Dani Rodrik Recalibrates Economics Dani Rodrik Recalibrates Economics
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Cannabinoids and Endocannabinoid System Changes in Intestinal Inflammation and Colorectal Cancer
cancers Review Cannabinoids and Endocannabinoid System Changes in Intestinal Inflammation and Colorectal Cancer Viktoriia Cherkasova, Olga Kovalchuk * and Igor Kovalchuk * Department of Biological Sciences, University of Lethbridge, Lethbridge, AB T1K 7X8, Canada; [email protected] * Correspondence: [email protected] (O.K.); [email protected] (I.K.) Simple Summary: In recent years, multiple preclinical studies have shown that changes in endo- cannabinoid system signaling may have various effects on intestinal inflammation and colorectal cancer. However, not all tumors can respond to cannabinoid therapy in the same manner. Given that colorectal cancer is a heterogeneous disease with different genomic landscapes, experiments with cannabinoids should involve different molecular subtypes, emerging mutations, and various stages of the disease. We hope that this review can help researchers form a comprehensive understanding of cannabinoid interactions in colorectal cancer and intestinal bowel diseases. We believe that selecting a particular experimental model based on the disease’s genetic landscape is a crucial step in the drug discovery, which eventually may tremendously benefit patient’s treatment outcomes and bring us one step closer to individualized medicine. Abstract: Despite the multiple preventive measures and treatment options, colorectal cancer holds a significant place in the world’s disease and mortality rates. The development of novel therapy is in Citation: Cherkasova, V.; Kovalchuk, critical need, and based on recent experimental data, cannabinoids could become excellent candidates. O.; Kovalchuk, I. Cannabinoids and This review covered known experimental studies regarding the effects of cannabinoids on intestinal Endocannabinoid System Changes in inflammation and colorectal cancer. In our opinion, because colorectal cancer is a heterogeneous Intestinal Inflammation and disease with different genomic landscapes, the choice of cannabinoids for tumor prevention and Colorectal Cancer. -
CZECH MYCOLOGY Formerly Česká Mykologie Published Quarterly by the Czech Scientific Society for Mycology
r 7|— I VOLUME 48 L ^ Z - t U M M A Y 1 9 9 5 My c o l o g y l CZECH SCIENTIFIC SOCIETY FOR MYCOLOGY PRAHA JSAYCU N l . o Clov J < M ^/\YCU ISSN 0009-0476 n§ ! r % . O o v J < Vol. 48, No. 1, May 1995 CZECH MYCOLOGY formerly Česká mykologie published quarterly by the Czech Scientific Society for Mycology EDITORIAL BOARD Editor-in-Chief ZDENĚK POUZAR (Praha) Managing editor ; JAROSLAV KLÁN (Praha) VLADIMÍR ANTONÍN (Brno) JIŘÍ KUNERT (Olomouc) OLGA FASSATIOVÁ (Praha) LUDMILA MARVANOVÁ (Brno) ROSTISLAV FELLNER (Praha) PETR PIKÁLEK (Praha) JOSEF HERINK (Mnichovo Hradiště) MIRKO SVRČEK (Praha) Czech Mycology is an international scientific journal publishing papers in all aspects of mycology. Publication in the journal is open to members of the Czech Scientific Society for Mycology and non-members. Contributions to: Czech Mycology, National Museum, Department of Mycology, Václavské nám. 68, 115 79 Praha 1, Czech Republic. Phone: 02/24230485 SUBSCRIPTION. Annual subscription is Kč 250,- (including postage). The annual sub scription for abroad is US $80,- (including postage). The annual membership fee of the Czech Scientific Society for Mycology (Kč 160,- or US $ 60,- for foreigners) includes the journal without any other additional payment. For subscriptions, address changes, pay ment and further information please contact The Czech Scientific Society for Mycology, P.O.Box 106, 11121 Praha 1, Czech Republic. Copyright © The Czech Scientific Society for Mycology, Prague, 1995 : No. 4 of the vol. 47 of Czech Mycology appeared in February 16, 1995 CZECH MYCOLOGY Publication of the Czech Scientific Society for Mycology Volume 48 May 1995 Number 1 Articles published in this number of Czech Mycology were presented at 7th International Congress of Mycology Division (IUMS - 94) in Prague, July 3 - 8, 1994. -
