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The European Peptide Society Newsletter THE EUROPEAN PEPTIDE SOCIETY NEWSLETTER ISSUE NUMBER 53, FEBRUARY 2016 A Message from the Chairpersons of the 34th EPS Peptide Science in Finland 23rd Polish Peptide Symposium 5th Austrian Peptide Symposium 2015 Robert Schwyzer (1920 – 2015) EPS Founder Medal presentation Published online by the Journal of Peptide Science The Official Journal of the European Peptide Society A Message from the Chairpersons of the 34th European Peptide Symposium Cover photo: The new Paulinum of the University of Leipzig, the Symposium TH European Peptide Germany – Leipzig Venue of the forthcoming 34th EPS 34 Symposium 04 September 2016 to TH International Peptide 09 September 2016 8 Symposium IN THIS ISSUE www.34eps-2016.org A Message from the Chairpersons of the 34th EPS . .2 Peptide Science in Finland . .3 Dear Friends, Partners and Colleagues, 23rd Polish Peptide Symposium . .6 5th Austrian Peptide It is our great pleasure to welcome you at the 34th European Peptide Symposium 2015 . .9 Symposium and the 8th International Peptide Symposium, that will take Robert Schwyzer (1920–2015) 12 EPS Founder Medal place from September 4th to 9th in Leipzig, Germany. presentation . .16 We expect participants from all over the world working in all aspects of Society Officers . .17 Calendar . .18 this prosperous field of peptide science – ● from chemical synthesis to biology NEWSLETTER EDITOR Professor Krzysztof Rolka ● from Academia to Industry! Faculty of Chemistry University of Gdansk ● from experienced, well-known experts to motivated PL-80308 Gdansk, Poland Tel: + 48 58 5235088 new-comers in the field Fax: + 48 58 5235012 E-mail : [email protected] The European and International Peptide Symposium 2016 provides an excellent platform to exchange ideas on latest approaches and SOCIETY NEWSLETTER discoveries in all aspects of peptide science. Join us! Come to Leipzig, This Newsletter is published in cooperation with the Journal of Peptide to this beautiful city in the heart of Germany, with a long tradition in Science twice a year and can be obtained as a free PDF download from the science, culture and trade. European Peptide Society website at: www.eurpepsoc.com Welcome to Leipzig – don’t miss this great event! Journal of Peptide Science, the official journal of the European Peptide Society EPS, is an online journal published by Annette G. Beck-Sickinger John Wiley & Sons Ltd on the Wiley Online Library as 12 issues each year. Ulf Diederichsen Information on and access to the journal Chairs of Symposium can be obtained at: wileyonlinelibrary.com/journal/jpepsci 2 CONFERENCE REPORT Peptide Science in Finland Finnish Peptide Society (FIPS) – symposia 2015 report innish Peptide Society (FIPS, Mart Saarma, Jean Martinez, Mohamed sium. Neurodegerative diseases are http://www.biobio.org/peptide/ Marahiel, Marcel Jaspars, Tambet increasing in Western world and their Findex.html) was established 1997 Teesalu, Jouni Jokela, Pirjo Laakkonen treatment is a great challenge. Novel to promote peptide science in Finland. and Anja Sandström. The main themes of approaches for treatment of these FIPS is a subdivision of BioBio society, the symposium were emerging targets in diseases are needed and were presented which promotes biological research in central nervous system (CNS) diseases, by several speakers. Professor Alan P Finland, and of course member of EPS. macrocycles in drug space, green Kozikowski from University of Illinois at Although FIPS is a small society, con- chemistry and green medicinal chemistry, Chicago talked about HDAC6 inhibitors in sisting of about 40 members, its biannual peptides as drugs and natural peptides. CNS (and cancer). Our “old grand man” symposia have recently attracted inter- Overall joint theme was related to drugs professor Jean Martinez (Montpellier national audience and much more in middle space, i.e., to drug molecules University) spoke about novel peptides participants than just the members of the which are bigger than conventional small that target brain angiotensin converting society. Previous symposium “Emerging molecules and smaller than proteins. enzyme and stimulate dopamine release targets and molecules in middle space”, Such molecules include peptides and in CNS. These peptides, identified using was jointly organized by FIPS, the Finnish peptidomimetics. Traditional screening an impressive combination of bioinfor- Synthetic Chemistry Society and the campaigns for small molecules have not matics, chemical, biochemical and analy- Medicinal Chemistry Committee of the been very successful, which has caused tical approaches, may be useful for Finnish Pharmaceutical Society (FinMed shift towards bigger molecules and novel treatment of neurodegenerative diseases, Chem) at Helsinki on August 24–27, approaches. Professor Eckhard Ottow like Alzheimer’s and Parkinson’s diseases. 