Authors: Pallavi Subhraveti Ron Caspi Quang Ong Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000632515Cyc: Geobacillus stearothermophilus NUB3621 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari putrescine putrescine putrescine sn-glycerol spermidine 4-aminobutanoate 4-aminobutanoate 4-aminobutanoate ethanolamine spermidine spermidine spermidine uracil uracil 3-phosphate

predicted predicted ABC ABC transporter transporter RS14525 RS13805 RS01110 RS05760 RS09950 RS06340 RS04510 RS01240 RS10530 of sn- of spermidine/ glycerol 3- putrescine phosphate putrescine putrescine uracil uracil spermidine 4-aminobutanoate 4-aminobutanoate 4-aminobutanoate ethanolamine spermidine spermidine putrescine spermidine sn-glycerol 3-phosphate

Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Chlorinated Fatty Acid and Lipid Degradation Compound Degradation ditrans,octacis- a peptidoglycan UDP-N-acetyl- (1S,2R)-1- (2E,6Z,9Z,12Z,15Z,18Z) 3-(4- a peptidoglycan acetoacetyl-CoA hydrogenobyrinate cob(II)yrinate a,c- TCA cycle superpathway of glyoxylate bypass and TCA 4-chlorobenzoate undecaprenyldiphospho- with (L-alanyl-γ-D- α-D-muramoyl- di-trans,octa-cis a purine 2'- C-(indol-3- -tetracosahexaenoyl-CoA hydroxyphenyl) ser [2Fe-2S] iron-sulfur cluster biosynthesis 1,4-dihydroxy-2- siroheme biosynthesis NAD biosynthesis from 2- ubiquinol-8 biosynthesis adenosylcobalamin biosynthesis from cobyrinate a,c-diamide II N 10 -formyl-tetrahydrofolate biosynthesis thiamin diphosphate Aminoacyl-tRNA Charging fatty acid β-oxidation I with (L-alanyl- lipid II (meso ser diamide biosynthesis I acetone degradation N-acetyl-(N- glutamyl-meso-2,6- L-alanyl-γ-D- -undecaprenyl deoxyribonucleoside yl)glycerol enoyl-CoA 3-hydroxybutyryl- cobyrinic acid -3-hydroxy- naphthoate biosynthesis amino-3-carboxymuconate (prokaryotic) biosynthesis I (E. coli) γ-D-glutamyl-L- diaminopimelate purine nucleoside hydratase: serine (early cobalt insertion) degradation II acetylglucosaminyl) diaminopimeloyl- glutamyl-L- phospho-N-phosphate 3-phosphate tryptophan CoA a,c-diamide propanoyl-CoAenoyl-CoA semialdehyde cob(II)yrinate acetyl-CoA lysyl-D-alanyl- containing) phosphorylase: dehydratase: uroporphyrinogen-III all-trans- a tetrahydrofolate 2-[(2R,5Z)- tRNA charging a (3Z)-alk-3-enoyl-CoA (to acetoacetate) 4-chlorobenzoate muramoyl-L-alanyl- D-alanyl-D-alanine) peptidoglycan lysyl-D-alanine synthase H839_RS10635 dehydrogenase: synthase: uroporphyrinogen-III L-cysteine desulfurase chorismate aminocarboxymuconate a,c-diamide glutaminyl-tRNA gln D-alanine) peptidoglycan acetylmuramoyl- hydratase: H839_RS04660 siroheme synthase: 4-hydroxybenzoate octaprenyl 2-carboxy-4- 4-chlorobenzoate- γ-D-glutamyl-L-lysyl- pentapeptide glycosyltransferase: H839_RS09615 subunit beta: enoyl-CoA H839_RS10620 H839_RS04945 siroheme isochorismate semialdehyde arginine-- biosynthesis via isopropanol pentapeptide glycosyltransferase: pentapeptide H839_RS09480 serine cysteine H839_RS01450 diphosphate methylthiazol-5(2H dodecenoyl-CoA -CoA ligase: D-alanyl-D-alanine H839_RS01655 purine nucleoside H839_RS11320 hydratase: 3-hydroxybutyryl- synthase: synthase: tRNA ligase: transamidation isopropanol H839_RS01655 undecaprenyl-transferase: cobyrinic acid enoyl-CoA dehydratase: [+ 4 isozymes] 3-octaprenyl-4- )-ylidene]ethyl oxaloacetate peptidoglycan phosphorylase: H839_RS09480 H839_RS01450 desulfurase: H839_RS14605 H839_RS00590 D-isomerase: dehydrogenase: 4-chlorobenzoyl-H839_RS05955 diphospho-H839_RS04390N- tryptophan 3S-hydroxy- CoA a,c-diamide hydratase: precorrin-1 hydroxybenzoate methionine synthase: thiamine-phosphate citrate synthase: peptidoglycan a peptidoglycan α H839_RS11910 H839_RS04665 H839_RS10775 isochorismate quinolinate cob(I)yrinate phosphate glt H839_RS17290 H839_RS14125 a peptidoglycan glycosyltransferase: 2-deoxy- - synthase dehydrogenase: synthase: H839_RS10635 [+ 4 isozymes] H839_RS02865 pyrophosphorylase: arginine- H839_RS13965 coA glycosyltransferase: with (L-alanyl-γ-D- acetylmuramoyl- (6Z,9Z,12Z,15Z,18Z)- pyruvate [+ 4 isozymes] a,c-diamide glutamyl-tRNA Gln malate:quinone acetone with (L-alanyl- di-trans,octa-cisH839_RS14270 UMP γ D-ribose 1- a purine base subunit beta: H839_RS17290 H839_RS07325 4-coumaryl-CoA precorrin-1 uroporphyrinogen III thiE -tRNA di-trans,octa-cisH839_RS14270 glutamyl-meso-2,6- L-alanyl- -D- tetracosapentaenoyl-CoA (S)-3- 2-succinyl-5- nicotinate-nucleotide thiamin phosphate arg synthetase: oxidoreductase: γ-D-glutamyl-L- phosphate H839_RS06365 hydrogenobyrinate an S-sulfanyl-[L- methyltransferase: ATP:cob(I)alamin ligase: a (2E)-2-enoyl-CoA diaminopimeloyl- -undecaprenyl glutamyl-L- D-glyceraldehyde hydroxybutanoyl- uroporphyrinogen III enolpyruvyl- pyrophosphorylase: dihydrofolate reductase: H839_RS00045 H839_RS03370malate dehydrogenase: enoyl-CoA acetone -undecaprenyl a,c-diamide H839_RS07135 adenosyltransferase: argS an L-glutamyl- lysyl-D-alanyl- D-alanyl-D-alanine) diphosphate lysyl- D-alanine 3-phosphate trp CoA methyltransferase: cysteine desulfurase] 6-hydroxy-3- H839_RS13235 2-octaprenylphenol H839_RS01390 an L-arginyl- H839_RS13955 long-chain fatty hydratase: carboxylase diphosphate H839_RS11625 Gln 4-hydroxybenzoyl- D-alanine) [+ 3 isozymes] [tRNA Arg ] [tRNA ] acid--CoA ligase: H839_RS09480 pentapeptide H839_RS07135 scaffold protein cyclohexene- adenosyl- dihydrofolate reductase: (S)-malate citrate a 2,3,4-saturated 3-hydroxybutyryl- subunit beta: CoA pentapeptide citrate RS06700 citrate NaMN a tRNA Arg coenzyme A a 2,3,4-saturated (3R for iron-sulfur 1-carboxylate precorrin-2 H839_RS07495 glutamyl-tRNA fatty acidH839_RS05380 acyl-CoA enoyl-CoA CoA epimerase: H839_RS05270 [+ 3 isozymes] cobyrinate serine thiamin )-3-hydroxyacyl-CoA cluster assembly: synthase: nicotinate-nucleotide a,c-diamide amidotransferase: [+ 5 isozymes] dehydrogenase: hydratase: H839_RS17290 [+ 3 isozymes] a 7,8-dihydrofolate hydroxymethyltransferase: a 5-methyltetrahydrofolate diphosphate a nascent peptidoglycan ditrans,octacis- UDP-N-acetyl- 5'-deoxy-5'- (S)-2,3- a cis-delta9-3- precorrin-2 H839_RS15160 H839_RS14600 siroheme synthase: adenylyltransferase: 3-(all-trans gcv system: H839_RS04090 H839_RS01025 fumarate hydratase: malate synthase: aconitate hydratase: H839_RS00510 H839_RS10635 ADP-D-ribose OPC6-CoA acetyl-CoA (S)-4-amino-5- adenosyl- H839_RS17135 acetoacetate with (L-alanyl-γ-D- α-D-muramoyl- a myristoyl-[acp] hydroxyC28:1- an S-sulfanyl-[cysteine 2-succinyl-5- H839_RS01450 H839_RS12875 -octaprenyl) FMNH [+ 2 isozymes] H839_RS00850 H839_RS09845 a 2,3,4-saturated a 2,3,4-saturated (3S undecaprenyldiphospho- fluoroadenosine oxopentanoate dihydrodipicolinate glycerol RS05590 glycerol cys RS02485 cys cobyrate 2 H839_RS05535 [+ 11 isozymes] 4-hydroxybenzoate lipid II (meso trans,octacis ADP-ribose siroheme desulfurase]-[disordered- glutamyl-meso-2,6- N-acetyl-(N- L-alanyl-γ-D- purine nucleoside beta-ketoadipyl glutamate-1- dipicolinate enoyl-ACP [acp] 3-ketoacyl- enolpyruvyl-6-hydroxy- nicotinate adenine benzene-1,2-diol cysteinyl-tRNA an L-glutaminyl- fumarate hydratase: fatty acyl CoA )-3-hydroxyacyl-CoA diaminopimelate -decaprenyl synthase: synthase: cys 3-hydroxyacyl-CoA diaminopimeloyl- acetylglucosaminyl) glutamyl-meso-2,6- phosphorylase: pyrophosphatase: CoA thiolase: semialdehyde form scaffold sirohydrochlorin 3-demethylubiquinone- thymidylate synthase: synthetase: Gln synthase reductase: ACP 3-cyclohexene- dinucleotide H839_RS07330 adenosylcobalamin [tRNA ] H839_RS01565 dehydrogenase: containing) phosphate H839_RS06460 H839_RS01450 protein] complex 9 3-methyltransferase: H839_RS07490 fumarate cis-aconitate D-alanyl-D-alanine) peptidoglycan muramoyl-L-alanyl-γ- diaminopimeloyl- H839_RS09615 H839_RS10500 aminotransferase: subunit A: H839_RS03255 reductase: 1-carboxylate (R)-1-amino- salvage from cobalamin H839_RS00055 an L-cysteinyl- phospho-N- guanine RS17360 guanine cysteine siroheme synthase: NAD synthetase: aconitate hydratase: H839_RS17290 pentapeptide glycosyltransferase: D-isoglutaminyl-N-(β- D-alanyl-D-alanine purine nucleoside ADP-ribose beta-ketoadipyl H839_RS01790 cys RS10380 cys (1R,6R)-2- H839_RS08740 Cys acetyl-CoA glyoxylate acetylmuramoyl- H839_RS05110 enoyl-ACP fabG sirohydrochlorin desulfurase: 2-propanol O adenosylcobyrate [tRNA ] H839_RS05535 H839_RS01655 H839_RS01450 2-methoxy- Cys succinate dehydrogenase: beta-ketoadipyl phosphorylase: pyrophosphatase: CoA thiolase: succinyl-6- H839_RS13215 5,6-dimethylbenzimidazole cob(I)alamin a tRNA protocatechuate D-asparaginyl)-L-lysyl-peptidoglycan pentapeptide glutamate-1- dipicolinate reductase: [+ 5 isozymes] H839_RS10775 6-(all-trans- -2-phosphate a (6S)-5-formyltetrahydrofolate H839_RS13655 peptidoglycan H839_RS11945 a (9Z)-3- sirohydrochlorin hydroxy-2,4- sirohydrochlorin cob(I)alamin CoA thiolase: D-alanyl-D-alanineglycosyltransferase: transferase: H839_RS11910 H839_RS10615 semialdehyde synthase H839_RS01730 + adenosylcobinamide- 5,10- 5,10-methylene- Amine and Polyamine Biosynthesis isocitrate lyase: a nascent peptidoglycan decaprenyl- OPC8-3- oxooctacos- cobaltochelatase: [+ 4 isozymes] ferrochelatase: NAD octaprenyl)phenol nicotinate-nucleotide-- [+ 2 isozymes] H839_RS10500 glycosyltransferase: H839_RS01655 5-fluoro-5- aminotransferase: a (2E)-tetradec- guanine RS00880 guanine a [cysteine desulfurase]- cyclohexadiene- methylenetetrahydrofolate adenolsyltransferase/ a 2,3,4-saturated a 2,3,4-saturated γ diphospho-H839_RS04390N- D-ribofuranose subunit B: 9-enoyl-[acp] predicted H839_RS01480 phosphate synthase: dimethylbenzimidazole tetrahydrofolate H839_RS02730 withH839_RS14270 (L-alanyl- -D- UMP deoxy-D-ribose adenine AMP ketoacyl-CoA H839_RS07285 S-sulfanyl-[disordered- 1-carboxylate cobinamide fatty acyl CoA beta-ketoadipyl 3-oxoacyl-CoA di-trans,octa-cis peptidoglycan acetylmuramoyl- H839_RS13495 spoVFB 2-enoyl-[acp] ATP-driven H839_RS11655 phosphoribosyltransferase: reductase: H839_RS02870 cyclohydrolase: putrescine glutamyl-meso-2,6- 1-phosphate 5-phosphate val val cobalt- form scaffold synthase: ATP-dependent glutathionylspermidine succinate D-threo-isocitrate CoA thiolase: -undecaprenyl di-trans,octa-cis glycosyltransferase: pentapeptide 5-aminolevulinate dipicolinate transporter siroheme adenosyl- H839_RS07335 H839_RS12225 biosynthesis I isocitrate dehydrogenase: diaminopimeloyl- a peptidoglycan ile ile sirohydrochlorin protein] complex H839_RS14595 2-methoxy-6-all a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate adenolsyltransferase: gln biosynthesis H839_RS10615 diphosphate -undecaprenyl H839_RS14270 of L-leucine/ cobinamide H839_RS13960 succinate D-alanyl-D-alanine) dimer (E. faeciums) predicted leu leu cysteine (1R,6R)-6-hydroxy-2- trans-octaprenyl- α-ribazole H839_RS07345 diphosphate L-isoleucine/ phosphate an L-glutaminyl- succinyl-CoA synthetase isocitrate dehydrogenase: pentapeptide ABC desulfurase: succinylcyclohexa-2,4- 2-methoxy-1,4- 5'-phosphate 5,10-methylene- arg glutathione spermidine urea urea L-valine GTP:adenosylcobinamide- ATP:cob(I)alamin Gln subunit beta: sucC H839_RS01660 transporter H839_RS10775 diene-1-carboxylate benzoquinol tetrahydrofolate [tRNA ] glutathionylspermidine phosphate α-ribazole-5'-P adenosyltransferase: Gln of urea O-succinylbenzoate 2-octaprenyl- cyclohydrolase: a tRNA undecaprenyl-diphospho- ditrans,octacis- an [apo BCAA 3-oxo- cobalt-factor III [+ 4 isozymes] guanylyltransferase: phosphatase: thiazole biosynthesis I (E. coli) H839_RS11625 synthase: H839_RS09065 acetyl-CoA 5'-deoxy-5'- predicted an S-sulfanyl-[cysteine 6-methoxy-1,4- glutathione H839_RS12225 Aldehyde Degradation N-acetylmuramoyl-L- 4-methyl-2- (6Z,9Z,12Z,15Z,18Z,21Z) OPC4-CoA acetyl-CoA an octanoyl-[acp] a butanoyl-[acp] synthase: adenosylcobalamin agmatine glutathionylspermidine succinyl-CoA 2-oxoglutarate UDP-N-acetyl- undecaprenyldiphospho- dehydrogenase chloroadenosine 2'-deoxyguanosine IMP desulfurase]-S- benzoquinone H839_RS11645 H839_RS11635 6 a sugar RS11075 a sugar ATP-driven H839_RS03460 biosynthesis alanyl-γ-D-glutamyl-L- α-D-glucosamine N-acetyl-(N- oxopentanoate E2 protein] N -tetracosahexaenoyl-CoA purine nucleoside beta-ketoadipyl enoyl-ACP enoyl-ACP val val sulfanyl-[disordered- methylase: adenosylcobinamide- an N 10 -formyltetrahydrofolate UDP-diphospho- branched-chain beta-ketoadipyl deoxycytidine transporter α-ribazole cys agmatinase: methylglyoxal lysyl- D-alanyl-D-alanine acetylglucosaminyl) -lipoyl-L-lysine phosphorylase: CoA thiolase: reductase: reductase: nucleotidase: ile ile form scaffold 2-succinylbenzoate flavin biosynthesis I (bacteria and plants) H839_RS11375 GDP methylglyoxal muramoylpentapeptide beta-N- alpha-keto acid CoA thiolase: kinase: of L-leucine/ cys glt glutamyl-tRNA H839_RS06875 degradation I muramoyl-L-alanyl- H839_RS09615 H839_RS10500 H839_RS03255 H839_RS03255 H839_RS12610 leu leu protein] complex 6-methoxy-3- glt degradation II dehydrogenase H839_RS10500 H839_RS17905 L-isoleucine/ cobalt-precorrin-3 cysteine cysteine synthetase: acetylglucosaminyltransferase: γ-D-isoglutaminyl- purine nucleoside beta-ketoadipyl predicted O-succinylbenzoate- methyl-2-all- agmatinase: 2-oxoglutarate purine nucleotides degradation II (aerobic) Nucleoside and Nucleotide Degradation ditrans,octacis- beta-ketoadipyl enoyl-ACP enoyl-ACP [+ 2 isozymes] L-valine cobalamin desulfurase: methylglyoxal H839_RS00595 N-(β-D-asparaginyl) subunit E2: deoxyguanosine ABC desulfurase: -CoA ligase: trans-octaprenyl- γ-L-glutamyl- H839_RS00045 an L-glutamyl- H839_RS17330 dehydrogenase: undecaprenyldiphospho-N- peptidoglycan phosphorylase: CoA thiolase: reductase: reductase: GTP synthase: TCA cycle II (plants and fungi) methylglyoxal H839_RS04085 CoA thiolase: kinase: a sugar a sugar H839_RS10775 1,4-benzoquinol H839_RS10775 L-cysteine [tRNA Glu ] H839_RS03865 lactoylglutathione -L-lysyl-D-alanineglycosyltransferase: H839_RS11910 H839_RS10615 H839_RS01730 H839_RS01730 inosine transporter H839_RS10150 H839_RS11640 putrescine Glycolysis glyoxalase: acetyl-(N-acetylglucosaminyl) a [apo BCAA dehydrogenase H839_RS10615 OPC6-3- riboflavin RS07575 riboflavin [+ 4 isozymes] [+ 4 isozymes] superpathway of heme a tRNA glu lyase: UDP H839_RS01655 [+ 2 isozymes] docosahexaenoyl- 5-chloro-5- H839_RS17910 a (2E)-oct- a (2E)-but- of a sugar a [cysteine O-succinylbenzoic glutathione [+ 3 isozymes] AMP H839_RS02330 muramoyl-L-alanyl- E2 protein] N 6 -S-[3- acetyl-CoA ketoacyl-CoA GTP an [L-cysteine biosynthesis from H839_RS12045 CoA adenine deoxyribose dGMP 2-enoyl-[acp] 2-enoyl-[acp] desulfurase]-(S- acid--CoA ligase: synthetase: oxaloacetate (R)-S- [+ 2 isozymes] γ-D-glutamyl-L-lysyl- peptidoglycan methylbutanoyl]dihydrolipoyl- cobalt-precorrin-4 cyclohydrolase: desulfurase]-S- uroporphyrinogen-III glycolysis III (from glucose) 1-phosphate a sugar RS05175 a sugar sulfanyl) -[disordered- H839_RS14585 adenosylcobalamin a ThiS sulfur- H839_RS02530 lactoylglutathione (R)-lactate D-alanyl-D-alanine di-trans,octa-cis a glycosyltransferase:peptidoglycan L-lysine 2 H839_RS11820 sulfanyl-L-cysteine nucleotidase: form scaffold 3-demethylubiquinol-8 carrier protein uroporphyrinogen-III -undecaprenyl H839_RS14270dimer thiamin RS02435 thiamin cobalt-precorrin- 4-(2'-carboxyphenyl) 2,5-diamino-6-(5- cysteine D-glucopyranose H839_RS12610 glyoxalase II: glutathione uroporphyrinogen citrate synthase: diphosphate (tetrapeptide) 4 C(11)- protein] complex -4-oxobutyryl-CoA phospho-D-ribosylamino) desulfurase: ThiS isoleucine- [+ 2 isozymes] IMP H839_RS12485 3-demethylubiquinone- decarboxylase: ile H839_RS13965 methyltransferase: pyrimidin-4(3H)-one H839_RS10775 adenylyltransferase: -tRNA glucokinase: a sugar RS02505 a sugar dihydroxynaphthoic 9 3-methyltransferase: H839_RS02650 malate dehydrogenase: H839_RS07315 ligase: ileS an L-isoleucyl- H839_RS12400 adenosine inosine-5- (R)-lactate ditrans,octacis- a [dinitrogen an [amino group carrier 38- trp RS02600 trp acid synthetase: diaminohydroxyphosphoribosylaminopyrimidine H839_RS08740 [+ 4 isozymes] H839_RS02470 (S)-malate H839_RS13955 citrate pyruvate a single (2E,6Z,9Z,12Z,15Z,18Z,21Z) a uridine molybdenum cofactor biosynthesis a [ThiI sulfur- a carboxy- coproporphyrinogen III Ile a purine ω α protein]-C-terminal-γ- a decanoyl-[acp] a stearoyl-[acp] cobalt- a [cysteine desulfurase]- H839_RS14590 deaminase: H839_RS11830 [tRNA ] glucokinase: monophosphate stranded DNA undecaprenyldiphospho- arsenate reductase]-N - - -tetracosaheptaenoyl-CoA 40 in tRNA dGTP a tRNA Ile ribonucleoside precorrin-5A [scaffold protein- ubiquinol-8 D-glyceraldehyde carrier protein]-S- adenylated-[ThiS fumarate hydratase: H839_RS12500 adenosine dehydrogenase: exodeoxyribonuclease N-acetyl-(N- ( ADP-D-ribosyl) enoyl-CoA (L-glutamyl)-L-glutamate tRNA enoyl-ACP enoyl-ACP a sugar RS16450 a sugar 1,4-dihydroxy-2- 5-amino-6-(5-phospho- a small subunit of purine nucleoside acetylglutamate nucleoside- (2Fe-2S)] complex 3-phosphate sulfanyl-L-cysteine sulfur-carrier protein] H839_RS00850 aconitate hydratase: D-glucopyranose deaminase: H839_RS04250 VII small subunit: acetylglucosaminyl) -L-arginineADP-ribosyl- hydratase: pseudouridine reductase: reductase: a short a short naphthoyl-CoA D-ribosylamino)uracil molybdopterin phosphorylase: H839_RS10635 kinase: triphosphate 1-deoxy-D- fumarate hydratase: H839_RS05535 6-phosphate H839_RS17920 inosine-5- H839_RS12215 muramoyl-L-alanyl-γ-D- (dinitrogen synthase A: H839_RS03255 H839_RS03255 chain RS17455 chain 5-amino-6-(5- synthase tyr pyruvate H839_RS09615 H839_RS03055 diphosphatase: xylulose-5- adenylate:persulfide thiazole biosynthesis II (Bacillus) H839_RS01565 GMP monophosphate exodeoxyribonuclease isoglutaminyl-L-lysyl- reductase) enoyl-CoA an [amino group carrier H839_RS00310 fatty acid fatty acid cys molybdopterin- protoporphyrinogen IX glucose-6- peptidoglycan enoyl-ACP enoyl-ACP H839_RS13615 a sugar RS06940 a sugar cobalt- phosphoribosylamino) transferase: inosine VII large subunit: (glycyl) -D-alanyl-D-alanine purine nucleoside hydrolase: hydratase: tRNA D-ribulose 5-phosphate synthase phosphate leucyl-tRNA fumarate cis-aconitate phosphate dehydrogenase: 5 glycosyltransferase: protein]-C-terminal- reductase: reductase: precorrin-5B a [co-chaperone]- uracil reductase: H839_RS02470 leu phosphorylase: H839_RS16780 H839_RS09480 1,4-dihydroxy- synthase: protoporphyrinogen synthetase: aconitate hydratase: isomerase: nucleotidase: H839_RS17875 H839_RS12220 H839_RS01655 a [dinitrogen (3S)-hydroxy- γ-(5-phospho-L- pseudouridine H839_RS01730 H839_RS01730 dGMP cobalt-precorrin- [scaffold protein- H839_RS11830 cysteine adenylyltransferase: cys H839_RS11910 lactate RS01415 lactate 2-naphthoate 3,4-dihydroxy- H839_RS12205 oxidase: H839_RS14445 succinate dehydrogenase: H839_RS05535 purine nucleoside H839_RS12610 a single-stranded a ribonucleoside reductase]- ADP-D-ribose glutamyl)-L-glutamate synthase B: truB a (2E)-dec- a (2E)-octadec- (2Fe-2S)] complex H839_RS02470 a ThiS sulfur- an L-leucyl- H839_RS14865 (6Z,9Z,12Z,15Z,18Z,21Z) 38- 6A synthase: 2-butanone 5-amino-6-(5-phospho- desulfurase: H839_RS02660 oligodeoxyribonucleotide 5'-monophosphate peptidoglycan ribose-1-arsenate a purine base L-arginine a pseudouridine SSQ1 a carboxy- 1-deoxy-D-xylulose a thiocarboxy- carrier protein [tRNA Leu ] H839_RS13655 phosphorylase: [+ 2 isozymes] XMP -tetracosahexaenoyl-CoA 2-enoyl-[acp] 2-enoyl-[acp] a sugar RS03505 a sugar H839_RS07300 D-ribitylamino)uracil H839_RS10775 2-iminoacetate cysteine di-trans,octa-cisglycosyltransferase: 40 in tRNA 4-phosphate adenylated [ThiS-Protein] a tRNA Leu [+ 2 isozymes] F6P H839_RS11910 a peptidoglycan chaperone: [+ 4 isozymes] 5-phosphate desulfurase: ThiS protoporphyrin IX Alcohol Degradation H839_RS14270-undecaprenyl cobalt- synthase: [small subunit of guanosine nucleotidase: dimer (S. aureus) a corrin BtuC a corrin dnaK NAD biosynthesis an [L-cysteine H839_RS10775 adenylyltransferase: purine nucleoside diphosphate precorrin-6A a [chaperone-ATP]- H839_RS11820 succinate isocitrate dehydrogenase:D-threo-isocitrate 6-phosphofructokinase: desulfurase]-S- molybdopterin thiazole H839_RS02470 ferrochelatase: phosphorylase: H839_RS12610 predicted I (from aspartate) [+ 4 isozymes] H839_RS13990 purine nucleoside glycerol and glycerophosphodiester degradation [co-chaperone]- 1-deoxy-L-glycero- sulfanyl-L-cysteine synthase] synthase: an [L-cysteine a carboxy- H839_RS02655 H839_RS01660 H839_RS09615 [+ 2 isozymes] ABC [scaffold protein- tetrulose 4-phosphate ARP H839_RS02465 succinyl-CoA synthetase isocitrate dehydrogenase: fructose 1,6- phosphorylase: an oxidized a peptidoglycan 4-hydroxybenzoyl- a peptide with a sugar a sugar D-glyceraldehyde desulfurase]-S- adenylated-[ThiS valine- N 5 -methyltetrahydromethanopterin acetyl-CoA transporter 2+ 2+ a purine an N-terminal a hexanoyl-[acp] Cd RS02190 Cd (2Fe-2S)] complex asp molybdopterin GTP ferroheme b val subunit beta: sucC H839_RS13960 bisphosphate hypoxanthine H839_RS11910 xanthosine a glycerophosphodiester factor 420 dimer with CoA met a protein thr dATP cobalt- 3-phosphate sulfanyl-L-cysteine sulfur-carrier protein] -tRNA 5,10-methylene of a sugar L-aspartate 2-[(2R,5Z)-2-carboxy- purine nucleoside pentapeptide ribonucleoside beta-ketoadipyl Clp protease L-methioninemethionine enoyl-ACP precorrin-6B 6,7-dimethyl-8- synthase ligase: valS purine nucleoside aromatic amino acid threonine SSQ1 oxidase: 4-methylthiazol-5(2H)- 1-deoxy-D- an L-valyl- tetrahydromethanopterin stems (meso- CoA thiolase: ClpX: aminopeptidase: reductase: nucleoside- tetrahydrofolate biosynthesis sulfurtransferase: cyclic pyranopterin cysteine Val fructose- phosphorylase: dehydratase: ribityllumazine xylulose-5- gly [tRNA ] succinyl-CoA 2-oxoglutarate glycerophosphodiester reductase: H839_RS02300 phosphorylase: H839_RS10500 aminotransferase: triphosphate predicted chaperone H839_RS13240 H839_RS02470 monophosphate ylidene]ethyl phosphate bisphosphate H839_RS09615 diaminopimelateN-acetylmuramoyl- H839_RS00020 H839_RS00265 H839_RS03255 synthase: ribH desulfurtrase: Val xanthine purine nucleoside glycerol H839_RS09615 H839_RS03935 H839_RS07505 ABC allantoin RS06865 allantoin ATPase: dnaK heme biosynthesis 2-iminosuccinate 6-hydroxymethyl- phosphate a tRNA phosphodiesterase: 5,10-methylene containing)L-alanine beta-ketoadipyl diphosphatase: a sugar a sugar synthase: H839_RS14235 glycine oxidase: aldolase: dehydrogenase: phosphorylase: aromatic amino acid [+ 7 isozymes] methionine enoyl-ACP threonine transporter II (anaerobic) 7,8-dihydropterin 4-aminobenzoate a thiocarboxylated synthase: H839_RS06025 tetrahydromethanopterin amidase: purine nucleoside CoA thiolase: H839_RS13615 6,7-dimethyl-8-(1- quinolinate H839_RS03010 H839_RS02455 H839_RS06975 H839_RS01355 guanine H839_RS09615 a peptidoglycan aminotransferase: a peptide a peptide aminopeptidase: reductase: dehydratase: of a sugar cobalt-precorrin-7 a [chaperone- diphosphate cyclic H839_RS12205 glycerol glycerophosphodiester reductase: H839_RS14675 H839_RS00330 phosphorylase: H839_RS10615 dAMP an [2Fe-2S] D-ribityl)lumazine synthetase: dihydropteroate [small subunit of 2-oxoglutarate H839_RS07100 H839_RS01730 ADP]-[disordered- uroporphyrinogen-III a thiocarboxy- fructose- xanthine purine nucleoside kinase: phosphodiesterase: a reduced 5,10-methylene- L-alanyl-γ-D- dimer with H839_RS11910 4-hydroxybenzoyl- H839_RS14885 H839_RS09545 a cation RS01550 a cation synthase: molybdopterin pyranopterin phosphopantothenate biosynthesis I 1-deoxy-D-xylulose [+ 2 isozymes] α 2-oxo-4- a (2E)-hex- cluster protein uroporphyrinogen riboflavin H839_RS13230 [ThiS-Protein] 2-iminoacetate alanine- dehydrogenase: bisphosphate dehydrogenase: phosphorylase: factor 420 tetrahydromethanopterin glutamyl-meso-2,6- pentapeptide -D-ribose- acetyl-CoA a peptide met 2-oxobutanoate a sugar RS06220 a sugar form scaffold H839_RS18210 synthase] phosphate 5-phosphate glpK H839_RS07235 a purine base methylthiobutanoate 2-enoyl-[acp] decarboxylase: synthase 7,8- -tRNA H839_RS03865 aldolase: H839_RS07765 H839_RS11910 diaminopimeloyl- stem (meso- 1-phosphate protein] complex quinolinate ala H839_RS02650 subunit alpha: dihydropteroate 3-methyl-2-oxobutanoate [+ 3 isozymes] H839_RS17245 D-alanyl-D-alanine diaminopimelate non- molybdopterin thiazole trans, trans-farnesyl ligase: sn-glycerol cobalt-precorrin-8 coproporphyrinogen III H839_RS11825 folylpolyglutamate containing) a heme RS05165 a heme chaperonin nicotinate-nucleotide synthase: synthase: diphosphate biosynthesis alaS an L-alanyl- K + RS00475 K + synthase: 3-methyl-2-oxobutanoate xanthine 3-phosphate molecular pyrophosphorylase: H839_RS03030 [tRNA Ala ] radical SAM riboflavin hydroxymethyltransferase: H839_RS02465 triosephosphate H839_RS13470 Ala superpathway of purine deoxyribonucleosides degradation glycerol-3- chaperone H839_RS13235 H839_RS11210 IPP a tRNA isomerase: tpiA xanthine an odd numbered UDP-N-acetyl- a non-methylated protein: D-glyceraldehyde + an electron- 6-trans-3-oxo- ATPase: dnaK 7,8-dihydrofolate 2-[(2R,5Z)-2-carboxy- isopentenyl TCA cycle VIII (helicobacter) DHAP dehydrogenase: phosphate α NADH H (R)-citramalate 3-phosphate straight chain -D-muramoyl- di-trans,octa-cis transfer quinone tridecenoyl-CoA trp ribosomal a dodecanoyl-[acp] a palmitoyl-[acp] + + D-ribose RS06935 D-ribose H839_RS02985 riboflavin kinase: NaMN monoglutamate molybdopterin dehydrogenase, GTP K RS00470 K an [Fe-S cluster a [disordered- 2-dehydropantoate 4-methylthiazol-5(2H)- pyrophosphate H839_RS01355 2,3,4-saturated L-alanyl-γ-D- -undecaprenyl NADH:ubiquinone beta-ketoadipyl protein L11 isopropylmalate cobyrinate [+ 6 isozymes] H839_RS05080 glyceraldehyde- 2'-deoxyguanosine aerobic: aromatic amino acid ribosomal enoyl-ACP enoyl-ACP biosynthesis form [Fe-S] cluster nicotinate-nucleotide molybdopterin ylidene]ethyl phosphate isomerase: oxaloacetate xanthine fatty acidlong-chain fatty glutamyl-L-lysyl- phosphate oxidoreductase CoA thiolase: isomerase: nucleoside- 2-dehydropantoate 2- thiazole 3-phosphate H839_RS11090 phospho-N- aminotransferase: protein L11 reductase: reductase: cobyrinic acid chaperone]-ATP scaffold protein] protoporphyrinogen IX FMN adenylyltransferase: adenylyltransferase: H839_RS11465 dehydrogenase: 2'-deoxyadenosine acid--CoA ligase: D-alanyl-D-alanine subunit H: H839_RS10500 H839_RS13560 triphosphate reductase: H839_RS04345 tautomerase: asn asparagine- dehydrogenase: acetylmuramoyl- H839_RS03935 methyltransferase: H839_RS03255 H839_RS03255 a,c-diamide DMAPP H839_RS02680 H839_RS17055 diphosphatase: K + RS00465 K + H839_RS12875 H839_RS03020 -tRNA H839_RS13920 H839_RS07765 DHAP pentapeptide beta-ketoadipyl H839_RS12775 enoyl-ACP enoyl-ACP isopropylmalate synthase: FMN a 7,8-dihydrofolate molybdopterin 2-dehydropantoate 2- H839_RS02450 malate:quinone citrate synthase: an odd numbered aromatic amino acid a methylated H839_RS13615 nicotinate adenine 2-(2-carboxy-4- ligase: asnC an L-asparaginyl- purine nucleoside [+ 5 isozymes] transferase: NADH CoA thiolase: reductase: reductase: isomerase: adenylyltransferase: adenine reductase: H839_RS02400 farnesyl- oxidoreductase: H839_RS13965 urate straight chain undecaprenyl- aminotransferase: ribosomal H839_RS07325 dinucleotide Asn 13-DPG adenosine phosphorylase: diphosphate AMP dehydrogenase: H839_RS10615 H839_RS13565 GMP H839_RS05080 dihydrofolate β methylthiazol-5- diphosphate [tRNA ] H839_RS03370 2,3,4-saturated diphospho-H839_RS04390N- H839_RS14885 protein L11 H839_RS01730 H839_RS01730 biotin biosynthesis from dinucleotide -alanine (R)-pantoate tRNA Asn H839_RS11910 H839_RS17060 4-trans- a (2E)-dodec- a (2E)-hexadec- cobyrinic acid yl)ethyl phosphate deaminase: acetylmuramoyl- acetyl-CoA citraconate Mg 2+ RS04865 Mg 2+ 8-amino-7-oxononanoate I protoporphyrin IX NAD synthetase: NAD synthetase: reductase: molybdopterin synthase: (S)-malate citrate phosphoglycerate fatty acyl CoA an electron- undecenoyl-CoA indole-3-pyruvate a,c-diamide FAD H839_RS17920 purine nucleoside UMP γ NAD + 2-enoyl-[acp] 2-enoyl-[acp] H839_RS13215 H839_RS13215 H839_RS01390 molybdenumtransferase: H839_RS12210 kinase: pgk L-alanyl- -D- transfer quinol synthase: 8-amino-7- phosphorylase: ferrochelatase: dihydrofolate H839_RS03020 pantoate--beta-alanine guanylyl molybdenum geranyl fumarate hydratase: purine nucleoside glutamyl-L-lysyl- H839_RS04945 oxononanoate NAD + aconitate hydratase: 3-phospho- H839_RS09615 H839_RS02655 reductase: MoO - ligase: H839_RS11205 H839_RS00850 phosphorylase: D-alanyl-D-alanine 2+ 2+ adenosylmethionine- 2 cofactor biosynthesis S-adenosyl-L-methionine cycle I diphosphate Mg RS09670 Mg cob(II)yrinate molybdopterin aspartate- fumarate hydratase: H839_RS05535 D-glycerate H839_RS11910 2'-deoxyinosine -8-amino-7- H839_RS07495 MoO - 2 farnesyl- -tRNA a,c-diamide oxononanoate ferroheme b cofactor asp H839_RS01565 purine nucleoside (R)-pantothenate molybdopterin diphosphate a (3R)-3- UDP-3-O-(3- decaprenyl- 6-cis, 3-oxo- a 2'- trans-dec-2- a tetrahydrofolate ligase: fumarate cis-aconitate phosphorylase: purine nucleoside glycerophosphoserine jasmonoyl-CoA acetyl-CoA citraconate aminotransferase cofactor SAM hydroxytetradecanoyl- hydroxymyristoyl) pyrophosphoryl-(N a protein deoxyribonucleoside di-trans,poly-cis-undecaprenyl molybdopterin- synthase: aspS an L-aspartyl- aconitate hydratase: tridecenoyl-CoA enoyl-CoA dIDP Mo 2+ RS03005 Mo 2+ BioA: H839_RS15275 pantothenate kinase: H839_RS09615 phosphorylase: α glycerophosphodiester beta-ketoadipyl beta-ketoadipyl 5'-diphosphate enoyl-CoA isopropylmalate 7,8- guanine H839_RS12210 asp 2-phospho- [acp] UDP-3-O-(3-- -D-glucosamine -acetylglucosamine) ATP-dependent ribonucleotide- phosphate biosynthesis [tRNA ] H839_RS05535 H839_RS11910 nucleoside H839_RS18180 asp fumarate reductase: sdhA D-glycerate -N-acetylmuramyl- phosphodiesterase: CoA thiolase: CoA thiolase: hydratase: isomerase: diaminopelargonate pyridoxal 5'-phosphate salvage I dinucleotide S-adenosylmethionine (2E,6E)-farnesyl tRNA hydroxymyristoyl) peptidoglycan protease diphosphate (2E,6E)-farnesyl purine nucleoside (pentapeptide) H839_RS06025 H839_RS10500 H839_RS10500 H839_RS10635 H839_RS13560 diphosphate dethiobiotin thioredoxin pathway biosynthesis synthetase: diphosphate enolase: glucosamine N- glycosyltransferase: subunit HslV: reductase (R)-4'-phosphopantothenate phosphorylase: kinase: 2+ 2+ diphosphate protein A: H839_RS14500 acyltransferase: glycerophosphodiester beta-ketoadipyl beta-ketoadipyl H839_RS04810 subunit beta: enoyl-CoA isopropylmalate Mo RS08735 Mo synthetase: di-trans,poly-cis-decaprenyl eno H839_RS01655 H839_RS11365 pyridoxine pyridoxamine H839_RS02980 H839_RS09615 H839_RS16315 phosphodiesterase: CoA thiolase: CoA thiolase: H839_RS02375 hydratase: isomerase: H839_RS15280 diphosphate:isopentenyl- met SAH succinate isocitrate dehydrogenase:D-threo-isocitrate phosphoenol UDP-2-N,3-O-bis[(3R)- peptidoglycan a peptide a peptide an oxidized α H839_RS07235 H839_RS10615 H839_RS10615 H839_RS09480 H839_RS13565 dITP diphosphate molybdopterin- tyrosine-- H839_RS13960 2-deoxy- -D-ribose 1-phosphate acyl-carrier protein 3-hydroxytetradecanoyl]- [+ 4 isozymes] (S)-3- dethiobiotin thioredoxin pyridoxal kinase: pyridoxal kinase: 5'-methylthioadenosine pyruvate ω glycosyltransferase: 4-cis- OPC4-3- (2R,3S)-3- undecaprenylcistransferase: tyr α , mono- sn-glycerol acetyl-CoA a ribonucleoside hydroxydecanoyl- 2+ 2+ H839_RS17520 H839_RS17520 guanine methionine tRNA ligase: isocitrate dehydrogenase: pyruvate kinase: -D-glucosamine a peptidoglycanH839_RS14270 ser undecenoyl-CoA ketoacyl-CoA methylmalate Mo RS14915 Mo H839_RS05010 nucleosidase: phosphopentomutase: trans,octa-cis 3-phosphate diphosphate di-trans,octa-cis dinucleotide synthase: H839_RS14265 an L-tyrosyl- H839_RS01660 H839_RS08340 superpathway of pyrimidine dimer CoA biotin synthase: pyridoxine pyridoxamine H839_RS12970 H839_RS11915 -decaprenyl -undecaprenyl biosynthesis Tyr deoxyribonucleosides degradation (mycobacteria) H839_RS09655 thioredoxin lipoate biosynthesis H839_RS02865 [tRNA ] [+ 2 isozymes] 5'-phosphate 5'-phosphate Tyr diphosphate reductase: diphosphate protein B: S-ribosyl-L- a tRNA + + UDP and incorporation I L-homocysteine succinyl-CoA 2-oxoglutarate 2-deoxy-D-ribose 5-phosphate 2'-deoxycytidine Na RS02575 Na biotin H839_RS08780 guanylylH839_RS03025 S-adenosyl- homocysteine pyruvate pyrophosphate pyridoxal molybdenum thioredoxin pyridoxamine pyridoxamine L-methionine a (2R)-2-hydroxy 3-cis- 4-trans-3-oxo- 4-hydroxy- 3-hydroxyisovaleryl- trans-oct-2- a (3R)-3- NAD phosphorylation an octanoyl-[acp] cytidine 16-hydroxypalmitate glycerophosphoglycerol acetyl-CoA glutathione phosphatase: 5-phosphate 5-phosphate cofactor biosynthesis tetrahydrofolate salvage from deoxyribose- even numbered undecenoyl-CoA 2-nonenal CoA enoyl-CoA hydroxyicosanoyl- reductase: and dephosphorylation octanoyltransferase: folate polyglutamylation deaminase: dodecenoyl-CoA ITP H839_RS00580 oxidase: oxidase: pyridoxal kinase: 5,10-methenyltetrahydrofolate phosphate aldolase: long-chain fatty straight chain glycerophosphodiester beta-ketoadipyl beta-ketoadipyl glutathione enoyl-CoA enoyl-CoA [acp] Na + RS16525 Na + H839_RS15895 S-ribosylhomocysteinase: tryptophanyl- 2-oxoglutarate ferredoxin H839_RS12710 3-ketoacyl- di-trans,octa-cis H839_RS12380 