Case Report Peripheral Ossifying Fibroma Associated with a Neonatal

Total Page:16

File Type:pdf, Size:1020Kb

Load more

Case Report Peripheral ossifying fibroma associated with a neonatal tooth: case report K. Kohli, DDS A. Christian,DDS R. Howell, DDS, MSD, BS eripheral ossifying fibroma (POP) is a relatively only approximately half of the crown formed. The child common reactive gingival growth of uncertain was seen for a 1-week post-op check-up during which Ppathogenesis.' In the literature, this pathologic time it was noted that the extraction site was covered lesion sometimes has been described as an ossifying fi- by a mass that was 8x4x4 mm. A pathology consul- broid epulis, a peripheral fibroma with calcification or tation was requested and the lesion was clinically a calcifying granuloma.2 In 1982, Gardner recom- diagnosed as a pyogenic granuloma. Reevaluation was mended that the only term used to describe this entity recommended and if there was no reduction in size, should be POP.3 the lesion was to be surgically excised. The mass was POP are seen usually in teenagers and young adults, excised in the dental clinic at 4 weeks of age using lo- with an occurrance peak between the ages of 10 and cal anesthesia. Histologic examination of the excised 19 years.4 A literature review revealed the youngest re- mass revealed a ._____________________, ported age of a POP was in a 7-month-old infant. The lesion consisting purpose of this report is to present a case in a neonate. primarily of granulation tis- Cose report sue with an A consultation was requested by the Nursery at Ruby ulcerated sur- Memorial Hospital of West Virginia University on a face. Also noted 2-hour-old, Caucasian female neonate, birth weight of was an eosino- 7 lbs, 5oz, gestational age of 37 weeks, who was deliv- philic material ered vaginally with no complications. The otherwise in the connective healthy neonate was said to have a small cyst-like mass tissue exhibiting Fig 2. Histology of granulation tissue with an in the anterior mandibular ridge area, approximately osteiod appear- ulcerated surface. 20 x 12x6 mm. Clinical examination revealed a soft, ance (Fig 2) a fluid-filled, pink fluctuant mass. The clinical differen- final diagnosis of a POP was rendered. The child was tial diagnosis was that of a gingival cyst of newborn or followed for 2 weeks after the excision, during which an eruption cyst (Fig 1). The infant was seen at the time the alveolar mucosa healed uneventfully. dental clinic a week later with a neonatal tooth erupt- ing through the site of the cyst. Radiographic Discussion examination The clinical features of a POP were described by was not at- Buchner and Hansen, and consisted of a localized tempted as the growth on the gingiva with a pedunculated or sessile parents did not base.' POFs usually range in color from pink to red and want the baby commonly occur on the interdental papilla. It is im- to be exposed possible to identify the cause of growth in most cases, to any radia- but a multitude of possible irritants have been identi- tion. Clinical fied including calculus, plaque, microorganisms, dental examination appliances, and ill-fitting crowns.5'6 The POP is a re- revealed that active lesion of soft tissue in contact with osseous Fig 1. Gingival cyst in newborn. the neonatal structures and is only seen in soft tissues over bone. tooth had third POFs differ from a clinically similar lesion, the periph- degree mobility and was causing a lot of discomfort to eral odontogenic fibroma, in that they lack the the mother during nursing. It was decided to extract odontogenic components found in this latter lesion. the tooth at 1 week of age. The extracted tooth had While ossification may occur in soft tissues associated 428 American Academy of Pediatric Dentistry Pediatric Dentistry - 20:7, 1998 with bone, they are generally consideredto be either a The recommendedtreatment of POFis a local sur- choristomas, such as an osteomaof the tongue, or an gical excision that extends to include the periosteum osseous metaplasia, such as bone or cartilage seen in with9 submission for histomorphologic examination. somesalivary gland tumors. While POFoccurrence is Inclusion of the periosteum during the excision de- uncommonin the neonate, it is’ not difficult to ratio- creases the recurrence of this lesion.1 Kenneyet al. nalize that the active growthof the alveolar bonein the reported a 14%recurrence rate of POF. Whentaking neonate jaw, whenstimulated by removal of the neo- into accountthe reactive nature of this lesion, this rate natal tooth, might respondwith an exuberantperiosteal mayreflect incompleteinitial removalor repeated in- response and form a reactive lesion with somepoten- jury. 4 Buchner and Hansen reported a recurrence of tial for bone production. Thelesions usually range in 16%, Levin and North reported a recurrence of 10- size from 0.1 to 1.0 cm.5 POFduration has been re- 20%, and Bhaskar and Jacowayreported recurrence of ported by Buchner and Hansen as two weeks to 20 8%. 