Coma Deep Tendon Reflexes Definition
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Focusing on the Re-Emergence of Primitive Reflexes Following Acquired Brain Injuries
33 Focusing on The Re-Emergence of Primitive Reflexes Following Acquired Brain Injuries Resiliency Through Reconnections - Reflex Integration Following Brain Injury Alex Andrich, OD, FCOVD Scottsdale, Arizona Patti Andrich, MA, OTR/L, COVT, CINPP September 19, 2019 Alex Andrich, OD, FCOVD Patti Andrich, MA, OTR/L, COVT, CINPP © 2019 Sensory Focus No Pictures or Videos of Patients The contents of this presentation are the property of Sensory Focus / The VISION Development Team and may not be reproduced or shared in any format without express written permission. Disclosure: BINOVI The patients shown today have given us permission to use their pictures and videos for educational purposes only. They would not want their images/videos distributed or shared. We are not receiving any financial compensation for mentioning any other device, equipment, or services that are mentioned during this presentation. Objectives – Advanced Course Objectives Detail what primitive reflexes (PR) are Learn how to effectively screen for the presence of PRs Why they re-emerge following a brain injury Learn how to reintegrate these reflexes to improve patient How they affect sensory-motor integration outcomes How integration techniques can be used in the treatment Current research regarding PR integration and brain of brain injuries injuries will be highlighted Cases will be presented Pioneers to Present Day Leaders Getting Back to Life After Brain Injury (BI) Descartes (1596-1650) What is Vision? Neuro-Optometric Testing Vision writes spatial equations -
The Grasp Reflex and Moro Reflex in Infants: Hierarchy of Primitive
Hindawi Publishing Corporation International Journal of Pediatrics Volume 2012, Article ID 191562, 10 pages doi:10.1155/2012/191562 Review Article The Grasp Reflex and Moro Reflex in Infants: Hierarchy of Primitive Reflex Responses Yasuyuki Futagi, Yasuhisa Toribe, and Yasuhiro Suzuki Department of Pediatric Neurology, Osaka Medical Center and Research Institute for Maternal and Child Health, 840 Murodo-cho, Izumi, Osaka 594-1101, Japan Correspondence should be addressed to Yasuyuki Futagi, [email protected] Received 27 October 2011; Accepted 30 March 2012 Academic Editor: Sheffali Gulati Copyright © 2012 Yasuyuki Futagi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The plantar grasp reflex is of great clinical significance, especially in terms of the detection of spasticity. The palmar grasp reflex also has diagnostic significance. This grasp reflex of the hands and feet is mediated by a spinal reflex mechanism, which appears to be under the regulatory control of nonprimary motor areas through the spinal interneurons. This reflex in human infants can be regarded as a rudiment of phylogenetic function. The absence of the Moro reflex during the neonatal period and early infancy is highly diagnostic, indicating a variety of compromised conditions. The center of the reflex is probably in the lower region of the pons to the medulla. The phylogenetic meaning of the reflex remains unclear. However, the hierarchical interrelation among these primitive reflexes seems to be essential for the arboreal life of monkey newborns, and the possible role of the Moro reflex in these newborns was discussed in relation to the interrelationship. -
Brainstem Dysfunction in Critically Ill Patients
Benghanem et al. Critical Care (2020) 24:5 https://doi.org/10.1186/s13054-019-2718-9 REVIEW Open Access Brainstem dysfunction in critically ill patients Sarah Benghanem1,2 , Aurélien Mazeraud3,4, Eric Azabou5, Vibol Chhor6, Cassia Righy Shinotsuka7,8, Jan Claassen9, Benjamin Rohaut1,9,10† and Tarek Sharshar3,4*† Abstract The brainstem conveys sensory and motor inputs between the spinal cord and the brain, and contains nuclei of the cranial nerves. It controls the sleep-wake cycle and vital functions via the ascending reticular activating system and the autonomic nuclei, respectively. Brainstem dysfunction may lead to sensory and motor deficits, cranial nerve palsies, impairment of consciousness, dysautonomia, and