met Trp H839_RS12760 thymidine acid--CoA ligase: CoA thiolase: CoA thiolase: transferase: hydratase: hydratase: nucleoside- + H839_RS10055 H839_RS10055 H839_RS17520 H839_RS14555 a tRNA oxidoreductase subunit thymine degradation 2,3,4-saturatedlong-chain fatty phosphodiesterase: ACP -undecaprenyl NAD a tetrahydrofolate S-adenosylmethionine a 5,10- tRNA synthetase: 4-aminobenzoate biosynthesis octanoyltransferase: alpha: H839_RS05245 H839_RS02680 fatty acid H839_RS07235 H839_RS10500 H839_RS10500 H839_RS10890 H839_RS09480 H839_RS09480 reductase: triphosphate phosphate synthetase: methenyltetrahydrofolate H839_RS03130 2'-deoxyuridine thymidine acid--CoA ligase: 4-hydroxy- a reduced a [lipoyl-carrierH839_RS17385 5,10-methylene- an L-tryptophanyl- thymine [+ 5 isozymes] enoyl-CoA enoyl-CoA diphosphatase: 6 D-glyceraldehyde 3-phosphate phosphorylase: H839_RS02680 glycerophosphodiester beta-ketoadipyl beta-ketoadipyl fabG + + protein] N - PLP H839_RS14500 [tRNA Trp ] acetaldehyde a (R)-2-hydroxy 2-nonenal- H839_RS13615 Na RS06900 Na chorismate thioredoxin heptaprenyl formate:tetrahydropteroylpolyglutamate folylpolyglutamate serine tetrahydrofolate dihydrothymine phosphodiesterase: CoA thiolase: CoA thiolase: hydratase: hydratase: inorganic octanoyl-L-lysine SAM trp deoA 16-hydroxypalmitoyl- [+ 5even isozymes] numbered glutathione [+ 5 isozymes] cyclohydrolase: dehydrogenase: acetaldehyde AMP diphosphate H839_RS10615 H839_RS10615 H839_RS10635 H839_RS10635 a 3-oxoicosanoyl- IMP 4-amino-4-deoxychorismate diphosphate geranyl ligase: H839_RS12225 synthase: hydroxymethyltransferase: Macromolecule Modification CoA AMP straight chain H839_RS06025 conjugate (E)-2- (S)-3- alkaline polyphosphate lipoyl synthase: H839_RS12225 H839_RS05775 dehydrogenase: uridine thymine diphosphate sn-glycerol 3-keto-5-cis- 2-trans- synthase: H839_RS18195 biosynthesis diphosphate H839_RS13470 H839_RS17135 10 acetyl-CoA [acp] kinase: ppnK an N - 2,3,4-saturated glycerol methylcrotonoyl- hydroxyoctanoyl- 2+ 2+ phosphatase: H839_RS15095 10 5,6-dihydrothymine H839_RS17585 phosphorylase: 3-phosphate tetradecenoyl-CoA nonenoyl-CoA Zn RS02170 Zn (2E,6E)-farnesyl biosynthesis an N - demethylmenaquinol- formyltetrahydrofolate CoA CoA 4-amino-4-deoxychorismate H839_RS00605 inorganic a [lipoyl-carrier tRNA processing H839_RS07610 fatty acyl CoA diphosphate formyltetrahydrofolate a 5,10- 8 biosynthesis I hydantoinase: thiamin salvage III heptaprenyl [+ 6 isozymes] protein]-N 6 - IPP a tetrahydrofolate phosphoribosylglycinamide threonyl-tRNA acetyl-CoA aminodeoxychorismate polyphosphate folylpolyglutamate methylenetetrahydrofolate H839_RS13285 diphosphate lipoyl-L-lysine farnesyl- formyltransferase: synthetase: lyase: H839_RS12545 kinase: ppnK 1,4-dihydroxy- a polycistronic 5-cis, 7-trans-3-oxo- a [protein] N-terminal- a (3R)-3- a 2,3,4- a (3R)-3- synthase: folylpolyglutamate a peptidoglycan a lipid II Zn 2+ RS12625 Zn 2+ synthase: diphosphate 2-naphthoate H839_RS00945 H839_RS09560 (R)-3-ureido- superpathway of 18-hydroxystearate phosphinothricin β saturated (3R)-3- hydroxyglutaryl- 4-amino-4-deoxychorismate thiamin H839_RS13470 synthase: 1,4-dihydroxy- tRNA precursor uracil 2-deoxy-α- tetradecadienoyl-CoA formyl-L-methionine hydroxydocosanoyl- -alanine IDP thiamine all-transH839_RS11370- synthase: threonyl-tRNA isobutanoate pyrimidine ribonucleosides long-chain fatty peptidoglycan beta-ketoadipyl peptide phosphinothricin [acp] hydroxyacyl-CoA [acp] methyl ester lyase: H839_RS18205 an N 10 - H839_RS13470 2-naphthoate a tetrahydrofolate thr D-ribose 1- 4-aminobutyrate enoyl-CoA 3-ketoacyl- heptaprenyl + H839_RS12210 synthase: β acid--CoA ligase: glycosyltransferase: acetyltransferase: 3-hydroxyacyl- nucleoside pyrophosphokinase: NADP geranyl octaprenyltransferase: -ureidopropionase: degradation phosphate CoA thiolase: deformylase: ACP diphosphate formyltetrahydrofolate a 5,10- cytidine H839_RS01655 ACP dehydratase: aminotransferase: hydratase: diphosphate D-serine D-serine 4-aminobenzoate H839_RS04635 H839_RS13885 an L-threonyl- H839_RS05765 H839_RS02680 H839_RS10500 H839_RS04595 H839_RS08755 reductase: RS17570 thiamin diphosphate methylenetetrahydrofolate H839_RS14610 phosphopentomutase: H839_RS06895 H839_RS09480 Thr cytidine deaminase: [+ 5 isozymes] peptidoglycan H839_RS16960 kinase: D-ala D-ala demethylmenaquinol-8 [tRNA ] a tRNA precursor H839_RS11915 beta-ketoadipyl peptide phosphinothricin fabG diphosphate Thr (R)-3-amino-2- 4-aminobutyrate enoyl-CoA H839_RS11365 a tRNA polynucleotide H839_RS12710 glycosyltransferase: CoA thiolase: deformylase: def acetyltransferase: a (2E)-docos- with a 5' methylpropanoate uridine 2-deoxy-D-ribose 18-hydroxystearoyl- an N-terminal L- aminotransferase: hydratase: [+ 5 isozymes] phosporylase: AMP diphosphate H839_RS14270 H839_RS10615 H839_RS14840 2-enoyl-[acp] a 3-oxoglutaryl- ITP extension and 5-phosphate CoA di-trans,octa-cis formate H839_RS06885 H839_RS10635 H839_RS05090 uridine 3-cis, 5-trans- methionyl-[protein] [acp] methyl ester predicted a long 3' trailer a tRNA precursor -undecaprenyl a peptidoglycan acetyl-CoA N-acetylphosphinothricin a cis-2-enoyl-CoA phosphorylase: dodecadienoyl-CoA 3-oxopropanoate ABC with a 5' deoxyribose- diphosphate H839_RS07610 met transporter met Amino Acid Biosynthesis seryl-tRNA extension and a phosphate ser RNase BN of L- synthetase: short 3' extension UTP and CTP dephosphorylation I uracil aldolase: exoribonuclease:ribonuclease PH: (15Z)- sn-glycero-3- 5-trans-3-oxo- 3-oxo-4- a (3R)-3- an L-1- methionine H839_RS17895 an L-seryl- H839_RS12760 a sulfurated 3-oxopropanoate a O- an aromatic superpathway of L- L-histidine biosynthesis L-glutamine H839_RS12000H839_RS13620 ribonuclease P: dihydropyrimidine tetracosenoate hydrogen cyanide dodecenoyl-CoA pregnene-20- hydroxypimeloyl- phosphatidyl- superpathway of L-lysine, L-threonine and L-methionine biosynthesis I L-alanine L-glutamate L-glutamate L-arginine biosynthesis I (via L-ornithine) [tRNA ser ] UTP phosphoethanolamine [sulfur carrier] sialoglycoprotein amino acid isoleucine biosynthesis I superpathway of L-methionine L-ornithine superpathway of L-serine H839_RS17810 dehydrogenase: long-chain fatty glycerophosphodiester methylmalonate- beta-ketoadipyl carboxyl-CoA [acp] methyl ester sn-glycerol predicted biosynthesis I biosynthesis III biosynthesis III biosynthesis II a tRNA ser rhodanese: aromatic amino acid 3-ketoacyl- biosynthesis (transsulfuration) biosynthesis II and glycine biosynthesis I H839_RS05775 D-glyceraldehyde O-sialoglycoprotein beta-ketoadipyl ABC a tRNA precursor acetaldehyde acid--CoA ligase: phosphodiesterase: H839_RS02250 semialdehyde CoA thiolase: ACP lipid kinase: PRPP oxaloacetate CTP synthetase: 3-phosphate endopeptidase: aminotransferase: CoA thiolase: met transporter met oxaloacetate 2-oxoglutarate 2-oxoglutarate glt 3-phospho- a tRNA with a short H839_RS02680 H839_RS06025 dehydrogenase: H839_RS10500 H839_RS01165 aspartate glt cys oxaloacetate 2-oxoglutarate H839_RS17260 rhodanese H839_RS03935 H839_RS10500 reductase: glutamate glutamate D-glycerate precursor with 3' extension 5,6-dihydrouracil acetaldehyde [+ 5 isozymes] glycerophosphodiester H839_RS05830 beta-ketoadipyl H839_RS00765 of L- aminotransferase: ATP glutamine aspartate cysteine glutamate D-3- domain protein: aromatic amino acid fabG 1-(3-sn- dehydrogenase: N-acetylglutamate a 5' extension UMP dehydrogenase: beta-ketoadipyl methionine phosphoribosyltransferase: synthetase: aminotransferase: desulfurase: dehydrogenase: aspartate dehydrogenase: phosphoglycerate (Z)-15- phosphodiesterase: H839_RS02255 [+ 2 isozymes] CoA thiolase: a peptide [+ 5 isozymes] phosphatidyl) H839_RS11180 synthase: prolyl-tRNA ribonuclease PH: CTP hydantoinase: H839_RS17585 AMP diphosphate aminotransferase: CoA thiolase: H839_RS15935 H839_RS05430 H839_RS11180 H839_RS11520 H839_RS11520 aminotransferase: H839_RS11520 nucleotidase: tetracosenoyl-CoA H839_RS07235 an unsulfurated NADH CO acetyl-CoA H839_RS10615 a 3-oxopimeloyl- -sn-glycerol pro RS17535 pro H839_RS10775 dehydrogenase: synthetase: thiocyanate 2 H839_RS14885 H839_RS10615 asp H839_RS03050 ribonuclease P: H839_RS13620 H839_RS13285 sn-glycerol [sulfur carrier] 3-trans- [acp] methyl ester ATP glutamine [+ 4 isozymes] glt glt H839_RS11180 glt H839_RS11595 H839_RS00785 H839_RS12610 acetyl-CoA ethanolamine acetyl-CoA an aromatic 3,22-dioxochol- 3-phosphate 3-phospho- H839_RS17810 3-phosphate decenoyl-CoA phosphoribosyltransferase: synthetase: asp ala N-acetyl-L- [+ 2 isozymes] 3-ureidopropanoate 2-oxo-acid 4-en-24-oyl-CoA aspartate kinase: hydroxypyruvate pro prolyl-tRNA H839_RS15945 H839_RS09290 asp glutamate gamma- Respiration CMP H839_RS05125 3-phosphoserine synthetase: uridine ala RS17635 ala gln aspartate kinase: glutamyl kinase: β-ureidopropionase: [+ 2 isozymes] 1-(5-phospho- acetylglutamate aminotransferase: H839_RS05030 an L-prolyl- nucleotidase: a 2-methyl RNase III mRNA a negatively a (3R,9Z)-3- dUDP H839_RS05125 aspartate kinase: H839_RS10680 H839_RS05765 18-hydroxyoleate oleate decanoyl-CoA acetyl-CoA β-D-ribosyl)-ATP kinase: Pro an uncharged 2-oxoisovalerate decarboxylation to isobutanoyl-CoA H839_RS12610 branched 2,3,4- processing acyl-carrier protein supercoiled DNA leu hydroxyhexadec- L-aspartyl- [+ 2 isozymes] H839_RS05125 H839_RS02595 [tRNA ] purine ribonucleosides degradation ribonucleotide- H839_RS03055 γ a tRNA Pro [+ 2 isozymes] long-chain fatty saturated fatty acid long-chain fatty substrate beta-ketoadipyl DNA 9-enoyl-[acp] phosphoribosyl-ATP [+ 2 isozymes] -L-glutamyl tRNA long-chain fatty ribonuclease III: leucine 3-ketoacyl- 4-phosphate 3-phospho- an [apo BCAA β-alanine acid--CoA ligase: acid--CoA ligase: CoA thiolase: malonyl CoA-ACP topoisomerase I: diphosphate gln RS17540 gln pyrophosphatase: N-acetylglutamyl- 5-phosphate cytidine acid--CoA ligase: H839_RS00060 dehydrogenase: ACP L-aspartyl-4-phosphate L-serine dehydrogenase H839_RS02680 H839_RS02680 H839_RS10615 transacylase: H839_RS04795 reductase aspartate- H839_RS15905 L-aspartyl- phosphate gamma- H839_RS02680 ribonuclease III: H839_RS10580 reductase: E2 protein] N 6 2-oxoisovalerate adenosine H839_RS04685 subunit beta: semialdehyde β 4-phosphate phosphoserine [+ 5 isozymes] [+ 5 isozymes] beta-ketoadipyl DNA fabG 1-(5-phospho- - aspartate- n-acetyl-gamma- glutamyl dehydrogenase: [+ 5 isozymes]a 2-methyl H839_RS04700RNase III leucine H839_RS02375 dehydrogenase: phosphatase: -lipoyl-L-lysine a single- CoA thiolase: topoisomerase III: D-ribosyl)-AMP aspartate- phosphate phenylalanyl- queuosine biosynthesis 18-hydroxyoleoyl- branched processing a malonyl-[acp] dehydrogenase: a (9Z)-3-[+ 5 isozymes] predicted semialdehyde glutamyl- 2-oxoisovalerate H839_RS04080 adenosine AMP diphosphate AMP diphosphate diphosphate AMP oleoyl-CoA stranded RNA [+ 4 isozymes] H839_RS05120 reductase: H839_RS17650 tRNA synthase CoA product mRNA H839_RS10500 H839_RS07220 ABC phosphoribosyl- dehydrogenase: semialdehyde phosphate dehydrogenase: [+ 7 isozymes] deaminase: 2,3,4-saturated 3-oxododecanoyl- H839_RS12145 oxohexadec- UDP gln gln proA subunit beta: pyrimidine deoxyribonucleotides a relaxed DNA 4-methyl-2- transporter L-aspartate- AMP H839_RS05120 dehydrogenase: reductase: ser preQ H839_RS17920 fatty acyl-CoA CoA 9-enoyl-[acp] 0 H839_RS04080 dephosphorylation of L-glutamine semialdehyde cyclohydrolase: H839_RS05120 H839_RS03045 H839_RS13820 oxopentanoate L-aspartate- L-glutamate-5- [+ 7 isozymes] nucleoside- H839_RS15905 superpathway of branched amino acid biosynthesis N-acetyl-L- phenylalanine- an [apo BCAA homoserine semialdehyde L-aspartate- semialdehyde serine phe an [apo BCAA dehydrogenase triphosphate xanthosine adenosine inosine guanosine a reduced 1-(5-phospho-β-D-ribosyl)- glutamate 5- -tRNA hydroxymethyltransferase: dehydrogenase 6 a 3-methyl- a (3R)-3- a (3R)-3- (S)-3- a (3R,7Z)-3- dehydrogenase: semialdehyde ornithine--oxo-acid preQ E2 protein] N -S-[2- diphosphatase: a nucleoside a [ThiI sulfur-carrier dCDP H O c-type 5-[(5-phosphoribosylamino) semialdehyde ligase: pheS an L-phenylalanyl- 1 E2 protein] N 6 7-hydroxylaurate branched 2,3,4- a ribonucleic acid hexanoyl-CoA acetyl-CoA hydroxybutanoyl- hydroxyhexacos- 2 H839_RS15045 pyruvate thr H839_RS17135 methylpropanoyl]dihydrolipoyl- H839_RS13615 cys hydroxyicosanoyl- hydroxyhexacosanoyl- cytochrome dihydrodipicolinate homoserine homoserine acetylornithine aminotransferase: Phe triphosphate protein]-L-cysteine ribonucleotide- RS17325 an oxidized methylideneamino]imidazole- hydrogen [tRNA ] tRNA-guanine -dihydrolipoyl- dCTP dCMP long-chain fatty saturated fatty acid cysteine beta-ketoadipyl [acp] [acp] CoA 7-enoyl-[acp] Phe L-lysine purine nucleoside purine nucleoside purine nucleoside purine nucleoside long-chain fatty DNA-directed 3-ketoacyl- enoyl-CoA 3-ketoacyl- 4-carboxamide synthase: dehydrogenase: acetolactate dehydrogenase: carbonate aminotransferase: rocD gly a tRNA L-lysine acid--CoA ligase: CoA thiolase: 3-hydroxyacyl- diphosphate O c-type L-homoserine transglycosylase: desulfurase: ACP 2 threonine phosphorylase: phosphorylase: phosphorylase: phosphorylase: acid--CoA ligase: RNA polymerase ACP dehydratase: ACP hydratase: reductase cytochrome 1-(5-phosphoribosyl) H839_RS15350 H839_RS15045 synthase: H839_RS15045 carbamoyl H839_RS03060 H839_RS13175 H839_RS02680 H839_RS10615 arg RS12070 arg dehydratase: L-ornithine dUTPase: H839_RS09615 H839_RS11910 H839_RS11910 H839_RS11910 H839_RS02680 subunit beta: H839_RS13245 reductase: H839_RS10635 reductase: subunit beta: homoserine -5-[(5- dihydrodipicolinate H839_RS01325 a 7-aminomethyl-7- [+ 5 isozymes] beta-ketoadipyl H839_RS16960 H839_RS07505 L-homoserine phosphate N-acetyl-L- superpathway of L-methionine H839_RS08130 purine nucleoside purine nucleoside purine nucleoside purine nucleoside [+ 5 isozymes] H839_RS00115 a [ThiI[+ sulfur-4 isozymes] fabG fabG kinase: synthase: [+ 2 isozymes] deazaguanosine 34 2-oxoisovalerate a 3-methyl- a (2E)-icos- enoyl-CoA H839_RS02375 phosphoribosylamino) synthase ornithine biosynthesis (by sulfhydrylation) 7-hydroxylauroyl- CoA thiolase: L-homoserine threonine [+ 3 isozymes] phosphorylase: phosphorylase: phosphorylase: phosphorylase: branched [+ 5 isozymes] ala carrier protein]-S- [+ 5 isozymes] hydratase: a (7Z)-3-[+ 5 isozymes] [+ 4 isozymes] H839_RS15035 methylideneamino] H839_RS05130 large subunit: methionyl-tRNA in tRNA dehydrogenase: AMP diphosphate diphosphate AMP H839_RS10500 2-enoyl-[acp] a 3-oxohexacosanoyl- (S)-2-acetolactate dehydratase: homoserine O- dUTP dUMP H839_RS11910 H839_RS09615 H839_RS09615 H839_RS09615 CoA 2,3,4-saturated a ribonucleic acid sulfanyl-L-cysteine oxohexacos- arg RS02490 arg imidazole-4- H839_RS03070 L-phenylalanine met S-adenosylmethionine H839_RS04080 3-oxooctanoyl- [acp] H839_RS09480 CDP O-phospho- H839_RS09545 succinyltransferase: oxaloacetate synthetase: fatty acyl-CoA carboxamide isomerase: (2S,4S)-4- biosynthesis I an L-methionyl- tRNA [+ 7 isozymes] CoA crotonyl-CoA 7-enoyl-[acp] L-homoserine homoserine O- homoserine ketol-acid H839_RS07370 [+ 3 isozymes] H839_RS18010 α-D-ribose- H839_RS15915 hydroxy-2,3,4,5- (2Z)-2-aminobut- aspartate [elongator ribosyltransferase: 5-hydroxy-CMP threonine succinyltransferase: kinase: reductoisomerase: 5-hydroxy-CTP 1-phosphate arg arg tetrahydrodipicolinate 2-enoate O-succinyl-L- carbamoyl elongator tRNA Met ] H839_RS13180 phosphoribulosylformimino- H839_RS07370 H839_RS15035 H839_RS13580 cys L-ornithine aminotransferase: chorismate synthase: phosphate tRNA Met a (3R)-3- a (3R,5Z)-3- RS03625 (2R)-2,3- homoserine H839_RS11180 chorismate an epoxyqueuosine 34 phosphopentomutase: a very-long- a CDP- sn-glycerol a (3R,6Z)-3- H839_RS14660 AICAR-P cys an acyl-[acyl- sn-glycerol butanoyl-CoA acetyl-CoA hydroxytetracosanoyl- D-threo-isocitrate hydroxytetracos- dihydroxy-3- mutase: in tRNA 2-oxoglutarate decarboxylation to succinyl-CoA H839_RS11915 chain fatty acid a pimeloyl-[acp] ala hydroxyoctadec- ornithine ornithine diacylglycerol 3-phosphate carrier protein] 3-phosphate GTP arg threonine O-phospho- methylbutanoate ornithine asp H839_RS11345 long-chain fatty CDP-diacylglycerol-- beta-ketoadipyl 6-enoyl-[acp] [acp] 3-ketoacyl- isocitrate 5-enoyl-[acp]3-ketoacyl- arg imidazole glycerol (S)-2,3,4,5- O-succinyl-L-homoserine cystathionine epoxyqueuosine D-ribose 5- 8-amino-7- glycerol-3- 3-hydroxyacyl- synthase: L-homoserine carbamoyltransferase: a [2-oxoglutarate acid--CoA ligase: glycerol-3-phosphate 3- CoA thiolase: dehydrogenase: diguanylate RS09040 tetrahydrodipicolinate dihydroxy-acid 2-iminobutanoate gamma-synthase: chorismate reductase: phosphate