DOCSLIB.ORG

Front Matter -. Clinical Cancer Research

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Front Matter -. Clinical Cancer Research An Official Journal of the American Association for . Cancer Research Clinical Cancer Research May 1998 #{149}Volume 4 Number 5 PP. 1079-1358 #{149}ISSN 1078-0432 Visit the AACR Website! www.aacr.org Now Online: 1998 Annual Meeting Abstracts Abstracts of AACR Journal Articles Turn to our website to find: AACR scientific meeting schedule Tables of Contents of AACR journals E Instructions for Authors Information about AACR Research Fellowships and Young Investigator Awards The latest AACR newsletter, and more! L 1kCER AMERICAN ASSOCIATION FOR CANCER RESEARCH Iifl ICcJ I An Official Journal American Association cincer Cancer Research ReSecI rch 1kCIR American Association for Editor-in-Chief Cancer Research, Inc. John Mendelsohn Executive Director and Growth factors, hormones, cell growth: Director of Publications Margaret Foti radiation therapy, surgery, subspecialtv investigation Publications St off Deputy Editor Associate Director of Publications Waun Ki Hong Mary Anne Mennite Clinical trials targeted at specific nalignancies, cheinoprevention Manager, Editorial Services Heide M. Pusztay Senior Editors Staff Editors Bruce A. Chabner Paul Sondel Michael J. Bevendge Clinical pharmacology and pharnacokinetics, Immunotherapy and cvtokines-preclinical, and Kathleen C. Assenmacher drug ,netabolic,n, drug sensitivity and resistance, clinical trials Pamela R. Amold drug interactions Ronald M. Vitale Beverly A. Teicher Staff Assistant Michael B. Kastan Experinenial therapeutics, preclinical Mary Ellen Pining Cell cycle regulation, cell death pharmacology, combined modality regimens, Senior Editorial Assistant Theresa A. Griffith Lance A. Liotta ani,nal therapy models Editorial Assistants Pathology, metastasis Jeffrey M. Trent Valerie L. Samuel Genetics, cytogenelics Cecilia Gallo David Sidransky Marketing Coordinator Molecular pathogenesis. molecular correlates Robert B. O’Malley Associate Editors Administrative Staff Martin D. Abeloff Paul F. Engstrom S. B. Kaye William P. Peters Director of Administration Carmen J. Allegra Eric R. Fearon David P. Kelsen Herbert M. Pinedo Adam D. Blistein James 0. Armitage Isaiah J. Fidler David Khayat Philip A. Pizzo Controller Joan D. Ritchie Laurence H. Baker Richard M. Fox John M. Kirkwood William K. Plunkett Manager, Meetings and Exhibits Charles M. Baich Michael A. Friedman Donald W. Kufe Jerome B. Posner Jeffrey M. Ruben Barthel Barlogie Zvi Y. Fuks Steven M. Larson Derek Raghavan Meeting Planner Robert C. Bast, Jr. Stephen L. George John S. Lazo Mark J. Ratain Carole L. Kanoff Cohn B. Begg Giuseppe Giaccone Victor A. Levin John C. Reed Public Information Coordinator Jenny Anne Horst-Martz Joseph R. Bertino Luca Gianni Allen Lichter Ralph A. Reisfeld Assistant to the Executive Director Clara D. Bloomfield Anna Giuhiano Marc E. Lippman Jerome Ritz Ruth E. Fortson Ronald H. Blum Eli Glatstein Edison T. Liu Jack A. Roth Membership Development George J. Bosl David W. Golde Patrick J. Loehrer, Sr. Eric B. Rowinsky Coordinator Paul A. Bunn, Jr. Mark R. Green Dan L. Longo Edward A. Sausville Robin E. Felder Michael T. Lotze Administrative Assistant Michael A. Cahigiuri Jerome E. Groopman Howard I. Scher Margaret A. Pickels Alfred E. Chang William N. Hait Maurie Markman Richard L. Schilsky Systems Specialist Paul B. Chapman Adrian L. Harris William P. McGuire III Richard M. Simon Lydia I. Rodriguez Michaele C. Christian Curtis C. Harris Roland Mertelsmann John F. Smyth Secretary Curt I. Civin Sandra J. Horning Frank L. Meyskens, Jr. Jeffrey A. Sosman Malika L. Wright Ronald Crystal William J. Hoskins John D. Minna Michael B. Sporn Editorial Assistant Diana F. Certo William S. Dalton Janet A. Houghton Monica Morrow Louise C. Strong Office Clerk Albert B. Deisseroth Stephen B. Howell James L. Muishine Masaaki Terada James J. Waters Patricia K. Donahoe Daniel C. Ihde Sharon B. Murphy Daniel D. Von Hoff Data Entry Clerk Ross C. Donehower John T. Isaacs Charles E. Myers Raymond P. Warrell, Jr. Robert A. Simms II Timothy J. Eberlein Robert B. Jenkins Larry Norton Jane Weeks Merrill J. Egorin David H. Johnson Richard J. O’Reilly Ralph R. Weichselbaum Frederick R. Eilber V. Craig Jordan Robert F. Ozols Theresa L. Whiteside AACR Publications Department Robert M. Elashoff Barton A. Kamen Ira Pastan Leonard A. Zwelhing Public Ledger Building. Suite 826 150 South Independence Mall West Editorial Office Philadelphia. PA 19106-3483 Phone: (215) 440-9300 Colleen M. Hubona, Executive Editor, Department of Educational Publishing Services-227, The University of Texas M.D. FAX: (215) 440-9354 Anderson Cancer Center. 