1, 7, 10 years, with a mean of 11.5 months.1 Bhaskar and In summary,POF is an entity that can be seen in Jacowayreported that the average duration of the le- neonates. Therefore, it maybe necessary to include sion7 was 18.6 months. POFin the differential diagnosis of anterior alveolar According to Bodner and Dayan, POFs can occur masses in the neonate. The presence of POFcan be at any age, but rarely occur before age 10 and are most very overwhelmingto a new mother and it becomes commonin the second decade of life. < 5 Buchnerand imperative to educate newparents of the recurrence Hansenreported an age range of 7 to 90 years with a rate associated with POF.It also is advisable to biopsy meanof 30 years. 1 Kenneyreports incidence between the mass whenexcised to help arrive at the appropri- 54 and 25 years with incidence decreasing each decade. ate diagnosis. Bhaskar and Jacowayreported a 64%predilection for Dr. Kohli is an assistant professor and Interim Director in the occurrence of the lesion in females, which was very 1’7 Division of Pediatric Dentistry, Dr. Howellis professor and Chair similar to the 63%reported by Buchnerand Hansen. of Departmentof Oral and Maxillofacial Pathology. At the time According to Buchner and Hansen, POFs occurred this paper was written, AshleyChristian was a fourth-year dental 60%of the time in the maxilla and 40%in the man- student at WVU-Schoolof Dentistry, West Virginia. dible, and 54%occurred in the incisor/cuspid region, l Kenneyet al. reported that occurrencewas equal in the References maxilla and the mandible, with 80%of the lesions 4 1. Buchner A, Hansen LS: The histomorphological spectrum developingin the anterior region. of peripheral ossifying fibroma. Oral Surg Oral MedOral Histologically, POFsare a nonencapsulatedmass of Pathol 63:452-61, 1987. a cellular flbroblastic connectivetissue coveredby strati- 2. Zain RB,Fei YJ: Fibrous lesions of the gingiva: a histopatho- fied squamous epithelium. There exists a wide logic analysis of 204 cases. Oral Surg Oral MedOral Pathol histomorphologicspectrum for this entity, which can 70:466-70, 1990. makeit difficult to distinguish this fromother lesions. 3. Gardner DG: The peripheral odontogenic fibroma: an at- tempt at clarification. Oral Surg Oral MedOral Pathol In its early stages, the lesion maybe ulcerated and com- 54:40-48, 1982. posedof cellular, fibroblastic tissue with granular foci 4. KenneyJN, Kaugars GE, Abbey LM: Comparison between of dystrophic mineralization. Buchner and Hansen the peripheral ossifying fibroma and peripheral odontoge- state that at this early stage somelesions havebeen clini- nic flbroma. J Oral Maxillofac Surg 47:378-82, 1989. cally diagnosed as a pyogenicgranuloma. 1 This lesion 5. Bodner L, DayanD: Growthpotential of peripheral ossify- often appears ulcerated at first and is characterized by ing fibroma. J Clin Periodontol 14:551-54, 1987. 6. Poon CK, KwanPC, Chao SY: Giant peripheral ossifying a highly cellular fibroblastic connectivetissue with ar- fibroma of the maxilla: report of a case. J Oral Maxillofac eas of dystrophiccalcification and osteogenesis. Asthe Surg 53:695-98, 1995. ulcer heals, the dystrophic calcification matures into 7. Bhaskar SN, JacowayJR:Peripheral fibroma and peripheral bone and the cellular flbroblastic connective tissue fibroma with calcification: report of 376 cases. J AmDent maturesto give the appearanceof a fibrous epulis.l Assoc 73:1312-20, 1966. According to Michaelides, peripheral odontogenic 8. Michaelides PL: Recurrent peripheral odontogenic fibroma fibroma must be hisologically differentiated from of the attached gingiva: a case report. J Periodontol 63:645- POF.8 Themain histological difference is the presence 47, 1992. 9. Neville BW, DammDD, Allen CM, Bouquot JE: Oral and of odontogenic epithelium in peripheral odontogenic Maxillofacial Pathology, 1st Ed.,Philadelphia: WBSaunders, fibroma. pp 374-76, 1995. 10. Levin LS, North AF: Peripheral ossifying fibroma. A case report. J MdState Dent Assoc 28:89-90, 1985. PediatricDentistry -20.’Z 1998 AmericanAcademy of Pediatric Dentistry429 .
Recommended publications
  • Clinical Features of Benign Tumors of the External Auditory Canal According to Pathology