AAHE Bibliography on Higher Education
DOCUMENT RESUME ED 038 907 HE 001 440 1UTHOR Kelsey, Roger R. TTTLE A.A.H.E. Bibliography on Higher Education. TNsTTITTToN American Association for Iligher Education, Washington, D.C. PUB DATE 1 liar 70 NOTE 57p.; Prepared for the 25th National Conferenceof the American Association for Higher Education, Chicago, Ill., March 1-4, 1970 AVAILABLE ?EOM Roger P. Kelsey, 700 Ludlow St., Takoma Park, Md. 20012 ($1.00) EDRS PRICE EDRS Price MF-$0.25 HC-$2.95 DESCRIDTORS Admission (School), Adult Education, *Bibliographies, Curriculum, Educational Administration, Educational Facilities, Educational Finance, *Educational History, Faculty, Graduate Study, *Higher Education, Junior Colleges,Learning, Libraries, *Students, Teaching Methods, *ULdergraduate Study ABSTRACT This bibliography lists 1473 books pertainingto or about higher education exhibited at the AmericanAssociation on Higher Education's 25th National Conference inChicago. The document is comprised of 16 categorical sections withan introductory annotation at the beginning of each. Publicationentries on respective subjects of higher educationcover:(1) history, philosophy, sociology, and general development--369;(2) organization and administration--112;(3) finance, budget, and business administration--57;(4) faculty personnel- -L=8; (5) directories--27; (6) admission and registration -r32; (7) student personnel--184; (8) teaching methods and media--107; (9)learning and psychological factors--72;(10) graduate curricula--40;(11) adult and university extension curricula--29; (12) undergraduate -
Iii. Administración Local
BOCM BOLETÍN OFICIAL DE LA COMUNIDAD DE MADRID Pág. 468 LUNES 21 DE MARZO DE 2011 B.O.C.M. Núm. 67 III. ADMINISTRACIÓN LOCAL AYUNTAMIENTO DE 17 MADRID RÉGIMEN ECONÓMICO Agencia Tributaria Madrid Subdirección General de Recaudación En los expedientes que se tramitan en esta Subdirección General de Recaudación con- forme al procedimiento de apremio, se ha intentado la notificación cuya clave se indica en la columna “TN”, sin que haya podido practicarse por causas no imputables a esta Administra- ción. Al amparo de lo dispuesto en el artículo 112 de la Ley 58/2003, de 17 de diciembre, Ge- neral Tributaria (“Boletín Oficial del Estado” número 302, de 18 de diciembre), por el presen- te anuncio se emplaza a los interesados que se consignan en el anexo adjunto, a fin de que comparezcan ante el Órgano y Oficina Municipal que se especifica en el mismo, con el obje- to de serles entregada la respectiva notificación. A tal efecto, se les señala que deberán comparecer en cualquiera de las Oficinas de Atención Integral al Contribuyente, dentro del plazo de los quince días naturales al de la pu- blicación del presente anuncio en el BOLETÍN OFICIAL DE LA COMUNIDAD DE MADRID, de lunes a jueves, entre las nueve y las diecisiete horas, y los viernes y el mes de agosto, entre las nueve y las catorce horas. Quedan advertidos de que, transcurrido dicho plazo sin que tuviere lugar su compare- cencia, se entenderá producida la notificación a todos los efectos legales desde el día si- guiente al del vencimiento del plazo señalado. -
Six Canonical Projects by Rem Koolhaas
5 Six Canonical Projects by Rem Koolhaas has been part of the international avant-garde since the nineteen-seventies and has been named the Pritzker Rem Koolhaas Architecture Prize for the year 2000. This book, which builds on six canonical projects, traces the discursive practice analyse behind the design methods used by Koolhaas and his office + OMA. It uncovers recurring key themes—such as wall, void, tur montage, trajectory, infrastructure, and shape—that have tek structured this design discourse over the span of Koolhaas’s Essays on the History of Ideas oeuvre. The book moves beyond the six core pieces, as well: It explores how these identified thematic design principles archi manifest in other works by Koolhaas as