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March 02 Nucleus N/L Finalsaltu DED UN 18 O 98 F yyyy N yyyy Y O T R E I T H C E N O yyyy A E S S S L T A E A C R C I yyyyN S M S E E H C C T N IO A March 2002 Vol. LXXX, No. 7 yyyyC N • AMERI Monthly Meeting Richards Medal to Stephen J. Lippard Meeting Report What Is Different about Fluorocarbons? by David M. Lemal Summer Scholar Report Toward a Small-Molecule Activated Protein Splicing System Book Review Having Faith, an ecologist’s journey to motherhood by Sandra Steingraber 2 The Nucleus March 2002 The Northeastern Section of the American Monthly Meeting _______________________________________5 Chemical Society, Inc. Office: Marilou Cashman, 23 Cottage St., Richards Medal to Stephen J. Lippard ( M.I.T.): Three Avenues in Bioinorganic Natick, MA 01760. 1-800-872-2054 Chemistry: Cisplatin, Methane Monooxygenase, and Metalloneurochemistry (Voice or FAX) or 508-653-6329. e-mail: [email protected] Any Section business may be conducted Who Was Theodore William Richards?______________________6 via the business office above. NESACS Homepage: Pictures on pp. 24-25 http://www.NESACS.org Frank R. Gorga, Webmaster Meeting Report 8 Washington, D.C. ACS Hotline: ________________________________________ 1-800-227-5558 January 2002 Meeting Address:What Is Different About Fluorocarbons? Officers 2002 By David M. Lemal Chair: Morton Z. Hoffman Chemistry Department, Boston University ACS Short Course_____________________________________13 Boston, MA 02215-2507; 617-353-2494 [email protected] Interpretation of Mass Spectra, May 2 and 3, 2002 Chair-Elect: John L. Neumeyer Section Business _____________________________________14 Harvard Medical School/McLean Hospital 115 Mill St., Belmont, MA 02478; Candidates for 2003, Board of Directors Meeting of December 6, 2001 617-855-3388 [email protected] Immediate Past Chair: Summer Research Report 16 Timothy B. Frigo _______________________________ Advanced Magnetics, Inc. Toward a Small-Molecule Activated Protein Splicing System, 61 Mooney St., Cambridge, MA 02138 617-497-2070x3007 [email protected] by Ravi V. Shah, Joshua M. Finkelstein, and Gregory L. Verdine (Harvard) Secretary: Michael Singer Book Review _________________________________________22 Sigma RBI 3 Strathmore Rd. Having Faith, an Ecologist’s Journey to Motherhood, by Sandra Steingraber; Natick, MA 01760-2447 reviewed by Dennis Sardella 508-651-8151x291 [email protected] Treasurer: Puzzle Column _______________________________________23 James Piper Simmons College, 300 The Fenway Solution to the February Puzzle: p. 21 Boston, MA 02115, 617-521-2722 [email protected] Cover: Stephen J. Lippard in the Saddle Auditor: Anthony Rosner Archivist: Deadlines: May 2002 issue: March 14, 2002 Myron Simon 20 Somerset Rd. Summer Issue: June 28, 2002 (National Meeting Issue) Newton, MA 02465; 617-332-5273 [email protected] Trustees: Michael E. Strem, Joseph A. Lima, Esther A.H. Hopkins Councilors: Alternate Councilors: Term Ends 12/31/2002 Term Ends 12/31/2002 The Nucleus is distributed to the members of the Northeastern Section of the American Chemical Mary T. Burgess Michael J. Dube Society, to the secretaries of the Local Sections, and to editors of all local A.C.S. Section publications. Michaeline F. Chen Jean Fuller-Stanley Forms close for advertising on the 1st of the month of the preceding issue. Text must be received by the Doris I. Lewis Patrick M. Gordon editor six weeks before the date of issue. Julia H. Miwa John L. Neumeyer Editor: Arno Heyn, 21 Alexander Rd., Newton, MA 02461, Term Ends 12/31/2003 Term Ends 12/31/2003 Catherine E. Costello Wallace J. Gleekman Tel: 617-969-5712, FAX: 617-527-2032; e-mail: [email protected] William Klemperer Arno H.A. Heyn Associate Editor: Myron S. Simon, 20 Somerset Rd., W. Newton, MA 02465, Tel: 617-332-5273 Dorothy J. Phillips Howard R. Mayne Board of Publications: Patrick M. Gordon (Chair), Frank R. Gorga, Marietta H. Schwartz, E. Joseph Barbara G. Wood Alfred Viola Billo (Consultant) Term Ends 12/31/2004 Term Ends 12/31/2004 Business Manager: Karen Piper, 19 Mill Rd., Harvard, MA 01451, Thomas R. Gilbert Timothy B. Frigo Tel: 978-456-8622 Patricia H. Hamm Morton Z. Hoffman Michael J. Hearn Truman S. Light Advertising Manager: Vincent J. Gale, P.O. Box 1150, Marshfield, MA 02050, Arlene W. Light Donald O. Rickter Tel: 781-837-0424; FAX: 781-837-8792 Contributing Editors: Mukund Chorghade, Patricia Hamm, Features; Edward Atkinson, History of All Chairs of standing Chemistry; Maryann Solstad, Health; Dennis Sardella, Book Reviews; Marietta H. Committees, the editor Schwartz, Software Reviews; E. Joseph Billo, Puzzles. of THE NUCLEUS, and the Trustees of Section Calendar Coordinator: Donald O. Rickter, e-mail: [email protected] Funds are members of the Proofreaders: E. Joseph Billo, Donald