Vol. 2, 611, March 1996 Clinical Cancer Research 611

Annual Meeting fee. (If additional funding is received, some The AACR’s Annual Meeting is one of the larg- AACR travel support may be available for junior fac- est and most important annual gatherings of sci- The American Association for Cancer Re- ulty.) entists engaged in cancer research worldwide. search (AACR) was founded in 1907 to bring The Workshop Organizing Committee is The next Annual Meeting will take place in together active investigators of the cancer chaired by Drs. Daniel D. Von Hoff(for AACR) Washington, D. C., from April 20-24, l996. The problem for the presentation and discussion of and Charles A. Coltman, Jr. (for ASCO), both of the Cancer Therapy and Research Center in Chairperson ofthe Annual Meeting is Lorraine J. new findings and to foster advances in cancer San Antonio, Texas. They will invite and se- Gudas of the Cornell University Medical Col- research. Today the Association has more than 10,000 members working in all of the subdis- lect a distinguished faculty that will deliver lege. Dr. Gudas and her Program Committee ciplines of cancer research in the United over 20 hours of lectures on a variety of topics have invited outstanding scientists in the field to States, Canada, and more than 50 other coun- in the field and direct four 2-hour small group organize plenary sessions, symposia, methods tries. Information on AACR programs and ac- discussion sessions in which 25-30 partici- workshops, controversy sessions, and meet-the- tivities can be obtained from pants will obtain practical training in subjects expert sunrise sessions. The Committee has just American Association for that are essential to the success of clinical completed the scheduling of proffered papers in Cancer Research trials. In addition, all participants will be re- minisymposia, poster discussion sessions, and sponsible the preparation and submission Public Ledger Building for poster sessions. The deadline for abstract sub- 150 South Independence Mall West of a concept sheet for an actual clinical trial missions was December 1, 1995. Suite 816 protocol. Faculty will review and provide de- Philadelphia, PA 19106.3483 tailed critiques of these concept sheets. ASCO Phone: (215) 440-9300 will certify this workshop for Category 1 cred- its toward the AMA Physicians Recognition Fax: (215) 440-9313 Workshop on Molecular Biology in Award. The AACR welcomes applications for mem- Clinical Oncology Information and application forms will be bership from the readership. Scientists en- The AACR will sponsor an intensive, one- mailed to AACR and ASCO members in gaged in all areas of cancer research are eligi- March. Nonmembers should request brochures week summer workshop on molecular biology ble for membership. There are three categories from the AACR office. The deadline for re- designed for clinical oncologists in training of membership: active membership, open to ceipt of applications will be April 25, 1996. and in their early academic careers. The work- cancer researchers working in the Americas; shop will take place at the Given Institute in corresponding membership, to those working AACR Special Conferences in Aspen, Colorado, from June 28-July 4, 1996. outside the Americas; and associate member- Cancer Research Recent advances in molecular biology are be- ship, to graduate and medical students, post- A number of meetings are now being orga- coming more and more relevant to the diag- doctoral fellows, and physicians-in-training. nized in the AACR’s new series of smaller nosis, therapy, and management of cancer Further information on the qualifications for scientific meetings. Following are the topics, patients. The workshop will give clinical on- each category as well as the benefits of mem- dates, locations, and program committees for cologists the opportunity to interact closely in bership can be found on the application forms some of these meetings. When full details of at the back of this issue. an informal setting with experts in the field of each meeting are available, AACR members molecular biology, learn their language and will be the first to receive complete brochures laboratory techniques, better understand rele- and application forms for participation in these vant literature, and communicate more effec- Workshop on Methods in Clinical important conferences. Nonmembers may re- tively with their basic science colleagues. Cancer Research ceive this information by sending their names Stephen H. Friend of the Fred Hutchinson This August the AACR and the American So- and addresses to Meetings Mailing List, Ameri- Cancer Research Center, L. Michael Glod#{233}of ciety of Clinical Oncology (ASCO) will intro- can Association for Cancer Research, Public the University of Colorado School of Mcdi- duce a new, 6-day summer workshop on din- Ledger Building, 150 South Independence Mall cine, and Jennifer A. Pietenpol of the Vander- ical research methods designed for both West, Suite 816, Philadelphia, PA 19106-3483. bilt University School of Medicine will serve oncobogists in training and senior investiga- Telephone: (215) 440-9300. FAX: (215) 440- as chairpersons of the workshop and will invite tors. The workshop will take place at the Inn at 9313. E-Mail: [email protected]. a distinguished faculty to direct five 2#{189}-hour Prospector Square in Park City, Utah, from June 8-12, 1996 laboratory sessions and deliver 20 hours of August 17-23, 1996. The overall goal of the Inducible Genomic Responses lectures. Generous support from the National workshop will be to educate clinical scientists Chairpersons: Cancer Institute will provide funding for the in methods for clinical research and to encour- WILLIAM T. BECK, Memphis, TN registration fees and hotel accommodations of age better clinical trial design so that new JOHN A. HICKMAN, Birmingham, England 65 physicians in training and oncology fel- cancer treatments can be introduced more rap- RICHARD I. MORIMOTO, Evanston, IL lows. Ten senior clinical oncologists will also idly into general medical practice. Major sup- Skamania Lodge, Stevenson (Columbia River be able to attend the workshop upon payment port for this program has already been ob- Gorge), WA of a registration fee. The University of Cob- tamed from Bristol-Myers Squibb and Hoechst October 2-6, 1996 rado School of Medicine certifies this work- Marion Roussel Amgen, and a grant proposal Novel Approaches in Blood and Marrow shop for Category 1 credits toward the AMA has been submitted to the National Cancer Transplantation Physicians Recognition Award. Institute. Funds will be available to offset the Second Annual Meeting of the American Information and application forms were registration fees and housing and subsistence Society for Blood and Marrow Transplantation mailed to AACR members in January. Non- expenses for 75 clinical trainees to attend the Chairpersons: members should request brochures from the workshop. In addition, 25 clinical investigators 0. MICHAEL COLVIN, Durham, NC AACR office. Applications are due in the at the level ofjunior faculty will be accepted to BRUCE R. BLAZAR, Minneapolis, MN AACR office by March 25, 1996. the workshop upon payment of a registration Hotel Del Coronado, San Diego, CA Clinical Cancer Research i