    Clinical Features of Benign Tumors of the External Auditory Canal According to Pathology

    Central Annals of Otolaryngology and Rhinology Research Article *Corresponding author Jae-Jun Song, Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Clinical Features of Benign Medicine, 148 Gurodong-ro, Guro-gu, Seoul, 152-703, South Korea, Tel: 82-2-2626-3191; Fax: 82-2-868-0475; Tumors of the External Auditory Email: Submitted: 31 March 2017 Accepted: 20 April 2017 Canal According to Pathology Published: 21 April 2017 ISSN: 2379-948X Jeong-Rok Kim, HwibinIm, Sung Won Chae, and Jae-Jun Song* Copyright Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College © 2017 Song et al. of Medicine, South Korea OPEN ACCESS Abstract Keywords Background and Objectives: Benign tumors of the external auditory canal (EAC) • External auditory canal are rare among head and neck tumors. The aim of this study was to analyze the clinical • Benign tumor features of patients who underwent surgery for an EAC mass confirmed as a benign • Surgical excision lesion. • Recurrence • Infection Methods: This retrospective study involved 53 patients with external auditory tumors who received surgical treatment at Korea University, Guro Hospital. Medical records and evaluations over a 10-year period were examined for clinical characteristics and pathologic diagnoses. Results: The most common pathologic diagnoses were nevus (40%), osteoma (13%), and cholesteatoma (13%). Among the five pathologic subgroups based on the origin organ of the tumor, the most prevalent pathologic subgroup was the skin lesion (47%), followed by the epithelial lesion (26%), and the bony lesion (13%). No significant differences were found in recurrence rate, recurrence duration, sex, or affected side between pathologic diagnoses.
  • Bone and Soft Tissue Tumors Have Been Treated Separately

    Bone and Soft Tissue Tumors Have Been Treated Separately

    EPIDEMIOLOGY z Sarcomas are rare tumors compared to other BONE AND SOFT malignancies: 8,700 new sarcomas in 2001, with TISSUE TUMORS 4,400 deaths. z The incidence of sarcomas is around 3-4/100,000. z Slight male predominance (with some subtypes more common in women). z Majority of soft tissue tumors affect older adults, but important sub-groups occur predominantly or exclusively in children. z Incidence of benign soft tissue tumors not known, but Fabrizio Remotti MD probably outnumber malignant tumors 100:1. BONE AND SOFT TISSUE SOFT TISSUE TUMORS TUMORS z Traditionally bone and soft tissue tumors have been treated separately. z This separation will be maintained in the following presentation. z Soft tissue sarcomas will be treated first and the sarcomas of bone will follow. Nowhere in the picture….. DEFINITION Histological z Soft tissue pathology deals with tumors of the classification connective tissues. of soft tissue z The concept of soft tissue is understood broadly to tumors include non-osseous tumors of extremities, trunk wall, retroperitoneum and mediastinum, and head & neck. z Excluded (with a few exceptions) are organ specific tumors. 1 Histological ETIOLOGY classification of soft tissue tumors tumors z Oncogenic viruses introduce new genomic material in the cell, which encode for oncogenic proteins that disrupt the regulation of cellular proliferation. z Two DNA viruses have been linked to soft tissue sarcomas: – Human herpes virus 8 (HHV8) linked to Kaposi’s sarcoma – Epstein-Barr virus (EBV) linked to subtypes of leiomyosarcoma z In both instances the connection between viral infection and sarcoma is more common in immunosuppressed hosts.
  • CASE REPORT Intradermal Nevus of the External Auditory Canal

