DOCSLIB.ORG

Aerobic Gram-Positive Bacteria

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Aerobic Gram-Positive Bacteria Aerobic Gram-Positive Bacteria Abiotrophia defectiva Corynebacterium xerosisB Micrococcus lylaeB Staphylococcus warneri Aerococcus sanguinicolaB Dermabacter hominisB Pediococcus acidilactici Staphylococcus xylosusB Aerococcus urinaeB Dermacoccus nishinomiyaensisB Pediococcus pentosaceusB Streptococcus agalactiae Aerococcus viridans Enterococcus avium Rothia dentocariosaB Streptococcus anginosus Alloiococcus otitisB Enterococcus casseliflavus Rothia mucilaginosa Streptococcus canisB Arthrobacter cumminsiiB Enterococcus durans Rothia aeriaB Streptococcus equiB Brevibacterium caseiB Enterococcus faecalis Staphylococcus auricularisB Streptococcus constellatus Corynebacterium accolensB Enterococcus faecium Staphylococcus aureus Streptococcus dysgalactiaeB Corynebacterium afermentans groupB Enterococcus gallinarum Staphylococcus capitis Streptococcus dysgalactiae ssp dysgalactiaeV Corynebacterium amycolatumB Enterococcus hiraeB Staphylococcus capraeB Streptococcus dysgalactiae spp equisimilisV Corynebacterium aurimucosum groupB Enterococcus mundtiiB Staphylococcus carnosusB Streptococcus gallolyticus ssp gallolyticusV Corynebacterium bovisB Enterococcus raffinosusB Staphylococcus cohniiB Streptococcus gallolyticusB Corynebacterium coyleaeB Facklamia hominisB Staphylococcus cohnii ssp cohniiV Streptococcus gordoniiB Corynebacterium diphtheriaeB Gardnerella vaginalis Staphylococcus cohnii ssp urealyticusV Streptococcus infantarius ssp coli (Str.lutetiensis)V Corynebacterium freneyiB Gemella haemolysans Staphylococcus delphiniB Streptococcus infantarius ssp infantariusV B = FDA-approved/cleared for the MALDI Biotyper CA system only V = FDA-approved/cleared for the Vitek MS system only © MFMER | slide-16 Aerobic Gram-Positive Bacteria, Continued Corynebacterium glucuronolyticumB Gemella morbillorum Staphylococcus epidermidis Streptococcus intermediusB Corynebacterium glutamicumB Gemella sanguinisB Staphylococcus equorumB Streptococcus lutetiensisB Corynebacterium jeikeium Granulicatella adiacens Staphylococcus felisB Streptococcus mitis/Streptococcus oralisV Corynebacterium kroppenstedtiiB Helcococcus kunziiB Staphylococcus haemolyticus Streptococcus mitis/oralis groupB Corynebacterium macginleyiB Kocuria kristinaeB Staphylococcus hominis Streptococcus mutans Corynebacterium minutissimumB Kytococcus sedentariusB Staphylococcus intermediusB Streptococcus parasanguinisB Corynebacterium mucifaciens / ureicelerivorans Lactobacillus jenseniiB Staphylococcus lentusB Streptococcus pneumoniae groupB Corynebacterium propinquumB Lactobacillus rhamnosusB Staphylococcus lugdunensis Streptococcus pyogenes Corynebacterium pseudodiphtheriticumB Lactococcus garvieae Staphylococcus pasteuriB Streptococcus salivarius / vestibularis groupB Corynebacterium pseudotuberculosisB Lactobacillus gasseriB Staphylococcus pettenkoferiB Streptococcus salivarius ssp salivariusi Corynebacterium resistensB Lactococcus lactis Staphylococcus pseudintermediusB Streptococcus sanguinis Corynebacterium riegeliiB Leuconostoc citreumB Staphylococcus saccharolyticusB Streptococcus sobrinusB Corynebacterium striatum groupB Leuconostoc mesenteroides Staphylococcus saprophyticus Streptococcus thermophilusB Corynebacterium tuberculostearicumB Leuconostoc pseudomenteroides Staphylococcus schleiferi Trueperella bernardiaeB Corynebacterium ulceransB Listeria monocytogenes Staphylococcus sciuri Turicella otitidisB Corynebacterium urealyticumB Macrococcus caseolyticusB Staphylococcus simulans Vagococcus fluvialisB Micrococcus luteus Staphylococcus vitulinusB B = FDA-approved/cleared for the MALDI Biotyper CA system only V = FDA-approved/cleared for the Vitek MS system only B = FDA-approved/cleared for the MALDI Biotyper CA system only V = FDA-approved/cleared for the Vitek MS system only © MFMER | slide-17 Gram-Negative Bacteria, Enterobacteriaceae Citrobacter amalonaticusV Enterobacter cancerogenusV Leclercia adecarboxylota Serratia fonticola Citrobacter amalonaticus complexB Enterobacter cloacaeV Morganella morganii Serratia liquefaciens Citrobacter braakiiV Enterobacter cloacae complexB Pantoea agglomerans Serratia marcescens Citrobacter freundiiV Pluralibacter gergoviae Plesiomonas shigelloidesB Serratia odorifera Citrobacter freundii complexB Escherichia coli Proteus mirabilis Serratia plymuthicaB Citrobacter koseri Escherichia fergusoniiV Proteus penneriV Serratia rubidaeaB Citrobacter youngaeV Escherichia hermannii Proteus vulgarisV Yersinia enterocolitica Cronobacter sakazakiiV Escherichia vulnerisB Proteus vulgaris groupB Yersinia frederiksenii Cronobacter sakazakii groupB Ewingella americana Providencia rettgeri Yersinia intermedia Edwardsiella hoshinaeV Hafnia alvei Providencia stuartii Yersinia kristensenii Edwardsiella tarda Klebsiella oxytocaV Raoultella ornitholyticaV Yersinia pseudotuberculosis Enterobacter aerogenes Klebsiella oxytoca / Raoultella Raoultella planticolaV ornithinolyticaB Enterobacter amingenusB Klebsiella pneumoniae Salmonella groupV Enterobacter asburiaeV Klebsiella variicolaB Salmonella spB B = FDA-approved/cleared for the MALDI Biotyper CA system only V = FDA-approved/cleared for the Vitek MS system only B = FDA-approved/cleared for the MALDI Biotyper CA system only V = FDA-approved/cleared for the Vitek MS system only © MFMER | slide-18 Gram-Negative Bacteria, Non-Enterobacteriaceae Achromobacter denitrificansV Aeromonas sp.B Chryseobacterium indologenes Pseudomonas putidaV Achromobacter xylosoxidans Alcaligenes faecalisB Cupriavidus pauculus groupB Pseudomonas putida groupB Acinetobacter baumannii complexV Alcaligenes faecalis ssp faecalisV Delftia acidovorans groupB Pseudomonas stuzeri Acinetobacter baumannii/nosocomialis groupB Bordetella groupB Elizabethkingia meningosepticaV Ralstonia pickettii Acinetobacter calcoaceticusB Bordetella hinziiB Elizabethkingia meningoseptica groupB Rhizobium radiobacter Acinetobacter haemolyticus Bordetella parapertussisV Fluoribacter bozemaniiB Sphingobacterium multivorum Acinetobacter johnsoniiB Bordetella pertussisV Mannheimia haemolytica groupB Sphingobacterium spiritivorum Acinetobacter junii Brevundimonas dimunutaV Myroides odoratimimusB Sphingomonas paucimobilisV Acinetobacter lwoffii Brevundimonas dimunuta groupB Myroides odoratusB Sphingomonas paucimobilis groupB Acinetobacter pittiiB Burkholderia cepacia complexB Ochrobactrum anthropi Stenotrophomonas maltophilia Acinetobacter radioresistensB Burkholderia gladioliB Pasteurella multocida Sutterella wadsworthensisB Acinetobacter ursingiiB Burkholderia multivorans Pseudomonas aeruginosa Vibrio choleraeV Aeromonas hydrophila/caviaeV Capnocytophaga ochraceaB Pseudomonas fluorescensV Vibrio parahaemolyticus Aeromonas salmonicidaB Capnocytophaga sputigenaB Pseudomonas fluorescens groupB Vibrio vulnificus Aeromonas sobriaV Chryseobacterium gleumB Pseudomonas oryzihabitansB Weeksella virosaB B = FDA-approved/cleared for the MALDI Biotyper CA system only V = FDA-approved/cleared for the Vitek MS system only © MFMER | slide-19 Fastidious Gram-Negative Bacteria Aggregatibacter actinomycetemcomitans Haemophilus influenzae Moraxella catarrhalisB Neisseria gonorrhoeae Aggregatibacter aphrophilus Haemophilus parahaemolyticusV Moraxella (Neisseria) ovisV Neisseria lactamicaB Aggregatibacter segnis Haemophilus parahaemolyticus Moraxella nonliquefaciensB Neisseria meningitidis groupB Campylobacter coli Haemophilus parainfluenzae Moraxella osloensisB Neisseria mucosa/siccaV Campylobacter jejuni Kingella denitrificans Neisseria bacilliformisB Neisseria sicca groupB Campylobacter ureolyticusB Kingella kingae Neisseria cinerea Neisseria weaveriB