EMBO | EMBC annual report 2005

EUROPEAN MOLECULAR BIOLOGY ORGANIZATION | EUROPEAN MOLECULAR BIOLOGY CONFERENCE EMBO | EMBC table of contents

introduction preface by Frank Gannon, EMBO 4 preface by Susan Gasser, EMBO Council 6 preface by Marja Makarow, EMBC 8

past & present timeline 12 brief history 13 EMBO | EMBC | EMBL 14 EMBO actions 2005 17 EMBC actions 2005 19

EMBO & EMBC programmes and activities fellowship programme 23 courses & workshops programme 24 world activities 25 young investigator programme 26 women in the life sciences 27 science & society programme 28 electronic information programme 29

EMBO activities The EMBO Journal 32 EMBO reports 33 Molecular Systems Biology 34 journal subject categories 35 national science reviews 36 gold medal 37 award for communication in the life sciences 38 sectoral meetings 39 plenary lectures 40 communications offi ce 41 European Life Sciences Forum (ELSF) 42

➔ 2 table of contents

appendix EMBC delegates and advisers 46 EMBC scale of contributions 53 EMBO council members 2005 54 EMBO committee members & auditors 2005 55 EMBO council members 2006 56 EMBO committee members & auditors 2006 57 EMBO members elected in 2005 58 advisory editorial boards & senior editors 2005 66 long-term fellowship awards 2005 70 long-term fellowships: statistics 84 long-term fellowships 2005: geographical distribution 86 short-term fellowship awards 2005 88 short-term fellowships: statistics 102 short-term fellowships 2005: geographical distribution 104 young investigators 2005 106 young investigators 2000 – 2004 107 young investigators: statistics 108 young investigator lectures 2005 110 courses | workshops | conferences | symposia 2005 112 plenary lectures 2005 118 participation of women in EMBO activities: statistics 120 EMBO staff 124 events in 2006 courses | workshops | conferences | conference series | symposia 2006 128 plenary lectures 2006 134 other EMBO events 2006 136 organisations and acronyms 138

➔ 3 preface EMBO & EMBC 2005

An awkward time warp surrounds annual 1200 applications for long-term fellowships and reports. The purpose of this type of publication interviewed 600 candidates as part of the selec- is to look back at the activities of the past year. tion process. This kind of input from the EMBO This can be a strange exercise for an organisa- community is a striking demonstration of the ef- tion like EMBO, where the emphasis is on dyna- fectiveness of EMBO as an organisation run by mism and moving forward with initiatives that scientists for scientists and helps us to deliver have a lasting impact on European research. activities that fulfi l the needs of the broader sci- One key benefi t of this retrospective exercise, entifi c community as they arise. Frank Gannon however, is the opportunity to review the over- EMBO journals also continued to play a ma- EMBO Executive Director all impact of events in 2005 and set benchmarks jor role and 2005 saw the launch of Molecular EMBC Secretary General for future activities. Systems Biology as a collaborative venture Taking a single snap-shot of 2005, the over- between EMBO and Nature Publishing Group whelming image is one of increasing demand for (NPG). The fi rst journal to be dedicated solely EMBO activities. EMBO programmes were more to the emerging fi eld of systems biology at the popular in 2005 than ever before. Long-term molecular level, Molecular Systems Biology and short-term fellowship applications were up also represents the fi rst publication by EMBO and requests for funding of EMBO Courses and of a journal along the open-access model. This Workshops increased dramatically. This points electronic journal will work together with the to a growing need and appreciation within the systems biology community to help structure scientifi c community for these activities. this emerging fi eld and to establish guidelines, Participation in EMBO Courses, Workshops standards and metrics for global complex da- and Conferences also reached an all-time high tasets. with more than 5,000 researchers benefi ting In addition to this direct input into research from this high standard of training. Add to this and scientifi c development, EMBO continued to participation in the EMBO Young Investigator extend its infl uence on national and European Programme, other networking activities and Sci- science policy in 2005. In its role as an advisory ence & Society meetings, and the direct impact body to the EMBC Member States, EMBO carried of EMBO on scientists – particularly in Europe – out a major review of the life sciences strategy becomes even more apparent. of the Spanish National Research Council (CSIC), All of this is possible because of the engage- as well as a more detailed assessment of one of ment of the scientifi c community. For example, the largest units of CSIC, the Spanish National in 2005 EMBO Members evaluated more than Biotechnology Centre (CNB). These reviews are

➔ 4 www.embo.org | [email protected] examples of EMBO’s contribution to raising the 2006 and is designed to strategically strengthen standards in science across Europe. research in the EMBC Member States. EMBC A more widely distributed effort, but one in also added to its membership in 2005 with the which EMBO was a lead player, resulted in the formal ratifi cation of the EMBC Agreement by establishment of the European Research Coun- Estonia and acceptance of the Slovak Republic cil (ERC). The Scientifi c Council of the ERC was as a new partner in this truly European consor- selected in 2005, with fi ve EMBO Members and tium. one EMBO Young Investigator contributing to This look in the rear-view mirror shows that the calibre of its membership. Again in the EU EMBO and EMBC have covered many miles in arena, EMBO and ELSF organised a petition for 2005 and that the resulting benefi ts are being greater funding for the framework programme, felt in laboratories all over Europe. The chal- attracting almost 20,000 signatures. 2005 also lenge to maintain this progressive contribution saw EMBO analyse current policy surround- to European research remains and will con- ing the use of animals in research. The results tinue to occupy the EMBO Members, Council, were communicated to the EMBC Delegates management, committees and EMBC such that in a special hearing, maximising the benefi t the 2006 report has even more good news to of this unique linkage between scientists, as convey. represented by EMBO, and policy-makers, as represented by EMBC. A further initiative by EMBC in 2005 was the establishment of a programme of EMBO Installation Grants. This scheme will launch in

www.embo.org | [email protected] ➔ 5 preface EMBO & EMBC 2005

For over 40 years EMBO has promoted Euro- ours in publishing, in programmes that support pean molecular biology. During the last fi ve and encourage younger scientists and in tools of these I have had the privilege to serve as that help scientists in countries that are devel- either Vice-Chair or Chair of the EMBO Council. I oping a modern research infrastructure. leave that duty, no doubt like all Council Chairs After the departure of Iain Mattaj as Execu- before me, convinced that EMBO plays an ab- tive Editor of The EMBO Journal, this important solutely crucial role in the European scientifi c position was fi lled by another EMBL research arena. EMBO is unique in that it was created by scientist, Pernille Rørth. In 2005, Pernille inte- Susan Gasser scientists to serve scientists’ needs. But more grated smoothly into the team and the jour- EMBO Council Chair than that, it is involved in shaping the social nal is doing well under her guidance. Pernille fabric of our continent, as science becomes is supported by a panel of Senior Editors that increasingly relevant to the life of every Euro- includes Tim Hunt, Tony Hunter, Ari Helenius pean citizen. Furthermore, EMBO provides an and David Baulcombe. Given the breadth of The important demonstration of how bottom-up EMBO Journal, this additional input from top sci- administration can be rapidly responsive to the entists from different fi elds is highly benefi cial. ever-changing landscape of social and scientifi c The Senior Editors – who served their fi rst full attitudes and needs. year in 2005 – are helping on judgement calls as EMBO is concerned fi rst and foremost with well as bringing unconventional and insightful its core activities, which are pursued by a dedi- papers into the journal. cated staff that maintains rigorous standards Efforts to expand the links between The while keeping an eye on innovation. In addition, EMBO Journal and EMBO reports were contin- EMBO is constantly forging novel tools to pro- ued in 2005, with the aim of increasing the im- mote science at local, national and international pact of science published in both journals. Each levels – thereby evolving to match new chal- journal’s website now features highlights from lenges. Nothing exemplifi es this better than EM- the other. A further push in this direction has BO’s role in leading the way towards a European resulted in cross-publication of the tables of Research Council, which will unify and extend contents in the print versions of the journals. funding possibilities by providing a new tool for The biggest news on the publishing front competitive awards through EU support. in 2005, however, was the launch of Molecular What has EMBO achieved over the past year? Systems Biology – an open access, electronic Here I recap a few highlights among the EMBO journal developed together with Nature Publish- core activities that have led to novel endeav- ing Group (NPG). Molecular Systems Biology is

➔ 6 www.embo.org | [email protected] led by a panel of Senior Editors with outstand- The Young Investigator Programme is be- ing credentials and a small editorial team at coming increasingly well-known and its net- EMBO. This venture is allowing EMBO to test working activities are much appreciated. The new modes of publishing while simultaneously fact that other organisations are developing exploring the latest fi eld of biological research. their own programmes to honour outstanding, As the fi rst electronic-only molecular systems newly independent scientists indicates how biology journal, Molecular Systems Biology is visionary EMBO’s initiatives were. another indicator of EMBO’s innovation. I leave the EMBO Council in the capable EMBO’s central activities continue to be the hands of Tim Hunt and Erik Boye (Vice-Chair), Fellowship Programme, Courses & Workshops and I am sure that, together with Frank Gannon Programme and Young Investigator Programme. and the entire EMBO staff, they will continue the As proof of their importance we note a continu- remarkable EMBO tradition of delivering what al increase in applications for EMBO Long-Term science and scientists want and need. Fellowships – now reaching over 1200 – and a record number of applications to the EMBO Courses & Workshops Programme.

www.embo.org | [email protected] ➔ 7 preface EMBO & EMBC 2005

The uncertainty of a researcher’s career is one ence that would benefi t their careers. Together, of the major problems in the European Research the two organisations have trained new gen- Area. It has arisen mainly because national and erations of scientists to carry out high-quality international funding instruments are fragment- research with an open mind and a broad skills ed, and universities and many other research base. Most EMBO Fellows return to either their institutions lack a coherent ladder of promotion. home country or another European country In addition, infl exibility can be a major impedi- after their post-docs. However, at this point re- ment to the career path. For example, extramu- searchers are challenged with career path un- Marja Makarow ral competitive funding usually does not provide certainties. EMBC President a salary and thus does not contribute to career EMBC and EMBO approached this problem progression. Also, mobility between public and by creating the EMBO Young Investigator Pro- corporate research organisations is often diffi - gramme in 2000. Annually, this initiative selects cult. about 20 young principal investigators from All in all, the career path of a scientist in approximately 150 high-quality applicants. Al- Europe is highly unpredictable, regardless of a though the fi nancial award, paid mostly by the researcher’s merit. This becomes a burning sci- researcher’s country, is not very high, the “qual- ence policy issue because the less attractive ity label” and promotional activities associated research is as a career, the more often Europe with the award signifi cantly enhance the young loses talent to other parts of the world. investigators’ standing within the scientifi c com- EMBC and EMBO have been working for munity, thereby contributing to their success in many years to make European research in the securing funding. Networking activities are also life sciences attractive and competitive. With a a major benefi t of the programme. Each young founding goal of promoting and improving the investigator is paired with a mentor – typically standard of molecular biology in Europe, EMBO a high profi le EMBO Member – and linked into a has been organising training courses and work- growing international network of young investi- shops since its beginnings, as well as selecting gators. Awardees are also given the opportunity the best young scientists for post-doctoral fel- to participate in courses on laboratory manage- lowships. EMBC was created to secure funding ment and other skills essential for leaders of re- for those activities as their value became recog- search groups, as well as sending members of nised. For decades EMBC and EMBO have been their laboratories to training courses. taking measures to provide young researchers The Young Investigator Programme on its with skills and professional international experi- own is not enough, given the high number of

➔ 8 www.embo.org/embc | [email protected] talented researchers relative to the number of Programme and the Howard Hughes Medical such awards. Also, there is a particularly strong Institute (HHMI), it shows how EMBC and EMBO need for support of independent researchers adapt and develop their activities to match the in countries that are at a developmental stage changing needs of European science. in their life sciences research programmes. As is clear from this annual report, joint ef- Thus, EMBC and EMBO have been working to forts by EMBC and EMBO are bringing about establish another initiative, the EMBO Installa- solutions to problems arising in the European tion Grants. Under this scheme, EMBC Member Research Area. Obviously, more answers to new States in a development phase with regard to questions will be required as the area evolves, molecular biology research can allocate funds and EMBC will continue to bring together gov- for researchers, who wish to return or move to ernmental representatives and leading scien- these countries to establish their own laborato- tists to effect government funding of initiatives ries. EMBO’s role will be to provide expert as- in support of science. Hopefully, EMBC actions sistance in choosing the awardees. The found- will have a lasting impact on the scientifi c com- ing countries of this initiative will be Croatia, the munity such that a research career in Europe is Czech Republic, Estonia, Poland, Portugal and viewed as an attractive and fulfi lling option for Turkey. As this activity grows from an earlier bright young people. joint initiative between the Young Investigator

www.embo.org/embc | [email protected] ➔ 9 PAST & PRESENT EMBO EMBC EMBL EMBO | EMBC past & present

timeline & brief history page 12–13

aims EMBO | EMBC | EMBL page 14–16

EMBO actions 2005 page 17–18

EMBC actions 2005 page 19

➔ 11 EMBO timeline

1964 1966 1970 1974 1976 1986 1994 1996 1998 2000 2002 2004

1963 19651969 1973 1975 1981 1991 1995 1997 1999 2001 2003 2005

1963 Election of first EMBO officers 1986 EMBO Gold Medal launched 2001 EMBO moves to new building

1964 EMBO incorporated as 1991 EMBO East European Fellowships 2002 EMBO Restart Fellowships a non-profit organisation established (discontinued in 1994) initiated (integrated into long-term and appoints 200 members fellowship scheme in 2004); 1994 Frank Gannon appointed EMBO Award for Communication 1965 Raymond Appleyard appointed Executive Director of EMBO in the Life Sciences launched Executive Secretary of EMBO 1995 Review of Austrian Molecular 2003 Review of 1966 Funding for nine long-term and Biology Programme French Genopole System 22 short-term fellowships and the first three practical courses 1996 EMBO Lectures and EMBO 2004 EMBO Life Sciences Mobility Portal secured by the Volkswagen Members Workshop established; and E-BioSci go live; Stiftung EMBO Fellows Network started; Initiative for Science in Europe Science & Society activities (ISE) established in conjunction 1969 Governments of 14 member initiated with other organisations states establish the European Molecular Biology Conference 1997 Review of Finland 2005 EMBO Conference Series – (EMBC) Biotechnology Programme first call for applications; Award of EMBO/HHMI Startup Grants 1970 Formal ratification of EMBC 1998 European Biotechnology Node in support of research in Central for Interaction with China (EBNIC) Europe; 1973 John Tooze appointed established under EMBO EMBO and Nature Publishing Group Executive Secretary of EMBO co-ordination launch Molecular Systems Biology journal; 1974 EMBL established by EMBC 1999 Sectoral meetings started; Reviews of CNB and life sciences Review of Hungarian biology strategy of Spanish National Research 1975 EMBO Annual Symposium Council (CSIC) (discontinued 1994) 2000 EMBO reports launched; E-BioSci, Young Investigator Programme 1976 Statement from EMBO on and World Programme recombinant DNA technology initiated (integrated across several EMBO programmes in 2004); 1981 The EMBO Journal launched ELSF established in conjunction with other organisations

➔ 12 brief history

History The origins of EMBO date back to 1963, when a The EMBO Council worked hard to secure group of leading European biologists gathered long-term funding for EMBO activities and in in Ravello, Italy to discuss proposals by John 1969 the governments of 14 member states Kendrew and Conrad Waddington to establish came together to establish the European Mo- a laboratory and an organisation to promote co- lecular Biology Conference (EMBC). The formal operation in molecular biology. Both proposals ratifi cation of this intergovernmental organisa- were endorsed at this meeting and later, in July tion followed in 1970. EMBC adopted the activi- 1964, the European Molecular Biology Organiza- ties initiated with the Volkswagen funding and tion (EMBO) was offi cially born. these became known as the EMBC General Pro- The Ravello meeting laid down two initial gramme. Soon after its foundation, EMBC also goals for EMBO – the creation of a central mo- accepted a proposal by EMBO to establish a lecular biology laboratory and the establishment European laboratory. As a result, ten of the of networking activities to enhance interactions EMBC Member States came together in 1974 to between European laboratories. To pursue form EMBL as an independent intergovernmen- these goals, two committees were set up: the tal organisation. Laboratory Committee, whose efforts led to the Today EMBC has grown to 25 member states subsequent establishment of the European Mo- including most of the European Union (EU) and lecular Biology Laboratory (EMBL); and the Fed- some neighbouring countries. eral Organisation Committee, which became the motor for the EMBO Courses & Workshops Programme and the Fellowship Programme. The Ravello meeting also saw the election of Max Perutz as the fi rst EMBO Chairman and John Kendrew as Secretary General. Thanks to the efforts of the late Eduard Kellenberger, one of EMBO’s founding members, EMBO was awarded offi cial legal status on 12 July 1964. Start-up funding for the organisa- tion was generously provided by the Volkswa- gen Foundation and enabled EMBO to get its fi rst networking activities underway, providing fellowships and practical courses. EMBO also elected 200 biologists as its fi rst members.

www.embo.org/about_embo/history.html ➔ 13 aims EMBO | EMBC | EMBL

EMBO EMBO works with leading researchers to pro- EMBO also supports the scientifi c com- mote excellence in the molecular life sciences munity through its journals. The EMBO Journal in Europe. The organisation supports transna- and EMBO reports are already well established tional mobility, training and exchange at all in the scientifi c literature. The newest journal, stages of the scientifi c career through a number Molecular Systems Biology, is a unique venture of programmes and initiatives. These fall into for EMBO in that it is solely electronic and based two distinct categories: those that make up the on an open-access business model. The journal EMBC-funded General Programme, and those was launched in March 2005 and is the fi rst on- that are initiated and developed independently line publication to be dedicated to the emerging by EMBO. fi eld of molecular systems biology. The EMBC General Programme includes The backbone of all EMBO activities is its well-known activities such as fellowships for membership. EMBO elects new members an- long-term and short-term laboratory visits, the nually on the basis of proven excellence in re- funding of practical courses and workshops, search. Today, EMBO has over 1200 members in and activities highlighting young independent Europe and over 60 associate members world- researchers of high quality. In addition, EMBC wide, providing a dedicated focal point for the supports activities that foster an open dialogue vast network of molecular biology. EMBO Mem- between scientists and non-scientists, as well bers are some of the leading researchers in as web-based services for EMBO’s programmes Europe, amongst them 38 Nobel laureates. The and communities. members provide valuable input to EMBO in all In recent years, EMBO has pursued a strat- of its activities and formally through their par- egy of analysing European science and devel- ticipation in various EMBO committees. oping new activities to meet the needs of the EMBO activities are delivered by a dedicated molecular biology community. EMBO pilots team of managers, administrators and editors and funds these new actions to determine the at the EMBO headquarters in Heidelberg (see potential benefi t of adding them to the more page 126). The EMBO Council is also intensely permanent EMBC programme. The funding of engaged in EMBO actions and contributes de- such activities comes predominantly from the cisively to the direction of the organisation by scientifi c journals EMBO publishes. Support is providing input on scientifi c standards and poli- also procured in the form of grants, particularly cy. The Council regularly examines the range of from the EU or occasionally through collabora- EMBO activities, monitoring their effectiveness tions with international organisations. and making recommendations for changes.

➔ 14 www.embo.org | [email protected] EMBC EMBC is an intergovernmental organisation comprising 25 member states. Founded in 1969 and ratifi ed in 1970, it supports and fi nances the actions of EMBO, bringing quality scientifi c initiatives to Europe. EMBC promotes a strong pan-European approach to research and its membership includes most of the EU as well as some neighbouring countries (see table). EMBC supports a wide range of EMBO ac- tivities as part of its General Programme. Long- standing initiatives such as the EMBO Fellow- ship Programme and the Courses & Workshops Programme still constitute the main focus of EMBC. In more recent years, the EMBC scope has expanded to include the Young Investigator Programme, Electronic Information Programme and Science & Society Programme. EMBC Member States EMBC and EMBO operate in harmony and The following countries make up the European Molecular Biology Conference (EMBC): are driven by a common commitment to quality research at the pan-European level. The actions ➔ Austria ➔ Estonia* ➔ Hungary ➔ The Netherlands ➔ Spain of both organisations are characterised by se- ➔ Belgium ➔ Finland ➔ Iceland ➔ Norway ➔ Sweden lection on the grounds of quality and strong co- ➔ Croatia ➔ France ➔ Ireland ➔ Poland ➔ Switzerland operation with the scientifi c community. EMBC ➔ Czech Republic ➔ Germany ➔ Israel ➔ Portugal ➔ Turkey has decision-making power over the funding ➔ Denmark ➔ Greece ➔ Italy ➔ Slovenia ➔ United Kingdom and development of all EMBO activities associ- ated with the EMBC General Programme, while EMBC membership applications from Luxembourg and the Slovak Republic have been accepted EMBO has full responsibility for the delivery of and are awaiting formal ratifi cation. Special provisions also exist for Cyprus. these activities. The actions of EMBO are moni- tored and the overall programme is decided by *Formal ratifi cation of the EMBC Agreement took place in January 2006. the EMBC Delegates when they meet annually in conference. ➔ For the scale of contributions by individual EMBC Member States see page 53

www.embo.org/embc | [email protected] ➔ 15 aims EMBO | EMBC | EMBL

EMBL The creation of a central molecular biology labo- and visitors; to develop new instrumentation for ratory was one of the founding goals of EMBO. biological research; and to transfer the benefi ts An EMBC Special Project and early efforts by of new discoveries and technologies to society. the EMBO Council resulted in the establishment Today these core functions are complemented of EMBL. In 1974 EMBL became an independent by outreach activities in the areas of science entity supported by a subset of EMBC Member and society and training for science teachers. States. Today 18 of the EMBC Member States EMBL is independent from EMBC and EMBO, are also member countries of EMBL. but all three act in a mutually supportive man- EMBL has fi ve core missions: to conduct basic ner, both at a strategic and practical level. Full research in molecular biology; to provide essen- details of EMBL activities can be found on the tial services to scientists in its member states; laboratory’s website at www.embl.org or in the to provide high-level training to staff, students EMBL Annual Report.

Aerial view of EMBO and EMBL Heidelberg in Germany. The EMBC administration is also located in the EMBO building.

➔ 16 www.embl.org EMBO actions 2005

The EMBO Council met in Heidelberg on 4 – 5 from application documents. The aim is to com- EMBO offi cers for 2005 October 2005. The decisions from this meeting pare the results with data from previous years Susan Gasser are listed below, along with upcoming decisions to establish whether gender has any impact on Chair, EMBO Council and the outcomes of other EMBO activities. selection. Erik Boye Vice-Chair, EMBO Council ➔ As of 2006 EMBO will contribute 100,000 Christiane Nüsslein-Volhard Offi cer, committee euro toward the provision of child-care support EMBO Secretary General and membership elections for female fellows with pre-school children. ➔ Susan Gasser fi nished her term as Chair Maria Leptin of EMBO Council at the end of 2005 and is ➔ It was decided that EMBO will phase out its Chair, EMBO Membership Committee replaced by Tim Hunt in 2006. Erik Boye was re- involvement in its literature and gene search Daniela Rhodes elected Vice-Chair. engine, E-BioSci (see page 29). Chair, EMBO Fellowship Committee Pico Caroni ➔ Benny Shilo was newly elected to the Strategy analysis Chair, EMBO Course Committee EMBO Council for 2006 – 2008. For this period, ➔ The EMBO Council and EMBC will meet in Regine Kahmann Margaret Buckingham and Maciej Zylicz˙ were April 2006 to analyse interactions between the Chair, re-elected, and Marjori Matzke and David Shore two organisations. EMBO Young Investigator Committee co-opted. Complete lists of the 2005 and 2006 Roberto Sitia members of the EMBO Council can be found on ➔ A special meeting of the EMBO Council and Chair, pages 54 – 57. the EMBO management will be held in Zurich EMBO Science & Society Committee in March 2006. The focus of this meeting will ➔ Complete lists of the 2005 and 2006 mem- be the future strategy of EMBO, with a concrete Eric Westhof Chair, EMBO Publications & bers of EMBO committees can be found on analysis of where EMBO should be in 2015. Electronic Information Committee pages 54 – 57.

➔ The EMBO Members and Associate Members elected in 2005 are listed on page 58 – 65.

Programme activities ➔ Council accepted a proposal by the EMBO Fellowship Committee to assess all 2006 appli- Tim Hunt replaces Susan Gasser cations in a gender-neutral manner. This means as Chair of the EMBO Council as of that all reference to gender will be removed January 2006.

www.embo.org | [email protected] ➔ 17 EMBO actions 2005

Other EMBO activities: Bernhard Huber and Awards Members survey Bärbel Traut-Laur ➔ Dario Alessi of the University of Dundee, Scot- ➔ A comprehensive online survey of the EMBO are responsible for EMBO’s land won the 2005 EMBO Gold Medal for his Members was carried out in autumn 2005. fi nances. work on cell signalling (see page 37). Approximately 33 percent of the EMBO Mem- bers responded and the data collected revealed ➔ Edwin Rydberg from the IRBM P. Angeletti in a high level of satisfaction with the organisa- Rome, Italy won the EMBO Science Writing Prize. tion. As of 2006, this award will be fused with a simi- Claudia Hagedorn lar EMBL writing prize. National science reviews is the administrator for ➔ In 2005 EMBO carried out two reviews of na- the EMBO membership Meetings tional science programmes (see page 36). The and EMBO Council. ➔ The annual EMBO Members Workshop was fi rst assessed the Spanish National Biotechnol- held in October 2005 in Warsaw, Poland. The ogy Centre (CNB) in Madrid, one of the largest meeting featured a mini-symposium on “Micro- units of the Spanish National Research Council biology Today” and an EMBO Nobel Lecture (CSIC). This was followed by a broader, more given by EMBO Member, Werner Arber. strategic review of CSIC life sciences institutes.

➔ A follow-up neurobiology sectoral meeting also took place in October 2005, at the Insti- tute of Neuroscience (INA) in Alicante, Spain. The meeting brought together more than 100 neurobiologists from the EMBO community and local institutes (see page 39).

European Research Council (ERC) ➔ In May 2005 EMBO submitted a list of mem- bers for consideration to the ERC Identifi cation Committee. These names were put forward after initial consultation with the EMBO Council and further nominations by the EMBO member- ship. Five EMBO Members and one EMBO Young Investigator were ultimately appointed to the ERC Scientifi c Council.

➔ 18 www.embo.org | [email protected] EMBC actions 2005

In 2005 two formal sessions of EMBC took place ➔ The application from the Republic of South EMBC offi cers for 2005 in Heidelberg. In addition, the EMBC Strategic Africa for co-operative status was positively re- Marja Makarow (Finland) Working Party met on two occasions and there ceived and a “Protocol of co-operation” was ac- President was one meeting of the Financial Advisory cepted. Formal ratifi cation will follow in 2006. Krešimir Pavelic´ (Croatia) Group. The decisions resulting from these meet- Peter Weisbeek (Netherlands) ings are listed below. ➔ It was decided that any country accepted for Vice-Presidents membership by EMBC would be given a limit of Frank Gannon (EMBO) 18 months to sign the EMBC Agreement. Secretary General Financial matters ➔ The accounts for 2004 were accepted and Interactions with other organisations Brita Beije (Sweden) Chair, Financial Advisory Group the reports of the external and internal auditors ➔ A plan of action for the co-ordination of strat- were noted. egies between EMBO, EMBL, EMBC and the Maria Jose Almeida (Portugal) EMBL Council was put into place. This includes Vice-Chair, Financial Advisory Group ➔ The Cost Variation Index (CVI) for 2006 was ap- a joint session of EMBC and the EMBL Council, All offi cers were re-elected for proved and the budget for 2006 agreed upon. to be held in July 2006. the year 2006.

➔ The fi nancial rules were amended to defi ne ➔ The request from EMBC to receive advice ➔ For a list of all EMBC Delegates the membership of the EMBC Audit Committee from EMBO on science policy was acted upon, and Advisers see pages 46 – 52 as follows: Chair, Vice-Chair and representatives with a special hearing on the use of animals in from Finland, France, Germany, Italy, Poland, research taking place prior to the formal EMBC Spain, Switzerland and the United Kingdom. meeting in November 2005. This initiative will Strategic Working Party members be continued in November 2006, with a similar Ahmet Ademoglu (Turkey) New initiatives input of expert advice on the topic of stem cells. Brita Beije (Sweden) ➔ An EMBC Special Project supporting EMBO Isabella Beretta (Switzerland) Installation Grants was established. The new EMBC also continued its series of special work- Eckhart Curtius (Germany) funding scheme aims to strengthen the scien- shops in 2005. These workshops bring together Bernard Ehresmann (France) tifi c infrastructure in particular EMBC Member key stakeholders from the research infrastruc- Frank Gannon (EMBO) States. The scheme will be announced offi cially tures of particular member states – providing a Marja Makarow Chair (Finland) early in 2006. discussion forum for the role EMBC/EMBO plays Juan Modolell (Spain) in promoting basic research within that country Krešimir Pavelic´ (Croatia) Membership issues and across Europe as a whole. Two workshops Glauco Tocchini-Valentini (Italy) ➔ The application from the Slovak Republic for took place in 2005, the fi rst in Berlin, Germany Peter Weisbeek (Netherlands) EMBC membership was accepted. and the second in London, United Kingdom. Douglas Yarrow (United Kingdom)

www.embc.org | [email protected] ➔ 19 EMBO title

EMBO & EMBC PROGRAMMES & ACTIVITIES 2005

➔ 20 www.embo.org | [email protected] EMBO | EMBC programmes and activities

fellowship programme page 23

courses & workshops programme page 24

world activities page 25

young investigator programme page 26

women in the life sciences page 27

science & society programme page 28

electronic information programme page 29

➔ 21 ➔ 22 fellowship programme

The EMBO Fellowship Programme is renowned for its attention to scientifi c excellence Jan Taplick with a rigorous selection process involving EMBO Members. EMBO Fellowships have fund- Programme Manager ed thousands of talented young scientists since the programme was established in the 1960s. These awards facilitate movement between EMBC Member States and also between non-member states and member states for research visits of varying duration. Liselott Maidment Administrator, ➔ Long-term fellowships support post-doctoral ➔ The EMBO Fellows Network keeps long-term long-term fellowships scientists, usually for a period of two years. fellows in touch with one another and abreast of developments at EMBO. By linking these Agnès Visser-de Matteïs ➔ Short-term fellowships support collaborative promising young scientists with the broader Administrator, research visits for a period of up to three months, EMBO community, the network fosters a sense short-term fellowships thereby allowing scientists to complement their of community and collaboration – providing research at home with new techniques. a focal point for the fellows as they progress through their careers. ➔ The annual EMBO Fellows Meeting brings to- gether long-term fellows in the fi nal year of their 2005 HIGHLIGHTS fellowship. The young scientists have the oppor- ➔ EMBO Long-Term Fellowships tunity to present the results of their research 1236 applicants /198 awards projects, learn about career opportunities and (16 % success rate) share their international experiences. ➔ EMBO Short-Term Fellowships ➔ The biennial North American meeting keeps 383 applicants / 201 awards current and former long-term fellows now (52 % success rate) working in Canada and the USA up to date with developments in Europe. The meeting features ➔ EMBO Fellows Meeting scientifi c presentations by other members of Heidelberg, Germany (72 participants) the EMBO community as well as by representa- tives of various funding organisations. The next ➔ For long-term fellowship trends and statistics see pages 70 – 87 meeting is in San Diego in November 2006. ➔ For short-term fellowship trends and statistics see pages 88 –105

www.embo.org/fellowships | [email protected] ➔ 23 EMBO courses & workshops programme

Mary Gannon The EMBO Courses & Workshops Programme has been facilitating scientifi c training and Programme Manager exchange throughout Europe since the founding of EMBO. The programme funds several types of meetings, providing quality training to scientists at all career levels and covering a wide range of topics in molecular biology. Zeynep Dinsi-Yararli Administrator ➔ Practical courses teach cutting-edge tech- ➔ Symposia are based on interdisciplinarity and niques to groups of up to 20 scientists, mainly are co-sponsored with other scientifi c organisa- from European laboratories. tions, currently the European Science Founda- Lynne Turnbull tion (ESF). Administrator, ➔ Lecture courses provide up to 100 students Online HelpDesk with up-to-date information on a range of 2005 HIGHLIGHTS ➔ diverse topics. EMBO Practical Courses 22 applications / 20 funded ➔ Workshops bring together approximately 120 973 applicants / 409 participants Departures scientists from related yet distinct fi elds and Kathy Oswald ➔ EMBO Lecture Courses foster high-level discussion on topics of com- Felise Fortmann 9 applications / 5 funded mon interest. Administrators 670 applicants / 375 participants

➔ Conferences cater for larger groups, focusing ➔ EMBO Workshops on topical scientifi c issues and fostering col- 32 applications / 20 funded laboration. 2277 applicants / 1995 participants

➔ Conference series support and strengthen ➔ EMBO Conferences European scientifi c communities by guarantee- 10 applications / 8 funded ing funding for a series of three conferences 2283 applicants / 2130 participants over a six-year period, alternating with cor- responding meetings in the USA. Application ➔ ESF-EMBO Symposia opened in 2005 and the fi rst meetings to be 4 applications / 3 funded sponsored will take place in 2006. 364 applicants / 266 participants

➔ For a complete list of 2005 courses and workshops see pages 112 –117 ➔ For a complete list of courses and workshops planned for 2006 see pages 128 –133

➔ 24 www.embo.org/courses_workshops | [email protected] world activities

In recent years, EMBO has made concerted efforts to raise its profi le beyond Europe, par- ticularly in countries with less established scientifi c infrastructures. EMBO World Activities have become an integral part of many EMBO programmes with the aim of attracting prom- ising applicants from outside Europe and promoting international collaboration.