respiratory failure. The brainstem is prone to various primary and secondary insults, resulting in acute or chronic dysfunction. Of particular importance for characterizing brainstem dysfunction and identifying the underlying etiology are a detailed clinical examination, MRI, neurophysiologic tests such as brainstem auditory evoked potentials, and an analysis of the cerebrospinal fluid. Detection of brainstem dysfunction is challenging but of utmost importance in comatose and deeply sedated patients both to guide therapy and to support outcome prediction. In the present review, we summarize the neuroanatomy, clinical syndromes, and diagnostic techniques of critical illness-associated brainstem dysfunction for the critical care setting. Keywords: Brainstem dysfunction, Brain injured patients, Intensive care unit, Sedation, Brainstem -
Neurologic AESI Glossary of Terms
Neurologic AESI Glossary of Terms Includes terms for the following Brighton Collaboration Case Definitions: • Encephalitis, myelitis, acute disseminated encephalomyelitis • Guillain Barré and Miller Fisher Syndromes • Peripheral Facial Nerve Palsy (Bell’s palsy) • Aseptic meningitis • Generalized convulsion Acalculia: inability to perform simple mathematical tasks (addition, subtraction, multiplication) Agnosia: inability to recognize objects or persons Agraphesthesia: difficulty recognizing a written number or letter traced on the palm of the hand Agraphia: impairment in the ability to write AIDP: acute inflammatory demyelinating polyneuropathy (most common form of GBS) Alexia: impairment of ability to read AMAN: acute motor axonal neuropathy (a less common form of GBS) AMSAN: acute motor and sensory axonal neuropathy (a less common form of GBS) Aphasia / Dysphasia: impairment of spoken language abilities that affect production and/or comprehension of speech. Apraxia: inability to execute purposeful movements Aprosodia: decreased ability to generate or comprehend emotion as conveyed in spoken language Asterognosia: inability to identify an object by active touch of the hands without other sensory input (e.g. visual) Ataxia: loss of coordination in voluntary movements; can present in many ways including: lack of coordination, slurred speech, gait abnormalities, inability to balance, trouble eating and swallowing, loss of fine motor skills, tremors; Atonic motor manifestations: sudden loss in tone of postural muscles; may be preceded by -
Cortex Brainstem Spinal Cord Thalamus Cerebellum Basal Ganglia
Harvard-MIT Division of Health Sciences and Technology HST.131: Introduction to Neuroscience Course Director: Dr. David Corey Motor Systems I 1 Emad Eskandar, MD Motor Systems I - Muscles & Spinal Cord Introduction Normal motor function requires the coordination of multiple inter-elated areas of the CNS. Understanding the contributions of these areas to generating movements and the disturbances that arise from their pathology are important challenges for the clinician and the scientist. Despite the importance of diseases that cause disorders of movement, the precise function of many of these areas is not completely clear. The main constituents of the motor system are the cortex, basal ganglia, cerebellum, brainstem, and spinal cord. Cortex Basal Ganglia Cerebellum Thalamus Brainstem Spinal Cord In very broad terms, cortical motor areas initiate voluntary movements. The cortex projects to the spinal cord directly, through the corticospinal tract - also known as the pyramidal tract, or indirectly through relay areas in the brain stem. The cortical output is modified by two parallel but separate re entrant side loops. One loop involves the basal ganglia while the other loop involves the cerebellum. The final outputs for the entire system are the alpha motor neurons of the spinal cord, also called the Lower Motor Neurons. Cortex: Planning and initiation of voluntary movements and integration of inputs from other brain areas. Basal Ganglia: Enforcement of desired movements and suppression of undesired movements. Cerebellum: Timing and precision of fine movements, adjusting ongoing movements, motor learning of skilled tasks Brain Stem: Control of balance and posture, coordination of head, neck and eye movements, motor outflow of cranial nerves Spinal Cord: Spontaneous reflexes, rhythmic movements, motor outflow to body. -