Eikenella corrodens Legionella longbeachaeB Neisseria elongataB Oligella ureolytica Haemophilus haemolyticusB Legionella pneumophila Neisseria flavescens/subflava groupB Oligella urethralis B = FDA-approved/cleared for the MALDI Biotyper CA system only V = FDA-approved/cleared for the Vitek MS system only © MFMER | slide-20 Anaerobic Bacteria Actinomyces europaeusB Bacteroides fragilis Clostridium clostridioforme groupB Parabacteroides distasonisB Actinomyces funkeiB Bacteroides nordiiB Clostridium clostridioformeV Parabacteroides johnsonii / merdae groupB Actinomyces graevenitziiB Bacteroides ovatus/xylanisolvensV Clostridium difficile Parabacteroides goldsteiniiB Actinomyces hyovaginalisB Bacteroides ovatus groupB Clostridium innocuumB Parvimonas micra Actinomyces meyeri Bacteroides pyogenesB Clostridium paraputrificumB Peptoniphilus asaccharolyticusV Actinomyces neuii Bacteroides salyersiaeB Clostridium perfringens Peptoniphilus harei groupB Actinomyces odontolyticus Bacteroides stercoris groupB Clostridium ramosum Peptostreptococcus anaerobius V Actinomyces radingaeB Bacteroides thetaiotaomicron Clostridium septicumB Porphyromonas gingivalisB Actinomyces turicensisB Bacteroides thetaiotaomicron groupB Clostridium sordelliiB Porphyromonas someraeB Actinomyces urogenitalisB Bacteroides uniformis Clostridium sporogenes / Clostridium Prevotella bivia botulinum (group I)B Actinomyces orisB Bacteroides vulgatusV Clostridium tertiumB Prevotella buccae Actinotignum schaalii groupB Bacteroides vulgatus groupB Finegoldia magna Prevotella denticola Alloscardovia omnicolensB Bifidobacterium breveB Fusobacterium canifelinumB Prevotella intermedia Anaerococcus murdochiiB Clostridium beijerinckiiB Fusobacterium necrophorum Prevotella melaninogenica Anaerococcus vaginalisB Clostridium bifermentansB Fusobacterium nucleatum Propionibacterium acnes Bacteroides caccae Clostridium butyricumB Mobiluncus curtsii Veillonella parvula groupB B = FDA-approved/cleared
Load more

Recommended publications
  • Official Nh Dhhs Health Alert
    THIS IS AN OFFICIAL NH DHHS HEALTH ALERT Distributed by the NH Health Alert Network [email protected] May 18, 2018, 1300 EDT (1:00 PM EDT) NH-HAN 20180518 Tickborne Diseases in New Hampshire Key Points and Recommendations: 1. Blacklegged ticks transmit at least five different infections in New Hampshire (NH): Lyme disease, Anaplasma, Babesia, Powassan virus, and Borrelia miyamotoi. 2. NH has one of the highest rates of Lyme disease in the nation, and 50-60% of blacklegged ticks sampled from across NH have been found to be infected with Borrelia burgdorferi, the bacterium that causes Lyme disease. 3. NH has experienced a significant increase in human cases of anaplasmosis, with cases more than doubling from 2016 to 2017. The reason for the increase is unknown at this time. 4. The number of new cases of babesiosis also increased in 2017; because Babesia can be transmitted through blood transfusions in addition to tick bites, providers should ask patients with suspected babesiosis whether they have donated blood or received a blood transfusion. 5. Powassan is a newer tickborne disease which has been identified in three NH residents during past seasons in 2013, 2016 and 2017. While uncommon, Powassan can cause a debilitating neurological illness, so providers should maintain an index of suspicion for patients presenting with an unexplained meningoencephalitis. 6. Borrelia miyamotoi infection usually presents with a nonspecific febrile illness similar to other tickborne diseases like anaplasmosis, and has recently been identified in one NH resident. Tests for Lyme disease do not reliably detect Borrelia miyamotoi, so providers should consider specific testing for Borrelia miyamotoi (see Attachment 1) and other pathogens if testing for Lyme disease is negative but a tickborne disease is still suspected.
