DOCSLIB.ORG

Saturday, April 14, 2007

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Saturday, April 14, 2007 Saturday, April 14, 2007 8:00-10:00 AM Educational Sessions Systems Biology as an Integrative Approach to Cancer, Arul M. Chinnaiyan, Chairperson, Room 403 A-B, Los Angeles Convention How to Design and Interpret Large-Scale Sequence Analyses of Center, p. 65 Human Cancer, Victor E. Velculescu, Chairperson, Room 408 A-B, Los Angeles Convention Center, p. 57 Targeted Cancer Therapy: Mono-specific versus Multi-targeted Strategies, Axel Ullrich, Chairperson, Concourse E, Los Angeles Manipulating the Immune System in Cancer Immunotherapy, Convention Center, p. 65 James P. Allison, Chairperson, Petree C, Los Angeles Convention Saturday Event Schedule Center, p. 58 Targeted Delivery of siRNA and Small Molecule Inhibitors, Jackson B. Gibbs, Chairperson, Concourse F, Los Angeles Convention Modeling Chemoprevention in Mice: The Next Generation, Cory Center, p. 66 Abate-Shen, Chairperson, Room 515 B, Los Angeles Convention Center, p. 58 The Ras Pathway: From Cancer Biology to Translational Opportunities, Dafna Bar-Sagi, Chairperson, Room 304 A-C, Los Novel Approaches to Drug Delivery in Cancer, Mark E. Davis, Angeles Convention Center, p. 66 Chairperson, Room 304 A-C, Los Angeles Convention Center, p. 59 Oxidative Stress and Senescence, Amato J. Giaccia, Chairperson, Room 515 A, Los Angeles Convention Center, p. 59 10:15 AM-12:15 PM Methods Workshops The Polygenic Basis of Phenotypic Variation and Disease: Lessons from Humans and Model Organisms, Bruce A. J. Ponder, Advances in Imaging: From Molecules and Live-Cell Research to Chairperson, Petree D, Los Angeles Convention Center, p. 60 Animal Models and Clinical Applications, Jiri Bartek, Chairperson, Room 515 B, Los Angeles Convention Center, p. 67 Therapeutic Cancer Targets in the Wnt Pathway, Hans Clevers, Chairperson, Room 403 A-B, Los Angeles Convention Center, p. 60 Clinical Trials, Part I: Recent Innovations in Oncology Clinical Trails, Donald A. Berry, Chairperson, Room 515 A, Los Angeles Validating Therapeutic Targets: In Vivo Models and Clinical Convention Center, p. 67 Responses, Lynda Chin, Chairperson, Concourse E, Los Angeles Convention Center, p. 61 11:00 AM-5:00 PM Professional Advancement Series 8:00-10:00 AM Methods Workshops Second WICR Leadership Development Workshop, Tona M. Approaches to Cancer Genetics in Humans, Arnold J. Levine, Gilmer, Chairperson, Sierra Ballroom, Wilshire Grand Hotel, p. 68 Chairperson, Concourse F, Los Angeles Convention Center, p. 62 siRNA Screens: A Tool for Understanding Targets, Stephen H. Friend, Chairperson, Room 502 A-B, Los Angeles Convention Center, 11:30 AM-5:00 PM Professional Advancement p. 62 Series Tenth Annual Grant Writing Workshop for Associate Members, Concourse Ballroom (Second Level), Los Angeles Marriott Hotel, p. 68 10:15 AM-12:15 PM Educational Sessions Cancer Biomarkers: Predictors of Prognosis and Response, William S. Dalton, Chairperson, Room 502 A-B, Los Angeles 1:00-3:00 PM Educational Sessions Convention Center, p. 63 Metabolism and Cancer, Karen H. Vousden, Chairperson, Controlling Epigenetic Programs: Consequences for Stem Cells Room 502 A-B, Los Angeles Convention Center, p. 69 and Carcinogenesis, Thea D. Tlsty, Chairperson, Petree C, Los Models and Assays for Drug Discovery and Development, J. Angeles Convention Center, p. 63 Martin Brown, Chairperson, Room 515 B, Los Angeles Convention Facilitating Collaborations Between Clinicians and Basic Center, p. 69 Researchers in the Era of Integrated Translational Research, Non-invasive Imaging (MRI, PET, and Optical Imaging) in Paul Workman, Chairperson, Room 408 A-B, Los Angeles Convention Detecting Disease, Evaluating Responses to Therapy, and Center, p. 64 Guiding Subsequent Treatment, Kevin M. Brindle, Chairperson, Inflammation and Cancer, Lisa M. Coussens, Chairperson, Petree D, Room 515 A, Los Angeles Convention Center, p. 70 Los Angeles Convention Center, p. 64 40 American Association for Cancer Research • Annual Meeting 2007 Saturday, April 14, 2007 Plasma Biomarkers: Applications in Oncology, Gary J. Kelloff, 3:15-5:15 PM Methods Workshops Chairperson, Room 408 A-B, Los Angeles Convention Center, p. 70 Measuring the Epigenome, Christoph Plass, Chairperson, Petree C, Rho GTPases: Cytoskeleton and Cancer, Christopher J. Marshall, Los Angeles Convention Center, p. 78 Chairperson, Room 511 A-C, Los Angeles Convention Center, p. 71 Three-Dimensional Culture Models, Joan S. Brugge, Chairperson, The Epigenetic Road from Stem Cells to Cancer, Kornelia Polyak, Room 502 A-B, Los Angeles Convention Center, p. 78 Chairperson, Petree D, Los Angeles Convention Center, p. 71 Saturday Event Schedule Translational Cancer Research in the Future: The Report of the National Cancer Institute Translational Research Working Group, William G. Nelson V and Lynn M. Matrisian, Co-Chairpersons, 5:15-6:45 PM Clinical and Basic Room 403 A-B, Los Angeles Convention Center, p. 72 Interface Sessions Breast Cancer, Monica Morrow, Chairperson, Concourse E, Los Angeles Convention Center, p. 79 1:00-3:00 PM Methods Workshops Central Nervous System Cancers, Henry S. Friedman, Chairperson, Room 403 A-B, Los Angeles Convention Center, p. 79 Clinical Trials, Part II: Why Oncology Drug Development Usually Fails– Bad Drugs, Bad Designs, or Bad Patient Selection?, Colon Cancer: A Decade of Basic and Clinical Progress, Mark J. Ratain, Chairperson, Concourse F, Los Angeles Convention James L. Abbruzzese, Chairperson, Concourse F, Los Angeles Center, p. 73 Convention Center, p. 80 Interpreting Chromosomal Copy Number Aberration in the Gynecologic Cancers: Current Status and Future Directions, Cancer Genome, Cameron W. Brennan, Chairperson, Room 304 A-C, Robert F. Ozols, Chairperson, Room 515 A, Los Angeles Convention Los Angeles Convention Center, p. 73 Center, p. 80 Recent Advances in Mouse Models of Cancer, Michael M. Shen, Hematologic Malignancies, Kanti R. Rai, Chairperson, Petree D, Los Chairperson, Concourse E, Los Angeles Convention Center, p. 74 Angeles Convention Center, p. 80 Identification and Exploitation of Molecular Targets in Pediatric Cancers: Expectations from and Challenges to Genomic Approaches to Therapy, Gregory H. Reaman, Chairperson, Room 3:15-5:15 PM Educational Sessions 304 A-C, Los Angeles Convention Center, p. 81 Alternative Approaches to Small Molecule Drug Discovery Lung and Head and Neck Cancers, Everett E. Vokes, Chairperson, (protein-protein interactions), William R. Sellers and Room 502 A-B, Los Angeles Convention Center, p. 82 Carlos Garcia-Echeverria, Co-Chairpersons, Petree D, Los Angeles Convention Center, p. 75 Melanoma and Other Cutaneous Malignancies, John M. Kirkwood, Chairperson, Room 515 B, Los Angeles Convention Center, MicroRNAs, Carlo M. Croce, Chairperson, Concourse E, Los Angeles p. 82 