1515 Holcombe Boulevard, Houston. Texas 77030. Phone: (713) 792-6014; Fax: (713) 792-6016. Accelerated mailing of all AACR journals to AACR members in Japan is supported by a generous grant from the Banyu Pharmaceutical Company, Tsukuba, Japan. One-year subscriptions to Clinical Cancer Research are made available to third-year hematology/oncoloaj fellows in the United States through the generous support of Rh#{244}ne-Poulenc Rorer Oncology. Clinical Cancer Research is published monthly. one volume per year. by the American Association for Cancer Research. Inc. (AACR). Except for members ofthe AACR. all subscriptions are payable in advance to AACR, Subscription Office. P.O. Box I 1806. Birmingham. AL 35202 Phone: (800) 633-4931 or (205 995-1567: FAX: (205) 995-1588J. to which all business communications. remittances (in United States currency or its equivalent). and subscription orders should he sent. In Japan. send orders and inquiries to (sole agent): USACO Corporation. Tsutsumi Bldg.. 13.12. Shimbashi l.chome. Minato-ku. Tokyo 105. Japan: TeL (03) 502-6471. Individuals who are not AACR members may subscribe to Volume 4 (1998) of Clinical Cancer Research at the rate of $120 U.5J$160 foreign. Clinical Cancer Research is only available to instiwtions as a combined subscription with Cancer Research. The combined 998 institutional subscription price of $795 U.S./5925 foreign includes $210 U.SJ$250 foreign for a subscription to Clinical CancerResearch. (Foreign subscription cost includes cost of surface mail. For faster delivery, expedited mailing rates are available by contacting the AACR Publications Department.) Canadian subscribers should add 7% GST. Changes of address notification should be sent 60 days in advance and include both old and new addresses. Member subscribers should send address changes to: AACR Member Services. Public Ledger Bldg.. Suite 826. 150 South Independence Mall west, Philadelphia. PA 19106-3483. Nonmember subscribers should send changes of address to: AACR Subscription Office, P.O. Box I 1806, Binningham. AL 35202. Copies of the journal which are undeliverable because of address changes will be destroyed. IUIIIIIIllIUlli1111111UIIUIIIIIIIIIIII NSNA-Z1Y-8X2Y 1i w Notice to Members of the American Association for Cancer Research (AACR) Officers for 1998 -1999 President: Webster K. Cavenee, Ludwig Institute for Cancer Research, La Jolla, CA 92093-0660 President-Elect: Daniel D. Von Hoff, Institute for Drug Development, San Antonio, TX 78245 Treasurer: Bayard D. Clarkson, Memorial Sloan-Kettering Cancer Center, New York, NY 10021 Executive Director: Margaret Foti, AACR, Public Ledger Bldg., Suite 826, Philadelphia, PA 19106-3483 Annual Dues The annual dues of active members of the AACR are $175, $50 of which may be applied to a subscription to Clinical Cancer Research. Corresponding members of the Association will be charged an appropriate fee to offset periodicals postage costs. Payment of dues and changes of address of members of the Association should be sent promptly to Margaret Foti, Executive Director, AACR, Public Ledger Bldg., Suite 826, 150 South Independence Mall West, Philadelphia, PA 19106-3483; Phone: (215) 440-9300; FAX: (215) 440-9313. Submission of Manuscripts Cancer Research, Inc., since these articles are considered to be in Clinical Cancer Research, a journal of the American Association the public domain. In the case of articles supported by federal for Cancer Research, publishes original articles describing clinical grants or contracts, copyright transfer to the American Association research on the cellular and molecular characterization, prevention, for Cancer Research, Inc., is required. The federal government diagnosis, and therapy of human cancer. Its focus is on innovative may retain a nonexclusive license to publish or republish such clinical research and translational research