    [Show full text]
  • Accuprobe Mycobacterium Avium Complex Culture
    non-hybridized and hybridized probe. The labeled DNA:RNA hybrids are measured in a Hologic luminometer. A positive result is a luminometer reading equal to or greater than the cut-off. A value below this cut-off is AccuProbe® a negative result. REAGENTS Note: For information on any hazard and precautionary statements that MYCOBACTERIUM AVIUM may be associated with reagents, refer to the Safety Data Sheet Library at www.hologic.com/sds. COMPLEX CULTURE Reagents for the ACCUPROBE MYCOBACTERIUM AVIUM COMPLEX IDENTIFICATION TEST CULTURE IDENTIFICATION TEST are provided in three separate reagent kits: INTENDED USE The ACCUPROBE MYCOBACTERIUM AVIUM COMPLEX CULTURE ACCUPROBE MYCOBACTERIUM AVIUM COMPLEX PROBE KIT IDENTIFICATION TEST is a rapid DNA probe test which utilizes the Probe Reagent. (4 x 5 tubes) technique of nucleic acid hybridization for the identification of Mycobacterium avium complex Mycobacterium avium complex (M. avium complex) isolated from culture. Lysing Reagent. (1 x 20 tubes) Glass beads and buffer SUMMARY AND EXPLANATION OF THE TEST Infections caused by members of the M. avium complex are the most ACCUPROBE CULTURE IDENTIFICATION REAGENT KIT common mycobacterial infections associated with AIDS and other Reagent 1 (Lysis Reagent). 1 x 10 mL immunocompromised patients (7,15). The incidence of M. avium buffered solution containing 0.04% sodium azide complex as a clinically significant pathogen in cases of chronic pulmonary disease is also increasing (8,17). Recently, several Reagent 2 (Hybridization Buffer). 1 x 10 mL laboratories have reported that the frequency of isolating M. avium buffered solution complex is equivalent to or greater than the frequency of isolating M.
    [Show full text]
  • Artus Mycobac. Diff. LC PCR Kit Handbook 10/2015 2
    October 2015 artus® Mycobac. diff. LC PCR Kit Handbook 24 96 Version 1 Quantitative in vitro diagnostics For use with the LightCycler® 1.1/1.2/1.5 and LightCycler 2.0 instruments 4556063 (24 reactions) 4556065 (96 reactions) QIAGEN GmbH QIAGEN Strasse 1 40724 Hilden GERMANY R4 1046963EN Sample to Insight__ Contents Summary and Explanation ...................................................................................................4 Principle of the Procedure ....................................................................................................4 Materials Provided .............................................................................................................6 Kit contents ..............................................................................................................6 Materials Required but Not Provided ....................................................................................7 Warnings and Precautions ..................................................................................................8 Warnings ................................................................................................................8 Reagent Storage and Handling ............................................................................................8 Procedure ..........................................................................................................................9 Important points before starting ..................................................................................9
    [Show full text]
  • ID 2 | Issue No: 4.1 | Issue Date: 29.10.14 | Page: 1 of 24 © Crown Copyright 2014 Identification of Corynebacterium Species
    UK Standards for Microbiology Investigations Identification of Corynebacterium species Issued by the Standards Unit, Microbiology Services, PHE Bacteriology – Identification | ID 2 | Issue no: 4.1 | Issue date: 29.10.14 | Page: 1 of 24 © Crown copyright 2014 Identification of Corynebacterium species Acknowledgments UK Standards for Microbiology Investigations (SMIs) are developed under the auspices of Public Health England (PHE) working in partnership with the National Health Service (NHS), Public Health Wales and with the professional organisations whose logos are displayed below and listed on the website https://www.gov.uk/uk- standards-for-microbiology-investigations-smi-quality-and-consistency-in-clinical- laboratories. SMIs are developed, reviewed and revised by various working groups which are overseen by a steering committee (see https://www.gov.uk/government/groups/standards-for-microbiology-investigations- steering-committee). The contributions of many individuals in clinical, specialist and reference laboratories who have provided information and comments during the development of this document are acknowledged. We are grateful to the Medical Editors for editing the medical content. For further information please contact us at: Standards Unit Microbiology Services Public Health England 61 Colindale Avenue London NW9 5EQ E-mail: [email protected] Website: https://www.gov.uk/uk-standards-for-microbiology-investigations-smi-quality- and-consistency-in-clinical-laboratories UK Standards for Microbiology Investigations are produced in association with: Logos correct at time of publishing. Bacteriology – Identification | ID 2 | Issue no: 4.1 | Issue date: 29.10.14 | Page: 2 of 24 UK Standards for Microbiology Investigations | Issued by the Standards Unit, Public Health England Identification of Corynebacterium species Contents ACKNOWLEDGMENTS .........................................................................................................
