2021 AACR PUBLICATIONS MEDIA KIT

AACRJournals.org TRUSTED AND TIMELY PUBLICATION OF SCIENTIFIC DISCOVERIES

Founded in 1907, the American Association for Cancer Research (AACR) is the first and largest scientific organization in the world focused on every aspect of high-quality, innovative cancer research. For over a century, our mission has always been to prevent and cure cancer through research, education, communication, and collaboration.

The AACR currently publishes nine peer-reviewed journals that cover the full spectrum of cancer research. In 2020, we added Blood Cancer Discovery, broadening our highly esteemed portfolio’s scope to include all research on hematologic malignancies.

The AACR Journals’ reputation for scientific breadth and excellence continues to attract the premier researchers in the field. We are proud to note that four of the AACR journals rank in the top 25 of all oncology journals in terms of , and while AACR publishes around 4.5% of the articles in the Oncology category, our journals garnered 14% of all citations in the field in 2019, according to Clarivate Analytics’ 2019 Journal Citation Reports® (Clarivate Analytics 2020). Cancer Discovery received an Impact Factor of 29.497 and ranks 6th overall in the Oncology category, while Clinical Cancer Research, Cancer Research, and Cancer Research rank 17th, 19th, and 23rd out of 244 journals in the Oncology category, respectively.

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Maura Paoletti National Sales Manager The Walchli Tauber Group 443-512-8899 ext. 110 [email protected]

AACRJournals.org CANCER RESEARCH The Foundational Cancer Journal Driving Transformative Science

Commitment and Issue Date Material Deadline 1/1/21 11/25 As one of the most frequently cited and well-respected 1/15/21 12/13 cancer journals in the world, Cancer Research publishes 2/1/21 1/2 original studies, reviews, and opinion pieces offering 2/15/21 1/15 significance and broad impact to a diverse audience spanning basic, preclinical, clinical, prevention, and 3/1/21 2/1 epidemiologic research. Cancer Research seeks manuscripts 3/15/21 2/11 that offer pathobiological and translational impact to 4/1/21* 3/4 inform the personal, clinical, and societal problems posed 4/15/21 3/14 by cancer. The main scope of the Journal is captured in its 5/1/21 4/3 primary subsections, which focus on molecular and cellular 5/15/21 4/15 pathobiology, tumor and stem , therapeutics and 6/1/21 5/7 targets, microenvironment and immunology, prevention and epidemiology, and integrated systems and technology. 6/15/21 5/15 7/1/21 6/4 Impact Factor: 9.727 (2019) 7/15/21 6/17 Frequency: Semi-monthly print issues 8/1/21 7/7 8/15/21 7/15 First Published: 1941 9/1/21 8/1 Peer Reviewed: Yes 9/15/21 8/15 10/1/21 9/4 Editor-in-Chief: Chi Van Dang, MD, PhD, 10/15/21 9/16 Ludwig Institute for Cancer Research (New York, NY) 11/1/21 10/2 11/15/21 10/15 12/1/21 11/1 12/15/21 11/14 *Annual Meeting Issue Cancer Research Rates

Print Advertising Digital Advertising Frequency 1x Multiple Website Statistics ETOCs Full Page $1,885 $1,710 96,000 users/month 12,000 recipients/2X per month 1/2 Page $1,200 $1,100 710,000 page views/month $1,800 net per deployment 1/4 Page $875 $775 140,000 sessions/month Discount offered with multiple deployments 4-Color Rates: $700 Banner Ads (in addition to B/W rates) 310,000 US impressions/month Global $45.00 CPM Premium Opportunities: USA Only $50.00 CPM C2: +25% C3: +10% C4: +50% Guaranteed Position: +15% cancerres.AACRJournals.org CLINICAL CANCER RESEARCH The Journal of Clinical and Translational Research

Commitment and Issue Date Material Deadline 1/1/21 12/5 Clinical Cancer Research focuses on innovative clinical 1/15/21 12/18 and translational cancer research studies that bridge the laboratory and the clinic. The Journal is especially interested 2/1/21 1/2 in clinical trials evaluating new treatments, accompanied 2/15/21 1/15 by research on and molecular alterations or 3/1/21 1/31 biomarkers that predict response or resistance to treatment. 3/15/21 2/10 The Journal also prioritizes laboratory and animal studies 4/1/21* 2/27 of new drugs and molecule-targeted agents with the 4/15/21 3/10 potential to lead to clinical trials and studies of targetable 5/1/21 3/25 mechanisms of oncogenesis, progression of the malignant phenotype, and metastatic disease. 5/15/21 4/9 6/1/21 4/24 Impact Factor: 10.107 (2019) 6/15/21 5/5 Frequency: Semi-monthly print issues 7/1/21 5/29 7/15/21 6/13 First Published: 1995 8/1/21 6/28 Peer Reviewed: Yes 8/15/21 7/14 9/1/21 7/29 Editor-in-Chief: Keith T. Flaherty, MD, Henri and Belinda 9/15/21 8/15 Termeer Center for Targeted Therapies, Massachusetts General Hospital Cancer Center (Boston, MA) 10/1/21 8/30 10/15/21 9/15 11/1/21 9/30 11/15/21 10/14 12/1/21 10/30 12/15/21 11/14 *Annual Meeting Issue Clinical Cancer Research Rates