oxononanoate phosphate ACP ACP H839_RS15040 phosphate H839_RS03075 lysyl-tRNA dehydrogenase H839_RS05380 H839_RS10615 ACP dehydratase: H839_RS01660 threonine dehydratase: H839_RS03345 aspartate kinase: mutase: Lys phosphatidyltransferase: synthase: acyltransferase: reductase: reductase: cyclase: ornithine ornithine synthase: a tRNA H839_RS01985 6 2-oxoglutarate H839_RS16960 2,3,4,5- H839_RS05125 synthetase: E2 protein] N [+ 5 isozymes] H839_RS05210 beta-ketoadipyl isocitrate H839_RS00485 cystathionine synthase: H839_RS10675 H839_RS14305 34 H839_RS10860 H839_RS07540 a (2E,6Z)- fabG fabG predicted thr H839_RS15910 tetrahydropyridine- [+ 2 isozymes] sulfate H839_RS18235 a queuosine -lipoyl-L-lysine dehydrogenase: 1-(3-sn- a 1-acyl-sn gamma-synthase: H839_RS14660 [+ 2 isozymes] prephenate an L-lysyl- a very-long-chain 8-amino-7- CoA thiolase: octadecadienoyl- [+ 5 isozymes] dehydrogenase: [+ 5 isozymes] [+ 5 isozymes] ABC 2,6-carboxylate N- 3-methyl-2- in tRNA H839_RS03865 phosphatidyl) acyl-carrier protein acyl-carrier protein -glycerol 3- a (5Z)-3- 2+ 2+ imidazole L-citrulline [tRNA Lys ] 2-oxoglutarate Carbohydrate Degradation AMP diphosphate CMP oxononanoate H839_RS10500 a 3-oxotetracosanoyl- H839_RS13960 c-di-GMP Co Co H839_RS03345 threonine oxobutanoate sulfate heparin degradation fatty acyl-CoA -sn-glycerol phosphate [acp] oxotetracos- transporter threonine glycerol succinyltransferase: 2-oxobutanoate L-aspartyl- prephenate dehydrogenase: [+ 3 isozymes] D-mannose 3-oxohexanoyl- [acp] [+ 2 isozymes] synthase: L-cystathionine lys 3-phosphate oxalosuccinate 5-enoyl-[acp] of Co2+ dehydratase: phosphate H839_RS04025 argininosuccinate 4-phosphate adenylyltransferase: sat dehydratase: H839_RS03865 degradation CoA H839_RS15040 2-isopropylmalate branched-chain heparin H839_RS07505 synthase: hisH N-succinyl-2-amino- acetolactate cystathionine synthase: H839_RS13305 [+ 3 isozymes] synthase: amino acid aspartate- APS a [2-oxoglutarate a [2-oxoglutarate D-mannopyranose predicted threonine 6-ketopimelate synthase: β-lyase: H839_RS14070 2-oxo-3- L-cystathionine thr H839_RS13575 aminotransferase: semialdehyde dehydrogenase dehydrogenase 6-phosphate methylmalonate an N-acylated 3-oxo- OPC8-3- a (3R,11Z)-3- a (1->4)- ABC H839_RS01325 L-arginino- mannose-6- α-linolenate sn-glycerol 2+ 2+ dehydratase: AICAR D-erythro-imidazole- N-succinyldiaminopimelate H839_RS03350 dehydrogenase: adenylylsulfate phenylpropanoate histidyl-tRNA E2 protein] N 6 E2 protein] N 6 -S- 4-deoxy-2-O-sulfo- a stearoyl-[acp] aliphatic-L- hydroxyoctadec- α-D-glucan Co Co H839_RS13600 [+ 2 isozymes] his phosphate semialdehyde palmitoyl-CoA pyruvate dGTP 2'-deoxyadenosine hydroxyacyl-CoA transporter H839_RS09545 glycerol-phosphate aminotransferase: cystathionine succinate kinase: aromatic amino acid β-L-erythro-hex-4- 3-phosphate beta-ketoadipyl enoyl-CoA 11-enoyl-[acp] glycogen (2S)-2- H839_RS05120 synthetase: -dihydrolipoyl- succinyldihydrolipoyl- isomerase: methylmalonate- long-chain fatty glycerol-3- amino acidN-acyl-L- 3-ketoacyl- of Co2+ H839_RS03060 β-lyase: (S)-2-aceto-2- L-homocysteine argininosuccinate H839_RS01500 enopyranuronosyl- pyruvate kinase: branching (2Z)-2-aminobut- imidazoleglycerol- isopropylmalate aminotransferase: H839_RS13120 an L-histidyl- L-lysine L-lysine semialdehyde acid--CoA ligase: CoA thiolase: hydratase: hydroxybutanoate L-aspartate- H839_RS17630 phosphate amino acid H839_RS08340 deoxycytidine ACP 2-enoate N-succinyl-L,L-2,6- H839_RS03350 val lyase: H839_RS03935 His (1,4)-D-N- dehydrogenase: H839_RS05380 H839_RS10615 H839_RS09480 protein: phosphate isopropylmalate semialdehyde PAPS [tRNA ] Fermentation F6P acyltransferase: amidohydrolase: kinase: reductase: predicted diaminopimelate ketol-acid methionine methionine H839_RS14065 His sulfoglucosamine chitin degradation II H839_RS05830 [+ 2 isozymes] H839_RS14645 dehydratase: isomerase: aromatic amino acid a tRNA [+ 5 isozymes] H839_RS07540 H839_RS16535 beta-ketoadipyl phosphoenol H839_RS17905 enoyl-CoA fabG a (1,6)-α-D- ATP-driven L-homocysteine reductoisomerase: synthase: synthase: homoserine 6-O-sulfate 1-stearoyl- dGDP Co 2+ Co 2+ H839_RS15925 H839_RS13560 phosphoadenosine aminotransferase: 2-oxoglutarate glucose and glucose-1-phosphate degradation [+ 2 isozymes] an aliphatic CoA thiolase: pyruvate hydratase: [+ 5 isozymes] glucosyl-(1,4) transporter H839_RS13580 H839_RS02865 H839_RS02865 arg dehydrogenase: pyruvate fermentation to propanoate I iduronate hydrogen AMP diphosphate α-linolenoyl-CoA acyl-carrier protein sn-glycerol a carboxylate an (11Z)-3- phosphosulfate H839_RS14885 dehydrogenase: chitin H + NADH propanoyl-CoA L-amino acid H839_RS10500 dAMP H839_RS10635 α of Co2+ imidazole acetol- methionine methionine isopropylmalate H839_RS15045 sulfatase: α-D- carbonate 3-phosphate oxooctadec- - -glucan 2-iminobutanoate (R)-2,3-dihydroxy- reductase: H839_RS03865 OPC8-trans- phosphate synthase: synthase: isomerase: met H839_RS15840 myristoyl-CoA acetyl-CoA 11-enoyl-[acp] 3-methylpentanoate H839_RS01510 phe oxaloacetate [+ 4 isozymes] 4-deoxy-β-L- glucopyranose 2-enoyl-CoA L,L-diaminopimelate H839_RS02865 H839_RS02865 H839_RS13565 L-homoserine glycine-- histidinol-phosphate dihydroxy-acid gly erythro-hex-4- 1-phosphate aminotransferase: sulfite tRNA ligase: malate 2-isopropylmaleate dehydratase: enopyranuronosyl- a chitodextrin a (3R,6Z)-3- H839_RS11310 diaminopimelate met homoserine O- H839_RS17460 dehydrogenase: UDP-N-acetyl-α-D-muramoyl- an [amino group carrier protein]- 3-benzyl-3,6- an organic a [lipoyl-carrier OPC4-3- H839_RS10675 Gly D-alanyl-D-alanine pristanate Asn epimerase: acetyltransferase: a glycyl-[tRNA ] (1,4)-D-N- γ C-terminal-γ-(L-glutamate 5- dihydroxy-6- protein]-N 6 -[(R) hydroxyacyl-CoA hydroxyoctadec- tRNA asp 2-oxobutanoate isopropylmalate methylmalonyl-CoA H839_RS13955 Pentose Phosphate Pathways L-alanyl- -D-glutamyl-L-lysine glutathione hydroperoxide pyruvate dATP H839_RS15000 (S)-3-methyl-2- H839_RS07370 Gly sulfoglucosamine long-chain fatty semialdehyde-2-yl)-L-glutamate (hydroxymethyl) alkyl enoyl-CoA 6-enoyl-[acp] L-histidinol-phosphate isomerase: a tRNA carboxyltransferase: phosphoglucomutase: UDP-N-acetylmuramoyl- n-acetyl-gamma- -dihydrolipoyl]- 3-ketoacyl- aspartate- oxopentanoate 6-O-sulfate D-glucopyranose acid--CoA ligase: -diketopiperazine glutathione hydroperoxide pyruvate kinase: hydratase: acetolactate H839_RS13560 O-acetyl-L- (S)-methylmalonyl-CoAH839_RS12040 (S)-malate H839_RS16860 tripeptide--D-alanyl- glutamyl-phosphate L-lysine dihydrolipoamide ACP -tRNA meso-diaminopimelate pentose phosphate pathway (non-oxidative branch) beta-N- H839_RS02680 transferase: reductase: H839_RS08340 synthase: histidinol branched-chain homoserine hydrogen sulfide fumarate hydratase: D- alanine ligase: reductase: 3-benzyl-3,6 - dehydrogenase: H839_RS09480 reductase: ligase: isopropylmalate L-methionine salvage cycle I (bacteria and plants) acetylhexosaminidase: chitotriose phosphoglucomutase: quinoprotein H839_RS10890 [+ 2 isozymes] H839_RS01325 phosphatase: amino acid methylmalonyl- glucokinase: H839_RS00620 [+ 5 isozymes] H839_RS03045 H839_RS09310 H839_RS10560 enoyl-CoA fabG aspS isomerase: H839_RS00850 D-ribulose H839_RS02125 glucose an [amino group carrier protein]- bis(glutathione)- phosphoenol H839_RS11600 diaminopimelate aminotransferase: H839_RS10415 H839_RS12400 alkylhydroperoxidase: dADP a [lipoyl-carrier hydratase: an L-aspartyl- [+ 2 isozymes] L-tryptophan biosynthesis methionyl-tRNA CoA epimerase: fumarate hydratase: 5-phosphate N,6-O-disulfo- dehydrogenase: [+ 2 isozymes] C-terminal-γ-(5-phospho- 6-(hydroxymethyl) pyruvate [+ 2 isozymes] a (6Z)-3-[+ 5 isozymes] decarboxylase: H839_RS13565 O-acetylhomoserine UDP-N-acetyl-α-D-muramoyl-L-alanyl- AMP diphosphate pristanoyl-CoA 6 Asn histidinol H839_RS13600 met H839_RS12045 glucokinase: L-glutamyl)-L-glutamate -diketopiperazine H839_RS15180 protein]-N - H839_RS10635 [tRNA ] (S)-2-aceto-2- H839_RS11845 met aminocarboxypropyltransferase: synthetase: H839_RS01565 D-glucosamine N,N'- H839_RS08695 γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine OPC4-trans- oxooctadec- phosphatase: (2R,3S)-3- 2-oxoglutaramate H839_RS12500 lipoyl-L-lysine hydroxybutanoate L-arginine biosynthesis II (acetyl cycle) H839_RS18010 an L-methionyl- ribose 5- ribulose- diacetylchitobiose an alcohol 6-enoyl-[acp] H839_RS14245 gln chorismate isopropylmalate ile 2-oxo-4-methylthiobutanoate- H839_RS15205 (R)-methylmalonyl-CoA fumarate D-glucono- 2-enoyl-CoA ketol-acid lys [initiator tRNA Met ] phosphate phosphate 3- beta-N- D-glucopyranose 3-isopropylmalate glutamine aminotransferase: fumarate 1,5-lactone reductoisomerase: 2-oxoglutaramate N-acetylglutamyl- initiator tRNA Met isomerase: epimerase: acetylhexosaminidase: 6-phosphate histidinol anthranilate dehydrogenase: H839_RS03585 methylmalonyl- reductase: sdhA H839_RS13580 amidase: H839_RS03580 phosphate N-sulfo-D- N-acetyl-D- a [pyruvate dehydrogenase OPC6-3- a cis-delta11-3- synthase component S-adenosylmethionine L-homocysteine CoA mutase: H839_RS17145 H839_RS04630 H839_RS10415 lysine within a ribosomal an unfolded H839_RS13570 glucosamine an octanoyl-[acp] phytenate galactosamine E2 protein] N 6 - octanoyl-CoA acetyl-CoA a [protein] Ser/Thr hydroxyC30:1- (R)-2,3-dihydroxy- histidinol synthetase: H839_RS14500 H839_RS12095 N-acetyl-D- gcv protein H hydroxyacyl-CoA I: H839_RS11340 (2S)-2-isopropyl- 2-oxoglutarate long-chain fatty 6-phosphate dihydrolipoyl-L-lysine beta-ketoadipyl serine/threonine protein-L-alanine enoyl-CoA [acp] protein 3-methylpentanoate dehydrogenase: methionine methionine n-acetyl-gamma- D-ribose 5- D-xylulose glucosamine D-gluconate octanoyltransferase: N-acetylglucosamine- dihydrolipoamide alanine 3-ketoacyl- anthranilate synthase 3-oxosuccinate [+ 2 isozymes] acid--CoA ligase: CoA thiolase: protein kinase: hydratase: H839_RS15930 L-isoleucine synthase: synthase: glutamyl- phosphate 5-phosphate trehalose degradation H839_RS17385 6-phosphate dehydrogenase: acetyltransferase: ACP chaperonin: dihydroxy-acid component II: succinyl-CoA succinate H839_RS05380 H839_RS10615 H839_RS04620 H839_RS09480 biosynthesis IV 2-oxo-4-methylthiobutanoate SAM H839_RS02865 H839_RS02865 phosphate I (low osmolarity) octanoyltransferase: deacetylase: H839_RS00760 reductase: H839_RS00805 dehydratase: histidinal H839_RS18200 D-glucosamine H839_RS12135 S-adenosylmethionine reductase: transketolase: H839_RS12380 [+ 5 isozymes] H839_RS11725 beta-ketoadipyl [+ 6 isozymes] [+ 3 isozymes] enoyl-CoA fabG H839_RS10675 N-acetylglutamate acetylglutamate α,α-trehalose a [glycine-cleavage [+ 2 isozymes] a ribosomal propanoate decarboxylase proenzyme: met H839_RS03045 H839_RS05455 α D-galactosamine a [pyruvate dehydrogenase CoA thiolase: a [protein] (L-serine/L- hydratase: histidinol anthranilate 4-methyl-2- kinase: 2-O- -mannosyl-D- acyl-carrier protein complex H protein] acetate protein-N- [+ 5 isozymes] a protein (S)-3-methyl-2- H839_RS08840 synthase: 6-phosphate diphosphate AMP phytenoyl-CoA 6-phosphate 6 threonine) phosphate propanoate:CoA propionyl- glycerate degradation xylose degradation I 6 E2 protein] N -lipoyl-L-lysine H839_RS10500 H839_RS10635 a cis-delta11-3- oxopentanoate dehydrogenase: oxopentanoate H839_RS03050 H839_RS03055 N-acetyl-L- N -octanoyl-L-lysine 3-oxodecanoyl- acetyl-L-alanine OPC6-trans- ligase (AMP- S-adenosylmethionine N-acetyl-L- Aromatic Compound Biosynthesis CoA:succinate D-sedoheptulose D-glyceraldehyde oxo-C30:1-[acp] H839_RS15930 anthranilate branched-chain glt glutamate 5- 2-O-(6-phospho- trehalose-6- CoA 2-enoyl-CoA branched-chain forming): decarboxylase proenzyme: glutamate CoA transferase: 7-phosphate 3-phosphate phosphoribosyltransferase: trpD amino acid acetylornithinesemialdehyde α-D-mannosyl) phosphate D-xylopyranose amino acid H839_RS13915 gln his H839_RS14280 chorismate biosynthesis I H839_RS01630 -D-glycerate xylose isomerase: aminotransferase: aminotransferase: aminotransferase: transaldolase: alpha- hydrolase: [+ 6 isozymes] N-(5-phosphoribosyl)-anthranilate 2,3-dihydroxybenzoate H839_RS06135 a [glycerolipid]- 3-oxo- (2R,3S)-3- a cis-delta13-3- H839_RS13600 H839_RS13600 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one dAdoMet H839_RS03060 H839_RS17240 mannosidase: H839_RS07950 N 6 -dimethylallyladenosine 37 a sulfurated a double-stranded propanoyl-CoA carbamoyl D-erythrose biosynthesis decanoate (5Z,8Z,11Z,14Z,17Z) coenzyme A L-canavanine hydroxyC32:1- lys H839_RS16760 xylose isomerase: [sulfur carrier] 2'-deoxyadenosine UTP myristoyl-CoA oligonucleotide isopropylmalate N-(5'-phosphoribosyl) phosphate in tRNA beta-ketoadipyl arginase: isopropylmalate putrescine N-acetylglutamate 4-phosphate D-glycerate β-D-glucose H839_RS14665 melibiose degradation dimethylallyladenosine long-chain fatty -icosapentaenoate long-chain fatty oligoribonuclease: [acp] 3-ketoacyl- ile 2-oxoacid anthranilate isomerase: leu 2-hydroxy-3-keto-5- synthase chorismate D-erythrose D-glucopyranose deoxycytidine amino acid synthase: F6P D-xylulose acid--CoA ligase: CoA thiolase: H839_RS08455 H839_RS00425 isomerase: ACP ferredoxin methylthiopentenyl- spermidine synthase: isochorismate 4-phosphate 6-phosphate tRNA acid--CoA ligase: kinase: H839_RS11325 large subunit: 3-deoxy- glycerate kinase: H839_RS02680 H839_RS10615 oligoribonuclease: H839_RS13565 racemase: L-citrulline biosynthesis H839_RS08845 H839_RS03050 glucokinase: methylthiotransferase: H839_RS05380 H839_RS17905 arginase: reductase: oxidoreductase: 1-(o-carboxyphenylamino)-1'- 1- phosphate H839_RS03070 synthase: transketolase: xylulokinase: melibiose H839_RS05695 D-arabino- H839_RS17640 6 [+ 5 isozymes] beta-ketoadipyl H839_RS14025 H839_RS01470 isopropylmalate fabG H839_RS05250 phosphatase: mtnX [+ 2 isozymes] spermidine N-acetyl-L- H839_RS14605 H839_RS12400 alpha-galactosidase: H839_RS05255 2-methylthio-N - [+ 5 isozymes] UDP dAMP deoxyribulose 5'-phosphate [+ 3 isozymes] heptulosonate- H839_RS05455 H839_RS06775 an unsulfurated icosapentaenoyl- CoA thiolase: a nucleoside 5'- isomerase: ornithine isochorismate 2-phospho- glucokinase: H839_RS06080 met 5'-deoxyadenosine dimethylallyladenosine 37 a glycerolipid urea L-canaline [+ 5 isozymes] D-lysine indole-3-glycerol gln 7-phosphate D-glyceraldehyde D-xylulose [sulfur carrier] diphosphate AMP decanoyl-CoA CoA H839_RS10500 monophosphate H839_RS13560 a cis-delta13-3- 2-oxobutanoate carbamoyl L-ornithine D-glycerate H839_RS12500 alpha-galactosidase: in tRNA L-proline biosynthesis III phosphate synthase: 2-hydroxy-5-(methylthio)-3- S-methyl-5'-thioadenosine 3-dehydroquinate 3-phosphate 5-phosphate (2S)-2- oxo-C32:1-[acp] phosphate isochorismatase: D-glucopyranose H839_RS11065 acetyl-CoA lauroyl-CoA acetolactate H839_RS11330 GMP synthase: oxopent-1-enyl 1-phosphate synthase: isopropylmalate 5'-methylthioadenosine H839_RS07195 6-phosphate D-galactopyranose D-glucopyranose synthase: H839_RS00875 H839_RS11350 (1S,2R)-1-C-(indol-3- nucleosidase: (2S,3S)-2,3- glt H839_RS01325 [+ 6 isozymes] 2,3-diketo-5- yl)glycerol 3-phosphate H839_RS12970 a [formate C α ω 3D-(3,5/4)- N-acetylmuramoyl- a cis-delta15-3- an oxidized methylthiopentyl-1- ornithine L-alanine 3-dehydroquinate dihydroxy-2,3- acetoin degradation a reduced , -9Z- sn-glycerol β [+ 2 isozymes] trihydroxycyclohexane- -isomaltose hydroxyC34:1- nitroaromatic gamma- phosphate enolase: mtnW biosynthesis I dihydrobenzoate SAM acetyltransferase]- octadecenedioate 2'-deoxyguanosine UTP L-alaninate phe 3-phosphate tryptophan synthase glt carbamoyltransferase: flavodoxin N-acetylmuramoyl- oligo-1,6- (S)-2-aceto-2- 3-dehydroquinate glycine long-chain fatty 1,2-dione glycerol-3- [acp] 3-ketoacyl- compound glutamyl kinase: subunit beta: H839_RS03075 3-methyl-2- coenzyme A acetoin pyruvate formate 3D-(3,5/4)- deoxycytidine aspartate NAD(P)H hydroxybutanoate L-proline dehydratase: acid--CoA ligase: L-alanine phosphate glucosidase: H839_RS10680 H839_RS06365 gamma- acetoin lyase-activating trihydroxycyclohexane- kinase: aminotransferase: ACP biosynthesis I oxobutanoatebranched-chain H839_RS12310 H839_RS05380 amidase: H839_RS02405 nitroreductase: 2-aceto-2-hydroxy- glutamyl kinase: protein: 1,2-dione hydrolase: acyltransferase: reductase: γ-L-glutamyl [+ 2 isozymes] 5-(methylthio)-2,3-dioxopentyl 1-phosphate S-methyl-5-thio-D-ribose 2,3- dehydrogenase: H839_RS17905 H839_RS00330 H839_RS11180 H839_RS03800 butanoate amino acid [+ 5 isozymes] 1-C16:0-α,ωH839_RS07540- oligo-1,6- fabG a reduced 5-phosphate pro H839_RS10680 methylthioribose 3-dehydroshikimate dihydroxybenzoate H839_RS14285 H839_RS17580 a [formate C ω H839_RS06950 UDP dGMP [+ 2 isozymes] isomeroreductase: indole ser glt aminotransferase: a flavodoxin -carboxy- 5-deoxy-D- [+ 2 isozymes] 2-oxo-3- glucosidase: γ kinase: H839_RS04285 acetaldehyde acetyl-CoA met 5'-deoxyadenosine acetyltransferase]- dicarboxyl-2- [+ 5 isozymes] nitroaromatic H839_RS13580 -L-glutamyl gamma- L-citrulline H839_RS13600 semiquinone AMP diphosphate (9Z)-octadec- glucuronate N-acetyl-D- phenylpropanoate H839_RS03520 a cis-delta15-3- L-ornithine proline methylthioribulose- shikimate shikimate glycin -2-yl radical ala lysophosphatidate compound gamma- 5-phosphate methylthioribose glutamyl kinase: 9-enoyl-CoA muramate oxo-C34:1-[acp] (R)-2,3-dihydroxy- dehydrogenase: 1-phosphate val dehydrogenase: dehydrogenase: D-glucopyranose glutamyl tryptophan synthase kinase: mtnK H839_RS10680 argininosuccinate Amine and Polyamine Degradation 3-methylpentanoate H839_RS15255 dehydratase: mtnB γ-L-glutamyl H839_RS12885 H839_RS12885 phosphate ornithine--oxo-acid subunit beta: gamma- synthase: dihydroxy-acid 5-phosphate reductase: aminotransferase: H839_RS06365 (S)-1-pyrroline- glutamyl H839_RS14070 shikimate 2-methoxy-6-all trans- dehydratase: 4-hydroxyphenylpyruvate allantoin degradation an [amino group carrier protein]-C- a guanine 46 a (3R,11Z)-3- a (3R)-3- a cis-delta19-3- 5-carboxylate gamma- N-acetylglucosamine 4-aminobutanoate ethanolamine sn-glycerol linoleate a D-hexose proA rocD tryptophan synthase phosphate L-arginino- biosynthesis to ureidoglycolate II urea degradation II a myristoyl-[acp] γ pimeloyl-CoA ala decaprenyl-2-methoxy- hydroxyoctadec- hydroxydocosanoyl- hydroxyC38:1- H839_RS10675 5-methylthioribulose 1-phosphate 5-MTR-1-P degradation I degradation III 3-phosphate terminal- -(L-ornithyl)-L-glutamate in tRNA glucokinase: subunit beta: reductase: glutamyl succinate shikimate kinase: (ammonia producing) utilization long-chain fatty 1,4-benzoquinol 11-enoyl-[acp] [acp] [acp] (S)-3-methyl-2- ala glycerol-3- acetylornithine 8-amino-7- ubiquinone tRNA (guanine-N7)- 3-ketoacyl- 3-ketoacyl- H839_RS11320 proA phosphate argininosuccinate H839_RS10715 N-acetyl-D- acid--CoA ligase: 3-hydroxyacyl- H839_RS12400 L-glutamate-5- tyr 4-aminobutanoate urea phosphate aminotransferase: oxononanoate biosynthesis methyltransferase: ACP ACP oxopentanoate reductase: (S)-(+)-allantoin glucosamine ethanolamine H839_RS02680 ACP dehydratase: glucokinase: semialdehyde lyase: alanine shikimate 3- 4-aminobutyrate urease subunit acyltransferase: H839_RS03060 synthase: methyltransferase H839_RS14370 reductase: reductase: aromatic amino acid allantoinase: ethanolamine 7 L-arginine branched-chain arg proA H839_RS14065 6-phosphateN-acetylglucosamine- [+ 5 isozymes] an [amino group carrier protein]- an N - H839_RS16960 H839_RS12500 L-glutamate-5- racemase: phosphate aminotransferase: aminotransferase: ammonia-lyase: gamma: H839_RS07540 H839_RS10860 UbiE: a (2E,11Z)- fabG fabG degradation I amino acid trp methylthioribose-1- H839_RS05780 6-phosphate C-terminal-γ-(L-glutamate 5- 8-amino-7- methylguanine 46 D-hexose 6- semialdehyde L-glutamate-5- H839_RS00650 H839_RS14885 H839_RS06895 H839_RS06810 1-myristoylglycerol coenzyme A H839_RS11375 octadeca-2,11- [+ 5 isozymes] [+ 5 isozymes] (arginase pathway) aminotransferase: 3-phosphoshikimate 1- allantoate H839_RS10535 acyl-carrier protein AMP diphosphate linoleoyl-CoA 6-methoxy-3-methyl- a 3- phosphate uracil degradation phosphate isomerase: mtnA semialdehyde arg deacetylase: [+ 2 isozymes] 3-phosphate semialdehyde-2-yl)-L-glutamate oxononanoate in tRNA dienoyl-[acp] a cis-delta19-3- H839_RS13600 arginase: amino acid carboxyvinyltransferase: aromatic amino acid 4-aminobutyrate ethanolamine 2-all-trans-decaprenyl- oxodocosanoyl- (S)-1-pyrroline- I (reductive) D-glucosamineH839_RS11725 ammonium oxo-C38:1-[acp] arg ornithine--oxo-acid H839_RS00425 racemase: H839_RS11300 aminotransferase: allantoate aminotransferase: ammonia-lyase: 1,4-benzoquinol [acp] 6-phosphate 5-carboxylate arginase: uracil aminotransferase: H839_RS05695 5-enolpyruvyl- H839_RS03935 amidohydrolase: H839_RS06885 ile arginase: succinate H839_RS10540 pyrroline-5- H839_RS00425 dihydropyrimidine rocD shikimate 3- 4-hydroxyphenylpyruvate H839_RS08600 acetaldehyde L-ornithine degradation H839_RS01470 semialdehyde a (3R,7Z,10Z,13Z,16Z (25R)-3α,7α,12α- a (3R)-3- a cis-delta21-3- carboxylate dehydrogenase: (S)-1-pyrroline- D-ala phosphate 5-(2-hydroxyethyl) an aryl dialkyl an insertion sequence a nucleoside arginase: L-cysteine I (L-proline biosynthesis) allantoate a cis- sn-glycerol octanoate trihydroxy-5β- hydroxydocosanoyl- hydroxyC40:1- H839_RS05775 5-carboxylate chorismate succinate- -4-methylthiazole ,19Z)-3-hydroxydocosa- element IS30 reductase: H839_RS01470 biosynthesis I amidohydrolase: α-D-glucosamine vaccenoyl-[acp] 3-phosphate phosphate cholestanoyl-CoA diphosphate semialdehyde long-chain fatty 7,10,13,16,19- transposase: [acp] [acp] 3-ketoacyl- nucleoside H839_RS11990 L-ornithine L-ornithine pyrroline-5- synthase: H839_RS16540 glycerol-3- phosphotriesterase: alpha-methylacyl- 3-ketoacyl- 5,6-dihydrouracil L-ornithine 6-phosphate acid--CoA ligase: hydroxyethylthiazole pentaenoyl-[acp] diphosphate carboxylate H839_RS11355 dehydrogenase: phosphate H839_RS05685 3-ketoacyl-ACP H839_RS00835 CoA racemase: ACP ACP ser ornithine glucosamine- H839_RS02680 kinase: H839_RS09985 kinase: pro ornithine--oxo-acid ornithine reductase: S-ureidoglycine gabD acyltransferase: phosphotriesterase: reductase: fabG [+ 15 isozymes] H839_RS05390 reductase: reductase: serine hydantoinase: cyclodeaminase: chorismate 6-phosphate [+ 5 isozymes] 4-methyl-5-(2- an insertion α α α aminotransferase: carbamoyltransferase: H839_RS11990 H839_RS075401-cis- H839_RS10000 [+ 5 isozymes] (25S)-3 ,7 ,12 - fabG fabG H839_RS11365 acetyltransferase: H839_RS13285 H839_RS01640 deaminase: succinate phosphonooxyethyl) a dialkyl a (7Z,10Z,13Z,16Z,19Z)-3- sequence IS30 with β a nucleoside rocD H839_RS03075 acyl-carrier protein vaccenoylglycerol- a phenol trihydroxy-5 - a 3- [+ 5 isozymes] [+ 5 isozymes] H839_RS00050 ornithine H839_RS11720 diphosphate AMP octanoyl-CoA thiazole phosphate oxodocosa-7,10,13,16,19- integrated transposon cholestanoyl-CoA a cis-delta21-3- triphosphate L-glutamate-5- 3-ureidopropanoate pro 3-phosphate oxodocosanoyl- O-acetyl-L-serine cyclodeaminase: L-citrulline pentaenoyl-[acp] oxo-C40:1-[acp] semialdehyde F6P Amino Acid Degradation [acp] H839_RS03420 S-ureidoglycolate cysteine β-ureidopropionase: 1-pyrroline-5- pro synthase: H839_RS05765 carboxylate L-valine degradation I a [2-oxoglutarate- a [protein]- an organic P1,P4-bis(5'- (3R,5S)-1- a cis-delta17-3- H839_RS18190 arginine, ornithine and proline interconversion NADH menadione H + acetyl-CoA propanoyl-CoA an unsulfurated uroporphyrinogen-III a phosphate dehydrogenase: dehydrogenase a sulfurated L-cysteine hydroperoxide cys guanosyl) pyrroline-3- hydroxyC36:1- β-alanine SAM [sulfur carrier] monoester E2 protein] N 6 - NADH:ubiquinone acetyl-CoA peroxiredoxin: uroporphyrin-III tetraphosphate [acp] H839_RS01000 Nucleoside and Nucleotide Biosynthesis [sulfur carrier] cysteine bis(5'-nucleosyl)- hydroxy-5- 3-ketoacyl- alkaline cys val oxidoreductase subunit acetyltransferase: H839_RS01845 methyltransferase: L-citrulline octanoyl-L-lysine lipoyl synthase: desulfurase: tetraphosphatase: carboxylatepyrroline-5- ACP phosphatase: glt H839_RS15095 H: H839_RS17055 H839_RS05405 peroxiredoxin: H839_RS13245 H839_RS07340 H839_RS03245 carboxylate H839_RS00605 superpathway of purine nucleotides de novo biosynthesis II branched-chain a [2-oxoglutarate reductase: superpathway of purine nucleotides de novo biosynthesis I superpathway of pyrimidine superpathway of guanosine adenine and adenine salvage an unsulfurated dehydrogenase NADH dehydrogenase: [+ 6 isozymes] H839_RS07545 [+ 4 isozymes] [+ 3 isozymes] reductase: fabG [+ 6 isozymes] amino acid 5'-deoxyadenosine met an intra- GMP GTP deoxyribonucleotides de novo biosynthesis nucleotides de novo biosynthesis I ornithine 6 H839_RS17060 β-ketovaleryl-CoA an alcohol a sulfurated precorrin-2 H839_RS11990 adenosine salvage III aminotransferase: [sulfur carrier] E2 protein] N protein disulfide ala trans-4-hydroxy- [+ 5 isozymes] an alcohol PRPP carbamoyltransferase: + [sulfur carrier] a cis-delta17-3- PRPP H839_RS13600 -lipoyl-L-lysine menadiol NAD L-proline hydrogen H839_RS03075 oxo-C36:1-[acp] gln IMP adenine 3-methyl-2- amidophosphoribosyltransferase: carbonate adenine purine nucleoside H839_RS00935 amidophosphoribosyltransferase: oxobutanoate carbamoyl carbamoyl phosphorylase: (4Z)-2- β H839_RS00935 inosine-5- 2-oxoisovalerate phosphate L-ornithine a [pyruvate a DNA containing a (7Z)-3-oxo- 5-phospho- - gly phosphate adenine adenine sn-glycerol an oxidized a kanamycin sn-glycerol histidinol monophosphate H839_RS11910 dehydrogenase a sulfurated a palmitoyl-[acp] a cyclobutane + hydroxyhepta- hexadec-7- D-ribosylamine dehydrogenase: SAM NADPH H a mercapturate 3-phosphate 5-phospho-β- synthase dehydrogenase: deaminase: phosphoribosyltransferase: 6 3-phosphate pyrimidine dimer flavodoxin aminoglycoside 2,4-dienedioate gly purine nucleoside H839_RS04080 E2 protein] N - [sulfur carrier] glycerol-3- ferredoxin-NADP N-acyl-L- 2-hydroxyhepta- enoyl-[acp]3-oxoacyl-ACP glycerol-3- histidinol D-ribosylamine large subunit: H839_RS04250 H839_RS00965 H839_RS13140 amino acid ornithine--oxo-acid deoxyribodipyrimidine phosphotransferase: Fatty Acid and Lipid Biosynthesis phosphoribosylamine- phosphorylase: [+ 4 isozymes] octanoyl-L-lysine lipoyl synthase: phosphate reductase: amino acid 2,4-diene-1,7- reductase: phosphate dehydrogenase: H839_RS03070 racemase: aminotransferase: photolyase: H839_RS03920 -glycine ligase: inosine-5- H839_RS09615 H839_RS15095 acyltransferase: H839_RS14985 amidohydrolase: dioate isomerase: H839_RS03890 acyltransferase: H839_RS15930 CO H839_RS05695 rocD a [pyruvate H839_RS15520 phosphoribosylamine- [+ 3 isozymes] adenosine isobutanoyl-CoA 2 a reduced [+ 2 isozymes] H839_RS07540 palmitate biosynthesis II (bacteria and plants) H839_RS00955 monophosphate an unsulfurated dehydrogenase H839_RS07540 NADP + H839_RS16535 H839_RS15340 a (3R,7Z)-3-[+ 3 isozymes] 1-[18- fatty acid elongation -- saturated -glycine ligase: hypoxanthine AMP 5'-deoxyadenosine met two adjacent pyrimidine a kanamycin dehydrogenase: 6 1-palmitoylglycerol flavodoxin an L-cysteine- (4Z)-2-oxohept- his carbamoyl asp adenine and isobutyryl- [sulfur carrier] E2 protein] N acyl-carrier protein nucleosides in DNA acetate 3'-phosphate hydroxy-hexadec- hydroxyoleyl]- H839_RS00955 adenosine ornithine L-glutamate-5- 3-phosphate S-conjugate 4-enedioate phosphate H839_RS17875 adenosine salvage I CoA:FAD D-ornithine -lipoyl-L-lysine 7-enoyl-[acp] 2-lyso- an acetoacetyl-[acp] GAR deaminase: xanthine semialdehyde oxidoreductase: cyclodeaminase: phosphatidate an acetoacetyl-[acp] H839_RS17920 phosphoribosyltransferase: phosphoribosylglycinamide GAR aspartate XMP H839_RS09505 H839_RS01640 3-ketoacyl- H839_RS09760 formyltransferase: adenosine ornithine carbamoyltransferase 3-benzyl-3,6 - a (3R)-3- a (3R,5Z)-3- ACP phosphoribosylglycinamide inosine hypoxanthine purine nucleoside methylacrylyl-CoA undecaprenyl-diphospho-N a double- a [protein]- H839_RS00945 catalytic subunit: cyclodeaminase: γ α stachyose an N-modified 5-aminolevulinate hydantoin reductase: formyltransferase: GMP synthase: phosphoribosyltransferase: phosphorylase: (2R,4S)-2, 4- (S)-1-pyrroline- -acetylmuramoyl-L-alanyl- - UDP-N-acetyl- -D-glucosamine bis(glutathione)- hydroxyhexacosanoyl- hydroxy-tetradec- helix DNA L-histidine H839_RS04515 H839_RS03420 alpha-galactosidase: aminoacyl-[tRNA] DNA/RNA fabG FGAR H839_RS00945 H839_RS00875 purine nucleoside H839_RS18170 H839_RS11910 enoyl-CoA diaminopentanoate 5-carboxylate D-glutamyl-L-lysyl- D-alanine UDP-diphospho- 6-(hydroxymethyl) peptidyl-tRNA [acp] delta- 5-enoyl-[acp]3-oxoacyl-ACP histidine kinase: gamma-glutamyl H839_RS06080 3-hydroxyacyl- hydantoinase: helicase: [+ 5 isozymes] phosphorylase: hydratase: muramoylpentapeptide beta-N- -diketopiperazine hydrolase: aminolevulinic reductase: H839_RS00480 a 3-oxoacyl-[acp] phosphoribosylformylglycinamidine FGAR purine nucleoside pyrroline-5- cyclotransferase: alpha-galactosidase: ACP dehydratase: H839_RS13285 H839_RS10820 a (3R)-3- N-carbamoyl- H839_RS11910 IMP H839_RS09480 acetylglucosaminyltransferase: H839_RS18085 acid dehydratase: H839_RS03890 [+ 26 isozymes] synthase: H839_RS00930 GMP phosphorylase: carboxylate 3-benzyl-3,6H839_RS09300 - H839_RS11065 H839_RS16960 hydroxybutanoyl- L-aspartate enoyl-CoA H839_RS00595 an N-modified an uncharged H839_RS13500 DNA helicase: a [protein]- phosphoribosylformylglycinamidine purine nucleoside H839_RS09615 reductase: ditrans,octacis-undecaprenyldiphospho- bis(cysteinylglycine) a (5Z)-3-oxo-[+ 3 isozymes] [acp] [+ 3 isozymes] hydratase: 5-oxo-L-proline α-D-galactose raffinose amino acid tRNA a (2E)-hexacos- porphobilinogen N-carbamoylglycine H839_RS17705 N-phospho- synthase: H839_RS00930 phosphorylase: adenine 2-amino-4- H839_RS11990 UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- - 6-(hydroxymethyl) tetradec-5- an unwound 3-hydroxyacyl- dihydroorotase: guanylate kinase: 2-enoyl-[acp] L-histidine 3-ketoacyl-ACP FGAM [+ 3 isozymes] H839_RS09615 H839_RS10635 L-isoleucine degradation I oxopentanoate L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine -diketopiperazine enoyl-[acp] double- ACP dehydratase: H839_RS04520 H839_RS04575 reductase: adenine (S)-3-hydroxy- stranded DNA H839_RS16960 FGAM pro H839_RS03785 phosphoribosylaminoimidazole (S)-dihydroorotate hypoxanthine phosphoribosyltransferase: isobutanoyl-CoA a (2E)-but- β-ketoacyl- synthetase: H839_RS00940 H839_RS13140 ile [+ 5 isozymes] GDP 3-hydroxyisobutyryl- amino acid a (3R)-3- a (9Z)-3-oxo- ACP synthase: phosphoribosylaminoimidazole dihydroorotate branched-chain amino decaprenyl-diphospho-N- UDP-N-acetyl- (2R)-phospho- 5-deoxy-D- a supercoiled 2-enoyl-[acp] xanthine CoA hydrolase: racemase: α ethylnitronate raffinose an acyl phosphate a nitrile acid aminotransferase: D-ala acetylmuramoyl-pentapeptide -D-glucosamine 3-sulfolactate hydroxytetracosanoyl- glucuronate octadec-9- duplex DNA H839_RS03110 a (3R)-3- AIR synthetase: H839_RS00940 dehydrogenase: phosphoribosyltransferase: AMP H839_RS10635 H839_RS05695 alpha-galactosidase: crotonyl-[acyl- a 2,3,4-saturated UDP-diphospho- 2-nitropropane 2-phosphosulfolactate [acp] enoyl-[acp]3-oxoacyl-ACP ATP-dependent nitrilase: hydroxyacyl-[acyl- H839_RS04540 H839_RS09760 H839_RS13600 acylphosphatase: 5-deoxyglucuronate carrier-protein] fatty acyl-[acp] 5 (S)-3-hydroxy- muramoylpentapeptide beta-N- dioxygenase: H839_RS06080 3-hydroxyacyl- DNA helicase H839_RS10470 carrier protein] N -carboxyaminoimidazole AIR nucleoside ribonucleotide- (S)-3-methyl-2-oxopentanoate phosphatase: isomerase: reductase: 3-hydroxyacyl- xanthine and D-proline acetylglucosaminyltransferase: alpha-galactosidase: ACP dehydratase: H839_RS07470 reductase: ribonucleotide synthetase: orotate PRPP diphosphate diphosphate hypoxanthine isobutanoate H839_RS04120 H839_RS03925 H839_RS06960 H839_RS03890 PcrA: nitrilase: ACP dehydratase: phosphoribosyltransferase: xanthosine salvage 3-methyl-2- H839_RS00595 H839_RS11065 H839_RS16960 [+ 2 isozymes] H839_RS03255 H839_RS00905 kinase: reductase 3-hydroxyisobutyrate [+ 2 isozymes] 2-deoxy-5- [+ 3 isozymes] H839_RS00985 H839_RS16690 H839_RS16960 phosphoribosylaminoimidazole L-arginine decaprenyl-pyrophosphoryl- [unspecified (2R)-3-sulfolactate a (3R,9Z)-3- orotate H839_RS11365 subunit alpha: H839_RS18170 dehydrogenase: oxopentanoate sucrose α-D-galactose a (2E)-tetracos- a carboxylate dehydro-D- [+ 5 isozymes] a carboxylate carboxylase: H839_RS00905 degradation VI UDP (N-acetylglucosamine)-N- degradation nitrite acetaldehyde hydroxy-octadec- a single a butanoyl-[acp] N5-CAIR phosphoribosyltransferase: H839_RS12375 H839_RS09865 dehydrogenase: 2-enoyl-[acp] gluconate xanthosine (arginase 2 pathway) acetylmuramyl-(pentapeptide) products] 9-enoyl-[acp] stranded DNA H839_RS04550 IMP (S)- H839_RS04090 β-ketohexanoyl- N5-carboxyaminoimidazole [+ 4 isozymes] CAIR asp purine nucleoside methylmalonate- 5-aminopentanoate enoyl-ACP ribonucleotide mutase: GTP 2-methylbutanoyl-CoA arg [acp] synthase: orotidine 5'- phosphorylase: semialdehyde H839_RS00900 superpathway of pyrimidine deoxyribonucleoside salvage arginase: a (3R,7Z)-3- H839_RS03110 reductase: a trans-2- phosphate H839_RS09615 2-amino-6-[1-hydroxyethyl]- phosphoenol a [PTS enzyme a single a [protein] (L-serine/L- betaine aldehyde chloroacetate