Instructions for Authors

Scope have been approved by the investigator’s Institutional Review Board. Clinical Cancer Research, a journal of the American Associa- tion for Cancer Research, publishes original articles describing clinical research on the cellular and molecular characterization, Review Process prevention, diagnosis, and therapy of human cancer. Its focus is The review process, expedited by fax transmission and over- on innovative clinical research and translational research which night mail service, is conducted as rapidly as possible. Each bridges the laboratory and the clinic. Clinical Cancer Research submitted manuscript is reviewed by at least two experts in the is especially interested in clinical trials evaluating new treat- field of investigation. If the authors are invited to submit a ments for cancer; research on molecular abnormalities that pre- revised manuscript for an expedited further review, the revised dict incidence, response to therapy, and outcome; and laboratory version must be submitted within three months. studies of new drugs and biological agents that will lead to clinical trials in patients. Specific areas of interest include clinical and translational Manuscript Submission research in: molecular and chemotherapy; drug Send manuscripts to John Mendelsohn, M.D., Editor-in-Chief, sensitivity and resistance; tumor and immunother- Clinical Cancer Research, at Department of Medicine, Memo- apy; radiobiology and radiation oncology; solid tumor oncol- rial Sloan-Kettering Cancer Center, 1275 York Avenue, New ogy; hematobogical malignancies; surgical oncology; pediatric York, NY 10021. Submit four original sets (not photocopies) of oncology; molecular oncology and cancer genes; , figures along with four copies of the manuscript. If a manuscript markers, and prognostic indicators; growth factors, cytokines, is closely related to papers that are in press or have been and signal transduction; bone marrow transplantation; gene ther- submitted elsewhere, please provide copies of those papers with apy; cancer endocrinology; cell adhesion, invasion, and metas- your submission. tasis; prevention of primary and recurrent cancer; differentiation Advances in Brief will be reserved for concise, definitive and cell death; clinical ; and detection of minimal dis- reports of novel observations and discoveries that have unusual ease. importance. A request for consideration for Advances in Brief should be included in the letter of submission. A Minireview is a brief analysis (typically 3-4 printed pages) of a focused, timely Editorial Policy research topic, aimed at a multidisciplinary audience. Minire- When a manuscript is received for consideration, the Editors views and Controversies in Clinical Cancer Research that are assume that no similar paper has been or will be submitted for submitted or solicited will undergo editorial review. The Editors publication elsewhere. Further, it is understood that all authors welcome Letters to the Editor, which will be published if they listed on a manuscript have agreed to its submission. The are determined to be appropriate. signature of the corresponding author on the letter of submission The letter of submission should suggest the Associate signifies that these conditions have been fulfilled. Editor (or Editor-in-Chief) who will serve as primary reviewer Journal policy requires that authors, reviewers, and Asso- of the manuscript. In addition, we invite authors to provide the ciate Editors reveal in a letter to the Editor-in-Chief any rela- names, addresses, and telephone/fax numbers of up to five tionships that they have that could be construed as causing a potential reviewers who are not current or recent collaborators conflict of interest with regard to a manuscript under review. or advisors in the area under investigation. The letter should include a statement of any financial relation- For both original and revised submissions, we cannot guar- ships with commercial companies involved with a product under antee that manuscripts and illustrations will be returned to the study. author. Upon acceptance, authors must transfer copyright to the American Association for Cancer Research, Inc., the copyright Format owner of the journal, prior to publication. The Editors endorse Manuscripts must be written succinctly in clear, grammatical the principles embodied in the Declaration of Helsinki and English. Define abbreviations in an inclusive footnote to the expect that all investigations involving humans will have been text. Double-space on 8 1/2 x 1 1-inch paper. Dot-matrix printing performed in accordance with these principles. To obtain a copy is not acceptable. The format is as follows: of the Helsinki Declaration, please contact the World Medical Association, 28, Ave. des Alpes, F-01210, Ferney-Voltaire, 1. Title page, including title, authors and their institutions, France. For animal experimentation reported in the journal, it is research support, and address plus telephone/fax numbers of expected that investigators will have observed the Interdisciplin- the corresponding author; ary Principles and Guidelines for the Use of Animals in Re- 2. A running title of fewer than 50 characters; search, Testing, and Education issued by the New York Acad- 3. Three to five key words that do not appear in the title; emy of Sciences’ Ad Hoc Committee on Animal Research, a 4. Abstract, of not more than 250 words, stating briefly the copy of which is available for $5.00 from the Marketing Dc- objectives, methods, results, and conclusions of the study; partment, New York Academy of Sciences, 2 East 63rd Street, 5. Text arranged in this order: Introduction, Methods, Results, New York, NY 10021-7289. All human and animal studies must Discussion, Acknowledgments, References; ii Instructions for Authors

6. Footnotes, on a page separate from the text. Designate foot- the author requests a greater width. Use tissue overlays to notes consecutively with superscript Arabic numerals; indicate important areas of the photographs that must be repro- 7. Tables, on pages separate from the text, with descriptive duced with greater fidelity. titles and legends that make the data understandable without Authors are encouraged to submit color figures. The cx- reference to the text; pense of reproducing color photographs must be offset partially 8. Figure legends, on pages separate from the text, with descrip- by the author. In 1996, the cost of color reproduction charged to tive titles and explanations to make the data understandable authors will be $975 per color figure. Submit color figures on without reference to the text. Define all symbols and include flexible backing. staining for halftones where applicable; 9. Figures.

Proofs Page proofs must be returned to the office of the American References Association for Cancer Research within 24 hours of receipt. Include only those articles that have been published or are in Return proofs by overnight mail. Proofs not received by the press. Unpublished data or personal communications must be deadline will be published without the authors’ corrections. cited as footnotes to the text. Personal communications should Accepted manuscripts are regarded as final copy and should not be substantiated by a letter of permission. Number references in be altered substantially in proof. Extensive alterations could the order of their first mention in the text. Cite only the number cause publication delays, and authors will be charged for exces- assigned to the reference. References must be double-spaced. sive alterations in proof.

SAMPLE REFERENCES: Typesetting Manuscripts from Computer Disks 1. Shaffer, D. W., Smith, L. S., Bums, H. A., Clark, G. M., Eckardt, J. R., Fields, S. M.. Weiss, G. R., Rinaldi, D. A., Bowen, K. J., Kuhn, Clinical Cancer Research welcomes disks to expedite produc- J. G., and Von Hoff, D. D. A randomized phase I trial of chronic oral tion of accepted manuscripts. If your article is accepted for etoposide with or without granubocyte-macrophage colony-stimulating publication, you will receive instructions regarding disk submis- factor in patients with advanced malignancies. Cancer Res., 53: 5929- 5933, 1993. sion. It is the author’s responsibility to ensure that the material 2. Dimaggio, J. J., Scheinberg, D. A., and Houghton, A. N. Monoclonal on the disk matches the final accepted version of the manuscript. antibody therapy of cancer. In: H. M. Pinedo, B. A. Chabner. and D. L. Longo (eds.), Cancer Chemotherapy and Biological Response Modifiers Annual, Vol. II, pp. 177-203. Amsterdam: Elsevier Science Publishers B. V., 1990. For more information, contact:

John Mendelsohn, M.D., Editor-in-Chief, Clinical Cancer Re- Figures search, Department of Medicine, Memorial Sloan-Kettering Provide four original sets of figures (whether line-cut draw- Cancer Center, 1275 York Avenue, New York, NY 10021, ings or halftones). Each sorted set should be in a separate Telephone 21 2-639-63 17, Fax 212-717-3629

labeled envelope, for distribution to reviewers. A typed label or: placed on the reverse side of each figure should contain the first author’s name, figure number, and an arrow indicating Publications Department, American Association for Cancer Re- top of figure. Letters and numbers on figures should not be search, Public Ledger Building, Suite 816, 150 South Indepen- smaller than 6-point or larger than 12-point type. All figures will dence Mall West, Philadelphia, PA 19106-3483, Telephone be published at a width of approximately 3 inches (8 cm) unless 215-440-9300, Fax 215-440-9355. AMERICAN ASSOCIATION FOR CANCER RESEARCH

