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iProstate Cancer Foundation Annual Report 04 1250 Fourth Street Santa Monica, California 90401 Tel 310.570.4700 Fax 310.570.4701 www.prostatecancerfoundation.org Donations Please mail your check to: Prostate Cancer Foundation 1250 Fourth Street Santa Monica, California 90401 To make an online contribution, please visit our Web site: prostatecancerfoundation.org. To make a credit card donation, call 800.757.CURE. Memorial or Tribute Gifts Honor the memory of a loved one or celebrate the accomplish- ment of a friend or family PCF member by helping others. 2004 WAS A REMARKABLE YEAR. Make a memorial or tribute gift and the PCF will send an Fortune featured the PCF in its November cover story acknowledgment card to the entitled “Beating Cancer,” and named the PCF as its offi cial family of the honoree. philanthropy to celebrate its 75th anniversary. Other Gift Suggestions For the fi rst time ever, the U.S. Food and Drug Adminis- tration approved a drug (Taxotere) that extends life for men Assets or property including with advanced prostate cancer. appreciated stock and real estate. The PCF expanded its donor base by 35%. Bequest—Include a gift to the PCF in your will. And, signifi cant progress was made in demonstrating the link between nutrition, especially antioxidants, and Name the PCF as the primary prostate cancer. or contingent benefi ciary on a life insurance policy. Editors: Sarah Evans, Jessica Niebauer Contributor: Jon Greer Special Thanks: Aaron Ciechanover, M.D., D.Sc., Steve Burd, Don Coffey, Ph.D. , Rosey Grier, Beth Kobliner Shaw, Nelson Peltz, Marvin R. Shanken, Wade F.B. Thompson, Joe Torre Photography: Michael D’Ambrosia Design: KBDA, Los Angeles More information: www.prostatecancerfoundation.org Fortune magazine noted the PCF and Mike Milken have… “…managed to raise the profi le of prostate cancer signifi cantly, increase funding dramatically to fi ght the dis- ease, spur innovative research, attract new people to the fi eld, get myriad drugs into clinical trials, and dare we say, speed up science.” November 29, 2004 2Prostate Cancer Foundation DEAR FRIENDS Last spring, Fortune magazine arrived on our desks with a dispiriting cover story titled “Why We’re Losing the War on Cancer.” The article argued that the “cancer establishment” was wasting time and resources while millions of cancer patients were left waiting for new treatments and a cure for their disease. While we respected Fortune’s took our advice, and the We have funded more than analysis, it simply didn’t resulting cover story ran in 1,200 prostate cancer research square with what we were November 2004 under the projects at more than 100 experiencing at the Prostate headline “Beating Cancer.” institutions worldwide. We Cancer Foundation. Here, have successfully advocated Harnessing Our Power we saw the best and brightest for massive increases in federal researchers making real strides At the PCF, we are doing funding for prostate cancer in understanding this disease everything in our power to research, leveraging your con- and testing new treatments. beat cancer. Starting a little tributions many times over. We were identifying visionary more than a decade ago, we Moreover, we have contin- leaders working relentlessly to turned the “cancer establish- uously worked to clear the remove roadblocks to the de- ment” on its ear, transforming barriers to successful prostate velopment of better treatments prostate cancer research from cancer research. We have and potential cures. And, we a backwater into one of the established novel alliances were researching treatments most important areas of cancer among research institutions and lifestyle changes available research. We have raised more and bridged the gap between to patients right now, helping than $230 million from major clinicians in the various medi- many live longer. donors, corporations, leading cal disciplines, providing them brands and individuals to We felt so strongly, in fact, that with valuable insight into the fund prostate cancer research, we suggested to Fortune that research process and gaining quickly establishing the PCF they do a follow-up story on their help in speeding prostate as the world’s leading phil- the success of the PCF. They anthropic source of support for prostate cancer research. 