Print Advertising Digital Advertising Frequency 1x Multiple Website Statistics ETOCs Full Page $1,125 $1,025 31,000 users/month 9,500 recipients/2X per month 1/2 Page $750 $650 505,000 page views/month $1,800 net per deployment 1/4 Page $525 $425 104,000 sessions/month Discount offered with multiple deployments 4-Color Rates: $700 Banner Ads (in addition to B/W rates) 222,000 US impressions/month Global $45.00 CPM Premium Opportunities: USA Only $50.00 CPM C2: +25% C3: +10% C4: +50% Guaranteed Position: +15% clincancerres.AACRJournals.org CANCER DISCOVERY The Essential Information Source to Serve the Diverse Professional Community in Cancer Science and Medicine

Commitment and Issue Date Material Deadline 1/1/21 12/5 Cancer Discovery publishes paradigm-changing, 2/1/21 1/2 peer-reviewed articles describing major advances in research and clinical trials. Cancer Discovery also publishes 3/1/21 2/1 review articles, perspectives and commentaries, news, and 4/1/21* 3/6 Research Watch summaries of important journal articles. 5/1/21 4/3 Topics span the spectrum of cancer research and medicine, 6/1/21 5/1 from the laboratory to the clinic to epidemiologic studies. 7/1/21 6/2

Impact Factor: 29.497 (2019) 8/1/21 7/1 9/1/21 8/1 Monthly print issues Frequency: 10/1/21 8/29 First Published: 2011 11/1/21 9/30 12/1/21 10/30 Peer Reviewed: Yes *Annual Meeting and Editors-in-Chief: Lewis C. Cantley, PhD, Weill Cornell Medical 10th Anniversary Issue - Rates Vary College and NewYork-Presbyterian Hospital (New York, NY) Greatest Hits issue planned for Luis A. Diaz, MD, Memorial Sloan Kettering Cancer Center Fall 2021 release. - Please (New York, NY) inquire for rates.

Cancer Discovery Rates

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Frequency 1x Multiple Website Statistics ETOCs Full Page $1,125 $1,025 36,000 users/month 15,200 recipients per month 1/2 Page $750 $650 227,000 page views/month $1,800 net per deployment 1/4 Page $525 $425 52,000 sessions/month Discount offered with multiple deployments 4-Color Rates: $700 Banner Ads (in addition to B/W rates) 128,000 US impressions/month Global $45.00 CPM Premium Opportunities: USA Only $50.00 CPM C2: +25% C3: +10% C4: +50% Guaranteed Position: +15%

10th Anniversary Issues - please contact [email protected] for rates cancerdiscovery.AACRJournals.org MOLECULAR CANCER THERAPEUTICS The Journal of Cancer Drug Discovery and Preclinical Development

Commitment and Issue Date Material Deadline 1/1/21 12/4 Molecular Cancer Therapeutics focuses on basic research 2/1/21 1/8 that has implications for cancer therapeutics in the following areas: experimental cancer therapeutics, 3/1/21 2/5 identification of molecular targets, targets for 4/1/21* 3/3 chemoprevention, new models, cancer chemistry and 5/1/21 4/1 drug discovery, molecular and cellular pharmacology, 6/1/21 5/1 molecular classification of tumors, and bioinformatics and 7/1/21 6/4 computational molecular biology. 8/1/21 7/1 Impact Factor: 5.615 (2019) 9/1/21 8/2 10/1/21 9/7 Frequency: Monthly print issues 11/1/21 10/3 First Published: 2001 12/1/21 11/1 *Annual Meeting Issue Peer Reviewed: Yes

Editor-in-Chief: Beverly A. Teicher, PhD (Rockville, MD)