➔ The Courses & Workshops Programme funds 2005 HIGHLIGHTS international courses, workshops and plenary ➔ EMBO Practical Courses (World) lectures that take place outside Europe. 13 applications / 9 funded 423 applicants / 197 participants ➔ The Fellowship Programme has extended its eligibility criteria for short-term fellowships to ➔ EMBO Workshops (World) encourage applications from outside Europe 3 applications / 3 funded and to promote international exchange (see 245 applicants / 210 participants page 23). ➔ Fellowship applications from outside Europe ➔ The Life Sciences Mobility Portal (see page 29) 24 applicants / 15 awards (63 % success rate) has been extended to provide information on European funding sources and grant applica- tion procedures to interested scientists from outside Europe.

➔ For a list of 2005 courses and workshops held outside Europe see pages 113 – 116 ➔ For a list of courses outside Europe planned for 2006 see pages 129 – 130

www.embo.org/world | [email protected] ➔ 25 EMBO young investigator programme

Gerlind Wallon The EMBO Young Investigator Programme supports and promotes outstanding scientists Programme Manager in Europe during the early years of their independent careers. Awardees join a growing network that currently links over 170 scientists in 22 EMBC Member States. The benefi ts offered by the programme raise the young investigators’ profi les in the scientifi c com- Kim Krynauw munity and provide unique training opportunities. In 2005 a co-operation with the Howard Administrator Hughes Medical Institute (HHMI) also offered support to scientists setting up their fi rst laboratories in Central Europe.

➔ Networking activities include an annual The EMBO Young Investigators also receive a meeting of the EMBO Young Investigators, ex- free subscription to EMBO reports and free on- changes between their laboratories, the annual line access to The EMBO Journal. EMBO Members Workshop and a mentorship programme involving the EMBO membership. 2005 HIGHLIGHTS ➔ EMBO Young Investigator awards ➔ Promotion of individual scientists is sup- 128 applicants / 17 awards (13 % success rate) ported by sponsorship of young investigator ➔ EMBO/HHMI Startup Grants lectures at international meetings, publication 39 applicants / 6 awards (15 % success rate) of a promotional brochure highlighting the sci- entists’ research and an invitation to write a ➔ 5th EMBO Young Investigator Meeting review for EMBO reports. Heidelberg, Germany (54 participants)

➔ 3rd EMBO Young Investigator Programme ➔ Training opportunities include laboratory Symposium “Quantitative Biology” management courses for the young investiga- Heidelberg, Germany (100 participants) tors, an annual PhD course for their students and international symposia on topics chosen by ➔ EMBO Laboratory Management Courses ➔ For a list of young investigators young investigators. Heidelberg, Germany (62 participants, 4 courses) selected in 2005 see page 106 ➔ 4th EMBO Young Investigator PhD Course ➔ Financial support comes in the form of an Heidelberg, Germany (36 participants) ➔ For a list of programme events in 2006 annual 15,000 euro award from the individual see page 136 EMBC Member States. In addition, a total of ➔ EMBO/HHMI Central European 175,000 euro in top-up support is available from Scientists Meeting ➔ For statistics and a list of young inves- EMBO. Budapest, Hungary (132 participants) tigator lectures see pages 107 –111

➔ 26 www.embo.org/yip | [email protected] women in the life sciences

EMBO promotes the highest standards of research throughout its member states at all stages of the scientifi c career. In recent years, EMBO has made efforts to assess and act on imbalances or uncertainties in this career path – examining the potential differences and diffi culties for particular groups including female scientists and all researchers with child-care commitments.

➔ EMBO actively monitors gender balance ➔ EMBO is acutely aware of the low represen- in the life sciences generally and in EMBO- tation of women in senior positions in science sponsored activities, so that the cause of any in spite of equal representation at the gradu- imbalances can be analysed and addressed. ate level. In an effort to improve this particular imbalance, EMBO offers female young investi- ➔ Special conditions are offered to long-term gator candidates with children an extension of fellows with children. These include paid mater- the eligibility period for the award. nity or paternity leave, the option of a part-time work schedule and special restart conditions 2005 HIGHLIGHTS (e. g. waiver of the requirement to move coun- ➔ EMBO/FEBS Workshop on Women in Science try). As of 2006, additional crèche support will be “Creating awareness: Lessons from the MIT study” offered to women with children under six years by Nancy Hopkins (MIT) at annual FEBS Congress, of age. Budapest, Hungary

➔ For statistics see pages 120 –123

www.embo.org/gender | [email protected] ➔ 27 EMBO science & society programme

Andrew Moore The Science & Society Programme supports scientists in their communication with non- Programme Manager scientists, encourages multidisciplinary dialogue with the public and contributes to im- provements in biology education and science policy-making. A diverse range of activities promotes the development and communication of modern biology. Alessandra Bendiscioli Administrator ➔ Multidisciplinary Science & Society Confer- ➔ International workshops on secondary school ences are organised annually in collaboration biology education are an annual forum for bi- with EMBL. ology teachers to update their knowledge and skills, exchange information and meet other ➔ The Award for Communication in the Life teachers and scientists. Sciences is presented annually to a practising life scientist for outstanding communication ➔ Media workshops give young scientists a with the public. chance to learn how the media works and practise communication skills with professional journalists.

➔ The EMBO Science Writing Prize is awarded ➔ For a list of programme events in 2006 see page 137 annually for an innovative and engaging piece of 2005 HIGHLIGHTS writing that communicates science to non-sci- entist readers. In 2006 the prize will be awarded ➔ 6th EMBO/EMBL ➔ 4th EMBO ➔ EMBO jointly with EMBL. Joint Conference on International Science Writing Prize Science & Society Workshop for goes to Edwin Rydberg ➔ A small grants scheme for science and so- “Science and Security” Biology Teachers (see page 18) ciety initiatives helps practising life scientists Heidelberg, Germany Heidelberg, Germany to initiate public communication or outreach 193 participants 125 participants from ➔ Policy activities activities. 24 countries briefi ng paper on ➔ EMBO Award for the use of animals in ➔ Focus meetings on science policy topics bring Communication in ➔ 5th EMBO biomedical research together specialists from different disciplines to the Life Sciences Media Workshop (available on website) produce documents that inform policy-making, goes to Edoardo Boncinelli Heidelberg, Germany covering issues ranging from careers in the life (see page 38) 70 participants sciences to stem cell research.

➔ 28 www.embo.org/scisoc | [email protected] electronic information programme

The Electronic Information Programme was originally initiated to give life science research- Les Grivell ers better access to the scientifi c literature and other relevant digital information. The Programme Manager programme shifted focus in 2005 and now increasingly supports EMBO’s programmes and resulting communities. These include EMBO Members, Fellows, Young Investigators and participants of EMBO Courses and Workshops. Experience gained in the development of Ole Hansen web-based services for E-BioSci, a literature and gene search engine, and the ORIEL infor- Technical Offi cer mation management system has been particularly valuable in these efforts.

➔ Integrated web-based database services are 2005 HIGHLIGHTS Patricia Codyre used by the Fellowship Programme, Courses & ➔ Expansion of Life Sciences Mobility Portal Communications Offi cer Workshops Programme and Young Investigator to provide information on European funding (Web) Programme. sources and grant application procedures to scientists from outside Europe Anne Seller ➔ Online application systems have been devel- Administrator oped for the Courses & Workshops Programme ➔ Increasing number of visitors and its new HelpDesk facility. to the Life Sciences Mobility Portal from Russia, Turkey, Israel and India Sabine ➔ A professional content management system Rehberger-Schneider is run for the EMBO and EMBC websites. ➔ First award made in the Life Sciences Life Sciences Mobility Consultant Mobility Portal’s “Write Move” competition ➔ The Life Sciences Mobility Portal is an online Laura Cortesi search engine that helps young researchers ➔ Re-design of main EMBO website Data Manager pinpoint suitable funding, training and job op- portunities. The database is carefully curated ➔ Successful completion of EU-funded and regularly updated. In addition, a personal E-BioSci and ORIEL projects consultancy service provides individual advice (see page 17) on fi nding transnational funding sources not covered by the portal.

www.embo.org/eip | [email protected] http://mobility.embo.org | [email protected] ➔ 29 EMBO title

EMBO ACTIVITIES 2005

➔ 30 www.embo.org | [email protected] EMBO activities

The EMBO Journal page 32

EMBO reports page 33

Molecular Systems Biology page 34

journal subject categories page 35

national science reviews page 36

gold medal page 37

award for communication in the life sciences page 38

sectoral meetings page 39

plenary lectures page 40

communications offi ce page 41

European Life Sciences Forum (ELSF) page 42

➔ 31 journals The EMBO Journal

The EMBO Journal is a print and online publication that covers all areas of molecular biology (see subject categories on page 35). In 23 years of existence, it has established itself as one of the leading molecular biology journals worldwide – with a current impact factor of 10.492 and a citation half-life of 6.3 years. Pernille Rørth Executive Editor ➔ High editorial standards are ensured by a oping world through the WHO-brokered HINARI Isabel Arnold full-time editorial team based at the EMBO initiative. Karin Dumstrei headquarters and active support from a panel Valerie Ferrier* of Senior Editors and an international Advisory ➔ Full text of articles published prior to 1997 is Thomas Lemberger Editorial Board. now available electronically for the fi rst time via Volker Wiersdorff PubMed Central. Editors ➔ Fast and fair decisions on primary research *(Co-ordinator) articles are made within one week of submis- 2005 HIGHLIGHTS sion for initial editorial decisions and within ➔ Appointment of current Frank Gannon three to four weeks for manuscripts sent out Advisory Editorial Board Associate Editor for in-depth peer review. ➔ First meeting of Jana Christopher ➔ Effi cient processing of submissions is sup- The EMBO Journal Senior Editors Claire Johnstone ported by an online submission system at Fiona Panayi http://mts-emboj.nature.com. ➔ Implementation of “eJournalPress” Karen Thompson online submission system Editorial Assistants ➔ Rapid online publication of articles after acceptance ensures that research results are ➔ The complete archive of The EMBO Journal Departures made available without delay. is available electronically Astrid Lunkes Editor ➔ Wide exposure of articles is achieved by high- Senior Editors Sophia Katsogiannos lighting across Nature Publishing Group’s sub- David C. Baulcombe Editorial Assistant ject area pages and gateways. Ari Helenius Tim Hunt ➔ Free online access is available to all read- Tony Hunter ers after 12 months via both nature.com and ➔ For a list of Advisory Editorial Board members PubMed Central, and immediately to the devel- see pages 66 – 67

➔ 32 www.embojournal.org | [email protected] EMBO reports

EMBO reports blends primary research papers, reviews, meeting and literature reports Frank Gannon with quality journalism to provide molecular biologists with a wide range of information Senior Editor and perspectives on their research. The journal covers all areas of molecular biology (see subject categories on page 35) and its current impact factor is 7.567. Holger Breithaupt ➔ High editorial standards are ensured by a full- oping world through the WHO-brokered HINARI Editor, Science & Society time editorial team based at the EMBO head- initiative. quarters and active support from an interna- tional Advisory Editorial Board shared with The 2005 HIGHLIGHTS Susan R. Owens EMBO Journal. ➔ Appointment of current Editor, Reviews Advisory Editorial Board ➔ Additional editorial and graphics support adds value to the content published in the Science & ➔ Science & Society special issue Sandra Caldeira Society and Reviews sections of the journal. “Time & Ageing: Mechanisms and Meanings” Editor, Scientifi c Reports

➔ Fast and fair decisions on primary research ➔ Review series papers are made within one week of submis- “Cycles” Caroline Hadley sion for the initial editorial decision and within Assistant Editor three to four weeks for manuscripts sent out for ➔ Preparations for new “eJournalPress” (Co-ordinator) in-depth peer review. online submission system to be implemented beginning of 2006 Les Grivell ➔ Effi cient processing of submissions and rapid Associate Editor online publication ensure that research results ➔ For a list of Advisory Editorial Board members are made available without delay. see pages 66 – 67 Uta Mackensen ➔ Wide exposure of articles is achieved through Graphics Editor highlights across Nature Publishing Group’s subject area pages and gateways. Departure Caroline Simpson ➔ Free online access is available to all read- Christine M. Blaumueller Editorial Assistant ers after 12 months via both nature.com and Editor, Scientifi c Reports PubMed Central, and immediately to the devel-

www.emboreports.org | [email protected] ➔ 33 journals Molecular Systems Biology

Thomas Lemberger Molecular Systems Biology is an open-access, electronic journal that was jointly launched Editor by EMBO and Nature Publishing Group (NPG) in 2005. Molecular Systems Biology pro- vides a new and unique forum for the publication of papers describing the properties and behaviour of complex biological systems in terms of molecular components and their inter- Les Grivell actions (see subject categories on page 35). Associate Editor ➔ Immediate free access to all content is avail- ➔ Wide exposure of articles is achieved through able through nature.com. highlights across NPG’s subject area pages and Frank Gannon gateways. Associate Editor ➔ High editorial standards are ensured by a full- time editorial team based at the EMBO head- 2005 HIGHLIGHTS quarters and active support by a panel of Senior ➔ Molecular Systems Biology goes live Jana Christopher Editors and an Advisory Editorial Board (see Editorial Assistant page 67) consisting of leading systems biology ➔ “Inaugural Collection” of key papers researchers. 20,000 copies distributed along with issues of major Nature titles Caroline Simpson ➔ A discussion platform on current topics in Editorial Assistant the rapidly evolving fi eld of systems biology is ➔ Journal accepted for inclusion in PubMed provided by reviews, news & views articles and editorials. Departure Astrid Lunkes ➔ Editorial innovation includes the presenta- Editor tion of research articles in a variety of clear and accessible formats, as well as short synopses revealing the signifi cance of the research in a Senior Editors succinct manner. Rudi Aebersold Peer Bork ➔ Technical innovation in the form of enhanced George Church support for structured data formats such as Leroy Hood Systems Biology Markup Language (SBML) max- Edison Liu imises the presentation of systems biology con- ➔ For a list of Advisory Editorial Board members cepts. see page 67

➔ 34 www.molecularsystemsbiology.com | [email protected] journal subject categories

Subject categories representing the scope of The EMBO Journal, EMBO reports and Molecular Systems Biology ➔ Structural Biology ➔ Development ➔ Membranes & Transport ➔ Differentiation & Death ➔ Cell & Tissue Architecture ➔ Cellular Metabolism ➔ Signal Transduction ➔ Neuroscience ➔ Chromatin & Transcription ➔ Immunology ➔ RNA ➔ Microbiology & Pathogens ➔ Proteins ➔ Molecular Biology of Disease ➔ Cell Cycle ➔ Genomic & Computational Biology ➔ Genome Stability & Dynamics

Categories unique to Molecular Systems Biology ➔ Bioinformatics ➔ Metabolic & Regulatory Networks ➔ Proteomics ➔ Synthetic Biology ➔ Functional Genomics ➔ Computational Methods ➔ Structural Genomics ➔ Simulation & Data Analysis

➔ For a list of selected papers published in 2005 see pages 68 – 69

➔ 35 EMBO national science reviews

Panel members: Since 1994 EMBO has offered its services as an advisory and review body to the EMBC Review of CNB Member States. EMBO has carried out reviews of several national research programmes Paolo Costantino (see below). In each case, it has appointed an expert panel of EMBO Members to analyse Stephen Cusack the strengths and weaknesses of the individual life sciences programmes and delivered Gert Groot a report to the national research councils or ministries. Two reviews were carried out in Jörg Hacker 2005. Carl-Henrik Heldin Francesco Sinigaglia ➔ The Spanish National Biotechnology Centre ➔ A broader, more strategic look at CSIC life Anna Tramontano (CNB) in Madrid is one of the largest units of sciences institutes was also undertaken with Detlef Weigel the Spanish National Research Council (CSIC) the aim of gathering an overall impression of Robin Weiss and was assessed in March 2005. The conclu- the collective CSIC strategy in the life sciences. Moshe Yaniv (Chair) sions of the review panel, chaired by Moshe The review panel, chaired by Walter Neupert, Yaniv, were extremely positive and placed CNB provided a general analysis of the plans of Review of CSIC research at the forefront of European science. the different institutes and made a number of life sciences institutes In the context of the report, the panel was able suggestions of general relevance to the CSIC. Adriano Aguzzi to make some recommendations toward fi ne- Andrea Ballabio tuning of the CNB’s research programme. August Boeck Riccardo Cortese EMBO national science reviews Barbara Ensoli 1995 Austrian Molecular Biology Programme Frank Gannon 1997 Finland Biotechnology Programme Nicholas Hastie 1999 Hungarian Academy of Sciences (Life Science Centres) Dirk Inzé 2003 French Genopole System Elisabeth Knust 2005 Spanish National Biotechnology Centre (CNB) Werner Kuehlbrandt 2005 Spanish National Research Council (CSIC) Christopher Leaver Alexander Levitzki Walter Neupert (Chair) Paola Ricciardi-Castagnoli Martin Schwab Bertrand Séraphin Kenneth Timmis Joël Vandekerckhove

➔ 36 www.embo.org/about_embo/reviews.html | [email protected] gold medal

The EMBO Gold Medal is awarded annually to an outstanding young scientist for excep- tional research carried out within Europe. The prize highlights the standards being reached in molecular biology in Europe – bringing the very best young researchers to the attention of a global audience.

The 2005 winner of the EMBO Gold Medal was diabetes, cancer and hypertension. In particular, Dario Alessi of Dundee University’s Medical Re- his discovery and characterisation of PDK1 and search Council (MRC) Protein Phosphorylation LKB1 hold great promise for the treatment of Unit in Scotland. The researcher was honoured inherited diseases. The EMBO Gold Medal was in recognition of his landmark work on kinases presented by the Polish Minister of Science on and their role in disease, which has provided 16 October at Warsaw Royal Castle during the exciting new insights into conditions such as EMBO Members Workshop.

Winners of the EMBO Gold Medal 1986 John Tooze (Heidelberg, DE) 1997 Dirk Görlich (Heidelberg, DE) 1987 Barbara Pearse (Cambridge, UK) 1998 Adriano Aguzzi (Zurich, CH) 1988 Antonio Lanzavecchia (Basel, CH) 1999 Konrad Basler (Zurich, CH) 1989 Hugh Pelham (Cambridge, UK) 2000 Christof Niehrs (Heidelberg, DE) & 1990 Erwin Wagner (Vienna, AT) Daniel St. Johnston (Cambridge, UK) 1991 Patrick Stragier (Paris, FR) 2001 Matthew Freeman (Cambridge, UK) 1992 Carl-Hendrik Heldin (Uppsala, SE) 2002 Amanda Fisher (London, UK) 1993 Jim Smith (London, UK) 2003 Anthony Hyman (Dresden, DE) 1994 Paolo Sassone-Corsi (Strasbourg, FR) 2004 María Blasco (Madrid, ES) 1995 Richard Treisman (London, UK) 2005 Dario Alessi (Dundee, UK) 1996 Enrico Coen (Norwich, UK)

www.embo.org/communities/embo_medal.html | [email protected] ➔ 37 EMBO award for communication in the life sciences

The EMBO Award for Communication in the Life Sciences is presented annually to a practis- ing life scientist in Europe who has made signifi cant contributions to the public communi- cation of science. The award highlights the exceptional efforts made by some individuals to combine science communication activities with a full-time research career.

The winner in 2005 was Edoardo Boncinelli, Pro- Special discretionary award fessor of Biology and Genetics at the University This year, as part of the Award for Communica- Vita-Salute San Raffaele in Milan, Italy. Professor tion, EMBO presented an additional prize for the Boncinelli received the award in recognition of best single initiative in science communication. his longstanding and highly successful efforts in This special award went to Russian scientist, science communication – particularly his ability Dr. Alexander Vershinin, for his outstanding edu- to recognise and explain the social implications cation initiative and innovative book on marine of scientifi c advances. biology, “Life of the Black Sea”. Since 1994, Boncinelli has made topics such as genetics, ageing, neurobiology and public health accessible to a broad audience through popular science books, newspaper articles, TV and radio appearances, participation in public debates and visits to local schools. He received Winners of the EMBO Award for his award on 28 October at the EMBO/EMBL Communication in the Life Sciences Science & Society Conference in Heidelberg, 2002 Ronald Plasterk (Utrecht, NL) Germany. As with past winners, Boncinelli has 2003 Peter Csermely (Budapest, HU) been nominated for the European Commission’s 2004 Fran Balkwill (London, UK) Descartes Prize for Science Communication. 2005 Edoardo Boncinelli (Milan, IT)

➔ 38 www.embo.org/awards/communications.html | [email protected] sectoral meetings

EMBO Sectoral Meetings ensure strong contacts between EMBO and its members in the various areas of molecular biology. The meetings strengthen links between EMBO Mem- bers in similar fi elds and enable EMBO to respond to the different needs and trends in specifi c sectors. Since the initiative was launched in 1999, EMBO has organised Sectoral Meetings in neurobiology, plant biology, microbiology, immunology, molecular medicine and bioinformatics.

The 2005 Sectoral Meeting was a follow-up sions about the representation of neurobiology of the very fi rst meeting, which took place in within the EMBO membership, the impact of 1999 and focused on the topic of neurobiology. EMBO on the future of neurobiology in Europe Locally organised by EMBO Members, Angela and the coverage of neurobiology research in Nieto and Juan Lerma, the meeting took place EMBO’s journals. at the Institute of Neuroscience (INA) in Alicante, Spain. More than 100 participants from the 2005 HIGHLIGHT EMBO community and local institutes discussed ➔ EMBO Sectoral Meeting: Neuroscience the latest developments in the fi eld. In addition Alicante, Spain (102 participants) to excellent scientifi c talks, there were discus-

EMBO Sectoral Meetings 1999 Neurobiology Heidelberg Germany 2000 Plant Biology Heidelberg Germany 2000 Microbiology Heidelberg Germany 2002 Immunology Oeiras Portugal 2003 Molecular Medicine Cavtat Croatia 2004 Bioinformatics & Computational Biology Rome Italy 2004 Molecular Medicine: Leukaemia (follow-up meeting) Staffelstein Germany 2005 Neurobiology (follow-up meeting) Alicante Spain

www.embo.org/communities/groups.html | [email protected] ➔ 39 EMBO plenary lectures

Mary Gannon EMBO has been sponsoring plenary lectures by EMBO Members at major international sci- Programme Manager entifi c meetings since 1999. The programme has a dual purpose – to give EMBO Members the opportunity to intensify exchange and collaboration with scientists from associated Zeynep Dinsi-Yararli fi elds and to bring EMBO activities to the attention of a wider scientifi c audience. Administrator In 2005 EMBO sponsored a total of 25 plenary Departures lectures. 17 were delivered at European events Kathy Oswald and eight EMBO Members brought “The EMBO Felise Fortmann Lecture” to international meetings in countries Administrators as far afi eld as Kenya and Argentina.

In 2005 EMBO Members delivered plenary lectures at major scientifi c meetings in the following countries: In Europe (17 lectures) Outside Europe (8 lectures) Austria Germany Romania Argentina Kenya Croatia Hungary Slovak Republic Australia Mexico Czech Republic Ireland United Kingdom Cuba USA Denmark Italy France Norway

➔ For full details of 2005 plenary lectures see pages 118 –119 ➔ For a list of plenary lectures planned for 2006 see pages 134 – 135

➔ 40 www.embo.org/about_embo/lectures | [email protected] communications offi ce

The EMBO Communications Offi ce serves as an information resource for the scientifi c com- Lindsay Johnson munity, the media and the general public. A number of targeted activities also support an Chief Communications active communication channel between EMBO and its network of members, young inves- Offi cer tigators and fellows. Uta Mackensen ➔ EMBOencounters features the latest news 2005 HIGHLIGHTS Graphic Designer from EMBO and the EMBO community. ➔ Increase in EMBO Member news in EMBOencounters ➔ Brochures, posters, fl yers, and advertise- Anne Seller ments provide clear and consistent information ➔ Online survey of EMBO membership Administrator on EMBO activities. revealed a high rate of satisfaction with EMBO activities and a good readership of ➔ Interaction with the scientifi c community at EMBOencounters major European scientifi c meetings and through regular contact with EMBO Members keeps ➔ Press coverage of EMBO activities scientists informed of developments at EMBO. included a Russian TV broadcast on the EMBO/EMBL Science & Society Conference ➔ Regular communication with the media ensures that the outside world hears about ➔ Strong exhibition presence EMBO developments in a timely manner. at the 2005 meetings of BioScience, FEBS and ELSO

www.embo.org/about_embo/news.html | [email protected] ➔ 41 ELSF European Life Sciences Forum

Luc Van Dyck The European Life Sciences Forum (ELSF) is a platform of organisations representing the Executive Co-ordinator life sciences in Europe. Founded in 2000 by EMBO, the Federation of European Biochemical Societies (FEBS), EMBL and the European Life Scientist Organization (ELSO), its mission is to increase the visibility and impact of the research community in public and policy-making arenas. The secretariat of the ELSF is housed at the EMBO headquarters.

➔ ELSF has been instrumental in establishing 2005 HIGHLIGHTS the multidisciplinary Initiative for Science in ➔ ISE Conference Europe (ISE), whose aim is to structure the ”Celebrating the fi rst concrete steps input of the broad scientifi c community on towards the implementation of the crucial science and technology policy issues in European Research Council (ERC)” Europe. Holding the secretariat of ISE, ELSF now UNESCO, Paris, France provides the impetus for the initiative and co- ordinates its activities. ➔ ISE letter ”Investing in frontier research is ➔ ELSF and ISE actively promote the establish- investing in Europe’s future.” ment of the European Research Council (ERC). sent to Competitiveness Council, Now that the ERC is materialising, ELSF and ISE European Research Commissioner and are monitoring its set-up and providing input European Parliament Committee on Industry, during this crucial stage of its development. Research and Energy (ITRE)

➔ New topics for ELSF and ISE are being devel- ➔ Joint EMBO/ELSF oped and include infrastructure, career devel- petition for increased EU funding opment and ways of promoting science in the in response to an EU proposal for an approximate new EU Member States. 40 % cut in the research budget; over 19,700 signatures were obtained and sent to the EU ➔ ELSF achieves its goals by developing and Heads of State and the research and fi nance maintaining strong relationships with the ministers. European Commission and Parliament.