Physiology and Pathophysiology 2018/2019 Dental Medicine Examination Synopsis in Physiology
Medical University of Varna Department of Physiology and Pathophysiology 2018/2019 Dental medicine Examination Synopsis in Physiology Theoretical exam 1. Homeostasis. Control systems of the body – characteristics. Negative feedback mechanism. 2. Cell membranes. Transport of substances through cell membranes. 3. Membrane potential. Resting membrane potential of nerves. 4. Nerve action potential. Propagation of the action potential. Conduction velocity. 5. Signal transmission in nerve fibers. Excitation - the process of eliciting the action potential. Threshold for excitation, refractory period. Inhibition of excitability. 6. Organization and functions of the nervous system. Types of synapses. Electrical synapses. 7. Characteristics of transmission in chemical synapses. 8. Synaptic transmitters. Membrane receptors. 9. Generation of postsynaptic potentials. Generation of action potentials in the axon. Neuronal inhibition - types. Neuroglia. 10. Characteristics of postsynaptic potentials. Spatial and temporal summation in neurons. "Facilitation" of neurons. Characteristics of synaptic transmission. 10. Transmission and processing of signals in neuronal circuits. Convergence, divergence, reverberating circuits. Reflexes - types. 11. Organization of the autonomic nervous system. Location of autonomic ganglia. Characteristics of sympathetic and parasympathetic function - transmitters. 12. Characteristics of sympathetic and parasympathetic function - receptors. 13. Sympathetic or parasympathetic tone. Denervation effects. Autonomic reflexes. -
Neuropsychiatry Block Stretch Reflex and Golgi Tendon Reflex
NeuroPsychiatry Block Stretch reflex and Golgi Tendon Reflex By Prof. Faten zakareia Physiology Department , College of Medicine , King Saud University 2017 Email: [email protected] Ext:52736 NeuroPsychiatryBlock Motor Functions of the Spinal Cord, The cord Reflexes Chapter 55 (Guyton & Hall) -Reference book/Ganong review of medical physiology • Objectives: Upon completion of this lecture, students are expected to : - Describe the stretch reflex and ts icomponents - Describe the structure and function of the muscle spindle - Differentiate between primary and secondary afferent fibres of muscle spindle, Intrafusal nuclear bag &nuclear chain fibers - Differentiate between the Dynamic gamma efferent and Trail endings discharge and their functional role - Differentiate between static and dynamic stretch reflex& damping mechanism - Describe muscle tone and its abnormalities - Disscuss spinal and supraspinal regulation of the stretch reflex - Describe the components of the inverse stretch reflex (golgi tendon reflex)and its function THE STRETCH REFLEX REFLEX STRETCH (MYOTACTIC) REFLEX https://musom.marshall.edu/anatomy/grosshom/allppt/pdf/Spinalreflexes.pdf CLINICAL TEST | RAPID STRETCH OF MUSCLE (TAP ON MUSCLE TENDON) STIMULUS RESPONSE STRETCHED MUSCLE CONTRACT RAPIDLY (I.E. KNEE JERK) SENSORY MUSCLE SPINDLE PRIMARY RECEPTOR SYNAPSES MONOSYNAPTIC INVOLVED EFFECTS ON CONTRACTS (+) SAME MUSCLE AND SYNERGISTIC MUSCLES MUSCLE OTHER EFFECTS RELAXES (-) ANTAGONISTIC MUSCLE FUNCTION AIDS IN MAINTAINING POSTURE, AVOID MUSCLE RUPTURE,COUNTERS SUDDEN -
Development of the Flexion Withdrawal Reflex
Spinal sensory processing in the human infant: Development of the flexion withdrawal reflex Laura Louise Cornelissen Thesis submitted for the degree of Doctor of Philosophy University College London 2011 1 Declaration The work in this thesis was conducted in the Department of Neuroscience, Physiology and Pharmacology at University College London, and in the Elizabeth Anderson and Obstetrics Wing at University College Hospital. I, Laura Louise Cornelissen, confirm that the work presented in this thesis is my own. Where other information has been derived from other sources, I confirm that this has been indicated in the thesis. Laura Louise Cornelissen March 2011 2 Abstract Immature spinal sensory reflexes have lower mechanical thresholds and are poorly coordinated