    [Show full text]
  • Naeglaria and Brain Infections
    Can bacteria shrink tumors? Cancer Therapy: The Microbial Approach n this age of advanced injected live Streptococcus medical science and into cancer patients but after I technology, we still the recipients unfortunately continue to hunt for died from subsequent innovative cancer therapies infections, Coley decided to that prove effective and safe. use heat killed bacteria. He Treatments that successfully made a mixture of two heat- eradicate tumors while at the killed bacterial species, By Alan Barajas same time cause as little Streptococcus pyogenes and damage as possible to normal Serratia marcescens. This Alani Barajas is a Research and tissue are the ultimate goal, concoction was termed Development Technician at Hardy but are also not easy to find. “Coley’s toxins.” Bacteria Diagnostics. She earned her bachelor's degree in Microbiology at were either injected into Cal Poly, San Luis Obispo. The use of microorganisms in tumors or into the cancer therapy is not a new bloodstream. During her studies at Cal Poly, much idea but it is currently a of her time was spent as part of the undergraduate research team for the buzzing topic in cancer Cal Poly Dairy Products Technology therapy research. Center studying spore-forming bacteria in dairy products. In the late 1800s, German Currently she is working on new physicians W. Busch and F. chromogenic media formulations for Fehleisen both individually Hardy Diagnostics, both in the observed that certain cancers prepared and powdered forms. began to regress when patients acquired accidental erysipelas (cellulitis) caused by Streptococcus pyogenes. William Coley was the first to use New York surgeon William bacterial injections to treat cancer www.HardyDiagnostics.com patients.
    [Show full text]
  • Diagnostic Code Descriptions (ICD9)
    INFECTIONS AND PARASITIC DISEASES INTESTINAL AND INFECTIOUS DISEASES (001 – 009.3) 001 CHOLERA 001.0 DUE TO VIBRIO CHOLERAE 001.1 DUE TO VIBRIO CHOLERAE EL TOR 001.9 UNSPECIFIED 002 TYPHOID AND PARATYPHOID FEVERS 002.0 TYPHOID FEVER 002.1 PARATYPHOID FEVER 'A' 002.2 PARATYPHOID FEVER 'B' 002.3 PARATYPHOID FEVER 'C' 002.9 PARATYPHOID FEVER, UNSPECIFIED 003 OTHER SALMONELLA INFECTIONS 003.0 SALMONELLA GASTROENTERITIS 003.1 SALMONELLA SEPTICAEMIA 003.2 LOCALIZED SALMONELLA INFECTIONS 003.8 OTHER 003.9 UNSPECIFIED 004 SHIGELLOSIS 004.0 SHIGELLA DYSENTERIAE 004.1 SHIGELLA FLEXNERI 004.2 SHIGELLA BOYDII 004.3 SHIGELLA SONNEI 004.8 OTHER 004.9 UNSPECIFIED 005 OTHER FOOD POISONING (BACTERIAL) 005.0 STAPHYLOCOCCAL FOOD POISONING 005.1 BOTULISM 005.2 FOOD POISONING DUE TO CLOSTRIDIUM PERFRINGENS (CL.WELCHII) 005.3 FOOD POISONING DUE TO OTHER CLOSTRIDIA 005.4 FOOD POISONING DUE TO VIBRIO PARAHAEMOLYTICUS 005.8 OTHER BACTERIAL FOOD POISONING 005.9 FOOD POISONING, UNSPECIFIED 006 AMOEBIASIS 006.0 ACUTE AMOEBIC DYSENTERY WITHOUT MENTION OF ABSCESS 006.1 CHRONIC INTESTINAL AMOEBIASIS WITHOUT MENTION OF ABSCESS 006.2 AMOEBIC NONDYSENTERIC COLITIS 006.3 AMOEBIC LIVER ABSCESS 006.4 AMOEBIC LUNG ABSCESS 006.5 AMOEBIC BRAIN ABSCESS 006.6 AMOEBIC SKIN ULCERATION 006.8 AMOEBIC INFECTION OF OTHER SITES 006.9 AMOEBIASIS, UNSPECIFIED 007 OTHER PROTOZOAL INTESTINAL DISEASES 007.0 BALANTIDIASIS 007.1 GIARDIASIS 007.2 COCCIDIOSIS 007.3 INTESTINAL TRICHOMONIASIS 007.8 OTHER PROTOZOAL INTESTINAL DISEASES 007.9 UNSPECIFIED 008 INTESTINAL INFECTIONS DUE TO OTHER ORGANISMS
    [Show full text]
  • Upper and Lower Case Letters to Be Used