Convention Center, p. 75 Sarcoma, Laurence H. Baker, Chairperson, Room 408 A-B, Los Preneoplasia: Predicting the Behavior of the Early Lesion, Angeles Convention Center, p. 83 Rebecca Fitzgerald, Chairperson, Room 515 B, Los Angeles Convention Center, p. 76 Targeting Protein Translation in Cancer, Nahum Sonenberg, Chairperson, Room 515 A, Los Angeles Convention Center, p. 76 5:45-7:00 PM Targeting Ras Pathways in Cancer, Mariano Barbacid, Tenth Annual AACR-Women in Cancer Research Chairperson, Room 304 A-C, Los Angeles Convention Center, p. 77 Charlotte Friend Memorial Lecture Toll Receptors, Immunity, and Cancer, Louis M. Weiner, Janet S. Butel, Hall B, Los Angeles Convention Center, p. 84 Chairperson, Room 403 A-B, Los Angeles Convention Center, p. 77 7:00-9:00 PM Professional Advancement Series Roundtable: Careers in Clinical and Translational Cancer Research, Eric H. Rubin, Chairperson, San Diego Room, Westin Bonaventure Hotel, p. 85 April 14-18, 2007 • Los Angeles, CA 41 Sunday, April 15, 2007 7:30-9:15 AM AACR Centennial Ceremony 9:15 AM-12:30 PM Opening Plenary Session Hall A, Los Angeles Convention Center, p. 88 Translating a Century of Science into a Future of Cancer Prevention and Cures, Ronald A. DePinho, Chairperson, Hall A, Los Angeles Convention Center, p. 92 8:00 AM-12:00 PM Poster Sessions Exhibit Hall, Los Angeles Convention Center 12:00-4:00 PM Professional Advancement PR 1 Cox-2 and Selenium, p. 94 Series PR 2 Survivorship, Quality of Life, and Supportive Care, p. Undergraduate Student Caucus and Poster Competition, Pacific 95 Ballroom, Wilshire Grand Hotel, p. 124 EP 1 Epidemiologic Methods, Risk Factors, and Incidence, p. 96 EP 2 Occupation, Smoking, Other Exposures, and Cancer Risk, p. 97 1:00-2:30 PM Forums CG 1 Genitourinary and Gastrointestinal Carcinogenesis, A Status Report of Breast Cancer Chemoprevention Trials: Past, p. 98 Present, and Future, D. Lawrence Wickerham, Moderator, Petree C, Los Angeles Convention Center, p. 125 Sunday Event Schedule CL 1 Prognostic Value of Chromosomal and DNA-based Alterations, p. 99 What Are the Best Preclinical Models for Cancer Drug Discovery, Robert A. Weinberg, Moderator, Concourse E, Los CL 2 Tumor Proteins in Genitourinary and Other Cancers, Angeles Convention Center, p. 125 p. 100 CL 3 Tumor Proteins in NSCLC and Gastrointestinal Cancers, Opportunistic Screening for Prostate Cancer: The Up and Down p. 101 Sides of PSA Testing, Fritz H. Schröder,Moderator, Petree D, Los Angeles Convention Center, p. 125 IM 1 Immune Suppression and Escape, p. 102 Therapeutic Manipulations of Tumor Suppressors, Gerard I. CB 1 Epigenetic Markers of Cancer 1, p. 103 Evan, Moderator, Concourse F, Los Angeles Convention Center, p. 125 CB 2 Intracellular Signaling 1, p. 104 CB 3 Intracellular Signaling 2, p. 105 CB 4 Intracellular Signaling 3, p. 106 1:00-3:00 PM Drug Development Track CB 5 Molecular Genetics 1, p. 107 Special Session 1 CB 6 Molecular Genetics 2, p. 108 New Drugs on the Horizon 1, John T. Hunt and CB 7 Positive and Negative Growth Signaling, p. 109 Judith S. Sebolt-Leopold, Co-Chairpersons, Hall A, Los Angeles CB 8 Tumor Suppressors and Tumor Cell Death, p. 110 Convention Center, p. 126 TB 1 Metastasis Suppressor and Promoter Genes, p. 111 TB 2 Mouse Models of Cancer 1: Imaging Technologies, p. 112 TB 3 Pediatric Cancer Biology and Clinical Investigation, p. 113 TB 4 Tumor Microenvironment 1, p. 114 TB 5 Tumor Microenvironment 2, p.