2015. The symposium attracted over 100 from German Chemical Society, GDCh, Professor Mart Saarma (University of participants of whom a fourth were from highlighted this and other trends and Helsinki), one of the leading researchers abroad. The audience consisted mainly challenges in drug discovery in his talk. of nerve growth factors, introduced novel academic and industry scientists, and He also stressed the importance of growth factors and peptides for the students. medicinal chemistry in drug discovery treatment of Parkinson’s disease. These One of the aims of the joint symposium and development. growth factors have been very promising was to strengthen the dialogue between First day of the symposium was started in preclinical animal tests. peptide science, synthetic chemistry and with synthetic chemistry and posters. Third day was dedicated to medicinal medicinal chemistry. This was already Along with medicinal chemistry and green chemistry and macrocycles. While the last started two years earlier when FIPS chemistry themes the second day day’s topic was “Peptide drugs and organized first joint meeting with FinMed included also peptide related topics in a natural peptides”. During these days both Chem. Joint symposium also allowed us session of “CNS targets and neuro- natural and synthetic peptides were to invite as many as 20 prominent peptides”, a theme which was also con- addressed. Many natural peptides, plenary speakers, of whom FIPS invited tinued on the fourth day of the sympo- including those produced by certain 3 Peptide Science in Finland bacteria and algae, and other marine lasso-peptides, which are stable peptides produced by cyanobacteria and how organisms, have properties which makes produced by bacteria and have unique these can be produced by enzymatic those suitable for drug development. properties which make them interesting methods in E. coli. Dr Jouni Jokela Professor Mohamed Marahiel from candidates for drug development. Pro- (University of Helsinki) continued this Philipps University Marburg gave an fessor Marcel Jaspars (University of topic by describing several peptides pro- interesting and stimulating talk about Aberdeen) introduced us to the peptides duced by cyanobacteria. Professor John “Emerging targets and molecules in middle space” symposium awardees and some of the plenary speakers. Plenary speakers from left, Mart Saarma, Pirjo Laakkonen, Anja Sandström (back row), John Sigurd Svendsen, Eckhard Ottow and Jean Martinez. Awardees on front row, from left, Kadri Toome, Anu Humisto, Mira Kuusisto, Tuomas Tolvanen and Annakaisa Heikinheimo (Arjan van Adrichem is not in the picture). 4 Sigurd Svendsen (University of Tromsø) of molecules that retain the binding the tradition of the joint symposium is addressed antimicrobial peptides. properties and biological activity of the planned to be continued, the next While phage-display derived peptides peptides, but are structurally different symposium to be held at 2017. were briefly touched on several talks the from the natural peptides. The chairmen of the symposium and new developments and applications of The above captures only a small part of organizing committees were Professor this technique were presented by Pro- the excellent talks in the symposium. In Kristiina Wähälä (FinMedChem), Profes- fessor Tambet Teesalu (University of addition to 20 plenary talks, 15 other oral sor Ari Koskinen (Finnish Synthetic Tartu, Estonia) who talked about tumor communications were presented. These Chemistry Society) and Dr. Hannu homing peptides, their discovery and included several excellent talks by Koistinen (FIPS). applications, and Dr Pirjo Laakkonen students. In poster session 32 posters FIPS was also one of the organizer of (University of Helsinki) who presented were presented. Best three posters and the 1st Finnish Symposium on Biological peptide-based brain tumor targeting. Both three oral presentations by students were Mass Spectrometry, which was held on speakers addressed the use of homing awarded. Prizes for best oral presen- April 14 – 16, 2015 at Tampere, Finland. peptides for tumor imaging and targeted tations were given to Tuomas Tolvanen The symposium was organized by the delivery of drugs. Such peptides have a (University of Helsinki), Mira Kuusisto Finnish Proteomics Society (FinnProt), the great potential to diminish side effects of (University of Jyväskylä) and Arjan van Finnish Mass Spectrometry Society the current treatments. Adrichem (University of Helsinki), and (FMSS) and FIPS. The plenary speakers The second last talk of the symposium, poster prizes to Annakaisa Heikinheimo were Nevena Zivanovic (University of before professor Mart Saarma’s lecture (Aalto
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