    Isolation, characterization and genome sequencing of a soil-borne Citrobacter freundii strain capable of detoxifying trichothecene mycotoxins by Rafiqul Islam A Thesis Presented to The University of Guelph In Partial Fulfilment of Requirements for the Degree of Doctor of Philosophy in Plant Agriculture Guelph, Ontario, Canada © Rafiqul Islam, April, 2012 ABSTRACT ISOLATION, CHARACTERIZATION AND GENOME SEQUENCING OF A SOIL- BORNE CITROBACTER FREUNDII STRAIN CAPABLE OF DETOXIFIYING TRICHOTHECENE MYCOTOXINS Rafiqul Islam Advisors: University of Guelph, 2012 Dr. K. Peter Pauls Dr. Ting Zhou Cereals are frequently contaminated with tricthothecene mycotoxins, like deoxynivalenol (DON, vomitoxin), which are toxic to humans, animals and plants. The goals of the research were to discover and characterize microbes capable of detoxifying DON under aerobic conditions and moderate temperatures. To identify microbes capable of detoxifying DON, five soil samples collected from Southern Ontario crop fields were tested for the ability to convert DON to a de-epoxidized derivative. One soil sample showed DON de-epoxidation activity under aerobic conditions at 22-24°C. To isolate the microbes responsible for DON detoxification (de-epoxidation) activity, the mixed culture was grown with antibiotics at 50ºC for 1.5 h and high concentrations of DON. The treatments resulted in the isolation of a pure DON de-epoxidating bacterial strain, ADS47, and phenotypic and molecular analyses identified the bacterium as Citrobacter freundii. The bacterium was also able to de-epoxidize and/or de-acetylate 10 other food-contaminating trichothecene mycotoxins. A fosmid genomic DNA library of strain ADS47 was prepared in E. coli and screened for DON detoxification activity. However, no library clone was found with DON detoxification activity.
    [Show full text]
  • Metatranscriptomic Analysis Reveals Active Bacterial Communities in Diabetic Foot Infections
    fmicb-11-01688 July 20, 2020 Time: 12:22 # 1 ORIGINAL RESEARCH published: 22 July 2020 doi: 10.3389/fmicb.2020.01688 Metatranscriptomic Analysis Reveals Active Bacterial Communities in Diabetic Foot Infections Fatemah Sadeghpour Heravi1, Martha Zakrzewski2, Karen Vickery1, Matthew Malone3,4,5 and Honghua Hu1* 1 Surgical Infection Research Group, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia, 2 QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia, 3 Infectious Diseases and Microbiology, School of Medicine, Western Sydney University, Sydney, NSW, Australia, 4 Liverpool Hospital, South Western Sydney LHD, Sydney, NSW, Australia, 5 Liverpool Diabetes Collaborative Research Unit, Ingham Institute for Applied Medical Research, Sydney, NSW, Australia Despite the extended view of the composition of diabetic foot infections (DFIs), little is known about which transcriptionally active bacterial communities are pertinent to infection, and if any differences are associated with increased infection severity. We applied a RNA sequencing approach to analyze the composition, function, and pathogenicity of the active bacterial communities in DFIs. Taxonomic profiling of bacterial transcripts revealed the presence of 14 bacterial phyla in DFIs. The abundance Edited by: Qi Zhao, of the Spiroplasma, Vibrio, and Mycoplasma were significantly different in different Liaoning University, China infection severities (P < 0.05). Mild and severe stages of infections were dominated Reviewed by: by Staphylococcus aureus and Porphyromonas asaccharolytica, respectively. A total of Patrick R. M. Harnarayan, The University of the West Indies 132 metabolic pathways were identified of which ribosome and thiamin being among the at St. Augustine, Trinidad and Tobago most highly transcribed pathways. Moreover, a total of 131 antibiotic resistance genes, Maria José Saavedra, primarily involved in the multidrug efflux pumps/exporters, were identified.