GUIDELINES FOR APPLICATION FOR ACTIVE AND CORRESPONDING MEMBERSHIP

BENEFITS OF MEMBERSHIP Receipt of Application in AACR Office ______Notification of Candidate The American Association for Cancer Research (AACR). a scientific society of over 10,000 laboratory and clinical cancer researchers, was January 1 March May 1 July founded in 1907 to facilitate communication and dissemination of knowl- September 1 November edge among scientists and others dedicated to the cancer problem; to foster research in cancer and related biomedical sciences; to encourage the A complete application consists of the following material: presentation and discussion ofnew and important observations in the field: 1 . 6 copies of the form on the opposite side of this page. with all requested to foster public education, science education, and training; and to advance information provided. the understanding of cancer etiology, prevention, diagnosis, and treatment 2. 5 copies of the candidate’s most current curriculum vitae and bibliog- throughout the world. raphy. Members of the AACR enjoy the following benefits: 3. 5 copies of a letter of recommendation from a nominator who is an I . the privilege of sponsoring a proffered paper (abstract) for consider- active, corresponding, emeritus, or honorary member of the AACR (at ation for presentation at the AACR annual meeting; least one copy must be a signed. original letter). This letter should 2. an advance copy of the Program and Proceedings of the American describe the candidate’s achievements in laboratory research, clinical Association for Cancer Research pertaining to each annual meeting: investigations, or epidemiological research, and it should affirm that 3. reduced registration rates at annual meetings; this research adheres to accepted ethical scientific standards. -OR- The 4. priority notice of small, focussed meetings in the AACR’s exciting nominator may supply the responses requested at the bottom of the series of Special Conferences in Cancer Research; application form in the section entitled “STATEMENT OF SUP- 5. reduced registration rates for Special Conferences; PORT” (at least one copy of the form must be the signed original). 6. opportunities for participation in AACR meetings in North America 4. 5 copies of a letter of recommendation as described in Item 3 above and abroad with other scientific societies around the world; from a seconder who is an active, corresponding, emeritus, or honorary 7. receipt of AACR Newsletters and other important announcements: member of the AACR (at least one copy must be a signed. original 8. early notification of and reduced rates for participation in the AACR letter). -OR- The seconder may supply the responses requested at the Employment Register; bottom of the application form in the section entitled “STATEMENT 9. an up-to-date Membership Directory of thousands of researchers in OF SUPPORT” (at least one copy of the form must be the signed the cancer field; original). 10. the professional benefits of the AACR’s public education activities 5. 5 reprints of each of two publications on which the candidate appears concerning funding for cancer research and press coverage of the as author. As noted above, evidence of patents developed by the latest research findings; candidate may be submitted in lieu of one or both of the publications. I 1 . participation in Summer Workshops that foster networking opportu- If submitting patents, supply patent number and year awarded. and science education for young investigators; and nities All material should be collated into five complete sets with the original 12. many more ongoing benefits. application form as a covering document and sent to the address given below. Questions regarding procedures for membership application may QUALIFICATIONS FOR MEMBERSHIP also be directed to the following address: American Association for Cancer Research Active membership in the AACR is open to investigators who live in Public Ledger Building, Suite 816 the Americas. Individuals who have conducted two years of research 150 S. Independence Mall West resulting in peer-reviewed publications relevant to cancer, or who have Philadelphia, PA 19 106-3483 made substantial contributions to cancer research in an administrative or Phone: 215/440-9300 educational capacity, are eligible. If a candidate has conducted research in FAX: 215/440-9313 an area of biomedical science related to cancer, he or she will qualify for membership. Evidence of patents relevant to cancer research may be submitted as qualifications for membership in lieu of peer-reviewed pub- lications. RESPONSIBILITIES OF MEMBERSHIP Corresponding membership is open to persons who are not residents of the Americas. The qualifications for corresponding membership are the Candidates should be aware of the following responsibilities of mem- same as those indicated above for active membership. Visiting scientists bership in the AACR. Active members must pay annual dues. In 1996 from outside the Americas who intend to return to their countries of origin annual dues for active members are $160, $95 of which is designated for by the anticipated time of election should apply for corresponding mem- AACR journal subscriptions. Newly elected members of the AACR who bership. All other visiting scientists should apply for active membership have already purchased subscriptions to (‘ancer Research, Clinical (‘an- and transfer to corresponding status upon leaving the Americas. cer Research, Cell Gross’th & Differentiation, or (‘ancer Epidemiology, Graduate and medical students, postdoctoral fellows, and physicians in Bio,narkers & Prevention at the higher, nonmember rates will receive training who do not yet meet the above qualifications for active or reimbursement of the unused portion of those subscriptions once their first corresponding membership should apply for associate membership. year’s membership dues are paid in full. Forms for associate membership are available from the AACR Office. Corresponding members are required to pay dues ($80 in 1996) and may, if they wish, subscribe to Cancer Research, Clinical Cancer Re- search, Cell Growth & Differentiation, or Cancer Epidemiology, Biomar- PROCEDURES FOR APPLICATION kers & Prevention at reduced member rates. There are three deadlines for the receipt of a membership application: Applicants elected in March will be responsible for payment of that January 1, May I, and September 1 of each year. The Membership year’s dues; applicants elected in July and November will pay dues for the Committee will review all complete applications for active membership following year. Applicants elected in March and July will be eligible to that have been received by these deadlines and will submit recommenda- sponsor an abstract for the next annual meeting. Every effort will be made tions on each candidate to the Board of Directors which formally elects all to afford the same opportunity to applicants elected in November. members. The same procedure is followed by the Special Memberships Committee which receives applications for corresponding membership. Margaret Foti, Ph.D. Candidates will be notified according to the following schedule: Executive Director AMERICAN ASSOCIATION FOR CANCER RESEARCH, INC.

Public Ledger Building . Suite 816 . 150 S. Independence Mall West ‘ Philadelphia, PA 19106-3483

APPLICATION FOR ACTIVE OR CORRESPONDING MEMBERSHIP

NAME OF CANDIDiTP’ ‘ .______DATE OF BIRTH:______LAST FIRST MI.

PRESENT POSITION/TITLE: INSTITUTIONAL AFFILIATION:. INSTITUTIONAL ADDRESS:

(City) (State/Province) (Country) (Postal Code)

TELEPHONE NJ!‘ ‘ ‘.______TMRPR’ FAX NUMBER:______E-MAIL NUMBER (CARRIER):

PRIMARY FIELD OF RESEARCH (Please check only one): Biochemistry and Biophysics Biostatistics Biology and Genetics Investigations Endocrinology Epidemiology Immunology Biology and Genetics Pharmacology and Other:______Experimental Therapeutics (Please specify)

ACADEMIC DEGREES (Including where and when granted)

EXPERIENCE SINCE HIGHEST DEGREE WAS GRANTED (Please list most recent first)

PUBLICATIONS (Reprints of two peer-reviewed articles on which the candidate appears as an author must accompany this application. For these two articles list the authors, title, journal, volume, inclusive pages, and year. Do not submit abstracts. If submitting patents, supply patent number and year awarded.)