Load more

Recommended publications
  • The Transcription Factor Hey and Nuclear Lamins Specify and Maintain
    RESEARCH ARTICLE The transcription factor Hey and nuclear lamins specify and maintain cell identity Naama Flint Brodsly1†, Eliya Bitman-Lotan1†, Olga Boico1, Adi Shafat1, Maria Monastirioti2, Manfred Gessler3, Christos Delidakis2, Hector Rincon-Arano4, Amir Orian1* 1Rappaport Research Institute and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel; 2Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology - Hellas (FORTH), Heraklion, Greece; 3Biocenter of Developmental Biochemistry, University of Wu¨ rzburg, Wu¨ rzburg, Germany; 4Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, United States Abstract The inability of differentiated cells to maintain their identity is a hallmark of age- related diseases. We found that the transcription factor Hey supervises the identity of differentiated enterocytes (ECs) in the adult Drosophila midgut. Lineage tracing established that Hey-deficient ECs are unable to maintain their unique nuclear organization and identity. To supervise cell identity, Hey determines the expression of nuclear lamins, switching from a stem-cell lamin configuration to a differentiated lamin configuration. Moreover, continued Hey expression is required to conserve large-scale nuclear organization. During aging, Hey levels decline, and EC identity and gut homeostasis are impaired, including pathological reprograming and compromised gut integrity. These phenotypes are highly similar to those observed upon acute targeting of Hey or perturbation of lamin expression in ECs in young adults. Indeed, aging phenotypes were suppressed by continued expression of Hey in ECs, suggesting that a Hey-lamin network *For correspondence: safeguards nuclear organization and differentiated cell identity. [email protected] DOI: https://doi.org/10.7554/eLife.44745.001 †These authors contributed equally to this work Competing interests: The authors declare that no Introduction competing interests exist.
    [Show full text]
  • 2012 Annual Report
    Memorial Sloan-Kettering Cancer Center 2012 ANNUAL REPORT A SHARED VISION A SINGULAR MISSION Nurse practitioner Naomi Cazeau, of the Adult Bone Marrow Transplant Service. PING CHI PHYSICIAN-SCIENTIST 10 STEPHEN SOLOMON ALEXANDER RUDENSKY INTERVENTIONAL IMMUNOLOGIST RADIOLOGIST 16 12 VIVIANE TABAR The clinicians and scientists of NEUROSURGEON Memorial Sloan-Kettering share a vision and 18 a singular mission — to conquer cancer. STEPHEN LONG STRUCTURAL BIOLOGIST They are experts united against a 20 SIMON POWELL complex disease. Each type of cancer R ADIATION ONCOLOGIST 24 ETHEL LAW is different, each tumor is unique. Set free NURSE PRACTITIONER in surroundings that invite the sharing of 26 ideas and resources, they attack the CHRISTINA LESLIE complexity of cancer from every angle COMPUTATIONAL BIOLOGIST and every discipline. 34 SCOTT ARMSTRONG PEDIATRIC ONCOLOGIST 30 TO JORGE REIS-FILHO EXPERIMENTAL PATHOLOGIST CONQUER 38 CANCER 04 Letter from the Chairman and the President A complete version of this report — 42 Statistical Profile which includes lists of our donors, 44 Financial Summary doctors, and scientists — 46 Boards of Overseers and Managers is available on our website at 49 The Campaign for Memorial Sloan-Kettering www.mskcc.org/annualreport. 4 5 Letter from the Chairman In 2012 the leadership of Memorial Sloan-Kettering endorsed Douglas A. Warner III These programmatic investments require leadership and and the President a $2.2 billion investment in a clinical expansion that will set vision. Our new Physician-in-Chief, José Baselga, joined the stage for a changing care paradigm into the next decade us on January 1, 2013. An internationally recognized and beyond.
    [Show full text]
  • ASBMB President Urges Support for NSF Page 2 Experimental Smallpox
    MAY 2004 www.asbmb.org Constituent Society of FASEB AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY ALSO IN THIS ISSUE ASBMB President Urges Support for NSF Page 2 Experimental Smallpox Vaccine Tested Page 9 See You in Boston! “A“A MolecularMolecular ExplorationExploration ofof thethe Cell”Cell” ASBMB Annual Meeting and 8th IUBMB Conference JuneJune 12-16,12-16, 20042004 Boston, Massachusetts IUBMB/ASBMB 2004 “A Molecular Exploration of the Cell” June 12 – 16 Boston, MA American Society for Biochemistry and Molecular Biology Annual Meeting and 8th IUBMB Conference l Biology ■ Mole ■ Chemica cular Recog atics nition ■ nform Ce Bioi llula and r Bi ics och om em te ist Pro Opening Lecture ry First Annual Herbert Tabor/Journal of Biological Chemistry Lectureship Robert J. Lefkowitz, HHMI, Duke University Medical Center Organized by: John D. Scott, HHMI, Vollum Institute; Alexandra C. Newton, UCSD; Julio Celis, Danish Cancer Society, and the 2004 ASBMB Program Planning Committee Cellular Organization and Dynamics Regulation of Gene Expression and Organizer: Harald A. Stenmark, Norwegian Rad. Hosp. Chromosome Transactions Organizer: Joan W. Conaway, Stowers Inst. for Med. Res. Genomics, Proteomics and Bioinformatics Organizers: Charlie Boone, Univ. of Toronto and Signaling Pathways in Disease Michael Snyder, Yale Univ. Organizers: Alexandra Newton, UCSD and John D. Scott, HHMI, Vollum Inst. Integration of Signaling Mechanisms Organizer: Kjetil Tasken, Univ. of Oslo, Norway The Future of Education and Professional Development in the Molecular Life Sciences Molecular and Cellular Biology of Lipids Organizer: J. Ellis Bell, Univ. of Richmond Organizer: Dennis Vance, Univ. of Alberta Molecular Recognition and Catalysis For further information: Organizer: Jack E.