    [Show full text]
  • Corynebacterium Species Rarely Cause Orthopedic Infections
    Zurich Open Repository and Archive University of Zurich Main Library Strickhofstrasse 39 CH-8057 Zurich www.zora.uzh.ch Year: 2018 Corynebacterium species rarely cause orthopedic infections Kalt, Fabian ; Schulthess, Bettina ; Sidler, Fabian ; Herren, Sebastian ; Fucentese, Sandro F ; Zingg, Patrick O ; Berli, Martin ; Zinkernagel, Annelies S ; Zbinden, Reinhard ; Achermann, Yvonne Abstract: Corynebacterium spp. are rarely considered as pathogens but data in orthopedic infections are sparse. Therefore, we asked how often Corynebacterium spp. caused an infection in a defined cohort of orthopedic patients with a positive culture. In addition, we aimed to determine the species variety and susceptibility of isolated strains in regards to potential treatment strategies. Between 2006 and 2015, we retrospectively assessed all Corynebacterium sp. bone and joint cultures from an orthopedic ward. The isolates were considered as relevant indicating an infection if the same Corynebacterium sp. was present in at least two samples. We found 97 orthopedic cases with isolation of Corynebacterium spp. (128 positive samples), mainly Corynebacterium tuberculostearicum (n=26), Corynebacterium amycolatum (n=17), Corynebacterium striatum (n=13), and Corynebacterium afermentans (n=11). Compared to a cohort of positive blood cultures, we found significantly more C. striatum and C. tuberculostearicum but no C. jeikeium cases. Only 16 cases out 66 cases (24.2%) with an available diagnostic set of at least 2 samples had an infection. Antibiotic susceptibility testing (AST) of different antibiotics showed various susceptibility results except for vancomycin and linezolid with a 100% susceptibility rate. Rates of susceptibility of corynebacteria isolated from orthopedic samples and of isolates from blood cultures were comparable. In conclusion, our study results confirmed that Corynebacterium sp.
    [Show full text]
  • Actinomycesspp & Nocardiaspp
    PLUMB’S THERAPEUTICS BRIEF h PATHOGEN PROFILE h PEER REVIEWED Actinomyces spp & Nocardia spp J. Scott Weese, DVM, DVSc, DACVIM University of Guelph Actinomyces spp and Nocardia spp are members of class Acti- Nocardia spp nobacteria, which can cause opportunistic infections in dogs, The Nocardia genus contains more than 30 saprophytic species cats, and other species. Both can cause pyogranulomatous or that are widely, if not ubiquitously, disseminated in the environ- suppurative disease that is often slowly progressing and chal- ment. Disease occurs following inoculation of the bacterium into lenging to diagnose; however, some differences in organism tissue or via inhalation. and characteristics exist (Table 1, next page). The incidence of h Nocardia spp are regionally variable, with higher rates of disease caused by either is undefined and likely low. infection in dry, dusty, and windy regions (eg, southwestern United States, parts of Australia). Actinomyces spp h Nocardiosis is classically divided into 3 clinical forms: Many different species are present, and taxonomy continues to pulmonary, disseminated (systemic), and cutaneous/ change; some species previously known as Actinomyces have subcutaneous.11-15 been reclassified in other genera, such as Arcanobacterium spp • Clinical presentations are as would be expected with pul- and Trueperella spp. Regardless, disease aspects remain monary, systemic, or cutaneous infections. Pulmonary or unchanged. Commonly found as part of the oral, GI, and genital cutaneous disease can progress to disseminated disease. microbiotas,1-3 Actinomyces spp and related genera are of lim- ited virulence unless inoculated into tissue (eg, via bites, foreign Diagnosis bodies, or trauma). Early diagnosis may be missed.