    CASE REPORT Intradermal Nevus of the External Auditory Canal

    Int. Adv. Otol. 2009; 5:(3) 401-403 CASE REPORT Intradermal Nevus of the External Auditory Canal: A Case Report Sedat Ozturkcan, Ali Ekber, Riza Dundar, Filiz Gulustan, Demet Etit, Huseyin Katilmis Department of Otorhinolaryngology and Head and Neck Surgery ‹zmir Atatürk Research and Training Hospital, Ministry of Health, ‹ZM‹R-TURKEY (SO, AE, FG, DE, HK) Department of Otorhinolaryngology and Head and Neck Surgery Etimesgut Military Hospital , ANKARA-TURKEY (RD) Intradermal nevus is the most common skin tumor in humans; however, its occurrence in the external auditory canal (EAC) is uncommon. The clinical manifestations of pigmented nevus of the EAC have been reported to include ear fullness, foreign body sensation, hearing impairment, and otalgia, but some cases were asymptomatic and were found incidentally. The treatment of choice for a symptomatic intradermal nevus in the EAC is complete excision. There has been no recurrence reported in the literature . A pedunculated, papillomatous hair-bearing lesion was detected in the external auditory canal of the patient who was on follow-up for pruritus. Clinical and pathologic features of an intradermal nevus of the external auditory canal are presented, and the literature reviewed. Submitted : 14 October 2008 Revised : 01 July 2009 Accepted : 09 July 2009 Intradermal nevus is the most common skin tumor in left external auditory canal. Otomicroscopic humans; however, its occurrence in the external examination revealed a pedunculated, papillomatous auditory canal (EAC) is uncommon [1-4]. Intradermal hair-bearing lesion in the postero-inferior cartilaginous nevus is considered to be a form of benign cutaneous portion of the external auditory canal (Figure 1).
  • A Case of Intradermal Melanocytic Nevus with Ossification (Nevus of Nanta)

    A Case of Intradermal Melanocytic Nevus with Ossification (Nevus of Nanta)

    197 A Case of Intradermal Melanocytic Nevus with Ossification (Nevus of Nanta) Young Bok Lee, M.D., Kyung Ho Lee, M.D., Chul Jong Park, M.D. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea A 49-year-old woman presented with a 30-year history of asymptomatic plaque on her right temple. The histological examination revealed nests of nevus cells throughout the entire dermis. Bony spicules were seen just beneath the nevus cell nests in the lower dermis. Cutaneous ossification is an unusual event. Herein, we present a case of intradermal melanocytic nevus with unusual ossification (nevus of Nanta). To the best of our knowledge, this is the first such case report in the Korean literature. (Ann Dermatol (Seoul) 20(4) 197∼199, 2008) Key Words: Melanocytic nevus, Ossification INTRODUCTION drug intake or medical illness. The histological examination showed a dense proliferation of benign Ossification within the skin may occur in a nevus cells in the upper dermis. They were arranged variety of conditions, including pilomatricoma, basal in nests surrounding the hair follicles (Fig. 2). Bony cell carcinoma, appendageal and fibrous prolifera- spicules were seen in the lower dermis, underneath 1,2 tion, inflammation and trauma . The occurrence of the nevus cell nests. Some of them were compact ossification within a melanocytic nevus is an un- while others were surrounded by mature fatty tissue 3-5 usual event . (Fig. 3). Herein, we present a case of intradermal melano- cytic nevus with unusual ossification (nevus of Nanta). To the best our knowledge, this is the first such case report in the Korean literature.
  • Basal Cell Carcinoma Associated with Non-Neoplastic Cutaneous Conditions: a Comprehensive Review