➔ 42 www.elsf.org | www.initiative-science-europe.org | [email protected]

EMBO title

APPENDIX 2005

➔ 44 www.embo.org | [email protected] appendix

EMBC delegates and advisers pages 46 – 52

EMBC scale of contributions page 53

EMBO council & committees 2005 pages 54 – 55

EMBO council & committees 2006 pages 56 – 57 new members 2005 pages 58 – 65 advisory editorial boards 2005 pages 66 – 67 selected papers from EMBO’s journals 2005 pages 68 – 69 long-term fellowship awards 2005 pages 70 – 83 long-term fellowships: statistics and geographical distribution pages 84 – 87 short-term fellowship awards 2005 pages 88 – 101 short-term fellowships: statistics and geographical distribution pages 102 – 105 young investigators 2005 page 106

EMBO/HHMI Startup Grant recipients 2005 page 106 young investigators 2001 – 2004 page 107 young investigator statistics pages 108 –109 young investigator lectures 2005 pages 110 –111 courses, workshops, lectures, conferences, symposia 2005 pages 112 –117 plenary lectures 2005 pages 118 –119 participation of women in EMBO activities: statistics pages 120 –123

EMBO staff pages 124 –125

➔ 45 EMBC delegates and advisers (as of January 2006)

➔ AUSTRIA Prof. Annemarie Frischauf Dept. of Molecular Biology Hellbrunnerstrasse 34 tel +43 662 8044 5779 [email protected] University of Salzburg AT-5020 Salzburg fax +43 1 662 8044 144 Mag. Elisabeth Tischelmayer Federal Ministry for Education, Rosengasse 2-6 tel +43 1 53120 7120 [email protected] Science and Culture (BM:BWK) AT-1014 Vienna fax +43 1 53120 81 7120 Referat VI/1a

➔ BELGIUM Ms Nicole Henry Belgian Science Policy Offi ce Rue de la Science 8 tel +32 2 238 3507 [email protected] BE-1040 Brussels fax +32 2 230 5912 Prof. Marc van Montagu Plant Biotechnology Institute K.L. Ledeganckstraat 35 tel +32 9 264 87 27 [email protected] for Developing Countries (IPBO) BE-9000 Gent fax +32 9 264 87 95 Gent University

➔ CROATIA Prof. Krešimir Pavelic´´ Rudjer Boškovic Institute Bijenicka c. 54 tel +385 1 468 0094 [email protected] Division of Molecular Medicine POB 180 fax +385 1 456 1010 HR-10002 Zagreb

➔ CZECH REPUBLIC Ms Irena Krumlová Institute of Chemical Technická 3 tel +420 2 24 355 166 [email protected] Technology Prague (ICT) CZ-166 28 Prague 6 fax + 420 2 24 355 167 Dept. of Biochemistry Prof. Václav Pacesˇ Academy of Sciences Narodni 3 tel +420 2 2422 9610 [email protected] CZ-11720 Prague fax +420 2 2424 0512 Dr Zdena Palková Dept. of Vinicná 5 tel +420 2 2195 1721 [email protected] Genetics and Microbiology CZ-12844 Prague 2 fax +420 2 2195 1729 Charles University

➔ 46 EMBC delegates and advisers (as of January 2006)

➔ DENMARK Prof. Julio E. Celis Institute of Cancer Biology Strandboulevarden 49 tel +45 3525 7363 [email protected] Danish Centre for DK-2100 Copenhagen Ø fax +45 3525 7375 Translational Breast Cancer Ms Mette Müller Danish Research Agency 88 Artillevej tel +45 35 44 63 46 [email protected] DK-2300 Copenhagen S fax +45 32 57 35 43

➔ ESTONIA Prof. Toivo Maimets Dept. of Cell Biology Riia 23b-135 tel +372 737 5028 [email protected] Institute of Molecular and EE-80019 Tartu fax +372 742 0286 Cell Biology University of Tartu Mr Toivo Raim Attaché for Scientifi c Affairs Rue Guimard 11/13 tel +32 2 227 39 10 [email protected] Permanent Representation of BE-1040 Brussels fax +32 2 227 39 25 Estonia to the EU

➔ FINLAND Dr Arja Kallio Director, Research Council for Vilhonvuorenkatu 6 tel +358 9774 88 336 arja.kallio@aka.fi Biosciences & Environment FI-00500 Helsinki fax +358 9774 88 395 Academy of Finland Prof. Marja Makarow Vice-Rector P.O. Box 33 tel +358 9 191 21744 marja.makarow@helsinki.fi (EMBC President) University of Helsinki Yliopistokatu 4 fax +358 9 191 23008 FI-00014 University of Helsinki Prof. Eero Vuorio Chancellor Kanslerinvirasto tel +358 2 333 6100 eero.vuorio@utu.fi University of Turku FI-20014 fax +358 2 333 5011 University of Turku

➔ FRANCE Mr Julien Galabru Ministry of Foreign Affairs 244, bd. Saint-Germain tel +33 1 43 17 82 85 [email protected] Directorate General for FR-75303 Paris 07 SP fax +33 1 43 17 89 37 Scientifi c Cooperation and Research DGCID/DCSU/ROP

www.embo.org/embc | [email protected] ➔ 47 EMBC delegates and advisers (as of January 2006)

➔ GERMANY Mr Eckhart Curtius Federal Ministry of Heinemannstr. 2 tel +49 1888 57 3254 [email protected] Education and Research (BMBF) DE-53175 Bonn fax +49 1888 57 8 3254 Referat 613 Ms Paula Heppner Federal Ministry of Heinemannstr. 2 tel +49 1888 57 3653 [email protected] Education and Research (BMBF) DE-53175 Bonn fax +49 1888 57 83653 Referat 613 Prof. Reinhard Lührmann MPI for Biophysical Chemistry Am Faßberg 11 tel +49 551 201 1405 [email protected] Dept. of Cellular Biochemistry DE-37070 Göttingen fax +49 551 201 1197

➔ GREECE Prof. Theodore Fotsis Director, Laboratory of GR-45110 Ioannina tel +30 265 10 97560 [email protected] Biological Chemistry fax +30 265 10 97868 Faculty of Medicine University of Ioannina Prof. Charalambos Savakis Faculty of Medicine Vassilika Vouton tel +30 2810 391114/391088 [email protected] University of Crete and P.O. Box 1385 fax +30 2810 391950 Institute of Molecular GR-71110 Heraklion Biology & Biotechnology Crete (IMBB-FORTH)

➔ HUNGARY Ms Klara Papp Hungarian Academy of Nádor u. 7 tel +36 1 327 3000/2538 kpapp@offi ce.mta.hu Sciences (MTA) HU-1051 Budapest fax +36 1 327 3000/2539 Offi ce for International Cooperation Prof. László Patthy Institute of Enzymology Karolina út 29 tel +36 1 209 3537 [email protected] Biological Research Centre HU-1113 Budapest fax +36 1 466 5465 Dr János Pusztai Hungarian Academy of Nádor u. 7 tel +36 1 327 3000/2536 jpusztai@offi ce.mta.hu Sciences (MTA) HU-1051 Budapest fax +36 1 411 6370 Offi ce for International Cooperation

➔ 48 EMBC delegates and advisers (as of January 2006)

➔ ICELAND Dr Eiríkur Steingrímsson Biochemistry and Vatnsmýrarvegur 16 tel +354 525 4270 [email protected] Molecular Biology IS-101 Reykjavík fax +354 525 4886 Faculty of Medicine University of Iceland

➔ IRELAND Dr Lucy Cusack Science & Technology Division Wilton Park House tel +353 1 607 30 80 [email protected] Forfás Wilton Place fax + 353 1 607 32 60 IE-Dublin 2 Ms Helen Dixon Offi ce of Science and Technology Kildare Street tel +353 1 631 22 36 [email protected] Department of Enterprise, IE-Dublin 2 fax +353 1 631 28 12 Trade and Employment Dr Mary Kelly Biotechnology Directorate Wilton Park House tel +353 1 607 30 00 mary.kelly@sfi .ie Science Foundation Ireland (SFI) Wilton Place fax +353 1 607 32 60 IE-Dublin 2

➔ ISRAEL Prof. Marvin Edelman Dept. of Plant Sciences IL-76100 Rehovot tel +972 8 934 3301/39 [email protected] Weizmann Institute of Science fax +972 8 946 9124 Dr Mahmoud Taya Ministry of Science and Haqirya Hamizrahit tel +972 2 541 1126 [email protected] Technology Bldg 3 fax +972 2 532 2124 Life Science Division P.O. Box 49100 IL-91490 Jerusalem

➔ ITALY Dr Antonino Cianca Ministry of Treasury Via XX Settembre no 97 tel +39 06 476 13512 [email protected] The State General IT-00187 Roma fax +39 06 481 4724 Accounting Department I.G.A.E. Offi ce X Prof. Glauco Tocchini-Valentini Institute of Cell Biology (CNR-IBC) Via E. Ramarini 32 tel +39 06 906 0317 [email protected] Campus A. Buzzati-Traverso IT-00016 fax +39 06 900 91261 Monterotondo Scalo (RM)

www.embo.org/embc | [email protected] ➔ 49 EMBC delegates and advisers (as of January 2006)

➔ NETHERLANDS Dr Jaap Kuiper Royal Netherlands Academy of Kloveniersburgwal 29 tel +31 20 551 0730/728 [email protected] Arts and Sciences (KNAW) Postbus 19121 fax +31 20 620 4941 NL-1000 GC Amsterdam Prof. Peter J. Weisbeek University of Utrecht Padualaan 8 tel +31 30 253 3580 [email protected] Dept. of Molecular Genetics NL-3584 CH Utrecht fax +31 30 251 3655

➔ NORWAY Dr Berit Johne Research Council of Norway Stensberggata 26 tel +47 22 03 7422 [email protected] NO-0131 Oslo fax +47 22 03 7362 Prof. Aurora Martinez Dept. of Biomedicine Jonas Lies vei 91 tel +47 55 58 6427 [email protected] University of Bergen NO-5009 Bergen fax +47 55 58 6300

➔ POLAND Prof. Andrzej Jerzmanowski Laboratory of Pawinskiego 5a tel +48 22 659 6072 [email protected] Plant Molecular Biology PL-02-106 Warsaw (ext. 5704) Warsaw University fax +48 22 658 4636 Institute of Biochemistry and Biophysics, Polish Academy of Sciences (IBB-PAS) Ms Maria Klimkiewicz Ministry for Wspólna 1/3 tel +48 22 628 32 89 [email protected] Scientifi c Research and PL-00-529 Warsaw fax +48 22 628 35 34 Information Technology Dept. of International Cooperation

➔ PORTUGAL Ms Maria José Almeida Offi ce for International v. 5 de Outubro, 85-5° tel +351 21 782 83 44 [email protected] Relations in Science and PT-1050-050 Lisbon fax +351 21 797 16 87 Higher Education (GRICES) Prof. Carmo Fonseca Faculty of Medicine Av. Professor Egas Moniz tel +351 21 794 01 57 [email protected] University of Lisbon PT-1649-028 Lisbon fax +351 21 795 17 80 Institute of Molecular Medicine Dr Claudio Sunkel Institute for Rua do Campo Alegre 823 tel +351 22 607 49 00 [email protected] Molecular and Cell Biology PT-4150-180 Porto fax +351 22 609 91 57 University of Porto

➔ 50 EMBC delegates and advisers (as of January 2006)

➔ SLOVENIA Prof. Franc Gubensek Dept. of Biochemistry Jamova 39 tel +386 1 477 32 50 [email protected] J. Stefan Institute SI-1000 Ljubljana fax +386 1 257 35 94 Ms Radojka Verckoˇ Ministry of Higher Education, Trg OF 13 tel +386 1 478 46 83 [email protected] Science and Technology SI-1000 Ljubljana fax +386 1 478 4719 Dept. of International Cooperation and European Affairs

➔ SPAIN Mr Luis. M. Delgado Deputy Director General José Abascal 4.2 tel +34 91 594 86 20 [email protected] International Programmes & ES-28003 Madrid fax +34 91 594 86 43 Organisms Ministry of Education and Science Ms Cristina Espa Felip Technical Adviser José Abascal 4.2 tel +34 91 594 86 18 [email protected] International Programmes & ES-28003 Madrid fax +34 91 594 86 43 Organisms Ministry of Education and Science) Prof. Juan Modolell Centre of Molecular Biology Cantoblanco tel +34 91 497 50 73 [email protected] CSIC-UAM ES-28049 Madrid fax +34 91 497 47 99

➔ SWEDEN Dr Brita Beije The Swedish Research Council Regeringsgatan 56 tel +46 8 546 44 249 [email protected] Natural and Engineering Sciences SE-103 78 Stockholm fax +46 8 546 44 144 Prof. Marianne Sommarin Dept. of Plant Biochemistry Getingevägen 60 tel +46 46 222 77 92 [email protected] Lund University SE-222 41 Lund fax +46 46 222 41 16 Chemical Center

➔ SWITZERLAND Dr Isabella Beretta State Secretariat for Hallwylstrasse 4 tel +41 31 322 84 17 [email protected] Education and Research CH-3003 Bern fax +41 31 322 78 54 Multilateral Research Cooperation Prof. Rolf Zeller Developmental Genetics Mattenstrasse 28 tel +41 61 267 27 25 [email protected] DKBW Centre for Biomedicine CH-4058 Basel fax +41 61 267 39 59 University of Basel Medical School

www.embo.org/embc | [email protected] ➔ 51 EMBC delegates and advisers (as of January 2006)

➔ TURKEY Prof. Ahmet Ademoglu Biomedical Engineering Institute Bebek tel +90 212 259 64 18 [email protected] Bogazici University TR-34342 Istanbul fax +90 212 257 50 30

➔ UNITED KINGDOM Dr Mike Davies Medical Research Council (MRC) 20 Park Crescent tel +44 20 7637 6021 mike.davies@headoffi ce.mrc.ac.uk UK-London W1B 1AL fax +44 20 7636 6289 Dr Kevin Moreton Medical Research Council (MRC) 20 Park Crescent tel +44 20 7670 5239 kevin.moreton@headoffi ce.mrc.ac.uk UK-London W1B 1AL fax +44 20 7637 6003 Mr Gary Walker Medical Research Council (MRC) 20 Park Crescent tel +44 20 7670 5121 gary.walker@headoffi ce.mrc.ac.uk UK-London W1B 1AL fax +44 20 7580 6198 Mr Nigel Watts Medical Research Council (MRC) 20 Park Crescent tel +44 20 7670 6292 nigel.watts@headoffi ce.mrc.ac.uk UK-London W1B 1AL fax +44 20 7580 6198

➔ 52 scale of contributions

contributions from EMBC member states

Scale of contributions 2004–2006 Budget for 2005 % EURO

Austria 2.0900 261,212 Belgium 2.5944 324,253 Croatia 0.2032 25,396 Czech Republic 0.6139 76,726 Denmark 1.5800 197,471 Finland 1.2362 154,502 France 14.8830 1,860,103 Germany 20.7922 2,598,645 Greece 1.3928 174,075 Hungary 0.5573 69,652 Iceland 0.0903 11,286 Ireland 0.9230 115,358 Israel 1.0958 136,955 Italy 12.1778 1,522,002 Netherlands 4.0805 509,988 Norway 1.6929 211,569 Poland 2.1200 264,961 Portugal 1.1368 142,079 Slovenia 0.2332 29,146 Spain 6.4358 804,357 Sweden 2.4625 307,767 Switzerland 3.1173 389,605 Turkey 2.3194 289,883 United Kingdom 16.1718 2,021,179 total 100 12,498,170

(based on net national income at factor cost)

www.embo.org/embc | [email protected] ➔ 53 EMBO council members 2005

council members 2005

year(s) elected name country 2005 Anton Berns NL – Amsterdam 2001, 2004 Erik Boye (Vice-Chair) NO – Oslo 2003 Margaret Buckingham FR – Paris 2005 Roberto di Lauro IT – Naples 2000, 2003 Susan Gasser (Chair) CH – Basel 2002, 2005 Ingrid Grummt DE – Heidelberg 2004 Tim Hunt UK – London 2005 Daniel Louvard FR – Paris 2002, 2005 Carlos Martínez-A. ES – Madrid 2001, 2004 Sean Munro UK – Cambridge 2000, 2003 Paul Nurse US – New York 2000, 2003 Giora Simchen IL – Jerusalem 2004 Kai Simons DE – Dresden 2004 Gunnar von Heijne SE – Stockholm 2003 Maciej Zylicz˙ PL – Warsaw

ex offi cio Christiane Nüsslein-Volhard EMBO Secretary General Marja Makarow EMBC President Frank Gannon EMBC Secretary General Fotis Kafatos/Iain Mattaj EMBL Director General Ronald Plasterk Chair, EMBL SAC Daniela Rhodes Chair, EMBO Fellowship Committee Pico Caroni Chair, EMBO Course Committee Maria Leptin Chair, EMBO Membership Committee Roberto Sitia Chair, EMBO Science & Society Committee Regine Kahmann Chair, EMBO Young Investigator Committee Eric Westhof Chair, EMBO Publications & Electronic Information Committee

➔ 54 committee members & auditors 2005

EMBO committee members & auditors 2005

course committee membership committee science & society committee auditors (EMBO members) 2003 Pico Caroni (Chair) 2005 Ueli Aebi 2003 Lauri Aaltonen Diter von Wettstein 2004 Miquel Coll 2003 Andrés Aguilera 2005 Andrea Barta David J. McConnell 2002 Jonathan Howard 2002 Ruth Arnon 2005 Wendy Bickmore 2002 Philip Ingham 2005 Carl-Henrik Heldin 2004 Dénes Dudits internal auditor (EMBL) 2005 Dirk Inzé 2004 Andrzej Legocki 2004 Benjamin Geiger Stefan Bäckman 2004 Howard Jacobs 2002 Maria Leptin (Chair) 2005 Ernst Hafen 2003 Batsheva Kerem 2005 Antonio Malgaroli 2003 Matthias Hentze external auditors 2005 Maria Persico 2005 Paolo Sassone-Corsi 2001 Mary Osborn (Tribunal de Contas, Lisbon, Portugal) 2005 Anne Ridley 2005 Veronica van Heyningen 2002 Roberto Sitia (Chair) Maria Isabel Cabaço Antunes 2005 Philippe Sansonetti 2002 Hans Wolf-Watz 2005 Claudio Sunkel Maria da Luz Pedroso de Faria 2005 Detlef Weigel publications & electronic fellowship committee information committee young investigator committee 2005 Robin Allshire 2004 Thierry Boon 2005 Michael Bevan 2004 Peter Becker 2001 Graham Cameron 2005 Thomas Boehm 2002 John Diffl ey 2005 Gianni Cesareni 2004 Martino Bolognesi 2004 Bauke Dijkstra 2003 Ari Helenius 2003 S. Dusko Ehrlich 2005 Peter Ekblom 2003 Dino Moras 2003 Jiríˇ Forejt 2004 Nicolas Glaichenhaus 2005 Angela Nieto 2005 Elisa Izaurralde 2004 Leszek Kaczmarek 2005 Erich Nigg 2002 Regine Kahmann (Chair) 2005 Jürgen Knoblich 2005 Václav Pacesˇ 2004 Hans Krokan 2003 Angela Krämer 2005 Leena Peltonen 2004 Doron Lancet 2004 Wilhelm Krek 2003 Eric Westhof (Chair) 2003 Gines Morata 2004 Montserrat Pages 2004 Anthony Pugsley 2000 Daniela Rhodes (Chair) 2001 Varda Rotter 2004 Angela Santoni

www.embo.org/about_embo/council_committees.html | [email protected] ➔ 55 EMBO council members 2006

council members 2006

year(s) elected name country 2005 Anton Berns NL – Amsterdam 2001, 2004 Erik Boye (Vice-Chair) NO – Oslo 2003, 2006 Margaret Buckingham FR – Paris 2005 Roberto di Lauro IT – Naples 2002, 2005 Ingrid Grummt DE – Heidelberg 2004 Tim Hunt (Chair) UK – London 2005 Daniel Louvard FR – Paris 2002, 2005 Carlos Martínez-A. ES – Madrid 2006 Marjori Matzke AT – Vienna 2001, 2004 Sean Munro UK – Cambridge 2006 Benny Shilo IL – Rehovot 2006 David Shore CH – Geneva 2004 Kai Simons DE – Dresden 2004 Gunnar von Heijne SE – Stockholm 2003, 2006 Maciej Zylicz˙ PL – Warsaw

ex offi cio Christiane Nüsslein-Volhard EMBO Secretary General Marja Makarow EMBC President Frank Gannon EMBC Secretary General Iain Mattaj EMBL Director General Paul Nurse Chair, EMBL SAC Daniela Rhodes Chair, EMBO Fellowship Committee Pico Caroni Chair, EMBO Course Committee Maria Leptin Chair, EMBO Membership Committee Roberto Sitia Chair, EMBO Science & Society Committee Regine Kahmann Chair, EMBO Young Investigator Committee Eric Westhof Chair, EMBO Publications & Electronic Information Committee

➔ 56 committee members & auditors 2006

EMBO committee members & auditors 2006 (year elected)

course committee membership committee science & society committee auditors (EMBO members) 2006 Yehudit Bergman 2005 Ueli Aebi 2003 Lauri Aaltonen Diter von Wettstein 2003 Pico Caroni (Chair) 2003 Andrés Aguilera 2006 Adriano Aguzzi David J. McConnell 2004 Miquel Coll 2006 Rob Benne 2005 Andrea Barta 2005 Dirk Inzé 2006 Brigitte Gicquel 2005 Wendy Bickmore internal auditor (EMBL) 2004 Howy Jacobs 2005 Carl-Henrik Heldin 2004 Dénes Dudits Stefan Bäckman 2003 Batsheva Kerem 2006 George Kollias 2004 Benjamin Geiger 2005 Maria Persico 2004 Andrzej Legocki 2003 Matthias Hentze external auditors 2005 Anne Ridley 2002 Maria Leptin (Chair) 2002 Roberto Sitia (Chair) (Tribunal de Contas, Lisbon, Portugal) 2005 Philippe Sansonetti 2005 Antonio Malgaroli 2005 Claudio Sunkel Maria Isabel Cabaço Antunes 2005 Detlef Weigel 2005 Veronica van Heyningen 2006 Durdica Ugarkovic´ Maria da Luz Pedroso de Faria

publications & electronic fellowship committee information committee young investigator committee 2005 Robin Allshire 2004 Thierry Boon 2005 Michael Bevan 2006 Bernd Bukau 2005 Gianni Cesareni 2005 Thomas Boehm 2004 Bauke Dijkstra 2003 Ari Helenius 2004 Martino Bolognesi 2004 Nicolas Glaichenhaus 2003 Dino Moras 2003 S. Dusko Ehrlich 2004 Leszek Kaczmarek 2005 Angela Nieto 2003 Jiríˇ Forejt 2005 Jürgen Knoblich 2005 Erich Nigg 2005 Elisa Izaurralde 2003 Angela Krämer 2006 Steve Oliver 2002 Regine Kahmann (Chair) 2004 Wilhelm Krek 2005 Václav Pacesˇ 2004 Hans Krokan 2004 Montserrat Pages 2005 Leena Peltonen 2004 Doron Lancet 2004 Anthony Pugsley 2003 Eric Westhof (Chair) 2003 Gines Morata 2000 Daniela Rhodes (Chair) 2001 Varda Rotter 2004 Angela Santoni

www.embo.org/about_embo/council_committees.html | [email protected] ➔ 57 EMBO members elected in 2005

Dario Alessi School of Life Sciences ➞ signal transduction ➞ protein kinases University of Dundee ➞ PDK1 ➞ LKB1 ➞ WNK1 ➞ WNK4 Dundee, United Kingdom

Silvia Arber Biocenter ➞ neuronal circuit assembly ➞ development University of Basel ➞ transcription factors Basel, Switzerland

Philip Avner Mouse Molecular Genetics Unit ➞ epigenetics ➞ X inactivation Pasteur Institute ➞ multifactorial/polygenic inheritance Paris, France

Stephen D. Bell MRC Cancer Cell Unit ➞ DNA replication ➞ Archaea ➞ evolution ➞ MCM Hutchison MRC Research Centre Cambridge, United Kingdom

Walter Birchmeier Max Delbrück Centre for ➞ Wnt/β-catenin ➞ HGF/Met in development Molecular Medicine (MDC) ➞ tumour progression Berlin, Germany

➔ 58 members elected in 2005

Stephen D.M. Brown Medical Research Council (MRC) ➞ mouse genetics ➞ mouse models of human disease Mammalian Genetics Unit ➞ genetics of deafness Harwell, United Kingdom

József Burgyán Agricultural Biotechnology Center (MBK) ➞ plant-virus interaction ➞ RNA silencing Institute of Plant Biology ➞ silencing suppressor proteins Gödöllö, Hungary

Jean-Laurent Casanova Laboratory of Human Genetics of ➞ human genetics of infectious diseases Infectious Diseases ➞ primary immunodefi ciencies French National Institute for Health and Medical Research (INSERM) Paris, France

Maria Antonietta De Matteis Department of Cell Biology and Oncology ➞ membrane traffi cking ➞ Golgi Consorzio Mario Negri Sud (CMNS) ➞ signalling ➞ phosphoinositides Santa Maria Imbaro (Chieti), Italy

Riccardo Fodde Josephine Nefkens Institute ➞ colorectal cancer ➞ Wnt/β-catenin signalling Erasmus Medical Centre (EMC) ➞ cancer stem cells Rotterdam, Netherlands

www.embo.org/communities/members.html | [email protected] ➔ 59 EMBO members elected in 2005

Robert P. Fuchs Genome Instability and Carcinogenesis ➞ damaged DNA replication ➞ genome instability French National Center for ➞ DNA repair ➞ mutagenesis Scientifi c Research (CNRS) Marseille, France

Kenn Gerdes Department of Biochemistry & ➞ bacterial cell cycle ➞ DNA segregation Molecular Biology ➞ bacterial auto-toxins University of Southern Denmark Odense, Denmark

Pierre Gönczy Swiss Institute for ➞ cell division ➞ C. elegans ➞ polarity Experimental Cancer Research (ISREC) ➞ centrosome ➞ genetics ➞ genomics Epalinges s/Lausanne, Switzerland

Edith Heard Mammalian Developmental Epigenetics Group ➞ epigenetics ➞ X inactivation ➞ genomic imprinting French National Center for ➞ mouse development Scientifi c Research (CNRS) Paris, France

Christine Holt Department of Anatomy ➞ axon ➞ navigation ➞ growth cone ➞ retina University of Cambridge ➞ translation ➞ guidance molecules Cambridge, United Kingdom

➔ 60 members elected in 2005

Andreas E. Kulozik Department of Paediatrics ➞ NMD ➞ 3’ end RNA processing University of Heidelberg ➞ paediatric haematology/oncology Heidelberg, Germany

Achim Leutz Max Delbrück Centre for ➞ gene regulation ➞ haematopoiesis Molecular Medicine (MDC) ➞ leukaemogenesis Berlin, Germany

Julian Lewis Cancer Research UK ➞ notch signalling ➞ ear ➞ gut ➞ segmentation clock London Research Institute ➞ mathematical modelling London, United Kingdom

Joachim Lingner Swiss Institute for ➞ telomeres ➞ telomerase ➞ genome stability Experimental Cancer Research (ISREC) ➞ DNA damage response Epalinges s/Lausanne, Switzerland

Michael H. Malim Department of Infectious Diseases ➞ HIV ➞ pathogenesis ➞ innate viral resistance King’s College London, School of Medicine ➞ accessory genes ➞ assembly London, United Kingdom

www.embo.org/communities/members.html | [email protected] ➔ 61 EMBO members elected in 2005

Maria G. Masucci Microbiology and Tumor Biology Center ➞ tumour virus ➞ EBV ➞ immunology, Karolinska Institute ➞ antigen processing ➞ ubiquitin Stockholm, Sweden

Harvey T. McMahon Neurobiology Division ➞ exocytosis ➞ endocytosis ➞ neurotransmission MRC Laboratory of Molecular Biology ➞ membrane ➞ curvature ➞ dynamin Cambridge, United Kingdom

Christoph W. Müller European Molecular Biology Laboratory (EMBL) ➞ transcriptional regulation ➞ chromatin organisation Grenoble Outstation ➞ nuclear transport Grenoble, France

Ulf Nehrbass Pasteur Institute Korea ➞ cell biology ➞ nucleus ➞ gene regulation Seoul, Korea

Luke O’Neill Department of Biochemistry ➞ cytokines ➞ IL-1 receptor/Toll-like receptor Trinity College Dublin superfamily ➞ NF-κB Dublin, Ireland

➔ 62 members elected in 2005

Linda Partridge Centre for Ageing Research ➞ ageing ➞ lifespan ➞ fecundity ➞ evolution University College London ➞ genetics ➞ Drosophila London, United Kingdom

Jerzy Paszkowski Laboratory of Plant Genetics ➞ epigenetics ➞ chromatin ➞ plants University of Geneva Geneva, Switzerland

Laurence H. Pearl Section of Structural Biology ➞ structural biology ➞ DNA repair Institute of Cancer Research ➞ molecular chaperones ➞ signal transduction London, United Kingdom

Félix Rey Pasteur Institute ➞ mechanistic biology ➞ structural virology Paris, France ➞ membrane fusion

Mart Saarma Institute of Biotechnology ➞ neurotrophic factors ➞ signal transduction University of Helsinki ➞ neural development Helsinki, Finland

www.embo.org/communities/members.html | [email protected] ➔ 63 EMBO members elected in 2005

Kári Stefánsson deCODE genetics ➞ population genetics ➞ complex traits Reykjavik, Iceland ➞ population history ➞ selection

Jens Stougaard Department of Molecular Biology ➞ plant molecular genetics ➞ symbiosis receptors University of Aarhus ➞ signal transduction ➞ development Aarhus, Denmark

Giulio Superti-Furga Research Center for Molecular Medicine of ➞ molecular medicine ➞ systems biology the Austrian Academy of Sciences (CeMM) ➞ signal transduction, kinases Vienna, Austria

Alfonso Valencia Protein Design Group ➞ bioinformatics ➞ protein structure and function Spanish National Biotechnology Centre (CNB) ➞ text mining Madrid, Spain

Hervé Vaucheret Cellular Biology Laboratory ➞ plant biology ➞ genetics ➞ epigenetics ➞ siRNA Jean-Pierre Bourgin Institute ➞ miRNA ➞ development Versailles, France

➔ 64 members elected in 2005

Isabelle Vernos Center for Genomic Regulation (CRG) ➞ morphogenesis ➞ microtubule ➞ spindle Barcelona, Spain ➞ chromosome ➞ kinase ➞ cell cycle

Stephen W. Wilson Department of Anatomy & ➞ forebrain development Developmental Biology ➞ CNS laterality & asymmetry ➞ eye development University College London London, United Kingdom

Ira Mellman Department of Cell Biology ➞ antigen presentation ➞ epithelial polarity associate member Ludwig Institute for Cancer Research ➞ dendritic cells ➞ endosome New Haven, USA

Roger Y. Tsien Department of Pharmacology ➞ molecular engineering ➞ neuronal plasticity associate member Howard Hughes Medical Institute (HHMI) ➞ cancer imaging and therapy La Jolla, USA

Bert Vogelstein Johns Hopkins Oncology Center ➞ cancer ➞ genetics associate member Baltimore, USA

www.embo.org/communities/members.html | [email protected] ➔ 65 EMBO advisory editorial boards & senior editors 2005

The EMBO Journal and EMBO reports

A Adriano Aguzzi F Alain Fischer Rolf Kemler Julie Ahringer Richard A. Flavell Wilhelm Krek Kari Alitalo G Henrik Garoff Robb Krumlauf Geneviève Almouzni Susan M. Gasser Werner Kühlbrandt Frances M. Ashcroft Benjamin Geiger L Michel Lazdunski B Andrea Ballabio Ingrid Grummt Tomas Lindahl Mariano Barbacid H Christian Haass M Bernard Malissen Yves-Alain Barde Ernst Hafen Christopher J. Marshall Jiríˇ Bártek Alan Hall Carlos Martínez-A. David C. Baulcombe Stephen C. Harrison Joan Massagué Jean D. Beggs F. Ulrich Hartl Iain W. Mattaj Anton J. Berns Ari Helenius Marjori A. Matzke Michael J. Berridge Kristian Helin Jacopo Meldolesi Heinrich Betz Michael O. Hengartner Edwin Milgrom Wendy A. Bickmore Regine Hengge Dino Moras August Böck Matthias W. Hentze Jorge Moscat Johannes L. Bos Christopher F. Higgins Sean Munro Chris Bowler Nobutaka Hirokawa N Michael S. Neuberger Erik Boye Tim Hunt Walter Neupert Bernd Bukau Tony Hunter Paul Nurse Meinrad Busslinger Nancy E. Hynes O Moshe Oren C Iain D. Campbell I Philip W. Ingham P Peter J. Parker Gennaro Ciliberto Dirk Inzé Tony Pawson Christine E. Clayton J Richard J. Jackson Hugh R.B. Pelham Hans Clevers Stephen P. Jackson Nikolaus Pfanner Pascale Cossart Reinhard Jahn Jonathon Pines D Pietro V. De Camilli Thomas J. Jentsch Hidde L. Ploegh Elisabetta Dejana Josef Jiricny Olaf Pongs Bauke W. Dijkstra K Regine Kahmann R Daniela Rhodes Giulio F. Draetta Roland Kanaar Jean-David Rochaix E Anne Ephrussi Eric Karsenti S Helen R. Saibil

➔ 66 www.embojournal.org | www.emboreports.org advisory editorial boards & senior editors 2005