CANDIDATE CANDIDATE NOMINATED BY*: SECONDED BY* (Please print) (Please print)

CANDIDATE IS APPLYING FOR (Check one): E ACTIVE CORRESPONDING MEMBERSHIP

STATEMENT OF SUPPORT Instead of submitting letters of recommendation, either the nominator or the seconder or both may complete the following section:

How long has the candidate worked in the field of cancer re- How long has the candidate worked in the field of cancer re- search? years search? years Will the candidate make a long-term contribution to cancer re- Will the candidate make a long-term contribution to cancer re- search? Yes No search? Yes ...... No Does the candidate’s research adhere to accepted ethical stan- Does the candidate’s research adhere to accepted ethical stan- dards? ...Yes ..No dards? ...Yes ..No I therefore recommend this candidate for membership in the American I therefore recommend this candidate for membership in the American Association for Cancer Research. Association for Cancer Research.

Signature of nominator* Date Signature of seconder* Date

See Guidelines for Application on the reverse side of this form for further instructions.

*Both nominator and seconder must be active, corresponding, emeritus, or honorary members of the AACR.

(This form may be reproduced.) AMERICAN ASSOCIATION FOR CANCER RESEARCH

IGUIDELINES FOR APPLICATION FOR ASSOCIATE MEMBERSHIP

QUALIFICATIONS FOR MEMBERSHIP and the nominator. The application form may be submitted to the Asso- Associate membership is open to graduate students, medical students, ciation Office at any time. postdoctoral fellows, and physicians in training who are following a course of study or who are working in a research program relevant to After review of applications for associate membership, the Executive cancer. Scientists in training who already have a substantial record of Director will notify candidates of their election or deferral within one publications may wish to apply for active or corresponding membership month of the receipt of the application form. A check for one year’ s dues which confers full benefits of membership. payment must accompany the application. Dues are currently $35 for associate members residing in the Americas and $45 for residents of other countries. This fee will be refunded to any candidate deemed to be BENEFITS OF MEMBERSHIP ineligible for associate membership. Checks should be in U.S. currency, The American Association for Cancer Research (AACR), a scientific made payable to AACR, Inc., and drawn on a U.S. bank. Send the three society consisting of laboratory and clinical cancer researchers, was copies of the application form and the $35 or $45 dues payment to: founded in 1907 to facilitate communication and dissemination of knowl- edge among scientists and others dedicated to the cancer problem; to foster American Association for Cancer Research research in cancer and related biomedical sciences; to encourage presen- Public Ledger Building, Suite 816 tation and discussion of new and important observations in the field; to 150 5. Independence Mall West foster public education, science education, and training; and to advance the Philadelphia, PA 19106-3483 understanding of cancer etiology, prevention, diagnosis, and treatment 215/440-9300 throughout the world. Associate members of the AACR enjoy the follow- ing benefits: RESPONSIBILITIES OF MEMBERSHIP 1 . the privilege of sponsoring a paper for presentation at the AACR annual meeting provided that (a) the associate member is the presenter Associate members must pay annual dues in an amount to be deter- of the paper and (b) an active, corresponding, emeritus, or honorary mined by the AACR Board of Directors. Dues for 1995 and 1996 have member in good standing of the AACR also signs the abstract of the been set at $35 per year for residents of the Americas and $45 for residents paper in support of the work (In this instance, the member who cosigns of other countries. If an application is submitted by August 3 1, the the abstract does not lose his or her own sponsorship privilege.); accompanying dues payment will be credited to the current year. Candi- 2. an advance copy of the scientific Program and (if one has been dates submitting applications between September 1 and December 3 1 may purchased by the associate member) the Proceedings of the American indicate whether they wish their dues payments credited to the current or Associationfor Cancer Research which contains abstracts of all papers forthcoming year. Candidates should be aware, however, that associate being presented at each annual meeting; members may sponsor an abstract for the annual meeting only if their dues 3. the privilege of registering for the annual meeting at the low student for the current year are paid. For example, an associate member submitting rate (This rate is otherwise available only to predoctoral students.); an abstract in November 1995 for the forthcoming annual meeting must 4. preferred access to the AACR Employment Register; have paid dues for 1995. Any newly elected associate members of the 5. optional subscriptions to the Association’s high-quality journals Can- AACR who have already purchased subscriptions to Cancer Research, cer Research, Clinical Cancer Research, Cell Growth & Differentia- Clinical Cancer Research, Cell Growth & Differentiation, or Cancer tion, and Cancer Epidemiology, Biomarkers & Prevention at reduced Epidemiology, Biomarkers & Prevention at the higher, nonmember rate member rates; will receive a refund for the unused portion of that subscription upon 6. priority notification of events in the AACR’s series of special confer- receipt of their payment for a member’s subscription. ences on timely subjects in the field; Each Fall the AACR will send to current associate members an invoice 7. reduced registration rates at special conferences; for dues for the forthcoming year. Payment of this invoice must be 8. the receipt of AACR newsletters, meeting announcements, and an accompanied by a statement signed by the associate member’s current up-to-date membership directory; and registrar, dean, or department head, verifying the member’ s current aca- 9. the facilitation of informal scientific exchange with leading researchers demic status. The Association’s By-Laws state that dues are payable for in the cancer field. each year in advance by January 1 of the year to which they should be applied. An individual may be an associate member for a maximum of five years. Each year in which an individual pays dues will count as one full PROCEDURES FOR APPLICATION year of associate membership. Thus, an associate member who pays dues Persons wishing to apply for associate membership must use the offi- for 1995 may retain associate membership until December 3 1 , 1999. The cial application form on the reverse side of these instructions. Each Board of Directors may terminate the membership of an associate member candidate for associate membership must be nominated by an active, whose dues are in arrears for two years. corresponding, emeritus, or honorary member in good standing of the AACR. Three completed copies of the form should be submitted; at least Margaret Foti, Ph.D. one of these copies must carry the original signatures of both the candidate Executive Director AMERICAN ASSOCIATION FOR CANCER RESEARCH, INC. Public Ledger Building . Suite 816 ‘ 150 S. Independence Mall West Philadelphia, PA 19106-3483 P APPLICATION FOR ASSOCIATE MEMBERSHIP

NAME OF CANDIDATE:______DATE OF BIRTH:______LAST FIRST MI. INSTITUTIONAL AFFILIATION:______INSTITUTIONAL ADDRESS:

(City) (State/Province) (Country) (Postal Code)

TELEPHONE NUMBER:______- FAX NUMBER:______

PRESENT ACADEMIC STATUS/TITLE (Please check only one): E-MAIL NUMBER (CARRIER): ______Graduate Student ______Medical Student Physician in Training Postdoctoral Fellow

PRIMARY FIELD OF RESEARCH (Please check only one): Biochemistry and Biophysics ______Biostatistics Carcinogenesis ______Cellular Biology and Genetics ______Clinical Investigations Endocrinology Epidemiology Immunology ______Molecular Biology and Genetics ______Preclinical Pharmacology and Virology flthr Experimental Therapeutics (Please specify)

ACADEMIC DEGREES (Please indicate degree(s) acquired to date along with the name ofthe academic institution and date ofreceipt. Provide information on degree currently being sought and the anticipated date of completion of this degree program.)

RELEVANT RESEARCH EXPERIENCE NOT RELATED TO COURSE WORK (Please list most recent first.)

PUBLICATIONS (List the authors, title. journal, volume, inclusive pages, and year of any article in a peer-reviewed journal on which the candidate appears as an author. Do not list abstracts. Continue on a separate sheet, if necessary.)

CANDIDATE NOMINATED BY:. (Please type or print name of AACR member* in good standing.) SIGNATURES I hereby apply for associate membership in the American Association for Cancer Research. I have read the instructions on the reverse side of this form, and I understand the privileges and responsibilities of this class of membership. I certify that the statements on this application are true.