    [Show full text]
  • Redundancy and Specificity F Mechta-Grigoriou Et Al 2379
    Oncogene (2001) 20, 2378 ± 2389 ã 2001 Nature Publishing Group All rights reserved 0950 ± 9232/01 $15.00 www.nature.com/onc The mammalian Jun proteins: redundancy and speci®city Fatima Mechta-Grigoriou1, Damien Gerald1 and Moshe Yaniv*,1 1Unite des virus oncogenes, CNRS URA 1644, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France The AP-1 transcription factor is composed of a mixture transcription factors. These proteins are characterized of homo- and hetero-dimers formed between Jun and Fos by a highly charged, basic DNA binding domain, proteins. The dierent Jun and Fos family members vary immediately adjacent to an amphipathic dimerization signi®cantly in their relative abundance and their domain, referred as the `Leucine zipper' (Kouzarides interactions with additional proteins generating a and Zi, 1988; Landschulz et al., 1988). Dimerization complex network of transcriptional regulators. Thus, is required for speci®c and high anity binding to the the functional activity of AP-1 in any given cell depends palindromic DNA sequence, TGAC/GTCA (Rauscher on the relative amount of speci®c Jun/Fos proteins which et al., 1988; Gentz et al., 1989; Hirai and Yaniv, 1989; are expressed, as well as other potential interacting Ransone et al., 1989; Schuermann et al., 1989; Turner proteins. This diversity of AP-1 components has and Tjian, 1989). The dierent AP-1 dimers exhibit complicated our understanding of AP-1 function and similar DNA binding speci®cities but dier in their resulted in a paucity of information about the precise transactivation eciencies (Chiu et al., 1989; Hirai et role of individual AP-1 members in distinct cellular al., 1990; Kerppola and Curran, 1991b; Suzuki et al., processes.
    [Show full text]
  • Lasker Interactive Research Nom'18.Indd
    THE 2018 LASKER MEDICAL RESEARCH AWARDS Nomination Packet albert and mary lasker foundation November 1, 2017 Greetings: On behalf of the Albert and Mary Lasker Foundation, I invite you to submit a nomination for the 2018 Lasker Medical Research Awards. Since 1945, the Lasker Awards have recognized the contributions of scientists, physicians, and public citizens who have made major advances in the understanding, diagnosis, treatment, cure, and prevention of disease. The Medical Research Awards will be offered in three categories in 2018: Basic Research, Clinical Research, and Special Achievement. The Lasker Foundation seeks nominations of outstanding scientists; nominations of women and minorities are encouraged. Nominations that have been made in previous years are not automatically reconsidered. Please see the Nomination Requirements section of this booklet for instructions on updating and resubmitting a nomination. The Foundation accepts electronic submissions. For information on submitting an electronic nomination, please visit www.laskerfoundation.org. Lasker Awards often presage future recognition of the Nobel committee, and they have become known popularly as “America’s Nobels.” Eighty-seven Lasker laureates have received the Nobel Prize, including 40 in the last three decades. Additional information on the Awards Program and on Lasker laureates can be found on our website, www.laskerfoundation.org. A distinguished panel of jurors will select the scientists to be honored with Lasker Medical Research Awards. The 2018 Awards will
    [Show full text]
  • CSHL AR 1981.Pdf
    ANNUAL REPORT 1981 COLD SPRING HARBOR LABORATORY Cold Spring Harbor Laboratory Box 100, Cold Spring Harbor, New York 11724 1981 Annual Report Editors: Annette Kirk, Elizabeth Ritcey Photo credits: 9, 12, Elizabeth Watson; 209, Korab, Ltd.; 238, Robert Belas; 248, Ed Tronolone. All otherphotos by Herb Parsons. Front and back covers: Sammis Hall, new residence facility at the Banbury Conference Center.Photos by K orab, Ltd. COLD SPRING HARBOR LABORATORY COLD SPRING HARBOR, LONG ISLAND, NEW YORK OFFICERS OF THE CORPORATION Walter H. Page, Chairman Dr. Bayard Clarkson, Vice-Chairman Dr. Norton D. Zinder, Secretary Robert L. Cummings, Treasurer Roderick H. Cushman, Assistant Treasurer Dr. James D. Watson, Director William R. Udry, Administrative Director BOARD OF TRUSTEES Institutional Trustees Individual Trustees Albert Einstein College of Medicine John F. Carr Dr. Matthew Scharff Emilio G. Collado Robert