    [Show full text]
  • Intraspecies Comparative Genomics of Rickettsia
    AIX ͲMARSEILLE UNIVERSITÉ FACULTÉ DE MÉDECINE DE MARSEILLE ÉCOLE DOCTORALE DES SCIENCES DE LA VIE ET DE LA SANTÉ T H È S E Présentée et publiquement soutenue devant LA FACULTÉ DE MÉDECINE DE MARSEILLE Le 13 décembre 2013 Par M. Erwin SENTAUSA Né le 16 décembre 1979 àMalang, Indonésie INTRASPECIES COMPARATIVE GENOMICS OF RICKETTSIA Pour obtenir le grade de DOCTORAT d’AIX ͲMARSEILLE UNIVERSITÉ SPÉCIALITÉ :PATHOLOGIE HUMAINE Ͳ MALADIES INFECTIEUSES Membres du Jury de la Thèse : Dr. Patricia RENESTO Rapporteur Pr. Max MAURIN Rapporteur Dr. Florence FENOLLAR Membre du Jury Pr. Pierre ͲEdouard FOURNIER Directeur de thèse Unité de Recherche sur les Maladies Infectieuses et Tropicales Émergentes UM63, CNRS 7278, IRD 198, Inserm 1095 Avant Propos Le format de présentation de cette thèse correspond à une recommandation de la spécialité Maladies Infectieuses et Microbiologie, à l’intérieur du Master de Sciences de la Vie et de la Santé qui dépend de l’Ecole Doctorale des Sciences de la Vie de Marseille. Le candidat est amené àrespecter des règles qui lui sont imposées et qui comportent un format de thèse utilisé dans le Nord de l’Europe permettant un meilleur rangement que les thèses traditionnelles. Par ailleurs, la partie introduction et bibliographie est remplacée par une revue envoyée dans un journal afin de permettre une évaluation extérieure de la qualité de la revue et de permettre àl’étudiant de le commencer le plus tôt possible une bibliographie exhaustive sur le domaine de cette thèse. Par ailleurs, la thèse est présentée sur article publié, accepté ou soumis associé d’un bref commentaire donnant le sens général du travail.
    [Show full text]
  • Twenty Years of Passive Disease Surveillance of Roe Deer (Capreolus Capreolus) in Slovenia
    animals Article Twenty Years of Passive Disease Surveillance of Roe Deer (Capreolus capreolus) in Slovenia Diana Žele Vengušt 1, Urška Kuhar 2, Klemen Jerina 3 and Gorazd Vengušt 1,* 1 Institute of Pathology, Wild Animals, Fish and Bees, Veterinary Faculty, University of Ljubljana, Gerbiˇceva60, 1000 Ljubljana, Slovenia; [email protected] 2 Institute of Microbiology and Parasitology, Veterinary Faculty, University of Ljubljana, Gerbiˇceva60, 1000 Ljubljana, Slovenia; [email protected] 3 Department of Forestry and Renewable Forest Resources, Biotechnical Faculty, Veˇcnapot 83, 1000 Ljubljana, Slovenia; [email protected] * Correspondence: [email protected]; Tel.: +386-(1)-4779-196 Simple Summary: Wildlife can serve as a reservoir for highly contagious and deadly diseases, many of which are infectious to domestic animals and/or humans. Wildlife disease surveillance can be considered an essential tool to provide important information on the health status of the population and for the protection of human health. Between 2000 and 2019, examinations of 510 roe deer carcasses were conducted by comprehensive necropsy and other laboratory tests. In conclusion, the results of this research indicate a broad spectrum of roe deer diseases, but no identified disease can be considered a significant health threat to other wildlife species and/or to humans. Abstract: In this paper, we provide an overview of the causes of death of roe deer (Capreolus capreolus) diagnosed within the national passive health surveillance of roe deer in Slovenia. From 2000 to 2019, postmortem examinations of 510 free-ranging roe deer provided by hunters were conducted at the Veterinary Faculty, Slovenia.
    [Show full text]