which bridges the labo- material. ratory and the clinic. Clinical Cancer Research is especially inter- The Journal will routinely allow authors (or others with the ested in clinical trials evaluating new treatments for cancer; research permission of the authors) to include select parts of a copy- on molecular abnormalities that predict incidence, response to ther- righted article in reviews, books, or subsequent papers, upon apy, and outcome; and laboratory studies of new drugs and biolog- written request to the AACR Director of Publications. Requests ical agents that will lead to clinical trials in patients. All submissions to reproduce an article in its entirety will be considered on an undergo peer review. Papers should be sent directly to an appropri- individual basis and permission may be granted contingent upon ate Senior Editor or to the Editor-in-Chief for review. See “Instruc- payment ofan appropriate copyright fee. All reproduction requests tions for Authors” (page ii of this issue) for complete mailing must include a brief description of intended use and a stamped,
Load more

Recommended publications
  • Front Matter
    ANTICANCER RESEARCH International Journal of Cancer Research and Treatment ISSN: 0250-7005 Volume 36, Number 1, January 2016 Contents Reviews Using Epigenetic Therapy to Overcome Chemotherapy Resistance. J. STRAUSS, W.D. FIGG (Bethesda, MD, USA) ..................................................................................................................................... 1 Potential of Amifostine for Chemoradiotherapy and Radiotherapy-associated Toxicity Reduction in Advanced NSCLC: A Meta-Analysis. A. DEVINE, L. MARIGNOL (Dublin, Ireland) .......................................... 5 Factors Affecting Survival in Patients with Lung Metastases from Colorectal Cancer. A Short Meta-analysis. F. LUMACHI, G.B. CHIARA, R. TOZZOLI, A. DEL CONTEA, S.M.M. BASSO (Padova; Pordenone, Italy)..... 13 TAS-102 an Emerging Oral Fluoropyrimidine. J. CHEN, M. HAN, M.W. SAIF (St. Lucia; Wollongong, Australia; Boston, MA, USA)........................................................................................................... 21 Experimental Studies Inhibition of Chronic Pancreatitis and Murine Pancreatic Intraepithelial Neoplasia by a Dual Inhibitor of c- RAF and Soluble Epoxide Hydrolase in LSL-KrasG12D/Pdx-1-Cre Mice. J. LIAO, S.H. HWANG, H. LI, J.- Y. LIU, B.D. HAMMOCK, G.-Y. YANG (Chicago, IL; Davis, CA, USA)............................................. 27 HUHS1015 Suppresses Colonic Cancer Growth by Inducing Necrosis and Apoptosis in Association with Mitochondrial Damage. Y. KAKU, A. TSUCHIYA, T. SHIMIZU, A. TANAKA, T. NISHIZAKI (Nishinomiya;
    [Show full text]
  • The Future of Cancer Research: ACCELERATING SCIENTIFIC INNOVATION
    The Future Of Cancer Research: ACCELERATING SCIENTIFIC INNOVATION President’s Cancer Panel Annual Report 2010-2011 U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute The President’s Cancer Panel LaSalle D. Leffall, Jr., M.D., F.A.C.S., Chair (through 12/31/11) Charles R. Drew Professor of Surgery Howard University College of Medicine Washington, DC 20059 Margaret L. Kripke, Ph.D. (through 12/31/11) Vivian L. Smith Chair and This report is submitted to the President of the United States Professor Emerita in fulfillment of the obligations of the President’s Cancer Panel The University of Texas to appraise the National Cancer Program as established in MD Anderson Cancer Center accordance with the National Cancer Act of 1971 (P.L. 92-218), Houston, TX 77030 the Health Research Extension Act of 1987 (P.L. 99-158), the National Institutes of Health Revitalization Act of 1993 (P.L. 103-43), and Title V, Part A, Public Health Service Act (42 U.S.C. 281 et seq.). Printed November 2012 For further information on the President’s Cancer Panel or additional copies of this report, please contact: Abby B. Sandler, Ph.D. Executive Secretary President’s Cancer Panel 9000 Rockville Pike Bld. 31/Rm B2B37 MSC 2590 Bethesda, MD 20892 301-451-9399 [email protected] http://pcp.cancer.gov The Future Of Cancer Research:: ACCELERATING SCIENTIFIC INNOVATION President’s Cancer Panel Annual Report 2010-2011 Suzanne H. Reuben Erin L. Milliken Lisa J. Paradis for The President’s Cancer Panel November 2012 U.S.