L. Cummings Columbia University Roderick H. Cushman Dr. Charles Cantor Walter N. Frank, Jr. John P. Humes Duke Mary Lindsay Dr. Robert Webster Walter H. Page William S. Robertson Long Island Biological Association Mrs. Franz Schneider Edward Pulling Alexander C. Tomlinson Dr. James D. Watson Massachusetts Institute of Technology Dr. Boris Magasanik Honorary Trustees Memorial Sloan-Kettering Cancer Center Dr. Bayard Clarkson Dr. Harry Eagle Dr. H. Bentley Glass New York University Medical Center Dr. Alexander Hollaender Dr. Claudio Basilico The Rockefeller University Dr. Norton D. Zinder State University of New York, Stony Brook Dr. Thomas E. Shenk University of Wisconsin Dr. Masayasu Nomura Wawepex Society Bache Bleeker Yale University Dr. Charles F. Stevens Officers and trustees are as of December 31, 1981 DIRECTOR'S REPORT 1981 The daily lives of scientists are much less filled now be solvable or whether we must await the re- with clever new ideas than the public must im- ception of some new facts that as yet do not exist.
    [Show full text]
  • Journal of Molecular Biology
    JOURNAL OF MOLECULAR BIOLOGY AUTHOR INFORMATION PACK TABLE OF CONTENTS XXX . • Description p.1 • Audience p.2 • Impact Factor p.2 • Abstracting and Indexing p.2 • Editorial Board p.2 • Guide for Authors p.6 ISSN: 0022-2836 DESCRIPTION . Journal of Molecular Biology (JMB) provides high quality, comprehensive and broad coverage in all areas of molecular biology. The journal publishes original scientific research papers that provide mechanistic and functional insights and report a significant advance to the field. The journal encourages the submission of multidisciplinary studies that use complementary experimental and computational approaches to address challenging biological questions. Research areas include but are not limited to: Biomolecular interactions, signaling networks, systems biology Cell cycle, cell growth, cell differentiation Cell death, autophagy Cell signaling and regulation Chemical biology Computational biology, in combination with experimental studies DNA replication, repair, and recombination Development, regenerative biology, mechanistic and functional studies of stem cells Epigenetics, chromatin structure and function Gene expression Receptors, channels, and transporters Membrane processes Cell surface proteins and cell adhesion Methodological advances, both experimental and theoretical, including databases Microbiology, virology, and interactions with the host or environment Microbiota mechanistic and functional studies Nuclear organization Post-translational modifications, proteomics Processing and function of biologically
    [Show full text]
  • May 2007 ASCB Newsletter
    ASCB M A Y 2 0 0 7 NEWSLETTER VOLUME 30, NUMBER 5 Annual Senate Approves Stem Cell Bills Meeting Once again, the United States Senate has ap- The current federal policy limits federally Program proved a bill that would expand the exist- funded research to research using human Page 8 ing federal human embryon- embryonic stem cell lines ic stem cell policy. The bill, derived before August 9, 2001. S.5, the Stem Cell Research “[N]aturally dead Despite U.S. President Bush’s NIH Enhancement Act of 2007, initial claim that as many as Proponents passed the Senate by a vote of is a scientifi cally 78 stem cell lines would be 63–34. Three Senators who meaningless available to researchers, only 21 Rally Support support stem cell research did lines are actually available. idea. To our not vote. Only two of the nine S.5, the pro-research bill, in Congress new Senators —Sens. Bob knowledge, there would expand the current policy Page 13 Corker (R-TN) and Bob Casey is no scientifi cally to allow investigators to receive (D-PA)—opposed the bill. federal funds for research using A Network of The Senate also passed a credible way to human embryonic stem cells bill that would limit federally determine this derived from IVF clinic excess Our Own funded research to research embryos that would otherwise using human embryonic stem [for embryos].” be destroyed. S.5 combines Page 18 cells derived from “naturally the bill that was passed by the dead” embryos. That bill, House and Senate last year S.30, the Hope Offered through Principled and (H.R.810) but vetoed by President Bush, along Inside Ethical Stem Cell Research Act, was approved with the main components of a second bill 70–28.
