Richard J. Schmidt Phd Qualifications Professional Career Summary Publishing / IT Activities
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Richard J. Schmidt PhD Pharmacist ~ Chartered Chemist ~ Intellectual Property Realisation Consultant 117 Andrew Road Penarth CF64 2NW, UK Tel. +44 (0)2920 703865 www.inter--face.org [email protected] ➢➢ Qualifications Jun 1973 BPharm (Hons); Second Class (Upper); University of London Jul 1974 MPS; from 1988: MRPharmS Dec 1977 PhD (Lond.) Apr 1985 FLS Apr 1996 CChem, FRSC Oct 2013 FFRPS Current Professional Registration General Pharmaceutical Council (GPhC) No. 2019451 Royal Society of Chemistry (RSC) No. 0333848 Member of the UK Register of Expert Witnesses (http://www.jspubs.com/Experts/register/reg_index.cfm) ➢➢ ➢➢ Professional Career Summary Jan 2000 – to date Business consultant (intellectual property realisation; patent drafting; EPO patent opposition; medical device / cosmetics product registration; information technology; information retrieval; forensic / expert report / legal brief writing) Sep 1997 – Jan 2000 Senior Research Scientist, Wound Care Research Group, Johnson & Johnson Medical Ltd, Gargrave, UK Apr 1983 – Aug 1997 Honorary Scientific Officer in the Dermatology Department, University Hospital of Wales (now University of Wales College of Medicine) Apr 1979 – Aug 1997 Lecturer, Welsh School of Pharmacy, UWC (formerly UWCC / UWIST) Cardiff Apr 1978 – Mar 1979 Temporary Lecturer, Undergraduate School of Studies in Pharmacy, University of Bradford Dec 1977 – Mar 1978 Superintendent pharmacist in a community pharmacy Jul 1974 – to date Occasional and ongoing work as a locum community pharmacist ➢➢ ➢➢ Publishing / IT Activities Jan 1986 Co-founder of STS Publishing, Welsh School of Pharmacy, UWIST, Cardiff. Allocated the publisher prefix 0-948917 Jun 1986 Published "Child Care Through the Centuries" (Editors Cule J & Turner T) [ ISBN 0-948917-00-8 : http://www.worldcat.org/oclc/17620478 – one of the first books to be typeset using a word processor] Jun 1986 Published "Wound Management in Industry" (Editors Turner T, Cockbill S and Caudwell D) [ ISBN 0-948917-01-6 : http://www.worldcat.org/oclc/17442735 ] 1994 - to date Webmaster: BoDD - Botanical Dermatology Database (http://www.botanical-dermatology- database.info/) 1995 - 1997 IT support (MacOS) / Webmaster: Welsh School of Pharmacy, Cardiff University, UK (http:// info.cf.ac.uk/uwcc/phrmy/) 2000 - to date Webmaster: inter--face.org (http://www.inter--face.org/) 2001 - 2017 Webmaster: Martin Biggs Associates (http://www.mba-gbm.com/ ; http://www.ce-marking- authorized-representative.com/) 2012 - 2018 Webmaster: Pharma Sol International Ltd (http://www.pharma-sol-international.com/) ➢➢ RJ Schmidt ~ Curriculum Vitae ~ February 2018 p !1 of 18! ➢➢ Analytical experience As a undergraduate student in the School of Pharmacy, University of London, I received laboratory instruction in Pharmaceutical Analysis and Pharmacognosy. This provided “hands-on” experience of a variety of techniques including gravimetric, volumetric, acidimetric & alkalimetric, and various spectroscopic and spectrometric methods. We also covered microscopy, titrimetry, aquametry, limit tests, alkaloid determinations, and a variety of other pharmacopoeial quality control / assurance determinations. As a post-graduate research student, I used a variety of analytical techniques commonly applied in the isolation, structure elucidation, and quantification of [toxic] phytochemicals. These included IR & UV-Visible spectroscopy, circular dichroism, nuclear magnetic resonance spectrometry, and mass spectrometry. I also used a variety of chromatographic techniques, both qualitatively and quantitatively, including gas chromatography, high pressure liquid chromatography, thin layer chromatography, and the so-called “hyphenated” technique gas chromatography-mass spectrometry. As a lecturer in the Bradford University school of pharmacy and then in the Welsh School of Pharmacy, I spent about 18 years teaching many of these methods and techniques, the principles underlying their calibration and validation, and the statistical analysis of data produced. I also gave lectures on advanced spectroscopic and spectrometric methods, including the use of Fourier transform in nuclear magnetic resonance spectrometry. I have also applied many of these techniques in my own research and have trained and supervised postgraduate students and research associates seeking to apply these techniques in their research projects. ➢➢ ➢➢ Toxicology experience Pharmaceutical drugs have been described as “selectively toxic agents”; selective toxicity is the basis of molecular pharmacology [see, for example, A. Albert (1985) Selective Toxicity. The physico-chemical basis of therapy. 