    [Show full text]
  • Instructions for Authors
    [CANCER RESEARCH 49. 257-262. January I. 1989] INSTRUCTIONS FOR AUTHORS Cancer Research is the official journal of the American Association Since editorial staff time to answer telephone calls from authors is for Cancer Research, Inc., and is devoted to the publication of significant, limited, inquiries regarding the status of manuscripts should, if possible, original research in all the subfields of cancer research, including: bio be submitted in writing and should be made only on those manuscripts chemistry; biology; biophysics; chemical and physical carcinogenesis, that exceed the average review time. and mutagenesis; clinical investigations; endocrinology; epidemiology; The Editorial Office cannot accept collect telephone callsfrom authors. experimental pathology; immunology; molecular biology and genetics; physiology; preclinical pharmacology and experimental therapeutics (in SUBMISSION AND PUBLICATION FEES cluding biological therapy); radiobiology and radiotherapy; and virology. A manuscript processing fee of $75 is assessed for each manuscript to Clinical investigations and epidemiológica! studies are published in a help defray the cost of editorial review. A check (drawn on a U.S. bank) separate section from papers in the basic sciences. or purchase order in U.S. currency, payable to the American Association Only those papers that report results of novel and timely studies and for Cancer Research, Inc., must accompany the manuscript. If a purchase that meet high standards of scientific quality will be accepted. Papers are order must precede payment by an institution, it is the author's respon subjected to stringent review and are published within about three sibility to ensure that the purchase order is followed by payment of the months of acceptance.
    [Show full text]
  • Call for Abstracts
    CALL FOR ABSTRACTS ★ Abstract Submission Deadline: November 19, 2020 ★ Late-Breaking and Clinical Trials APRIL 9-14, 2021 Abstract Submission Deadline: January 11, 2021 Continuing Medical Education Activity - AMA PRA Category 1 Credits™ available DISCOVERY SCIENCE DRIVING AACR.ORG ★ #AACR21 CLINICAL BREAKTHROUGHS TABLE OF CONTENTS 2 Key Dates 3 Welcome 4 Scientific Program APRIL 9-14, 2021 Plenary Sessions Major Symposia Advances Sessions Forums Educational Program DISCOVERY 8 Policy Sessions SCIENCE 9 Spotlight on Clinical Trials DRIVING CLINICAL 10 Professional Advancement Opportunities BREAKTHROUGHS 11 Continuing Medical Education (CME) 12 Survivor and Patient AACR OFFICERS Advocacy Program President 13 Press Coverage and Social Media Antoni Ribas President-Elect 14 Financial Support for Attendance David A. Tuveson Treasurer 16 Guidelines for Preparation and William N. Hait Submission of Abstracts Immediate Past President Elaine R. Mardis 19 Abstract Categories Chief Executive Officer Margaret Foti 24 AACR Membership Opportunities Board of Directors 26 General Information Adriana Albini Scott A. Armstrong 28 Annual Meeting Committees René Bernards Marcia R. Cruz-Correa Keith T. Flaherty Silvia Chiara Formenti Elaine Fuchs ABOUT THE COVER IMAGE: Roy S. Herbst Carl H. June ©2020 American Association for Cancer Research Karen E. Knudsen Inside of sphere (clockwise): AACR Virtual Special Conference: Edison T. Liu Epigenetics and Metabolism art; Glioblastoma (iStock); DNA sequencing (Getty) Ira Mellman Foreground of sphere (clockwise): 3D
    [Show full text]
  • Instructions for Authors
    ICANCER RESEARCH 55, 202-208. January I. 1995] INSTRUCTIONS FOR AUTHORS Cancer Research, the official journal of the American Association for than an abstract or preliminary communication, has been or will be submitted Cancer Research, Inc. (AACR). is devoted to the publication of significant, to or published in any other primary scientific journal. original studies in all areas of basic, clinical, translational or epidemiological It is also understood that all authors listed on a manuscript have agreed to its cancer research. Topics include biochemistry; biophysics; chemical, physical, submission and content. For revised manuscripts, if an author is deleted or a and viral carcinogenesis and mutagenesis; clinical investigations including new author is added, it is the responsibility of the corresponding author to clinical trials; endocrinology; epidemiology and prevention; experimental pa provide the Publications Department with written documentation at the time of thology; experimental