S-2-methylbutryl- hydroxytetradec- L-threonine 3- a 2,3,4-saturated H839_RS01730 enoyl-[acyl- phosphoribosylaminoimidazole- dGDP H839_RS00425 7-methyl-7,8-dihydropterin pyruvate I]-L-histidine 4'-phosphopantetheine ATP stranded DNA ATP H O threonine) phosphate a 3-oxohexanoyl- 2'-deoxycytidine purine nucleoside 4-aminobutyrate methylmalonate- 2 O-phosphate fatty acyl-[acp] CAIR succinocarboxamide orotidine 5'- CoA:FAD arginase: 2-amino-4-hydroxy-6- phosphoenolpyruvate- betaine-aldehyde 7-enoyl-[acp]3-oxoacyl-ACP haloacid [acp] enoyl-ACP carrier protein] phosphorylase: aminotransferase, semialdehyde endonuclease IV: ATPase: protein threonine- synthase: H839_RS00915 phosphate nucleoside oxidoreductase: H839_RS01470 hydroxymethyldihydropteridine protein phosphopantetheine dehydrogenase: reductase: dehalogenase: reductase: phosphoribosylaminoimidazole- cytidine deaminase: deoxycytidine kinase: H839_RS11910 mitochondrial: dehydrogenase: H839_RS04560 phosphatase: phosphate decarboxylase: H839_RS09505 L-ornithine pyrophosphokinase: phosphotransferase: adenylyltransferase: H839_RS12635 H839_RS00585 H839_RS03890 H839_RS02550 3-ketoacyl- H839_RS03255 succinocarboxamide diphosphate xanthine H839_RS06885 H839_RS05830 H839_RS04615 decarboxylase: H839_RS04545 H839_RS12710 H839_RS17905 H839_RS18220 H839_RS03840 coaD [+ 6 isozymes] [+ 5 isozymes] [+ 4 isozymes] ACP synthase: H839_RS00915 kinase: [1-(2-amino-7-methyl-4-oxo- a [PTS enzyme 3'-dephospho- [+ 3 isozymes] SAICAR (E)-2-methylcrotonoyl-CoA + a (7Z)-3- (R)-1-amino-H839_RS11650 xanthine [+ 2 isozymes] ornithine--oxo-acid π a 5'-phosphooligonucleotide H phosphate ADP a [protein] Ser/Thr reductase: UMP H839_RS11365 2'-deoxyuridine dCMP 7,8-dihydro-3H-pteridin- I]-N -phospho- pyruvate CoA glycine betaine oxotetradec- 2-propanol O glycolate 2,3,4-saturated phosphoribosyltransferase: (S)-3-amino-2- aminotransferase: fabG SAICAR adenylosuccinate enoyl-CoA hydratase: 6-yl)]ethyl diphosphate L-histidine 7-enoyl-[acp] cytidylate kinase: H839_RS09760 hydrogen -2-phosphate [+ 5 isozymes] fatty acyl- dGTP cytidylate kinase: methylpropanoate H839_RS09480 rocD adenylosuccinate lyase: H839_RS11480 thymidine kinase: carbonate a (3R)-3- [acp]:NAD+ H839_RS11480 enoyl-CoA hydratase: L-glutamate-5- lyase: H839_RS00910 H839_RS17215 hydroxyhexanoyl- oxidoreductase: uridylate XMP semialdehyde 6-hydroxymethyl- a (3R,5Z)-3- dCDP H839_RS10635 amino-parathion a uracil 54 in tRNA reduced riboflavin acetyl-CoA [acp] H839_RS03255 H839_RS00910 AICAR kinase: thymidine 7,8-dihydropterin a peptidyl-[tRNA] a charged tRNA a protein GGPP IPP hydroxydodec- dUMP GTP H O 3-hydroxyacyl- pyrH nucleoside 2-methyl-3-hydroxybutyryl-CoA phosphotriesterase: 2-amino-4-hydroxy-6- 2 flavin reductase: heptaprenyl 5-enoyl-[acp]3-oxoacyl-ACP acetyl-CoA AICAR transpeptidase: GTPase RsgA: serine protease: ACP dehydratase: phosphoribosylaminoimidazolecarboxamide diphosphate kinase: L-histidine degradation I H839_RS05685 hydroxymethyldihydropteridine tRNA (uracil-5-)- H839_RS15295 carboxylase: UDP thymidylate thymidine kinase: H839_RS06490 H839_RS00550 diphosphate reductase: 2-methylacetoacetyl- methyltransferase: gid H839_RS04625 H839_RS12245 H839_RS16960 formyltransferase: purH superpathway of adenosine synthase: H839_RS17215 H839_RS11365 phosphotriesterase: pyrophosphokinase: [+ 2 isozymes] [+ 3 isozymes] FMN reductase: synthase: H839_RS03890 phosphoribosylaminoimidazolecarboxamide coenzyme A reductase: L-methionine (S)-1-pyrroline- [+ 5 isozymes] H839_RS18220 a peptidyl- an uncharged 54 H839_RS16685 H839_RS11370 [+ 3 isozymes] a (2E)-hex- formyltransferase: purH nucleotides de novo biosynthesis I H839_RS07490 dCTP 5-carboxylate H839_RS10000 6-hydroxymethyl- a 5-methyluracil a peptide a peptide all-trans- a (5Z)-3-[+ 3 isozymes] FAICAR his H839_RS04690 degradation II aminoacyl-[tRNA] tRNA phosphate GDP H + 4-aminophenol diethylthiophosphate 7,8-dihydropterin in tRNA riboflavin heptaprenyl malonyl-CoA 2-enoyl-[acp] CDP-diacylglycerol biosynthesis III histidine pyrroline-5- oxododec- FAICAR 2-methylacetoacetyl-CoA diphosphate diphosphate hexanoyl-[acyl- ribonucleotide- IMP asp ammonia-lyase: carboxylate 5-enoyl-[acp] phosphoribosylaminoimidazolecarboxamide met carrier-protein] DHAP diphosphate H839_RS01380 reductase: an acyl-[acyl- phosphoribosylaminoimidazolecarboxamide formyltransferase: purH acetyl-CoA methionine reductase: reductase dTMP urocanate H839_RS11990 carrier protein] formyltransferase: purH asp acetyltransferase: gamma-lyase: a plant soluble 4a-hydroxy-N 10 - a protein with an (11Z)-3- glycerol-3- nucleoside subunit alpha: adenylosuccinate 3,4-dihydroxyphenylacetate methyl parathion a 2-oxo butanoate H839_RS03255 thymidylate kinase: H839_RS05405 H839_RS00505 L-ornithine heteroglycan 3'-dephospho- a protein reduced L- oxo-icos-11- diphosphate H839_RS12375 synthetase: urocanate pro carboxylate maltodextrin ATP formyltetrahydrofolate phosphate acyl phosphate H839_RS07915 superpathway of pyrimidine phosphotriesterase: CoA pterin-4-alpha- cysteine residues enoyl-[acp] IMP H839_RS17700 hydratase: [+ 4 isozymes] methionine 3,4-dihydroxyphenylacetate ornithine--oxo-acid serine protease: 3-oxoacyl-ACP a hexanoyl-[acp] dehydrogenase: synthase: IMP kinase: [+ 4 isozymes] nucleobases salvage phosphorylase: dephospho- carbinolamine DSBA butyrate kinase: thymidylate kinase: H839_RS05640 gamma-lyase: 2,3-dioxygenase: H839_RS05685 aminotransferase: H839_RS00550 reductase: gpsA H839_RS04680 H839_RS11365 propanoyl-CoA H839_RS14625 CoA kinase: oxidoreductase: H839_RS12140 adenylo-succinate H839_RS17975 uracil acetyl-CoA H839_RS15355 phosphotriesterase: rocD α dehydratase: H839_RS03890 β-ketooctanoyl- 4-imidazolone- (2Z)-2-aminobut-H839_RS10670 -D- H839_RS13925 [+ 2 isozymes] H839_RS00530 sn-glycerol bifunctional pyrimidine 2-hydroxy-5- H839_RS10000 L-glutamate-5- a proteinogenic a plant soluble H839_RS06600 [+ 3 isozymes] [acp] synthase: an acyl phosphate dTDP 5-propanoate glucopyranose + a peptide a peptide 10 a (3R,11Z)-3- butanoyl inosine-5- adenylosuccinate adenylosuccinate 2-enoate carboxymethylmuconate semialdehyde amino acid heteroglycan ADP coenzyme A H an N -formyl- a protein with 3-phosphate regulatory protein PyrR uracil dimethylthiophosphate 4-nitrophenol 1-phosphate hydroxy-icos- phosphate H839_RS03110 monophosphate synthetase: dUDP lyase: nucleoside imidazolonepropionase: L-serine degradation semialdehyde 7,8-dihydrofolate a disulfide bond inosine-5- phosphoribosyltransferase: 11-enoyl-[acp] a 3-oxooctanoyl- dehydrogenase: H839_RS17700 H839_RS00910 diphosphate kinase: H839_RS05645 acyl-phosphate monophosphate nucleoside H839_RS04505 L-proline [acp] H839_RS04250 H839_RS11365 glycerol 3- dehydrogenase: diphosphate uracil N-formimino- degradation ser inosine-5- gln 2-iminobutanoate D-ribofuranose (25R)-3α,7α-dihydroxy- (S)-1-pyrroline- a [protein]- 3-ketoacyl- phosphate H839_RS04250 adenylo-succinate kinase: AMP dTTP phosphoribosyltransferase: upp L-glutamate serine 2-succinylbenzoate coenzyme A carbamoyl maltohexaose uracil monophosphate UTP met L-ornithine 5-phosphate β 2-deoxygluconate met 5-carboxylate L-tyrosine ACP acyltransferase: H839_RS11365 UMP dehydratase: phosphate 5 -cholestanoyl-CoA inosine-5- dehydrogenase: adenylosuccinate pro O-succinylbenzoate--CoA maltodextrin pseudouridine- 2-deoxy-D- 1-pyrroline-5- phosphate reductase: H839_RS11475 formimidoylglutamase: H839_RS04660 methionine gamma- ornithine alpha-methylacyl- protein-tyrosine monophosphate asp H839_RS17875 lyase: CTP synthetase: dUTP adenylate kinase: cytidylate kinase: proline ligase: H839_RS10150 phosphorylase: 5'-phosphate gluconate 3- N-acetylglutamate carboxylate fabG H839_RS05630 lyase: H839_RS00505 carbamoyltransferase: CoA racemase: phosphatase: dehydrogenase: H839_RS00910 H839_RS17260 H839_RS00260 H839_RS11480 dehydrogenase: serine O-succinylbenzoic acid-- H839_RS14625 glycosidase: dehydrogenase: synthase: dehydrogenase: a 1-acyl-sn dUTPase: methionine gamma- H839_RS03075 α-D- H839_RS05390 [+ 5 isozymes] H839_RS17875 uridylate kinase: pyrH H839_RS15255 2-oxobutanoate dehydratase: H839_RS13840 H839_RS17445 H839_RS03050 H839_RS01000 H839_RS01525 a (3R)-3- -glycerol 3- adenylosuccinate H839_RS08130 superpathway of 5-aminoimidazole glt (S)-1-pyrroline- CoA ligase: H839_RS14585 L-citrulline glucopyranose maltopentaose (25S)-3α,7α-dihydroxy- CTP H839_RS04665 lyase: H839_RS10670 pseudouridine 3-dehydro-2- N-α-acetyl- a [protein]- hydroxyoctanoyl- phosphate synthetase: XMP AMP [+ 3 isozymes] ADP ribonucleotide biosynthesis UDP 5-carboxylate 2-aminoprop- 4-(2'-carboxyphenyl)-4-oxobutyryl-CoA 1-phosphate 5β-cholestanoyl-CoA glt 2-oxobutanoate methanethiol 5'-phosphate deoxy-D-gluconate L-methionine L-tyrosine [acp] acyl-[acp]:1-acyl- H839_RS17700 2-enoate dUMP PRPP nucleoside diphosphate 3-hydroxyacyl- sn-glycerol-3- GMP synthase: adenylate kinase: kinase: H839_RS11365 ACP dehydratase: phosphate 2-O- XMP adenylo-succinate CDP thymidylate amidophosphoribosyltransferase: glycine cleavage H839_RS00260 ATP synthase ribonucleotide- 3-oxo-(6Z,9Z,12Z,15Z,18Z) 10 acyltransferase: H839_RS00875 synthase: H839_RS00935 UTP L-glutamate-5- adenosylcobinamide- α-ribazole salicyl-6-hydroxy-2- a maltodextrin an N - a nucleoside H839_RS16960 subunit J: diphosphate 5-phospho-β- phenylhydantoin a uridine in tRNA a DNA segment gly H839_RS11475 adenylosuccinate ribonucleotide- H839_RS07490 a [glycine- 2-iminopropanoate -tetracosapentaenoyl-CoA GDP 5'-phosphate cyclohexene-on-oyl formyltetrahydrofolate triphosphate a (2E)-oct- H839_RS01605 D-ribosylamine CTP synthetase: semialdehyde beta-ketoadipyl CoA carboxylesterase: maltodextrin tRNA- recombinase a 1,2-diacyl- GMP synthase: lyase: diphosphate reductase cleavage complex cobalamin dihydropteridine nucleoside- 2-enoyl-[acp] GMP ADP dTMP [+ 7 isozymes] subunit alpha: H839_RS17260 1-pyrroline-5- thiolase: H839_RS10500 H839_RS00625 phosphorylase: phenylhydantoinase: dihydrouridine RecX: sn-glycerol H839_RS00875 H839_RS00910 reductase phosphoribosylamine- H protein] N 6 - glycine synthase: reductase: triphosphate glycine oxidase: H839_RS12375 CTP carboxylate H839_RS14625 H839_RS05780 synthase: H839_RS01690 octanoyl-[acyl- 3-phosphate subunit alpha: thymidylate -glycine ligase: lipoyl-L-lysine dehydrogenase: beta-ketoadipyl CoA H839_RS11640 6-hydroxy-2-[+ 2 isozymes] α-D- H839_RS08425 diphosphatase: H839_RS02455 [+ 4 isozymes] dehydrogenase: thiolase: H839_RS10615 10 H839_RS18230 H839_RS13615 [+ 5 isozymes] carrier-protein] phosphatidate guanylate kinase: H839_RS12375 kinase: H839_RS00955 dihydrolipoamide H839_RS12405 adenosylcobalamin salicyl alcohol cyclohexen- glucopyranose a maltodextrin phenylureidoacetic an N -formyl- a DNA segment GMP AMP ribonucleotide- ATP synthase H839_RS01000 (4Z,7Z,10Z,13Z,16Z)- GMP a 5,6-dihydrouridine a nucleoside 5'- reductase: cytidylyltransferase: H839_RS04575 [+ 4 isozymes] H839_RS07915 ATP [+ 2 isozymes] pyruvate acetyl-CoA 5'-phosphate one-carboxylate 1-phosphate 7,8-dihydrofolate in reverse glyoxylate diphosphate subunit J: GAR dehydrogenase: docosapentaenoyl-CoA acid in tRNA H839_RS03255 H839_RS05015 thymidylate monophosphate orientation reductase H839_RS01605 dCDP glt H839_RS12135 a CDP- guanylate kinase: adenylate kinase: kinase: dADP phosphoribosylglycinamide phosphoribosylglycinamide [+ 2 isozymes] GDP subunit alpha: [+ 7 isozymes] a [glycine- an octanoyl-[acp] diacylglycerol H839_RS04575 H839_RS00260 nucleoside H839_RS17975 formyltransferase: formyltransferase: a [glycine-cleavage H839_RS12375 cleavage complex a 5'-half-tRNA luteolin 7-O-β- diphosphate nucleoside H839_RS00945 H839_RS00945 6 β-D-fructofuranose 1-phosphate a 3'-half-tRNA [DNA] NaMN NMN 6 complex H protein] N - acetoacetate 3-phosphonopyruvate molecule with urushiol D-ala β-ketodecanoyl- [+ 4 isozymes] kinase: dTDP H protein] N - L-glutamate D-diglucuronide diphosphate aminomethyldihydrolipoyl- fructose-bisphosphate acetoacetyl- a 2',3'-cyclic molecule with 5'-nucleotidase: 5'-nucleotidase: [acp] synthase: GDP ADP nucleoside ribonucleotide- ATP H839_RS11365 FGAR dihydrolipoyl- degradation I 3-phosphonopyruvate DNA polymerase: kinase: guanine and L-lysine aldolase: H839_RS06975 a 5'-OH end laccase: heme peroxidase: H839_RS07555 H839_RS07555 H839_RS03110 diphosphate diphosphate nucleoside L-phenylalanine degradation I (aerobic) L-lysine CoA synthetase: decarboxylase: phosphate end 2'-5' RNA ligase: H839_RS03635 glycine oxidase: dCTP H839_RS11365 H839_RS04460 H839_RS17395 kinase: diphosphate phosphoribosylformylglycinamidine guanosine salvage fructose-bisphosphate H839_RS10195 H839_RS06450 H839_RS14395 [+ 3 isozymes] 5'-nucleotidase: 5'-nucleotidase: H839_RS02455 a 3-oxodecanoyl- reductase dADP glt kinase: synthase: H839_RS00930 aldolase: H839_RS17245 a ligated tRNA 8'-(3,4-dihydroxy-5-alkenyl) H839_RS15140 H839_RS15140 biotin-carboxyl carrier H839_RS11365 subunit alpha: dATP a tetrahydrobiopterin a radical of luteolin- a nucleoside 5'- β 1-(β-D [acp] ribonucleotide- ribonucleotide- ribonucleotide- ribonucleotide- glutamate AMP diphosphate acetoacetyl-CoA phosphonoacetaldehyde with a 2'-5' linkage phenyl-3-[9'E,11'E,13'Z- -D- pyruvate protein assembly H839_RS12375 nucleoside H839_RS11365 [+ 3 isozymes] guanosine aminomethyltransferase: D-glyceraldehyde DHAP 7-O-diglucuronide monophosphate ribofuranosyl) diphosphate diphosphate diphosphate diphosphate dehydrogenase: pentadecatrienyl]catechol ribosylnicotinate 3-ketoacyl- H839_RS12415 nicotinamide [+ 4 isozymes] diphosphate FGAM purine nucleoside dihydropteridine L-alanine H839_RS11520 ACP biotin carboxyl- reductase reductase ATP synthase reductase reductase dTTP gcv system: nucleoside GTP kinase: pyrimidine ribonucleosides salvage I phosphorylase: reductase: degradation IV 2-oxoglutarate reductase: carrier protein subunit beta: subunit alpha: subunit beta: subunit alpha: diphosphate subunit J: H839_RS11365 phosphoribosylaminoimidazole H839_RS11910 H839_RS08425 H839_RS04090 6 H839_RS02375 H839_RS12375 H839_RS02375 H839_RS12375 R-4'- an O - an (S)-2- a ribonucleoside a [protein]-L- sn-glycerol fabG kinase: H839_RS01605 cytidine a [protein]- S-methyl-L- maltoheptaose a phenolic donor α-amylose bifunctional biotin- dGDP synthetase: H839_RS00940 purine nucleoside L-glutamine phosphopantothenoyl- methylguanine L-homocysteine halocarboxylate proline (ω = 180) [+ 5 isozymes] H839_RS11365 [+ 4 isozymes] [+ 4 isozymes] [+ 4 isozymes] [+ 4 isozymes] ala L-cysteine methionine 5'-monophosphate 3-phosphate -[acetyl-CoA- [+ 7 isozymes] dATP phosphorylase: 4α-hydroxy- L-cysteine in DNA maltodextrin haloacid peptidylprolyl glycerol-3- glycogen a (3R)-3- a 7,8-dihydrobiopterin alanine degradation I methylated-DNA-- homocysteine 5'-nucleotidase: carboxylase] nucleoside uridine kinase: cytidine AIR H839_RS09615 phosphorylase: dehalogenase: heme peroxidase: isomerase: branching hydroxydecanoyl- tetrahydrobiopterin dehydrogenase: L-aspartate phosphopantothenoylcysteine protein-cysteine S- methyltransferase: H839_RS07555 phosphate H839_RS05825 deaminase: guanine H839_RS14625 H839_RS17395 H839_RS11835 protein: [acp] synthetase/ diphosphate decarboxylase: H839_RS04585 H839_RS02870 α-D- H839_RS02550 acyltransferase: H839_RS12710 CMP H839_RS14050 gln degradation I methyltransferase: [+ 2 isozymes] H839_RS14645 3-hydroxyacyl- biotin operon dGDP dADP kinase: uridine kinase: [+ 4 isozymes] [+ 2 isozymes] H839_RS07540 phosphorylation alanine GMP synthase: H839_RS15515 met glucopyranose maltohexaose a phenoxyl radical a [protein]-L- a 1-acyl-sn repressor: H839_RS11365 H839_RS13005 xanthine 4'-phosphopantetheine a [protein]-S- a halide anion an (R)-2- a ribonucleoside amylopectin ACP dehydratase: H839_RS00875 asp a guanine in DNA 1-phosphate of a phenolic donor -glycerol 3- H839_RS11215 uridine phosphoribosyltransferase: dehydrogenase: methyl-L-cysteine hydroxyacid proline (ω = 0) H839_RS16960 CMP [+ 6 isozymes] phosphate GTP ATP dGTP CMP H839_RS09760 pterin-4-alpha- H839_RS17515 aspartate nucleoside nucleoside uridine kinase: cytidylate kinase: pyruvate a (2E)-dec- a biotinylated carbinolamine glt aminotransferase: diphosphate diphosphate H839_RS05825 H839_RS11480 hypoxanthine 2-enoyl-[acp] [BCCP monomer] dehydratase: H839_RS11180 a (1->4)- CDP phosphoribosyltransferase: phosphatidylglycerophosphate phosphoenol + (R)-3- kinase: kinase: uridine kinase: oxaloacetate an α-D-galactoside a glycogen FMNH NAD(P) DNA with lesion α decanoyl-[acyl- H839_RS06600 2 Ins(1)P an L-amino acid -D-glucan H839_RS11365 H839_RS11365 H839_RS13005 nucleoside H839_RS18170 (1-octadecenoyl(9Z), 2-palmitoyl) pyruvate hydroxybutanoate carrier-protein] L-glutamate