O. Rickter, M.S. Simon Board of Directors. Any Webpage: Webmaster: Frank R. Gorga, [email protected] Councilor of the American Chemical Society Asst. Webmasters:Terry Brush, [email protected] residing within the section area is an ex officio Kurt Heinselman, [email protected] member of the Board of Directors. Copyright 2002, Northeastern Section of the American Chemical Society, Inc. The Nucleus March 2002 3 Biography Corporate Patrons Alfa Aesar, a Johnson Matthey Com- Stephen J. Lippard is series “Progress in pany the Arthur Amos Inorganic Chem- Hoechst Marion Roussel Co. Noyes Professor of istry” from Volume Pharm-Eco Laboratories, Inc. Chemistry and Head 11 to 40, w as an Physical Sciences, Inc. of the Chemistry Associate Editor of Polaroid Corporation Department at the the journal Inorganic Strem Chemicals, Inc. Massachusetts Insti- Chemistry, is now an Corporate Sponsors tute of Technology. Associate Editor of Aerodyne Research, Inc. He was born in Pitts- the Journal of the AstraZeneca R&D burgh, Pennsylvania American Chemical Borregaard Synthesis, Inc. and educated in the Society, was a Bristol-Myers Squibb Pittsburgh public Founding member of Cambridge Isotope Labs schools. He studied at the Editorial Advi- Consulting Resources Corporation Haverford College sory Board for Dike, Bronstein, Roberts & (B.A., magna cum Chemical Research Cushman, LLP laude, 1962) and the Stephen J. Lippard (Photo by Bachrach) in Toxicology, and Houghton Chemical Corp. Massachusetts Insti- serves or has served JEOL, USA, Inc. tute of Technology (Ph.D, 1965). After on the editorial boards of Accounts of MassTrace, Inc. a postdoctoral year at MIT during Chemical Research, Anticancer Drug New England Biolabs 1965-66 he joined the f aculty of Design, Bioorganic & Medicinal Organix, Inc. Columbia University as an Assistant Chemistry, Bioorganic & Medicinal Pfizer, Inc. Professor of Chemistry, being pro- Chemistry Letters, ChemBioChem, Research Biochemicals Int’l moted to Associate Professor with Chemical and Engineering News, Zymark Corporation tenure in 1969 and to Professor in Chemical Research and Technology, 1972. In January of 1983 he moved to Chemistry & Biology, Inorganic Chem- MIT. He has taken sabbatical leaves at istry, Inorganic Chemistry Concepts, the University of Göteborg in Sweden, Inorganica Chimica Acta, Journal of New the MRC Laboratory of Molecular Biological Inorganic Chemistry, Jour- Biology in Cambridge, England, the nal of Inorganic Biochemistry, and Anorganisch-Chemisches Institut der Topics in Biological Inorganic Chem- Members Technischen Universität München, istry. He is the author or co-author of Includes members relocated to the Garching, Federal Republic of Ger- over 550 publications in the fields of Northeastern Section many, and the University of California, inorganic and coordination chemistry, Invitation to attend a Section San Diego. organometallic chemistry, and biologi- meeting Professor Lippard has held fellow- cal chemistry. You are cordially invited to attend one ships from the Woodrow Wilson Foun- He has co-authored a book with of our upcoming Section meetings as dation, the National Science Jeremy Berg entitled “Principles of guest of the Section at the Social hour Foundation, The Alfred P. Sloan Foun- Bioinorganic Chemistry.” He holds and Dinner Meeting. dation, The Camille and Henry Drey- several US. and foreign patents. He has fus Foundation, the Guggenheim chaired several symposia at American Please call Marilou Cashman at Foundation, and the John E. Fogarty Chemical Society national meetings, 800-872-2054, 508-653-6329, or: International Center. was Alternate Councilor for the Divi- [email protected] by noon of the He is a member of the American sion of Inorganic Chemistry, was first Thursday of the month, to accept this invitation, letting her know that Chemical Society, The Royal Chairman of the Bioinorganic Subdivi- N Society of Chemistry, The American sion, and Chairman of the Inorganic you are a new member. Crystallographic Association, The Bio- Division. He has given over 50 named physical Society. He was elected to lectureships at universities both in this ration, Johnson Matthey Co., Procept, Phi Beta Kappa (junior year), Sigma country and abroad, served as a panel Smith Kline & Beckman, Suntech and Xi, and the American Society of Bio- member of the Medicinal Chemistry John Wiley & Sons, Inc. He is cur- logical Chemists, and a Fellow of Study Section B and BMT Study Sec- rently Chairman of the Scientific Advi- the American Association for the tion of the National Institutes of sory Board of N AXCOR He was Advancement of Science. Health, and has been a consultant for Chairman of the 1985 Gordon He was editor of the well-known Engelhard Corporation, Exxon Corpo- continued on
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