Functions of the Circulatory System
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Heart Vein Artery
1 PRE-LAB EXERCISES Open the Atlas app. From the Views menu, go to System Views and scroll down to Circulatory System Views. You are responsible for the identification of all bold terms. A. Circulatory System Overview In the Circulatory System Views section, select View 1. Circulatory System. The skeletal system is included in this view. Note that blood vessels travel throughout the entire body. Heart Artery Vein 2 Brachiocephalic trunk Pulmonary circulation Pericardium 1. Where would you find the blood vessels with the largest diameter? 2. Select a few vessels in the leg and read their names. The large blue-colored vessels are _______________________________ and the large red-colored vessels are_______________________________. 3. In the system tray on the left side of the screen, deselect the skeletal system icon to remove the skeletal system structures from the view. The largest arteries and veins are all connected to the _______________________________. 4. Select the heart to highlight the pericardium. Use the Hide button in the content box to hide the pericardium from the view and observe the heart muscle and the vasculature of the heart. 3 a. What is the largest artery that supplies the heart? b. What are the two large, blue-colored veins that enter the right side of the heart? c. What is the large, red-colored artery that exits from the top of the heart? 5. Select any of the purple-colored branching vessels inside the rib cage and use the arrow in the content box to find and choose Pulmonary circulation from the hierarchy list. This will highlight the circulatory route that takes deoxygenated blood to the lungs and returns oxygenated blood back to the heart. -
Prep for Practical II
Images for Practical II BSC 2086L "Endocrine" A A B C A. Hypothalamus B. Pineal Gland (Body) C. Pituitary Gland "Endocrine" 1.Thyroid 2.Adrenal Gland 3.Pancreas "The Pancreas" "The Adrenal Glands" "The Ovary" "The Testes" Erythrocyte Neutrophil Eosinophil Basophil Lymphocyte Monocyte Platelet Figure 29-3 Photomicrograph of a human blood smear stained with Wright’s stain (765). Eosinophil Lymphocyte Monocyte Platelets Neutrophils Erythrocytes "Blood Typing" "Heart Coronal" 1.Right Atrium 3 4 2.Superior Vena Cava 5 2 3.Aortic Arch 6 4.Pulmonary Trunk 1 5.Left Atrium 12 9 6.Bicuspid Valve 10 7.Interventricular Septum 11 8.Apex of The Heart 9. Chordae tendineae 10.Papillary Muscle 7 11.Tricuspid Valve 12. Fossa Ovalis "Heart Coronal Section" Coronal Section of the Heart to show valves 1. Bicuspid 2. Pulmonary Semilunar 3. Tricuspid 4. Aortic Semilunar 5. Left Ventricle 6. Right Ventricle "Heart Coronal" 1.Pulmonary trunk 2.Right Atrium 3.Tricuspid Valve 4.Pulmonary Semilunar Valve 5.Myocardium 6.Interventricular Septum 7.Trabeculae Carneae 8.Papillary Muscle 9.Chordae Tendineae 10.Bicuspid Valve "Heart Anterior" 1. Brachiocephalic Artery 2. Left Common Carotid Artery 3. Ligamentum Arteriosum 4. Left Coronary Artery 5. Circumflex Artery 6. Great Cardiac Vein 7. Myocardium 8. Apex of The Heart 9. Pericardium (Visceral) 10. Right Coronary Artery 11. Auricle of Right Atrium 12. Pulmonary Trunk 13. Superior Vena Cava 14. Aortic Arch 15. Brachiocephalic vein "Heart Posterolateral" 1. Left Brachiocephalic vein 2. Right Brachiocephalic vein 3. Brachiocephalic Artery 4. Left Common Carotid Artery 5. Left Subclavian Artery 6. Aortic Arch 7. -
Pelvic Anatomyanatomy