Molecular Cancer Therapeutics Rates

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Frequency 1x Multiple Website Statistics ETOCs Full Page $855 $755 22,000 users/month 6,100 recipients per month 1/2 Page $585 $485 130,000 page views/month $1,800 net per deployment 1/4 Page $450 $350 30,000 sessions/month Discount offered with multiple deployments 4-Color Rates: $700 Banner Ads (in addition to B/W rates) 60,000 US impressions/month Global $45.00 CPM Premium Opportunities: USA Only $50.00 CPM C2: +25% C3: +10% C4: +50% Guaranteed Position: +15% mct.AACRJournals.org CANCER EPIDEMIOLOGY, BIOMARKERS & PREVENTION Translating Science to Populations

Commitment and Cancer Epidemiology, Biomarkers & Prevention publishes original Issue Date Material Deadline peer-reviewed, population-based research on cancer etiology, 1/1/21 12/9 prevention, surveillance, and survivorship. The following topics are of 2/1/21 1/9 special interest: descriptive, analytical, and molecular epidemiology; 3/1/21 2/7 biomarkers, including assay development, validation, and application; 4/1/21* 3/7 chemoprevention and other types of prevention research in 5/1/21 4/3 the context of descriptive and observational studies; the role of behavioral factors in cancer etiology and prevention; survivorship 6/1/21 5/1 studies; and risk factors and the science of cancer health disparities. 7/1/21 6/2 Besides welcoming manuscripts that address individual subjects in 8/1/21 7/1 any of the relevant disciplines, the Editors of Cancer Epidemiology, 9/1/21 8/1 Biomarkers & Prevention encourage the submission of manuscripts 10/1/21 9/5 with a transdisciplinary approach. 11/1/21 10/2 Impact Factor: 4.344 (2019) 12/1/21 10/31 *Annual Meeting Issue Frequency: Monthly print issues

First Published: 1991

Peer Reviewed: Yes

Editor-in-Chief: Elizabeth A. Platz, ScD, MPH, Johns Hopkins Bloomberg School of Public Health (Baltimore, MD)

Cancer Epidemiology, Biomarkers & Prevention Rates

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Frequency 1x Multiple Website Statistics ETOCs Full Page $855 $755 31,000 users/month 6,500 recipients per month 1/2 Page $585 $485 135,000 page views/month $1,800 net per deployment 1/4 Page $450 $350 37,000 sessions/month Discount offered with multiple deployments 4-Color Rates: $700 Banner Ads (in addition to B/W rates) 61,000 US impressions/month Global $45.00 CPM Premium Opportunities: USA Only $50.00 CPM C2: +25% C3: +10% C4: +50% Guaranteed Position: +15% cebp.AACRJournals.org CANCER IMMUNOLOGY RESEARCH Illuminating the Interplay of Cancer and the Immune System

Commitment and Cancer Immunology Research publishes outstanding original Issue Date Material Deadline articles reporting major advances in cancer immunology 1/1/21 12/4 that span the discipline from basic investigations in host- 2/1/21 1/8 tumor interactions to developmental therapeutics in model 3/1/21 2/3 systems, early translational studies in patients, and late- stage clinical trials. The Journal disseminates knowledge of 4/1/21* 3/7 immunology to the cancer research community, catalyzing 5/1/21 4/8 cross-disciplinary work that yields a deeper understanding of 6/1/21 5/5 the host-tumor relationship, more potent cancer treatments, 7/1/21 6/5 and improved clinical outcomes. Specific topics of interest 8/1/21 7/10 include endogenous antitumor immunity, tumor-promoting 9/1/21 8/4 inflammation, cancer antigens, vaccines, antibodies, cellular 10/1/21 9/4 therapy, cytokines, immune regulation, immune suppression, immunomodulatory effects of cancer treatment, emerging 11/1/21 10/6 technologies, and clinical investigations. 12/1/21 11/5 *Annual Meeting Issue Impact Factor: 8.728 (2019)

Frequency: Monthly print issues

First Published: 2013

Peer Reviewed: Yes

Editors-in-Chief: Robert D. Schreiber, PhD, Washington University (St. Louis, MO) and Philip D. Greenberg, MD, PhD, Fred Hutchinson Cancer Research Center (Seattle, WA)

Cancer Immunology Research Rates

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Frequency 1x Multiple Website Statistics ETOCs Full Page $1,060 $960 15,000 users/month 2,200 recipients per month 1/2 Page $725 $625 83,000 page views/month $1,800 net per deployment 1/4 Page $505 $405 20,000 sessions/month Discount offered with multiple deployments 4-Color Rates: $700 Banner Ads (in addition to B/W rates) 38,000 US impressions/month Global $45.00 CPM Premium Opportunities: USA Only $50.00 CPM C2: +25% C3: +10% C4: +50% Guaranteed Position: +15% cancerimmunolres.AACRJournals.org CANCER PREVENTION RESEARCH The Forefront of Prevention Science