    [Show full text]
  • Celebrating 40 Years of Rita Allen Foundation Scholars 1 PEOPLE Rita Allen Foundation Scholars: 1976–2016
    TABLE OF CONTENTS ORIGINS From the President . 4 Exploration and Discovery: 40 Years of the Rita Allen Foundation Scholars Program . .5 Unexpected Connections: A Conversation with Arnold Levine . .6 SCIENTIFIC ADVISORY COMMITTEE Pioneering Pain Researcher Invests in Next Generation of Scholars: A Conversation with Kathleen Foley (1978) . .10 Douglas Fearon: Attacking Disease with Insights . .12 Jeffrey Macklis (1991): Making and Mending the Brain’s Machinery . .15 Gregory Hannon (2000): Tools for Tough Questions . .18 Joan Steitz, Carl Nathan (1984) and Charles Gilbert (1986) . 21 KEYNOTE SPEAKERS Robert Weinberg (1976): The Genesis of Cancer Genetics . .26 Thomas Jessell (1984): Linking Molecules to Perception and Motion . 29 Titia de Lange (1995): The Complex Puzzle of Chromosome Ends . .32 Andrew Fire (1989): The Resonance of Gene Silencing . 35 Yigong Shi (1999): Illuminating the Cell’s Critical Systems . .37 SCHOLAR PROFILES Tom Maniatis (1978): Mastering Methods and Exploring Molecular Mechanisms . 40 Bruce Stillman (1983): The Foundations of DNA Replication . .43 Luis Villarreal (1983): A Life in Viruses . .46 Gilbert Chu (1988): DNA Dreamer . .49 Jon Levine (1988): A Passion for Deciphering Pain . 52 Susan Dymecki (1999): Serotonin Circuit Master . 55 Hao Wu (2002): The Cellular Dimensions of Immunity . .58 Ajay Chawla (2003): Beyond Immunity . 61 Christopher Lima (2003): Structure Meets Function . 64 Laura Johnston (2004): How Life Shapes Up . .67 Senthil Muthuswamy (2004): Tackling Cancer in Three Dimensions . .70 David Sabatini (2004): Fueling Cell Growth . .73 David Tuveson (2004): Decoding a Cryptic Cancer . 76 Hilary Coller (2005): When Cells Sleep . .79 Diana Bautista (2010): An Itch for Knowledge . .82 David Prober (2010): Sleeping Like the Fishes .
    [Show full text]
  • On the Arts and Sciences Academy Inducts 233Rd Class of Members
    american academy of arts & sciences winter 2014 www.amacad.org vol. lxvii, no. 2 american academy of arts & sciences bulletin winter 2014 Bulletin Academy Inducts 233rd Class of Members Class Speakers: Alison Gopnik, Paula Fredriksen, Xiaowei Zhuang, Marc Tessier-Lavigne, and Phyllis M. Wise On the Arts and Sciences Ken Burns and Ernest J. Moniz ALSO: Restoring Justice: The Legacy of Edward H. Levi Middle East Regional Security Challenges: The View from Turkey A View of the Visiting Scholars A View from a Visiting Scholar Point of View: Talks on Education Upcoming Events FEBRUARY MARCH 12th 12th House of the Academy, Cambridge House of the Academy, Cambridge SILA: Staged Reading and Panel Discussion A program about “At Berkeley,” a new about the Future of our Planet documentary by Frederick Wiseman Featuring: Featuring: Robert Jaffe (Massachusetts Institute Robert J. Birgeneau (University of of Technology) California, Berkeley) Chantal Bilodeau (The Arctic Cycle) George W. Breslauer (University of California, Berkeley) Naomi Oreskes (Harvard University) Mark S. Schlissel (Brown University; Staged Reading by University of Michigan) Catalyst Collaborative@MIT Frederick Wiseman (Filmmaker) 15th Fairmont Chicago, Millennium Park Hotel, APRIL Chicago, Illinois 17th Reception for Fellows and Guests with remarks by Alan Alda House of the Academy, Cambridge Growing Pains in a Rising China Featuring: Elizabeth Perry (Harvard University) Ching Kwan Lee (University of California, Los Angeles) Benjamin L. Liebman (Columbia Law School) Barry Naughton (University of California, San Diego) For updates and additions to the calendar, visit www.amacad.org. Reminder to Members The Annual Fund his year’s Annual Fund Campaign will conclude on March 31.