PelvicPelvic AnatomyAnatomy RobertRobert E.E. Gutman,Gutman, MDMD ObjectivesObjectives UnderstandUnderstand pelvicpelvic anatomyanatomy Organs and structures of the female pelvis Vascular Supply Neurologic supply Pelvic and retroperitoneal contents and spaces Bony structures Connective tissue (fascia, ligaments) Pelvic floor and abdominal musculature DescribeDescribe functionalfunctional anatomyanatomy andand relevantrelevant pathophysiologypathophysiology Pelvic support Urinary continence Fecal continence AbdominalAbdominal WallWall RectusRectus FasciaFascia LayersLayers WhatWhat areare thethe layerslayers ofof thethe rectusrectus fasciafascia AboveAbove thethe arcuatearcuate line?line? BelowBelow thethe arcuatearcuate line?line? MedianMedial umbilicalumbilical fold Lateralligaments umbilical & folds folds BonyBony AnatomyAnatomy andand LigamentsLigaments BonyBony PelvisPelvis TheThe bonybony pelvispelvis isis comprisedcomprised ofof 22 innominateinnominate bones,bones, thethe sacrum,sacrum, andand thethe coccyx.coccyx. WhatWhat 33 piecespieces fusefuse toto makemake thethe InnominateInnominate bone?bone? PubisPubis IschiumIschium IliumIlium ClinicalClinical PelvimetryPelvimetry WhichWhich measurementsmeasurements thatthat cancan bebe mademade onon exam?exam? InletInlet DiagonalDiagonal ConjugateConjugate MidplaneMidplane InterspinousInterspinous diameterdiameter OutletOutlet TransverseTransverse diameterdiameter ((intertuberousintertuberous)) andand APAP diameterdiameter ((symphysissymphysis toto coccyx)coccyx) -
Severe Aortic Stenosis and the Valve Replacement Procedure
Severe Aortic Stenosis and the Valve Replacement Procedure A Guide for Patients and their Families If you’ve been diagnosed with severe aortic stenosis, you probably have a lot of questions and concerns. The information in this booklet will help you learn more about your heart, severe aortic stenosis, and treatment options. Your heart team will recommend which treatment option is best for you. Please talk with them about any questions you have. Table of Contents 4 About Your Heart 5 What Is Severe Aortic Stenosis? 5 What Causes Severe Aortic Stenosis? 7 What Are the Symptoms of Severe Aortic Stenosis? 8 Treatment Options for Severe Aortic Stenosis 10 Before a TAVR Procedure 12 What Are the Risks of TAVR? 2 3 About Your Heart What Is Severe See the difference between healthy and The heart is a muscle about the size of your fist. It is a pump that works nonstop to Aortic Stenosis? diseased valves send oxygen-rich blood throughout your entire body. The heart is made up of four The aortic valve is made up of two or three chambers and four valves. The contractions (heartbeats) of the four chambers push Healthy Valve the blood through the valves and out to your body. tissue flaps, called leaflets. Healthy valves open at every heart contraction, allowing blood to flow forward to the next chamber, and then close tightly to prevent blood from backing Pulmonic controls the flow of Aortic controls the flow of blood up. Blood flows in one direction only. This is Valve blood to the lungs Valve out of your heart to the important for a healthy heart. -
Vascular Density and Distribution in Neocortex
Zurich Open Repository and Archive University of Zurich Main Library Strickhofstrasse 39 CH-8057 Zurich www.zora.uzh.ch Year: 2019 Vascular density and distribution in neocortex Schmid, Franca ; Barrett, Matthew J P ; Jenny, Patrick ; Weber, Bruno Abstract: An amazingly wide range of complex behavior emerges from the cerebral cortex. Much of the information processing that leads to these behaviors is performed in neocortical circuits that span throughout the six layers of the cortex. Maintaining this circuit activity requires substantial quantities of oxygen and energy substrates, which are delivered by the complex yet well-organized and tightly-regulated vascular system. In this review, we provide a detailed characterization of the most relevant anatomical and functional features of the cortical vasculature. This includes a compilation of the available data on laminar variation of vascular density and the topological aspects of the microvascular system. We also review the spatio-temporal dynamics of cortical blood flow regulation and oxygenation, many aspects of which remain poorly understood. Finally, we discuss some of the important implications of vascular density, distribution, oxygenation and blood flow regulation for (laminar) fMRI. DOI: https://doi.org/10.1016/j.neuroimage.2017.06.046 Posted at the Zurich Open Repository and Archive, University of Zurich ZORA URL: https://doi.org/10.5167/uzh-146003 Journal Article Accepted Version The following work is licensed under a Creative Commons: Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License. Originally published at: Schmid, Franca; Barrett, Matthew J P; Jenny, Patrick; Weber, Bruno (2019). Vascular density and distribution in neocortex. -