Commitment and Issue Date Material Deadline 1/1/21 12/10 Cancer Prevention Research publishes important original 2/1/21 1/9 studies, reviews, and perspectives within the major topic areas of biology of premalignancy; risk factors and risk 3/1/21 2/5 assessment; early detection research; immunoprevention; 4/1/21* 3/4 and chemopreventive and other interventions, including 5/1/21 4/1 the basic science behind them. Cancer Prevention Research 6/1/21 5/1 comprises preclinical, clinical, and translational research, 7/1/21 6/4 with special attention given to molecular discoveries and 8/1/21 7/1 an emphasis on building a translational bridge between the 9/1/21 8/1 basic and clinical sciences. 10/1/21 9/5 Impact Factor: 3.473 (2019) 11/1/21 9/30

Frequency: Monthly print issues 12/1/21 11/4 *Annual Meeting Issue First Published: 2008

Peer Reviewed: Yes

Editors-in-Chief: Raymond N. DuBois, MD, PhD, Medical University of South Carolina (Charleston, SC) and Michael N. Pollak, MD, McGill University (Montreal, QC)

Cancer Prevention Research Rates

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Frequency 1x Multiple Website Statistics ETOCs Full Page $855 $755 11,000 users/month 5,200 recipients per month 1/2 Page $585 $485 40,000 page views/month $1,800 net per deployment 1/4 Page $450 $350 12,000 sessions/month Discount offered with multiple deployments 4-Color Rates: $700 Banner Ads (in addition to B/W rates) 19,500 US impressions/month Global $45.00 CPM Premium Opportunities: USA Only $50.00 CPM C2: +25% C3: +10% C4: +50% Guaranteed Position: +15% cancerpreventionresearch.AACRJournals.org MOLECULAR CANCER RESEARCH Defining the Molecular Basis of Malignancy and Progression

Commitment and Issue Date Material Deadline 1/1/21 12/3 Molecular Cancer Research publishes articles describing 2/1/21 1/8 novel basic cancer research discoveries of broad interest to the field. Areas of emphasis include all cancer-associated 3/1/21 2/4 pathways (including cell-cycle regulation; cell death; 4/1/21* 3/5 chromatin regulation; DNA damage and repair; gene 5/1/21 4/4 and RNA regulation; genomics; oncogenes and tumor 6/1/21 5/6 suppressors; and signal transduction), in addition to studies 7/1/21 6/9 describing new molecular mechanisms and interactions that 8/1/21 7/9 support cancer phenotypes. 9/1/21 8/7 Impact Factor: 4.630 (2019) 10/1/21 9/10 11/1/21 10/6 Frequency: Monthly print issues 12/1/21 11/3 First Published: 2002 *Annual Meeting Issue

Peer Reviewed: Yes

Editor-in-Chief: Karen E. Knudsen, PhD, Sidney Kimmel Cancer Center, Thomas Jefferson University (Philadelphia, PA)

Molecular Cancer Research Rates

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Frequency 1x Multiple Website Statistics ETOCs Full Page $1,060 $960 12,000 users/month 6,200 recipients per month 1/2 Page $725 $625 65,000 page views/month $1,800 net per deployment 1/4 Page $505 $405 14,000 sessions/month Discount offered with multiple deployments 4-Color Rates: $700 Banner Ads (in addition to B/W rates) 28,000 US impressions/month Global $45.00 CPM Premium Opportunities: USA Only $50.00 CPM C2: +25% C3: +10% C4: +50% Guaranteed Position: +15% mcr.AACRJournals.org BLOOD CANCER DISCOVERY

Commitment and Issue Date Material Deadline 1/1 12/12 Blood Cancer Discovery covers innovative basic, 3/1 2/5 translational, and clinical research on all disease subtypes of leukemia, lymphoma and myeloma, as well as associated 5/1 4/3 diseases. Studies published in Blood Cancer Discovery 7/ 1 6 /2 describe mechanisms underlying disease biology; 9/1 8/1 diagnostic and therapeutic development; and translation of 11/1 9/29 these data into clinical trials.

Impact Factor: Coming in 2022

Frequency: Bimonthly print issues

First Published: 2020

Peer Reviewed: Yes

Editors-in-Chief: Riccardo Dalla-Favera, MD, Columbia University (New York, NY) and Kenneth C. Anderson, MD, Dana-Farber Cancer Institute (Boston, MA).