therapeutics; immunology and immunotherapy includ resubmission that the authors involved are aware of and agree to the changes ing biological therapy; molecular biology and genetics; physiology; radiobi- in authorship. Cancer Research accepts no responsibility for such changes. ology and radiation oncology; tumor biology; and virology. The Journal maintains an international editorial board of Associate Editors Only those papers reporting results of novel, timely, and significant research with broad expertise in all areas of cancer research. These Associate Editors, and meeting high standards of scientific merit will be accepted. Papers are along with a large group of external reviewers, provide fair and thorough stringently reviewed and regular research articles are published within an evaluations of papers submitted to Cancer Research.
    [Show full text]
  • American Association for Cancer Research Official Membership
    American Association for Cancer Research Official Membership Transfer Form 615 Chestnut Street | 17th Floor | Philadelphia, PA 19106-4404 | 215-440-9300 Telephone | 866-423-3965 Toll Free | 267-765-1078 Fax | [email protected] Section 1: Candidate Information (Please type or print clearly) Last/Family Name: ___________________________________________ First Name: __________________________________ Middle Initial: ______________________________________ Date of Birth (mm/dd/year): __________________________ Title and Dept.: __________________________________________________________________________________________ Institute/Company: _______________________________________________________________________________________________________________________________________ Division: _______________________________________________________________________________________________________________________________________________ Academic Degrees Indicate highest degree earned, year earned, and institution granting the degree. (Indicate multiple degrees as appropriate, i.e., MD, PhD) q Doctoral (MD, PhD, etc.) ________________________________________________________________________________________________________________________________ q Master (MS, MA, etc.) ________________________________________________________________________________________________________________________________ q Bachelor (BA, BS, etc.) ________________________________________________________________________________________________________________________________ q Associate
    [Show full text]
  • The Journal of Cancer Research
    A HISTORY OF THE JOURNAL CANCER RESEARCH Commemorating the Journal’s 75th Anniversary February 15, 2016 Volume 76 Number 4 Cancer Research 75TH ANNIVERSARY Driving Innovation to Prevent and Cure Cancer 615 Chestnut Street, 17th Floor Philadelphia, PA 19106 215-440-9300 \\ AACRJournals.org www.AACRJournals.org The following history of the journal Cancer Research and its predecessors was written by June Eberharter, production editor for the Archives staff in the AACR Executive Office. June Eberharter died two months before this history was published. She had been managing editor for two AACR journals, Clinical Cancer Research and Molecular Cancer Research, and previously worked at most of the major publishing houses in the Philadelphia area — a mentor and teacher to a generation of editors. In her 13 years at the AACR, she applied her considerable editorial skills toward conquering the disease that ultimately took her life. This publication is dedicated to June. Kathleen Case, AACR Archivist 5 | AACR: THE FOUNDING 6 | THE JOURNAL OF CANCER RESEARCH 7 | THE AMERICAN JOURNAL OF CANCER 8 | CANCER RESEARCH, THE NEW JOURNAL • The Post-World War II Years 9 | THE JOURNAL RESTRUCTURED: 1950-1959 10 | THE JOURNAL MATURES: 1960-1969 • Smoking and Cancer 11 | AACR LEADER PROFILE: HUGH J. CREECH, PHD 12 | DOCUMENTING THE WAR ON CANCER: 1970-1979 13 | A DECADE OF INNOVATION: 1980-1989 14 | AACR LEADER PROFILE: MARGARET FOTI, PHD, MD (HC) 14 | ANTICIPATING THE NEW MILLENIUM: 1990-1999 16 | A NEW CENTURY OF DISCOVERY: 2000-2009 17 | CURRENT INITIATIVES: 2010 AND BEYOND 18 | APPENDIX 1. JOURNAL STATISTICS AND RANKINGS • Journal Citation Reports • The Eigenfactor® • The H-Index and SCImago Journal Rank (SJR) TABLE OF CONTENTS 20 | REFERENCES 4 History of Cancer Research AACR: THE FOUNDING Gaslights illuminated the streets of Washington on the evening of May 7, 1907, when a group of seven scientists with a mission met at the new Willard Hotel.