7th edn. London: Chapman and Hall. http://www.worldcat.org/oclc/924597587]. Pharmacists, whilst understanding how drugs can be used therapeutically, also understand how drugs may cause unwanted (toxic) effects, and also understand the interplay between wanted and unwanted effects when different drugs – which in some patients may number in excess of 20 different drugs – are administered to the same patient. In this sense, pharmacy is a branch of toxicology. During the time I spent lecturing to pharmacy undergraduate students, I was responsible for teaching various aspects of the biochemical toxicology of food plants, poisonous plants, natural products, and pesticides. In addition, my research training involved the isolation and characterisation (and safe handling) of some of the most skin- and mucous membrane-irritant compounds known to man, namely mono-and di-esters of various tigliane, ingenane, and daphnane polyols. Subsequent research took me into the field of allergic contact dermatitis, in which I was involved in the isolation, characterisation (and safe handling) of potent contact allergens, including known carcinogens. Therefore, I am appropriately described as a pharmacist / toxicologist / chemist with a special interest in dermatotoxicology. ➢➢ RJ Schmidt ~ Curriculum Vitae ~ February 2018 p !2 of 18! ➢➢ Forensic experience My forensic experience derives from training I received in forensic methodology in Pharmacognosy and Pharmaceutical Analysis laboratory classes at undergraduate level (1969–1973); the teaching of these skills to undergraduates in the Schools of Pharmacy in Bradford University (1978–1979) and Cardiff University (1979– 1997); my own training in research skills to PhD level (1974–1977); and the experience of training and mentoring numerous postgraduate research students in research methodology and thesis preparation (1980– 2000). Classically, pharmacognosy is that area of pharmacy concerned with the microscopic identification and quality control of crude drugs in powdered form. Many classically-trained pharmacognosists such as myself became involved in legal cases as experts in the identification of substances of abuse such as cannabis and opium. Perhaps the most notable pharmacognosist in the UK in recent times was Professor Frank Fish (http:// www.heraldscotland.com/opinion/13029880.Frank_Fish/) who was not only Dean of the School of Pharmacy from which I graduated but who also established courses in forensic science in both Strathclyde and London. Slide no. 23 from the Second Professor Frank Fish Memorial Award Lecture delivered by Professor A. Douglas Kinghorn (one of my contemporaries) in October 2013 shows a photograph of UK pharmacognosists taken in the late 1970s – see http://www.inter--face.org/pdfs/frankfish2013slides.pdf ; I am standing 5th from the right. Throughout my whole professional career, information retrieval has been essential to my work as a research scientist and university lecturer. In the early days, this involved understanding how published information is structured and stratified in so-called primary, secondary and tertiary paper sources. In recent times, the internet and electronic publication has added a new dimension (“IT”). I was for a while responsible in the Welsh School of Pharmacy for providing training to our undergraduates in information retrieval skills. In addition, my work as a locum community pharmacist, provides daily direct experience of document and signature analysis. Pharmacists are presented with prescriptions, which in the UK can be National Health Service [NHS] or private prescriptions. These are legal documents that have to be written correctly in order to be valid. Some individuals seek to amend their prescriptions prior to presentation at a pharmacy in order to obtain either greater quantities or greater strengths of certain drugs of abuse. Occasionally, pads of prescriptions are stolen. When this occurs, the signature of the physician is also then forged. So, on being presented with a prescription, the first task of every community pharmacists is to ascertain whether the prescription is validly written, signed by the prescriber, and unaltered. A reward is offered to pharmacies in the NHS for each fraudulent prescription detected. So, document examination can be regarded as a generic skill possessed to a greater or lesser extent by every community pharmacist, and especially by those such as myself who spent many years dispensing hand-written prescriptions in the days before the widespread adoption of modern computer technology. According to Paragraph 9. (1) (a) in Part 2 of the National Health Service (Pharmaceutical and Local Pharmaceutical Services) Regulations 2013 [see page 141 in http://www.legislation.gov.uk/uksi/2013/349/pdfs/ uksi_20130349_en.pdf]: "A pharmacist may refuse to provide drugs or appliances ordered on a prescription form … where the pharmacist reasonably