Blood Cancer Discovery Rates

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Frequency 1x Multiple Banner Ads ETOCs Full Page $1,060 $960 12,000 impressions/month 2,200 recipients per month 1/2 Page $725 $625 Global $45.00 CPM $1,800 net per deployment 1/4 Page $505 $405 USA Only $50.00 CPM Discount offered with multiple deployments 4-Color Rates: $700 (in addition to B/W rates)

Premium Opportunities: C2: +25% C3: +10% C4: +50% Guaranteed Position: +15% bcd.AACRJournals.org DIGITAL ADVERTISING

Contextual Advertising via PubGrade Advertising Solutions

The AACR Journals use PubGrade Advertising Solutions to offer our clients state-of-the art online advertising, including granular contextual and audience targeting along with superior reporting. We deliver banners in the context of relevant research articles only— making the best use of your budget.

Before the campaign • You tell us about the products, services, and content you want to promote. • We identify relevant keywords within scientific articles most likely read by your potential customers. • You can use any amount of keywords, phrases, or scientific concepts, which we combine using Boolean logic, to deliver your message alongside only the most relevant scientific articles. • Keywords can be modified according to your feedback. • We will share forecast data about potential campaign reach prior to campaign start.

During the campaign • You receive detailed monthly PDF reports going Ad Unit Sizes: 728 x 90 (leaderboard) beyond general metrics. 160 x 600 • Analyze your campaigns and optimize them to 300 x 250 achieve superior results.

Creative Types: JPEGs Rate: $50.00 CPM

Please send all materials and insertion orders to: Maura Paoletti, [email protected] // 443-512-8899 ext. 110

AACRJournals.org DIGITAL ADVERTISING SPECS

Banner Ads

- 900,000 US impressions/month across the AACR Journal platform

AACR Journals Platform AACR Journal Websites The AACR journal websites focus on readability and Ad Unit Sizes: 728 x 90 (leaderboard) discoverability. Advertisements have greater visibility with the addition of anchor banners. 120/160/300 x 600 Anchor Ads 300 x 250

Anchor ad: 728/970 x 90, 300 x 50 (mobile) Creative Types: GIFs, JPEGs, and SWFs Max. File Size: 99KB

3rd Party Tags Accepted (DFA, MediaMind, Pointroll, etc.)

Electronic Table of Contents (eTOC) Advertising

◀ Leaderboard AACR Journal Emails (eTOCs) Ad Unit Size – 728 x 90

Electronic Table of Contents Specs: • Creative Types: JPEGs • Creative Sizes: 728 x 90 • Max File Size: 39 KB

• 3rd Party Tags: ◀ Middle of content Yes, 1 x 1 Pixel For Impression Tracking • Can creative be animated: No, static only • TOC alerts sent via Mailchimp. Two positions: leaderboard and middle of content.

Please send all materials and insertion orders to: Maura Paoletti, [email protected] // 443-512-8899 ext. 110

AACRJournals.org PRINT ADVERTISING SPECS

Production and Mechanical Requirements (all AACR publications)

Mechanical Specifications: Mechanical Requirements: Trim Size: 8.125" x 10.875" Non-Bleed Sizes Bleed Sizes Live Area: Keep live matter .5" from trim Unit Sizes width x height width x height Binding: Perfect Full Page 7" x 10" 8.375" x 11.1875" Paper Stock: 50 lb. matte 1/2 Page Horizontal 7" x 5" 8.375" x 5.4375" (50 lb. glossy for Cancer Discovery) 1/2 Page Vertical 3.5" x 10" 4.0625" x 11.1875" Halftone Screen: 133-150 1/4 Page 3.5" x 5" n/a *Minimum 1/8” bleed required at head, face and foot

Print-ready Specifications: To ensure your advertisement is print-ready, please visit the Technology Center to view and download the correct preferences at https://caesar.sheridan.com/tsp_procedures/procedureFiles.php

Spread Bleed size: 16.75" x 11.875" Trim size: 16.25" x 10.875"

Reproduction Requirements: • PDF format is the preferred file format for file submission. • Only use Type 1 fonts - No true type fonts. • Images must be SWOP (CMYK or Grayscale) TIFF or EPS between 266 and 400 dpi. • Total area density should not exceed SWOP 300% TAC. • Do not embed ICC profiles within images. Do not use RGB or JPEG images. • Do not nest EPS files within other EPS files.

Print Production Coordinator: Maura Paoletti: The Walchli Tauber Group 443-512-8899 ext. 110 [email protected]

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Maura Paoletti National Sales Manager The Walchli Tauber Group 443-512-8899 ext. 110 [email protected] AACRJournals.org