The EMBO Journal and EMBO reports (cont.) Molecular Systems Biology

Philippe J. Sansonetti senior editors A Julie Ahringer senior editors Bertrand Séraphin The EMBO Journal Charles Auffray Molecular Systems Biology David J. Sherratt David C. Baulcombe B Ewan Birney Ruedi Aebersold Ben-Zion Shilo Ari Helenius Thomas L. Blundell Peer Bork Roberto Sitia Tim Hunt D Thomas Deisboeck George Church James C. Smith Tony Hunter E Jan Ellenberg Leroy Hood Daniel St. Johnston Michael Elowitz Edison Liu T David Tollervey senior editor F Alan R. Fersht Anna Tramontano EMBO reports Stan Fields Richard Treisman Frank Gannon G Mark Gerstein Bryan M. Turner H Reinhart Heinrich V Gerrit van Meer Frank Holstege Joël Vandekerckhove Sung Hou Kim W Detlef Weigel K Hiroaki Kitano Stephen C. West L Doron Lancet Eric Westhof Andrew J. Link Dale B. Wigley N Jeremy Nicholson Alfred Wittinghofer O Stephen G. Oliver Dieter H. Wolf P Bernhard Palsson Hans Wolf-Watz R Rama Ranganathan Richard D. Wood S Luis Serrano Y Ada E. Yonath Lucy Shapiro Z Marino Zerial Pamela Silver Maciej Zylicz˙ Michael Snyder T Janet Thornton Masaru Tomita V Marc Vidal W Lothar Willmitzer Y John Yates

www.embojournal.org | www.emboreports.org www.molecularsystemsbiology.com ➔ 67 EMBO selected papers from EMBO’s journals 2005

The EMBO Journal EMBO reports articles science & society Rusanescu G, Yang W, Bai A, Neel BG, Feig LA Savignac M, Pintado B, Gutierrez-Adan A, Oehmke JF (2005) Commerce and freedom (2005) Tyrosine phosphatase SHP-2 is a Palczewska M, Mellstrom B, Naranjo JR (2005) of inquiry. While threats against research mediator of activity-dependent neuronal Transcriptional repressor DREAM regulates laboratories make the headlines, freedom of research is under more serious attack from excitotoxicity. EMBO J 24: 305 – 314 T-lymphocyte proliferation and cytokine gene expression. EMBO J 24: 3555 – 3564 commercial pressures. EMBO Rep 6: 3 – 7 Kouskouti A, Talianidis I (2005) Histone modifi - Tanaka M, Kamata R, Sakai R (2005) Phospho- Hanski I (2005) Landscape fragmentation, cations defi ning active genes persist after biodiversity loss and the societal response. rylation of ephrin-B1 via the interaction with transcriptional and mitotic inactivation. The longterm consequences of our use of claudin following cell-cell contact formation. EMBO J 24: 347 – 357 natural resources may be surprising and EMBO J 24: 3700 – 3711 unpleasant. EMBO Rep 6: 388 – 392 Roux A, Cuvelier D, Nassoy P, Prost J, Bassereau Ivaska J, Vuoriluoto K, Huovinen T, Izawa I, P, Goud B (2005) Role of curvature and Tata JR (2005) One hundred years of hormones. Inagaki M, Parker PJ (2005) PKCepsilon- phase transition in lipid sorting and fi ssion of A new name sparked multidisciplinary research mediated phosphorylation of vimentin membrane tubules. EMBO J 24: 1537 – 1545 in endocrinology, which shed light on chemical controls integrin recycling and motility. communication in multicellular organisms. Wang Q, Suzuki A, Mariconda S, Porwollik S, EMBO J 24: 3834 – 3845 EMBO Rep 6: 490 – 496 Harshey RM (2005) Sensing wetness: Krummenacher C, Supekar VM, Whitbeck JC, Rose SPR (2005) Human agency in the neuro- a new role for the bacterial fl agellum. Lazear E, Connolly SA, Eisenberg RJ, Cohen GH, centric age. Philosophers and scientists resort EMBO J 24: 2034 – 2042 Wiley DC, Carfí A (2005) Structure of unliganded to dualistic explanations to reconcile the age- HSV gD reveals a mechanism for receptor- old dichotomy between determinism and ‘free Bigay J, Casella J-F, Drin G, Mesmin B, Antonny mediated activation of virus entry. will’, but agency is an integral part of human B (2005) ArfGAP1 responds to membrane EMBO J 24: 4144 – 4153 biology. EMBO Rep 6: 1001 – 1005 curvature through the folding of a lipid packing sensor motif. EMBO J 24: 2244 – 2253 Brenner D, Golks A, Kiefer F, Krammer PH, Arnold R Pigliucci M (2005) Science and fundamentalism. (2005) Activation or suppression of NFkappaB A strategy on how to deal with anti-science Kalies KU, Allan S, Sergeyenko T, Kroger H, by HPK1 determines sensitivity to activation- fundamentalism. EMBO Rep 6: 1106 – 1109 Romisch K (2005) The protein translocation induced cell death. EMBO J 24: 4279 – 4290 channel binds proteasomes to the endoplasmic reviews Trewick SC, McLaughlin PJ, Allshire RC (2005) reticulum membrane. mini-reviews Methylation: lost in hydroxylation? EMBO J 24: 2284 – 2293 Mikkers H, Frisén J (2005) Deconstructing stemness. EMBO J 24: 2715 – 2719 EMBO Rep 6: 315 – 320 Col E, Caron C, Chable-Bessia C, Legube G, van Meer G (2005) Cellular lipidomics. Michelsen K, Yuan H, Schwappach B (2005) Gazzeri S, Komatsu Y, Yoshida M, Benkirane M, Hide and run. Arginine-based endoplasmic- EMBO J 24: 3159 – 3165 Trouche D, Khochbin S (2005) HIV-1 Tat targets reticulum-sorting motifs in the assembly of Tip60 to impair the apoptotic cell response to Haglund K, Dikic I (2005) Ubiquitylation and heteromultimeric membrane proteins. genotoxic stresses. EMBO J 24: 2634 – 2645 cell signaling. EMBO J 24: 3353 – 3359 EMBO Rep 6: 717 – 722

➔ 68 www.embojournal.org www.emboreports.org selected papers from EMBO’s journals 2005

Molecular Systems Biology reviews (cont.) news & views Andrews NW (2005) Membrane repair and Knight TF (2005) Engineering novel life. Locke JCW, Southern MM, Kozma-Bognár L, immunological danger. EMBO Rep 6: 826 – 830 Mol Syst Biol doi:10.1038/msb4100028 Hibberd V, Brown PE, Turner MS, Millar AJ (2005) Extension of a genetic network model Blow JJ, Tanaka TU (2005) The chromosome cycle: Bussemaker HJ (2006) Modeling gene expression by iterative experimentation and mathematical coordinating replication and segregation. control using Omes Law. Mol. Syst. Biol. analysis. Mol Syst Biol Second in the Cycles Review Series. doi:10.1038/msb4100055 doi:10.1038/msb4100018 EMBO Rep 6: 1028 – 1034 Styczynski MP, Fischer CR, Stephanopoulos GN Melen GJ, Levy S, Barkai N, Shilo BZ (2005) Radtke F, Schweisguth F, Pear W (2005) (2006) The intelligent design of evolution. Threshold responses to morphogen gradients The Notch ‘gospel’. Workshop on Notch Mol Syst Biol doi:10.1038/msb4100065 by zero-order ultrasensitivity. Mol Syst Biol doi:10.1038/msb4100036 Signalling in Development and Cancer. reviews EMBO Rep 6: 1120 – 1125 Maciag K, Altschuler SJ, Slack MD, Krogan NJ, Oda K, Matsuoka Y, Funahashi A, Kitano H (2005) Emili A, Greenblatt JF, Maniatis T, Wu LF (2006) A comprehensive pathway map of epidermal scientifi c reports Systems-level analyses identify extensive growth factor receptor signaling. Denchi EL, Helin K (2005) E2F1 is crucial for coupling among gene expression machines. E2F-dependent apoptosis. Mol Syst Biol doi:10.1038/msb4100014 Mol Syst Biol doi:10.1038/msb4100045 EMBO Rep 6: 661– 668 Saiz L, Vilar JM (2006) Stochastic dynamics of Slonim N, Elemento O, Tavazoie S (2006) Ab initio macromolecular-assembly networks. Tassetto M, Maizel A, Osorio J, Joliot A (2005) genotype-phenotype association reveals Mol Syst Biol doi:10.1038/msb4100061 Plant and animal homeodomains use intrinsic modularity in genetic networks. Mol Syst Biol doi:10.1038/msb4100047 convergent mechanisms for intercellular Andrianantoandro E, Basu S, Karig DK, Weiss R transfer. EMBO Rep 6: 885 – 890 (2006) Synthetic Biology: new engineering Nguyen DH, D'haeseleer P (2006) Deciphering rules for an emerging discipline. Mol Syst Biol principles of transcription regulation in Haase AD, Jaskiewicz L, Zhang H, Lainé S, doi:10.1038/msb4100073 eukaryotic genomes. Mol Syst Biol Sack R, Gatignol A, Filipowicz W (2005) TRBP, doi:10.1038/msb4100054 a regulator of cellular PKR and HIV-1 virus articles expression, interacts with Dicer and functions Dudley AM, Janse DM, Tanay A, Shamir R, Church reports in RNA silencing. EMBO Rep 6: 961– 967 GM (2005) A global view of pleiotropy and Cookson S, Ostroff N, Pang WL, Volfson D, Hasty J phenotypically derived gene function in yeast. (2005) Monitoring dynamics of single-cell gene Lingel A, Simon B, Izaurralde E, Sattler M (2005) expression over multiple cell cycles. Mol. Syst. Biol. doi:10.1038/msb4100004 The structure of the fl ock house virus B2 Mol Syst Biol doi:10.1038/msb4100032 protein, a viral suppressor of RNA interference, Schulze WX, Deng L, Mann M (2005) Phospho- Odom DT, Dowell RD, Jacobsen ES, Nekludova L, shows a novel mode of double-stranded RNA tyrosine interactome of the ErbB-receptor Rolfe PA, Danford TW, Gifford DK, Fraenkel E, recognition. EMBO Rep 6: 1149 –1155 kinase family. Mol. Syst. Biol. Bell GI, Young RA (2006) Core transcriptional doi:10.1038/msb4100012 Foerstner KU, von Mering C, Hooper SD, Bork P regulatory circuitry in human hepatocytes. (2005) Environments shape the nucleotide Chan LY, Kosuri S, Endy D (2005) Refactoring Mol Syst Biol doi:10.1038/msb4100059 composition of genomes. bacteriophage T 7. Mol Syst Biol EMBO Rep 6: 1208 –1213 doi:10.1038/msb4100025

www.molecularsystemsbiology.com ➔ 69 EMBO long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Austria Reim, Austrian University of Zurich, MPI-CBG, Dresden, A genetic screen for regulators of organ Gerlinde Switzerland Germany growth in Drosophila melanogaster Sieberer, Austrian University of York, BOKU, Vienna, Towards the identifi cation of a novel branch Tobias UK Austria regulatory hormone by molecular analysis of MAX1 in Arabidopsis thaliana Teis, Austrian University of California, Innsbruck Medical Cellular mechanisms of quality control for David San Diego, USA University, Austria cell surface trans-membrane proteins

Belgium Dobbelaere, Belgian Gurdon Institute, Institute of Biochemistry, Characterising the maturation of mitotic Jeroen Cambridge, UK Zurich, Switzerland centrosomes in Drosophila Lemey, Belgian University of Oxford, Rega Institute, Population genetic modelling and analysis of Philippe UK Leuven, Belgium HIV transmission histories Migeotte, Belgian MSKCC, New York, IRIBHM, Brussels, Genetic regulation of cell migration events Isabelle USA Belgium occurring during early mouse development: Role of Rac1 and search for new genes Pearcy, Belgian University of Lausanne, ULB, Brussels, Queen number regulation in Solenopsis Morgan Switzerland Belgium invicta – a functional genomic approach Viatour, Belgian Stanford University, University of Liege, Mechanisms of tumour suppression upon Patrick USA Belgium re-introduction of the retinoblastoma (Rb) gene in Rb-mutant tumour cells

Croatia Bjedov, Croatian University College London, Necker Institute, Paris, The role of functional domains of Chico in Ivana UK France regulation of lifespan in Drosophila Hasan, Croatian Pasteur Institute, Paris, University of Rijeka, Transcription factors in NK cell development Milena France Croatia Stojic, Croatian Dulbecco Telethon IMCR, Zurich, Identifi cation of novel signalling and Lovorka Institute, Naples, Italy Switzerland transcription regulators involved in Polycomb group gene (PcG) expression

Czech Republic Kadlec, Czech University of Oxford, EMBL, Grenoble, Structural studies on hepatitis C virus Jan UK France envelope glycoprotein E2

Denmark Teilum, Danish University of Lund, University of Copenhagen, The aggregation of superoxide dismutase 1 Kaare Sweden Denmark studied by NMR relaxation measurements

Finland Mähönen, Finnish Utrecht University, University of Helsinki, Role of the auxin - PLETHORA regulatory Ari Pekka The Netherlands Finland network in orchestrating root growth and patterning in Arabidopsis ➔ For a list of all organisations and their acronyms see pages 138 –142

➔ 70 long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Finland Stolt, Finnish MPI for Biophysics, HMS, Boston, Structure and function of peptide cont. Peggy Frankfurt, Germany USA transporters

France Achard, French IBMP, Strasbourg, John Innes Centre, How ethylene and abscisic-acid regulate Patrick France Norwich, UK plant growth and development via modulation of the stability of the DELLA proteins Bareyre, French INIM, Munich, Harvard University, Role of immune-derived growth factors for Florence Germany Cambridge, USA axonal remodelling in an animal model of multiple sclerosis Bertrand, French University of California, Pasteur Institute, Paris, Dissecting the genesis of HSCs in the Julien La Jolla, USA France zebrafi sh embryo Blandin, French IBMC, Strasbourg, EMBL, Heidelberg, Chemical mutagenesis in Anopheles Stephanie France Germany gambiae – forward genetic analysis of vector competence to Plasmodium Boucrot, French CBRI, Boston, CIML, Marseille, Assembly of clathrin-coats in endosomes and Emmanuel USA France at the trans-Golgi network Boulin, French ENS, Paris, Columbia University, Molecular and genetic analysis of Thomas France New York, USA Nicotinic Acetylcholine Receptor clustering in C. elegans Boulon, French Wellcome Trust Biocentre, IGMM, Montpelier, Cajal body proteome dynamics: Séverine Dundee, UK France Application of the SILAC heavy isotope and proteomic approach to analyse the fl ux of proteins through Cajal bodies Causeret, French Imperial College London, INSERM, Paris, Regulation of the cytoskeleton during Frederic UK France neuronal development: Characterisation of a new Cdk5 effector Caussinus, French Biocenter, University of EMBL, Heidelberg, Cell rearrangement during branching Emmanuel Basel, Switzerland Germany morphogenesis Chaigneau, French University College London, University Descartes Paris, Investigation of signal processing in Emmanuelle UK France layer 4 of barrel cortex Chaix, French University of Oxford, University of Paris, Genome-wide analyses to identify molecular Raphaelle UK France changes involved in human-specifi c traits Cocquet, French MRC NIMR, London, INSERM, Paris, Determination of Y gene functions in mouse Julie UK France spermiogenesis: Potential involvement of the Sly multi-copy gene family Cordin, French WTCCB, Edinburgh, CMU, Geneva, Revealing the existence of a functional Olivier UK Switzerland network of helicases during splicing

www.embo.org/fellowships | [email protected] ➔ 71 EMBO long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest France De La Barre, French University of Geneva, FRM, Paris, Chromosome 21 transcriptional regulation cont. Anne-Elisabeth Switzerland France study: Mapping global histone modifi cations and DNA methylation Dessaud, French MRC NIMR, London, INSERM, Marseille, Graded Shh signalling and the control of Eric UK France vertebrate neuronal fate Dutertre, French MPI for Brain Research, University of Queensland, The role of the glycine receptor beta subunit Sebastien Frankfurt, Germany Brisbane, Australia in determining both pharmacology and synaptic targetting Falk, French University of Cambridge, CGMC, Lyon, The role of endocytosis in retinal axon Julien UK France guidance Faroudi, French MRC NIMR, London, INSERM, Toulouse, FRET analysis of the spatio-temporal Mustapha UK France activation of Rho-family GTPases in T lymphoyctes Fayard, French FMI, Basel, IGBMC, Illkirch, Understanding a severe thymus phenotype in Elisabeth Switzerland France a PKB mouse model: Molecular mechanism involving specifi c PKB isoforms in thymus and T cell development Ferri, French IBCP, Lyon, Pasteur Institute, Paris, Role(s) of the anti-apoptotic Nrz/Nr-13 Karine France France protein in the zebrafi sh embryo Frelin, French Ontario Cancer Institute, INSERM, Nice, Genetic regulation of self-renewal and Catherine University of Toronto, France differentiation in normal and leukaemic Canada haematopoiesis Fukuhara, French Imperial College, IBS, Grenoble, Structural basis for Slit/Robo signalling Noemi London, UK France Gallois-Montbrun, French King's College, Pasteur Institute, Paris, Regulation of APOBEC3G, Vif and Sarah London, UK France HIV infection Gendrel, French Imperial College, CNRS, Evry, The role of LINE transposable elements in Anne-Valérie London, UK France X-chromosome inactivation Gresh, French IMP, Vienna, Pasteur Institute, Paris, Connecting infl ammation and cancer through Lionel Austria France AP-1 (Activator Protein-1) activity Guillermet-Guibert, French LICR, London, INSERM, Toulouse, The role of the p110beta isoform of Julie UK France PI 3-kinase in endothelial cells and angiogenesis Helfer, French TSRI, La Jolla, Royal Holloway Characterisation of LUX ARRHYTHMO, Anne USA University of London, a newly identifi ed gene essential for Egham, UK circadian rhythms in Arabidopsis thaliana Henry, French University of Stanford, INSERM, Marseille, The role of the infl ammasome during Thomas USA France Francisella tularensis infection Huntzinger, French EMBL Heidelberg, IBMC, Strasbourg, Role of the processing bodies in the Eric Germany France nonsense-mediated mRNA decay in humans

➔ 72 long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest France Jaskolski, French MRC Centre for François Magendie Real time traffi cking of AMPA receptors cont. Frédéric Synaptic Plasticity, Institute, Bordeaux, during synaptic plasticity Bristol, UK France Joly, French Imperial College London, Pasteur Institute, Paris, Functional analysis of HsfA, a novel Nicolas UK France transcriptional activator Jouhet, French University of Cambridge, CEA, Grenoble, Characterisation of proteins involved in Juliette UK France plastid envelope contact sites Lafuste, French VIB, Leuven, INSERM, Creteil, VEGF in neurodegeneration Peggy Belgium France Lariviere, French LMU, Munich, LEBS, Gif-sur Yvette, Structural study of Med8/Med18/Med20, Laurent Germany France a submodule of the Mediator complex Lecaudey, French EMBL Heidelberg, CNRS, Paris, Analysis of the cellular and molecular Virginie Germany France mechanisms underlying the co-ordination of cell movements in a migrating tissue Manel, French University of New York, IGMM, Montpelier, Identifi cation of genes responsible for Nicolas USA France DC-SIGN-mediated enhancement of HIV infection by dendritic cells Meilhac, French Gurdon Institute, Pasteur Institute, Paris, Regionalisation of visceral endodermal cells Sigolène Cambridge, UK France during anterior-posterior patterning of the mouse embryo Mouchel, French University of York, University of Lausanne, Variation in the regulation of the MAX Céline UK Switzerland pathway and correlation with the evolution of plant shoot system architecture Raynaud, French Royal Holloway Institute for Does the E2Fb transcription factor connect Cécile University of London, Plant Biotechnology, auxin to cell division? Egham, UK Orsay, France Rebsam, French University of Columbia, INSERM, Paris, Mechanisms of retinal axon divergence Alexandra New York, USA France at the optic chiasm: The earliest-growing pioneers Salomé, French MPI for Developmental Dartmouth College, Testing the external coincidence model in Patrice Biology, Tübingen, Hanover, USA Arabidopsis accessions Germany Sémon, French Smurfi t Institute, Dublin, Claude Bernard University, Evolutionary genomics and gene loss in Marie Ireland Lyon, France fi sh species Thebault, French NCMLS, Nijmegen, INSERM, Villeneuve D’Ascq, Funtional characterisation and molecular Stéphanie The Netherlands France regulation of the epithelial Mg2+ protein transporter, TRPM6 chanzyme, in the kidney Viatte, French EMBL Heidelberg, Cochin Institute, Paris, Role of Iron Regulatory Protein 1 and 2 and Lydie Germany France cross-talk with the systemic iron-regulator hepcidin: Insights from transgenic mouse models

www.embo.org/fellowships | [email protected] ➔ 73 EMBO long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest France Walburger, French INSERM, Marseille, Biocenter, University of Identifi cation and characterisation of cont. Anne France Basel, Switzerland Brucella molecules involved in its survival in macrophages Zwaenepoel, French University of Geneva, Pasteur Institute, Paris, Beta- and gamma-cytoplasmic actin isoforms Ingrid Switzerland France function: Importance of their amino-terminal sequences

Germany Bartke, German Gurdon Institute, MPI for Biochemistry, Investigating the infl uence of histone Till Cambridge, UK Martinsried, Germany modifi cation patterns on chromatin activity Buschbeck, German CRG, Barcelona, CRG, Barcelona, Oncogene co-operation and loss of Marcus Spain Spain c-Myc regulation in leukaemia Dimmer, German Dulbecco Telethon LMU, Munich, Molecular mechanism of second messengers Kai Stefan Institute, Padova, Italy Germany in mitochondrial shape changes during life and death of the cell Ebert, German IMP, Vienna, University of Halle, Epigenetic control of B cell identity by Anja Austria Germany Pax5 and Polycomb group proteins Fleischer, German University of Salamanca, INSERM, Paris, Structural and functional characterisation of Aarne Spain France a novel membrane protein able to induce an atypical mode of cell death Hack, German Rockefeller University, GSF Institute for The role of TCF3 in stem cell specifi cation in Michael Anton New York, USA Stem Cell Research, the skin Munich, Germany Haupt, German EMBL Grenoble, Technical University of Cristallographic studies on the yeast TFIIIC Melina France Munich, Germany complex Hellmann, German Institute of Biology, MPI for Evolutionary Detecting selection in primate genomes Ines Copenhagen, Denmark Anthropology, Leipzig, Germany Hubner, German CSHL, Cold Spring Harbor, EMBL Heidelberg, Live-cell analysis of Polycomb group (PcG) Michael R USA Germany protein-induced gene silencing Kaja, German University of UMC Leiden, Functional characterisation of low Simon British Columbia, The Netherlands voltage-activated T-type calcium channels in Vancouver, Canada cerebellar slices of wild-type and P/Q-type calcium channel mutant mice Kamena Fongang, German ETH, Zurich, MPI for Developmental Glycosylphosphatidylinositol (GPI) as Jean Faustin Switzerland Biology, Tübingen, anti-toxin malaria vaccine candidate Germany Korbel, German Yale University, EMBL Heidelberg, Exploring the dark matter of the human Jan New Haven, USA Germany genome: Systematic discovery of microRNA genes using high-density oligonucleotide tiling arrays and comparative genome analysis

➔ 74 long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Germany Krueger, German Babraham Institute, University of Erlangen, Higher order chromatin structure in cont. Christel Cambridge, UK Germany imprinting Lachner, German Rockefeller University, IMP, Vienna, Uncovering the function of lysine Monika New York, USA Austria methylation in non-histone proteins Moese, German ETH, Zurich, MPI for Infection Biology, Cell entry of Infl uenza A virus Stefan Switzerland Berlin, Germany Moll, German Karolinska Institute, CSCHAH, Winnipeg, Mechanisms of HIV-1 interference with Markus Stockholm, Sweden Canada CD1-restricted T-cell-mediated immunity Niethammer, German HMS, Boston, EMBL Heidelberg, Regulation of growth rate by nuclear and Philipp USA Germany cytoplasmic parameters Probst, German Curie Institute, Paris, University of Geneva, Mouse centromeric and pericentromeric Aline France Switzerland heterochromatin: Functional organisation and memory of identity Prokop, German ETH, Zurich, LMU, Munich, Role of immunological phenomena during Stefan Switzerland Germany central prion pathogenesis Reiling, German Whitehead Institute, University of Zurich, A mammalian reverse genetic screen to Jan Cambridge, USA Switzerland identify and characterise genes that affect the growth of cancer cell lines cultured under conditions that mimic the tumour microenvironment Remus, German Cancer Research UK, University of California, Biochemical analysis of DNA replication Dirk South Mimms, UK Berkeley, USA initiation and development of an in vitro DNA replication system in Saccharomyces cerevisiae Rieping, German University of Cambridge, Pasteur Institute, Paris, Direct structure determination of seven- Wolfgang UK France transmembrane receptors from solution NMR data Sauerwald, German MRC Laboratory of Albert Ludwigs University, Structural and functional analysis of the Anselm Molecular Biology, Freiburg, Germany human telomerase protein/RNA complex Cambridge, UK Schaefer, German University College London, MPI for Medical Research, Cellular basis of odour discrimination in Andreas UK Heidelberg, Germany the mammalian olfactory bulb Schlieker, German HMS, Boston, ZMBH, Heidelberg, Dissecting the function of a viral Christian USA Germany isopeptidase Schulz, German King's College London, University of Maryland, Analysis of microarray-based imprinted Reiner UK USA gene identifi cation Schumacher, German EMC, Rotterdam, MPI for Biochemistry, Cancer and ageing Björn The Netherlands Martinsried, Germany

www.embo.org/fellowships | [email protected] ➔ 75 EMBO long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Germany Schwab, German CSHL, Cold Spring Harbor, MPI for Developmental Chromatin regulation in plant stem cells cont. Rebecca USA Biology, Tübingen, Germany Simons, German MSSM, New York, Freiburg University Planar polarity in renal development and Matias USA Hospital, Germany disease Sprick, German AMC, Amsterdam, DKFZ, Heidelberg, Apoptosis sensitivity of tumour stem cells Martin The Netherlands Germany Stark, German MIT, Cambridge, EMBL Heidelberg, Regulatory networks of tissue-specifi c gene Alexander USA Germany expression in Drosophila Vodermaier, German IFOM, Milan, IMP, Vienna, Understanding the assembly pathway Hartmut Italy Austria of kinetochores through biochemical reconstitution and structural analysis Weber, German MRC Laboratory of University of Halle, Role of yeast Bsd2 and its human Ernst Molecular Biology, Germany homologues N4WBP5 and N4WBP5A in Cambridge, UK recognition and sorting of membrane proteins

Greece Briasouli, Greek University of California, Institute of Creation of a knock-in mouse that Paraskevi San Francisco, USA Cancer Research, conditionally expresses p73 using HRT London, UK technology Doitsidou, Greek University of Columbia, MPI for Biophysical Genetic control of left/right asymmetric Maria New York, USA Chemistry, Göttingen, neuronal cell fate specifi cation in C. elegans Germany Giagtzoglou, Greek BCM, Houston, IMBB-FORTH, Elucidating the function of Importin 13 (love) Nikolaos USA Heraklion, Greece in axon guidance and synaptogenesis Harkiolaki, Greek University of Oxford, Weatherall Institute of The structural basis of T cell receptor Maria UK Molecular Medicine, cross-reactivity Oxford, UK Pavlopoulos, Greek University of Cambridge, IMBB-FORTH, Heraklion, Identifi cation of Ubx-regulated targets Anastasios UK Greece at different time points during Drosophila haltere development Pitsouli, Greek HMS, Boston, IMBB-FORTH, Heraklion, Use of Zinc Finger Nucleases for the Chrysoula USA Greece generation of knockouts in Drosophila

Hungary Katona, Hungarian IBS, Grenoble, University of Leicester, Time-resolved structural studies of the Gergely France UK myosin II motor domain by the combination of X-ray crystallography and crystal fl uorescence microspectrophotometry Kiss, Hungarian MPI-CBG, University of Szeged, Cellular and molecular function of Mihaly Arnold Dresden, Germany Hungary Cajal bodies

➔ 76 long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Hungary Remenyi, Hungarian Eötvös Lóránd University, University of California, Exploring the physiological role of cont. Attila Budapest, Hungary San Francisco, USA a hominid-specifi c trypsin in the brain

Ireland Adrain, Irish MRC Laboratory of Smurfi t Institute, Identifi cation and genetic validation of Colin Molecular Biology, Dublin, Ireland novel substrates of the rhomboid family of Cambridge, UK intramembrane proteases Coghlan, Irish WTSI, Hinxton, University College Dublin, Evolution of the nervous system genome Avril UK Ireland

Israel Berger, Israeli TSRI, La Jolla, Hebrew University of Genetic dissection of innate immunity to Michael USA Jerusalem, Israel infection, using the mouse CytomegaloVirus (MCMV) model Citri, Israeli Stanford University Weizmann Institute of Elucidating the mechanism underlying Ami Medical Center, Science, Rehovot, long-term depression of hippocampal NMDA Palo Alto, USA Israel receptor-mediated synaptic transmission Conacci-Sorrell, Israeli FHCRC, Seattle, Weizmann Institute of A new pathway for Myc function in growth Maralice USA Science, Rehovot, and cancer Israel Frenkiel-Krispin, Israeli MPI for Biochemistry, Weizmann Institute of Three-dimensional organisation of dendritic Daphna Martinsried, Germany Science, Rehovot, spines: Cryo-electron tomography studies Israel Hanz, Israeli HMS, Boston, Weizmann Institute of Cdk5-mediated early changes in synaptic Shlomit USA Science, Rehovot, signalling precede neurodegeneration Israel Kapp-Barnea, Israeli Free University of Berlin, University of Tel Aviv, The role of membrane lipids and adaptor Yaara Germany Israel proteins in signal-mediated sorting of synaptic vesicle proteins Milyavsky, Israeli University of Toronto, Weizmann Institute of A genome scale RNAi screen for genes that Michael Canada Science, Rehovot, Israel control the developmental programme of haematopoietic stem cells Morvinski, Israeli Salk Institute, La Jolla, Weizmann Institute of Silencing of the HER-2 gene in breast cancer Dinorah USA Science, Rehovot, stem cells using RNA interference mediated Israel by lentiviral vectors Mukamel, Israeli University of California, Weizmann Institute of Human mirror neuron system – Roy Los Angeles, USA Science, Rehovot, from single units to system level Israel Shifman, Israeli University of Oxford, Hebrew University of Mapping the genetic basis of neuroticism Sagiv UK Jerusalem, Israel Yeger-Lotem, Israeli MIT, Cambridge, Technion, Haifa, Computational analysis of pathways altered Esti USA Israel in Huntington's and Parkinson's diseases

www.embo.org/fellowships | [email protected] ➔ 77 EMBO long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Italy Buscaino, Italian WTCCB, Edinburgh, EMBL Heidelberg, Identifi cation of new factors involved in Alessia UK Germany RNA Polymerase II coupled gene silencing Calella, Italian University Hospital of EMBL Monterotondo, Analysis of the physiological function of prion Anna Maria Zurich, Switzerland Italy protein and its role in neurodegeneration using a proteomic approach in vivo Cambi, Italian MPI for Biophysical NCMLS, Nijmegen, Dynamics of DC-SIGN microdomains Alessandra Chemistry, Göttingen, The Netherlands mediating recognition and uptake of viruses Germany by dendritic cells Chini, Italian CSIC, Madrid, University of Edinburgh, Dissection of the signalling pathway Andrea Spain UK conveying disease resistance against Pythium infection in Arabidopsis thaliana Cotta-Ramusino, Italian HMS, Boston, IFOM, Milan, Identifi cation of novel proteins interacting Cecilia USA Italy with stalled replication forks Danovi, Italian MRC Laboratory for IFOM, Milan, A screen for oncogenes promoting Davide Molecular Cell Biology, Italy anchorage-independent proliferation London, UK Del Bene, Italian University of California, EMBL Heidelberg, Genetic and laser-surgical delineation of Filippo San Francisco, USA Germany the optomotor pathway Ferrari, Italian University of Zurich, University of Parma, Design and construction of an ankyrin repeat Davide Switzerland Italy library and in vitro selection for high affi nity binders to stabilise and crystallise G-coupled protein receptors membrane proteins Ferrario, Italian University of Nijmegen, PRI, Wageningen, Upstream regulators and downstream targets Silvia The Netherlands The Netherlands of Arabidopsis MADS box transcription factors Lo Celso, Italian Massachusetts General Cancer Research UK, Visualisation and molecular characterisation Cristina Hospital, Boston, USA London, UK of the haematopoietic stem cell niche Parrinello Elliott, Italian University College London, University of California, Schwann cell – fi broblast interactions in Simona UK Berkeley, USA neurofi bromatosis type 1 Romagnani, Italian DRFZ, Berlin, University of Genova, The role of NK cells in auto-immunity Chiara Germany Italy

The Claessen, Dutch University of Oxford, University of Groningen, Molecular basis for chromosome cohesion in Netherlands Dennis UK The Netherlands sporulating cells of Bacillus subtilis Essers, Dutch ISREC, Epalinges, Utrecht University c-Myc and n-Myc function during epidermal Marieke Switzerland Medical Centre, homeostasis and tumourigenesis The Netherlands Koning, Dutch King's College London, CLB, Amsterdam, Mechanism of anti-HIV-1 activity of Fransje A. UK The Netherlands APOBEC3G

➔ 78 long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest The Koster, Dutch Curie Institute, Paris, University of Leiden, Membrane fi ssion by dynamin: A quantitative Netherlands Gerbrand France The Netherlands study of the molecular mechanism and the cont. regulatory role of physical parameters Meulmeester, Dutch Georg August University, Leiden University Regulation of target specifi city for Erik Göttingen, Germany Medical Centre, SUMO isoforms The Netherlands Van de Graaf, Dutch ZMBE, Muenster, Nijmegen University Regulated endo- and exocytosis of Stan Germany Medical Centre, TRPV5 and TRPV6 The Netherlands Van Schaik, Dutch Pasteur Institute, Paris, Wageningen University, Characterisation of regulatory circuits Willem France The Netherlands controlling virulence gene expression in the anthrax bacterium, Bacillus anthracis

Poland Kudla, Polish Harvard University, IIMCB, Warsaw, A library of GFP genes with randomised Grzegorz Cambridge, USA Poland codon usage

Portugal Alves, Portugese UPMC, Paris, University of Arizona, Mass spectrometry analysis of the human Isabel France Tucson, USA neurokinin 1 (NK1) receptor de Paiva Alexandre, Portugese University College ENS, Paris, Control of neurogenesis in vertebrate brain Ana Paula London, UK France Fonseca, Portugese University College MPI for Neurobiology, Determining the functional role of an Rosalina London, UK Munich, Germany olfactory bulb glomerulus in vivo Mota, Portugese Imperial College Biocenter, University of The role of the pH inside the Salmonella Luis Jaime London, UK Basel, Switzerland containing vacuole on type-III secretion triggering and on bacterial intracellular multiplication

Spain Alvarado-Kristensson, Spanish CSIC, Madrid, University of Lund, The role of SAD kinases Maria Teresa Spain Sweden Díaz-Moreno, Spanish MRC NIMR, CSIC, Seville, Interaction of the K-homology splicing Irene London, UK Spain recognition protein with target adenine rich elements Escudero, Spanish MRC Laboratory of MRC Laboratory of Control of proliferation and cell shape in Luis Molecular Biology, Molecular Biology, Drosophila Cambridge, UK Cambridge, UK Farrona, Spanish MPI for Plant Breeding CSIC, Seville, Analysis of TFL2/LHP1 in the regulation Sara Research, Cologne, Spain of fl owering gene expression and molecular Germany characterisation of its interaction with the chromatin

www.embo.org/fellowships | [email protected] ➔ 79 EMBO long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Spain Flames Bonilla, Spanish University of Columbia, INA, Alicante, Dopaminergic cell fate determinants in cont. Nuria New York, USA Spain C. elegans: Characterisation of unc-86 as a general repressor of dopaminergic differentiation Gabaldon, Spanish CSAT, Valencia, CMBI, Nijmegen, Integrative approach for the prediction of Juan Antonio Spain The Netherlands protein function and pathways in the human mitochondrial proteome Gandia-Herrero, Spanish University of York, University of Murcia, Engineering transgenic plants for the Fernando UK Spain phytoremediation of toxic explosives González Huici, Spanish FIRC, Milan, CSIC, Madrid, Mechanisms promoting the formation and Víctor Italy Spain migration of cruciform sister chromatid junctions during chromosome replication Hernanz Falcon, Spanish London Research Institute, CSIC-CNB, Madrid, Characterisation of the early signalling events Patricia UK Spain triggered by the b-glucan receptor Dectin-1 Jimeno, Spanish National University of University of Seville, The role of chromatin in the DNA damage Sonia Ireland, Galway, Ireland Spain response Lluis Viñas, Spanish TIGEM, Naples, CRG, Barcelona, Identifi cation of genes involved in cell Frederuc Italy Spain re-programming using microcell-mediated chromosome transfer Lopez-Rios, Spanish University of Basel, CSIC, Madrid, Setting up a patterning system: Javier Switzerland Spain The regulation and temporal changes in functioning of the transcriptional regulator GLI3 during mouse limb bud development Mingorance Jiménez Spanish University of British University of Barcelona, Mathematical modelling of axonal sprouting de la Espada, Columbia, Vancouver, Spain signalling Ana Canada Oliva-Blanco, Spanish MRC Laboratory of CSIC, Madrid, Structural insight into FtsZ polymer dynamics Maria Angela Molecular Biology, Spain Cambridge, UK Rite, Spanish GSF, Munich, University of Seville, Potential role of astrocytes in neurogenesis Inmaculada Germany Spain after brain injury Urizar, Spanish University of Columbia, IRIBHM, Brussels, GPCR heteroligomerisation: Eneko New York, USA Belgium From the interface to the function Velazquez, Spanish MRC Laboratory of CSIC-CNB, Madrid, Identifi cation of new DIF-1-induced Francisco Molecular Biology, Spain developmental signalling cascade Cambridge, UK components in Dictyostelium discoideum

Sweden Andréasson, Swedish University of Heidelberg, LICR, Stockholm, A role for Hsp110/Stress Seventy E in the Claes Germany Sweden chaperone network – functional factors controlling the chaperone cycle

➔ 80 long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Sweden Aspholm, Swedish IMBV, Oslo, University of Umea, Roles of the PilC and PilV proteins of cont. Marina Norway Sweden Neisseria gonorrhoeae in Type IV pilus-associated functions Helgstrand, Swedish University of Lund, University of Uppsala, Characterisation of two novel superantigen Charlotte Sweden Sweden ligands Karlsson, Swedish University of Dundee, Karolinska Institute, Defi ning role of the PtdIns(3,4)P2-TAPP-PTPL1 Håkan UK Stockholm, Sweden signalling network – implications for insulin resistance and type 2 diabetes Loren, Swedish University of British University of Umea, Genetic and proteomic approaches to Christina Columbia, Vancouver, Sweden characterisation of Caprin-2, a novel regulator Canada of proliferation and differentiation Lundgren, Swedish CRG, Barcelona, University of Stockholm, Studies of alternative splicing using Josefi n Spain Sweden microarrays Nelander, Swedish MSKCC, New York, University of Gothenburg, Epistasis networks in human cancer : Sven USA Sweden Pathway modelling and prediction of targets for multiplex cancer therapy Rytkonen, Swedish Imperial College London, Karolinska Institute, Identifi cation of novel Salmonella effectors Anne UK Stockholm, Sweden Sandin, Swedish MRC Laboratory of Karolinska Institute, Structural analysis of the telomerase enzyme Sara Molecular Biology, Stockholm, Sweden by single particle cryo-electron microscopy Cambridge, UK

Switzerland Busch, Swiss MRC Laboratory of EMBL Heidelberg, The role of neuronal compartmentalisation in Karl Emanuel Molecular Biology, Germany generating specifi c behavioural responses in Cambridge, UK C. elegans Hippenmeyer, Swiss University of Stanford, Biocenter, University of Principles of odourant sensory map Simon USA Basel, Switzerland formation in higher brain centres Kraft, Swiss ETH, Zurich, IMP, Vienna, Characterisation of regulated organelle Claudine Switzerland Austria turnover by autophagy

Turkey Ozbudak, Turkish Cancer Research UK, Cancer Research UK, The somite segmentation clock Ertugrul London, UK London, UK Ozlu, Turkish HMS, Boston, MPI-CBG, Dresden, Biochemical approaches to understand how Nurhan USA Germany the actomyosin cytoskeleton is controlled by microtubules during cytokinesis

United Campbell, British WEHI, Melbourne, University of Dundee, An investigation of the role of Mnt in Kingdom Kirsteen Australia UK Myc-induced haemopoietic malignancies

www.embo.org/fellowships | [email protected] ➔ 81 EMBO long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest United Cockburn, British Pasteur Institute, Paris, University of Oxford, Comparative structure-function analysis Kingdom Joseph France UK of the Dengue virus envelope protein in cont. complex with relevant ligands from the host Gifford, British University of New York, University of Edinburgh, Nitrogen regulatory gene networks: Miriam USA UK Integrating metabolic control of development Leonard, British NIH, Bethesda, MRC Laboratory of Mechanistic studies of protein kinase C Thomas USA Molecular Biology, Cambridge, UK Scaplehorn, British CNRS, Gif-Sur-Yvette, Cancer Research UK, Signalling networks regulating Niki France London, UK cytoskeletal plasticity during long-term memory formation in Drosophila Vickers, British University of Washington, University of Dundee, Novel targets for folate analogues in Timothy St Louis, USA UK Leishmania

other Bubeck, American University of Oxford, HMS, Boston, Structural studies investigating nationalities Doryen UK USA the interaction of TCR with CD3 within the context of a membrane LaCava, American CRG, Barcelona, University of Edinburgh, Molecular analysis of RPL30-regulated John Spain UK spliceosome assembly Lee, American EMC, Rotterdam, MIT, Cambridge, Whole cell recording of hippocampal place Albert The Netherlands USA cell activity in freely behaving rodents Rohde, American MPI-CBG, Dresden, University College Frizzled function and single molecule Laurel Germany London, UK dynamics in cell movement Walter, American Pasteur Institute, Paris, University of Washington, Mechanisms by which antigen transport Lisa France Seattle, USA and peripheral T cell activation confer central nervous system auto-immune disease Alic, Australian University College London, CEA Saclay, Paris, Comprehensive study of the organs and Nazif UK France tissues through which insulin-like signalling affects lifespan in Drosophila Selth, Australian Cancer Research UK, CSIRO, Urrbrae, The cellular role of the elongator complex Luke South Mimms, UK Australia Ivanova, Bulgarian CNRS-IBPC, Paris, University of Uppsala, Study of defective translation termination Natalia France Sweden by the use of modifi ed tmRNA; searching for proteins whose synthesis is affected by lack of release factor methylation under conditions of normal growth or physiological stress Chang, Canadian ISREC, Epalinges, University of Toronto, Identifi cation of factors that regulate Michael Switzerland Canada in vivo the extent of telomere elongation in Saccharomyces cerevisiae

➔ 82 long-term fellowship awards 2005

name nationality host laboratory home laboratory research interest other Chen, Chinese University of Bristol, Goethe University, The SecYEG protein translocation complex: nationalities Min UK Frankfurt, Germany An analysis of the interactions and cont. movements required for channel gating Lou, Chinese Karolinska Institute, USTC, Hefei, Three-dimensional structure of full-length Xiaohua Stockholm, Sweden China nuclear receptor Kirmizis, Cypriot Gurdon Institute, University of Investigating the link between histone Antonis Cambridge, UK Wisconsin-Madison, phosphorylation and 14-3-3 proteins during USA apoptosis Antoun, Egyptian University of Bristol, University of Uppsala, The effects of DBC2 in cancer progression Ayman UK Sweden Prasad, Indian University of Utrecht, IISc, Bangalore, Uncovering a common regulatory Kalika The Netherlands India mechanism for plant organ formation Herman, Indonesian CNRS, Montpelier, Cornell University, Regulation of genomic imprinting Herry France Ithaca, USA Kobayashi, Japanese IBDM, Marseille, Kyoto University, Cross-talk between cell cycle exit and Kenji France Japan transcriptional control of differentiation in chordate embryos Hafalla, Philipinian LSHTM, London, University of New York, Regulation of anti-malaria immune Julius Clemence UK USA responses by transforming growth factor-b and interleukin-10 Elina, Russian Sainsbury Laboratory, University of Moscow, Role of viral RNA silencing suppressor in Nataliya Norwich, UK Russia disease and development Kainov, Russian IGBMC, Illkirch, Institute of Biotechnology, General transcription factor TFIIH at Denis France Helsinki, Finland the crossroad between transcription and DNA repair Moshkin, Russian EMC, Rotterdam, University of Geneva, A role of ubiquitin-specifi c proteases in Yuri The Netherlands Switzerland transcription regulation and gene silencing Zavialov, Russian INSERM, Valbonne, University of Uppsala, The function of ADA2, a novel Andrey France Sweden adenosine deaminase-related growth factor, in immunity

www.embo.org/fellowships | [email protected] ➔ 83 EMBO long-term fellowships: statistics

applications and awards 2000 – 2005

country from applications % of total awards % of total success rate % Austria 63 1.30 16 1.88 25 Belgium 82 1.69 12 1.41 15 Croatia 23 0.47 6 0.71 26 Czech Republic 48 0.99 6 0.71 13 Denmark 48 0.99 9 1.06 19 Finland 63 1.30 10 1.18 16 France 1034 21.27 187 22.03 18 Germany 540 11.11 118 13.90 22 Greece 98 2.02 25 2.94 26 Hungary 63 1.30 13 1.53 21 Iceland 12 0.25 2 0.24 17 Ireland 47 0.97 6 0.74 13 Israel 252 5.18 42 4.95 17 Italy 321 6.60 43 5.06 13 Netherlands 181 3.72 45 5.30 25 Norway 8 0.16 0 0.00 0 Poland 38 0.78 6 0.71 16 Portugal 74 1.52 22 2.59 30 Slovenia 8 0.16 0 0.00 0 Spain 547 11.25 85 10.01 16 Sweden 231 4.75 30 3.53 13 Switzerland 79 1.63 26 3.06 33 Turkey 31 0.64 3 0.35 10 United Kingdom 262 5.39 34 4.00 13 Eastern Europe 122 2.51 13 1.53 11 USA/Canada 198 4.07 38 4.48 19 Others 388 7.98 52 6.12 13 total 4861 100 849 100 17

➔ 84 long-term fellowships: statistics

applications and awards 1977 – 2005

year applications awards success rate % 2005 1236 198 16 2004 1137 166 15 2003 1080 176 16 2002 789 178 22 2001 645 147 23 2000 707 155 22 1999 830 170 20 1998 790 144 18 1997 831 185 22 1996 898 160 18 1995 877 147 17 1994 806 176 22 1993 739 199 27 1992 626 142 23 1991 571 139 24 1990 526 123 23 1989 460 118 26 1988 455 141 31 1987 383 120 31 1986 333 90 27 1985 340 92 27 1984 305 112 37 1983 294 103 35 1982 276 91 33 1981 274 111 41 1980 242 108 45 1979 254 101 40 1978 235 101 43 1977 236 94 40

www.embo.org/fellowships | [email protected] ➔ 85 EMBO long-term fellowships 2005: geographical distribution

applications

to from Austria Belgium Croatia Czech Rep. Denmark Finland France Germany Greece Hungary Iceland Ireland Israel Italy Netherlands Norway Poland Portugal Slovenia Spain Sweden Switzerland Turkey UK Eastern Europe USA/Canada Others total

Austria 1232 111 11 Belgium 2221221221 17 Croatia 0 Czech Rep. 2114 Denmark 1141 81218 Finland 22 1 16 France 1 5 2 2 2 17 10 3 31 14 4 2 1 1 12 1 1 9 11 10 20 132 Germany 1 1 1 5 17 4 1 4 3 4 4 1 15 3 1 1 3 2 6 12 89 Greece 41 16 Hungary 22 Iceland 0 Ireland 2111117 Israel 22 Italy 14431531628 Netherlands 41221141122 32132344 Norway 11114 Poland 1113 Portugal 15118 Slovenia 11 Spain 1 13 5 11 3 7 4 1 1 7 3 6 1 2 13 69 Sweden 2 3 1 1 3 6 16 1 5 1 1 5 3 1 4 5 5 63 Switzerland 111151 34 341 633125889 Turkey 0 UK 1 2 1 5 1 1 61 31 5 2 3 5 15 10 3 7 1 39 12 3 2 8 11 11 39 279 EMBL 1112 5 52 1 2 1 21 3 27 Eastern Europe 1 1 USA/Canada 3 7 5 1 4 71 43 6312 37 19 6 3 5 1 26 23 111 20 1 1 300 Others 210411 1 133 26

total 10 27 6 18 8 21 260 149 26 18 210 49 72 42 1 16 23 4 124 68 20 7 58 39 42 116 1236

➔ 86 long-term fellowships 2005: geographical distribution

awards

to from Austria Belgium Croatia Czech Rep. Denmark Finland France Germany Greece Hungary Iceland Ireland Israel Italy Netherlands Norway Poland Portugal Slovenia Spain Sweden Switzerland Turkey UK Eastern Europe USA/Canada Others total

Austria 11 2 Belgium 1 1 Croatia 0 Czech Rep. 0 Denmark 1 1 Finland 0 France 111212312195 Germany 14 1 222 21 1 16 Greece 0 Hungary 11 Iceland 0 Ireland 112 Israel 0 Italy 12 2 5 Netherlands 112 1 111 8 Norway 11 Poland 0 Portugal 0 Slovenia 0 Spain 212117 Sweden 11 1 14 Switzerland 11 4 3 21 1 1 1 15 Turkey 0 UK 1 2 1 1 19 8 2 2 1 3 2 3 6 3 1 1 1 1 6 64 EMBL 31 4 Eastern Europe 0 USA/Canada 12 7114 83 1 3 21147 3 Others 11

total 3 5 3 1 1 2 46 33 6 3 02 11 12 7 0 1 4 0 17 9 3 2 6 5 6 10 198

www.embo.org/fellowships | [email protected] ➔ 87 EMBO short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Belgium Capoen, Belgian John Innes Centre, University of Zwijnaarde, Investigation of calcium spiking events in Ward Norwich, UK Belgium Sasbania rostrata during nodulation Delputte, Belgian University of Dundee, University of Gent, Identifi cation of the porcine arterivirus Peter UK Belgium protein-mediating virus attachment to the sialoadhesin receptor using a soluble, Fc-tagged sialoadhesin Hallez, Belgian Yale University, University of Namur, Phenotypical characterisation of Caulobacter Régis New Haven, USA Belgium crescentus mutant strains complemented with Brucella abortus orthologus genes Leyman, Belgian EPFL-LCB, Lausanne, Faculty of Medicine and Role of phosphatidylinositol-4, 5- Shirley Switzerland Health Sciences, bisphosphate-regulation of cofi lin in cell Gent, Belgium adhesion and spreading Vlieghe, Belgian GSF, Neuherberg, University of Gent, Investigating the role of endoreduplication in Kobe Germany Belgium Arabidopsis thaliana

Croatia Kovacic, Croatian University of Düsseldorf, Rudjer Boskovic Institute, Molecular biology of GDSL hydrolases Filip Germany Zagreb, Croatia Staresincic, Croatian EMC, Rotterdam, IMCR, Zurich, Co-ordination of dual incision and repair Lidija The Netherlands Switzerland synthesis in mammalian nucleotide excision repair

Czech Abrhamova, Czech Göteborg University, Charles University, Microarray analyses to study the role in RNA Republic Katerina Sweden Prague, Czech Republic metabolism of S. cerevisiae Prp45p – the essential pre-mRNA processing protein Hynek, Czech Technical University of ICT, Prague, Proteome analysis of the membrane of barley Radovan Denmark, Czech Republic aleurone layer for identifi cation of proteins Lyngby, Denmark involved in germination signalling Matalová, Czech King’s College, Academy of Sciences, Apoptosis in the primary enamel knot Eva London, UK Brno, Czech Republic - modulations of caspase machinery using tooth slice cultures Skopek, Czech IPB, Halle, Institute of Plant Analysis of enzymatic properties of CHS-like Josef Germany Molecular Biology, homologues from hop Ceské Budejovice, Czech Republic

Denmark Hoffmann, Danish HHMI, New Haven, University of Leicester, Global down regulation of double-strand Eva USA UK breaks and meiotic regression of sgs1 mutant cells Jakobsen, Danish DFKZ, Heidelberg, University of Dissipative particle dynamics study of the Ask Frode Germany Southern Denmark, COPI/COPII vesicle machinery Odense, Denmark

➔ For a list of all organisations and their acronyms see pages 138 –142

➔ 88 short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Finland Ihalainen, Finnish University of Linz, University of Jyväskyllä, Characterisation of biotin-avidin interactions Teemu Austria Finland Johansson, Finnish NKI, Amsterdam, The NPHI, Helsinki, Finland The functional relationship of ORP1L and RILP Marie Netherlands Metsä-Ketelä, Finnish HKI, Jena, University of Turku, Engineering diversity to aromatic polyketides Mikko Germany Finland

France Allegra, French IMP, Vienna, University of Crete, Implication of ERF in epithelial-mesenchymal Maryline Austria Heraklion, Greece transition Bajenoff, French NIAID, Bethesda, IPMC, Valbonnes – Elucidation of the mechanisms by which Marc USA Sophia Antipolis, NK cells infl uence CD4 T cell differentiation in France mice infected with the intracellular parasite Leishmania major Beckoüet, French Cardiff University DBJC, Gif-sur-Yvette, Effect of yeast RNA polymerase II mutants on Frédéric School of Medicine, UK France transcription coupled repair Dalous, French MPI for Biochemistry, CEA Grenoble, Actin cytoskeleton dynamics and protein Jérémie Martinsried, Germany France relocalization in live cells under shear forces Dumollard, French University College London, CNRS/UPMC, Regulation of mitochondrial respiration at the Rémi UK Villefranche-sur-Mer, onset of development France Girard, French University of Cologne, University of Oxford, Generation of mice-carrying mutations Christophe Germany UK causing human neonatal diabetes Jaubert, French Imperial College London, INRA Rennes, Le Rheu, Development of RNAi on the pea aphid Stéphanie UK France (Acyrthosiphon pisum) La Carbona, French PICR, Manchester, University of Rennes, Dynamic organisation of spindle and F-actin Stéphanie UK France ring in mitotic S. pombe kin1D cells Leclerc, French TSRI, La Jolla, Children’s Hospital, Selection of ligand-specifi c antibodies against Estelle USA Zurich, Switzerland RAGE from antibody phage display library Lesterlin, French University of Uppsala, Laboratory of Microbiology Study of a new cell cycle phenotype due to Christian Sweden and Molecular Genetics, chromosome disruption in Escherichia coli Toulouse, France Lobréaux, French University of Geneva, INRA, Montpelier, Investigation of Suf protein function in Stéphane Switzerland France chloroplast iron-sulfur cluster biogenesis Martineau, French MPI for Biophysical CNRS, Gif-sur-Yvette, Immunoisolation of D-serine-containing Magalie Chemistry, Göttingen, France vesicles from glial cells and characterisation Germany of the vesicular D-serine transport Pinaud, French CBS, Montpelier, University of California, Quantum dots tracking of GPI-anchored Fabien France Los Angeles, USA proteins in lipid bilayer models Robert, French Free University of Brussels, University of Utrecht, Reconstitution of Omp85 protein and its Viviane Belgium The Netherlands interaction with substrate proteins

www.embo.org/fellowships | [email protected] ➔ 89 EMBO short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest France Ruel, French HMS, Boston, University of Nice, Genome-wide screen for genes involved cont. Laurent USA France in the secretion and release of cholesterol- modifi ed hedgehog Seibt, French Free University of Brussels, University Claude Bernard, Study of the regulation and function of genes Julie Belgium Bron, France potentially controlled by neurogenin-2 by in utero electroporation of the developing mouse brain Veiga, French University of Groningen, INRA, Jouy-en-Josas, Identifi cation of the genes induced by Patrick The Netherlands France introduction of PG breaks in Lactococcus lactis

Germany Dinkelaker, German University of Rome, J.W. Goethe University, Role of archaeal RLI in translation initiation of Stéphanie Italy Frankfurt, Germany S. solfataricus Elsner, German Cornell University, Göteborg University, Multiphoton fl uorescence correlation and Markus Ithaca, USA Sweden fl uorescence cross-correlation spectroscopy of Golgi enzymes Grütz, German MRC Laboratory of Institute of Medical Generation of mice defi cient for Gerald Molecular Biology, Immunology, Charité, ZFP36L2/Tis11D Cambridge, UK Berlin, Germany Koch, German Leiden University Medical J.W. Goethe University, Viral inhibitors of the transporter associated Joachim Center, The Netherlands Frankfurt, Germany with antigen processing Leptin, German WTSI, Cambridge, University of Cologne, Innate immune genes and genetic Maria UK Gemany polymorphism in the zebrafi sh (Dario rerio) Martic, German NIMR, London, University of Ioannina, Chromatin remodelling proteins containing Goran UK Greece polyglutamic stretches: Involvement in thymocyte development Michel, German OCEAC-IRD, Yaounde, EMBL Heidelberg, Infl uence of three SRPN immunity proteins on Kristin Cameroon Germany transmission of the human malaria parasite, Plasmodium falciparum, by Anopheles gambiae mosquitoes Pischon, German University of Oulu, Charité International The skeletal phenotype of lysyl oxidase Nicole Finland University Clinic, Berlin, knock-out mice Germany Schmidt, German COSI, Torino, Free University of Berlin, Role of g-BAR in neuronal membrane traffi c Michael Italy Germany and polarisation Szilagyi, German HMS, Boston, University of Cologne, IgG1+ cells in AID defi cient mice. Does the Balint USA Germany responsible mechanism utilise common CSR between S regions and is it also able to mediate SHM? Temme, German IGH, Montpelier, France University of Halle, Composition and function of the CCR4/NOT Claudia Germany complex in Drosophila melanogaster

➔ 90 short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Greece Kosmopoulov, Greek University of The National Hellenic The effect of 3 new classes of glycogen Magda Newcastle-upon-Tyne, Research Foundation, phosphorylase inhibitors on glycogenolysis UK Athens, Greece and glycogen synthesis in intact rat hepatocytes Papavasileiou, Greek MRC Laboratory of Mycology Reference Cell signalling in Dictyostelium development Dimitris Molecular Biology, Laboratory, and differentiation Cambridge, UK Athens, Greece Petrakis, Greek NKI, Amsterdam, The IMBB-FORTH, Heraklion, Crystallisation of the mitochondrial TIM0 Nicolaos Netherlands Greece chaperone/translocase complex Roukos, Greek EMBL Heidelberg, University of Patras, Studies of DNA damage-mediated proteolysis Vassilis Germany Greece of the licensing factor Cdt1 using advanced microscopy techniques Tsellou, Greek HMS, Charlestown, University of Athens, Identifi cation of novel tumour-specifi c genes Erasmia USA Greece associated with Notch overexpression in mouse mammary cancer progression Typas, Greek LBPA, Cachan, Free University of Berlin, Differences in promoter binding by Athanasios France Germany the vegetative RNA polymerase Es70 and the “stress” RNA polymerase Ess Tzimourakas, Greek INSERM U536, Paris, IMBB-FORTH, Heraklion, Functional characterisation of neural and Alexandros France Greece glial TAG-1 in myelinated fi bers

Hungary Horváth, Hungarian University of Heidelberg, Semmelweis University, Regulation of the blood pressure by Béla Germany Budapest, Hungary nitric oxide-mediated modulation of smooth muscle contractility Mádi, Hungarian University of Rostock, University of Debrecen, Investigation on the post-translational András Germany Hungary modifi cation of the cell death substrate lamin protein characteristic for the ced-1 cell death mutant of the nematode Caenorhabditis elegans Mártonfalvi, Hungarian University of Florence, University of Pécs, Mechanics of actin-tintin interaction explored Zsolt Italy Hungary at the sarcomeric level Novák, Hungarian Cancer Research UK, Budapest University Computational modelling of DNA replication Béla London, UK of Technology, Hungary control in the fi ssion yeast cell cycle

Ireland Faller, Irish CNIO, Madrid, The Conway Institute, Methylation profi ling of markers for William Spain Dublin, Ireland melanoma progression Furney, Irish IMIM, Barcelona, University College Dublin, Molecular evolution of genes involved in Simon John Spain Ireland human cancer Ryan, Irish St. George’s Hospital University College Cork, Identifi cation of unknown fl agellar genes in Kieran Medical School, Ireland H. pylori London, UK

www.embo.org/fellowships | [email protected] ➔ 91 EMBO short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Ireland Tosh, Irish EMBL Monterotondo, University of Bath, Molecular basis of hepatocyte differentiation cont. David Italy Claverton Down, UK

Israel Avni, Israeli University of Wageningen, Tel Aviv University, A functional genomics approach to identify Adi The Netherlands Israel signalling components involved in defence responses induced by the ethylene-inducing xyalanase elicitor Citri, Israeli University of Texas, MD The Weizmann Institute of Analysis and modelling of novel feedback- Ami Anderson Cancer Center, Science, Rehovot, loop negative regulators of EGFR signalling Houston, USA Israel Fridkin, Israeli Cornell University, The Hebrew University of The role of Matefi n in C. elegans ageing Alexandra Ithaca, USA Jerusalem, Israel Friedman, Israeli Utah State University, Tel Aviv University, Calculation of kinetic isotope effects for Ran Logan, USA Israel proton transfer reactions on the molecular surface Goldstein Magal, Israeli University of Madrid, Tel Aviv University, Live cell analysis of the intracellular Lee Spain Israel localization and mechanisms of MAL function Kerem, Israeli Pasteur Institute, The Hebrew University of Replication dynamics and chromosomal Batsheva Paris, France Jerusalem, Israel instability in the human genome Machluf, Israeli CNRS, Gif-sur-Yvette, The Weizmann Institute of The involvement of the Drosophila langouste Vered France Science, Rehovot, Israel dystrophin-like proteins in learning and memory Maizels, Israeli/ The Rockefeller University, Hebrew University, The search for mRNA targets of the VICKZ Yael American New York, USA Hadassah Medical School, family in the developing mouse brain Jerusalem, Israel Milstein, Israeli NYU School of Medicine, The Weizmann Institute of Visualisation of the veto cell immune synapse Oren New York, USA Science, Rehovot, Israel Nabel-Rosen, Israeli King’s College London, The Weizmann Institute of Real-time analysis of hypothalamic Helit UK Science, Rehovot, Israel dopaminergic neural progenitors Padan, Israeli MPI of Biophysics, Hebrew University of Crystal structure of the active open Etana Frankfurt, Germany Jerusalem, Israel conformation of NhaA-Na+/H+ antiporters, structure/function of membrane proteins Poraty, Israeli ETH, Zurich, Tel Aviv University, Genome-wide expression in an Arabidopsis Limor Switzerland Israel RACs mutant Ring, Israeli University of Rome, Ben Gurion University of Development of an in vitro translation system Gabriela Italy the Negev, Beer-Sheva, for halophilic Archaea Israel Trachtenberg, Israeli EMBL Heidelberg, Hebrew University, Swimming biophysics and mechanics of the Shlomo Germany Hadassah Medical School, helical mollicute Spiroplasma melliferum – Jerusalem, Israel a minimal form of life

