7Th Meeting of the German-Endocrine-Brain-Immune
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7th Meeting of the German-Endocrine-Brain-Immune-Network Frankfurt, July 8-11, 2009 Dear Colleagues, The 7th GEBIN Symposium will be held in Frankfurt a.M. between July 8th-11th, 2009. This year it will be a joint meeting with the Ger- minal Center Conference (GCC). The GCC meeting will be between July 5-9, 2009. According to the overall aim of the GEBIN, this meeting will provide an exciting and interdisciplinary program covering various fields including anatomy, dermatology, endocrinology, ethology, immunology, neurol- ogy, pharmacology, psychiatry, psychology, and zoology. The GEBIN meeting is supported by the two International societies of International Society of Neuroimmunomodulation and PsychoNeuroImmunology Re- search Society. The Symposium will be divided into several thematic sessions. Each session consisting of short oral presentations will be opened with an introductory lecture of an internationally recognized expert in the re- spective field. All contributions will be published in an issue of Brain Behavior and Immunity. The organizers of the GEBIN Symposium 2009 are proud to offer again an Educational Short Course for students. This course will be held prior to the official start of the GEBIN meeting, and is intended to present aspects of Behavior-Neuro-Endocrine-Immune interactions on a scholarly level. We would highly appreciate your participation in this exciting meeting and look forward to welcoming you in Frankfurt in July 2009. With kind regards Rainer H. Straub, GEBIN 15 Local Organizing Committee Rainer H. Straub and team, for GEBIN Silvia Capellino Alexander Faßold Stefanie Haas Torsten Lowin Georg Pongratz Christine Wolff Scientific Committee Prof. Dr. P.C. Arck, Berlin Prof. Dr. H.O. Besedovsky, Marburg Prof. Dr. M. B¨ohm,M¨unster Prof. Dr. J. Born, L¨ubeck Prof. Dr. A. del Rey, Marburg Dr. H. Engler, Essen Dr. B. Fiebich, Freiburg Prof. Dr. R. Gold, Bochum Prof. Dr. V. H¨ollt,Magdeburg PD Dr. J. Kraus, Magdeburg Dr. T. Lange, L¨ubeck Prof. Dr. N. M¨uller,M¨unchen Prof. Dr. M. Schedlowski, Essen PD Dr. M. Schwarz, M¨unchen Prof. Dr. G.K. Stalla, M¨unchen PD Dr. V. Stefanski, Berlin Prof. Dr. R.H. Straub, Regensburg Prof. Dr. E. Weihe, Marburg Abstract quality estimation was performed by all members of the sci- entific committee using a metric system similar to a visual analog scale. The mean value of the estimation score was calculated to find the best 5 abstracts, which will be presented on Thursday afternoon (16:30). 16 Information Further information about the GEBIN and the GEBIN 2009 meeting can be found on the GEBIN homepage: www.gebin.org Coffee Breaks and Lunch Coffee, lunch and refreshments will be available in the foyer (ground level) and in the Mensa of the Campus Westend. Main Sponsors / Exhibitors Biozol Frankfurt Institute for Advanced Studies (FIAS) EU-NEST-project MAMOCELL within FP6 (http://fias.uni-frankfurt.de/ immunology/RESEARCH/mamocell.html) Merck Serono Millipore Roche Supported by Deutsche Forschungsgemeinschaft Deutsche Anatomische Gesellschaft Deutsche Dermatologische Gesellschaft Deutsche Ethologische Gesellschaft Deutsche Gesellschaft f¨urBiologische Psychiatrie Deutsche Gesellschaft f¨urEndokrinologie Deutsche Gesellschaft f¨urImmunologie Deutsche Gesellschaft f¨urMedizinische Psychologie Deutsche Gesellschaft f¨urNeurologie Deutsche Gesellschaft f¨urPharmakologie Deutsche Gesellschaft f¨urPsychologie Deutsche Gesellschaft f¨urZoologie 17 PsychoNeuroImmunology Research Society (PNIRS) International Society of Neuroimmunomodulation (ISNIM) The European Neuropeptide Club World Psychiatric Association, Section Immunology and Psychiatry Acknowledgements The organizers are grateful for expert assistance to: Angelika Gr¨aber Madlen Melzer Margit N¨utzel Luise Rauch Olga Wiesner all from the University Hospital Regensburg, Dept. of Internal Medicine 18 Affiliation Abt.zinische Mikrobiologie, f¨ur Bernhard-Nocht- Institut Immunologie f¨urTropenmedizin, Hamburg undInst. Medi- ofPhilipps Physiology University, and Marburg Pathophysioloy, Dept. of Hygiene andogy, University Medical of Microbiol- Heidelberg Division of Rheumatology,University Hospital, JW Frankfurt am Goethe- Main 19 Speaker Thomas Jacobs Adriana del Rey Alexander Dalpke Matthias Wahle Introduction Infectious diseases in today’s world Title INEI and infectious diseases coffee break Development ofmune diseases autoim- INEI and autoimmunity lunch break Time 09:00-09:15 09:15-10:00 10:00-10:45 10:45-11:15 12:00-12:45 12:45-13:30 11:15-12:00 Wednesday July 8th, 2009 9am - 6:30pm EducationalOrganizer: Short Adriana del Course Rey Location: Eisenhower Conference Room, IG Farben Building, Campus Westend of the JW Goethe-University Affiliation Neurologischesit¨atsklinikumGiessen und Marburg Klinik,Neuroimmunologisches Labor,ogische Neurol- KlinikBochum Univer- der Ruhr-Universitaet, Klinikum Ingolstadt, Zentrumschische Gesundheit, f¨urpsy- Ingolstadt Laborsektion PsychoNeuroImmunologie, Klinik PsychiatrieM¨unchen und Psychotherapie, 20 Speaker Prof. Dr. Richard Dodel Dr. Ralf Linker Prof. Dr. Thomas Pollm¨acher PD Dr. Markus Schwarz Title The basis ofcal central disease neurologi- INEI and neuroimmunology coffee break The most commondiseases psychiatric INEI and psychiatric diseases coffee break Discussion with the Students Time 14:15-15:00 15:00-15:30 16:15-17:00 17:00-17:30 15:30-16:15 17:30-18:30 13:30-14:15 Wednesday July 8th, 2009 9am - 6:30pm EducationalOrganizer: Short Adriana del Course Rey 8pm Trainee Dinner (only for participating students) (Organized jointly with the GCC) -Bungarotoxin nicotine type of acetylcholine receptor on α 21 Title Role of the nervous systemAnalysis in of the arthritis molecularcircadian clock rhythm in of CD4+ T CD4+ cells T and cells Germinal its centre relevance innervation for of the bovine functional andNerve human Growth tonsils Factor: related a to candidate prion forbreak diseases airway remodeling? Regulatory mechanisms of chronic inflammatoryCannabinoid pain and opioid-mediated increasetriggered signaling in cyclic AMP inhibitsA T new cell role receptor- dermatitis? for the spleen asSuppression a of IL-6 conductor productionhigh of from expression neuro-immune cholinergic of regulation stimulatedCD14+ non PBMS cells in is allergic connected to Beta-adrenoceptor stimulation inhibitsPKA- calcineurin dependent in pathway CD4+ T lymphocyteslunch via a Cobi J. Heijnen Rainer H. Straub 09:3509:5510:15 Thomas Bollinger 10:35 Ernst Heinen 11:05 Ayse Kilic 11:4012:00 J¨urgenKraus 12:20 Christiane Liezmann 12:40 Olga Malysheva 13:00 Carsten Riether Time Page09:00 Speaker Thursday July 9th, 2009 9am - 1pm Peripheral Neuroimmune Interactions, Part 1 Chairs: Cobi J. Heijnen, Rainer H. Straub 22 Title Neuroimmunology and Neuroprotection Altered affective behavior infactors a model of multipleSignificant sclerosis: impact elevation of(MIF) of neurotrophic and CD14 serum -(MMS) Sign levels in for over-stimulation schizophrenia of of the monocytes/macrophages-system macrophage-migration-inhibitory-factor The mood stabilizerpression: valproic cenral acid role oftreatment down nuclear regulates factor-kappa B neuronal after cyclooxygenase-2 longSecondary term, ex- lymphoid but tissue not chemokine short- (CCL21) term T-cell in neuron-microglia alterations signaling indisorders CSF and peripheral bloodAssociation in between Chlamydophila patients infections with and neuropsychiatric schizophrenia break Ralf A. Linker 14:3514:50 Isabella Peruga 15:05 Larissa de la Fontaine 15:20 Vikramjeet Singh 15:3515:50 Knut Biber 16:05 Horst-G Maxeiner Barbara Fellerhoff Time Page Speaker 14:00 Thursday July 9th, 2009 2pm - 4:05pm NeuroimmunologyChairs: Related Ralf to Gold, the Bernd CNS Fiebig, Ralf A. Linker 23 Title The SNS promotesarthritis the development of BLocal cells catecholamine production that andtherapy? synovial show inflammation: regulatory new potential target for in arthritis Destruction of brainstem noradrenergic neurons affectsSubclinical splenic depressive cytokine production symptomslevels are associated with galectin-1PTSD: Changes and in interleukin-6 interplay signal transduction pathways central tobreak the endocrine-immune 16:5017:1017:30 Silvia Capellino Harald Engler 17:50 Sven Benson 18:15 Jutta M. Wolf Time Page Speaker 16:30 Georg Pongratz Thursday July 9th, 2009 4:30pm - 6:10pm TopChairs: Contributions Markus Session B¨ohm,Hugo (best O. Besedosvky abstracts) 24 Title Regulatory T cellstoimmune and disease the sympathetic nervous systemInterception in of a repulsion factors: murine model aTropisetron of possible - treatment au- a of novel rheumatoid antifibrotic arthritis? agent Melanocortin peptides and derivatives - emergingUremic antifibrotic pruritus: therapeutic Characterization tools of clinicalCortisol, and steroid immunohistological parameter hormonesand and adhesion cannabinoids to fibronectin influence in integrinCortisol synovial alpha5 and fibroblasts epinephrine expression differentiallycytes influence CXCR4+ and CX3CR1+ lympho- Time Page Speaker 18:30 Timo Wirth 18:4519:0019:15 Alexander Faßold 19:30 Agatha Kokot 19:45 Markus B¨ohm Ngoc Quan20:00 Phan Torsten Lowin Tanja Lange Thursday July 9th, 2009 6:30pm - 8:15pm PeripheralChairs: Neuroimmmune Harald Interaction, Engler, Part Georg 2 Pongratz 25 Title An activated inflammatory responsement system of as major co-factor psychiatric for the diseases Tryptophan develop- metabolism and immunogenetics in majorInterleukin-2 depression reducesrelated extracellular behaviour in cortical the forced serotonin swimThe test and impact in of increases