alpha-galactosidase: maltodextrin flavin reductase: excinuclease glycogen diphosphate phosphoenolpyruvate 3-hydroxybutyrate inositol reductase: UMP degradation X phosphatidylglycerophosphatase: H839_RS06080 phosphorylase: H839_RS15295 ABC subunit C: amino acid branching kinase: GMP phosphomutase: dehydrogenase: monophosphatase: H839_RS03255 a biotinylated L-asparagine H839_RS15060 alpha-galactosidase: H839_RS14625 FMN reductase: H839_RS13670 racemase: protein: H839_RS11365 Secondary Metabolite Degradation H839_RS06445 α-D- H839_RS06605 H839_RS04135 dGTP dATP degradation I glt H839_RS11065 H839_RS16685 [+ 2 isozymes] H839_RS05695 H839_RS14645 [BCCP dimer] 1-oleoyl-2-palmitoyl- glucopyranose maltotetraose a non galactosylated 3-phosphonopyruvate + acetoacetate DNA without a decanoyl-[acp] CTP glutamate α-D-galactose 1-phosphate H NAD(P)H FMN myo-inositol a D-amino acid starch biotin anhydromuropeptides recycling phosphatidylglycerol lesion biotin mannitol asn dehydrogenase: galactose acceptor β-ketododecanoyl- carboxylase: carboxylase: degradation I asparaginase: H839_RS11520 [acp] synthase: H839_RS09495 GlcNAc-1,6- 2-oxoglutarate H839_RS09495 anhMurNAc- H839_RS11510 H839_RS03110 [+ 5 isozymes] D-mannitol (S)-methylmalonyl- a (1->4)- L-Ala-γ-D-Glu- 1-(3-sn-phosphatidyl)- D-cellobiose maltopentaose HMP-P a tetrahydrobiopterin D-glucopyranose an oxidized a 3- a carboxylated- Metabolic Regulator 1-phosphate asp CoA α-D-glucan mannitol-1- sn-glycerol 3-phosphate a tRNA precursor CTP ATP cellobiose maltodextrin cytochrome c biotinylated Biosynthesis DAP-D-Ala phosphomethylpyrimidine xylose isomerase: methylmalonyl- 3 glycogen oxododecanoyl- phosphate 5- dihydropteridine [acp] [BCCP dimer] phosphatidylglycerophosphatase: tRNA CCA- phosphorylase: phosphorylase: kinase: H839_RS09980 H839_RS06135 CoA cytochrome-c3 branching ppGpp biosynthesis dehydrogenase: reductase: 3-ketoacyl- N-acetylmuramoyl- H839_RS15060 pyrophosphorylase: H839_RS06570 H839_RS14625 xylose isomerase: decarboxylase: hydrogenase: protein: H839_RS06730 α-D- α-D- pyridoxal kinase: H839_RS08425 ACP Cell Structure Biosynthesis Secondary Metabolite Biosynthesis L-alanine a tRNA H839_RS11220 H839_RS17520 H839_RS14665 H839_RS10895 H839_RS07635 H839_RS14645 F6P an L-1-phosphatidyl- D-glucopyranose glucopyranose glucopyranose maltotetraose 6,7- reductase: pppGpp amidase: containing a a reduced a glycogen sn-glycerol 1-phosphate 1-phosphate HMP-PP dihydrobiopterin keto-D-fructose propanoyl-CoA fabG GTP pyrophosphokinase: peptidoglycan biosynthesis I (meso-diaminopimelate containing) methylerythritol phosphate pathway II H839_RS00330 3' CCA end cytochrome c phosphatidylethanolamine preQ biosynthesis 3 [+ 5 isozymes] H839_RS03230 0 myo-inositol [+ 2 isozymes] biosynthesis I UDP-N-acetyl- biosynthesis C1 Compound Utilization and Assimilation a (3R)-3- (p)ppGpp synthetase: guanosine 3'-diphosphate α-D-glucosamine pyruvate D-glyceraldehyde 3-phosphate N-acetyl-β-D- L-alanyl-γ-D- α γ a long-linear all-trans- hydroxydodecanoyl- H839_RS13135 5'-triphosphate 3'- D-glucopyranose an -( -L-glutamyl) + (R)-methylmalonyl- O-acetyl-L- α FMNH NADP porphobilinogen baicalein DHAP [acp] a CDP-diacylglycerol diphosphatase: UDP-N-acetylglucosamine GTP glucosamine(anhydrous) glutamyl-meso-2,6- formate assimilation into 5,10- methanethiol -L-amino acid -D-glucan 2 heptaprenyl 1-deoxy-D-xylulose- 6-phosphate homoserine cobinamide ATP maltodextrin CoA phosphatidylserine GTP -N-acetylmuramate diaminopimeloyl- methylenetetrahydrofolate reductive monocarboxylic acid cycle gamma-glutamyl FMN reductase: methylmalonyl- diphosphate (3R)-3- H839_RS13135 1-carboxyvinyltransferase: 5-phosphate O-acetylhomoserine porphobilinogen tetraprenyl- methylglyoxal synthase: beta-N- D-alanine ATP:cob(I)alamin cyclotransferase: phosphorylase: H839_RS16685 heme peroxidase: CoA hydroxydodecanoyl H839_RS17010 cyclohydrolase: aminocarboxypropyltransferase: deaminase: beta-curcumene synthase: H839_RS12910 synthase: 7,8- acetylhexosaminidase: adenosyltransferase: H839_RS14625 H839_RS17395 dehydratase: a 3-sn-phosphatidyl- H839_RS11390 formate acetyl-CoA H839_RS15205 H839_RS09300 α flavin reductase: H839_RS13510 decarboxylase: H839_RS11235 UDP-N-acetylglucosamine H839_RS12205 dihydroneopterin Ins(3)P -D- synthase: ppGpp H839_RS10415 H839_RS11625 a long-linear H839_RS15295 H839_RS10895 H839_RS16960 L-serine GTP 1-carboxyvinyltransferase: formate:tetrahydropteroylpolyglutamate acetate met 5-oxo-L-proline an L-amino acid glucopyranose 6,7- H839_RS14475 3'-triphosphate PPP adenosylcobinamide α + preuroporphyrinogen methylglyoxal 1,6-anhydro-N- i -D-glucan tetraprenyl- a (2E)-dodec- phosphatidylserine H839_RS17235 1-deoxy-D-xylulose 5-phosphate inositol L-alanyl-γ-D- ligase: H839_RS12225 1-phosphate H NADPH FMN dehydrobaicalein propanoyl-CoA 6-carboxy-5,6,7,8- acetyl-β-muramate an N 10 - formate pyruvate:ferredoxin β-curcumene 2-enoyl-[acp] decarboxylase: UDP-N-acetyl-α- monophosphatase: glutamyl-meso- 1-deoxy-D-xylulose tetrahydropterin formyltetrahydrofolate acetyltransferase: oxidoreductase: H839_RS12905 D-glucosamine- H839_RS04135 diaminopimelate dodecanoyl-[acyl- GTP pyrophosphokinase: 5-phosphate synthase: 5,10-methylene- H839_RS17575 H839_RS05250 an L-1- enolpyruvate UDP-N- (2Z,4E)-2- H839_RS03750 α + a [heparan-sulfate]-2- carrier-protein] H839_RS03230 guanosine-3',5'- reductoisomerase: myo-inositol acetylmuramate:L- tetrahydrofolate a glycogen -D- FMNH NAD betanidin a nucleotide phosphatidylethanolamine UDP-N- N-acetyl-β- an N-formyl-L-methionylaminoacyl-tRNA DL-allothreonine 2 α hydroxyhexa- ethylphosphate reductase: bis(diphosphate) H839_RS05020 6-carboxy-5,6,7,8- γ cyclohydrolase: glucopyranose ATP O-sulfo- -L-iduronate acetylenolpyruvoylglucosamine muramate 6- alanyl- -D- maltodextrin FMN reductase: 2,4-dienedioate H839_RS03255 nucleoside diphosphate 3'-diphosphatase: tetrahydropterin pyruvate peptide deformylase: serine 1-phosphate iduronate alkaline glutamyl-meso- H839_RS12225 phosphorylase: H839_RS16685 heme peroxidase: 4-oxalocrotonate nucleotidase: kinase: H839_RS11365 reductase: H839_RS04405 phosphate H839_RS04595 hydroxymethyltransferase: glucose-1-phosphate sulfatase: phosphatase: H839_RS13135 MEP 7-carboxy-7- diaminopimelate a 5,10- H839_RS14625 H839_RS17395 tautomerase: H839_RS12610 a dodecanoyl-[acp] UDP-N- N-acetylmuramic peptide deformylase: def H839_RS17135 α-D- adenylyltransferase: flavin reductase: H839_RS15840 H839_RS17650 GDP deazaguanine ligase: methenyltetrahydrofolate H839_RS17355 acid-6- α glgC H839_RS15295 acetylenolpyruvoylglucosamine 2-C-methyl-D- synthase: formate a L-methionylaminoacyl-tRNA gly acetaldehyde glucopyranose an -limit dextrin a [heparan sulfate]- (3E)-2-oxohex- [+ 6 isozymes] H839_RS14325 5,10-methylene- ADP-α-D-glucose + betanidin quinone a nucleoside reductase: murB phosphate 1-phosphate H NADH FMN α-L-iduronate long-chain fatty erythritol 4-phosphate H839_RS03755 UDP-N-acetyl- 3-enedioate ethanol β-ketomeristoyl- glt ala etherase: murQ tetrahydrofolate acid activation UDP-N-acetyl- cytidylyltransferase: N-acetyl-D- α-D-muramoyl- [acp] synthase: gluconeogenesis I Carbohydrate Biosynthesis 7-carboxy-7- cyclohydrolase: α-D-muramate H839_RS00035 γ H839_RS03110 a long-chain GDP-mannose biosynthesis UDP-galactofuranose glutamate deazaguanine glucosamine L-alanyl- -D- H839_RS12225 α 4-(cytidine 5'-diphospho) a linear malto- laurate biosynthesis UDP- -D-glucuronate racemase: 6-phosphate glutamyl-meso-2,6- 2503 an acyl- a 5,6,7,8- sn-glycerol fatty acid UDP-N- 7-cyano-7- a 5,10- adenine in 23S rRNA oligosaccharide butanoyl-CoA phosphate a double stranded DNA asp pyruvate long-chain fatty (S)-malate D-glucopyranose biosynthesis (from H839_RS13630 -2-C-methyl-D-erythritol N-acetylglucosamine- diaminopimelate coenzyme A 2-oxoglutarate D-ala tetrahydropteridine 3-phosphate acetylmuramate- deazaguanine methylenetetrahydrofolate 23S rRNA (adenine(2503) carrier protein maltodextrin a 3-oxotetradecanoyl- long-chain fatty acid--CoA ligase: 6-phosphate UDP-α-D-glucose UDP-glucose) 4-diphosphocytidyl- 6-phosphate 4'-phosphopantetheinyl phosphate D-alanine DNA gyrase dihydropteridine glycerol-3- pyruvate glucose-6- amino acid -alanine ligase: synthase: -C(2))-methyltransferase phosphorylase: aspartate [acp] acid--CoA ligase: H839_RS05380 malate dehydrogenase: UDP-glucose α 2C-methyl-D- deacetylase: ketogluconate metabolism transferase: butyryltransferase: aminotransferase: subunit B: gyrB reductase: phosphate carboxylase: phosphate UDP- -D-glucose racemase: H839_RS14325 H839_RS03745 Detoxification RlmN: H839_RS04610 H839_RS14625 aminotransferase: 3-ketoacyl- H839_RS02680 [+ 5 isozymes] H839_RS10375 4-epimerase: erythritol kinase: H839_RS11725 H839_RS00640 α-D- H839_RS12150 H839_RS02700 [+ 3 isozymes] H839_RS08425 acyltransferase: H839_RS04190 a long-chain malate dehydrogenase: isomerase: UDP-glucose 6- H839_RS05695 a linear malto- butanoyl H839_RS11180 [+ 5 isozymes] H839_RS11050 H839_RS07770 preQ 2,5-didehydro- a 2-methyladenine 2503 in 23S rRNA 5'-deoxyadenosine met a negatively a 6,7- H839_RS07540 ACP fatty acyl-CoA H839_RS13955 dehydrogenase: UDP-N-acetyl- 0 D-glucosamine acyl-carrier protein 3',5'-ADP glucopyranose pyruvate D-glt H839_RS14865 reactive oxygen species degradation oxidized GTP and oligosaccharide phosphate oxaloacetate 1-oleyl-2-lyso- oxaloacetate reductase: F6P α [+ 4 isozymes] H839_RS11605 D-glt α-D-muramoyl- 4-diphosphocytidyl- 6-phosphate D-gluconate 1-phosphate supercoiled DNA dihydropteridine lauroyl-CoA malate dehydrogenase: UDP- -D- dGTP detoxification phosphatidate fabG L-alanine 2C-methyl-D- H839_RS10375 galactose UDP-glucose 6- phosphoglucosamine [+ 5 isozymes] mannose-6- erythritol kinase: ipk superoxide oxaloacetate UDP-N-acetyl-D- UDP- dehydrogenase: mutase: H839_RS00450 a (3R)-3- phosphate UDP-N- 2-phospho-4-(cytidine 5'- 2-(2-carboxy-4- 2-deoxy-5-dehydro- a dipeptide with a glucosamine biosynthesis I galactopyranose α H839_RS16555 superoxide dismutase: dGTP GTP a 2-oxo carboxylate a proteinogenic a double a benzenediol hydroxypyruvate sn-glycerol precorrin-6B hydroxytetradecanoyl- isomerase: UDP- -D- acetylmuramoyl- D-glucosamine glutathione methylthiazol-5- HMP-PP D-gluconate pyruvate mutase: diphospho)-2-C-methyl-D-erythritol autoinducer AI-2 biosynthesis I 2-keto-L-gulonate H839_RS11775 amino acid stranded DNA C-terminal L-proline 3-phosphate [acp] phosphoenolpyruvate D-glucopyranose H839_RS17630 glucuronate L-alanyl-D- 1-phosphate 2-oxoacid ferredoxin yl)ethyl phosphate Xaa-Pro H839_RS16905 2-C-methyl-D- [+ 2 isozymes] gamma- thiamine-phosphate 5-dehydro-2- hydroxypyruvate glycerol-3- precorrin-6x 3-hydroxyacyl- carboxykinase: 6-phosphate D-mannopyranose glutamate oxidoreductase: endonuclease I: dipeptidase: laccase: stearate biosynthesis glucose-6- erythritol 2,4- bifunctional N- 2,5-diketo-D- glutamyltransferase: pyrophosphorylase: deoxygluconokinase: isomerase: phosphate reductase: ACP dehydratase: H839_RS14505 6-phosphate UDP-Galf synthetase: murD 8-oxo-dGTP 8-oxo-GTP H839_RS05250 H839_RS07040 H839_RS12305 H839_RS04460 II (bacteria and plants) phosphate cyclodiphosphate SAM acetylglucosamine- gluconic acid hydrogen peroxide H839_RS16995an α-(γ-L- thiE H839_RS06965 H839_RS09870 dehydrogenase: H839_RS07290 H839_RS16960 + a reduced ferredoxin 5-dehydro-2-deoxy-D- a proteinogenic isomerase: phosphomannomutase: synthase: 1-phosphate reductase: 7,8-dihydro-8- H CO an acyl-CoA L-cysteinyl-glycine glutamyl)-L- thiamin phosphate pro tartronate gpsA UDP-N-acetyl- [iron-sulfur] cluster 2 a 5'-phosphooligonucleotide amino acid a benzosemiquinone precorrin-6A a (2E)-tetradec- a palmitoyl-[acp] H839_RS14865 H839_RS01230 meso- H839_RS00040 uridyltransferase/ L-idonate oxoguanine- amino acid gluconate 6-phosphate semialdehyde DHAP phosphoenolpyruvate α-D-muramoyl-L- H839_RS08635 catalase: 2-enoyl-[acp] F6P α diaminopimelate glucosamine- triphosphatase: -D-mannose alanyl-D-glutamate SAH H839_RS00965 2-C-methyl-D-erythritol- 1-phosphate H839_RS14535 8-oxo-GMP myristoyl-[acyl- enolase: eno glucosamine- 1-phosphate PRPP biosynthesis I 2,4-cyclodiphosphate acetyltransferase: [dermatan-sulfate] a 3-oxooctadecanoyl- H O hydroxyl radical 10 (2R,3S)-3- indole-3- carrier-protein] -fructose-6- UDP-N- 5'-methylthioadenosine 2 an N - an L-methionyl- a 5-L-glutamyl- 4-hydroxy-3- glmU O 8-oxo-dGMP L-canaline carbamoyl propanoyl-CoA phosphate containing 2-O- 3-ethylmalate maleate reductase: [acp] D-ribose 5- acetylmuramoylalanyl- nucleosidase: 5-dehydro- 2 Met an amino acid a type IV prepilin isopropylmalate acetonitrile phosphate α formyltetrahydrofolate [initiator tRNA ] [peptide] phosphate α 2-phospho-D-glycerate phosphate methylbut-2-en-1- N-acetyl- -D- D-gluconate methionyl-tRNA gamma- phosphate prepilin sulfo- -L-iduronate 3-isopropylmalate 3-isopropylmalate nitrilase: maleate cis- H839_RS03255 3-ketoacyl- aminotransferase: GDP-α-D- ribose-phosphate D-glutamate--2, 6- H839_RS12970 ornithine iduronate yl diphosphate glucosamine formyltransferase: acyltransferase: H839_RS10470 ACP 2,3-bisphosphoglycerate- H839_RS00455 pyrophosphokinase: diaminopimelate glutamyltransferase: carbamoyltransferase: peptidase: dehydrogenase: dehydrogenase: trans isomerase: mannose D-ala synthase: 1-phosphate 2-keto-D- sulfatase: nitrilase: a myristoyl-[acp] reductase: ligase: H839_RS04380 S-ribosyl-L-homocysteine gluconate 5- an N-formyl- H839_RS04600 an αH839_RS16995-(5-L- H839_RS03075 H839_RS04680 H839_RS13410 H839_RS13570 H839_RS13570 H839_RS01060 independent D-glucosamine H839_RS18075 propanoyl a cleaved type H839_RS15840 H839_RS12600 bifunctional N- dehydrogenase: gluconate L-methionyl- a tetrahydrofolate O-ureidohomoserine a [dermatan] containing 4-methyl-2- H839_RS16690 fabG phosphoglycerate 6-phosphate PRPP a peptide glutamyl)- phosphate a peptide 2-oxovalerate fumarate β-ketopalmityl- D-alanine- H839_RS03905 met IV prepilin indole-3-acetate [+ 5 isozymes] mutase: H839_RS15470 UDP-N-acetyl- 1-hydroxy-2-methyl-2-(E) S-ribosylhomocysteinase: acetylglucosamine- [initiator tRNA ] amino acid α-L-iduronate oxopentanoate [acp] synthase: a (3R)-3- phosphoglucosamine -D-alanine α-D-muramoyl- -butenyl 4-diphosphate H839_RS14555 1-phosphate H839_RS03110 hydroxyoctadecanoyl- 3-phospho-D-glycerate mutase: H839_RS00450 UDP-glucose biosynthesis ligase: ddl L-alanyl-γ-D- uridyltransferase/ a 3-oxohexadecanoyl- [acp] D-glucosamine glutamyl-meso-2,6- AI-2 glucosamine- D-gluconate a 2'- D-gluconate an organic D-alanyl-D-alanine 4-hydroxy-3- (deoxynucleotides) [DNA] NAD + 5-aminolevulinate uroporphyrinogen-I L-cysteate precorrin-2 butanal phosphoglycerate (m) O-ureidohomoserine deoxyribonucleoside [DNA] [acp] 3-hydroxyacyl- 1-phosphate D-glucopyranose diaminopimelate methylbut-2-enyl 1-phosphate asp 6-phosphate hydroperoxide kinase: pgk acetyltransferase: gluconokinase: 5'-triphosphate peroxiredoxin: ACP dehydratase: bifunctional N- 6-phosphate diphosphate NAD-dependent acyl--CoA ligase: argininosuccinate DNA polymerase: uroporphyrinogen 6-phosphogluconate aspartate precorrin-2 C20- butanol 3-ketoacyl- phosphoglucomutase: 4-hydroxy-3- H839_RS06775 H839_RS01845 H839_RS16960 UDP-N- glmU DNA ligase LigA: ligA H839_RS14220 synthase: H839_RS03635 decarboxylase: dehydrogenase: methyltransferase: ACP 13-DPG acetylglucosamine- H839_RS16860 methylbut-2-enyl reductase: aminotransferase: dehydrogenase: acetylmuramoyl- (2R,4S)-2-methyl-2,4- UDP-N-acetyl- D-gluconate H839_RS02650 H839_RS12015 H839_RS07310 peroxiredoxin: reductase: a (2E)-octadec- 1-phosphate phosphoglucomutase: diphosphate H839_RS12650 5-aminolevulinyl- H839_RS14070 [+ 10 isozymes] H839_RS11180 H839_RS14870 tripeptide-- dihydroxydihydrofuran-3-one α-D-glucosamine 6-phosphate AMP NMN (deoxynucleotides) diphosphate AMP D-ribulose H839_RS07545 fabG 2-enoyl-[acp] glyceraldehyde-3- uridyltransferase/ H839_RS02125 reductase: isopentenyl (m) CoA canavaninosuccinate [DNA] α-D-glucopyranose D-alanyl-D- coproporphyrinogen I 3-sulfopyruvate precorrin-3A n-butanol phosphate dehydrogenase: glucosamine- H839_RS12650pyrophosphate 5-phosphate an alcohol [+ 5 isozymes] 2,3,4-saturated 1-phosphate alanine ligase: IPP a (3R)-3- fatty acyl- triosephosphate H839_RS13920 1-phosphate isomerase: acetyltransferase: UTP--glucose- H839_RS00620 H839_RS11465 hydroxyhexadecanoyl- [acp]:NAD+ isomerase: tpiA (2R,4S)-2-methyl-2,3,3,4- DHAP D-glyceraldehyde 3-phosphate 1-phosphate [+ 2 isozymes] 4-methyl-5-(2- a (1->4)- [acp] oxidoreductase: glmU an adenosine 37 (2E,6E)-farnesyl a single- succinate tetrahydroxytetrahydrofuran DMAPP phosphonooxyethyl) HMP-PP heme b α a RNA-DNA