    Basal Cell Carcinoma Associated with Non-Neoplastic Cutaneous Conditions: a Comprehensive Review

    Volume 27 Number 2| February 2021 Dermatology Online Journal || Review 27(2):1 Basal cell carcinoma associated with non-neoplastic cutaneous conditions: a comprehensive review Philip R Cohen MD1,2 Affiliations: 1San Diego Family Dermatology, National City, California, USA, 2Touro University California College of Osteopathic Medicine, Vallejo, California, USA Corresponding Author: Philip R Cohen, 10991 Twinleaf Court, San Diego, CA 92131-3643, Email: [email protected] pathogenesis of BCC is associated with the Abstract hedgehog signaling pathway and mutations in the Basal cell carcinoma (BCC) can be a component of a patched homologue 1 (PCTH-1) transmembrane collision tumor in which the skin cancer is present at tumor-suppressing protein [2-4]. Several potential the same cutaneous site as either a benign tumor or risk factors influence the development of BCC a malignant neoplasm. However, BCC can also concurrently occur at the same skin location as a non- including exposure to ultraviolet radiation, genetic neoplastic cutaneous condition. These include predisposition, genodermatoses, immunosuppression, autoimmune diseases (vitiligo), cutaneous disorders and trauma [5]. (Darier disease), dermal conditions (granuloma Basal cell carcinoma usually presents as an isolated faciale), dermal depositions (amyloid, calcinosis cutis, cutaneous focal mucinosis, osteoma cutis, and tumor on sun-exposed skin [6-9]. However, they can tattoo), dermatitis, miscellaneous conditions occur as collision tumors—referred to as BCC- (rhinophyma, sarcoidal reaction, and varicose veins), associated multiple skin neoplasms at one site scars, surgical sites, systemic diseases (sarcoidosis), (MUSK IN A NEST)—in which either a benign and/or systemic infections (leischmaniasis, leprosy and malignant neoplasm is associated with the BCC at lupus vulgaris), and ulcers.
  • Osteoid Osteoma and Your Everyday Practice

    Osteoid Osteoma and Your Everyday Practice

    n Review Article Instructions 1. Review the stated learning objectives at the beginning cme ARTICLE of the CME article and determine if these objectives match your individual learning needs. 2. Read the article carefully. Do not neglect the tables and other illustrative materials, as they have been selected to enhance your knowledge and understanding. 3. The following quiz questions have been designed to provide a useful link between the CME article in the issue Osteoid Osteoma and your everyday practice. Read each question, choose the correct answer, and record your answer on the CME Registration Form at the end of the quiz. Petros J. Boscainos, MD, FRCSEd; Gerard R. Cousins, MBChB, BSc(MedSci), MRCS; 4. Type or print your full name and address and your date of birth in the space provided on the CME Registration Form. Rajiv Kulshreshtha, MBBS, MRCS; T. Barry Oliver, MBChB, MRCP, FRCR; 5. Indicate the total time spent on the activity (reading article and completing quiz). Forms and quizzes cannot be Panayiotis J. Papagelopoulos, MD, DSc processed if this section is incomplete. All participants are required by the accreditation agency to attest to the time spent completing the activity. educational objectives 6. Complete the Evaluation portion of the CME Regi stration Form. Forms and quizzes cannot be processed if the Evaluation As a result of reading this article, physicians should be able to: portion is incomplete. The Evaluation portion of the CME Registration Form will be separated from the quiz upon receipt at ORTHOPEDICS. Your evaluation of this activity will in no way affect educational1.
  • Basal Cell Carcinoma with Osteoma Cutis

