Withdrawal Reflex B

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Withdrawal Reflex B Spinal Cord Lec: 4 Assis.Professor Dr. Farah Nabil Abbas MBChB, MSc, PhD Golgi Tendon Organs Encapsulated sensory receptors. Located in tendons near their junction with the muscle. 10-15 muscle fibers are connected in series with each Golgi tendon organ. Endings of afferent nerve fibers wrapped around collagen bundles in tendon. Golgi Tendon Organs Contraction of attached extrafusal muscle fibers pull on the tendon straightens collagen bundles distorts receptor endings activating their afferent neurons Transmission of APs to CNS via type Ib nerve fibers. • Inhibit via interneurons, of motor neurons to contracting muscle and its synergists. • Stimulate motor neurons of antagonistic muscles. Inverse Stretch Reflex Sense Organ Golgi tendon organ Afferent Neuron Ib fiber Synapse CNS (spinal cord) Efferent Neuron Alpha Motor Neuron Effector Muscle (extrafusal muscle) Importance 1. Prevent muscle tearing or tendon avulsion from its attachments to the bone. 2. Equalize contractile forces of separate muscle fibers (fibers which exert excess tension become inhibited by the reflex spread muscle load over all fibers prevent damage in isolated areas of a muscle where small numbers of fibers might be overloaded Polysynaptic Reflexes A. Withdrawal reflex B. Crossed-extensor reflex. C. Abdominal reflex D. Cremasteric reflex Withdrawal Reflex Cutaneous sensory stimuli on a limb contraction of flexor muscles withdrawing limb “flexor reflex" or "nociceptive reflex" or "pain reflex". Polysynaptic reflex A. Contraction of flexor muscles B. Inhibition of extensor muscles. Crossed Extensor Reflex Application of strong stimulus to a limb. Response includes: A. Flexion and withdrawal of that limb B. Extension of the opposite limb after 0.2- 0.5 second. Abdominal Reflex Superficial reflex Thoracic 7th -12th segments Polysynaptic Subject lie down in the supine position. Gently stroke abdominal skin from lateral to medial aspect in all four quadrant → abdominal muscles contract → umbilicus deviate towards the area stimulated. Absent Abdominal reflex 1. Physiological (obesity, tolerance, children, multiparous lax abdominal wall). 2. Pathological: Multiple Sclerosis Motor Neuron Disease Neurogenic Bladder Brown-Séquard syndrome Chiari Malformations Cremaasteric Reflex Area A (orange): area of sensory fibers controlled by the genitofemoral nerve Area B (green): area of sensory fibers controlled by the ilioinguinal nerve Arrow C (red): direction and location where the skin must be stroked to elicit this reflex. Functions of Stretch Reflex 1) Skeletal Muscle Tone: • Maintenance of erect posture against force of gravity, by producing a strong muscle tone in the antigravity muscle. 2) Damping (smoothing) function: • Signals discharged to a muscle often have varying intensities irregular movements. However through muscle spindle and alpha-gamma linkage, signal are adjusted to produce smooth movements. Functions of Stretch Reflex 3) Servo-Assist Function: servo = force regulator: • Stretch reflex assists the brain to produce and regulate force of muscle contraction as follow when the muscle contract: I. α and γ motor fibers are activated to same degree. II. Extrafusal & intrafusal muscle fibers equally contracted and shortened to same degree. III. Central part of intrafusal muscle fibers does not change, and intensity of stretch receptor remains unchanged. Functions of Stretch Reflex iv. If the muscle tries to left a heavy weight, extrafusal fiber contract isometrically and intrafusal fibers contract at the periphery and lengthen central part. v. Potentiates stretch reflex leading to strong muscle contraction to help lifting the weight. 4) Antigravity Function: • To resist gravity effect which tends to flex muscle of lower limbs and trunk. Stretched muscles respond by reflex contraction to maintain upright position of body and prevent its fall down. Dorsal Sensation Arrival of Activation of a root relayed to stimulus and sensory neuron the brain by activation of collateral receptor REFLEX Receptor ARC Stimulus Effector Ventral root Information processing in CNS Response Activation of a by effector motor neuron KEY Sensory neuron (stimulated) Excitatory Reflex Action interneuron Motor neuron (stimulated) Stretching of muscle tendon stimulates muscle spindles Muscle spindle (stretch receptor) Stretch Spinal cord REFLEX ARC Contraction Activation of motor neuron produces reflex muscle contraction .
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