    [Show full text]
  • The Synapse Revealed
    Nobel Prize: Axel and Buck || Dog Genome || DNA Repair FALL 2004 www.hhmi.org/bulletin This neural structure is essential to perception, behavior, thinking, and memory. THE SYNAPSE REVEALED C O N T E N T S Fall 2004 || Volume 17 Number 3 FEATURES 24 28 14 The Synapse Revealed TheBulletin asks [ COVER STORY ] The molecular details of this neural structure give scientists to assess the science education clues on perception, behavior, memory, and thinking. By Steve Olson their children get. 24 Synthesized Thinking Working where the wind comes sweepin’ down the plain, blood researcher Charles Esmon looks for connections that others might miss. By Nancy Ross-Flanigan 28 The Case Against Rote What do scientists think of the science education their kids get? By Marlene Cimons and Laurie J. Vaughan DEPARTMENTS 2 INSTITUTE NEWS HHMI, NIBIB/NIH Collaborate on Interdisciplinary Ph.D. Program 36 03 PRESIDENT’S LETTER A Process of Discovery 04 NOBEL PRIZE A Discerning Obsession U P F R O N T 0 8 Tools Rule 010 Understanding Listeria 012 Bow WOW! NEWS & NOTES 34 Left, Right! Left, Right! 35 In on the Ground Level 36 A Heart’s Critical Start 37 Decoding Key Cancer Toeholds 38 In Search of a Thousand Solutions 39 Teaching the Teachers 40 Jeff Pinard, Fighter 41 Traffic Control 42 Post-Soviet Science 44 HHMI LAB BOOK 39 47 N O T A B E N E 50 U P C L O S E DNA’s Mr. Fix-it 55 Q & A Tracking Cancer in Real Time 56 INSIDE HHMI Full Court Press 57 IN MEMORIAM ON THE COVER: A cultured neuron from the hippocampal brain region, important for converting short term memory to more permanent memory, and for recalling spatial relationships.
    [Show full text]
  • Host Cell Factors in Ovarian Cancer Influencing Efficacy of Oncolytic Aenovirus Dl922-947 Flak, Magdalena Barbara
    Host cell factors in ovarian cancer influencing efficacy of oncolytic aenovirus dl922-947 Flak, Magdalena Barbara The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the author For additional information about this publication click this link. https://qmro.qmul.ac.uk/jspui/handle/123456789/553 Information about this research object was correct at the time of download; we occasionally make corrections to records, please therefore check the published record when citing. For more information contact [email protected] Host Cell Factors in Ovarian Cancer Influencing Efficacy of Oncolytic Adenovirus dl922-947 Magdalena Barbara Flak A thesis submitted to the University of London (Faculty of Science) for the degree of Doctor of Philosophy February 2010 Centre for Molecular Oncology and Imaging Institute of Cancer Barts and the London School of Medicine and Dentistry Charterhouse Square, London EC1M 6BQ 1 I, Magdalena Barbara Flak, hereby confirm that the work presented in this thesis is original and is my own. Work undertaken by others in contribution to this thesis has been clearly indicated. Where information has been derived from other sources, this has been acknowledged and appropriately referenced. Signed ………………………………... 2 Acknowledgments First of all, I would like to thank my supervisor Prof Iain McNeish. He has given me the opportunity to work on this exciting project. But more importantly, Iain, your expertise, encouragment and genuine support have guided me throughout my PhD and allowed me to grow as a scientist and as a person.
    [Show full text]