both practical re- Ingrid Böck applications and further elaborations. In addition to Koolhaas’s individual genius, these textual and material layers are accounted for shaping the very context of his work’s relevance. By comparing the design principles with relevant concepts from the architectural Zeitgeist in which OMA has operated, the study moves beyond its specific subject—Rem Koolhaas—and provides novel insight into the broader history of architectural ideas. Ingrid Böck is a researcher at the Institute of Architectural Theory, Art History and Cultural Studies at the Graz Ingrid Böck University of Technology, Austria. “Despite the prominence and notoriety of Rem Koolhaas … there is not a single piece of scholarly writing coming close to the … length, to the intensity, or to the methodological rigor found in the manuscript -
Marc Corrales Berjano
Text in context: Chromatin effects in gene regulation Marc Corrales Berjano TESI DOCTORAL UPF / 2017 DIRECTOR DE LA TESI Dr. Guillaume Filion DEPARTAMENT Gene Regulation, Stem cells and Cancer Genome architecture Center for Genomic Regulation (CRG) ii a mi familia, iii Aknowledgements I want to thank the members of the doctoral board, present and substitutes, for accepting to analize my work and defend my thesis. I also want to thank my thesis commitee Dr. Miguel Beato, Dr. Jordi Garcia-Ojalvo and Dr. Tanya Vavouri for guidance and valuable scientific imput whenever I needed it along these years. I want to thank my mentor Dr. Guillaume Filion, not only for giving me the opportunity to carry this work in a wonderful environement, but for teaching me. No matter the tigh schedule he has allowed me to sit by his side (literally) reviewing a script at the computer, calculating the probaility of plasmid recircularization or deriving a statistical formula at the white board but also helping me to prepare and electroporate a bacterial library in what seemed a contraction of space-time. I want to thank the community of the CRG, always ready to discuss science and life in the corridors, the data seminars, symposiums, the beer sessions or following a mail asking for advice or materials. People at the administration helped enormously to navigate the tortuous bureaucratic world, maximizing the time one can dedicate toscience. ¡Dónde estaría yo sin tu puerta siempre abierta, Imma, madre en funciones de todo phD student! I want to thank the CRG for funding my phD and for constituting what I envisage as the perfect environment to learn to be a scientist. -
2019 Annual Report
BECKMAN CENTER 279 Campus Drive West Stanford, CA 94305 650.723.8423 Stanford University | Beckman Center 2019 Annual Report Annual 2019 | Beckman Center University Stanford beckman.stanford.edu 2019 ANNUAL REPORT ARNOLD AND MABEL BECKMAN CENTER FOR MOLECULAR AND GENETIC MEDICINE 30 Years of Innovation, Discovery, and Leadership in the Life Sciences CREDITS: Cover Design: Neil Murphy, Ghostdog Design Graphic Design: Jack Lem, AlphaGraphics Mountain View Photography: Justin Lewis Beckman Center Director Photo: Christine Baker, Lotus Pod Designs MESSAGE FROM THE DIRECTOR Dear Friends and Trustees, It has been 30 years since the Beckman Center for Molecular and Genetic Medicine at Stanford University School of Medicine opened its doors in 1989. The number of translational scientific discoveries and technological innovations derived from the center’s research labs over the course of the past three decades has been remarkable. Equally remarkable have been the number of scientific awards and honors, including Nobel prizes, received by Beckman faculty and the number of young scientists mentored by Beckman faculty who have gone on to prominent positions in academia, bio-technology and related fields. This year we include several featured articles on these accomplishments. In the field of translational medicine, these discoveries range from the causes of skin, bladder and other cancers, to the identification of human stem cells, from the design of new antifungals and antibiotics to the molecular underpinnings of autism, and from opioids for pain -