Signature of Candidate:.

I recommend this candidate for associate membership in the American Association for Cancer Research. To the best of my knowledge, the candidate is qualified for this class of membership, and the statements on this application are true.

Signature of Nominator*: Date:

Submit three copies of this form. At least one copy must contain the original signatures of the candidate and the nominator. Enclose a check in U.S. funds. made payable to AACR. Inc., and drawn on a U.S. bank for one year’s dues. Dues are currently $35 for associate members residing in the Americas and $45 for residents of other countries.

Check one of the following boxes only if this form is being submitted between September 1 and December 3 1: The enclosed dues payment should be applied to the fl current forthcoming calendar year.

(NOTE: If dues are applied to the forthcoming year, membership will take effect on January 1 , but the candidate will not be eligible to sponsor an abstract for presentation at the annual meeting in March on April of that year.) See Guidelines for Application on the reverse side of this form for further instructions.

*Nomjnator must be active, corresponding, emeritus, or honorary member of the AACR.

(This form may be reproduced.) Guidelines for Submitting Disks to American Association for Cancer Research Publications

The word processing packages that we prefer are as follows:

MacWrite WordPerfect (DOS, Windows, Microsoft Word (DOS, Windows, and Macintosh) and Macintosh) XyWrite (DOS and Windows)

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Software packages that we are unable to translate:

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This form (both sides) may be reproduced. AMERICAN ASSOCIATION FOR CANCER RESEARCH ut,i::,=._,( SCIENTIFIC CONFERENCES

‘\O

OCTOBER 19-23, 1996 FEBRUARY 19-25, 1996 Cancer Susceptibility Genes and Programmed Cell Death Chairperson: Stanley J. Korsmeyer, St. Louis, MO Molecular Carcinogenesis The Sagamore, Bolton Landing (Lake George), NY Chairpersons: Curtis C. Harris, Bethesda, MD; Allan Balmain, Glasgow, Scotland; Kenneth Olden, Research Triangle Park, NC JANUARY 10-14, 1997 Keystone Resort, Keystone, CO Basic and Clinical Aspects of Lymphoma Joint Meeting with the American Society of Clinical MARCH 1-5, 1996 Oncology Proteases and Protease Inhibitors Chairpersons: Joseph R. Bertino, New York, NY; Chairpersons: Lynn M. Matrisian, Nashville, TN; James 0. Armitage, Omaha, NE Bonnie F. Sloane, Detroit, Ml Stouffer Renaissance Esmeralda Resort, Indian Marriott’s Bay Point Resort, Panama City Wells (Palm Springs), CA Beach, FL

APRIL 20-24, 1996 JANUARY 17-21, 1997 87th Annual Meeting Disrupted Transcription Factors in Cancer Chairperson: Lorraine J. Gudas, New York, NY Chairpersons: Peter K. Vogt, La Jolla, CA; Frank Washington D.C. Convention Center, J. Rauscher Ill, Philadelphia, PA Washington, D.C. Hotel Del Coronado, San Diego, CA Abstract Deadline: December 1, 1995

JUNE 8-12, 1996 FEBRUARY 13-16, 1997 Inducible Genomic Responses Growth Factors, Signaling, and Cancer Chairpersons: William T. Beck, Memphis, TN; Joint Meeting with Lorne Cancer Congress John A. Hickman, Manchester, England; Chairpersons: Antony Burgess, Parkville, Victoria, Richard I. Morimoto, Evanston, IL Australia; Robert S. Coffey, Nashville, TN; Skamania Lodge, Stevenson (Columbia River Ashley R. Dunn, Parkville, Victoria, Australia; Gorge), WA Webster K. Cavenee, La Jolla, CA Erskine House, Lorne, Victoria, Australia OCTOBER 2-6, 1996 Novel Approaches in Blood and Marrow Transplantation Second Annual Meeting of the American Society for Blood and Marrow Transplantation Chairpersons: 0. Michael Colvin, Durham, NC; AACR members will receive brochures on the Bruce R. Blazar, Minneapolis, MN above special conferences as soon as they are Hotel Del Coronado, San Diego, CA available. Nonmembers should call or write:

OCTOBER 6-9, 1996 American Association for Cancer Research Carcinogenesis from Environmental Public Ledger Building, Suite 816 150 South Independence Mall West Pollution: Assessment of Human Risks Philadelphia, PA 19106-3483 and Strategies for Prevention 21 5-440-9300 #{149} 21 5-440-931 3 (FAX) Joint Meeting with International Agency for E-Mail: [email protected] Research on Cancer Chairpersons: Frederica Perera, New York, NY; Paul Kleihues, Lyon, France Hotel Gell#{233}rt,Budapest, Hungary METHODS WORKSHOPS

87th AACR Annual Meeting Washington DC Convention Center Saturday, April 20, 1996, 2:00-6:00 p.m.

Two state-of-the-art methods workshops will be offered simultaneously during the upcoming annual meeting. A registration fee of $50.00 for members and predoctoral students, and $75.00 for nonmembers will be charged.

The intent of these sessions is to provide a detailed description of new research techniques and to illustrate their potential for cancer research. Registrants in each session will receive a handout including a selected bibliography of highly relevant articles. The American Society of Clinical Oncology designates this continuing medical education activity for 4 credit hours in Category 1 of the Physician’s Recognition Award of the American Medical Association.

Methods Workshop 1 Quantitative Biology and Pharmacodynamics

Chairperson ROBERT C. JACKSON, Agouron Pharmaceuticals, Inc., San Diego, CA

This workshop attempts to give attendees a working acquaintance with several computational pharmacology techniques that are valuable in making drug development decisions, in designing clinical trials, and in gaining quantitative insights into drug action. The methods to be discussed will include physiologically-based pharmacokinetic modeling (and its use in predicting human pharmacokinetics from preclinical data), pharmacodynamic modeling, quantitation and statistical evaluation of synergistic and antagonistic drug interactions, and the use of biochemical pathway simulations and cytokinetic models to predict the development of drug resistance. In each case the emphasis will be on the computational techniques and data analysis, rather than on data acquisition. The presentations will discuss the use of commercially available or public domain software, and participants are encouraged to bring portable computers to work out examples onsite. Programming experience, although helpful, is not essential.

Program

Physiologically-based Pharmacokinetic Modeling and Interspecies Scaling. Robert L. Dedrick, National Center for Research Resources, Bethesda, MD. Pharmacodynamic Modeling. Mark J. Ratain, University of Chicago, Chicago, IL. Quantitation of Synergism and Antagonism. William R. Greco, Roswell Park Cancer Institute, Buffalo, NY. Modeling the Development of Drug Resistance. Robert C. Jackson.

Methods Workshop 2 Methods of Tumor Suppression in Transgenic Models of Tumorigenesis

Chairperson TERRY VAN DYKE, University of North Carolina, Chapel Hill, NC

Program

The Use of Transgenic Mice in Cancer Research. Terry Van Dyke. Analysis of the Role ofp53 Loss in Tumor Progression Using p53-Deficient Mice. Lawrence A. Donehower, Baylor College of Medicine, Houston, TX. Genetic Approaches to Studying BRCAJ Function in Mice. Beverly Koller, University of North Carolina, Chapel Hill, NC. Title to be Announced. Earl Ruley, Vanderbilt Cancer Center, Nashville, TN. REGISTRATION FORM METHODS WORKSHOPS 1 AND 2 87th Annual Meeting April 20, 1996, 2:00-6:00 p.m.