and exaggerated compared to adult reflexes. However, little quantitative data is available on how these spinal sensory circuits develop in the human infant. This thesis investigates the development of cutaneous flexion withdrawal reflexes in preterm and full- term human infants following noxious and non-noxious stimulation of the heel, and tests whether flexion withdrawal reflex activity is modulated by the commonly administered analgesic, oral sucrose, in a randomised controlled trial. The studies were undertaken in infants aged 28-45 weeks gestation (GA), in-patients at University College Hospital, London. The noxious stimulus was a clinically required heel lance; non-noxious stimulation was either a light touch of the heel or application of calibrated von Frey hairs to the heel. Flexion withdrawal reflex activity was recorded with surface EMG electrodes placed over the biceps femoris muscle. Video recordings of facial expression were recorded for clinical pain assessment. -
Brainstem Dysfunction in Critically Ill Patients
Benghanem et al. Critical Care (2020) 24:5 https://doi.org/10.1186/s13054-019-2718-9 REVIEW Open Access Brainstem dysfunction in critically ill patients Sarah Benghanem1,2 , Aurélien Mazeraud3,4, Eric Azabou5, Vibol Chhor6, Cassia Righy Shinotsuka7,8, Jan Claassen9, Benjamin Rohaut1,9,10† and Tarek Sharshar3,4*† Abstract The brainstem conveys sensory and motor inputs between the spinal cord and the brain, and contains nuclei of the cranial nerves. It controls the sleep-wake cycle and vital functions via the ascending reticular activating system and the autonomic nuclei, respectively. Brainstem dysfunction may lead to sensory and motor deficits, cranial nerve palsies, impairment of consciousness, dysautonomia, and respiratory failure. The brainstem is prone to various primary and secondary insults, resulting in acute or chronic dysfunction. Of particular importance for characterizing brainstem dysfunction and identifying the underlying etiology are a detailed clinical examination, MRI, neurophysiologic tests such as brainstem auditory evoked potentials, and an analysis of the cerebrospinal fluid. Detection of brainstem dysfunction is challenging but of utmost importance in comatose and deeply sedated patients both to guide therapy and to support outcome prediction. In the present review, we summarize the neuroanatomy, clinical syndromes, and diagnostic techniques of critical illness-associated brainstem dysfunction for the critical care setting. Keywords: Brainstem dysfunction, Brain injured patients, Intensive care unit, Sedation, Brainstem -
The Phenomenon of Multiple Stretch Reflexes
Henry Ford Hospital Medical Journal Volume 34 Number 1 Article 6 3-1986 The Phenomenon of Multiple Stretch Reflexes Robert D. Teasdall Follow this and additional works at: https://scholarlycommons.henryford.com/hfhmedjournal Part of the Life Sciences Commons, Medical Specialties Commons, and the Public Health Commons Recommended Citation Teasdall, Robert D. (1986) "The Phenomenon of Multiple Stretch Reflexes," Henry Ford Hospital Medical Journal : Vol. 34 : No. 1 , 31-36. Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol34/iss1/6 This Article is brought to you for free and open access by Henry Ford Health System Scholarly Commons. It has been accepted for inclusion in Henry Ford Hospital Medical Journal by an authorized editor of Henry Ford Health System Scholarly Commons. The Phenomenon of Multiple Stretch Reflexes Robert D. Teasdall, MD* Multiple stretch reflexes occur in muscles adjacent to or remote from the tap. The response may be ipsilateral or bilateral. These reflexes are encountered not only in normal subjects with brisk stretch reflexes but particularly in patients with lesions of the upper motor neuron. The concussion obtained by the blow is conducted along bone to muscle. Muscle spindles are stimulated, and in this manner independent stretch reflexes are produced in these muscles. This mechanism is responsible for the phenomenon of multiple stretch reflexes. The thorax and pelvis play important roles in the contralateral responses by transmitting these mechanical events across the midline. (Henry FordHosp Med J 1986;34:31-6) ontraction of muscles remote from the site of f)ercussion is Head and neck Cencountered in patients with brisk stretch reflexes. -