INDEX to 1915-1919 Obituaries in the Canton Repository
INDEX To 1915-1919 Obituaries in the Canton Repository Published by the Stark County District Library of Canton, Ohio 2005 Index to 1915-1919 Obituaries in the Canton Repository The following is an alphabetical listing, by the deceased’s surname, of obituaries that appeared in the Canton, Ohio newspaper, The Repository. It was compiled by the library staff during the course of the year in the hope that it would be a useful tool to genealogy, as well as other researchers. To use this index, simply locate the name of the person whose obituary you wish to find. The entries will appear as follows: Miller William A. (Estella M.) Mrs. 1924 Jan. 13 30 The first column is the name of the deceased. The second gives the date on which the item appeared. And the third tells the page number containing the obituary. You may find one name with multiple listings showing different dates and locations in the paper. This indicates consecutive listings for that individual. I encourage you to view each for additional information. Index to 1915-1919 Obituaries in the Canton Repository Surname Given Name Maiden Title Year Mth Day Pg ? Mary 1918 Apr. 18 15 Aaron Benjamin 1918 Nov. 27 2 Abbott Lawrence C. 1919 Mar. 14 24 Abels infant 1919 July 16 6 Abherve Minnie Jacobs Mrs. 1918 Dec. 13 33 Abrams Leo 1917 Apr. 24 2 Abt Leo 1918 Apr. 27 1 Abvrezis Macone 1917 Sept. 17 2 Acker L. E. 1918 Jan. 13 26 Acker Leonard E. 1918 Jan. 12 5 Acker Sarah Mrs. -
Certified Contractor List.Xlsx
Certified Contractors That Have Filed A State License With The City of Sanibel Listing Updated: 02/17/2021 License Category License Year Sanibel License State License Company Name License Holder Company Phone Air Conditioning 2119260 CAC1817193 99 Air and Appliances LLC Kovalchuk, Ilya 239-601-0267 Air Conditioning 2119813 CAC1819907 A Colonial Roofing Co Rawlings, Joshua Patrick 239-770-5005 Air Conditioning 2122364 CAC1820193 A/C Medic 911 LLC Boots, David 239-283-7911 Air Conditioning 2106217 CAC057171 Absolute Best Inc Best, Bradley M 239-482-2225 Air Conditioning 2118599 CAC1813368 AC Joe Heating & Cooling LLC Strickland, Daryl F 239-540-5940 Air Conditioning 2116497 CAC1814145 AC Keepers Inc Keep, Brian Todd 239-332-0330 Air Conditioning 2119592 CAC057968 AC Pros Johnson, Wesley S 239-218-4051 Air Conditioning 2118965 CAC1816379 Acman LLC Corredor, Diego A 239-225-8994 Air Conditioning 2112887 CAC1813574 Action Cooling + Heating, Inc. Whitacre, Thurman L II 239-768-7005 Air Conditioning 2121370 CAC1819956 Affordable Air + Heating Dalton, Kevin 239-772-0053 Air Conditioning 2116001 CAC1813217 Air Advantage Heating & Cooling Inc Bramhall, Scott C 239-433-4635 Air Conditioning 2119494 CAC1813568 Air Affects Cooling & Heating Yackle, John C 239-980-3474 Air Conditioning 2116869 CAC1816885 Air Experts Diedrich, Ryan M 941-758-5000 Air Conditioning 2122503 CAC1819749 Air Force 1 Whitty, Kevin F 239-368-6464 Air Conditioning 2119143 CAC1818661 Air Innovations of Florida Collins, Bryan J 239-543-0023 Air Conditioning 2115184 CAC1813198 -
British Family Names
cs 25o/ £22, Cornrll IBniwwitg |fta*g BOUGHT WITH THE INCOME FROM THE SAGE ENDOWMENT FUND THE GIFT OF Hcnrti W~ Sage 1891 A.+.xas.Q7- B^llll^_ DATE DUE ,•-? AUG 1 5 1944 !Hak 1 3 1^46 Dec? '47T Jan 5' 48 ft e Univeral, CS2501 .B23 " v Llb«"y Brit mii!Sm?nS,£& ori8'" and m 3 1924 olin 029 805 771 The original of this book is in the Cornell University Library. There are no known copyright restrictions in the United States on the use of the text. http://www.archive.org/details/cu31924029805771 BRITISH FAMILY NAMES. : BRITISH FAMILY NAMES ftbetr ©riain ano fIDeaning, Lists of Scandinavian, Frisian, Anglo-Saxon, and Norman Names. HENRY BARBER, M.D. (Clerk), "*• AUTHOR OF : ' FURNESS AND CARTMEL NOTES,' THE CISTERCIAN ABBEY OF MAULBRONN,' ( SOME QUEER NAMES,' ' THE SHRINE OF ST. BONIFACE AT FULDA,' 'POPULAR AMUSEMENTS IN GERMANY,' ETC. ' "What's in a name ? —Romeo and yuliet. ' I believe now, there is some secret power and virtue in a name.' Burton's Anatomy ofMelancholy. LONDON ELLIOT STOCK, 62, PATERNOSTER ROW, E.C. 1894. 