➔ 92 short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Israel Yaakov, Israeli University Pompeu Fabra, Hebrew University of Hyperactive Hog1 molecules: A unique tool cont. Gilad Barcelona, Spain Jerusalem, Israel for revealing the biology and biochemistry of MAPKs Zeidner, Israeli Texas A&M University, Technion, Haifa, Marine cyanobacterial photosynthesis Gil Tamu, USA Israel regulation by cyanophages

Italy Avitabile, Italian MBC, Dresden, Cardiological Centre, Application of biopolymers for in vitro Daniele Germany Monzino Foundation, reconstituted heart tissue using stem cells Milan, Italy Biroccio, Italian University Claude Bernard, Regina Elena Cancer Interplay between hTERT and TRF2 for Annamaria CNRS, Lyon, France Institute, Rome, Italy telomere capping Brunetta, Italian University of Geneva, University of Padova, Italy Isolation of Chlamydomonas reinhardtii Alessia Switzerland mutants affected in photosystem II repair Caruso, Italian University of Buenos Aires, University of Rome, Study of the role of the polyomavirus-α4β1 Maddalena Argentina Italy integrin interaction in virus tissue-tropism and tumorigenicity in vivo Cotta-Ramusino, Italian Pasteur Institute, IFOM, Milan, Analysis of replication intermediates by Cecilia Paris, France Italy molecular combing Cursi, Italian Cancer Research UK, University “Tor Vergata”, Role of caspase-8 tyrosine phosphorylation in Silvia Manchester, UK Rome, Italy human colon cancer cell lines Daviso, Italian MPI for Polymer Research, University of Leiden, NMR above the Boltzmann limit: Eugenio Mainz, Germany The Netherlands A biophysical approach powered by natural photosynthesis Di Donato, Italian Free University of University of Salerno, Femtosecond-visible/mid-infrared Mariangela Amsterdam, Italy pump-probe studies of primary processes The Netherlands of photosynthesis Favaro, Italian University of University of Milan, Conditional ablation of the Sox2 transcription Rebecca Edinburgh, UK Italy factor gene in neural stem cells Fraldi, Italian Women and Children’s TIGEM, Naples, Adeno-associate virus-mediated gene Alessandro Hospital, Adelaide, Italy delivering to CNS of MPS-IIIA mice Australia Grumelli, Italian Duke University University of Milan, Role of pre-synaptic AMPA receptor in Carlotta Medical Centre, Italy modulation of neurotransmitter release Durham, USA Guffanti, Italian CEA Saclay, Gif-sur-Yvette, University of Parma, Effects of chromatin disruption on the Elisa France Italy genomic location of the RNA polymerase III transcription machinery in Saccharomyces cerevisiae Iovino, Italian The Rockefeller University, IRBM, Rome, The role of miRNAs in regulation of human Nicola New York, USA Italy haematopoietic cell lineage decision

www.embo.org/fellowships | [email protected] ➔ 93 EMBO short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Italy La Corte, Italian ETH, Zurich, CNR, Rome, Italy Isolation of naturally occuring VGF peptides cont. Giorgio Switzerland involved in gastrointestinal functions and in the response to injury and infl ammation Laneve, Italian University of Aarhus, University of Rome, Identifi cation of microRNAs expressed in Pietro Denmark Italy neuronal patterning and neuroblastic tumours Lionetti, Italian MPI for Molecular University of Rome, Cell wall characterisation of Arabidopsis Vincenzo Plant Physiology, Italy thaliana plants altered in pectin Golm, Germany methylesterase inhibitors expression Lippi, Italian University of Leicester, University of Modena & Molecular basis of nicotine neuroprotection: Giordano UK Reggio Emilia, Italy The role of calcium transporting proteins Marone, Italian IPK, Gatersleben, ISC, Foggia, Development of three genetic maps for Daniela Germany Italy the dissection of the genetic bases of agronomical key traitsin durum wheat Merone, Italian Louis Pasteur University, CNR, Naples, In vitro evolution of a termostable Luigia Strasbourg, France Italy phosphotriesterase from Sulfolobus solfataricus Nicastro, Italian NIMR, London, University of Parma, Structural characterisation of the complex Giuseppe UK Italy between the Josephin domain of ataxin-3 and the Ubl domain of HHR23B Palma, Italian Karolinska Institute, University of Rome, Molecular mechanisms of primary HIV Paolo Stockholm, Sweden Italy immune response and prime boost strategies to induce long-term memory Pantaleo, Italian Agricultural Biotechnology CNR, Bari, Molecular mechanisms of virus-induced gene Vitantonio Center, Gödöllö, Hungary Italy silencing in Tombusvirus Rigoni, Italian Cancer Research UK, University of Padova, Cellular localization and mode of action of Michela London, UK Italy Taipoxin in primary motor neurons Sisto, Italian Free University of University of Palermo, Analysis of the principal genes involved in Pasqua Sandra Amsterdam, Italy the adenoma-carcinoma progression of The Netherlands colorectal cancer Spadoni, Italian University of Cambridge, University of Rome, Advanced proteomics methods for the Sara UK Italy analysis of the responses induced by oligogalacturonides (OGs) in Arabidopsis thaliana Vernarecci, Italian PICR, Manchester, University of Rome, Functional study of a novel penta-EF protein Stefano UK Italy localized at spindle body in budding yeast Zambelli, Italian EMBL Hamburg, University of Bologna, Structural, molecular and functional Barbara Germany Italy characterisation of proteins involved in cellular metal traffi cking Zanoni, Italian HMS, Boston, University of Milan, Study of the cellular and molecular Ivan USA Italy interactions between dendritic cells and NK cells at the draining lymph nodes using the multiphoton microscopy

➔ 94 short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest The Hemmes, Dutch Agricultural Biology Center, University of Wageningen, Biochemical analysis of tomato-spotted wilt Netherlands Hans Gödöllö, Hungary The Netherlands virus NSs and rice hoja blanca tenuivirus NS3 RNAi suppressor proteins which have a dual role in antiviral RNAi Slofstra, Dutch Oklahoma Medical Academic Medical Center, Activated protein C-induced PAR-1/EPCR- Sjoukje Research Foundation, The Netherlands mediated signalling, sepsis and infl ammation Oklahoma City, USA Tiecke, Dutch Tokyo Insitute of Technology, University of Dundee, UK Lampreys as a model to examine the origin of Eva Yokohama, Japan paired appendages in vertebrates van Duijn, Dutch University of Cambridge, UK University of Utrecht, The Tandem mass spectrometry on high Esther Netherlands molecular weight ions from chaperonin complexes van Manen, Dutch MPI for Biophysical University of Twente, Dynamic fl uorescence microscopy of NADPH Henk-Jan Chemistry, Göttingen, Enschede, The Netherlands oxidase activation in living phagocytes Germany Verweij, Dutch Laboratory of Botany, Free University of Study of the sub-cellular localization Walter Lecce, Italy Amsterdam, of proteins involved in vacuolar lumen The Netherlands acidifi cation and vacuole ontogenesis

Norway Mcleod, Norwegian INRA, Jouy-en-Josas, MATFORSK, Aas, Genome-wide study: Metabolism and gene Anette France Norway regulation in Lactobacillus sakei

Poland Bakowska, Polish IMU, Innsbruck, Polish Academy of Study of ribosomal functions and dynamics Kamilla Austria Sciences, Poznan, Poland Grzela, Polish IBS, Grenoble, Polish Academy of Crystal studies of potato virus Y VPg and its Renata France Sciences, Warsaw, complex with initiation factor eIF4E Poland Juranek, Polish University of Lund, University of Transport and assembly of cytomatrix at Judyta Sweden Warmia and Mazury, presynaptic active zone Olsztyn, Poland Kubica, Polish International University of Jagiellonian University, Staphylococcus aureus survival within Malgorzata Grazyna Bremen, Germany Krakow, Poland human monocyte-derived macrophages Olszewski, Polish Utrecht University IIMCB, Warsaw, The role of TNF-alpha propeptide in storage Maciej Medical Centre, Poland of this cytokine in mast cell granules The Netherlands Rudolf, Polish CNRS, Paris, University of Lodz, Heavy transition organometallic complexes Bogna France Poland for the site-specifi c covalent labelling of proteins

www.embo.org/fellowships | [email protected] ➔ 95 EMBO short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Poland Skowronek, Polish Institute of Biotechnology, IIMCB, Warsaw, Saturation orthogonal mutagenesis to cont. Krzysztof Cuernavaca, Morelos, Poland engineer sequence specifi city of restriction Mexico endonucleases NIaIV and Bsp6I Wieckowski, Polish University of Ferrara, Nencki Institute of The role of mitochondria-associated Mariusz Italy Experimental Biology, membranes in physiological and pathological Warsaw, Poland calcium signals

Portugal Anes Portuguese EMBL Heidelberg, University of Lisbon, High-throughout microarray technology (Ribeiro dos Santos), Germany Portugal and RNAi knockout for a Mycobacterium Elsa phagosome system Barata, Portuguese Utrecht University Institute of Role of Akt/PKB downstream targets Joao Medical Centre, Molecular Medicine, GSK-3 and FoxOs in IL-7-mediated viability The Netherlands Lisbon, Portugal proliferation and growth of leukaemia T-cells Barbosa Morais, Portuguese University of Cambridge, University of Lisbon, Resemblance between teleost gene Nuno Luís UK Portugal duplication and mammalian alternative splicing Douradinha, Portuguese University of Edinburgh, Faculty of Medicine, Immunisation with mutant Plasmodium Bruno UK Lisbon, Portugal parasites Vaz, Portuguese OCMS, Oxford, University of Coimbra, Multidimensional NMR experiments on three Daniela C. UK Portugal human interleukin-4 mutants

Slovenia Frajman, Slovenian University of Uppsala, University of Ljubljana, Molecular phylogenies of Heliosperma, Bozo Sweden Slovenia Sileneae (Caryophyllaceae), based on RNA polymerase genes Zavasnik Bergant, Slovenian EMBL Heidelberg, Josef Stefan Institute, Protease inhibitor cystatin C determination in Tina Germany Ljubljana, Slovenia human dendritic cells by electron microscopy

Spain Alvarez-Garcia, Spanish EMBL Heidelberg, Cancer Research UK, Functional characterisation of Ines Germany Gurdon Institute, the miR-2 family of microRNAs in Cambridge, UK Drosophila melanogaster Bernado Pereto, Spanish EMBL Hamburg, IBS, Grenoble, Structural characterisation of the C-terminal Pau Germany France domain of Sendai virus phosphoprotein. An indispensable protein for viral RNA replication and transcription Blanco-Garcia, Spanish EMBL Heidelberg, University of Barcelona, Genome-wide analysis of the evolutionary Angel Germany Spain history of orphan genes Carazo, Spanish Catholic University of University of Granada, Study of nitrogen fi xation in Halomonas Rafael Fernández Leuven, Heverlee, Belgium Spain maura

➔ 96 short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Spain Cerezo-Guisado, Spanish Imperial College School of Veterinary Transcriptional regulation of neuronal cont. Maria Isabel School of Medicine at Sciences, Cáceres, apoptosis Hammersmith Hospital, Spain London, UK Conde, Spanish University of Cambridge, Cancer Research Institute, Role of histone modifi cations in DNA damage Francisco M. UK Salamanca, Spain and meiotic checkpoints Espada, Spanish MRC Human Genetics Unit, CNIO, Madrid, Role of DNA methyltransferase 1 in the Jesus Edinburgh, UK Spain organisation of chromosome territories Fernandez, Spanish MRC, Cambridge, University of Almeria, Computational techniques in single particle Jose-Jesus UK Spain cryoEM and in cryoET Gil, Spanish CSHL, Cold Spring Harbour, Cancer Research UK, Animal models for studying the role of CBX7 Jesus USA London Research Institute, in cellular homeostasis and cancer UK Grego Bessa, Spanish University of California, National Centre of Role of the s225 gene in zebrafi sh cardiac Joaquim San Francisco, USA Biotechnology, Madrid, development Spain Larrú Meca, Spanish NKI, Amsterdam, The University of Barcelona, Role of p16 in the control of avb3-integrin Laura Netherlands Spain mediated cell migration and invasion Lopez-Aviles, Spanish MHH, Germany University of Barcelona, Role of the MAPKAP K2 in the regulation of Sandra Spain cell cycle progression during stress López-Martín, Spanish MPI of Molecular Plant CICIC, Seville, Spain Metabolomic profi ling of t-DNA tagged Carmen Physiology, Golm, Germany SAT mutants defective in the cytosolic and plastidial SAT and their crossings with respect to abiotic stress Luque Buzo, Spanish NIH, Bethesda, USA UAM, Madrid, Spain Three-dimensional reconstruction methods Daniel of helical assemblies: Tubular structure derived from infectious bursal disease virus Mas Lopez, Spanish Biocenter, University Pompeu Fabra, Analysis of the molecular mechanism Antonio University of Würzburg, Barcelona, Spain underlying the involvement of the decapping Germany complex Lsm1-7 in the replication of positive strand RNA viruses Melchor Fernández, Spanish AFCRI, Philadelphia, CNIO, Madrid, Characterisation of recurrent regions of Lorenzo USA Spain high level amplifi cations in hereditary breast cancer Morcillo, Spanish University College CSIC, Madrid, Sonic hedgehog rescue of Pax2-positive cells Julián London, UK Spain absent in the optic disc of ocular retardation mutant mice Pérez Martínez, Spanish Michigan State University, University of Málaga, Comparative genome analysis of the pPt23A Isabel East Lansing, USA Spain plasmid family of Pseudomonas savastanoi Prado Cabrero, Spanish University of Freiburg, University of Seville, Functional characterisation of carX, a gene Alfonso Germany Spain of the carotenoid oxygenase family in the ascomyvete Fusarium fujikuroi

www.embo.org/fellowships | [email protected] ➔ 97 EMBO short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Spain Reales Rodriguez, Spanish San Raffaele University, University Hospital Manipulating B-cell differentiation and cont. Elena Milan, Italy Puerta Del Mar, function Cadiz, Spain Rodriguez Sanchez, Spanish University of Institute Ramón y Cajal, SFRP1 modifi es growth and directionality of Josana Cambridge, UK Madrid, Spain retinal ganglion cells Roldán Rivero, Spanish CNRS, Lille, France University of Seville, Characterisation of amylopectin structure Isaac Spain and starch composition in soluble starch synthase type IV knock-out mutant of Arabidopsis thaliana Ruiz Lorenzo, Spanish University of CSIC, Madrid, The gene transformer of Anastrepha obliqua Maria Fernanda Napoli Federico II, Spain Naples, Italy Sánchez Durán, Spanish North Carolina University of Málaga, Analysis of the interaction between Miguel State University, Spain TGMV AL1 and plant SCE1/UBC9, the E2 Raleigh, USA sumoylating enzyme Sanjuán Verdeguer, Spanish University of Texas, University of Valencia, Genome complexity, genetic robustness and Rafael Austin, USA Spain the rate of adaptation in bacteriophages Tajadura, Spanish ISREC, Epalinges, University of Salamanca, Is the fi ssion yeast Rho1p activator rgf3 Virginia Switzerland Spain regulated by the septation initiation network? Urbano Fernandez, Spanish Brigham & Women’s University Functional genomic characterisation Jose Maria Hospital, Boston, USA Pablo de Olavide, of migratory processes during midgut Seville, Spain development Valle, Spanish NKI, Amsterdam, UAM, Madrid, Interactions of the Parvovirus NS2 protein Noelia The Netherlands Spain with exportin-1/CRM1 and nuclear pore complex components Veiga, Spanish CBRI, Boston, Pasteur Institute, Paris, Dynamics of endocytic machinery during Esteban USA France bacterial infections

Sweden Stenberg, Swedish ABI, Munich, University of Umea, Characterisation of the POF complex and Per Germany Sweden study of its regulation of chromatin in Drosophila

Switzerland Soldini, Swiss CNIO, Madrid, University of Zurich, Discovery of novel markers and targets for Davide Spain Switzerland detection and/or treatment of early stages of cancer through microarray analysis of cell super-competition.

Turkey Demirel, Turkish HHMI, New Haven, J.W. Goethe University, Peptide transport into lysosomes and Ozlem USA Frankfurt, Germany MHC class II loading by TAPL

➔ 98 short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest Turkey Kutluk Yilmaz, Turkish Rothamsted Research, Ondokuz Mayis University, Identifi cation of soil-borne mosaic virus cont. Nazli Dide Harpenden, UK Samsun, Turkey diseases transmitted by Polymyxa graminis in cereal production areas of Turkey Öztürk, Turkish University of East Anglia, University of Istanbul, Further characterisation of the effects of Mehmet Norwich, UK Turkey replacement of fi ve highly conserved amino acids of subunit I in cbb3-type oxydase of R. capsulatus Topaloglu, Turkish University of Cambridge, Cukurova University, Genetic analysis in a cohort of patients with Ali Kemal UK Adana, Turkey normosmic idiopathic hypogonadotropic hypogonadism

United Edwards, British University of Melbourne, University of Cambridge, Imprinting and expression analysis of Kingdom Carol Ann Australia UK imprinted genes in the Tammar Wallaby Kozlowski, British/ MPI-CBG, Dresden, EMBL Heidelberg, Characterising the forces involved in Cleopatra Polish Germany Germany spindle positioning in the fi rst cell division of C. elegans Le Pichon, British/ Zurich University Hospital, Columbia University, Expression and function of the cellular prion Claire French Switzerland New York, USA protein Prpc in the murine olfactory system Nicol, British University of Bergen, University of Aberdeen, Genomic analysis of soil Archaea in Graeme Norway UK glacier forelands Perrett, British Hutchinson/MRC Research Chinese Academy of Protein misfolding and disease Sarah Centre, Cambridge, UK Sciences, Beijing, China Robson, British HMS, Boston, School of Medical Sciences, Structural analysis of the SecY protein Alice USA Bristol, UK translocation complex and its gating mechanism Stevens, British ETH, Zurich, University of Oxford, UK Cytocrome c maturation in Escherichia coli Julie Maureen Switzerland Wardle, British WIBR, Cambridge, Cancer Research UK, Indentifi cation of T-domain targets in Fiona USA Cambridge, UK zebrafi sh using genome-wide location analysis other Cabeen, American DKFZ, Heidelberg, Yale University, Biochemical characterisation of crescentin, nationalities Matthew T. Germany New Haven, USA a bacterial intermediate fi lament-like protein Dushay, American EMBL Heidelberg, Södertörn University, Analysis of coagulation in Mitchell Germany Huddinge, Sweden Anopheles gambia mosquitoes Carrari, Argentinian MPI for Plant Physiology, INTA, Castelar, Biodiversity exploitation: Identifi cation of Fernando Golm, Germany Argentina metabolic QTLs using wild species tomato Gelman, Argentinian University College Miguel Hernandez Generation of a developmental mice model Diego Matias London, UK University, Alicante, Spain of cortical interneuron defi ciency

www.embo.org/fellowships | [email protected] ➔ 99 EMBO short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest other Laxalt, Argentinian SILS, Amsterdam, University of Mar del Plata, Real time visualisation of NO-induced nationalities Ana Maria The Netherlands Argentina phospholipid signalling in living plant cells cont. Tanos, Argentinian UAM, Madrid, University of Buenos Aires, Role of heme oxygenase-1as a therapeutic Tamara Beatriz Spain Argentina target in the development of tumours induced by the G protein-coupled receptor from the Kaposi’s sarcoma-associated herpes virus Foster, Australian University of Dundee, Centre for Immunology, Nucleolar localization and mobility study Natasha UK Darlinghurst, Australia of two nuclear factors induced during infl ammation in endothelial cells Sutija, Australian University of University of Utrecht, Molecular and cellular mechanisms driving Margareta Edinburgh, UK The Netherlands extension of the embryonic axis in the mouse Cordeiro Júnior, Brazilian King’s College London, University of São Paulo, Genetic mapping of bipolar disorder and Quirino UK Brazil schizophrenia: Genome-wide association by DNA pooling Ganchev, Bulgarian University of University of Utrecht, Biomembrane force probe investigation of Dragomir N. British Columbia, The Netherlands transmembrane peptides incorporated in Vancouver, Canada biomembranes Parvanova, Bulgarian University of Lisbon, University of Cologne, Role of the p47 GTPase IIGP1 in immune Iana Portugal Germany defense against malaria Wang, Chinese MPI for Terrestrial University of Jyväskyllä, Quantitative detection of the community Hong Microbiology, Finland structure and activity of methanotrophs on Marburg, Germany rice roots by molecular techniques Zu, Chinese University of Munich, University of Development of detection of protein Xinlin Germany Western Australia, histidine phosphorylation sites by mass Perth, Australia spectrometry Kurrikoff, Estonian King’s College, Institute of Physiology, Brainstem and midbrain gene expression Kaido London, UK Tartu, Estonia analysis of CCK2 knockout mice using mouse gene expression chip Appunu, Indian INRA, Dijon, Banaras Hindu University, Genetic diversity of native Bradyrhizobium Chinnaswamy France Varanasi, India strain isolates of soybean, cowpea, black gram and green gram from Indian soil Tokuriki, Japanese EMBL Heidelberg, The Weizmann Institute of Analysis of the change of the protein Nobuhiko Germany Science, Rehovot, stability during protein evolution by Israel FOLDF program Haj, Lebanese EMBL Heidelberg, Harvard University, Imaging the regulation of protein tyrosine Fawaz George Germany Boston, USA phosphatase inactivation by reactive oxygen species Loh, Malaysian MDC, Berlin, University of Oxford, Identifi cation of genes causing renal stone Nellie Germany UK disease by cDNA profi ling

➔ 100 short-term fellowship awards 2005

name nationality host laboratory home laboratory research interest other Perez Rueda, Mexican MRC Laboratory of Institute of Biotechnology, Reconstruction of regulatory networks in nationalities Ernesto Molecular Biology, Morelos, Mexico archaeal genomes cont. Cambridge, UK Arif, Pakistani University of Valencia, NIBGE, Faisalabad, Expression analysis of a yeast salt tolerance Anjuman Spain Pakistan gene CtHSR1 in tobacco as plant model system Borisov, Russian University of Rome, Moscow State University, Studies on interaction of the bd-type terminal Vitaliy Italy Russia respiratory oxidase with nitric oxide by time- resolved spectroscopy and amperometry Koryakov, Russian Martin Luther University Novosibirsk State A role of the SuUR protein in processes Dmitry E. Halle-Wittenberg, University, of modifying of histone tails in Drosophila Halle, Germany Russia polytene chromosomes Kraus, Russian SICMMB, Bergen, Moscow State University, Functional analysis of snail, forkhead and Yulia Norway Russia brachyury and their role in regulating morphogenetic events during gastrulation of Nematostella vectensis Laletina, Russian IGBMC, Illkirch, IChBFM, Novosibirsk, Cryo-electron microscopy study of Elena France Russia human ribosome complexes in the termination state of protein synthesis Malygin, Russian University of Leicester, IChBFM, Novosibirsk, CNBP – a novel splicing modulator? Alexey UK Russia Penkov, Russian San Raffaele Hospital, Belozersky Institute, Role of Prep1 homeodomain protein in Dmitry Milan, Italy Moscow, Russia mouse T cell development Petukhov, Russian EMBL Heidelberg, St. Petersburg Global sequence optimisation of protein Michael Germany Nuclear Physics Institute, alpha-helices St. Petersburg, Russia Elliott, South EMBL Heidelberg, University of Natal, Mechanisms for inducing maturation of Edith African Germany South Africa the pathogenic mycobacterial phagosome Chudotvorova, Ukrainian Harvard University, INMED-INSERM, Effect of KCC2-overexpression on presynaptic Ilona Cambridge, USA Marseille, France vesicle cycling Gorbenko, Ukrainian University College Institute of Molecular PTEN-AEBP1 interaction: A possible role in Olena London, UK Biology and Genetics, lipid metabolism and adipocyte differentiation Kyiv, Ukraine Havrylov, Ukrainian Cardiff School of NIEB, Warsaw, Identifi cation of binding partners for Ruk/ Serhiy Biosciences, UK Poland CIN85 adaptor protein by mass spectrometry Ivakhno, Ukrainian Graz University of Institute of Molecular Design and programming of Sergii Technology, Graz, Biology and Genetics, microarray/LS-MS/MS integrative software Austria Kyiv, Ukraine Panasyuk, Ukrainian University College National Academy of Elucidation of the functional importance of Ganna London, UK Sciences of Ukraine, CK2/S6K1 interaction Kyiv, Ukraine

www.embo.org/fellowships | [email protected] ➔ 101 EMBO short-term fellowships: statistics

applications and awards 2000 – 2005

country from applications % of total awards % of total success rate % Austria 10 0.58 7 0.72 70 Belgium 36 2.08 23 2.36 64 Croatia 16 0.92 8 0.82 50 Czech Republic 41 2.37 22 2.25 54 Denmark 18 1.04 9 0.92 50 Finland 16 0.92 12 1.23 75 France 137 7.91 82 8.40 60 Germany 125 7.22 66 6.76 53 Greece 78 4.50 48 4.92 62 Hungary 41 2.37 26 2.66 63 Iceland 8 0.46 3 0.31 38 Ireland 14 0.81 10 1.02 71 Israel 80 4.62 57 5.84 71 Italy 267 15.42 139 14.24 52 Netherlands 45 2.60 29 2.97 64 Norway 8 0.46 5 0.51 63 Poland 70 4.04 31 3.18 44 Portugal 30 1.73 19 1.95 63 Slovenia 20 1.15 11 1.13 55 Spain 266 15.36 152 15.57 57 Sweden 25 1.44 16 1.64 64 Switzerland 23 1.33 10 1.02 43 Turkey 35 2.02 12 1.23 34 United Kingdom 66 3.81 43 4.41 65 Eastern Europe 158 9.12 72 7.38 46 Others 99 5.72 64 6.56 65 total 1732 100 976 100 56

➔ 102 short-term fellowships: statistics

applications and awards 1977 – 2005

year applications awards success rate % 2005 384 201 52 2004 301 167 55 2003 289 138 48 2002 252 170 67 2001 233 124 53 2000 274 176 64 1999 230 138 60 1998 279 143 51 1997 339 188 55 1996 316 180 57 1995 325 187 57 1994 369 203 55 1993 376 209 55 1992 351 213 61 1991 344 194 56 1990 346 211 61 1989 331 199 60 1988 351 211 60 1987 301 212 70 1986 309 215 70 1985 304 221 73 1984 320 226 71 1983 335 223 67 1982 321 213 66 1981 339 235 69 1980 357 242 68 1979 344 243 71 1978 349 244 70 1977 294 213 72

www.embo.org/fellowships | [email protected] ➔ 103 EMBO short-term fellowships 2005: geographical distribution

applications

to from Austria Belgium Croatia Czech Rep. Denmark Finland France Germany Greece Hungary Iceland Ireland Israel Italy Netherlands Norway Poland Portugal Slovenia Spain Sweden Switzerland Turkey UK Eastern Europe Others total

Austria 11 1 11 1 1 7 Belgium 21113 8 Croatia 0 Czech Rep. 1 1 2 Denmark 1 11 3 Finland 1 1 France 115221024111442314 Germany 1211 2 2123 19232 911 6 4 53 Greece 0 Hungary 11 1 3 Iceland 0 Ireland 0 Israel 11 1 3 Italy 21132 1 151 4 21 Netherlands 1112141 111214 51 1 28 Norway 12111 6 Poland 1 1 Portugal 1 1 Slovenia 0 Spain 1 222 1 1211 Sweden 11 11112 3 1 2 12 Switzerland 1113311 12122 19 Turkey 0 UK 2213106 665231 21442 16 85 EMBL 12 2211 11123 17 Eastern Europe 0 Others 2111 551 61041860 1113

total 2738316366 2326 17723 21 59 15 21 5255 46 21 24 383

➔ 104 short-term fellowships 2005: geographical distribution

awards

to from Austria Belgium Croatia Czech Rep. Denmark Finland France Germany Greece Hungary Iceland Ireland Israel Italy Netherlands Norway Poland Portugal Slovenia Spain Sweden Switzerland Turkey UK Eastern Europe Others total

Austria 11 1 1 4 Belgium 1113 Croatia 0 Czech Rep. 0 Denmark 1 1 2 Finland 1 1 France 21 2411162 1 2 Germany 1111 2 212 13212 41 1 3 29 Greece 0 Hungary 11 2 Iceland 0 Ireland 0 Israel 0 Italy 2112121111 Netherlands 1 111 121 1 2 1 1 13 Norway 1 1 2 Poland 0 Portugal 1 1 Slovenia 0 Spain 2 2127 Sweden 11 111 5 Switzerland 11 12111 8 Turkey 0 UK 21 423131 1721 7 344 46 EMBL 11 2111 11112 13 Eastern Europe 0 Others 14316527111638

total 0514113114 1513 817403 27 9 9 5226 33 12 15 201

www.embo.org/fellowships | [email protected] ➔ 105 EMBO young investigators 2005

EMBO Young Investigators selected in 2005

name nationality institute research interest Bellaiche, Yohanns French Curie Institute, Paris, France Cell polarisation in Drosophila Boutros, Michael German DKFZ, Heidelberg, Germany Genetics of signalling pathways Chin, Jason British MRC-LMB, Cambridge, UK Orthogonal translation Chiti, Fabrizio Italian University of Florence, Italy Protein structure in amyloid disease Clausen, Tim German IMP, Vienna, Austria Protein quality control Del Pozo, Miguel A. Spanish CNIC, Madrid, Spain Integrin signalling in cell migration and growth Dutzler, Raimund Austrian University of Zurich, Switzerland Transmembrane ion transport Einsle, Oliver German George August University, Göttingen, Germany Protein systems in nitrogen and iron metabolism Kaessmann, Henrik German/Swedish University of Lausanne, Switzerland Evolution of the human genome Köhler, Claudia German University of Zurich, Switzerland Reproductive development in plants Längst, Gernot German Adolf Butenandt Institute, Munich, Germany Chromatin dynamics Lohmann, Jan German MPI, Tübingen, Germany Stem cell fate in plants Oldroyd, Giles British John Innes Centre, Norwich, United Kingdom Signalling in symbiosis Palmer, Ruth British Umea University, Sweden Receptor Tyrosine Kinase signalling pathways Peeper, Daniel Dutch NKI, Amsterdam, The Netherlands Cellular protection against oncogenic transformation Pilpel, Yitzhak Israeli Weizmann Institute of Science, Rehovot, Israel Gene expression regulation Strick, Terence American Monod Institute, Paris, France Single-molecule analysis of protein/DNA interactions