Spinal Reflexes Marte Rydland a Reflex Is a Protective Response to Stimulus That Does Not Require Conciousness Reflexes
Spinal reflexes Marte Rydland A reflex is a protective response to stimulus that does not require conciousness Reflexes Elements of a reflex arc: 1. Receptor 2. Afferent pathway 3. Integration center 4. Efferent pathway 5. Effector Types of reflexes 1. Stretch reflex → Protects from overstretching 2. Golgi tendon reflex → Protects from over contracting 3. Withdrawal reflex → Protects from potentially harmful stimuli Muscle fibers Types of muscle fibers Extrafusal fibers Intrafusal fibers ▪ Outer layer ▪ Encapsulated in sheaths to form ▪ Provide the force for muscle muscle spindle contraction ▪ Innervated by ɣ-motoneurons ▪ Most of skeletal muscle ▪ Smaller than extrafusal fibers ▪ Innervated by ⍺-motoneurons ▪ Too small to generate force ▪ Attach to tendons ▪ Sensory receptors: Detect the stretch of a muscle Intrafusal fibers – Muscle spindle Nuclear bag fibers Nuclear chain fibers • Have nuclei collected in a "bag" • Have nuclei arranged in series region • Are more numerous than nuclear • Onset of stretch bag fibers • Dynamic changes = LENTGH & • Sustained stretch VELOCITY • Static changes = LENGTH • Annulospiraling endings • Flower spray endings • Innervated by group Ia afferents • Innervated by group Ia + II SLOW afferents RAPID RAPID Renshaw inhibition • Inhibitory interneurons • Between LMN/AMN’s • Negative feedback loop • Removes “noise” • Prevents hyperactive muscle contraction How to move a limb? • Antagonizing muscles must do the opposite • Flexors vs. extensors • Reciprocal innervation • Inhibiting interneurons 1. Stretch reflex (myotatic reflex) Stimulus: stretching of the muscle 1. Intrafusal fiber 2. Type Ia sensory fiber (afferent nerve) 3. Monosynaptic 4. α motor neurons (efferent nerve) 5. Extrafusal muscle fibers = Agonist muscle contracts = Antagonist relaxes Knee jerk reflex 2. Golgi tendon reflex (inverse stretch) Stimulus: contraction of the muscle 1. -
Understanding the Impact of Retained Reflexes on Relationships and Development a Guide for the Infant Mental Health Practitioner
Understanding the Impact of Retained Reflexes on Relationships and Development A Guide for the Infant Mental Health Practitioner Pamela Crljenica, LMSW, IMH-E® (III) Ledges Wellness LLC [email protected] Michigan State University School of Social Work Faculty Workshop Description The field of Infant Mental Health has long understood the critical importance of the infant- parent relationship to all learning and development. But, what if something is interfering with that relationship that the field has yet to recognize? What does it mean for development if a child's or parent’s primitive reflexes, specifically Fear Paralysis and Moro, are still retained? And, how does this impact their ability to build a successful relationship? In this workshop, learn how to identify if these reflexes are retained and impacting attachment, and what you as an Infant Mental Health practitioner can do about it. Objectives Identify specific symptoms of inappropriately active (i.e., retained) Fear Paralysis and Moro reflexes. Learn and apply several relationship- based strategies that encourage integration of the Fear Paralysis and Moro reflexes. What are Primitive Reflexes? Can also be known as primary, infant, or newborn reflexes Innate movement patterns that emerge in- utero Originate in the brainstem or spinal cord Activated through the birthing process (cardinal movements) A predetermined patterned movement response triggered by a sensory stimulation Happens automatically without conscious effort or will What do Primitive Reflexes do? Start a developmental process in the brain and central nervous system Help babies during the birth process and orient them to their new environment after birth Prepares newborn to move against gravity and teaches muscles to move together Gradually lead to voluntary movement (i.e., transforms into adult postural and defensive reflexes) Simply put… Primitive reflexes are the blueprint for movement.