PLEASE TYPE OR PRINT INFORMATION REQUESTED BELOW Persons wishing attend a methods workshop must be registered for the AACR Annual Meeting and must pay an additional fee of

$50.00 for members and predoctoral students, and $75.00 for nonmembers.

1. SELECT SESSION: Check the box next to the one methods workshop you wish to attend. You may attend only the session for which you are registered.

0 Methods Workshop 1: Quantitative Biology and Pharmacodynamics. Robert C. Jackson, Chairperson. (Note: If you check this box, please complete Section 5 below as well.)

0 Methods Workshop 2: Methods ofTumor Suppression in Transgenic Models ofTumorigenesis. Terry Van Dyke, Chairperson. (Note: If you check this box, please complete Section 6 below as well.)

2. NAME: Last First M.I.

3. ADDRESS: Institution

Street, Building, or P.O. Box

City State or Province Postal Code

Country Telephone FAX

4. PAYMENT (check 1): 0 My fee has been added to the attached annual meeting registration form. 0 I have already registered for the meeting and enclose a check for $50 (members and predoctoral students) or $75 (nonmembers) 0 I have already registered for the meeting; charge my (check 1) 0 MasterCard 0 VISA 0 American Express 0 Eurocard Number: ______Exp. Date ______Signature:

5. SUPPLEMENTAL QUESTIONS FOR REGISTRANTS FOR METHODS WORKSHOP 1 ONLY:

A. Are you involved in preclinical or clinical research with anticancer drugs? Yes No

B. Do you have a basic knowledge (at least) of statistics? Yes No

C. Do you have a basic knowledge (at least) of pharmacokinetics? Yes No

D. Do you have a basic level (at least) of computer literacy? Yes No

E. Do you have any programming experience? Yes No

6. SUPPLEMENTAL QUESTIONS FOR REGISTRANTS FOR METHODS WORKSHOP 2 ONLY:

A. Do you have hands-on experience with any of the following? i. culturing mouse embryonic stem cells Yes No ii. generating mouse chimeras Yes No iii. design of targeted mutagenesis vectors Yes No iv. generation of transgenic mice through pronuclear injections Yes No v. mouse genome/gene mapping strategies? Yes No vi. in situ detection within tissues? Yes No

B. What is the current status of mouse related technologies in your lab? (check 1 only)

- ongoing, active, and successful; which specific area?______

- in initial stages of establishment

- not yet part of my program

C. What are the areas in which you most need practical information? (check all that apply)

- how to make standard targeted mutations how to culture ES cells

- how to develop more specific targeted mutations - in situ technologies

- genome mapping techniques - how to make chimeras

- non-homologous transgenics - mouse data management

- other (Specify.)

THE DEADLINE FOR REGISTRATION BY MAIL IS MARCH 25, 1996 If space permits, registrations will be accepted after this date and at the annual meeting. CARCINOGENESIS FROM ENVIRONMENTAL POLLUTION: ASSESSMENT OF HUMAN RISK AND STRATEGIES FOR PREVENTION

Joint Meeting Organized by the American Association for Cancer Research (AACR) and the International Agency for Research on Cancer (IARC)

With the Collaboration of the Hungarian Cancer Society

, AS October 6-9, 1996 c- O Hotel Gell#{233}rt UCanum Budapest, Hungary

CONFERENCE CHAIRPERSONS c1 1907 kCER l Frederica Perera I New York, USA Paul Kleihues I Lyon, France

PROGRAM COMMITTEE

Hans-OIov Adami I Uppsala, Sweden Waun Ki Hong I Houston, USA J. Carl Barrett I Research Triangle Park, USA Margaret L. Kripke I Houston, USA Paolo Boffetta I Lyon, France Kenneth Olden I Research Triangle Park, USA Edward Bresnick I Worcester, USA Alan Pint#{233}rI Budapest, Hungary Mieczyslaw A. Chorzy I Gliwice, Poland Manfred F. Rajewsky I Essen, Germany Joseph F. Fraumeni, Jr. 1 Bethesda, USA David Zaridze 1 Moscow, Russia

SCIENTIFIC PROGRAM

Keynote Address Strategies for Prevention Curtis C. Harris I Bethesda, USA Waun Ki Hong I Houston, USA I. Bernard Weinstein I New York, USA Cancer Incidence and Etiology Anna Tompa I Budapest, Hungary Witold A. Zato#{241}skiI Warsaw, Poland Frederica Perera I New York, USA Roundtable Discussion J. Carl Barrett I Research Triangle Park, USA Paul Kleihues I Lyon, France Helmut Bartsch I Heidelberg, Germany Hans-OIov Adami I Uppsala, Sweden Paolo BoffettaI Lyon, France Air, Water, Food, and Soil Contamination Edward Bresnick I Worcester, USA Radim J. r#{225}mI Prague, Czech Republic Andrew E. Czeizel I Budapest, Hungary Joellen Lewtas I Research Triangle Park, USA Tern Damstra I Research Triangle Park, USA Wieslaw Jedrychowski I Cracow, Poland Edith OIah I Budapest, Hungary OIav Axelson I LinkOping, Sweden Kenneth Olden I Research Triangle Park, USA Manfred F. Rajewsky I Essen, Germany Ambient, Environmental, and Occupation Exposure William A. Suk I Research Triangle Park, USA and Cancer Risk David Zaridze I Moscow, Russia Mieczyslaw A. Chorzy I Gliwice, Poland Alan Pint#{233}rI Budapest, Hungary Applicants are encouraged to submit abstracts Kimmo Peltonen I Helsinki, Finland for poster presentation. Monica C. Hollstein I Heidelberg, Germany Kari Hemminki I Stockholm, Sweden Information and Application Forms

Tobacco American Association for Cancer Research Ivan Plesko I Bratislava, Slovakia Public Ledger Building, Suite 816 Barbara S. Hulka I Chapel Hill, USA 150 S. Independence Mall West I Italy Paolo L. Vineis Turin, Philadelphia, PA 19106-3483 Stephen S. Hecht I Valhalla, USA (21 5) 440-9300 (21 5) 440-931 3 (FAX) Krystyna Frenkel I New York, USA Email: [email protected] Bernadette Schoket I Budapest, Hungary The American Association for Cancer Research Presents

Molecular Biology in Clinical Oncology: A Workshop

Supported by a Generous Grant from the National Cancer Institute

An intensive, one-week summer workshop on molecular June 28-July 4, 1996 biology designed for clinical oncologists in training Given Biomedical Institute or in their early academic careers. Aspen, Colorado

ORGANIZERS

STEPHEN H. FRIEND L. MICHAEL GLODE JENNIFER A. PIETENPOL Fred Hutchinson Cancer University of Colorado Vanderbilt University Research Center School of Medicine School of Medicine Seattle, WA Denver, CO Nashville, TN

#{149}Lectures by leading experts on molecular biology concepts and the latest developments in molecular oncology. Topics include gene therapy, oncogenes and growth factors, tumor suppressor genes, molecular genetics, metastasis genes, and drug design.