4136 CONTENTS. Preface - vii Books Consulted - ix Introduction i British Surnames - 3 nicknames 7 clan or tribal names 8 place-names - ii official names 12 trade names 12 christian names 1 foreign names 1 foundling names 1 Lists of Ancient Patronymics : old norse personal names 1 frisian personal and family names 3 names of persons entered in domesday book as HOLDING LANDS temp. KING ED. CONFR. 37 names of tenants in chief in domesday book 5 names of under-tenants of lands at the time of the domesday survey 56 Norman Names 66 Alphabetical List of British Surnames 78 Appendix 233 PREFACE. -
Boston Tech Hub Faculty Working Group Annual Report: 2019-2020
BOSTON TECH HUB FACULTY WORKING GROUP Annual Report 2019–2020 Technology and Public Purpose Project Belfer Center for Science and International Affairs Harvard Kennedy School 79 JFK Street Cambridge, MA 02138 www.belfercenter.org/TAPP Harvard John A. Paulson School of Engineering and Applied Sciences 29 Oxford St., Cambridge, MA 02138 www.seas.harvard.edu Statements and views expressed in this report are solely those of the authors and do not imply endorsement by Harvard University, Harvard Kennedy School, Harvard Paulson School, or the Belfer Center for Science and International Affairs. Design and Layout by Andrew Facini Copyright 2020, President and Fellows of Harvard College Printed in the United States of America BOSTON TECH HUB FACULTY WORKING GROUP Annual Report 2019-2020 Table of Contents Foreword ........................................................................................................................1 FWG Members and Guests .........................................................................................5 Introduction ................................................................................................................ 13 Summary ..................................................................................................................... 14 FWG Session Briefs: Fall 2019 ................................................................................19 FWG Session Briefs: Spring 2020 ..........................................................................31 Carol Rose, Executive Director -
2017 Program in New England Studies Schedule Monday, June 19 – Saturday, June 24
2017 Program in New England Studies Schedule Monday, June 19 – Saturday, June 24 Schedule subject to change Monday, June 19: Seventeenth-Century Massachusetts Bay Tuesday, June 20: Eighteenth-Century Piscataqua Wednesday, June 21: Eighteenth Century Thursday, June 22: Nineteenth Century Friday, June 23: Victorian Era Saturday, June 24: Colonial Revival Monday, June 19: Seventeenth-Century Massachusetts Bay 9:30 a.m. Breakfast and Registration at Otis House in Boston 10:00 a.m. Welcome and Orientation 10:15 a.m. How Colonial New England Became Britain’s Pottery Barn Cary Carson, Vice President, Research Division (retired), Colonial Williamsburg Foundation 11:30 a.m. Seventeenth-Century Architecture Claire Dempsey, Associate Professor of American and New England Studies, Boston University 12:45 p.m. Lunch 1:15 p.m. Depart for Saugus, Mass. 2:00 p.m. Tours of Boardman House (c. 1687), Saugus, Mass., and Gedney House (1665), Salem, Mass. Cary Carson and Ben Haavik, Team Leader, Property Care, Historic New England 5:30 p.m. Return to Boston Tuesday, June 20: Eighteenth-Century Piscataqua 7:45 a.m. Depart Otis House for Portsmouth, N.H. 2017 Program in New England Studies Schedule Monday, June 19 – Saturday, June 24 9:00 a.m. Eighteenth-Century Architecture James L. Garvin, State Architectural Historian (retired), New Hampshire Division of Historical Resources 10:30 a.m. Tour of Moffatt-Ladd House (1763) Barbara McLean Ward, Ph.D., Director and Curator, Moffatt-Ladd House and Garden and James L. Garvin Noon Lunch at Moffatt-Ladd House 1:00 p.m. New England House and Home Jane C.