gerald Lancz, Akiko Tanaka, and Meihan Nonoyama ...... 2534-2542 Host Cell-Dependent Regulation of Growth Transformation-Associated Epstein- Barr Virus Antigens in Somatic Cell Hybrids. Bertha Contreras-Salazar, George Klein, and Maria G. Masucci ...... 2768-2772 The Human Cytomegalovirus mtrll Colinear Region in Strain Tanaka Is Transformation Defective. Nazma Jahan, Abdur Razzaque, John Brady, and Leonard J. Rosenthal ...... 2866-2869 Molecular Cloning of an Oncogenic Replication-Competent Virus That Causes Lymphoproliferative Disease in Turkeys. Eva Gak, Abraham Yaniv, Ayelet Chajut, Marius lanconescu, Steven R. Tronick, and Arnona Gazit 2877-2880
BACTERIAL VIRUSES Analysis of Near-Neighbor Contacts in Bacteriophage T4 Wedges and Hubless Baseplates by Using a Cleavable Chemical Cross-Linker. Norman R. M. Watts and David H. Coombs ...... 2427-2436
PLANT VIRUSES Artificial Cleavage Site Recognized by Plum Pox Potyvirus Protease in Escherichia coli. Juan Antonio Garcia, Jose Luis Riechmann, and Sonia Lain ...... 2457-2460
VIRAL PATHOGENESIS AND IMMUNITY Epitope Mapping of Neutralizing Monoclonal Antibodies against Duck Hepatitis B Virus. Ramsey C. Cheung, William S. Robinson, Patricia L. Marion, and Harry B. Greenberg...... 2445-2451 Suppression of Rous Sarcoma Virus-Induced Tumor Formation by Preinfection with Viruses Encoding src Protein with Novel N Termini. Irwin H. Gelman and Hidesaburo Hanafusa...... 2461-2468
Continued on following page Continued from preceding page
Dengue Virus-Specific Murine T-Lymphocyte Proliferation: Serotype Specificity and Response to Recombinant Viral Proteins. Alan L. Rothman, Ichiro Kurane, Yi-Ming Zhang, Ching-Juh Lai, and Francis A. Ennis...... 2486-2491 Change in Host Cell Tropism Associated with In Vitro Replication of Equine Infectious Anemia Virus. Susan Carpenter and Bruce Chesebro ...... 2492-2496 CD4-Independent Infection of Human Neural Cells by Human Immunodeficiency Virus Type 1. Janet M. Harouse, Charles Kunsch, Heather T. Hartle, Mark A. Laughlin, James A. Hoxie, Brian Wigdahl, and F. Gonzalez- Scarano...... 2527-2533 Lentivirus-Induced Interferon Inhibits Maturation and Proliferation of Monocytes and Restricts the Replication of Caprine Arthritis-Encephalitis Virus. M. Christine Zink and Opendra Narayan ...... 2578-2584 Detection of Murine Cytomegalovirus DNA in Circulating Leukocytes Harvested during Acute Infection of Mice. James F. Bale, Jr., and Marsha E. O'Neil ...... 2667-2673 Induction of Immune Response to Influenza Virus with Anti-Idiotypic Antibodies. E. Margot Anders, Georgia P. Kapaklis-Deliyannis, and David 0. White 2758-2767 Bacterial Lipopolysaccharide and Gamma Interferon Induce Transcription of Beta Interferon mRNA and Interferon Secretion in Murine Macrophages. Sandra Gessani, Filippo Belardelli, Antonella Pecorelli, Patrizia Puddu, and Corrado Baglioni...... 2785-2789 Antiviral Antibodies Stimulate Production of Reactive Oxygen Species in Cultured Canine Brain Cells Infected with Canine Distemper Virus. T. Burge, C. Griot, M. Vandevelde, and E. Peterhans ...... 2790-2797 Enhanced Virus Replication and Inhibition of Lymphocytic Choriomeningitis Virus Disease in Anti-Gamma Interferon-Treated Mice. T. P. Leist, M. Eppler, and R. M. Zinkernagel...... 2813-2819 Identification of Proteins Specific for Human Herpesvirus 6-Infected Human T Cells. N. Balachandran, Roberta E. Amelse, Wei W. Zhou, and Cheow K. Chang ...... 2835-2840 Latency-Associated Transcript but Not Reactivatable Virus Is Present in Sensory Ganglion Neurons after Inoculation of Thymidine Kinase-Negative Mutants of Herpes Simplex Virus Type 1. Richard B. Tenser, Kathleen A. Hay, and Wade A. Edris...... 2861-2865
Date of Issue: 12 May 1989