#{149}Small group laboratory sessions to demonstrate the important experimental techniques utilized in molecular biology.

#{149}Category I CME credits through the University of Colorado School of Medicine.

#{149}A workshop syllabus containing relevant published papers, references to key articles in the literature, and details on important laboratory procedures.

#{149}Financial support for participants who are physicians in training or oncology fellows.

Faculty

Lectures

ANDRE BERNARDS/ Charlestown, MA LELAND H. HARTWELL/ Seattle, WA GARY J. NABEL/ Ann Arbor, MI KATHLEEN it CHO/ Baltimore, MD TYLER JACKS/ Cambridge, MA ALLEN I. OLIFF/ West Point, PA CYNTHIA A. EDWARDS/ Redwood City, CA MARY.CLAIRE KING! Seattle, WA JENNIFER A. PIETENPOL’ Nashville, TN ROBERT N. EISENMAN/ Seattle, WA RICHARD D. KLAUSNER/ Bethesda, MD NADIA ROSENTHAIJ Charlestown, MA ERIC R. FEARON/ Ann Arbor, MI MARC E. LIPPMAN/ Washington, DC PATRICIA S. STEEG/ Bethesda, MD STEPHEN H. FRIEND/ Seattle, WA A. THOMAS LOOK/ Memphis, TN MIN WU/ Beijing, P. R. C. HAROLD L MOSES/ Nashville, TN

Laboratory Rotations

MARK S. BOGUSKI/ Bethesda, MD. “Computer Searching in Molecular Biology.” JULIE A. CAMPAIN/ Denver, CO. ‘Polymerase Chain Reaction Technology.” JAMES P. HOEFFLER/ San Diego, CA. ‘fransfer of Nucleic Acids and Proteins.” MARILEILA V. GARCIA/ Denver, CO. “Practical Cytogenetics.” CORI GORMANlBurlingame, CA. “Gene Expression Systems.”

Application Deadline March 25, 1996

For further information, contact

American Association for Cancer Research Public Ledger Building, Suite 816 150 S. Independence Mall West Philadelphia, PA 19106-3483

Telephone: (215) 440-9300 #{149} FAX: (215) 440-9313 Email: [email protected] ADVANCE REGISTRATION FORM

AMERICAN ASSOCIATION FOR CANCER RESEARCH

87TH ANNUAL MEETING - WASHINGTON, DC - April 20-24, 1996

Return to

American Association for Cancer Research #{149}Public Ledger Building, Suite 816

150 5. Independence Mall West #{149}Philadelphia, PA 19106-3483 #{149}FAX: 215-440-7228

DEADLINES: #{149}March 1, 1996 for reduced rates and to ensure receipt of meeting materials by mail in late March or early April #{149}March 25, 1996 for all registration by mail (Registration forms received after this date will not be accepted. Registration will be conducted at the Washington Convention Center from April 20-24.) #{149}April 17, 1996 to cancel registration and receive refund less cancellation fee ($35)

(Please print)

NAME: ______Last FirstlMiddtc Initial AACR Mcmhcr Numhcr

TITLE: ______ADDRESS: ______Institution

Street, Building. (‘ Post Office Box

City State or Province Zip/Postal Code Country (if not U.S.)

TELEPHONE NO.: ______FAX NO.: ______

0 Check this box if you have a physical disability and have special requirements for transportation, hotel accommodations, or other facilities in connection with the meeting. A member of the Association Staff will contact you. WHAT IS YOUR PRIMARY FIELD OF RESEARCH (Please check only one):

0 Biochemistry and Biophysics 0 2Carcinogenesis 0 ‘Cellular Biology & Genetics 0 4Clinical Investigations 0 5Endocrinology 5Epidemiology 7Experimental Therapeutics 0 5lmmunology 0 9Molecular Biology & Genetics 0 ‘‘Prevention tRadiobiology/Radiation Oncology 0 ‘2Virology 0 ‘Other (please specify): ARE YOU THE PRESENTER OF AN ABSTRACT SUBMITTED FOR THE 1996 AACR MEETING? 0 Yes 0 No ON WHICH DAYS WILL YOU A1TEND THE 1996 AACR ANNUAL MEETING? 0 Saturday. April 20 0 Sunday, April 21 0 Monday, April 22 0 Tuesday, April 23 0 Wednesday, April 24

PAYMENT OF REGISTRATION Fees may be paid by check or with a MasterCard, VISA, American Express, or Eurocard account. All payments must be made in U.S. currency, and all checks IlluSt be drawn on a U.S. bank. Payment must accompany this form; purchase orders will not be accepted as payment. On or Before After March 1 March 1 METHOD OF PAYMENT 0 Active/Corresponding Member Rate $135 $170 OCheck payable to AACR, Inc. in U.S. currency, drawn on a 0 Nonmember Rate $270 $340 U.S. bBk (includes copy of AACR Proceedings) 0 Emeritus Member Rate $ 50 $ 5() . D Person/Institution Issuing Cheek Check No. Associate Member Rate $ 75 $ 85 0 Predoctoral Student Rate5 $ 60 $ 70 0 Honorary Member Rate $ 0 $ 0 0 AACR proceeding.cc $ 35 Members $ 35 Members 0 MasterCard 0 VISA 0 American Express 0 Eurocard $ 45 Nonmembers $ 45 Nonmembers 0 Optional Overseas Surcharged $ 25 NA. 0 Proceedings on CD-ROM $ 35 Members $ 35 Members Card Number Expiration Date $ 45 Nonmembers $ 45 Nonmembers 0 Methods Workshop Registration $ 50 Members $ 50 Members $ 75 Nonmembers $ 75 Nonmembers ______Signature

TOTALENCLOSEDORCHARGED $______$______

An application for Associate Membership may accompany this form. but these should be submitted well before the March 1 deadline, as review of the Associate Membership application may delay registration. 5Sttidents must enclose a statement, signed by the registrar, dean, or department head of their university or college on official letterhead, confirming their status. Postdoctoral fellows or physicians in training do not qualify for the student registration rate. ‘AACR members with paid-up subscriptions to an AACR journal and registrants who pay the nonmember fee receive the Proceedings automatically. If these members or nonmembers check this box and pay the fee, they will receive an additional copy of the Proceedings. ‘Optional payment for registrants outside of the U.S. and Canada only. Registrants paying this surcharge will receive meeting publications via an’mail--printed matter before the annual meeting. This service not available after March 1.

AACR members in good standing will receive copies of the Program and Proceedings prior to the meeting. Nonmember and student registrants who meet the March 1 deadline will also receive the Program and (if they have purchased it) the Proceedings prior to the meeting. Nonmembers and students who do not meet the deadline must pick up publications at the oseeting site. REFUND POLICY Refunds on registration fees will be granted on written request received in the AACR Office by April 17, 1996. Requests received after this date will not be honored. Receipts and badges (if they have been mailed) must be returned to the AACR Office with the refund request. A cancellation fee of $35 will be deducted from all refunds to cover administrative costs.