    [Show full text]
  • 2021 Aacr Publications Media Kit
    2021 AACR PUBLICATIONS MEDIA KIT AACRJournals.org TRUSTED AND TIMELY PUBLICATION OF SCIENTIFIC DISCOVERIES Founded in 1907, the American Association for Cancer Research (AACR) is the first and largest scientific organization in the world focused on every aspect of high-quality, innovative cancer research. For over a century, our mission has always been to prevent and cure cancer through research, education, communication, and collaboration. The AACR currently publishes nine peer-reviewed journals that cover the full spectrum of cancer research. In 2020, we added Blood Cancer Discovery, broadening our highly esteemed portfolio’s scope to include all research on hematologic malignancies. The AACR Journals’ reputation for scientific breadth and excellence continues to attract the premier researchers in the field. We are proud to note that four of the AACR journals rank in the top 25 of all oncology journals in terms of Impact Factor, and while AACR publishes around 4.5% of the articles in the Oncology category, our journals garnered 14% of all citations in the field in 2019, according to Clarivate Analytics’ 2019 Journal Citation Reports® (Clarivate Analytics 2020). Cancer Discovery received an Impact Factor of 29.497 and ranks 6th overall in the Oncology category, while Clinical Cancer Research, Cancer Research, and Cancer Immunology Research rank 17th, 19th, and 23rd out of 244 journals in the Oncology category, respectively. For More Information: Maura Paoletti National Sales Manager The Walchli Tauber Group 443-512-8899 ext. 110 [email protected] AACRJournals.org CANCER RESEARCH The Foundational Cancer Journal Driving Transformative Science Commitment and Issue Date Material Deadline 1/1/21 11/25 As one of the most frequently cited and well-respected 1/15/21 12/13 cancer journals in the world, Cancer Research publishes 2/1/21 1/2 original studies, reviews, and opinion pieces offering 2/15/21 1/15 significance and broad impact to a diverse audience spanning basic, preclinical, clinical, prevention, and 3/1/21 2/1 epidemiologic research.
    [Show full text]
  • Clinical Oncology AACR Workshop on Methods in Clinical Cancer
    Vol. 2, 611, March 1996 Clinical Cancer Research 611 Annual Meeting fee. (If additional funding is received, some The AACR’s Annual Meeting is one of the larg- AACR travel support may be available for junior fac- est and most important annual gatherings of sci- The American Association for Cancer Re- ulty.) entists engaged in cancer research worldwide. search (AACR) was founded in 1907 to bring The Workshop Organizing Committee is The next Annual Meeting will take place in together active investigators of the cancer chaired by Drs. Daniel D. Von Hoff(for AACR) Washington, D. C., from April 20-24, l996. The problem for the presentation and discussion of and Charles A. Coltman, Jr. (for ASCO), both of the Cancer Therapy and Research Center in Chairperson ofthe Annual Meeting is Lorraine J. new findings and to foster advances in cancer San Antonio, Texas. They will invite and se- Gudas of the Cornell University Medical Col- research. Today the Association has more than 10,000 members working in all of the subdis- lect a distinguished faculty that will deliver lege. Dr. Gudas and her Program Committee ciplines of cancer research in the United over 20 hours of lectures on a variety of topics have invited outstanding scientists in the field to States, Canada, and more than 50 other coun- in the field and direct four 2-hour small group organize plenary sessions, symposia, methods tries. Information on AACR programs and ac- discussion sessions in which 25-30 partici- workshops, controversy sessions, and meet-the- tivities can be obtained from pants will obtain practical training in subjects expert sunrise sessions.