Cardiovascular System Summary Notes the Cardiovascular System
Cardiovascular System Summary Notes The cardiovascular system includes: The heart, a muscular pump The blood, a fluid connective tissue The blood vessels, arteries, veins and capillaries Blood flows away from the heart in arteries, to the capillaries and back to the heart in the veins There is a decrease in blood pressure as the blood travels away from the heart Arterial branches of the aorta supply oxygenated blood to all parts of the body Deoxygenated blood leaves the organs in veins Veins unite to form the vena cava which returns the blood to the heart Pulmonary System This is the route by which blood is circulated from the heart to the lungs and back to the heart again The pulmonary system is exceptional in that the pulmonary artery carries deoxygenated blood and the pulmonary vein carries oxygenated blood Hepatic Portal Vein There is another exception in the circulatory system – the hepatic portal vein Veins normally carry blood from an organ back to the heart The hepatic portal vein carries blood from the capillary bed of the intestine to the capillary bed of the liver As a result, the liver has three blood vessels associated with it Arteries and Veins The central cavity of a blood vessel is called the lumen The lumen is lined with a thin layer of cells called the endothelium The composition of the vessel wall surrounding the endothelium is different in arteries, veins and capillaries Arteries carry blood away from the heart Arteries have a thick middle layer of smooth muscle They have an inner and outer layer of elastic fibres Elastic -
Blood Vessels
BLOOD VESSELS Blood vessels are how blood travels through the body. Whole blood is a fluid made up of red blood cells (erythrocytes), white blood cells (leukocytes), platelets (thrombocytes), and plasma. It supplies the body with oxygen. SUPERIOR AORTA (AORTIC ARCH) VEINS & VENA CAVA ARTERIES There are two basic types of blood vessels: veins and arteries. Veins carry blood back to the heart and arteries carry blood from the heart out to the rest of the body. Factoid! The smallest blood vessel is five micrometers wide. To put into perspective how small that is, a strand of hair is 17 micrometers wide! 2 BASIC (ARTERY) BLOOD VESSEL TUNICA EXTERNA TUNICA MEDIA (ELASTIC MEMBRANE) STRUCTURE TUNICA MEDIA (SMOOTH MUSCLE) Blood vessels have walls composed of TUNICA INTIMA three layers. (SUBENDOTHELIAL LAYER) The tunica externa is the outermost layer, primarily composed of stretchy collagen fibers. It also contains nerves. The tunica media is the middle layer. It contains smooth muscle and elastic fiber. TUNICA INTIMA (ELASTIC The tunica intima is the innermost layer. MEMBRANE) It contains endothelial cells, which TUNICA INTIMA manage substances passing in and out (ENDOTHELIUM) of the bloodstream. 3 VEINS Blood carries CO2 and waste into venules (super tiny veins). The venules empty into larger veins and these eventually empty into the heart. The walls of veins are not as thick as those of arteries. Some veins have flaps of tissue called valves in order to prevent backflow. Factoid! Valves are found mainly in veins of the limbs where gravity and blood pressure VALVE combine to make venous return more 4 difficult. -
In the Pulmonary Arteries, Capillaries, and Veins