    Basal Cell Carcinoma with Osteoma Cutis

    Open Access Case Report DOI: 10.7759/cureus.3170 Basal Cell Carcinoma with Osteoma Cutis Stella X. Chen 1 , Philip R. Cohen 2 1. School of Medicine, University of California, San Diego 2. Dermatologist, San Diego Family Dermatology, San Diego, USA Corresponding author: Stella X. Chen, [email protected] Abstract Osteoma cutis is the formation of bone within the skin. It can present as either primary osteoma cutis or secondary osteoma cutis. Secondary osteoma cutis is more common and is associated with inflammatory, infectious, and neoplastic disorders, including basal cell carcinoma. A 79-year-old Caucasian man without underlying kidney disease or calcium abnormalities presented with a basal cell carcinoma with osteoma cutis on the chin. Basal cell carcinoma with osteoma cutis has seldom been described; however, the occurrence of this phenomenon may be more common than suggested by the currently published literature. The preferred treatment is surgical excision—with or without using Mohs micrographic technique. When the histopathologic examination reveals bone formation in the skin, clinicians should consider the possible presence of an adjacent malignancy, such as a basal cell carcinoma. Categories: Dermatology, Oncology Keywords: basal, bone, calcium, calcinosis, carcinoma, cell, cutis, ossification, osteoma Introduction Basal cell carcinoma is the most common type of skin cancer. Osteoma cutis is the formation of bone within the skin; it can occur either as a distinct cutaneous entity or associated with other conditions. In primary osteoma cutis, idiopathic ossification occurs and can be congenital, acquired, or related to Albright’s hereditary osteodystrophy and fibrodysplasia ossificans progressiva. Secondary osteoma cutis is more commonly seen and may be associated with infectious, inflammatory, or neoplastic disorders, including basal cell carcinoma.
  • Orbital Osteoma

    Orbital Osteoma

    Orbital Osteoma Gina M. Rogers, MD and Keith D. Carter, MD June 3, 2011 Chief Complaint: Left eyelid mass History of Present Illness: A healthy 20 year-old woman presented to the Oculoplastics Clinic with a 9- month history of left upper lid droopiness. Over the same period of time, she also noted a “bump” at the nasal aspect of her upper eyelid and felt that it was increasing in size. She denied any vision changes, ocular pain, pain with eye movement, or headaches. A complete review of systems was negative. Past Ocular History: Myopia Past Medical History: Non-contributory Medications: None Review of Systems: Negative OCULAR EXAMINATION: Visual acuity with correction: • Right (OD): 20/20 • Left (OS): 20/20 Pupils: Briskly reactive without relative afferent pupillary defect Extraocular motility: Full OU Intraocular pressure: 17 mmHg OD, 18 mmHg OS External Exam Right Left External Normal Fullness of superonasal orbit Exophthalmometry 17 mm 18 mm Palpebral Fissure 10 mm 9 mm Margin Reflex Distance 1 4 mm 4 mm with medial ptosis Palpation Within normal limits Superonasal immobile, hard, smooth lesion Slit lamp exam: Normal OU Dilated fundus exam: Normal disc with 0.2 cup to disc ratio and normal macula, vessels and periphery OU Figure 1: External Photograph demonstrating minimal medial ptosis of the left eyelid Figures 2, 3, and 4: Axial and coronal CT images demonstrating the ill-defined hyperosteotic lesion in the superior medial orbit with extension into the ethmoid sinus COURSE: Given the history of recent growth, the decision was made to perform an excisional biopsy of the lesion.
  • Things That Go Bump in the Light. the Differential Diagnosis of Posterior

    Things That Go Bump in the Light. the Differential Diagnosis of Posterior

    Eye (2002) 16, 325–346 2002 Nature Publishing Group All rights reserved 0950-222X/02 $25.00 www.nature.com/eye IG Rennie Things that go bump THE DUKE ELDER LECTURE 2001 in the light. The differential diagnosis of posterior uveal melanomas Eye (2002) 16, 325–346. doi:10.1038/ The list of lesions that may simulate a sj.eye.6700117 malignant melanoma is extensive; Shields et al4 in a study of 400 patients referred to their service with a pseudomelanoma found these to encompass 40 different conditions at final diagnosis. Naturally, some lesions are Introduction mistaken for melanomas more frequently than The role of the ocular oncologist is two-fold: others. In this study over one quarter of the he must establish the correct diagnosis and patients referred with a diagnosis of a then institute the appropriate therapy, if presumed melanoma were subsequently found required. Prior to the establishment of ocular to have a suspicious naevus. We have recently oncology as a speciality in its own right, the examined the records of patients referred to majority of patients with a uveal melanoma the ocular oncology service in Sheffield with were treated by enucleation. It was recognised the diagnosis of a malignant melanoma. that inaccuracies in diagnosis occurred, but Patients with iris lesions or where the the frequency of these errors was not fully diagnosis of a melanoma was not mentioned appreciated until 1964 when Ferry studied a in the referral letter were excluded. During series of 7877 enucleation specimens. He the period 1985–1999 1154 patients were found that out of 529 eyes clinically diagnosed referred with a presumed melanoma and of as containing a melanoma, 100 harboured a these the diagnosis was confirmed in 936 lesion other than a malignant melanoma.1 cases (81%).
  • Bony Excrescences in Skull Base and Upper Extremity, P

    Bony Excrescences in Skull Base and Upper Extremity, P

    HR Beaks and peaks in adult skeleton, Part I: Bony excrescences in skull base and upper extremity, p. 28-37 J VOLUME 5 | ISSUE 1 PICTORIAL ESSAY MSK Imaging Beaks and peaks in adult skeleton, Part I: Bony excrescences in skull base and upper extremity Zehra Akkaya, Ayşegül Gürsoy Çoruh, Gülden Şahin Ankara University, School of Medicine, Department of Radiology, Ankara, Turkey Submission: 12/12/2019 | Acceptance: 8/3/2020 Abstract Bony protrusions which may be part of normal or vari- lesions are detected incidentally, to being associated ant anatomy or de novo pathologic conditions can have with severe pain and limited range of motion due to im- particular imaging and clinical findings. They can arise pingement and mass effect on the surrounding tissues. as a result of overuse injuries and trauma. Additionally, The purpose of this pictorial review is to overview some some bony spurs may have an evolutionary base. Some common and some infrequent but important bony ex- of them can result from a previous injury whereas some crescences, by emphasising on their clinical importance others are the reason for the injury of neighbouring and differential diagnoses based on their imaging find- structures themselves. Presenting symptoms may also ings. This first part of the review covers the skull base vary accordingly, from being asymptomatic, where the and upper extremity with emphasis on the latter. Key words Imaging/diagnosis; Bone spur; Exostoses; Skull; Radiography; Upper extremity Corresponding Zehra Akkaya, Author, Ankara University, School of Medicine, Department of Radiology, Keklikpinari Guarantor mahallesi Dikmen caddesi 913. Sokak Turtaş Sitesi A-8 Blok No:14 Çankaya-Ankara, Turkey, Email: [email protected] 28 Beaks and peaks in adult skeleton, Part I: Bony excrescences in skull base and upper extremity, p.
  • Enlargement of Choroidal Osteoma in a Child