    [Show full text]
  • A Survey on Data Reproducibility and the Effect of Publication Process on the Ethical Reporting of Laboratory Research Delphine R
    Published OnlineFirst April 11, 2018; DOI: 10.1158/1078-0432.CCR-18-0227 Cancer Therapy: Preclinical Clinical Cancer Research A Survey on Data Reproducibility and the Effect of Publication Process on the Ethical Reporting of Laboratory Research Delphine R. Boulbes1, Tracy Costello2, Keith Baggerly3, Fan Fan1, Rui Wang1, Rajat Bhattacharya1, Xiangcang Ye1, and Lee M. Ellis1,4 Abstract Purpose: The successful translation of laboratory research into Results: Responses to questions related to mentoring and effective therapies is dependent upon the validity of peer-reviewed training practices were largely positive, although an average of publications. However, several publications in recent years approximately 25% did not seem to receive optimal mentoring. A suggested that published scientific findings could be reproduced total of 39.2% revealed having been pressured by a principle only 11% to 45% of the time. Multiple surveys attempted to investigator or collaborator to produce "positive" data. About elucidate the fundamental causes of data irreproducibility and 62.8% admitted that the pressure to publish influences the way underscored potential solutions, more robust experimental they report data. The majority of respondents did not believe that designs, better statistics, and better mentorship. However, no extensive revisions significantly improved the manuscript while prior survey has addressed the role of the review and publication adding to the cost and time invested. process on honest reporting. Conclusions: This survey indicates that trainees believe that Experimental Design: We developed an anonymous online the pressure to publish affects honest reporting, mostly ema- survey intended for trainees involved in bench research. The nating from our system of rewards and advancement.
    [Show full text]
  • American Association for Cancer Research Official Membership Application Form
    American Association for Cancer Research Official Membership Application Form 615 Chestnut Street | 17th Floor | Philadelphia, PA 19106-4404 | 215-440-9300 Telephone | 866-423-3965 Toll Free | 267-765-1078 Fax | [email protected] Section 1: Application Information Check one of the following boxes if this application is being submitted between September 1 and December 31. (If dues are applied to the forthcoming year, the membership will take effect on January 1, but the candidate will not be eligible to sponsor an abstract for presentation at the Annual Meeting in March or April of that year.) The enclosed payment should be applied to the q Current Year q Forthcoming Year (ineligible to sponsor an abstract for upcoming Annual Meeting) Section 2: Candidate Information (Please type or print clearly) Last/Family Name: _______________________________________ First Name: _______________________________ Middle Initial: ___________________________________ Date of Birth (mm/dd/year): _______________________ Title and Dept.: ____________________________________________________________________________________ Institute/Company: _______________________________________________________________________________________________________________________________ Division: ______________________________________________________________________________________________________________________________________ Academic Degrees Indicate highest degree earned, year earned, and institution granting the degree. (Indicate multiple degrees as appropriate, i.e., MD,
    [Show full text]
  • Front Matter
    ANTICANCER RESEARCH International Journal of Cancer Research and Treatment ISSN: 0250-7005 Volume 37, Number 1, January 2017 Contents Reviews Clinical Implications of High-mobility Group Box-1 (HMGB1) and the Receptor for Advanced Glycation End-products (RAGE) in Cutaneous Malignancy: A Systematic Review. A.H. NGUYEN, S.Q. DETTY, D.K. AGRAWAL (Omaha, NE, USA) ............................................................................................................................. 1 Parenchymal-sparing Hepatectomy as the New Doctrine in the Treatment of Liver-metastatic Colorectal Disease: Beyond Oncological Outcomes. D. MORIS, D. DIMITROULIS, S. VERNADAKIS, A. PAPALAMPROS, E. SPARTALIS, A. PETROU, T.M. PAWLIK, E. FELEKOURAS (Cleveland; Columbus, OH, USA; Athens, Greece) ............................................................................................................................................................................ 9 Three Pathways of Colonic Carcinogenesis in Rats. C.A. RUBIO (Stockholm, Sweden) .................................. 15 Advances in Experimental Targeted Therapy and Immunotherapy for Patients with Glioblastoma Multiforme. J. POLIVKA JR, J. POLIVKA, L. HOLUBEC, T. KUBIKOVA, V. PRIBAN, O. HES, K. PIVOVARCIKOVA, I. TRESKOVA (Plzen, Czech Republic) ...................................................................................................................... 21 Histone Deacetylase Inhibitors: An Attractive Therapeutic Strategy Against Breast Cancer. C. DAMASKOS, S. VALSAMI, M. KONTOS, E. SPARTALIS,
    [Show full text]