Longitudinal Distribution of Vascular Resistance in the Pulmonary Arteries, Capillaries, and Veins JEROME S. BRODY, EDWARD J. STEMMLER, and ARTHu B. DuBois From the Department of Physiology, Division of Graduate Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 A B S T R A C T A new method has been described monary artery pressure averaged 20.4 cm H2O, for measuring the pressure and resistance to blood and pulmonary vein pressure averaged 9.2 cm flow in the pulmonary arteries, capillaries, and H2O. These techniques also provide a way of ana- veins. Studies were performed in dog isolated lyzing arterial, capillary, and venous responses to lung lobes perfused at constant flow with blood various pharmacologic and physiologic stimuli. from a donor dog. Pulmonary artery and vein volume and total lobar blood volume were mea- INTRODUCTION sured by the ether plethysmograph and dye- dilution techniques. The longitudinal distribution The arterioles are the major resistance vessels in of vascular resistance was determined by analyzing the systemic vascular bed (1, 2), but it is uncer- the decrease in perfusion pressure caused by a tain whether the greatest resistance to blood flow bolus of low viscosity liquid introduced into the in the lungs is in the arteries, capillaries, or veins vascular inflow of the lobe. (1, 3, 4). The pulmonary arteries were responsible for Piiper (5), in 1958, reasoned from Poiseuille's 46% of total lobar vascular resistance, whereas law that, during constant perfusion, injection into the pulmonary capillaries and veins accounted for the bloodstream of a bolus of fluid with viscosity 34 and 20% of total lobar vascular resistance different from that of blood would cause a per- respectively. -
Heart and Circulatory System Heart Chambers
160 Allen Street Rutland, Vermont 05701 www.rrmc.org 802.775.7111 Anatomy of the Heart Overview The heart is a muscular organ that pumps blood HEART AND throughout your body. It is positioned behind the CIRCULATORY SYSTEM lungs, slightly to the left side of the chest. Your heart is a bit larger than the size of your fist. Let's examine the structures of the heart and learn how blood travels through this complex organ. Right Side The heart is divided into two sides and four chambers. On the right side, blood that has already circulated through the body enters the heart through the superior vena cava and the inferior vena cava. The blood flows into the right atrium. When this chamber is full, the heart pushes the blood through the tricuspid valve and into the the next chamber - the right ventricle. From there, the blood is pushed out of the heart through the pulmonary valve. The blood travels through the pulmonary artery to the lungs, where it will pick up oxygen and give up carbon dioxide. HEART CHAMBERS Left Side On the left side of the heart, blood that has received oxygen from the lungs enters the heart through the pulmonary veins. The blood flows into the left atrium. It is pushed through the mitral valve into the left ventricle. Finally, it is pushed through the aortic valve and into the aorta. The aorta is the body's largest artery. It helps distribute the oxygen-rich Right Left blood throughout the body. Valves Now let's take a closer look at the valves. -
Avalus™ Pericardial Aortic Surgical Valve System
FACT SHEET Avalus™ Pericardial Aortic Surgical Valve System Aortic stenosis is a common heart problem caused by a narrowing of the heart’s aortic valve due to excessive calcium deposited on the valve leaflets. When the valve narrows, it does not open or close properly, making the heart work harder to pump blood throughout the body. Eventually, this causes the heart to weaken and function poorly, which may lead to heart failure and increased risk for sudden cardiac death. Disease The standard treatment for patients with aortic valve disease is surgical aortic valve Overview: replacement (SAVR). During this procedure, a surgeon will make an incision in the sternum to open the chest and expose the heart. The diseased native valve is then Aortic removed and a new artificial valve is inserted. Once in place, the device is sewn into Stenosis the aorta and takes over the original valve’s function to enable oxygen-rich blood to flow efficiently out of the heart. For patients that are unable to undergo surgical aortic valve replacement, or prefer a minimally-invasive therapy option, an alternative procedure to treat severe aortic stenosis is called transcatheter aortic valve replacement (TAVR). The Avalus Pericardial Aortic Surgical Valve System is a next- generation aortic surgical valve from Medtronic, offering advanced design concepts and unique features for the millions of patients with severe aortic stenosis who are candidates for open- heart surgery. The Avalus Surgical Valve The Avalus valve, made of bovine tissue, is also the only stented surgical aortic valve on the market that is MRI-safe (without restrictions) enabling patients with severe aortic stenosis who have the Avalus valve to undergo screening procedures for potential co-morbidities. -