    Enlargement of Choroidal Osteoma in a Child

    OCULAR ONCOLOGY ENLARGEMENT OF CHOROIDAL OSTEOMA IN A CHILD A discussion and case report of the diagnosis and management of this rare tumor. BY MARIA PEFKIANAKI, MD, MSC, PHD; KAREEM SIOUFI, MD; AND CAROL L. SHIELDS, MD Choroidal osteoma On ultrasonography, the lesion demonstrated a hyper- is a rare intraocular echoic signal with posterior shadowing suggestive of calcifi- bony tumor that cation. On spectral domain enhanced depth imaging optical typically manifests coherence tomography (EDI-OCT), the mass extended under as a yellow-white, the foveola and there was no evidence of choroidal neovas- well-demarcated cular membrane (CNVM) or subretinal fluid (Figure 2). mass with geographic These features were suggestive of choroidal osteoma with pseudopodal mar- documentation of slow, slight enlargement. Given the pre- gins.1-3 This benign tumor predominantly occurs in the served visual acuity and subfoveal location of the osteoma, we peripapillary or papillomacular region, most often in young elected to observe the lesion. Calcium supplementation was women.1,2 Occasionally, choroidal osteoma can simulate an suggested to maintain calcification of the mass, as decalcifica- amelanotic choroidal tumor such as melanoma, nevus, or tion is a known factor predictive of poor visual outcome.6 metastasis.1,2 This tumor can also simulate choroidal inflam- matory disease such as sarcoidosis, tuberculosis, and other DISCUSSION causes of solitary idiopathic choroiditis.2,4 Due to its calcified Choroidal osteoma is a benign calcified tumor that can nature,
  • 2018 Solid Tumor Rules Lois Dickie, CTR, Carol Johnson, BS, CTR (Retired), Suzanne Adams, BS, CTR, Serban Negoita, MD, Phd

    2018 Solid Tumor Rules Lois Dickie, CTR, Carol Johnson, BS, CTR (Retired), Suzanne Adams, BS, CTR, Serban Negoita, MD, Phd

    Solid Tumor Rules Effective with Cases Diagnosed 1/1/2018 and Forward Updated November 2020 Editors: Lois Dickie, CTR, NCI SEER Carol Hahn Johnson, BS, CTR (Retired), Consultant Suzanne Adams, BS, CTR (IMS, Inc.) Serban Negoita, MD, PhD, CTR, NCI SEER Suggested citation: Dickie, L., Johnson, CH., Adams, S., Negoita, S. (November 2020). Solid Tumor Rules. National Cancer Institute, Rockville, MD 20850. Solid Tumor Rules 2018 Preface (Excludes lymphoma and leukemia M9590 – M9992) In Appreciation NCI SEER gratefully acknowledges the dedicated work of Dr. Charles Platz who has been with the project since the inception of the 2007 Multiple Primary and Histology Coding Rules. We appreciate the support he continues to provide for the Solid Tumor Rules. The quality of the Solid Tumor Rules directly relates to his commitment. NCI SEER would also like to acknowledge the Solid Tumor Work Group who provided input on the manual. Their contributions are greatly appreciated. Peggy Adamo, NCI SEER Elizabeth Ramirez, New Mexico/SEER Theresa Anderson, Canada Monika Rivera, New York Mari Carlos, USC/SEER Jennifer Ruhl, NCI SEER Louanne Currence, Missouri Nancy Santos, Connecticut/SEER Frances Ross, Kentucky/SEER Kacey Wigren, Utah/SEER Raymundo Elido, Hawaii/SEER Carolyn Callaghan, Seattle/SEER Jim Hofferkamp, NAACCR Shawky Matta, California/SEER Meichin Hsieh, Louisiana/SEER Mignon Dryden, California/SEER Carol Kruchko, CBTRUS Linda O’Brien, Alaska/SEER Bobbi Matt, Iowa/SEER Mary Brandt, California/SEER Pamela Moats, West Virginia Sarah Manson, CDC Patrick Nicolin, Detroit/SEER Lynda Douglas, CDC Cathy Phillips, Connecticut/SEER Angela Martin, NAACCR Solid Tumor Rules 2 Updated November 2020 Solid Tumor Rules 2018 Preface (Excludes lymphoma and leukemia M9590 – M9992) The 2018 Solid Tumor Rules Lois Dickie, CTR, Carol Johnson, BS, CTR (Retired), Suzanne Adams, BS, CTR, Serban Negoita, MD, PhD Preface The 2007 Multiple Primary and Histology (MPH) Coding Rules have been revised and are now referred to as 2018 Solid Tumor Rules.