3 cancer treatments through through the clinical pipeline the development process. toward regulatory approval. We have opened doors to key In 1993, men without prostate government offi cials, provid- cancer didn’t have their pros- ing them with information tate specifi c antigen (PSA) and support to both rally levels routinely checked governmental resources and because the test wasn’t even reduce bureaucratic barriers. approved as a preventive screening method. Today, Achieving Results tens of millions of men have In 2004, we issued the fi rst- their PSA levels checked, ever Report to the Nation on allowing physicians to catch Today, breakthroughs in Prostate Cancer, in which 24 prostate cancer at very early prostate cancer research seem prostate cancer thought leaders stages while also increasing to happen almost daily, with outlined the state of the art in treatment options. new reports streaming out the diagnosis, treatment and Today, breakthroughs in about advances in drug devel- prevention of prostate cancer prostate cancer research seem opment, treatment options, and laid out a clear agenda to happen almost daily, with diagnostic capabilities and for future progress. new reports streaming out new lifestyle choices. The results? We are fi ghting about advances in drug devel- cancer in meaningful ways. opment, treatment options, In 2004, an estimated 30,000 diagnostic capabilities and men died of prostate cancer, new lifestyle choices. A recent a 26% decrease in prostate pinnacle of scientifi c achieve- cancer deaths from 1993, ment was reached with the when the PCF was founded. awarding of the 2004 Nobel In 1993, there were fi ve Prize in Chemistry to Aaron approved drugs for treating Ciechanover, M.D., D.Sc., a prostate cancer. Today there recipient of multiple PCF are 13 approved drugs, with research grants, to support many more making their way his award-winning research into the proteasome, which regulates the abundance of key proteins involved in cell survival. 4 Prostate Cancer Foundation A Team Effort are likely to die from prostate This year, we urge you cancer in 2005. Moreover, to act and help the Prostate Indeed, it’s a very exciting with the aging of the baby Cancer Foundation continue time to be working on your boomer generation, we await to beat cancer. behalf to fi nd better treat- a wave of new prostate cancer ments and an ultimate cure Sincerely, cases, upwards of 300,000 a for recurrent prostate cancer. year by 2015, and a death rate We have been joined in our spiraling up to 50,000 men Michael Milken work by an impressive lineup per year. Founder and Chairman of supporters, including Major League Baseball, Safeway, These sobering statistics eBay, AriZona Beverages, guide us in everything we do. Yahoo!, News Corp., Hugo If we are to continue to beat Boss and many more. We prostate cancer, we will have have persuaded the two most to marshal far more resources populous states in the U.S., and persuade many more New York and California, to people to join our cause. include a tax-form check-off That’s why we continue to to support prostate cancer. need your help. We’re doing Leslie D. Michelson We have generated a wave of Vice Chairman and everything we possibly can, publicity about our cause with Chief Executive Offi cer around the clock, to beat the help of NBC’s Today show; cancer—raising funds, sup- our “Act. Like a Man.” public porting researchers, breaking service advertising campaign, down barriers, creating produced by TBWA\Chiat\ alliances—but to do more, Day; and, yes, a cover story we must have your help. in Fortune magazine. You Must Act Yet we stay focused on our goal, and for a very good With your generous support, reason: In 2005, an estimated we can fund more of the 232,000 men will be diag- many worthy research grant nosed with prostate cancer. requests that arrive at our Despite all our achievements offi ces every day. With your to date, another 30,000 men help, we will continue to clear the scientifi c and bureaucratic hurdles that impede progress and cause needless suffering. We can’t do it alone. It’s as simple as that. To beat prostate cancer once and for all, we must leverage the talents and resources of thousands of people and institutions around the world. Collaboration, cooperation and teamwork have been hallmarks of the PCF from the start, and they remain important components of the PCF’s ongoing strategy. Our sup- porters include the people featured in this report—men with prostate cancer, loved ones and others who simply care. Join us. 6Prostate Cancer Foundation PROSTATE CANCER Cancer of the prostate is the most common non-skin cancer STATUS UPDATE in America. One in six American men will be diagnosed with prostate cancer. A man is 33% more likely to get prostate cancer than a woman is to get breast cancer. Prostate cancer is a scourge—it attacks millions of men as they age. Last year, 232,000 men received a prostate cancer diagnosis, and the disease took the lives of some 30,000 men, including the famous—Law & Order’s Jerry Orbach, Citigroup’s Walter Wriston, legendary guitarist Johnny Ramone—as well as everyday loved ones—someone’s father, son, brother, friend. The prostate is no bigger than a walnut, yet it plays a key role in the male reproductive system. Located in a hard-to-reach place between the penis and the bladder, it is unusually susceptible to cancer.
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