Anatomy of the Digestive System
The Digestive System Anatomy of the Digestive System We need food for cellular utilization: organs of digestive system form essentially a long !nutrients as building blocks for synthesis continuous tube open at both ends !sugars, etc to break down for energy ! alimentary canal (gastrointestinal tract) most food that we eat cannot be directly used by the mouth!pharynx!esophagus!stomach! body small intestine!large intestine !too large and complex to be absorbed attached to this tube are assorted accessory organs and structures that aid in the digestive processes !chemical composition must be modified to be useable by cells salivary glands teeth digestive system functions to altered the chemical and liver physical composition of food so that it can be gall bladder absorbed and used by the body; ie pancreas mesenteries Functions of Digestive System: The GI tract (digestive system) is located mainly in 1. physical and chemical digestion abdominopelvic cavity 2. absorption surrounded by serous membrane = visceral peritoneum 3. collect & eliminate nonuseable components of food this serous membrane is continuous with parietal peritoneum and extends between digestive organs as mesenteries ! hold organs in place, prevent tangling Human Anatomy & Physiology: Digestive System; Ziser Lecture Notes, 2014.4 1 Human Anatomy & Physiology: Digestive System; Ziser Lecture Notes, 2014.4 2 is suspended from rear of soft palate The wall of the alimentary canal consists of 4 layers: blocks nasal passages when swallowing outer serosa: tongue visceral peritoneum, -
Lymph and Lymphatic Vessels
Cardiovascular System LYMPH AND LYMPHATIC VESSELS Venous system Arterial system Large veins Heart (capacitance vessels) Elastic arteries Large (conducting lymphatic vessels) vessels Lymph node Muscular arteries (distributing Lymphatic vessels) system Small veins (capacitance Arteriovenous vessels) anastomosis Lymphatic Sinusoid capillary Arterioles (resistance vessels) Postcapillary Terminal arteriole venule Metarteriole Thoroughfare Capillaries Precapillary sphincter channel (exchange vessels) Copyright © 2010 Pearson Education, Inc. Figure 19.2 Regional Internal jugular vein lymph nodes: Cervical nodes Entrance of right lymphatic duct into vein Entrance of thoracic duct into vein Axillary nodes Thoracic duct Cisterna chyli Aorta Inguinal nodes Lymphatic collecting vessels Drained by the right lymphatic duct Drained by the thoracic duct (a) General distribution of lymphatic collecting vessels and regional lymph nodes. Figure 20.2a Lymphatic System Outflow of fluid slightly exceeds return Consists of three parts 1. A network of lymphatic vessels carrying lymph 1. Transports fluid back to CV system 2. Lymph nodes 1. Filter the fluid within the vessels 3. Lymphoid organs 1. Participate in disease prevention Lymphatic System Functions 1. Returns interstitial fluid and leaked plasma proteins back to the blood 2. Disease surveillance 3. Lipid transport from intestine via lacteals Venous system Arterial system Heart Lymphatic system: Lymph duct Lymph trunk Lymph node Lymphatic collecting vessels, with valves Tissue fluid Blood Lymphatic capillaries Tissue cell capillary Blood Lymphatic capillaries capillaries (a) Structural relationship between a capillary bed of the blood vascular system and lymphatic capillaries. Filaments anchored to connective tissue Endothelial cell Flaplike minivalve Fibroblast in loose connective tissue (b) Lymphatic capillaries are blind-ended tubes in which adjacent endothelial cells overlap each other, forming flaplike minivalves.