(This form may be reproduced.) ORDER TODAY! Don’t miss a single issue ofthe latest clinical and translational research! Clinical Cancer Research

An official journal oftheAmerican Association for CancerResearch

ORDER FORM: Yes! I’d like to subscribe! A Monthly Journal Clinical Cancer Researth Method of Payment Vol. 2, 1996, 12 issues, ISSN 1078-0432 El Enclosed check or money order in U.S. dollars drawn featuring the most innovative Institutional (Available only as a combined subscription on u.s. bank. Payable to American Association for with Cancer Research) Cancer Research. clinical research and El $595 El Institutional purchase order #______translational research bridging El $130 should be added for delivery outside the U.S. is enclosed Individual El Please charge my El Mastercard El VISA the laboratory and the clinic. El $95 El American Express El $40 should be added for delivery outside the U.S. Editor-in-ChieJ AACR Members: Contact the AACR for rates, (215) 440-9300. Canada: Add 7% GST. MD: Add state sales tax. ACCOUNTNAME John Mendelsohn, Individual Subscriber: I certify that this subscription is solely for my personal use and will not be ACCOUNT NO M.D. used in a library.

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-.- Clinical - Cancer bO1\ Research

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NO POSTAGE NECESSARY IF MAILED HH IN THE UNITED STATES A Monthly Journal featuring the most innovative BUSINESS REPLY MAIL clinical research and FIRST CLASS PERMIT NO. 724 EASTON, MD translational research bridging POSTAGE WILL BE PAID BY ADDRESSEE the laboratory and the clinic. CLINICAL CANCER RESEARCH P0 BOX 3000 Editor-in-Chiej DENVILLE NJ 07834-9359 John Mendelsohn, M.D. Memorial Sloan-Kettering Cancer Center III...I...II..I...II.11..II.I.11#{149}II..I.I.I.I..11h11 Subscribe Now! Every issue is essential

NO POSTAGE reading. NECESSARY IF MAILED Call 1-800-875-2997 H IN THE UNITED STATES or 201-627-2427, or mail back the attached BUSINESS REPLY MAIL order card. FIRST CLASS PERMIT NO. 724 EASTON, MD No-Risk Guarantee: POSTAGE WILL BE PAID BY ADDRESSEE If you are not entirely CLINICAL CANCER RESEARCH satisfied with this journal, P0 BOX 3000 DENVILLE NJ 07834-9359 you will receive a refund for any unmailed issues on your subscription.

IIIiiiI.i.III.ii II #{149}ii. illii i...II. iI.I.I .I . .11111 tEEIC CACER @CIE1T EIani, .ogIi AMERICAN BOARD OF INTERNAL MEDICINE SCIENTIFIC 1996 Certification Examination in Hematology PROGRAM DI RECTOR Registratioll Period: January 1. 1996 - April 1. 1996 The AmericanCancerSociety is seeking applicants for the position of Scientific Program Director in the Research Exal1ination Date: Grants Department at the National Home Office in Atlanta, November 20, 1996 Georgia. The start date is August 1, 1996.

For I11OFU inlorlilation alid applicatioti I’ortiis. The overall responsibility of this position is to ensure unbi- please contact: ased, rigorous of grant applications by the Society’s Scientific Advisory Committees.The successful candidate will be responsiblefor managing the peer Registration Section review of applications for clinical researchand training American Board of’ Internal Medicine awards. In addition, Scientific Program Directors serve as 3624 Market Street expert sourcesof information on advancesin cancer Philadelphia. PA 19104 research, advise about promising future areas of investi- Telephone: ( 00) 44 I -2246 #{149}( 2 1 5 ) 243- I 500 gation in their specific areas of expertise, and participate Fax: (215) 32-55l5 in collaborative proecIsthroughout the Society.

Applicants must have an MD or equivalent degree plus

AMERICAN ASSOCIATION FOR five years of recent experience as an established investi- CANCER RESEARCH gator on peer reviewed clinical or related oncology researchprojects.The position is largely administrative The American Association for Cancer Research (AACR) is a professional society of over 10,600 and reports to the Vice Presidentfor ResearchGrants. scientists and physicians involved in all aspects of Salary is commensuratewith the candidate’squalifications basic, clinical, and translational cancer research. and experience. Members of the AACR enjoy

. subscriptions to Cancer Research, Cell Growth & The American CancerSociety’sNational ResearchProgram Differentiation (CG&D), Cancer Epidemiology, Biomarkers & Prevention, and Clinical Cancer (Extramural Grants, Intramural Epidemiology and Research at reduced member rates Surveillance Research,and the Behavioral ResearchUnit) . reduced registration rates at the AACR Annual is housed in the National Home Office, in closeproximity Meeting, Special Conferences, and International Meetings to Emory University and the Centersfor DiseaseControl and Prevention. For confidential consideration, please send . Employment Register, Directory of Members, public education activities, and many other letter of interest, curriculum vitae and the names of three benefits referencesby May 1, 1996 to: John J. Stevens, MD, Special programs to provide enhanced career devel- Vice President for Research Grants, American opment opportunities for minority scientists include Cancer Society, 1599 Clifton Rd, N.E., Atlanta, . Session on Career Development at Annual GA 30329-4251 Meeting

. Mentorship Program S Travel Awards to Scientific Meetings American Association for Cancer Research AMERICAN

Public Ledger Building, Suite 816 S., CANCER 150 5. Independence Mall West I Philadelphia, PA 19106-3483 Telephone: (215) 440-9300 EU6O111Y EEL@VC /t/t/ FAX: (215) 440-9313 I E-Mail: [email protected] Priority reading for over 50 years - . State-of-the-art laboratory and cited more than any other journal in clinical investigations

its field . Advances in Brief

CANCER RESEARCH . Selected review articles

. Proceedings of theAmeri can Vol. 56, 1996 (24 issues) Associationfor Cancer Research: ISSN 0008-5472 annual issue ofresearch abstracts Editor-in-Chief Individual nonmembers: $460; Carlo M. Croce, M.D. OutsideU.S.: $550 Institutions: $595*; Outside U.S.: $725* * Includes a subscription to (‘linical Cancer Research. Aable as acombined subsciipon only.

A major resource on the molecular #{149}Original in vitro and in vivo studies biology of cancer ofthe molecular biology of cancer, CELL GROWTH including normal and abnormal & DIFFERENTIATION cellular processes

. Research Capsules Vol. 7, 1996 ( 1 2 issues) #{149}Viewpoints ISSN 1044-9523 Individual nonmembers: $95 Editor-in-Chief Outside U.S.: $135 George E Vande Woude, Ph.D. Institutions: $245; Outside U.S.: $285

An up-to-the-minute journal spanning three vital fields . Original research on causes and prevention of cancer in humans CANCER EPIDEMIOLOGY, , Invited editorials BIOMARKERS & PREVENTION . Selected review articles

Vol. 5, 1996 (12 issues) . Short communications ISSN 1055-9965 . Meeting reports Individual nonmembers: $85 Editor-in-C’hief OutsideU.S.: $125 Pelayo Correa, M.D. Institutions: $2 1 5; Outside U.S.: $255

An exciting new forum for clinical #{149}Research articles and translational cancer research #{149}Advances in Brief CLINICAL CANCER RESEARCH #{149}Minireviews #{149}Controversies in Clinical Vol. 2, 1996 ( 1 2 issues) Cancer Research ISSN 1078-0432 Individual nonmembers: $95 Editor-in-thief Out5ideU.S.: $135 John Mendelsohn, M.D. Institutions: $595*; Outside U.S.: $725* *lncludes a subscription to Cancer Research, Available as a combined subscription only.

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