hybrid trans-dienelactone a dextran 3-hydroxyacyl- N-acetyl-α-D- uridylyltransferase: diphosphate stranded RNA -D-glucan L-saccharopine semialdehyde H839_RS03255 UDP-N-acetyl- in tRNA polynucleotide maltodextrin ACP dehydratase: glucosamine H839_RS16830 DMAPP Inorganic Nutrient Metabolism tRNA delta(2)- thiazole thiamine-phosphate protoheme IX ribonuclease H: saccharopine dienelactone succinate- glucan 1,6-alpha- α-D-muramoyl- phosphorylase: phosphorylase: H839_RS16960 a stearoyl-[acp] fructose-bisphosphate 1-phosphate UTP--glucose- isopentenylpyrophosphate pyrophosphorylase: farnesyltransferase: H839_RS04765 dehydrogenase: hydrolase: semialdehyde glucosidase: L-alanyl-γ-D- H839_RS05090 H839_RS14625 aldolase: H839_RS06975 superpathway of sulfate assimilation transferase: H839_RS05365 thiE H839_RS04200 α [+ 2 isozymes] H839_RS01335 H839_RS16500 dehydrogenase: H839_RS06575 bifunctional N- 1-phosphate 6 37 -D- a (2E)-hexadec- glutamyl-meso-2,6- di-trans,octa-cis selenate reduction N -dimethylallyladenosine a nucleoside a single- a (1->4)- a nucleoside 5'- gabD uridylyltransferase: and cysteine biosynthesis thiamin phosphate heme o DNA allysine glucose 2-enoyl-[acp] fructose-bisphosphate acetylglucosamine- diaminopimeloyl- in tRNA diphosphate stranded RNA glucopyranose α-D-glucan monophosphate glt 2-maleylacetate H839_RS16915 -undecaprenyl succinate aldolase: H839_RS17245 1-phosphate fructan biosynthesis D-alanyl-D-alanine 3-phospho- 1-phosphate palmitoyl-[acyl- phosphate selenate uridyltransferase/ α D-glycerate carrier-protein] UDP- -D-glucose sulfate stearate glucosamine- sucrose phospho-N- D-3- reductase: adenylyltransferase: sat fructose 1,6-bisphosphate 1-phosphate a proteinogenic (S)-4-amino-5- a damaged succinate H839_RS03255 long-chain fatty acetylmuramoyl- sulfate phosphoglycerate adenosine 5'- a peptidoglycan a peptide with a glu H O diphosphate precorrin-8x pullulan leukotriene-C4 asp fumarate a tRNA 2 DNA pyrimidine semialdehyde acetyltransferase: pentapeptide dehydrogenase: amino acid leader sequence oxopentanoate acid--CoA ligase: levansucrase: phosphoselenate N-acetylmuramoyl-L-alanine glutamyl-tRNA inorganic succinate- a palmitoyl-[acp] fructose 1,6- glmU transferase: sulfate H839_RS11595 gamma- signal peptidase L-aspartate precorrin-8X pullulanase: H839_RS02680 H839_RS17500 amidase: H839_RS00330 diphosphatase: DNA glycosylase: semialdehyde bisphosphatase: glpX UDP-N-acetyl- adenylyltransferase: sat glutamyltransferase: I: H839_RS04755 oxidase: reductase: methylmutase: H839_RS04390 3-phospho- [+ 2 isozymes] H839_RS01720 dehydrogenase: H839_RS14385 [+ 5 isozymes] α-D-glucosamine 1-kestotriose H839_RS16995 H839_RS13240 H839_RS13520 H839_RS11590 H839_RS07295 hydroxypyruvate ditrans,octacis-undecaprenyldiphospho- an α-(γ-L-glutamyl) a leader sequence a peptide an L-glutamyl- F6P 6-kestotriose APS a peptidoglycan pentapeptide phosphate H + an apyrimidinic gabD stearoyl-CoA undecaprenyldiphospho- leukotriene-D4 succinate 2-iminosuccinate Glu maltotriose 3-phosphoserine selenite N-acetyl-(N-acetylglucosaminyl)muramate -L-amino acid [tRNA ] hydrogenobyrinate succinate N-acetylmuramoyl-L- site in DNA glucose-6-phosphate levansucrase: adenylylsulfate aminotransferase: alanyl-γ-D-glutamyl-meso palmitate isomerase: H839_RS14865 H839_RS17500 kinase: H839_RS02595 -2,6-diaminopimeloyl- H839_RS01500 γ long-chain fatty 1,1-kestotetraose 6 -kestotriose a [glycine-cleavage an oxidized a peptide with -L-glutamyl-(S)- 34 a (2S)-2- a glucosylated uridine D-glucopyranose 6-phosphate G D-alanyl-D-alanine 3-phospho- a cytidine an L-asparaginyl- 1,6-kestotetraose SAM complex H protein] a sulfurated [sulfur carrier] ammonium H O ferredoxin [iron- a tRNA precursor an N-terminal trans-1-propenyl- lys glycogenin acid--CoA ligase: UDP-diphospho- PAPS L-serine selenodiglutathione 2 in tRNA Ile2 methylacyl-CoA [tRNA Asn ] uridine kinase: 6 glycogen H839_RS02680 N -octanoyl-L-lysine ferredoxin--sulfur] cluster ribonuclease Z: D-amino acid L-cysteine tRNA(Ile)-lysidine alpha-methylacyl- peptidyl-tRNA muramoylpentapeptide beta-N- phosphoserine lipoyl synthase: D-aminopeptidase: aminopeptidase branching H839_RS05825 [+ 5 isozymes] acetylglucosaminyltransferase: phosphoadenosine nitrite reductase: H839_RS12000 synthetase: CoA racemase: hydrolase: Aromatic Compound phosphatase: H839_RS15095 a [glycine-cleavage H839_RS01085 S-transA: H839_RS14950-1- protein: uridine kinase: phosphosulfate H839_RS01495 H839_RS18165 H839_RS05390 H839_RS18085 H839_RS00595 Degradation H839_RS17650 an unsulfurated a single-stranded 34 palmitoyl-CoA 5'-deoxyadenosine met complex H protein] mature tRNA a D-amino acid a peptide glt propenyl- a lysidine H839_RS14645 H839_RS13005 lipid II (meso reductase: [sulfur carrier] nitrite oligoribonucleotide a (2R)-2- tRNA Asn asn N 6 -lipoyl-L-lysine L-cysteine in tRNA Ile2 a glycogen UMP diaminopimelate phenylacetate H839_RS01510 ser glutathioselenol methylacyl-CoA containing) degradation I (aerobic) sulfite serine a [protein]- coenzyme A phenylacetate acetyltransferase: urea cycle 5,10-methylene- 3-methyl-2- an α-D-mannoside 5-chloro-5- cytidine glutathione hypoglycin A an alkylamine a methyl jasmonate a protein wound RNA cis-dienelactone phenylacetate- tetrahydromethanopterin oxobutanoate L-glutamine deoxy-D-ribonate uridine kinase: H839_RS00050 3-methyl-2-oxobutanoate alpha- transglutaminase: carboxylesterase: -CoA ligase: hydrogen selenide gamma- bacillolysin: dihydroxy-acid DNA/RNA dienelactone H839_RS05825 hydroxymethyltransferase: mannosidase: H839_RS00870 H839_RS00625 H839_RS10665 O-acetyl-L-serine arg glutamyltransferase: dehydratase: helicase: hydrolase: hydrogen sulfide H839_RS16760 H839_RS16800 uridine kinase: phenylacetyl-CoA H839_RS11210 [+ 2 isozymes] [+ 2 isozymes] H839_RS10675 H839_RS10820 H839_RS16500 H839_RS16995 a non glycosylated a protein-N 5 - H839_RS13005 THMPT 2-dehydropantoate α-D-mannose methanol a jasmonate a peptide a peptide arginase: L-cysteinyl-glycine hypoglycin B sugar acceptor alkylglutamine 5-chloro-4-hydroxy- an unwound RNA ring 1,2- argininosuccinate ammonium 2-maleylacetate CMP cysteine H839_RS00425 2-oxopentanoate phenylacetyl-CoA synthase: lyase: arginase: carbamoyl epoxidase: paaA H839_RS18190 H839_RS14065 H839_RS01470 phosphate a 2,3,4-saturated 2-(1,2-epoxy-1,2- parathion degradation an all-trans methyl (indol- 1-chloro-2,4- dTTP synthase AICAR CTP 1,2-diacyl-sn- glutathione isovaleryl-CoA citrate a phenol sulfate dihydrophenyl)acetyl-CoA -retinyl ester 3-yl)acetate dinitrobenzene a protein nucleoside- cys L-arginino- large subunit: adenine glycerol 3-phosphate carboxylesterase: carboxylesterase: glutathione isovaleryl-CoA aconitate 1,2- parathion L-ornithine phosphatidate peptidase: sulfatase: triphosphate succinate H839_RS03070 phosphoribosyltransferase: H839_RS00625 H839_RS00625 transferase: dehydrogenase: hydratase: epoxyphenylacetyl- thiosulfate cytidylyltransferase: H839_RS12820 H839_RS13695 diphosphatase: [+ 3 isozymes] H839_RS13140 [+ 2 isozymes] [+ 2 isozymes] H839_RS10890 H839_RS05535 CoA isomerase: disproportionation 5-amino-4- H839_RS05015 a long-chain 2,4-dinitrophenyl- H839_RS10145 H839_RS13615 phosphotriesterase: a CDP-2,3,4-saturated- methanol a peptide a peptide III (rhodanese) carbamoyl PRPP all-trans-retinol indole-3-acetate 3-methylcrotonyl- H839_RS10630 H839_RS05685 imidazolecarboxyamide diacylglycerol fatty acid S-glutathione D-threo-isocitrate a phenol dTMP phosphate CoA 2-oxepin-2(3H)- phosphotriesterase: thiosulfate ornithine argininosuccinate ylideneacetyl-CoA H839_RS10000 rhodanese: carbamoyltransferase: synthase: β H839_RS02250 H839_RS03075 an N-acetyl- - 7,8- all-trans- 1-O- UTP H839_RS14070 3-mercaptopyruvate hydrogen cyanide D-hexosaminide a uracil in DNA isovaleryl-CoA a tRNA sec ser urushiol rhodanese dihydroneopterin retinyl palmitate methylsalicylate nucleoside- diethylthiophosphate 4-nitrophenol L-citrulline 3-mercaptopyruvate beta-N- dihydroneopterin carboxylesterase: uracil-DNA carboxylesterase: domain protein: isovaleryl-CoA seryl-tRNA triphosphate 3-oxo-5,6-didehydrosuberyl- sulfurtransferase: acetylhexosaminidase: aldolase: H839_RS15435 glycosylase: H839_RS00625 laccase: H839_RS02255 dehydrogenase: synthetase: diphosphatase: CoA semialdehyde H839_RS09710 H839_RS10415 H839_RS18215 [+ 2 isozymes] H839_RS17425 [+ 2 isozymes] H839_RS04460 sulfite thiocyanate β H839_RS10145 H839_RS17895 an N-acetyl- - 6-hydroxymethyl- an apyrimidinic an L-seryl- H839_RS13615 pyruvate thiocyanate an alcohol glycolaldehyde palmitate all-trans-retinol uracil methanol salicylate 3-methylcrotonyl- dimeric urushiol D-hexosamine 7,8-dihydropterin site in DNA [tRNA sec ] UMP CoA peroxide 3-oxo-5,6- diethylphosphate didehydrosuberyl-CoA 7,8- all-trans- CTP + a carboxylic ester + an L-cysteinyl- β-D-fructofuranose 3-oxo-5,6- H 4-coumaryl-CoA malonyl-CoA NADPH nicotinate PRPP A NADPH H retinyl palmitate pyruvate dihydromonapterin [tRNA Cys ] nucleoside- dehydrosuberyl- chalcone synthase: nicotinate dihydroneopterin carboxylesterase: NADPH carboxylesterase: peptidyl-tRNA fructokinase: pyruvate kinase: triphosphate CoA thiolase: H839_RS09740 phosphoribosyltransferase: aldolase: H839_RS00625 dehydrogenase: H839_RS00625 paraoxon degradation hydrolase: H839_RS16440 H839_RS08340 diphosphatase: H839_RS10615 H839_RS07200 H839_RS18215 [+ 2 isozymes] H839_RS11995 [+ 2 isozymes] isoliquiritigenin H839_RS18085 [+ 2 isozymes] H839_RS13615 6-hydroxymethyl- + NaMN glycolaldehyde a carboxylate an alcohol NADP A(H2) palmitate a retinol Cys 2,3-didehydroadipyl-CoA 7,8-dihydropterin a tRNA cys F6P phosphoenol CMP paraoxon pyruvate enoyl-CoA phosphotriesterase: hydratase: H839_RS05685 H839_RS09480 phosphotriesterase: an N 10 - 4-dihydrocoumaroyl-CoA malonyl-CoA H + an mRNA maltotetraose N-formylkynurenine precorrin-2 Co 2+ 2-deoxy-D-ribose a polypeptide H839_RS10000 formyltetrahydrofolate L-selenocysteine enoyl-CoA maltodextrin diethylphosphate 4-nitrophenol chalcone synthase: formyltetrahydrofolate mRNA arylformamidase: sirohydrochlorin selenocysteine serine protease: hydratase: phosphorylase: ribokinase: H839_RS09740 deformylase: interferase PemK: H839_RS06855 cobaltochelatase: lyase: H839_RS00550 H839_RS10635 H839_RS14625 H839_RS16520 H839_RS08435 H839_RS00660 H839_RS07285 H839_RS08400 phloretin a single- a single- α-D-glucopyranose formate L-kynurenine [+ 2 isozymes] formate a tetrahydrofolate maltotriose cobalt-precorrin-2 2-deoxy-D-ribose 3-hydroxyadipyl-CoA stranded RNA 1-phosphate selenide ala stranded RNA 5-phosphate a polypeptide acetyl-CoA fermentation to butanoate II Carboxylate Degradation superpathway of acetate utilization and formation a DNA containing an RNase R degradation γ-L-glutamyl-(S)- a debranched a single RX α-D-ribofuranose acetyl-CoA substrate RNA an mRNA (S)-dihydroorotate fumarate methyl-L-cysteine glutathione α-limit dextrin 3-oxoadipyl-CoA acetate acetate--CoA ligase: apurinic/apyrimidinic site stranded DNA endonuclease III: ribonuclease R: mRNA dihydroorotate aminopeptidase glutathione maltodextrin H839_RS14080 ribokinase: beta-ketoadipyl H839_RS11165 H839_RS15420 interferase PemK: dehydrogenase: A: H839_RS14950 transferase: phosphorylase: DNA primase: acetyl-CoA phosphotransacetylase: H839_RS16520 CoA thiolase: acetate kinase: acetyl-CoA synthetase: a 3'-terminal a nucleoside 5'- H839_RS00660 H839_RS04540 S-methyl- H839_RS10890 H839_RS14625 H839_RS12680 acetyltransferase: eutD H839_RS14180 a 5'-phosphopolynucleotide a diribonucleotide a single- a single- glt a glutathione- H839_RS10500 H839_RS14280 unsaturated sugar monophosphate succinate orotate L-cysteine HX α-D-glucopyranose α-D-ribose H839_RS05405 stranded RNA stranded RNA S-conjugate a short RNA beta-ketoadipyl [+ 4 isozymes] 1-phosphate 5-phosphate segment acetyl phosphate CoA thiolase: acetyl phosphate acetyl-CoA H839_RS10615 pyruvate fermentation to acetate IV acetoacetyl-CoA acetate kinase: a [histone]-N 6 - a large- H + malonyl-CoA (E)-cinnamoyl-CoA H + isovaleryl-CoA malonyl-CoA coenzyme A NADP + a 1-monoglyceride H O acetyl-CoA α-D-galactose succinyl-CoA H839_RS14180 acetyl-L-lysine sarcosine 2 branched glucan pyruvate chalcone synthase: chalcone synthase: CoA-disulfide histone acylglycerol acetyl-CoA phosphotransacetylase: eutD glycine oxidase: pullulanase: galactokinase: acetate H839_RS09740 H839_RS09740 reductase: deacetylase: lipase: hydrolase: H839_RS02455 H839_RS14385 H839_RS11055 (R)-3- formate H839_RS02315 H839_RS14295 H839_RS07175 H839_RS01630 pinocembrin chalcone 6-isobutyl-4-hydroxy-2-pyrone methylamine glyoxylate hydroxybutanoyl- acetyltransferase: H + NADPH CoA-disulfide acetate a [histone]-L-lysine glycerol a fatty acid acetate a long-linear α-D-galactose CoA H839_RS17575 α-D-glucan 1-phosphate

acetyl-CoA formate a 5S rRNA γ-L-glutamyl-(S 2'-deoxycytidine UTP an N-terminal L- H + 4-coumaryl-CoA malonyl-CoA a ribonucleic acid 5,6-dihydrouracil 2-oleoylglycerol β-D-galactose precursor )-allyl-L-cysteine deoxycytidine glutamyl-[protein] crotonyl-CoA acylglycerol phosphotransacetylase: chalcone synthase: ribonuclease M5: ribonuclease PH: aminopeptidase kinase: aminopeptidase dihydropyrimidine galactose lipase: acyl-CoA eutD H839_RS09740 H839_RS18025 H839_RS13620 A: H839_RS14950 H839_RS17905 A: H839_RS14950 dehydrogenase: mutarotase: a double-stranded a nucleoside H839_RS07175 H839_RS11040 dehydrogenase: 2',4,4',6'-tetrahydroxychalcone a mature 5S-rRNA a ribonucleic acid glt S-allyl-L-cysteine a protein H839_RS05775 oligonucleotide diphosphate UDP dCMP glt H839_RS17435 D-gluconate acetyl phosphate uracil oleate glycerol α-D-galactose [+ 11 isozymes] degradation acetate kinase: butanoyl-CoA D-gluconate H839_RS14180 5,6- 1-oleoyl- 2'-deoxycytidine HMG-CoA sucrose 6-kestotriose canavaninosuccinate a tripeptide sucrose a levan N-ethylglycine dihydrothymine gluconokinase: sn-glycerol deoxycytidine acetate levansucrase: peptidase T: levansucrase: dihydropyrimidine acylglycerol H839_RS06775 hydroxymethylglutaryl-CoA argininosuccinate glycine oxidase: kinase: D-gluconate H839_RS17500 H839_RS07560 H839_RS17500 dehydrogenase: lipase: lyase: H839_RS09485 lyase: H839_RS14065 H839_RS02455 H839_RS17905 6-phosphate D-glucopyranose 6,6-kestotetraose a proteinogenic D-glucopyranose a levan H839_RS05775 H839_RS07175 acetyl-CoA acetoacetate fumarate L-canavanine a dipeptide ethylamine glyoxylate dCMP butanoate amino acid thymine oleate glycerol

glycine D-mannitol phosphate a branched- a branched- a branched- a branched- a branched- a branched- a [PTS betaine daunorubicin 1-phosphate an amino an amino an amino an amino an amino an amino an amino an amino gly lactose 6'- sucrose 6- a C4- glutamate glutamate chain chain chain chain chain chain D-fructose D-fructose D-fructose D-glucose 6- D-glucose 6- a sugar phosphate a sugar phosphate a sugar phosphate a sugar phosphate + enzyme I]- phosphate a dicarboxylate (S)-lactate trehalose an antibiotic D-gluconate ferrichrome a macrolide ammonium ammonium H acid acid acid acid acid acid acid acid glycine betaine phosphate phosphate dicarboxylate amino acid amino acid amino acid amino acid amino acid amino acid 1-phosphate 1-phosphate 1-phosphate phosphate phosphate N-acetyl-β-muramate 6-phosphate N-acetyl-β-muramate 6-phosphate N-acetyl-β-muramate 6-phosphate N-acetyl-β-muramate 6-phosphate L-histidine phosphate predicted predicted predicted ABC predicted ABC PEP-driven ABC RS10185 RS02020 RS10315 RS03680 FliI RS06165 RS00560 RS03475 RS02480 RS15105 RS06675 RS17545 RS05310 RS00840 RS12755 RS14940 RS01075 transporter RS01615 RS01815 RS07945 RS06160 RS17495 transporter of RS02070 RS12935 RS02075 RS05170 RS02710 LivG RS15310 RS16630 RS02715 RS17625 RS16765 RS07075 RS03830 RS17505 RS05860 RS06625 RS06720 RS06155 RS11710 RS17645 transporter transporter of glycine daunorubicin of D-mannitol of phosphate betaine ammonium ammonium H +

a branched- a branched- a branched- a branched- a branched- a branched- a sugar a sugar a sugar a sugar trehalose lactose sucrose daunorubicin a C4- D-fructose D-fructose D-fructose D-glucose D-glucose D-gluconate D-mannitol a β-glucoside an amino an amino an amino an amino an amino an amino an amino an amino gly glycine a dicarboxylate (S)-lactate glutamate glutamate chain chain chain chain chain chain an antibiotic N-acetyl-D-muramate N-acetyl-D-muramate N-acetyl-D-muramate N-acetyl-D-muramate ferrichrome a macrolide phosphate phosphate dicarboxylate acid acid acid acid acid acid acid acid glycine betaine betaine amino acid amino acid amino acid amino acid amino acid amino acid phosphate This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.