EMBO/HHMI Startup Grant Recipients 2005

name nationality institute research interest Káldi, Krisztina Hungarian Semmelweis University, Budapest, Hungary Regulation of circadian rhythms Kovacs, Mihaly Hungarian Eötvös Lorand University, Budapest, Hungary Diversity of molecular motor mechanisms Krejci, Lumir Czech Masaryk University, Brno, Czech Republic DNA repair and recombination Loog, Mart Estonian University of Tartu, Estonia Signalling networks in the cell cycle Stefl , Richard Czech Masaryk University, Brno, Czech Republic Protein-RNA complexes Welker, Ervin Hungarian Biological Research Center, Szeged, Hungary Conformational transition of prions

➔ 106 young investigators 2000–2004

EMBO young investigators selected 2000 – 2004

A Adams, Ralf Cramer, Patrick Konieczny, Igor Nichols, Benjamin Spang, Anne Agami, Reuven Currie, Peter Kunji, Edmund Nissen, Poul Stock, Daniela Allain, Frederic D Davis, Daniel L Labib, Karim Noselli, Stephane Sträßer, Katja Alon, Uri de Gier, Jan-Willem Lappalainen, Pekka O Otzen, Daniel Stumpf, Michael Antonny, Bruno Delledonne, Massimo Lecuit, Thomas Owen, David Suomalainen-Wartiovaara, Arber, Silvia Dessen, Andrea Lemaitre, Bruno Owen-Hughes, Tom Anu Arkowitz, Robert Dickson, Barry Levashina, Elena A. Palková, Zdena Szabò, Ildikò Arribas, Joaquin Dominguez, Maria Leys, David P Pellizzoni, Livio T Tamagnone, Luca Ashe, Hilary Donaldson, Anne Logan, Malcolm Peracchi, Alessio Tanaka, Tomoyuki Averof, Michalis E Elena, Santiago Löwe, Jan Perrakis, Anastassis Tavernarakis, Nektarios B Barkai, Naama F Fankhauser, Christian Lygerou, Zoi Peters, Jan-Michael Teichmann, Sarah Barr, Francis Fernandez-Chacon, Rafael M Malnasi Csizmadia, Philpott, Dana Telford, Maximilian Barral, Yves Friml, Jiri Andras Pierre, Philippe Therond, Pascal Batista, Facundo G Glotzer, Michael Mansuy, Isabelle Poirazi, Panayiota Trouche, Didier Baum, Buzz Gönczy, Pierre Manzanares, Miguel Posas, Francesc Trumpp, Andreas Behrens, Axel Gonzalez-Reyes, Acaimo Marin, Oscar R Radtke, Freddy Tuschl, Thomas Beja, Oded H Hajnal, Alex Martin-Bermudo, Reich , Ziv U Uhlmann, Frank Berger, Frederic Hassan, Bassem Maria Dolores Robinson, Robert Ulrich, Helle Bertolotti, Anne Haucke, Volker Mattevi, Andrea Rodriguez, Ivan Ungermann, Christian Bertrand, Edouard Helariutta, Ykä Mehlen, Patrick S Salecker, Iris V van Aalten, Daan Blazquez, Miguel Helms, Volkhard Meier, Pascal Santos, Manuel Van den Ackerveken, Guido Bochtler, Matthias Hidalgo, Alicia Mitchell, Kevin Saudou, Frédéric van der Goot, Gisou Briscoe, James Hirst, Judy Moller, Simon Geir Schärer, Orlando D. van Steensel, Bas Bujnicki, Janusz Holstege, Frank Mosialos, George Schedl, Andreas Vinkemeier, Uwe C Casares, Fernando Hopfner, Karl-Peter Mota, Maria Schleper, Christa Voinnet, Olivier Christoforidis, Savvas J Jansen, Ralf Musacchio, Andrea Schlötterer, Christian W Wimmer, Ernst A. Collinson, Ian Jensen, Torben Heick N Nagy, Laszlo Schneitz, Kay Wutz, Anton Conradt, Barbara K Khakh, Baljit Nehrbass, Ulf Schwappach, Blanche Z Zeeman, Samuel Cosma, Maria Pia Knoblich, Jürgen Neuhauss, Stephan Spahn, Christian Zernicka-Goetz, Magdalena

www.embo.org/yip | [email protected] ➔ 107 EMBO young investigators: statistics

applications and awards 2000 2001 2002 2003 2004 2005 2000 – 2005 country appl. aw. appl. aw. appl. aw. appl. aw. appl. aw. appl. aw. Austria 9 5 3 0 1 0 0 0 3 1 3 1 Belgium 8 0 2 0 3 0 2 1 1 0 3 0 Croatia 2 0 1 0 0 0 0 0 1 0 1 0 Czech Republic 2 0 0 1 6 0 14 0 4 0 2 0 Denmark 5 1 0 0 0 0 2 2 0 0 1 0 Finland 9 2 1 0 4 1 3 0 9 0 2 0 France 72 5 17 4 26 4 26 2 17 3 14 2 Germany 52 7 22 4 17 4 15 3 30 3 23 4 Greece 8 2 1 2 4 1 3 0 4 1 6 0 Hungary 2 1 1 0 6 0 7 1 5 0 1 0 Iceland 0 0 0 0 0 0 1 0 0 0 0 0 Ireland 6 0 3 0 0 0 0 0 3 1 1 0 Israel 13 2 7 1 4 0 5 1 5 0 3 1 Italy 22 1 6 3 14 3 11 1 14 0 14 1 Netherlands 10 2 6 2 3 0 4 0 3 1 5 1 Norway 2 0 1 0 1 0 1 0 0 0 0 0 Poland 13 1 2 0 8 1 6 0 8 1 2 0 Portugal 9 1 6 1 2 0 2 1 3 0 4 0 Slovenia 3 0 0 0 0 0 0 0 1 0 2 0 Spain 40 4 26 1 18 2 26 2 21 1 17 1 Sweden 23 1 3 0 15 0 7 1 8 0 3 1 Switzerland 21 6 11 3 12 3 5 1 8 1 8 3 Turkey 8 0 1 0 2 0 2 0 1 0 0 0 United Kingdom 75 14 30 1 23 4 21 5 20 7 13 2 Others 1 0 0 0 0 0 0 0 3 0 0 0 total 415 55 150 23 169 23 163 21 172 20 128 17

Female 94 13 44 4 45 4 47 7 39 4 32 2 Male 321 42 106 19 124 19 116 14 133 16 96 15

➔ 108 young investigators: statistics

average general statistics for all young investigators age 34.7 selected 2000 – 2005 post-doctoral years 5.0 total number of publications 20.3 last-author publications 3.1 fi rst-author publications 9.2

no. % of total pre- and/or post-doctorate spent in USA USA 104 65.0

no. % of total post-doctoral fellowships received EMBO 48 31.0 from international agencies HFSP 34 21.4 EU TMR 19 12.0

www.embo.org/yip | [email protected] ➔ 109 EMBO young investigator lectures 2005

young investigator Zoi Lygerou 5th ISREC Conference: CH – Lausanne 18 – 22 January lectures 2005 Cell and Molecular Biology of Cancer Santiago Elena 10th Workshop of Plant Virology FR – Aussois 6 – 10 March

Karim Labib ICGEB 2005 Workshop: IT – Triest 2 – 5 May Chromosome duplication and segregation Bas van Steensel Alan Wolffe EMBO Conference DE – Heidelberg (EMBL) 19 – 22 May “Chromatin and Epigenetics” Nektarios Tavernarakis 25th Blankanese Conference: DE – Hamburg 21 – 25 May Signalling in Sensory Systems Olivier Voinnet Post-Transcriptional Regulation of US – Austin 8 – 12 June Plant Gene Expression (PTROPGE) Janusz Bujnicki 30th FEBS Congress and HU – Budapest 2 – 8 July 9th IUBMB Conference, The Protein World Stephane Noselli 30th FEBS Congress and HU – Budapest 2 – 8 July 9th IUBMB Conference, The Protein World Isabelle Mansuy 30th FEBS Congress and HU – Budapest 2 – 8 July 9th IUBMB Conference, The Protein World Frédéric Saudou Gordon Research Conference: US – New London 10 – 15 July Motile and Contractile Systems Mansuy, Isabelle Europhosphatases 2005: UK – Cambridge 10 – 14 July The Biology of Phosphatases Massimo Delledonne Nitric Oxide Signalling: ES – Barcelona 14 – 15 July Plant Growth and Development (Annual Meeting of the Society for Experimental Biology) Bruno Antonny BioScience 2005: From genes to systems UK – Glasgow 17 – 21 July

Buzz Baum BioScience 2005: From genes to systems UK – Glasgow 17 – 21 July

Volker Haucke BioScience 2005: From genes to systems UK – Glasgow 17 – 21 July

➔ 110 young investigator lectures 2005

young investigator Janusz Bujnicki MCCMB’05: RU – Moscow 18 – 21 July lectures 2005 2nd Moscow Conference on cont. Computational Molecular Biology Olivier Voinnet EMBO Workshop: Mechanisms and CH – Arolla 28 August – Regulation of mRNA Turnover 1 September Helle Ulrich 9th International Conference on US – San Francisco 3 – 8 September Environmental Mutagens Anne Spang ELSO 2005 DE – Dresden 4 – 6 September

Torben Heick Jensen ELSO 2005 DE – Dresden 4 – 6 September

Edouard Bertrand ELSO 2005 DE – Dresden 4 – 6 September

Maria Pia Cosma ELSO 2005 DE – Dresden 4 – 6 September

Facundo Batista ELSO 2005 DE – Dresden 4 – 6 September

Pascal Meier 30th European Symposium on FR – Mont Sainte Odile 15 – 18 September Hormones & Cell Regulation: Cell Death & Disease Benjamin Nichols ESF Research Conference: ES – San Feliu de Guixols 17 – 22 September Membrane Dynamics in Endocytosis Daniel Davis NK Hawaii: Natural killer cells and US – Hawaii 4 – 8 November innate immunity Andreas Trumpp EMBO Conference: IT – Milan 10 – 12 November International Workshop on Cancer Stem Cells Manuel Santos ESF-EMBO Symposium: ES – San Feliu de Guixols 12 – 17 November Comparative Genomics of Eukaryotic Microorganisms Janusz Bujnicki 21st tRNA workshop IN – Bangalore 2 – 7 December

Anne Spang 45th Annual Meeting of US – San Francisco 10 – 14 December the American Society for Cell Biology

www.embo.org/yip | [email protected] ➔ 111 EMBO courses | workshops | conferences | symposia 2005

practical courses 2005 Functional genomics: P. Ricciardi-Castagnoli IT – Milan 14 – 19 February Europe (EMBC) Making sense out of transcriptomes et al. From mice to cells L. Minichiello IT – Monterotondo (EMBL) 13 – 20 March et al. Optical techniques for cell physiology W.B. Amos UK – Plymouth 30 March – 9 April and developmental biology et al. Analysis and informatics of A. Brazma UK – Hinxton (EMBL-EBI) 4 – 9 April microarray data et al. Quantifi cation of gene expression by V. Benes DE – Heidelberg (EMBL) 28 May – 2 June real-time qRT-PCR et al. Light microscopy in living cells N. Moreno PT – Oeiras 9 – 17 June G. Cox Microinjection and detection of R. Pepperkok DE – Heidelberg (EMBL) 13 – 19 June probes in cells et al. Exploiting anomalous scattering in W. Shepard et al. FR – Grenoble (EMBL) 15 – 21 June macromolecular structure determination (Joint ESRF/EMBL/EMBO Course) BioXAS on metalloproteins and W. Meyer-Klaucke DE – Hamburg (EMBL) 14 – 19 June organism tissue S. Mangani Advanced techniques in U. Landegren SE – Uppsala 15 – 22 June molecular medicine et al. (Joint EU/EMBO Course) Microarray technology: C. Schwager DE – Heidelberg (EMBL) 20 – 25 June From production to systems biology et al. Electron microscopy and stereology J. Nebesarova CZ – Ceske Budejovice 21 – 30 June in cell biology et al. High-throughput methods for C. Cambillau FR – Marseille 4 – 13 July protein production and crystallisation et al. Enhancer detection, gene trapping T. Becker NO – Bergen 1 – 11 August and TILLING in zebrafi sh et al. SNP genotyping and L. Peltonen FI – Helsinki 21 – 27 August haploblock analysis et al.

➔ 112 courses | workshops | conferences | symposia 2005

practical courses 2005 Methods in cell biology: D. Brunner DE – Heidelberg (EMBL) 22 August – 2 September Europe (EMBC) cont. From single molecule to complex T. Surrey systems analysis Image processing for E. Orlova UK – London 4 – 14 September cryo-electron microscopy H. Saibil Endocytosis and signalling during M. Gonzalez DE – Dresden 4 – 15 September development et al. Structure determination of biological S. Grzesiek CH – Basel 7 – 14 September macromolecules by solution NMR et al. (Joint Biozentrum/EMBO Course) Combination of electron microscopy J. Navaza FR – Gif-sur-Yvette 23 – 28 October and X-ray crystallography in structure et al. determination practical courses 2005 RNAi and reverse genetics in C. Clayton GH – Accra 10 – 21 January outside Europe trypanosomes et al. (Joint TDR/EMBO Course) Advanced optical methods in S. Ahmed SG – Singapore 17 – 28 January cell and developmental biology E. Stelzer (Joint BMRC/EMBO Course) et al. Structural and evolutionary genomics. G. Bernardi CR – San Jose 26 February – 2 March Genome and RNA: Expression and functions et al. (Joint ICRO/UNESCO/EMBO Course) Bioinformatics and genome data analysis H. Ayadi TN – Sfax 24 March – 2 April (Joint Pasteur Institut/ICGEB/ ICRO/ A. Rebai UNESCO/IUBMB/EMBO Course) F. Tekaia Malaria functional genomics B. Crabb IN – New Delhi 9 – 21 October (Joint TDR/HHMI/EMBO Course) et al. Genomics, proteomics and bioinformatics J.E. Allende CL – Santiago 11 – 23 October (Joint ICRO/UNESCO/EMBO Course) et al. Calcium signalling, with special attention J.R. Sotelo UY – Montevideo 16 – 29 October to cell motility and the cytoskeleton et al. (Joint ICRO/UNESCO/EMBO Course)

www.embo.org/courses_workshops | [email protected] ➔ 113 EMBO courses | workshops | conferences | symposia 2005

practical courses 2005 Functional microscopy of G. Griffi ths ZA – Cape Town 18 – 30 November outside Europe cont. host pathogen interactions et al. Microarray technology: L.M. Teran MX – Mexico DF 20 – 26 November Production and applications et al.

lectures courses 2005 Channels and transporters L. DeFelice IT – Erice, Sicily 31 May – 6 June Europe (EMBC) B. Kanner Cellular and molecular biology of A.P. Pugsley FR – Cargèse, 20 June – 1 July membranes (Joint FEBS/EMBO Course) et al. Corsica Molecular mechanisms in J.L. Bos GR – Spetses 15 – 26 August signal transduction and cancer et al. (Joint FEBS/EMBO Course) Protein misfolding, protein modifi cation A. Fersht GR – Spetses 5 – 15 September and age-related diseases et al. (Joint FEBS/EMBO Course) Mouse models for human disease J. Auwerx FR – Bischoffsheim 17 – 23 September P. Chambon et al.

workshops 2005 The road ahead: E. Vivier FR – Marseille 13 – 15 January Europe (EMBC) Future directions in fundamental et al. and clinical immunology Meiotic divisions and checkpoints C. Jessus FR – Cargèse, 16 – 20 March et al. Corsica mRNA 3’ Ends: N.J. Proudfoot UK – Oxford 17 – 19 March Interconnections with transcription, J.L. Manley translation and mRNA turnover Structural basis of P. Amati IT – Siena 11 – 16 April papovavirus biology et al. Notch signalling in development I. Screpanti IT – Rome 21 – 24 April and cancer et al.

➔ 114 courses | workshops | conferences | symposia 2005

workshops 2005 RNA control of neuronal function J. Yisraeli IL – Kfar Blum, 22 – 26 May Europe (EMBC) cont. et al. Upper Galilee Plant stem cells: C. Gutiérrez ES – Madrid 23 – 25 May Independent inventions and conserved et al. mechanisms (Joint Juan March/EMBO Workshop) Invasive growth: P.M. Comoglio IT – Candiolo (Torino) 26 – 29 May A genetic program for stem cells, et al. cancer and cancer stem cells Biology of molecular chaperones. M. Zylicz˙ PL – Zakopane 28 May – 2 June Heat shock proteins in molecular F.U. Hartl medicine: Misfolding diseases and cancer (Joint FEBS/EMBO Workshop) Molecular and population biology of K. Louis GR – Kolymbari, Crete 24 – 31 July mosquitoes and other disease vectors et al. Regulation of mRNA turnover C. Moroni CH – Arolla 28 August – 1 September et al. Chromosome dynamics and J.L. Santos ES – Madrid 13 – 18 September recombination in meiosis et al. Membrane dynamics in endocytosis M.S. Robinson ES – San Feliu de Guixols 17 – 22 September (Joint FEBS/ESF/EMBO Workshop) H. Riezman Cytoskeletal molecular motors J. Kendrick Jones UK – Cambridge 18 – 22 September (Joint 61st Harden conference/ R. Cross EMBO Workshop) F. Buss The molecular and cellular M. Buckingham FR – Fontevraud 24 – 29 September mechanisms underlying skeletal J. Melki muscle formation and repair L. Schaeffer (Joint FEBS/EMBO Workshop) Centrosomes and spindle pole bodies M. Knop DE – Heidelberg (EMBL) 23 – 27 September et al. The assembly and function of P. Caroni CH – Ascona 25 – 30 September neuronal circuits et al.

www.embo.org/courses_workshops | [email protected] ➔ 115 EMBO courses | workshops | conferences | symposia 2005

workshops 2005 Chromosome structural elements: F. Ascenzioni IT – Rome 29 September – 3 October Europe (EMBC) cont. From DNA sequence to function et al. Frontiers of molecular biology M. Zylicz˙ PL – Warsaw 14 – 18 October (EMBO Members Workshop) et al. Principles of self-organisation in P. Bastiaens DE–Heidelberg (EMBL) 4 – 7 November living matter et al.

workshops 2005 Innate immunity in the lung S. Gordon ZA – Cape Town 30 November – 2 December outside Europe (Joint Novartis Foundation/Medical G. Brown Research Council/EMBO Workshop) Molecular physiology of R. Padinjat IN – Coorg 30 November – 4 December intracellular calcium signalling et al. Upstream and downstream of R.K. Mishra IN – Hyderabad 14 – 17 December Hox genes F. Karch

conferences 2005 Chromatin and epigenetics. G. Almouzni DE – Heidelberg (EMBL) 19 – 22 May Europe (EMBC) Alan Wolffe EMBO Conference et al. (Joint EU/EMBO Conference) Helicases and NTP-driven nucleic acid P. Linder CH – Arolla 5 – 10 July machines: structure, function and roles S. Kowalczykowski in human disease (Joint SNSF/EMBO Conference) The biology of phosphatases D. Alexander UK – Cambridge 10 – 14 July et al. Ciliate molecular biology T. Clark IT – Il Ciocco, Lucca 3 – 8 August (Joint FASEB/EMBO Conference) C. Miceli J. van Houten PSEUDOMONAS 2005: A. Filloux FR – Marseille 27 – 31 August A multidisciplinary exploration of et al. current Pseudomonas research (Joint FEMS/EMBO Conference) Protein synthesis and M. Hentze DE – Heidelberg (EMBL) 13 – 18 September translational control et al.

➔ 116 courses | workshops | conferences | symposia 2005

conferences 2005 Nuclear structure and dynamics G. Cavalli FR – La Grande Motte 24 – 28 September Europe (EMBC) cont. et al. Nuclear receptors: J. Schwabe IT – Lake Garda 29 September – 1 October From chromatin to disease et al. joint EMBO/ESF Three-dimensional sensory and motor D. Wolpert ES – San Feliu de Guixols 8 – 13 October symposia 2005 space: Probabilistic mechanisms of learning et al. and development in sensorimotor systems Probing the molecular basis of M. Engelhard ES – San Feliu de Guixols 29 October – 3 November protein function through chemistry: et al. Scope of chemical protein synthesis Comparative genomics of eukaryotic J.-L. Souciet ES – San Feliu de Guixols 12 – 17 November microorganisms: Eukaryotic genome et al. evolution, approaches with yeasts and fungi

www.embo.org/courses_workshops | [email protected] ➔ 117 EMBO plenary lectures 2005

plenary Philip Cohen The Annual Membership Meeting of NO – Tromö 13 – 16 January lectures 2005 the Norwegian Biochemistry Society 2005 Europe (EMBC) Denis Duboule British Society for Developmental Biology/ UK – Warwick 6 – 9 April British Society for Cell Biology Spring Symposium Matthias Hentze First Congress of the International BioIron CZ – Prague 22 – 27 May Society (IBIS) Fotis Kafatos From Gene to Genome: FR – La Grande Motte 26 – 28 May Heredity and Society Howy Jacobs International Conference on Plant FR – Obernai 28 May – 2 June Mitochondrial Biology Maciej Zylicz˙ ESHO Symposium AT – Graz 8 – 11 June Raymond Dwek FEBS-IUBMB Satellite Meeting RO – Bucharest 28 June – 2 July Protein Folding and Transport in Health and in Disease Maria Carmo-Fonseca 2005 FEBS-IUBMB Congress: HU – Budapest 2 – 7 July The Protein World Matthias Mann BioScience 2005: UK – Glasgow 17 – 21 July From Genes to Systems David Baulcombe XVII International Botanical Congress AT – Vienna 17 – 23 July Nikolaus Pfanner XXII International Conference on SK – Bratislava 7 – 12 August Yeast Genetics and Molecular Biology Moshe Oren 3rd International MDM 2 Workshop DE – Konstanz 9 – 12 September Tom Blundell MGMS International Meeting 2005 IE – Dublin 11 – 14 September Biomolecular Simulations: From prediction to practice Peter Cresswell International Meeting on the DE – Heidelberg 18 – 21 September Molecular Biology of Hepatitis B Viruses Anthony Hyman 7th FISV Meeting IT – Riva del Garda 22 – 25 September John Gurdon Stem Cells in Basic and Medical Research DK – Fyn 24 – 26 October Ron Laskey 7th International EMBL PhD Symposium DE – Heidelberg 1 – 3 December Biology at Work

➔ 118 plenary lectures 2005

plenary David Baltimore 3rd Annual Africa Genome KE – Nairobi 25 – 28 March lectures 2005 Initiative Conference outside Europe A Time to Heal: The science of and investments in cracking Africa’s killer diseases Alan Hall The Hunter Cellular Biology Meeting AU – Hunter Valley 6 – 8 April Jules Hoffmann Gordon Research Conference: US – Rhode Island 7 – 12 August Molecular Mechanisms of Microbial Adhesion and Signalling Steve Cohen International Society of Biologists AU – Sydney 3 – 7 September 15th Congress: From egg to adult – constructing the complexity of life Gerd Jürgens Buenos Aires Plant Biology Lectures, AR – Buenos Aires 24 – 26 October Series 2005 Anthony Hyman 8th A-IMBN conference VN – Ho Chi Minh City 27 – 29 October Jean Marc Egly XX Annual meeting of the Argentine AR – Buenos Aires 3 – 6 December Society for Neurochemistry and the X Congress of the Panamerican Association of Biochemistry and Molecular Biology Jens Stougaard XII International Congress on MX – Cancun 14 – 18 December Molecular Plant Microbe Interactions

www.embo.org/about_embo/lectures.html | [email protected] ➔ 119 EMBO participation of women in EMBO activities: statistics

participation of women in EMBO activities

EMBO membership EMBO members % women 2001 1092 12.9 2002 1126 13.1 2003 1162 13.3 2004 1191 13.7 2005 1223 13.8

EMBO courses & workshops % female participants % female speakers 2001 practical courses 44 23 workshops 40 26 lecture courses 63 20

2002 practical courses 51 23 workshops 39 25 lecture courses 58 19

2003 practical courses 49 22 workshops 41 24 lecture courses 48 13

2004 practical courses 56 27 workshops 40 25 conferences 40 21 lecture courses 50 29

2005 practical courses 53 27 workshops 41 22 conferences 40 26 lecture courses 60 25

➔ 120 participation of women in EMBO activities: statistics

EMBO long-term fellowships applications awards % success rate 1996 – 2001 female applicants 1914 (40.8 %) 347 (35.0 %) 18.1 male applicants 2772 (59.2 %) 644 (65.0 %) 23.2 total 4686 991 21.1

2002 female applicants 347 (43.4 %) 68 (40.5 %) 19.5 male applicants 453 (56.6 %) 100 (59.5 %) 22.1 total 800 168 21.0

2003 female applicants 469 (43.4 %) 64 (36.4 %) 13.6 male applicants 611 (56.6 %) 112 (63.6 %) 18.3 total 1080 176 16.3

2004 female applicants 533 (46.9 %) 65 (39.9 %) 12.2 male applicants 604 (53.1 %) 98 (60.1 %) 16.2 total 1137 163 14.3

2005 female applicants 589 (47.7 %) 89 (44.9 %) 15.1 male applicants 647 (52.3 %) 109 (55.1 %) 16.8 total 1236 198 16.0

1996 – 2005 female applicants 3852 (42.4 %) 633 (37.3 %) 16.4 male applicants 5087 (57.6 %) 1063 (62.7 %) 20.9 total 8939 1696 19.0

www.embo.org/gender | [email protected] ➔ 121 EMBO participation of women in EMBO activities: statistics

EMBO short-term fellowships applications awards % success rate 2001 female applicants 130 (55.7 %) 70 (56.4 %) 53.8 male applicants 103 (44.2 %) 54 (43.5 %) 52.4 total 233 124 53.2

2002 female applicants 148 (53.4 %) 81 (53.3 %) 54.7 male applicants 129 (46.6 %) 71 (46.7 %) 55.0 total 277 152 54.9

2003 female applicants 139 (53.7 %) 72 (52.2 %) 51.8 male applicants 120 (46.3 %) 66 (47.8 %) 55.0 total 259 138 53.3

2004 female applicants 161 (53.7 %) 84 (52.2 %) 52.2 male applicants 140 (46.3 %) 83 (47.8 %) 59.3 total 301 167 55.5

2005 female applicants 190 (49.6 %) 88 (44.0 %) 46.3 male applicants 193 (50.4 %) 112 (56.0 %) 58.0 total 383 200 52.2

2001 – 2005 female applicants 768 (52.8 %) 395 (50.6 %) 51.4 male applicants 685 (47.1 %) 386 (49.4 %) 56.4 total 1453 781 53.8

➔ 122 participation of women in EMBO activities: statistics

EMBO young investigators applications awards % success rate 2000 – 2001 female applicants 138 (24.4 %) 17 (21.8 %) 12.3 male applicants 427 (75.6%) 61 (78.2 %) 14.3 total 565 78 13.8

2002 female applicants 45 (26.8 %) 4 (17.4 %) 8.9 male applicants 123 (73.2 %) 19 (73.8 %) 15.4 total 168 23 13.8

2003 female applicants 47 (28.8 %) 7 (33.3 %) 14.8 male applicants 116 (71.2 %) 14 (66.7 %) 12.1 total 163 21 12.8

2004 female applicants 38 (22.1 %) 4 (20.0 %) 10.5 male applicants 134 (77.9 %) 16 (80.0 %) 11.9 total 172 20 11.6

2005 female applicants 32 (25.0 %) 2 (11.8 %) 6.3 male applicants 96 (75.0 %) 15 (88.2 %) 15.6 total 128 17 13.3

2000 – 2005 female applicants 300 (25.1%) 34 (21.4 %) 11.3 male applicants 896 (74.9 %) 125 (78.6 %) 14.0 total 1196 159 13.3

www.embo.org/gender | [email protected] ➔ 123 EMBO staff

Eilish Craddock (left), personal secretary to Frank Gannon Gitta Bourke and Agnès Visser-de Matteïs is the administrator for EMBC, work in the Executive Director’s offi ce. located in the EMBO building.

Executive Director’s Offi ce Frank Gannon EMBO Executive Director [email protected] EMBC Secretary General Eilish Craddock Personal Secretary to Frank Gannon [email protected] Agnès Visser-de Matteïs Administrator [email protected] Pirkko Kokkosalo** Administrator

EMBC Gitta Bourke Administrator [email protected]

EMBO Council and Membership Claudia Hagedorn Administrator [email protected]

Courses & Workshops Programme Mary Gannon Programme Manager [email protected] [email protected] Zeynep Dinsi-Yararli Administrator [email protected] World Activities Lynne Turnbull Administrator, Online HelpDesk [email protected] [email protected] Felise Fortmann** Administrator Kathy Oswald** Administrator

Electronic Information Programme Les Grivell Programme Manager [email protected] [email protected] Ole Hansen Technical Offi cer [email protected] Patricia Codyre* Communications Offi cer (Web) [email protected] Anne Seller Administrator [email protected] Sabine Rehberger-Schneider Life Sciences Mobility Consultant [email protected] Laura Cortesi Data Manager [email protected]

Fellowship Programme Jan Taplick Programme Manager [email protected] [email protected] Liselott Maidment Administrator (long-term fellowships) [email protected] Agnès Visser-de Matteïs Administrator (short-term fellowships) [email protected]

Science & Society Programme Andrew Moore Programme Manager [email protected] [email protected] Alessandra Bendiscioli Administrator [email protected]

Young Investigator Programme Gerlind Wallon Programme Manager [email protected] [email protected] Kim Krynauw Administrator [email protected] Women in the Life Sciences [email protected]

Finances Bernhard Huber Financial Manager [email protected] Bärbel Traut-Laur Administrator [email protected]

* started at EMBO in 2005 ** left EMBO in 2005 or prior to March 2006

➔ 124 staff

Kerstin Hiester Seán Bourke organises travel at EMBO welcomes visitors at the EMBO reception desk and and assists with meetings. takes care of building matters.

