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(12) United States Patent (10) Patent No.: US 9,011,834 B1 Mckenzie Et Al

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(12) United States Patent (10) Patent No.: US 9,011,834 B1 Mckenzie Et Al USOO901 1834B1 (12) United States Patent (10) Patent No.: US 9,011,834 B1 McKenzie et al. (45) Date of Patent: Apr. 21, 2015 (54) COMPOSITIONS AND METHODS 7,632,520 B2 * 12/2009 Khandelwal .................. 424/464 (71) Applicant: Seres Health, Inc., Cambridge, MA 7,731,9767,708,988 B2 6,5, 2010 CobbFarmer (US) 7,763,420 B2 7/2010 Stritzker et al. (72) Inventors: Gregory McKenzie, Arlington, MA 7.981,411 B2 7/2011 Nadeau et al. (US); Mary-Jane Lombardo 7.998.473 B2 8/2011 Boileau et al. Ncity Spid 8,034,6018,021,654 B2 10/20119/2011 RehbergerBoileau et al. Cook, Brooklyn, NY (US); Marin 8,039,006 B2 10/2011 Prato Vulic, Boston, MA (US); Geoffrey von 8, 147,482 B2 4/2012 Shimizu Maltzahn, Boston, MA (US); Brian 8, 187,590 B2 5, 2012 Farmer Goodman, Boston, MA (US); John 8,236,508 B2 8/2012 Mutharasan Grant Aunins, Doylestown, PA (US); E. R: 258 ity Matthew R. 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