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Handbook of Cell Signaling Second Edition

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Handbook of Cell Signaling Second Edition Handbook of Cell Signaling Second Edition Volume 2 Editors-in-Chief Ralph A. Bradshaw Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California Edward A. Dennis Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California ->*-*-"NCi '-Si- AMSTERDAM • BOSTON • HEIDELBERG • LONDON • NEW YORK • OXFORD • PARIS SAN DIEGO • SAN FRANCISCO • SINGAPORE • SYDNEY • TOKYO ELSEVIER Academic Press is an imprint of Elscvier Contents VOLUME 2 64. The Negative Regulation of JAK/STAT signaling 467 Contributors xxi James M. Murphy, Gillian M. Tannahill, Preface to the Second Edition xliii Douglas J. Hilton and Christopher J. Greenhalgh Preface to the First Edition xlv 65. Protein Kinase Inhibitors 481 Part II Alexander Levitzki Transmission: Effectors and Cytosolic Events 385 66. Integrin Signaling: Cell Migration, Tony Hunter Proliferation, and Survival 491 J. Thomas Parsons, Jill K. Slack-Davis, Robert W. Section A - Protein Phosphorylation 391 Tilghman, Marcin Iwanicki and Karen H. Martin Tony Pawson 67. Downstream Signaling Pathways: 56. Eukaryotic Kinomes: Genomics and Modular Interactions 501 Evolution of Protein Kinases 393 Bruce J. Mayer Gerard Manning and Tony Hunter 68. Non-Receptor Tyrosine Kinases in T Cell 57. Modular Protein Interaction Domains in Antigen Receptor Function 507 Cellular Communication 399 Susan E. Levin and Arthur Weiss Tony Pawson and Piers Nash 69. Receptor Tyrosine Kinase Signaling and 58. Structures of Serine/Threonine and Ubiquitination 517 Tyrosine Kinases 413 Daniela Hoeller and Ivan Dikic Stevan R. Hubbard 59. Protein Tyrosine Kinase Receptor 70. TGFp Signal Transduction 521 Signaling Overview 419 Cristoforo Silvestri, Rohit Bose, Liliana Attisano and Carl-Henrik Heldin Jeffrey L. Wrana 60. Signaling by the Platelet-Derived 71. Mitogen-Activated Protein Kinases 533 Growth Factor Receptor Family 427 Eric Ho and Jim Woodgett Lars Ronnstrand 72. Recognition of Phospho-Serine/ 61. The Epidermal Growth Factor Receptor Threonine Phosphorylated Proteins by Family 435 Phospho-Serine/Threonine-Binding Wolfgang J. Kostler and Yosef Yarden Domains 539 62. Mechanisms and Functions of Eph Stephen J. Smerdon and Michael B. Yaffe Receptor Signaling 443 Martin Lackmann 73. AMP-Activated Protein Kinase 551 D. Grahame Hardie 63. Cytokine Receptor Signaling 451 Mojib Javadi Javed, Terri D. Richmond and 74. Principles of Kinase Regulation 559 Dwayne L Barber Bostjan Kobe and Bruce E. Kemp Contents 75. Calcium/Calmodulin-Dependent 86. The Structure and Topology of Protein Protein Kinase II 565 Serine/Threonine Phosphatases 677 Mary B. Kennedy David Barford 76. Glycogen Synthase Kinase 3 569 87. Naturally Occurring Inhibitors of Protein Philip Cohen and Sheelagh Frame Serine/Threonine Phosphatases 683 Carol MacKintosh and Julie Diplexcito 77. The PIKK Family of Protein Kinases 575 88. Protein Phosphatase 1 Binding Graeme C. M. Smith and Stephen P. Jackson Proteins 689 Anna A. DePaoli-Roach 78. Histidine Kinases in Two-Component Signaling Pathways 581 89. Protein Serine/Threonine Phosphatase Alia O. Kaserer and Ann H. West Inhibitors and Human Disease 699 79. The EF2K/MHCK/TRPM7 Family of Shirish Shenolikar and Matthew H. Brush Atypical Protein Kinases 587 90. Calcineurin 705 Shari L. Wiseman, Fan-Yan Wei, and Claude B. Klee and Seun-Ah Yang Angus C. Nairn 80. The Leucine-Rich Repeat Receptor 91. Protein Serine/Threonine-Phosphatase Protein Kinases of Arabidopsis 2C (PP2C) 711 thaliana - a Paradigm for Plant LRR His'ashi Tatebe and Kazuhiro Shiozaki Receptors 601 John C. Walker and Kevin A. Lease 92. Approaches to the Identification of Protein Tyrosine Phosphatase 81. Engineering Protein Kinases with Substrates 717 Specificity for Unnatural Nucleotides Anton M. Bennett and Tony Tiganis and Inhibitors 609 Chao Zhang and Kevan M. Shokat 93. Inhibitors of Protein Tyrosine Phosphatases 727 82. Clinical Applications of Kinase Zhong-Yin Zhang Inhibitors in Solid Tumors 615 William Pao and Nicolas Girard 94. Regulating Receptor PTP Activity 737 Aurnab Ghose and David Van Vactor 83. Ubiquitin-mediated Regulation of Protein Kinases in NFK,B 95. CD45 743 Signaling 633 Michelle L. Hermiston, Vikas Gupta and Ming Xu and Zhijian J. Chen Arthur Weiss 84. Global Analysis of Phosphoregulatory 96. Cell-Cycle Functions and Regulation of Networks 645 Cdc14 Phosphatases 749 Janine Mok and Michael Snyder Harry Charbonneau Section B - Protein Dephosphorylation 657 97. MAP Kinase Phosphatases 755 Nick Tonks Stephen M. Keyse 85. Phosphatase Families 98. SH2 Domain-Containing Protein- Dephosphorylating Serine and Tyrosine Phosphatases 771 Threonine Residues in Proteins 659 Benjamin G. Neel, Gordon Chan, and Patricia T.W. Cohen Salim Dhanji Contents 99. Insulin Receptor PTP: PTP1B 811 110. Phospholipase C 887 Sofi G. Julien and Michel L. Tremblay Hong-Jun Liao and Graham Carpenter 100. STYX/Dead Phosphatases 817 111. Cyclic ADP-ribose and NAADP 893 Matthew J. Wishart Antony Galione and Grant C. Churchill 112. Voltage-Gated Calcium Channels 897 101. Zebrafish and Phosphatase William A. Catterall Function 827 Jeroen den Hertog and Mark van Eekelen 113. Store-Operated Calcium Channels 911 James W. Putney 102. Eyes Absent Protein Tyrosine 2+ Phosphatases: A New Eukaryotic 114. Arachidonic Acid-Regulated Ca Branch of the Haloacid Dehalogenase Channel 915 Superfamily 835 Trevor J. Shuttleworth Carolyn N. Wrobel and llaria Rebay 115. IP3 Receptors 921 103. PHLPP: PH Domain Leucine-Rich Colin W. Taylor and Zhao Ding Repeat Protein Phosphatase 843 Alexandra C. Newton 116. Ryanodine Receptors 927 David H. MacLennan and S. R. Wayne Chen 104. PTEN 849 117. Intracellular Calcium Signaling 937 Lloyd C. Trotman Dagmar Harzheim, H. Llewelyn Roderick and Martin D. Bootman 105. PTP Oxidation 855 Ming-Fo Hsu, Yi-Wei Lou, Yi-Yun Chen and 118. Calcium Pumps 943 Tzu-Ching Meng Ernesto Carafoli, Laura Fedrizzi, Teuta Domi, Francesca Di Leva and 106. Chronophin and Slingshot Cofilin Marisa Brini Phosphatases in Cytoskeletal Regulation 863 119. Sodium/Calcium Exchange 949 Celine DerMardirossian, Timothy Y. Huang and Mordecai P. Blaustein Gary M. Bokoch 120. Ca2+ Buffers 955 107. Large Scale Structural Analysis of Beat Schwaller Protein Tyrosine Phosphatases 871 AlastairJ. Barr and Stefan Knapp 121. Mitochondria as Organizers of the Cellular Ca2+ Signaling Network 963 108. Protein Phosphatases and Circadian Gydrgy Szabadkai and Michael R. Duchen Clocks 877 122. EF-Hand Proteins and Calcium Yanshan Fang and Amita Sehgal Sensing: The Neuronal Calcium Sensor Proteins 973 Section C - Calcium Signal Transduction 883 tee P. Haynes and Robert D. Burgoyne Martin D. Bootman 123. Calmodulin-Mediated Signaling 979 109. Calcium Signalling; Messengers, Anthony R. Means Transport Pathways, Sensors, and Physiological Outcomes 885 124. The Family of S100 Cell Signaling Martin D. Bootman and Proteins 983 H. Llewelyn Roderick Claus W. Heizmann and Gunter Fritz Contents 125. Annexins and Calcium Signaling 995 137. PX Domains 1103 Stephen E. Moss Christian D. Ellson and Michael B. Yaffe 126. Calpain 999 138. FYVE Domains in Membrane Trafficking Alan Wells and Ludovic Leloup and Cell Signaling 1111 127. Calcium Signaling in Smooth Christopher Stefan, Anjon Audhya and Scott D. Emr Muscle 1009 Susan Wray 139. Protein Kinase C: Relaying Signals 128. Calcium Signaling in Cardiac from Lipid Hydrolysis to Protein Muscle 1027 Phosphorylation 1123 K.M. Dibb, A.W. Traffordand D.A. Eisner Alexandra C. Newton Section D - Lipid-Derived Second 140. Modulation of Monomeric G Proteins Messengers 1031 by Phosphoinositides 1131 Lewis Cantley Sonja Vermeren, Len Stephens and Phillip T. Hawkins 129. Historical Overview: Protein Kinase C, Phorbol Ester and Lipid 141. Phosphoinositides and Actin Mediators 1033 Cytoskeletal Rearrangement 1141 Yasutomi Nishizuka and Ushio Kikkawa Paul A. Janmey, Robert Bucki and Helen L. Yin 130. Type I Phosphatidylinositol 4-Phosphate 5-Kinases (PHP 142. Phosphatidylinositol Transfer 5-kinases) 1037 Proteins 1151 Shamshad Cockcroft K.A. Hinchliffe and R.F. Irvine 131. Type II PIP4-kinases 1043 143. Inositol Pentakisphosphate: A Signal Lucia Rameh Transduction Hub 1159 Stephen B. Shears 132. Phosphoinositide 3-Kinases 1049 David A. Fruman 144. Phospholipase D 1167 Wenjuan Su and Michael A. Frohman 133. PTEN/MTM Phosphatidylinositol Phosphatases 1061 145. Diacylglycerol Kinases 1177 Knut Martin Torgersen, Soo-A Kim and Matthew K. Topham and Steve M. Prescott Jack E. Dixon 146. Sphingosine-1-Phosphate Receptors: 134. The Src Homology 2 Containing An Update 1183 Inositol 5' Phosphatases 1065 Michael Maceyka and Sarah Spiegel Frann Antignano, Jens Ruschmann, Melisa Hamilton, Victor Ho, Vivian Lam, Etsushi Kuroda, Laura M. Sly and Gerald Krystal 147. Lysophosphatidic Acid and Sphingosine-1 -Phosphate Activation of 135. Structural Principles of Lipid Second G-Protein-Coupled Receptors 1191 Messenger Recognition 1085 Tetsuji Mutoh and Jerold Chun Roger L. Williams 148. The Role of Ceramide in Cell 136. Pleckstrin Homology (PH) Regulation 1201 Domains 1093 Leah J. Siskind, Thomas D. Mullen and Mark A. Lemmon Lina M. Obeid Contents IX 149. Role of Phospholipase A2 Forms in 160. Signaling and the Immunological ArachidonicAcid Mobilization and Synapse 1283 Eicosanoid Generation 1213 Emanuele Giurisato and Andrey S. Shaw Jesus Balsinde and Edward A. Dennis 161. The Ubiquitin-Proteasome 150. Prostaglandin Mediators 1219 System 1293 Emer M. Smyth and Garret A. FitzGerald Mark Hochstrasser 151. Leukotriene Mediators
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