The EMBO Journal Pernille Rørth* Executive Editor [email protected] [email protected] Isabel Arnold* Editor [email protected] Karin Dumstrei* Editor [email protected] Valerie Ferrier (Co-ordinator) Editor [email protected] Thomas Lemberger* Editor [email protected] Volker Wiersdorff Editor [email protected] Astrid Lunkes** Editor Frank Gannon Associate Editor [email protected] Jana Christopher* Editorial Assistant [email protected] Fiona Panayi Editorial Assistant [email protected] Karen Thompson Editorial Assistant [email protected] Claire Johnstone** Editorial Assistant Sophia Katsogiannos** Editorial Assistant

EMBO reports Frank Gannon Senior Editor [email protected] [email protected] Holger Breithaupt Science & Society Editor [email protected] Sandra Caldeira* Scientifi c Reports Editor [email protected] Caroline Hadley (Co-ordinator) Assistant Editor [email protected] Susan Owens Reviews Editor [email protected] Christine Blaumueller** Scientifi c Reports Editor Les Grivell Associate Editor [email protected] Uta Mackensen Graphics Editor [email protected] Caroline Simpson Editorial Assistant [email protected]

Molecular Systems Biology Thomas Lemberger* Editor [email protected] [email protected] Astrid Lunkes** Editor Les Grivell Associate Editor [email protected] Frank Gannon Associate Editor [email protected] Jana Christopher* Editorial Assistant [email protected] Caroline Simpson Editorial Assistant [email protected]

Communications Offi ce Lindsay Johnson Chief Communications Offi cer [email protected] [email protected] Uta Mackensen Graphic Designer [email protected] Anne Seller Administrator [email protected]

Reception and Building Maintenance Seán Bourke Administrator [email protected]

Meetings and Travel Arrangements Kerstin Hiester Administrator [email protected]

European Life Sciences Forum (ELSF) Luc Van Dyck Executive Co-ordinator [email protected] www.embo.org ➔ 125 EMBO title

EVENTS 2006

➔ 126 www.embo.org | [email protected] EMBO | EMBC events in 2006

practical courses pages 128 – 129

lecture courses page 130

workshops pages 130 – 132

conference series page 132

conferences page 133

ESF-EMBO symposia page 133

plenary lectures pages 134 – 135

other EMBO events pages 136 – 137

➔ 127 EMBO courses | workshops | conferences | conference series | symposia 2006

practical courses 2006 Chromatin immunoprecipitation G. Reid, R. Metivier DE – Heidelberg 27 February – 4 March Europe (EMBC) S. Denger, F. Gannon Comparative genomics and L. Mullan ES – Valencia 19 – 21 April SNP analysis using the Ensembl Genome Browser Statistical methods for C. Schlötterer FI – Helsinki 15 – 19 May the identifi cation of genes under et al. natural selection Structural characterisation of C.W. Müller FR – Grenoble 15 – 20 May macromolecular complexes et al. Molecular genetics with the fi ssion yeast O. Nielsen DK – Copenhagen 11 – 21 June Schizosaccharomyces pombe Advanced techniques in U. Landegren SE – Uppsala 13 – 20 June molecular medicine Quantifi cation of gene expression V. Benes DE – Heidelberg 17 – 23 June by qPCR Plant cell biology A.M. Emons NL – Wageningen 18 – 24 June The application of transient kinetics M.A. Geeves UK – Canterbury 18 – 24 June methods to biological macromolecules Electron microscopy and stereology in N. Roos NO – Oslo 20 – 29 June cell biology et al. (Joint FEBS/EMBO Course) Advanced analysis and informatics of A. Brazma UK – Hinxton 25 June – 1 July microarray data Microinjection and detection of R. Pepperkok DE – Heidelberg 25 June – 1 July probes in living cells Biomolecular simulation M. Nilges FR – Paris 28 June – 5 July Flow cytometry and cell sorting A. Radbruch DE – Berlin 16 – 21 July Cryo-electron microscopy and B. Böttcher DE – Heidelberg 13 – 22 August 3-D image analysis Genome, transcriptome and A. Bosio DE – Cologne 27 August – 1 September miRNome analysis of single cells

➔ 128 courses | workshops | conferences | conference series | symposia 2006

practical courses 2006 Multidimensional NMR in C. Griesinger IT – Il Ciocco 27 August – 1 September Europe (EMBC) cont. structural biology Development and evolution of C. Nüsslein-Volhard DE – Tübingen 28 August – 8 September animals and plants et al. Protein expression, purifi cation and P.A. Tucker DE – Hamburg 28 August – 5 September crystallisation (PEPC5) Working with stem cells P. Andrews UK – Sheffi eld 30 August – 6 September Ubiquitin and SUMO I. Dikic HR – Split 5 – 11 September Anatomy and embryology of A. Marusic HR – Zagreb 9 – 17 September the mouse Molecular approaches to evolution D. Arendt IT – Naples 11 – 22 September and development in co-operation with et al. ZOONET (Marie Curie Research Training Network) Bioinformatics for mass spectrometry P.A. Binz CH – Geneva 18 – 22 September in proteomics P. Palagi M.C. Blatter Molecular genetics of J.D. Rochaix CH – Geneva 18 – 29 September Chlamydomonas et al. Multi-photon imaging of A. Konnerth DE – Munich 22 – 28 October living cells and tissues Solution scattering from D. Svergun DE – Hamburg October biological macromolecules practical courses 2006 Advanced methods in reconstructing T.M. Embley BR – Rio de Janeiro 13 – 19 March outside Europe molecular phylogenetic relationships Proteins as cellular nanomachines: L.C. Cameron BR – Rio de Janeiro 8 – 19 May Molecular motors, channels & pumps (III. International Symposium on Myosin V) PROTEINS: F. Gräter CN – Shanghai 10 – 17 May Structure, dynamics and energetics

www.embo.org/courses_workshops | [email protected] ➔ 129 EMBO courses | workshops | conferences | conference series | symposia 2006

practical courses 2006 Advances in technologies for high T.M. Jovin AR – Buenos Aires 6 – 18 August outside Europe cont. resolution in vivo microscopy: From single molecule detection to functional studies Genetic manipulation and C. Clayton KE – Nairobi 27 November – RNA interference in African trypanosomes et al. 16 December (Joint WHO-TDR/EMBO Course)

lecture courses 2006 Molecular and cellular cognition R. Brambilla IT – Venice 1 – 6 July Europe (EMBC) Molecular mechanisms of development I. Kramer ES – Barcelona 2 – 7 July et al. Molecular basis of bacterial virulence P. Cossart GR – Spetses 5 –15 September and survival within infected hosts and et al. in the environment (Joint FEBS/FEMS/EMBO Course) Fundamentals of modern methods of M.A. Carrondo PT – Oeiras 6 –13 October biocrystallography (Joint FEBS/EMBO Course)

workshops 2006 Innate danger signals and HMGB1 M. Bianchi IT – Milan 8 –11 February Europe (EMBC) et al. Transcriptional regulation in J. Weitzman FR – Paris 6 – 8 March health and disease et al. Homeodomain proteins, haematopoietic F. Blasi IT – Riva del Garda 23 – 25 March development and leukaemias et al. (Joint SEMM/EMBO Workshop) Structure, mechanism of formation and F. Chiti IT – Florence 25 – 28 March cellular effects of amyloid aggregates et al. (Joint FEBS/EMBO Workshop) The nucleolus: New perspectives J.A. Hiscox UK – York 28 – 29 March et al.

➔ 130 courses | workshops | conferences | conference series | symposia 2006

workshops 2006 NO: A radical in control. The biological V. O’Donnell UK – Cirencester 4 – 8 April Europe (EMBC) cont. diversity of nitric oxide metabolism et al. and signalling (Joint 62nd Harden Conference/ EMBO Workshop) Redox signalling in T. Galeotti IT – Rome 20 – 23 April human disease and ageing et al. Functional organisation of I. Raska CZ – Prague 5 – 8 May the cell nucleus et al. Signals and mechanics in P. Rørth DE – Heidelberg 18 – 20 May directed cell migration Evolutionary biology of H. Teotónio PT – Oeiras 23 – 27 May Caenorhabditis elegans and closely related species Principles of self-organisation in P. Bastiaens DE – Heidelberg 2 – 5 June living matter E. Karsenti Cell membrane organisation K. Simons ES – Bilbao 3 – 7 June and dynamics et al. Plant virology 2006: J. Valkonen FI – Haikko 1 – 5 July Suppression and circumvention of host defence by plant viruses The genomics of development D. Duboule CH – Arolla 21 – 26 August et al. Cell cycle and cytoskeletal A. Løbner-Olesen DK – Copenhagen 23 – 27 August elements in bacteria et al. Stemness: The bright and the dark side. G. Morrone IT – Catanzaro 20 – 22 September Normal and cancer stem cells Spatial and temporal K. Tasken NO – Oslo 21 – 24 September regulation of signalling (Joint FEBS/EMBO Workshop) Hedgehog-Gli signalling in A. Gulino IT – Rome 30 September – 4 October cancer and stem cells

www.embo.org/courses_workshops | [email protected] ➔ 131 EMBO courses | workshops | conferences | conference series | symposia 2006

workshops 2006 Systems biology meets D.A. Jackson AT – Gosau 12 – 15 October Europe (EMBC) cont. chromatin function Frontiers of molecular biology P. Ingham UK – Sheffi eld 13 – 16 October (EMBO Members Workshop) Cell migration, tissue invasion and disease M.P. Stoppelli IT – Capri 14 – 17 October Programming pancreatic β-cells J. Ferrer ES – El Perello, Tarragona 18 – 22 October (Joint FEBS/EMBO Workshop) F.X. Real P. Herrera Systems dynamics of intracellular M. Fainzilber IL – Ein Gedi 29 October – 2 November communication – overcoming distance in signalling networks (Joint FEBS/EMBO Workshop)

conference series 2006 Oncogenes and growth control S. Cohen DE – Heidelberg 26 – 30 April Europe (EMBC) P. Rørth Recombination mechanisms and the S. West FR – Seillac 15 – 19 May maintenance of genome stability Molecular and developmental biology of T. Kaufman GR – Kolymbari, Crete 18 – 24 June Drosophila et al. The molecular and cellular basis of B. Galliot CH – Ascona 10 –15 September regeneration and tissue repair et al. Macromolecular complexes in microbial H. Stenmark ES – San Feliu de Guixols 23 – 28 September pathogenesis, membrane traffi cking & et al. cell signalling Protein transport systems: J. Soll PL – Gdansk 30 September – 5 October Protein targeting and translocation The pathology of pre mRNA splicing: F.E. Baralle IT – Cortina d’Ampezzo 14 – 17 January 2007 Diagnostic and mechanistic aspects

➔ 132 courses | workshops | conferences | conference series | symposia 2006

conferences 2006 Common molecular mechanisms of W.M. Gallagher IE – Dublin 6 – 8 June Europe (EMBC) mammary gland development and breast cancer progression (Joint HBR/COST B20/EMBO Conference) Molecular and cell biology at Spetsai: B.F.C. Clark GR – Spetses 1 – 5 September Past, present and future – a forty year anniversary (Joint FEBS/EMBO Conference) Molecular microbiology: A.J. Carpousis DE – Heidelberg 19 – 23 October Dynamics, evolution and expression of prokaryotic genomes joint EMBO/ESF B cells cross the divide. From in silico to T. Defrance ES – San Feliu de Guixols 13 – 18 May symposia 2006 the whole person Gene transcription in yeast J. Mellor ES – San Feliu de Guixols 24 – 29 June Bacterial networks: Joining the strengths K.J. Hellingwerf ES – San Feliu de Guixols 2 – 7 September of structural and systems biology to reach ‘synthetic’ biology Stem cells in tissue engineering: R.L. Reis ES – San Feliu de Guixols 27 October – 1 November Isolation, culture, characterisation and applications

www.embo.org/courses_workshops | [email protected] ➔ 133 EMBO plenary lectures 2006

plenary Klaus-Armin Nave XXII International Winter Meeting of CH – St Moritz 22 – 26 March lectures 2006 the Swiss Society of Neuropathology: Europe (EMBC) Growth and death in the nervous system Harald Stenmark UK Biochemical Society Annual Symposium: UK – Birmingham 29 – 31 March The cell biology of inositol lipids and phosphates Ferenc Nagy International Plant Photobiology Meeting FR – Paris 24 – 28 April Rolf Kemler Transcriptional Regulation and Cancer TR – Ankara 3 – 5 May WilliamT. Wickner ASM-FEMS Conference on GR – Crete 6 –12 May Protein Traffi c in Prokaryotes Aaron Ciechanover FEBS Special Meeting: HR – Dubrovnik 26 May – 1 June Molecular Signalling David Baulcombe 3rd EPSO Conference: Plant Dynamics: HU – Visegrad 28 May – 1 June From Molecules to Ecosystems Stephen Cohen IMBA MicroSymposium on Small RNAs AT – Vienna 29 – 30 May Fotis C. Kafatos 31st FEBS Congress: TR – Istanbul 24 – 29 June Molecules in Health & Disease Aaron Ciechanover 2nd FEMS Congress of European ES – Madrid 4 – 8 July Microbiologists (Integrating Microbial Knowledge in Human Life) Detlef Weigel XV FESPB 2006 FR – Lyon 17 – 21 July Raymond A. Dixon 7th European Nitrogen Fixation Conference DK – Aarhus 22-26 July Michael D. Waterfi eld BioScience 2006: UK – Glasgow 23-27 July Bioscience for the 21st century Patricia Simpson First meeting of the European Society for CZ – Prague 17-19 August Evolutionary Developmental Biology Titia de Lange Telomeres and Genome Stability 2006 CH – Villars-sur-Ollon 30 August – 3 September Jonas Frisén EuroStemCell International Conference CH – Lausanne 8 –10 September Advances in Stem Cell Research René Bernards 3rd EMBL Biennial Symposium: DE – Heidelberg 14 –17 October From Functional Genomics to Systems Biology

➔ 134 plenary lectures 2006

plenary Nadia Rosenthal The 6th Hunter Cellular Biology Meeting AU – Hunter Valley 22 – 24 March lectures 2006 outside Europe Paul Nurse JR McIntosh Symposium: The molecular basis US – Colorado 23 – 24 June of motility and mitosis Tim Hunt QMB2006: 16th Annual Queenstown NZ – Queenstown 29 August – Molecular Biology Meeting 1 September “Molecular Biology of the Living Cell” Raymond A. Dwek 2006 International Hepatitis B Virus Meeting CD – Richmond 17 – 20 September Kurt Nordström Plasmid Biology 2006 US – South Lake Tahoe 23 – 27 September

www.embo.org/about_embo/lectures.html | [email protected] ➔ 135 EMBO other EMBO events 2006

fellowship Fellows Meeting (Europe) J. Taplick DE – Heidelberg (EMBL) 26 – 29 May programme A. Visser-de Matteïs Fellows Meeting (USA) J. Taplick US – San Diego 11 – 13 November L. Maidment

young investigator Laboratory Management Course G.Wallon DE – Heidelberg 29 – 31 March programme Part I (for EMBO Young Investigators) K. Krynauw Young Investigator Meeting G.Wallon AT – Vienna 3 – 6 May K. Krynauw EMBO/HHMI Central European G.Wallon HR – Dubrovnik 15 – 17 June Scientists Meeting K. Krynauw Laboratory Management Course G.Wallon DE – Heidelberg 19 – 22 June (open to all independent scientists) K. Krynauw Laboratory Management Course G.Wallon DE – Heidelberg 6 – 8 July Part II (for EMBO Young Investigators) K. Krynauw Young Investigator PhD Course G.Wallon DE – Heidelberg 17 – 24 September K. Krynauw Laboratory Management Course G.Wallon DE – Heidelberg 30 October – 3 November (open to all independent scientists) K. Krynauw Laboratory Management Courses G.Wallon DE – Heidelberg 28 – 30 September (for EMBO Fellows) K. Krynauw 4 – 6 November 8 – 10 November 30 November – 2 December

➔ 136 www.embo.org/fellowships | www.embo.org/yip other EMBO events 2006

science & society Focus Meeting on Stem Cell Research A. Moore DE – Heidelberg 19 April programme A. Bendiscioli 5th International Workshop on A. Moore DE – Heidelberg (EMBL) 11 – 13 May Secondary School Biology Education: A. Bendiscioli From School to University Media Workshop A. Moore DE – Heidelberg (EMBL) 27 May A. Bendiscioli Science Communication and Society A. Moore HR – Dubrovnik 31 May (FEBS Special Meeting on A. Bendiscioli Molecular Signalling) Fun and games with media communication A. Moore DE – Munich 17 July (Media Workshop at ESOF 2006) A. Bendiscioli Basic Research: Small and sexy A. Moore DE – Munich 18 July (Science & Society Session at ESOF 2006) A. Bendiscioli Media Communication Workshop A. Moore UK – Sheffi eld 14 October (Special Science & Society Session at A. Bendiscioli the EMBO Members Workshop) 7th EMBL/EMBO Joint Conference on H. Stefánsson DE – Heidelberg (EMBL) 3 – 4 November Science and Society: A. Moore Genes, brain/mind and behaviour A. Bendiscioli EMBC Special Hearing on A. Moore DE – Heidelberg (EMBL) 20 November Stem Cell Research A. Bendiscioli

www.embo.org/scisoc ➔ 137 organisations and acronyms

The following organisations are represented by their acronyms throughout this report:

ABI Adolf Butenandt Institute (Adolf-Butenandt-Institut) CICIC Scientifi c Research Centre of Isla de la Cartuja Munich, Germany (Centro de Investigaciones Científi cas Isla de la Cartuja) AFCRI Abramson Family Cancer Research Institute Seville, Spain Philadelphia, USA CIML Marseille Luminy Immunology Centre AMC Amsterdam Medical Center, University of Amsterdam (Centre d'Immunologie de Marseille Luminy) (Academisch Medisch Centrum, Universiteit van Amsterdam) France The Netherlands CLB Central Laboratory of Blood Transfusion BBSRC Biotechnology and Biological Sciences Research Council Amsterdam, The Netherlands Swindon, UK CMBI Centre for Molecular and Biomolecular Informatics BCM Baylor College of Medicine, Nijmegen, The Netherlands Houston, USA CMNS Consorzio Mario Negri Sud, BM:BWK Federal Ministry for Education, Science and Culture Santa Maria Imbaro (Chieti), Italy (Bundesministerium für Bildung, Wissenschaft und Kultur) CMU University of Geneva Medical Centre Vienna, Austria (Centre Médical Universitaire, Université de Genève) BMBF Federal Ministry of Education and Research Switzerland (Bundesministerium für Bildung und Forschung) CNB Spanish National Biotechnology Centre Bonn, Germany (Centro Nacional de Biotecnologia) BOKU University of Natural Resources and Applied Life Sciences Madrid, Spain (Universität für Bodenkultur) CNIC Spanish National Cardiovascular Centre Vienna, Austria (Centro Nacional de Investigaciones Cardiovasculares) CBM Centre of Molecular Biology (Centro de Biología Molecular) Madrid, Spain Madrid, Spain CNIO Spanish National Cancer Centre CBRI CBR Institute for Biomedical Research, Harvard Medical School (Centro Nacional de Investigaciones Oncológicas) Boston, USA Madrid, Spain CBS Structural Biology Centre (Centre de Biochimie Structurale) CNR-IBC Italian National Research Centre, Institute of Cell Biology Montpelier, France (Consiglio Nazionale delle Ricerche, Istituto di Biologia Cellulare) CEA Atomic Energy Commission Rome, Italy (Commissariat à l'Energie Atomique) CNRS French National Centre for Scientifi c Research Grenoble, France (Centre national de la recherche scientifi que) CeMM Research Center for Molecular Medicine of France the Austrian Academy of Sciences COSI Cavalieri Ottolenghi Scientifi c Institute of Neurobiology (Forschungszentrum für Molekulare Medizin) Torino, Italy Vienna, Austria CRG Center for Genomic Regulation (Centre de Regulacio Genomica) CGMC Center for Molecular and Cellular Genetics Barcelona, Spain (Centre de Génétique Moléculaire et Cellulaire) Lyon, France

➔ 138 organisations and acronyms

CSAT Centre for Research in Biomedicine and Organ and ESF European Science Foundation Tissue Transplants (Centro Superior en Alta Tecnología Científi ca Strasbourg, France para la Investigación en Biomedicina y Trasplantes de Tejidos y ETH Swiss Federal Institute of Technology Zurich Órganos de la Comunidad Valenciana) Valencia, Spain (Eidgenössische Technische Hochschule Zürich) CSCHAH Canadian Science Centre for Human and Animal Health Switzerland Winnipeg, Canada EU TMR European Union's Research Training Networks – Training and CSHL Cold Spring Harbor Laboratory, Mobility of Researchers (Europe-wide) USA FEBS Federation of European Biochemical Societies CSIC Spanish National Research Council Europe-wide (Consejo Superior de Investigaciones Científi cas) FHCRC Fred Hutchinson Cancer Research Center Spain Seattle, USA CSIRO Commonwealth Scientifi c and Industrial Research Organisation FIRC Italian Cancer Research Foundation Urrbrae, Australia (Fondazione Italiana per la Ricerca sul Cancro) DBJC Joliot-Curie Biology Department, CEA Saclay Milan, Italy Gif-sur-Yvette, France FMI Friedrich Miescher Institute for Biomedical Research DKBW Department of Clinical Biological Research, University of Basel Basel, Switzerland (Department Klinisch-Biologische Wissenschaften, Universität Forfás National Policy Advisory Board of the Basel), Switzerland Department of Enterprise, Trade and Employment DKFZ German Cancer Research Center Dublin, Ireland (Deutsches Krebsforschungszentrum) FRM French Medical Research Foundation Heidelberg, Germany (Fondation pour la Recherche Médicale) DRFZ German Rheumatology Research Institute Paris, France (Deutsches Rheuma-Forschungszentrum) GRICES Offi ce for International Relations in Science and Berlin, Germany Higher Education (Gabinete de Relações Internacionais da DUMC Duke University Medical Centre Ciência e do Ensino Superior) Durham, USA Lisbon, Portugal ELSF European Life Sciences Forum GSF National Research Center for Environment and Health Europe-wide (Forschungszentrum für Umwelt und Gesundheit) ELSO European Life Scientist Organization Neuherberg, Germany Europe-wide HFSP Human Frontier Science Program EMBL European Molecular Biology Laboratory Strasbourg, France Europe-wide HHMI Howard Hughes Medical Institute EMC Erasmus Medical Centre, Erasmus University Rotterdam Chevy Chase, USA (Universitair Medisch Centrum, Erasmus Universiteit Rotterdam) HINARI Health InterNetwork Access to Research Initiative, The Netherlands World Health Organization (WHO) ENS Ecole Normale Supérieure Geneva, Switzerland Paris, France HKI Hans Knöll Institute, Leibniz Institute for Natural Product EPFL-LCB Swiss Federal Institute of Technology Lausanne Research and Infection Biology (Hans-Knöll-Institut, Laboratory of Cell Biophysics Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie) (École Polytechnique Fédérale de Lausanne) Jena, Germany Switzerland

➔ 139 organisations and acronyms

HMS Harvard Medical School, IIMCB International Institute of Molecular and Cell Biology Boston, USA Warsaw, Poland IBB-PAS Institute of Biochemistry and Biophysics IISc Indian Institute of Science Polish Academy of Sciences Bangalore, India Warsaw, Poland IMBB-FORTH Institute of Molecular Biology & Biotechnology IBCP Institute for the Biology and Chemistry of Proteins Heraklion, Greece (Institut de Biologie et de Chimie des Protéines) IMBV Department of Molecular Biosciences, University of Oslo Lyon, France (Institutt for molekylær biovitenskap, Universitetet i Oslo) IBDM Developmental Biology Institute of Marseille Norway (Institut de Biologie du développement de Marseille) IMCR Institute of Molecular Cancer Research, University of Zurich France Switzerland IBMC Institute for Molecular and Cell Biology IMIM Medical Research Institute (Institut de Biologie Moléculaire et Cellulaire) (Institut Municipal d'Investigació Médica) Strasbourg, France Barcelona, Spain IBMP Institute of Plant Molecular Biology IMP Research Institute of Molecular Pathology (Institut de Biologie Moléculaire des Plantes) (Forschungsinstitut für Molekulare Pathologie) Strasbourg, France Vienna, Austria IBPC Institute of Biology and Physical Chemistry IMU Innsbruck Medical University (Institut de Biologie Physico-Chimique) (Medizinische Universität Innsbruck) Paris, France Austria IBS Jean-Pierre Ebel Structural Biology Institute INA Alicante Institute of Neuroscience (Institut de Biologie Structurale Jean-Pierre Ebel) (Instituto de Neurociencias de Alicante) Grenoble, France Spain IChBFM Institute of Chemical Biology and Fundamental Medicine INIM Institute of Clinical Neuroimmunology Novosibirsk, Russia (Institut für Klinische Neuroimmunologie) ICSM Imperial College School of Medicine Munich, Germany London, UK INRA French National Institute for Agricultural Research ICT Institute of Chemical Technology Prague (Institut National de la Recherche Agronomique) (Vysoká Škola Chemicko-Technologická v Praze) France Czech Republic INSERM French National Institute for Health and Medical Research IFOM FIRC Institute of Molecular Oncology (Institut national de la santé et de la recherche médicale) (Istituto FIRC di oncologia molecolare) France Milan, Italy INTA National Institute for Agricultural Technology IGBMC Institute of Genetics and Molecular and Cellular Biology Castelar, Argentina (Institut de Génétique et de Biologie Moléculaire et Cellulaire) IPB Leibniz Institute of Plant Biochemistry Illkirch, France (Leibniz Institut für Pfl anzenbiochemie) IGH Institute of Human Genetics Halle, Germany (Institut de Génétique Humaine), Montpelier, France IPBO Plant Biotechnology Institute for Developing Countries, IGMM Institute of Molecular Genetics of Montpelier Gent University (Instituut voor Plantenbiotechnologie voor (Institut de Génétique Moléculaire de Montpelier) Ontwikkelingslanden) France Belgium

➔ 140 organisations and acronyms

IPK Institute of Plant Genetics and Crop Plant Research MATFORSK Norwegian Food Research Institution (Institut für Pfl anzengenetik und Kulturpfl anzenforschung) Aas, Norway Gatersleben, Germany MBC Max Bergmann Center of Biomaterials, Technical University IPMC Institute of Molecular and Cellular Pharmacology of Dresden (Max-Bergmann-Zentrum für Biomaterialien, (Institut de Pharmacologie Moléculaire et Cellulaire) Technische Universität Dresden) Valbonnes – Sophia Antipolis, France Germany IRBM P. Angeletti Molecular Biology Research Institute MBK Agricultural Biotechnology Center (A Kutatóközpontot) P. Angeletti (Istituto di Ricerca di Biologia Molecolare P. Angeletti) Gödöllö, Hungary Rome, Italy MDC Max Delbrück Centre for Molecular Medicine IRIBHM Institute of Interdisciplinary Research in (Max-Delbrück-Centrum für Molekulare Medizin) Human and Molecular Biology Berlin, Germany Brussels, Belgium MEC Ministry of Education and Science IRP-HSG Institute for Legal Studies and Legal Practice, (Ministerio de Educación y Ciencia) University of St. Gallen (Institut für Rechtswissenschaft und Madrid, Spain Rechtspraxis, Universität St. Gallen) MHH Hannover Medical School (Medizinische Hochschule Hannover) St. Gallen, Switzerland Germany ISC Experimental Institute for Cereal Research MIT Massachusetts Institute of Technology (Istituto Sperimentale per la Cerealicoltura) Cambridge, USA Foggia, Italy MPI Max Planck Institute (Max-Planck-Institut) ISREC Swiss Institute for Experimental Cancer Research Germany (Institut Suisse de Recherche Expérimentale sur le Cancer) MPI-CBG Max Planck Institute of Molecular Cell Biology and Genetics Epalinges, Switzerland (Max-Planck-Institut für molekulare Zellbiologie und Genetik) IUB International University of Bremen Dresden, Germany (International Universität Bremen) MRC Medical Research Council, United Kingdom Germany MRC-LMB Medical Research Council Laboratory of Molecular Biology KNAW Royal Netherlands Academy of Arts and Sciences Cambridge, UK (Koninklijke Nederlandse Akademie van Wetenschappen) MSKCC Memorial Sloan-Kettering Cancer Center Amsterdam, The Netherlands New York, USA LBPA Biotechnology and Applied Genetic Pharamacology Laboratory MSSM Mount Sinai School of Medicine (Laboratoire de Biotechnologies et Pharmacologie Génétique New York, USA Appliquée) MTA Hungarian Academy of Sciences Cachan, France (Magyar Tudományos Akadémia) LEBS Laboratory of Structural Enzymology and Biochemistry Budapest, Hungary (Laboratoire d'Enzymologie et Biochimie Structurales) NCMLS Nijmegen Centre for Molecular Life Sciences Gif-sur-Yvette, France The Netherlands LICR Ludwig Institute for Cancer Research NCSU North Carolina State University Worldwide Raleigh, USA LMU Ludwig Maximilian University (Ludwig-Maximilians-Universität) NIAID National Institute of Allergy and Infectious Diseases Munich, Germany Bethesda, USA LSHTM London School of Hygiene & Tropical Medicine NIBGE National Institute for Biotechnology and Genetic Engineering University of London, UK Faisalabad, Pakistan

➔ 141 organisations and acronyms

NIEB Nencki Institute of Experimental Biology UPMC Pierre and Marie Curie University Warsaw, Poland (Université Pierre et Marie Curie) NIH National Institutes of Health Paris, France Bethesda, USA USTC University of Science and Technology of China NIMR National Institute for Medical Research Hefei, China London, United Kingdom VIB Flanders Interuniversity Institute for Biotechnology NKI Netherlands Cancer Institute (Nederlands Kanker Instituut) (Vlaams Interuniversitair Instituut voor Biotechnologie) Amsterdam, The Netherlands Belgium NPHI National Public Health Institute WEHI The Walter and Eliza Hall Institute of Medical Research (Kansanterveyslaitos Folkshälsoinstitutet) Melbourne, Australia Helsinki, Finland WIBR Whitehead Institute for Biomedical Research NYU New York University Cambridge, USA USA WTCCB Wellcome Trust Centre for Cell Biology, University of Edinburgh OCEAC-IRD Coordinating organisation for the fi ght against endemics in UK Central Africa (Organisation de Coordination pour la lutte contre WTSI Wellcome Trust Sanger Institute les Endémies en Afrique Centrale) Hinxton, UK Yaoundé, Cameroon ZMBE Center for Molecular Biology of Infl ammation OCMS Oxford Centre for Molecular Sciences (Zentrum für Molekularbiologie der Entzündung) UK Münster, Germany OMRF Oklahoma Medical Research Foundation Oklahoma City, USA PICR Paterson Institute for Cancer Research Manchester, UK PRI Plant Research International Wageningen, The Netherlands SFI Science Foundation Ireland SICMMB Sars International Centre for Marine Molecular Biology Bergen, Norway SILS Swammerdam Institute for Life Sciences University of Amsterdam The Netherlands TIGEM Telethon Institute of Genetics and Medicine Naples, Italy TSRI The Scripps Research Institute La Jolla, USA UAM Autonomous University of Madrid (Universidad Autónoma de Madrid) Madrid, Spain ULB Free University of Brussels (Université Libre de Bruxelles) Belgium

➔ 142 European Molecular concept, co-ordination, editing Biology Organization Christine Blaumueller, Lindsay Johnson, Meyerhofstr. 1 Anne Seller D-69117 Heidelberg Germany production: co-ordination, phone +49 6221 8891 0 layout, graphics, cover fax +49 6221 8891 200 Uta Mackensen [email protected] www.embo.org photos European Molecular Maj Britt Hansen, Udo Ringeisen, Marietta Schupp Biology Conference (EMBL Photolab) Meyerhofstr. 1 D-69117 Heidelberg print Germany MERA DRUCK Druckerei GmbH phone +49 6221 8891 111 Sandhausen, Germany fax +49 6221 8891 210 [email protected] www.embo.org/embc