Anti-SETMAR (full length) polyclonal antibody (DPABH-06532) This product is for research use only and is not intended for diagnostic use.
PRODUCT INFORMATION
Antigen Description Histone methyltransferase that methylates Lys-4 and Lys-36 of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 Lys-36. Has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5-terminal inverted repeats (TIRs) of the Hsmar1 element. Has DNA nicking activity. Has in vivo end joining activity and may mediate genomic integration of foreign DNA.
Immunogen Recombinant full length protein, corresponding to amino acids 1-352 of Human SETMAR (AAH11635.1; UniProt Q53H47-2).
Isotype IgG
Source/Host Mouse
Species Reactivity Human
Purification Protein A purified
Conjugate Unconjugated
Applications WB
Format Liquid
Size 50 μg
Buffer pH: 7.20; Constituent: 99% PBS
Preservative None
Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
GENE INFORMATION
Gene Name SETMAR SET domain and mariner transposase fusion gene [ Homo sapiens ]
Official Symbol SETMAR
Synonyms SETMAR; SET domain and mariner transposase fusion gene; histone-lysine N-
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved methyltransferase SETMAR; metnase; hsMar1; SET domain and mariner transposase fusion gene-containing protein; METNASE;
Entrez Gene ID 6419
Protein Refseq NP_001230652
UniProt ID Q53H47
Chromosome Location 3p26.2
Pathway Lysine degradation;
Function endonuclease activity; histone-lysine N-methyltransferase activity; hydrolase activity; metal ion binding; methyltransferase activity; protein binding; protein homodimerization activity
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved