2017 Science Research Conference (SRC) Directory

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REGISTER NOW! www.FASEB.org/SRC Invitation to Attend

Dear Prospective Attendee,

On behalf of the FASEB Science Research Conferences program, we would like to invite you to participate in our 2017 conference series.

FASEB SRCs are held annually at several locations worldwide, with an average of 100 to 150 attendees per conference. These intimate settings allow attendees to have in-depth discussions about the science presented, its future, and the contributions they hope to make in their respective fields. Each meeting spans five days, allowing time for established scientists to share their work and for trainees to participate in Meet-the-Expert Sessions. Participants also have the opportunity to present their research either as short-talks or during poster sessions. In addition, the SRCs provide a welcoming environment for scientific discourse, collaboration, and opportunities to mentor the next generation of researchers. Please join more than 4,000 researchers who will be participating in one or more of the 31 conferences this year. We look forward to seeing you!

John D. Barnes Interim Executive Director, FASEB

SRC Conferences for 2017

Autoimmunity Mechanisms in Plant Development Protein Kinases and Protein The Biology and Chemistry of Vision Mitochondrial Biogenesis and Dynamics Phosphorylation The Biology of Cilia and Flagella in Health, Disease and Aging Protein Lipidation: Enzymology, Signaling and Therapeutics From Unfolded Proteins in the Mobile DNA in Mammalian Genomes Endoplasmic Reticulum (ER) to Disease Molecular Mechanisms of Immune Cell Rapid Signaling and Genomic Steroid Development and Function Hormone Actions in Health Gastrointestinal Tract XVII: Current and Disease Biology of the GI Tract, Mucosa, Molecular Pathogenesis: Mechanisms of Microbiota, and Beyond Infectious Disease Regulation and Function of Small GTPases Genetic Recombination and Genome Molecular, Physiological and Rearrangements Therapeutic Studies of Intestinal Lipid Reversible Acetylation in Health and Disease Glucose Transport: Gateway for Transport and Metabolism Metabolic Systems Biology A Multidisciplinary Approach To Signal Transduction in the Immune System GRKs and Arrestins: From Structure to Addressing Health Disparities and Disease Inequities in the U.S.: Cardiovascular TGF-ß Superfamily: Signaling in Diseases (NEW) Development and Disease Growth Hormone/Prolactin Family in Biology and Disease NAD+ Metabolism and Signaling 2017 Hematologic Malignancies Origins and Benefits of Biologically Active Components in Human Milk Ion Channel Regulation Polycystic Kidney Disease: Challenges, Lysophospholipid and Related Differing Viewpoints and Mediators – From Bench to Clinic Ways Forward Mechanism and Regulation of Protein Aggregation in Health and Prokaryotic Transcription Disease

2 FASEB Science Research Conferences 2017 Register Today!

FASEB Science Research Community We Strive For A Diverse Pick a Community Conferences (SRCs) are a The SRCs are held annually and are FASEB, as a longtime recipient organization continuing series of small, focused on building communities of of federal funding support from the National interest around critical research topics. This intimate interdisciplinary Institutes of Health/National Institute of encourages collaboration and mentoring. General Medical Sciences (NIH/NIGMS) conferences that explore new and other federal agencies, has a strong approaches in research areas and well documented commitment in Registration Information helping to inspire and develop a diverse and undergoing rapid scientific inclusive biomedical research workforce and advances. Registration Types community. Single Occupancy: includes a single Career-Oriented Workshops guest room for one attendee. We invite you to join FASEB Science Research Conferences more than 4,000 fellow Double Occupancy with Another include a biomedical research workforce development workshop and/or a career- attendees at these exciting Attendee: includes a double occupancy room shared with another paid attendee. oriented workshop for trainees (graduate and engaging conferences students, postdoctoral fellows) and early- exploring and discussing Double Occupancy with Guest: career investigators. These workshops are includes a double occupancy room shared designed to help prepare trainees and topics in your field. with your personal invited guest. Guests early-career investigators for a variety of receive meals, and lodging. Guests may not career options in the modern biomedical attend general sessions or poster sessions. research workforce through broadening Why Attend  Offsite Attendee: The offsite their career and skill development outside traditional training. They allow opportunities FASEB offers an all-inclusive registration registration fee includes meals and meeting ▶▶ to promote career/skill development, fee, which includes meals, lodging, and fees. If you choose off-site registration, you mentoring, networking, and interaction meeting fees. are responsible for securing and paying for your lodging, as well as local ground among the SRC participants. ▶▶All SRCs are organized by leading investigators in their fields of expertise. transportation to and from the meeting. Meet The Expert Sessions ▶▶The SRCs spur innovation and the FASEB SRCs include Meet-The-Expert exchange of knowledge. Registration Fees sessions for junior investigators. Junior ▶▶Registration fees vary depending upon investigators’ work will be presented to ▶▶The small size of the conference is your conference location and registration allow opportunities for them to promote designed to promote interaction through type. If you register after the early-bird interaction with more senior participants of Poster Sessions, Meet-the-Expert Sessions, registration deadline, an additional $150 the conference. and career development workshop. will be added to the registration fee. ▶▶The SRCs offer a wide variety of Poster Sessions for Junior conference topics in the biomedical field ▶▶Fees cannot be prorated or discounted Investigators across the U.S. and around the world. due to contractual arrangements with Junior investigators' work will be presented venues. to allow opportunities for them to promote ▶▶Register early to avoid late fees. interaction with more senior participants. ▶▶Advanced registration is required. On-site registration is not permitted. ▶▶Only attendees who have registered and Visit Our submitted a CV may participate in the Website conference. ▶▶Abstracts are due at the time of registration, if interested in presenting a poster or short talk. ▶▶Conference registration closes four weeks Need help making the prior to the start of the conference. case to attend an SRC See page 5 for registration fees. to your boss? Visit the Attendee Information page, where you can download a letter to your boss template.

Register Now! www.faseb.org/SRC 3 General Information

Registration and Payment If I’ve submitted an abstract, will I fee includes the conference and all meals present a poster? but enables attendees to book their own What does the registration fee include? Yes. A poster presentation schedule will be listed accommodations). Both the FASEB and venue The single and double occupancy attendee in the program provided at the conference. websites include information on nearby registration fees include five nights of lodging off-site accommodations that can assist (Sunday through Thursday, with checkout How do I indicate that I want to give a attendees with locating licensed child care on Friday morning), all meals (five breakfasts, short talk at the conference? providers and daycare services. The venue five lunches, and five dinners), and access When registering select the “short talk” management may also provide any assistance to all scientific sessions and posters. The button. Your information will be shared with to attendees regarding child/family care off‑site registration fee includes all meals (five the conference organizer. The organizer will issues or concerns. Each attendee is also breakfasts, five lunches, and five dinners), and contact you if you are selected to present your encouraged to contact FASEB with any special access to all scientific sessions and posters. paper. You will also be allowed to present your needs that they may have. poster during the poster sessions. What forms of payment are accepted? FASEB only accepts Visa, MasterCard, and Cancellation American Express. Lodging What is the cancellation policy? What do single occupancy, double Cancellations received before the cancellation I cannot stay at the conference for the occupancy, and off-site lodging mean? entire time. Can the registration fee be deadline will receive a full refund less a Single occupancy – one (1) registered prorated? $250.00 cancellation fee. See the cancellation conference attendee to a guest room. FASEB is contractually obligated to pay for five deadline date for your conference. There will nights of lodging (official conference dates only) Double occupancy – two (2) registered be no refunds issued if the cancellation form is at each conference regardless of the number of conference attendees sharing one guest room received after the cancellation deadline date. with two beds. Each attendee pays the double nights an attendee chooses to stay at the venue. I cannot attend the conference; can I occupancy registration fee. Therefore, registration fees cannot be pro-rated. send someone in my place? Off-site – the attendee is responsible for Substitutions are not allowed. Each attendee International Attendees arranging for and paying for their own lodging must register and be approved to attend the How can I get an official letter of arrangements. conference based on their credentials. invitation to attend the conference? I need to arrive a day before the During the registration process, there is a conference starts and/or stay a day Who to Contact check box option for a letter of invitation. after the conference has concluded. FASEB SRC Staff Mark this box, and a letter of invitation will How do I make arrangements for the CMP extra night(s)? Robin Crawford, be sent to you as part of your confirmation Conference Manager materials once your registration and payment After you receive your lodging confirmation [email protected] have been processed by the online system. from FASEB, you must contact the venue directly to make arrangements for the extra nights Kristen Hagy, CMP of lodging. You are responsible for paying for Conference Manager Abstracts and Posters [email protected] Do I have to submit an abstract with my any additional nights. Please note: in Vermont, Trina Eacho registration? additional nights at the dorms are not possible. You must make a reservation at a local hotel. Conference Coordinator No. Submitting an abstract is optional unless Research the city of your conference for [email protected] you want to be considered for a poster session additional venue options at www.faseb. or short talk. Pippa O’Shea org/src. Conference Assistant I need to revise my abstract. Is this [email protected] possible? Child and Family Care Fundraising/Sponsorship Abstracts can be revised and changed until Resources Sherri-Gae Scott, Ph.D. 45 days before the start of your conference. Are child care and/or family resources Grants Proposal Manager Refer to your registration confirmation email [email protected] for instructions. are available? FASEB provides detailed information for each Mailing Address Can I register and submit my abstract conference site on the Science Research FASEB Science Research Conferences after the early-bird deadline date? Conference (SRC) website and also provides 9650 Rockville Pike Yes, as long as there is space available at the venue information directly to each attendee. Bethesda, MD 20814 conference. A late fee of $150.00 will be charged. Although FASEB does not provide child care [email protected] What is the latest date to submit an services, attendees are welcome to have (301) 634-7010 abstract? guests (including spouses, children, nannies and babysitters) accompany them to the Abstract deadline for inclusion in the program conference to provide such care. FASEB and consideration for a short talk is the last offers an alternative off-site registration fee day to register for the conference. See page 5. at all conferences, to accommodate those with special family care needs (the off-site

4 FASEB Science Research Conferences 2017 Important Deadlines & Registration Fees Deadlines Conference Early Bird Registration Last Day to Conference Title Dates 2017 Deadline Register

Mitochondrial Biogenesis and Dynamics in Health, Disease and Aging May 21 – 26, 2017 April 20, 2017 April 28, 2017 MAY GRKs and Arrestins: From Structure to Disease June 11 – 16, 2017 May 3, 2017 May 11, 2017

Protein Aggregation in Health and Disease June 11 – 16, 2017 May 3, 2017 May 11, 2017

Rapid Signaling and Genomic Steroid Hormone Actions in Health June 11 – 16, 2017 May 3, 2017 May 11, 2017 and Disease

Regulation and Function of Small GTPases June 11 – 16, 2017 May 3, 2017 May 11, 2017

Mobile DNA in Mammalian Genomes June 18 – 23, 2017 May 7, 2017 May 18, 2017

JUNE From Unfolded Proteins in the Endoplasmic Reticulum (ER) to Disease June 18 – 23, 2017 May 7, 2017 May 18, 2017

Signal Transduction in the Immune System June 18 – 23, 2017 May 7, 2017 May 18, 2017

The Biology and Chemistry of Vision June 25 – 30, 2017 May 14, 2017 May 25, 2017

Mechanism and Regulation of Prokaryotic Transcription June 25 – 30, 2017 May 14, 2017 May 25, 2017 Polycystic Kidney Disease: Challenges, Differing Viewpoints and June 25 – 30, 2017 May 14, 2017 May 25, 2017 Ways Forward Autoimmunity July 9 – 14, 2017 May 28, 2017 June 8, 2017

Ion Channel Regulation July 9 – 14, 2017 May 28, 2017 June 8, 2017

Molecular Pathogenesis: Mechanisms of Infectious Disease July 9 – 14, 2017 May 28, 2017 June 8, 2017

NAD+ Metabolism and Signaling 2017 July 9 – 14, 2017 May 28, 2017 June 8, 2017

TGF-ß Superfamily: Signaling in Development and Disease July 9 – 14, 2017 May 21, 2017 June 8, 2017

The Biology of Cilia and Flagella July 16 – 21, 2017 June 4, 2017 June 15, 2017

Genetic Recombination and Genome Rearrangements July 16 – 21, 2017 June 4, 2017 June 15, 2017

Glucose Transport: Gateway for Metabolic Systems Biology July 16 – 21, 2017 June 4, 2017 June 15, 2017

Origins and Benefits of Biologically Active Components in Human Milk July 16 – 21, 2017 May 28, 2017 June 15, 2017

JULY Protein Lipidation: Enzymology, Signaling and Therapeutics July 16 – 21, 2017 June 4, 2017 June 15, 2017

A Multidisciplinary Approach To Addressing Health Disparities and Inequities in the U.S.: July 23 – 28, 2017 June 11, 2017 June 22, 2017 Cardiovascular Diseases (NEW)

Growth Hormone/Prolactin Family in Biology and Disease July 23 – 28, 2017 June 11, 2017 June 22, 2017

Hematologic Malignancies July 23 – 28, 2017 June 11, 2017 June 22, 2017

Molecular, Physiological and Therapeutic Studies of Intestinal Lipid Transport and July 23 – 28, 2017 June 11, 2017 June 22, 2017 Metabolism Gastrointestinal Tract XVII: Current Biology of the GI Tract, Mucosa, Microbiota, and Beyond July 30 – August 4, 2017 June 18, 2017 June 29, 2017 Mechanisms in Plant Development July 30 – August 4, 2017 June 18, 2017 June 29, 2017

Molecular Mechanisms of Immune Cell Development and Function July 30 – August 4, 2017 June 18, 2017 June 29, 2017

Reversible Acetylation in Health and Disease August 6 – 11, 2017 June 25, 2017 July 6, 2017

Protein Kinases and Protein Phosphorylation August 6 – 11, 2017 June 18, 2017 July 6, 2017

AUGUST Lysophospholipid and Related Mediators – From Bench to Clinic August 20-24, 2017 July 9, 2017 July 20, 2017 Registration Fees (in USD) Additional Guest Double with Double with Off-site Conference Location Single (3rd guest, ages 10 Attendee Guest Attendee & over) Big Sky, MT, Big Sky Resort $1,750 $1,400 $2,240 $840 $1,095 New Orleans, LA, New Orleans Marriott $ 1,800 $ 1,445 $2,460 $1,015 $1,095 Saxtons River, VT, Vermont Academy $ 1,165 $ 1,015 $1,710 $695 $797 Scottsdale, AZ, Scottsdale Plaza Resort $ 1,600 $ 1,400 $2,370 $970 $1,095 Snowmass Village, CO, Base Village Conference Center $ 1,529 $ 1,250 $2,090 $840 $1,095 Steamboat Springs, CO, Steamboat Grand Resort $ 1,400 $ 1,250 $2,150 $900 $1,095 West Palm Beach, FL, Marriott West Palm Beach $ 1,600 $ 1,350 $2,320 $970 $1,095 Cambridge, England, Robinson College $ 1,600 n/a n/a n/a $1,095 Lisbon, Portugal, Marriott Lisbon Hotel $ 1,800 $ 1,530 $2,540 $1,010 $1,095

Register Now! www.faseb.org/SRC 5 2017 Science Research Conferences Autoimmunity July 9 – 14, Saxtons River, VT – Vermont Academy

The SRC for Autoimmunity has an uninterrupted tradition of over 20 Highlights Important Deadlines years and offers a broad overview of recent advances in the field of ▶▶Career Development Workshop Early Bird: May 28, 2017 autoimmunity in a highly interactive environment. Understanding ▶▶Meet-the-Experts sessions Last Day to Register: June 8, 2017 immune tolerance and its breakdown is necessary to treat autoimmune ▶▶Short talks selected from diseases such as lupus, multiple sclerosis, uveitis, type 1 diabetes, submitted abstracts arthritis, inflammatory bowel disease, and many others. We bring Transportation & together basic scientists with clinicians and industry experts to present Keynote Speakers Lodging and discuss new insights into the triggers, pathogenesis and therapy of Christophe Benoist, Official Conference Lodging: chronic inflammatory and autoimmune disease. Harvard Medical School Vermont Academy, 10 Long Walk, Saxtons River, VT 05154 Eight major sessions will cover a broad range of topics in development, Conference Organizers Airport Information: Vermont pathogenesis and therapy of autoimmune disease, starting with the Academy in Saxtons River, Joe Craft, Yale University effects of genetics and environment, through the role of innate and Vermont is 130 miles from Logan adaptive immune elements as well as the tissue itself, the role of Alessandra Pernis, Hospital International Airport (BOS) in Boston, for Special Surgery commensal microbiome and metabolism, and finally translational Massachusetts and 110 miles from Bradley International Airport (BDL) research and clinical approaches. Each thematic session will feature 4 near Hartford, Connecticut. invited speakers and two talks selected from submitted abstracts. Participants have ample opportunity for interaction and discussion. Spontaneous mingling of junior and established scientists will be strengthened by meet-the-speaker sessions that allow discussions of both career issues and science. The intimate atmosphere, strong Register emphasis on communication and discussion, and a really close Now! interaction between senior and junior scientists makes this conference unique and memorable to participants.

The Biology and Chemistry of Vision June 25 – 30, Steamboat Springs, CO – The Steamboat Grand Hotel

This SRC is the only meeting of its kind specifically dedicated to the Highlights Important Deadlines field of photoreceptor biology. The scientific program reflects the multi- ▶▶Datablitz presentations Early Bird Deadline: May 14, 2017 disciplinary nature of this field, encompassing classical biochemistry and highlighting presented posters Last Day to Register: May 25, 2017 structural biology as well as modern imaging techniques and molecular ▶▶Meet-the-Experts sessions therapeutic approaches. Specific session topics will range from ▶▶Career Development Workshop photoreceptor physiology and RPE cell biology to the immune respose Transportation & to photoreceptor degeneration. The scientific program will include two Keynote Speakers Lodging keynote addresses and invited talks, as well as numerous short talks and Samuel Jacobson, University of Official Conference Lodging: DataBlitz presentations that will be selected from submitted abstracts. Pennsylvania The Steamboat Grand Resort, 2300 Paul Sieving, National Eye Mt Werner Cir, Steamboat Springs, The meeting schedule and venue are designed to present the most CO 80487. Institute exciting scientific advances in an atmosphere that encourages informal Airport Information: The interactions and collaborations. All attendees will have the opportunity Conference Organizers Steamboat Grand Resort is 22 miles to present a poster, and additional recreational activities will be available from the Steamboat-Yampa Valley Marie Burns, UC Davis to all participants to foster the exchange of ideas and formulate new Regional/Hayden Airport (HDN) David S. Williams, UCLA and 155 miles northwest of Denver collaborations. It is anticipated that there will be funds available to International Airport (DIA). support early career researcher attendance. Parking: Overnight parking fees for summer: $5.00 Ski Time Spare Parking, $10.00, self-parking in hotel underground garage, $15.00 valet.

Register Now!

6 FASEB Science Research Conferences 2017 Science Research Conferences 2017 The Biology of Cilia and Flagella July 16 – 21, Scottsdale, AZ – Scottsdale Plaza Resort

Research on the biology of the cilium has seen explosive growth as Highlights Important Deadlines its essential roles in cell signaling and human disease are now well ▶▶Meet-the-Experts sessions Early Bird Deadline: June 4, 2017 recognized. Sensory cilia act as cellular antennas that transduce key ▶▶A Biomedical Research Last Day to Register: June 15, developmental and physiological signals while motile cilia play an Workforce Development 2017 essential role in development and organ function. Ciliary diseases Workshop or ciliopathies include the most common life-threatening inherited ▶▶Short talks selected from Transportation & disease of humans, Polycystic Kidney Disease, as well as retinitis submitted abstracts Lodging pigmentosa, obesity, and mental retardation; all components of the Official Conference Lodging: human syndromic pathologies Nephronophthisis, Bardet-Biedl, Meckel Keynote Speaker Scottsdale Plaza Resort, 7200 North Scottsdale Road, Scottsdale, AZ Gruber, and Joubert syndromes. Cilia regulate hedgehog signaling, Bradley Yoder, University of 85253 which is essential for development and has been implicated in PKD as Alabama, Birmingham Airport Information: The well as basal cell carcinomas and other cancers. Despite advances in Conference Organizers closest airport is the Sky Harbor our understanding of cilia biology, important questions remain about International Airport (PHX) in Iain Drummond, MGH / how cilia are assembled, how they function, and how ciliary signal Phoenix. The airport is approximately Harvard Medical School transduction impacts so many developmental events. 30 minutes away. The Scottsdale Jagesh Shah, Harvard Plaza Resort offers an airport shuttle This SRC provides an intellectual nexus for a broad range of cilia Medical School that runs daily from 5am until 9pm, every 30 minutes. The cost is $23 investigators including human geneticists, cell, molecular, and Tamara Caspary, Emory per person each way. developmental biologists, biochemists, and physician scientists. Cutting- University School of Medicine edge research presentations provide a current view of technological advances in ciliary imaging, signal transduction, structural biology, and human disease. The meeting also showcases innovative applications Register of model organisms, such as Drosophila, C. elegans, and zebrafish for Now! fundemental discovery and high-throughput screening approaches that impact therapeutic assay development.

From Unfolded Proteins in the Endoplasmic Reticulum (ER) to Disease June 18 – 23, Saxtons River, VT – Vermont Academy

This SRC is a unique scientific conference, which focuses on the Highlights Important Deadlines endoplasmic reticulum (ER) and its functions. The purpose of the ▶▶Keynote Lecture meeting is to merge recent developments in molecular biology, cell Early Bird Deadline: May 7, 2017 “Pathophysiology of Protein Last Day to Register: May 18, 2017 biology, genetics, and physiology aimed at unraveling the complexities Folding” of secretory protein folding, ER stress pathways, lipid signaling, and ▶▶Poster Flash-Talk Sessions Transportation & ER membrane biology, and how failure of these processes lead ▶▶Career Development Workshop Lodging to pathologies and disease. This meeting will include talks from Official Conference Lodging: outstanding scientists, both invited and selected from poster abstracts. Keynote Speaker Vermont Academy, 10 Long The meeting is known for its active discussions, not only during the David Ron, Cambridge Institute Walk, Saxtons River, VT 05154 presentation session, but also during the free afternoons, and especially for Medical Research Airport Information: Vermont during the poster sessions. Posters will remain on display during most of Ineke Braakman, Utrecht Academy in Saxtons River, the conference and a selection will be advertised in oral poster pitches. University Vermont is 130 miles from Logan The venue, Vermont Academy, is excellently suited for the mingling of International Airport (BOS) in Boston, Conference Organizers Massachusetts and 110 miles from junior and established scientists, which will be strengthened by meet- Bradley International Airport (BDL) the-speaker sessions that allow discussions of both career issues and Elizabeth Miller, near Hartford, Connecticut. science. MRC Laboratory of Molecular Biology Reid Gilmore, University of Massachusetts Medical School Register Now!

Register Now! www.faseb.org/SRC 7 2017 Science Research Conferences Gastrointestinal Tract XVII: Current Biology of the GI Tract, Mucosa, Microbiota and Beyond July 30 – August 4, Steamboat Springs, CO – The Steamboat Grand Hotel

This SRC spans the entire range of investigation in gastroenterology, from Highlights Important Deadlines molecules to cellular interactions to microbiota to intact organisms. It ▶▶Career Development Workshop Early Bird Deadline: June 18, 2017 focuses on comparing and contrasting normal biology/physiology with ▶▶Short talks selected from Last Day to Register: June 29, 2017 disease pathophysiology and on providing a clinical context for basic submitted abstracts research observations. Eight thematic sessions have been organized ▶▶Quick-shot “ePoster” sessions Transportation & to encompass rapidly developing areas in GI research: Monitoring and ▶▶Meet-the-Experts sessions Lodging Responding to the Microbiota; Mucosal Injury and Restitution; Microbiota- Keynote Speaker Official Conference Lodging: Host Crosstalk; Signaling Mechanisms Coordinating Gastrointestinal Ramnik Xavier, Massachusetts Steamboat Grand Resort, 2300 Mt Werner Cir, Steamboat Springs, CO 80487. Homeostasis and Response to Inflammation;) The Stem Cell Niche, General Hospital Airport Information: The Inflammation, and Cancer; Transport and Barrier;) Host-Pathogen Conference Organizers Interactions; and Novel Approaches to GI Biology. The format is designed Steamboat Grand Resort is 22 miles Conference Organizers from the Steamboat-Yampa Valley to facilitate the rapid translation of basic biology discoveries into new Regional/Hayden Airport (HDN) medically relevant approaches to human disease. Andrew S. Neish, Emory and 155 miles northwest of Denver University School of Medicine In addition to the platform talks from established investigators and International Airport (DIA). Gail A. Hecht, Loyola early-career rising stars, a number of abstracts from trainees and young Parking: Overnight parking fees University for summer: $5.00 Ski Time Spare investigators will be selected for short talk presentations, and two poster University Parking, $10.00, self-parking in hotel and two oral presentation sessions of rapid-fire “ePoster” presentations Mark R. Frey, of Southern California and underground garage, $15.00 valet. will be held to maximize the number of investigators given exposure. Children’s Hospital Los Angeles Thus, this conference will not only provide a strong overview of cutting edge GI research but also provide a critical venue for trainees and early Register career investigators to showcase their work. Now!

Genetic Recombination and Genome Rearrangements July 16 – 21, Steamboat Springs, CO – The Steamboat Grand Hotel

This SRC presents progress in research on diverse aspects of genetic Highlights Important Deadlines recombination, a critical process that maintains integrity of the genome ▶▶Keynote Address “ Protecting Early Bird Deadline: June 4, 2017 and that ensures the faithful transmission of the genome between the Genome by Homologous Last Day to Register: June 15, generations. This conference focuses on the study of recombination Recombination” 2017 mechanisms, the impact of recombination on genome integrity, and ▶▶Career Development Workshop the influence of other DNA processes on recombination. Many of the ▶▶Meet-the-Experts sessions Transportation & recent advances in understanding recombination in normal, pathological, Lodging and environmentally stressed contexts have emerged through new Keynote Speakers Official Conference Lodging: combinations of experimental approaches spanning biochemistry, Maria Jasin, Memorial Sloan Steamboat Grand Resort, 2300 Mt Werner Cir, Steamboat Springs, CO biophysics, genetics, genomics, and cytology. The agenda reflects the Kettering Cancer Center 80487. diversity of approaches currently used and is specifically geared toward Conference Organizers Airport Information: The identifying the emerging technologies and concepts that are moving Tanya Paull, The University of Steamboat Grand Resort is 22 miles the field forward. The meeting will focus on new, unpublished data in Texas at Austin from the Steamboat-Yampa Valley Regional/Hayden Airport (HDN) the field and will highlight connections between recombination and Scott Keeney, Memorial and 155 miles northwest of Denver other cellular processes, including transcription, replication, cell cycle Sloan Kettering Cancer Center progression, and other branches of DNA repair. There will be presentations International Airport (DIA). by researchers using diverse model organisms including bacteria, fungi, Parking: Overnight parking fees for summer: $5.00 Ski Time Spare flies, nematodes, and mammalian cells, as well as in vitro biochemistry Parking, $10.00, self-parking in hotel and structural biology. The meeting will foster collaboration between underground garage, $15.00 valet. researchers worldwide who are interested in the basic and clinical aspects of recombinational repair, particularly in cancer biology. There will be many opportunities for interaction between established Register investigators and scientists who are new to the field, and a significant Now! number of the plenary speakers will be chosen from submitted abstracts.

8 FASEB Science Research Conferences 2017 Science Research Conferences 2017 Glucose Transport: Gateway for Metabolic Systems Biology July 16 – 21, Snowmass, CO – Base Village Conference Center

This SRC will provide a lively mix of glucose transporter biology, Highlights Important Deadlines metabolic regulation, and systems biology methods with multiple ▶▶Career Development Workshop Early Bird Deadline: June 4, 2017 lectures featuring disease translational themes. This SRCs was ▶▶Meet-the-Experts sessions Last Day to Register: June 15, originally launched in the early 1990s in recognition of the cloning and ▶▶Short talks selected from 2017 characterization of a subset of the major glucose transporter isoforms. submitted abstracts It has continued to feature important advances in glucose transporter Transportation & biology, but has also evolved to embrace emergent topics in metabolic Keynotes Speakers Lodging control mechanisms as related to chronic diseases and conditions such Christopher Newgard, Official Conference Lodging: as obesity, diabetes, and cardiovascular disease. Recent progress in W. David and Sarah W. Stedman Base Village Conference Center, 84 Carriage Way, Snowmass Village, CO this area has been explosive, and this SRC is timely in helping to fully Distinguished Professor of 81615. appreciate the significance of recent developments. A particular focus in Pharmacology and Cancer Biology, Duke University School Airport Information: Snowmass 2017 will be neuroendocrine regulation of metabolism, liver metabolism, of Medicine Village is just ten miles from the and skeletal muscle metabolism in health and disease, featuring Aspen-Pitkin County Airport (ASE), leading scientists in the field along with faculty in the early stages of Conference Organizers and 220 miles west of the Denver their careers. The SRC’s themes align well with challenges faced by the International Airport (DEN) Ann Louise Olson, pharmaceutical and biotech industries in identifying new therapeutic University of Oklahoma Health targets to combat tractable disease mechanisms. Sciences Center The conference has consistently attracted major leaders in these fields Scott Summers, University as well as emergent young scientists. More than 40 scientists worldwide of Utah have been invited to speak at the meeting. A dozen prominent scientists will serve as session chairs and discussion leaders. In addition, Register approximately 16 junior trainees will present short talks from abstracts. Now! There will also be several poster sessions and an open mike session to present exciting data for discussion.

GRKs and Arrestins: From Structure to Disease June 11 – 16, Saxtons River, VT – Vermont Academy

This SRC provides an interactive forum to discuss current developments Highlights Important Deadlines in the G protein-coupled receptor (GPCR) field with a particular focus ▶▶Keynote Addresses by Nobel Early Bird Deadline: May 3, 2017 on GPCR kinases (GRKs) and arrestins. GRKs and arrestins work together Laureates Robert J. Lefkowitz Last Day to Register: May 11, 2017 to regulate GPCR signaling by reducing the ability of receptors to and Brian Kobilka couple with heterotrimeric G proteins and by targeting active receptors ▶▶Career Development Workshop Transportation & for endocytosis. These mechanisms are important for returning cells ▶▶Meet-the-Experts sessions Lodging to their physiological resting states. In addition, GRKs and arrestins Official Conference Lodging: are also thought to initiate alternative signaling pathways and to Keynote Speakers Vermont Academy, 10 Long play prominent roles in addiction, cardiovascular disease and other Robert J. Lefkowitz, Duke Walk, Saxtons River, VT 05154 pathological conditions. Consequently there is a major effort to identify University School of Medicine Airport Information: Vermont small molecules that bias GPCRs for or against GRK/arrestin-mediated Brian K. Kobilka, Stanford Academy in Saxtons River, University School of Medicine Vermont is 130 miles from Logan pathways or that prevent overcompensation by GRKs and arrestins. International Airport (BOS) in Boston, The overarching goal of the meeting is to bring together as many Conference Organizers Massachusetts and 110 miles from scientists working on diverse aspects of GRK/arrestin signaling as possible Bradley International Airport (BDL) Jeffrey Benovic, Thomas near Hartford, Connecticut. in order to facilitate the exchange of novel findings and to stimulate Jefferson University the generation of new hypotheses, collaborations, and approaches. The Federico Mayor, Jr., structural and functional mechanisms of GRKs and arrestins, as well as their Universidad Autónoma Madrid- roles in biased/non-canonical signaling by GPCRs, in the actions of drugs Centro de Biología Molecular of abuse, in cardiovascular disease and in cancer will be major highlights “Severo Ochoa” of the meeting. Sessions devoted to these topics will foster further studies to combat addiction and disease with the ultimate objective of positively influencing human health. There are many opportunities available for attendees to give oral and poster presentations as well as optional Register recreational activities to foster the exchange of ideas and formulate new Now! collaborations. It is anticipated that there will be some funds available to support attendance by early career researchers.

Register Now! www.faseb.org/SRC 9 2017 Science Research Conferences Growth Hormone/Prolactin Family in Biology and Disease July 23 – 28, Steamboat Springs, CO – The Steamboat Grand Hotel

This SRC will bring together international scientists from academia and Highlights Important Deadlines industry for lively discussions on the latest developments in the growth ▶▶Career Development Workshop Early Bird Deadline: June 11, 2017 hormone (GH)/prolactin (PRL) family of hormones and their clinical ▶▶Invited talks on pioneering Last Day to Register: June 22, applications. Beyond their classic roles in growth and lactation, these related investigations of GH/PRL tissue 2017 hormones are increasingly recognized regulators of metabolism, stem cells, specific actions, mediators, aging, behavior, cancer, and perinatal health of both mother and child, via synthesis/secretion innovative Transportation & actions on diverse target tissues. They also influence major associated health therapeutic targets and Lodging approaches. problems, such as obesity, diabetes, aging, mental health and multiple Official Conference Lodging: The cancers. We will bring together senior and junior investigators working on ▶▶Short talks selected from Steamboat Grand Resort, 2300 Mt submitted abstracts Werner Cir, Steamboat Springs, CO all aspects of these hormones, from cell biology, genetics, developmental 80487. biology, neurobiology, metabolism, physiology, to their clinical and Keynote Speakers Airport Information: The agricultural applications. Together, we will increase our understanding of Cynthia Kenyon, Calico Labs Steamboat Grand Resort is 22 miles how GH/PRL family proteins modulate health and disease processes, forge from the Steamboat-Yampa Valley new collaborations, and accelerate the discovery of new pharmacologic Conference Organizers Regional/Hayden Airport (HDN) approaches. Speakers from the GH/PRL community and related fields from Linda Schuler, University of and 155 miles northwest of Denver around the world will share breaking data on a variety of cutting edge topics Wisconsin-Madison International Airport (DIA). Overnight parking fees including genetic mutations in synthesis and signaling pathways, newly Rhonda Kineman, University of Parking: for summer: $5.00 Ski Time Spare identified targets, novel mediators and nodes of critical crosstalk with other Illinois at Chicago Parking, $10.00, self-parking in hotel players, pituitary stem cells, interactions between peripheral hormones, underground garage, $15.00 valet. hypothalamus and brain, and new drug targets/pre-clinical studies. Trainees are especially welcomed. Many short talks, poster, and travel awards will be selected from submitted abstracts. In addition to a formal “Meet the Experts” session, there also will be many informal opportunities Register to engage with international leaders in a relaxed setting. This unique Now! opportunity will ensure fruitful discussions, support career mentoring and help to foster new collaborations.

Hematologic Malignancies July 23 – 28, Saxtons River, VT – Vermont Academy

This SRC bring together biochemists, geneticists, molecular biologists, Highlights Important Deadlines and clinicians interested in the pathophysiology of the leukemias ▶▶Career Development Workshop Early Bird Deadline: June 11, 2017 and lymphomas, and the development of novel therapies for these ▶▶Meet-the-Experts sessions Last Day to Register: June 22, diseases. Leukemia and lymphoma has provided a number of key ▶▶Short talks selected from 2017 paradigms for molecularly targeted cancer therapy, as illustrated by the submitted abstracts remarkable success of all-trans-retinoic acid for the treatment of acute Transportation & promyelocytic leukemia and tyrosine kinase inhibitor therapy for chronic Keynote Speaker Lodging myelogenous leukemia. New and promising small-molecule compounds Jay Bradner, Novartis Official Conference Lodging: and antibodies targeting epigenetic regulators, surface receptors and Ari Melnick, Cornell University Vermont Academy, 10 Long Walk, Saxtons River, VT 05154. downstream signaling pathways are currently under development and will be discussed at this meeting. Added to these examples of targeted Conference Organizers Airport Information: Vermont Academy in Saxtons River, therapy, immunotherapy, including checkpoint inhibition and modified Iannis Aifantis, NYU School Vermont is 130 miles from Logan T cell-based therapies have emerged as important future anti-leukemia/ of Medicine International Airport (BOS) in Boston, lymphoma treatments. The meeting will cover a broad range of topics, Kimberly Stegmaier, Massachusetts and 110 miles from including hematopoietic stem cell differentiation, identification and Dana-Farber Cancer Institute Bradley International Airport (BDL) study of novel oncogenes and tumor suppressors, mechanisms of action near Hartford, Connecticut. of products of chromosomal translocations, normal and pathologic signaling in hematopoietic cells, aberrant epigenetic/transcriptional control, genomics of hematological malignancies, the role of tumor microenvironment, and the development of new experimental models of hematologic malignancies. Register Now!

10 FASEB Science Research Conferences 2017 Science Research Conferences 2017 Ion Channel Regulation July 9 – 14, Steamboat Springs, CO – The Steamboat Grand Hotel

This SRC will highlight the latest research on mechanisms of ion channel Highlights Important Deadlines regulation and its impact on the physiology of diverse cell types. It seeks ▶▶Special Session: Celebrating Early Bird Deadline: May 28, 2017 to stimulate discourse, seed new ideas, and facilitate collaboration in William A. Caterall: 40 years of Last Day to Register: June 8, 2017 ways that will accelerate new discoveries about ion channel regulation Ion Channel Research at both the basic and translational levels. It will also fuel discovery by ▶▶Career Development Workshop Transportation & bringing together scientists applying all of these diverse technical and ▶▶Keynote Lecture: Jeanne Lodging conceptual strategies to study ion channel regulation across a range Nerbonne, Washington Official Conference Lodging: of different biological systems. The program consists of nine scientific University “Diversity in Cardiac Steamboat Grand Resort, 2300 Mt sessions and a keynote address, as well as two breakout sessions and Ion Channel Regulatory Werner Cir, Steamboat Springs, CO Mechanisms” 80487. lunches focused on trainee career development. Scientific sessions are organized around themes, rather than ion channel subtype, to foster Airport Information: The Keynote Speaker Steamboat Grand Resort is 22 miles crosstalk between fields, and will cover a variety of topics including Jeanne Nerbonne, Washington from the Steamboat-Yampa Valley sensory systems and pain; regulation of neuronal excitability; regulation University Regional/Hayden Airport (HDN) of gene expression; ion channels in disease; ion channel structure and and 155 miles northwest of Denver drug development; recent advances in imaging and ion channel cell Conference Organizers International Airport (DIA). biology; regulation of the cardiovascular system and skeletal muscle; Mark L. Dell’Acqua, University Parking: Overnight parking fees for summer: $5.00 Ski Time Spare regulation of ER Ca2+ stores and other organelles; celebrating Bill of Colorado School of Medicine Parking, $10.00, self-parking in hotel Catterall and ion channels. Presentations in these sessions will be made James S. Trimmer, underground garage, $15.00 valet. by both new, up-and-coming investigators as well as established leaders University of California, Davis in the ion channel field, including several members of the National Academy of Sciences. Each session will also include two short-talks to be selected from the abstracts, with an emphasis on presentations by Register graduate students, postdoctoral trainees, and junior faculty. Now!

Lysophospholipid and Related Mediators – From Bench to Clinic August 20-25, New Orleans Marriott, New Orleans, LA

This is the leading international conference in lysophospholipid Highlights Important Deadlines biology, attracting participants from all continents. The focus this SRC ▶▶Keynote Address Early Bird Deadline: July 9, 2017 is on the physiological and pathophysiological roles of sphingosine “Emerging Roles of Last Day to Register: July 20, 2017 1-phosphate, lysophosphatidic acid and other lysophospholipids. New Lysophosphatidylserine in and established basic scientists, clinical researchers, academics, and Immune System” Transportation & industry partners are brought together to share expertise and foster ▶▶Career Development Workshop Lodging focused on early career collaboration, thereby accelerating the pace of scientific discovery Official Conference Lodging: and facilitating translation from early research to clinical practice. scientists New Orleans Marriott, 555 Canal Indeed, the development of Fingolimod, the first oral treatment for ▶▶Short talks will be selected Street, New Orleans, LA 70130 from submitted abstracts multiple sclerosis, is an excellent example of this, as first reported at this Airport Information: The closest conference in 2001. airport is Louis Armstrong New Keynote Speakers Orleans International Airport (MSY). The conference provides opportunities for substantive interactions Junken Aoki, AMED-CREST, The airport is approximately 25 between early-stage and established basic, translational and Japan minutes away from the Marriott. pharmaceutical investigators with an interest in lysophospholipid Julie Saba, UCSF Benioff Please reserve a shuttle beforehand or take a taxi. biology in health and disease. Presentations and posters (with several Children’s Hospital Oakland, CA Parking: Valet parking is available at prizes) will range from molecular aspects of lysophospholipid biology Conference Organizers the hotel for $45.30 per day, limited through to emerging therapeutics, genetic and disease models and to one car per guest room. molecular modelling. Late-breaking scientific advances and junior Susan Pyne, University of investigators will feature on the final program, which includes keynote Strathclyde lectures, the Journal of Lipid Research Lectureship and a careers Nigel J. Pyne, University of workshop for early career scientists. Strathclyde Register Now!

Register Now! www.faseb.org/SRC 11 2017 Science Research Conferences Mechanism and Regulation of Prokaryotic Transcription June 25 – 30, Saxtons River, VT – Vermont Academy

This SRC will focus on the process of transcription in prokaryotes, from Highlights Important Deadlines structure/function investigations to transcription networks and system ▶▶Keynote Address “Regulation of Early Bird Deadline: May 14, 2017 level regulation. In all organisms, controlling the process of transcription Bacterial Transcription” Last Day to Register: May 25, 2017 is fundamental to gene expression, gene regulation, and development. ▶▶Career Development Workshop RNA polymerase, which transcribes genomic DNA into RNA, is the ▶▶Lightning round for poster Transportation & complex protein machine that performs transcription. Additional factors presenters Lodging that alter initiation, elongation, or termination of transcription program Keynote Speakers Official Conference Lodging: an amazing variety of developmental pathways. Biochemical and Vermont Academy, 10 Long Sankar Adhya, National Cancer genetic investigations of transcription regulation have a long history Walk, Saxtons River, VT 05154 Institute of revealing the myriad ways that gene expression can be controlled. Airport Information: Vermont Joan Conaway, Stowers Attendees can expect exciting sessions on RNA polymerase structural Academy in Saxtons River, Institute for Medical Research Vermont is 130 miles from Logan biology, mechanisms that control initiation, elongation, and termination, International Airport (BOS) in Boston, regulation of transcription in pathogens, RNA-based control, Conference Organizers Massachusetts and 110 miles from Bradley International Airport (BDL) transcriptional networks, and connections between cell topology and National Deborah Hinton, near Hartford, Connecticut. gene expression. Institutes of Health Since its inception in 1991, the FASEB conference on Mechanism and Elizabeth Campbell, The Regulation of Prokaryotic Transcription has been held biannually at Rockefeller University Vermont Academy in Saxtons River, VT. It is now considered to be the Eduardo Groisman, Yale premier meeting in the field of prokaryotic transcription. We are very University proud of the fact that there is so much collegiality and a broad age Register range at this conference. Approximately half of the speakers are chosen Now! from submitted abstracts and the lively poster sessions are always well-attended by all participants. There will be many opportunities for participants to meet new friends and foster new collaborations.

Mechanisms in Plant Development July 30 – August 4, Saxtons River, VT – Vermont Academy

This SRC is an important and unique conference at the intersection of Highlights Important Deadlines plant development, signaling, cell biology, modeling and genomics. This ▶▶Prime international meeting on Early Bird Deadline: June 18, 2017 conference, which has been held every 2-3 years for the past 2 decades plant developmental biology Last Day to Register: June 29, is the only meeting entirely dedicated to plant development. Plant for more than two decades 2017 growth and development are at the core of agricultural productivity ▶▶Outstanding opportunities Transportation & and important for human survival. In addition, because plants evolved for students, post doctoral Lodging multicellularity independently from animals they provide insight into researchers, and early career faculty to discuss their research Official Conference Lodging: common and unique solutions to coordination of the behavior of cells Vermont Academy, 10 Long ▶▶Large number of abstracts and tissues. At this SRC, outstanding researchers from around the world Walk, Saxtons River, VT 05154 selected for short talks in present cutting edge research directed towards understanding how sessions throughout the Airport Information: Vermont different aspects of plant growth and development are controlled in conference Academy in Saxtons River, Vermont is 130 miles from Logan response to intrinsic and extrinsic cues and how those mechanisms ▶▶Great opportunity to learn more are conserved or modified over evolutionary time. The conference International Airport (BOS) in Boston, about the newest technologies Massachusetts and 110 miles from format includes invited speakers and speakers selected from submitted and interdisciplinary approaches Bradley International Airport (BDL) abstracts, lots of time for poster viewing and intensive scientific to address questions in near Hartford, Connecticut. discussions. Special sessions foster interactions between established developmental biology scientists and young investigators. The small size of the meeting as well Keynote Speakers as the secluded location enable discussions of new ideas and emerging concepts in the rapidly moving field of plant development. Philip Benfey, Duke University Conference Organizers Marja Timmermans, Register University of Tuebingen Now! Doris Wagner, University of Pennsylvania

12 FASEB Science Research Conferences 2017 Science Research Conferences 2017 Mitochondrial Biogenesis and Dynamics in Health, Disease and Aging May 21 – 26, West Palm Beach, FL – The Marriott West Palm Beach

The central role of mitochondria in normal cell physiology is evident Highlights Important Deadlines from human diseases, including metabolic disorders and aging, which ▶▶Collegial format with a unique Early Bird Deadline: April 20, 2017 are associated with changes in mitochondrial function. This SRC mixture of research into Last Day to Register: April 28, will facilitate an exchange of knowledge and promote collaborative basic molecular mechanisms 2017 interactions between investigators that study basic aspects of and applied, translational mitochondria with translational investigators engaged in studying investigations of human Transportation & diseases mitochondrial roles in human health, human diseases including age- Lodging Career Development Workshop associated disorders, and the aging process. It will gather basic and ▶▶ Official Conference Lodging: translational scientists with a broad range of research interests and Marriott West Palm Beach, 1001 Keynote Speaker Okeechobee Boulevard, West Palm different levels of experience ranging from established investigators to Jodi Nunnari, University of Beach, FL 33401 graduate students. A collegial format will facilitate discussions between California, Davis Airport Information: Palm Beach all participants with the goal of bringing together their unique insights International Airport (PBI) is less than and integrate them into this rapidly expanding field. Conference Organizers 3 miles from the Marriott West Palm The major topics covered include 1) mitochondrial gene expression; Carlos T. Moraes, University Beach. Fort Lauderdale airport (FLL) is one hour away. 2) respiratory chain complex assembly; 3) mitochondrial protein of Miami Parking: Self-parking is $4.00 per biogenesis and quality control; 4) mitochondrial stress in cell signaling Martin Ott, Stockholm day and aging; 5) mitochondrial dynamics in development and disease; 6) University mitochondrial dna-driven mechanisms of mitochondrial dysfunction; Eric A. Schon, Columbia 7) new pathways, biomarkers and technologies to study mitochondrial University function; 8) challenges and opportunities in mitochondrial biology and medicine. Through these topics, the most recent advances in the biology, dynamics and regulation of mitochondria will be discussed and linked with the pathophysiology of mitochondrial disorders and the Register aging process. Now!

Mobile DNA in Mammalian Genomes June 18 – 23, Big Sky, MT – Big Sky Resort

This SRC focuses on the dynamic nature of mobile DNAs in Highlights Important Deadlines mammalian genomes and their phenotypic impacts. Topics will ▶▶Career Development Workshop Early Bird: June 2, 2017 encompass mechanistic and evolutionary aspects of diverse types of for early career scientists Last Day to Register: June 17, retrotransposons, including LINE-1 and endogenous retroviruses, as ▶▶Meet-the-Experts sessions 2017 well as DNA transposons and related human genes. Attendees will also ▶▶Short talks selected from explore interactions between these sequences and the epigenome submitted abstracts Transportation & and endogenous machinery of DNA repair and rearrangement. These Lodging elements comprise are a major portion of our DNA, and are significant Conference Organizers Official Conference Lodging: contributors to genomic diversity in the form of structural variation. Geoff Faulkner, University of Huntley Lodge, Big Sky Resort, 50 Big Sky Resort Road, Big Sky, MT 59716 While the germ line is a well-known site of activity of mobile genetic Queensland elements, there is increasing evidence for expression and mobility in Cedric Feschotte, University of Airport Information: The closest Utah School of Medicine airport to the Big Sky area is the somatic cells and in human diseases, particularly cancers. This makes it Bozeman Yellowstone International an exciting time for the field. Moreover, new insights are being gained David Ray, Texas Tech Airport (BZN). The lodge is into roles of mobile elements in shaping gene regulatory networks in University approximately one hour from the normal cells. Finally, harnessing mobile genetics elements as tools for Jose Garcia-Perez, Genyo- airport. forward genetic screens or gene delivery has provided new capabilities University of Granada to change the genome. This is a long standing meeting, certain to be Kathleen Burns, Johns Hopkins thought provoking, animated, and collegial all at once. University School of Medicine Register Now!

Register Now! www.faseb.org/SRC 13 2017 Science Research Conferences Molecular Mechanisms of Immune Cell Development and Function July 30 – August 4, Snowmass, CO – Base Village Conference Center

This SRC focuses on molecular mechanisms underlying fundamental aspects Highlights Important Deadlines of immune cell biology. The immune system has become an increasingly ▶▶Keynote address Early Bird Deadline: June 18, 2017 important model system for understanding information processing by ▶▶Career Development Workshop Last Day to Register: June 29, signaling pathways, signal-dependent transcriptional regulation, control ▶▶Short talks selected from 2017 of genomic integrity and DNA repair, and principles of development from submitted abstracts stem cells. Results from deep analysis of the regulation of lymphocyte Transportation & development from hematopoietic stem cells link this field to a broad range of Keynote Speaker Lodging hematopoietic, oncological, and developmental mechanisms for which the Dan Littman, New York Official Conference Lodging: lymphocyte vantage point can be very illuminating. This SRC is distinctive in University Medical School Base Village Conference Center, 84 Carriage Way, Snowmass Village, CO its focus on the molecular biology underlying immune responses, including Conference Organizers 81615 genome-wide insights into regulatory function and dysfunction. It also brings Cornelis Murre, University of Airport Information: Snowmass together research on B, T, NK, and innate system immune cells so that shared Village is just ten miles from the California, San Diego and contrasting mechanisms can be illuminated, both in the mature effector Aspen-Pitkin County Airport (ASE), cells and in their developing precursors. Barbara Kee, University of and 220 miles west of the Denver Chicago International Airport (DEN) Sessions include (1) early lymphocyte progenitors, (2) mechanisms that Yale University underpin lymphocyte development, (3) transcriptional regulation of David Schatz, Medical School lymphocyte differentiation, (4) antigen receptor assembly, (5) molecular and physical mechanisms that promote lymphocyte cell fate, (6) b cell activation and neoplasia, (7) the regulation of the immune responses, 8) innate immunity and (9) molecular pathways in innate immunity. The meeting will also include two poster sessions and two workshops consisting of short presentations chosen from submitted abstracts. By highlighting common and contrasting uses of similar mechanisms, the meeting will reveal unexpected synergies Register between areas of molecular immunology that are traditionally considered Now! distinct. This SRC emphasizes mixing national and international experts with young scientists, including postdoctoral fellows and graduate students, among the presenters in an open atmosphere of scientific exchange.

Molecular Pathogenesis: Mechanisms of Infectious Disease July 9 – 14, Snowmass, CO – Base Village Conference Center

Since 1994, this biennial SRC has been devoted to exciting and groundbreaking Highlights Important Deadlines research on viral, bacterial, fungal, and protozoal pathogens. The combined ▶▶Career Development Workshop Early Bird Deadline: May 28, 2017 themes are particularly pertinent regardless of their taxonomic differences as ▶▶Meet-the-Experts sessions Last Day to Register: June 8, 2017 microbes confront similar barriers from the host innate and acquired immune ▶▶Short talks selected from Transportation & systems, thus indicating both similar and unique virulence strategies. submitted abstracts Lodging ▶▶Two poster sessions To promote multi-disciplinary interactions and collaborations, the sessions are Official Conference Lodging: organized by pathogenesis theme, and each includes scientists from a variety Keynote Speaker Base Village Conference Center, 84 of fields. This is the only long-standing specialized international conference Carriage Way, Snowmass Village, CO that regularly attracts virologists, bacteriologists, mycologists, parasitologists, Mark Heise, The University of 81615 North Carolina at Chapel Hill immunologists, antimicrobial researchers, and translational scientists. Notable Airport Information: Snowmass Village is just ten miles from the speakers include Gordon Dougan, Kim Orth, Vern Carruthers, Erica Ollman Conference Organizers Saphire, Gerry Wright, Vanessa Sperandio, Russell Vance, and many others. By Aspen-Pitkin County Airport (ASE), The University of and 220 miles west of the Denver convening leading scientists with expertise in all areas of infectious disease, Erin Gaynor, British Columbia International Airport (DEN) this SRC optimizes information transfer, catalyzes provocative discussions, and fosters long-term cross disciplinary collaborations. The 2017 program will Michael Lorenz, University of include sessions on diverse aspects of host-microbe interactions from molecular, Texas McGovern Medical School evolutionary, immunological, and therapeutic perspectives. Talks will also include state-of-the-art approaches as well as how to adapt traditional approaches to meet today’s challenges. Finally, the relatively small meeting size, the diversity of fields, and structured and informal interaction opportunities – including three Register poster sessions, a formal career development session the final morning of the conference, free time in the afternoon, and Meet the Experts sessions – make Now! this an ideal meeting for young scientists to meet established investigators to develop networks of support that will foster career development.

14 FASEB Science Research Conferences 2017 Science Research Conferences 2017 Molecular, Physiological and Therapeutic Studies of Intestinal Lipid Transport and Metabolism July 23 – 28, Snowmass, CO – Base Village Conference Center

Intestinal lipid transport and metabolism is of high interest as Highlights Important Deadlines deregulation of these pathways can directly contribute to several ▶▶Keynote Address: Mansbach Early Bird Deadline: June 11, 2017 pathologies such as obesity, cardiovascular disease, and diabetes. Lecture Last Day to Register: June 22, Intestinal lipid transport and metabolism remains one of the most ▶▶Career Development Workshop 2017 dynamic areas in biomedical sciences, for both basic scientific inquiry ▶▶Short talks selected from and translational research. It reaches across the pathogenesis and submitted abstracts Transportation & treatment of major chronic diseases and includes leading-edge Lodging scientific technologies in human genomics, proteomics, lipidomics, Conference Organizers Official Conference Lodging: bioinformatics, systems biology, and new biological model systems. M. Mahmood Hussain, Base Village Conference Center, 84 Carriage Way, Snowmass Village, CO The 2017 SRC will present new knowledge that can ultimately be Winthrop University Hospital 81615 translated into clinical benefit for millions of patients not adequately Kimberly Buhman, Purdue University Airport Information: Snowmass addressed by existing therapeutic strategies. It will provide a unique Village is just ten miles from the forum for scientists at all levels to enrich their knowledge base, network, Gary Lewis, University of Aspen-Pitkin County Airport (ASE), and encourage new collaborations and new ideas, thus moving Toronto and 220 miles west of the Denver forward the field of lipid sciences. Major conference themes include International Airport (DEN) lipid transfer proteins, systemic metabolism of intestinal lipoproteins, cholesterol metabolism, lipid droplets formation and mobilization, integrative physiological studies of lipids and lipoproteins, intestinal lipid metabolism in other organisms, chylomicron assembly, and enzymes in intestinal lipid synthesis. This SRC provides an international forum of cutting-edge research by graduate students, postdoctoral fellows, Register and established scientists. A large number of oral presentations will be Now! selected from the abstracts, and the selected talks, poster presentations, and recreational activities will provide students and postdoctoral fellows opportunities to exchange ideas and formulate new collaborations.

A Multidisciplinary Approach to Addressing Health Disparities and Inequities in the United States: Cardiovascular Diseases NEW! July 23 – 28, Scottsdale, AZ – Scottsdale Plaza Resort

This SRC will focus on improving our understanding of the scientific, Highlights Important Deadlines socioeconomic, clinical, and health policy basis of disparities ▶▶Keynote address: “Historical Early Bird Deadline: June 11, 2017 in cardiovascular health outcomes in the United States, with a Perspective on Health Last Day to Register: June 22, 2017 view to addressing the challenges posed at every level including Disparities/Inequities in complementary and integrative health. Although life expectancy in Cardiovascular Diseases in the Transportation & the United States has increased significantly over the past five decades, U.S.” Lodging Meet-the-Experts sessions key indicators of health outcomes vary markedly by race, ethnicity, sex, ▶▶ Official Conference Lodging: socioeconomic status, and geographic location. Cardiovascular disease ▶▶A Biomedical Research Scottsdale Plaza Resort, 7200 North accounts for more deaths in black and Latino adults than cancer, HIV, Workforce Development Scottsdale Road, Scottsdale, AZ 85253 Workshop and homicide, together. According to the 2013 CDC Health Disparities Airport Information: The and Inequalities Report, non-Hispanic black adults are at least 50 closest airport is the Sky Harbor Keynote Speakers International Airport (PHX) in percent more likely than their non-Hispanic white counterparts to die To be announced Phoenix. The airport is approximately prematurely of heart disease or stroke. As a result, health disparities in 30 minutes away. The Scottsdale cardiovascular disease has become an important focus for Congress Conference Organizers Plaza Resort offers an airport shuttle that runs daily from 5am until 9pm, and the federal government. To draw attention to this issue, this SRC will Sunny E. Ohia, College of focus on building a multi-disciplinary approach to addressing health every 30 minutes. The cost is $23 per Pharmacy and Health Sciences, person each way. disparities and inequities in the United States. This SRC provides an Texas Southern University opportunity for multi-disciplinary teams to develop a roadmap for future Adebayo Oyekan, College of discussions on solutions to health disparities/inequities in cardiovascular Pharmacy and Health Sciences, diseases in the United States. The target audience includes clinicians, Texas Southern University Register health policy makers, epidemiologists, researchers, health educators, trainees at junior faculty, postdoctoral fellows, and graduate students. Now! The conference will include oral, poster, and meet-the-expert sessions and a biomedical research workforce development workshop.

Register Now! www.faseb.org/SRC 15 2017 Science Research Conferences NAD+ Metabolism and Signaling July 9 – 14, New Orleans, LA – New Orleans Marriott

NAD and its metabolites are important regulators of cancer, Highlights Important Deadlines metabolic disease, autoimmunity, and aging. They play important ▶▶Meet-the-Experts sessions Early Bird Deadline: May 28, 2017 roles in energy metabolism, function as signaling molecules, and ▶▶Short talks selected from Last Day to Register: June 8, 2017 as protein modifications such as ADP-ribosylation. This diversity of submitted abstracts Transportation & function demonstrates the biological importance of NAD and the ▶▶Career Development Workshop interconnectivity between cellular metabolism, physiology, and Lodging cellular signaling. Recently, significant progress has been made in our Keynote Speaker Official Conference Lodging: New Orleans Marriott, 555 Canal Vilhelm A. Bohr, NIH understanding of NAD that highlight its broad relevance to human Street, New Orleans, LA 70130 health and disease. This meeting brings together all of the leading Conference Organizers Airport Information: The closest experts in NAD biology to one venue with the goal of advancing our airport is Louis Armstrong New understanding of the molecule. Experts come from several NAD relevant Paul Chang, Ribon Orleans International Airport (MSY). fields that include Poly-(ADP-ribose) polymerases (PARPs), Sirtuins, NAD Therapeutics The airport is approximately 25 dependent signaling networks, calcium signaling, NAD biosynthesis and Charles Brenner, University minutes away from the Marriott. of Iowa Please reserve a shuttle beforehand the chemical biology of NAD. or take a taxi. Lenny Guarente, MIT More than 30 scientific leaders from institutions worldwide will present Parking: Valet parking is available at their latest data. In addition, a large number of oral presentations will be Anne-Laure Perraud, the hotel for $45.30 per day, limited selected from submitted abstracts. Selected talks, poster presentations, University of Colorado, Denver to one car per guest room. and recreational activities will provide students and postdoctoral fellows Mathias Ziegler, University opportunities to exchange ideas and interact with senior colleagues. of Bergen Register For the first time, this meeting will be held in the exciting city of New Now! Orleans, an ideal setting to discuss science.

Origins and Benefits of Biologically Active Components in Human Milk July 16 – 21, Lisbon, Portugal – Marriott Lisbon

Breastfeeding is the normative standard for infant nutrition, and clinical Highlights Important Deadlines and epidemiological data support clear health benefits for the mother and ▶▶Career Development Workshop Early Bird Deadline: May 28, 2017 infant. Public policies have focused on improving rates of breastfeeding ▶▶Meet-the-Experts Session Last Day to Register: June 15, globally; however, our understanding of the molecular, chemical, ▶▶Poster awards and Travel 2017 and cellular composition of human milk and its effect on the infant is Grants available for trainees incomplete. Milk contains more than 700 potentially bioactive constituents Transportation & comprised of carbohydrates (lactose and human milk oligosaccharides- Keynote Speakers Lodging HMO), proteins, lipids, vitamins, minerals, and others. Technological Lawrence Grummer-Strawn, Official Conference Lodging: advancements have made it possible to study many of these milk World Health Organization, Geneva Lisbon Marriott Hotel, Avenida dos Combatentes, Lisboa (Lisbon) bioactives. This SRC is the second on this topic and the first outside of the Conference Organizers Portugal 1600-042 1600-042 U.S. The 2015 program focused on HMO and microbiota. The 2017 program Sharon Donovan, University Airport Information: The will additionally include bioactive proteins and lipids, with an emphasis on closest airport is the Lisbon of Illinois, Urbana-Champaign their effects on cognitive and immune outcomes to the neonate. Sessions Portela Airport (LIS), which is 4.3 will address the interplay between maternal and environmental factors Ted Barrett, Lovelace miles or 6.9 kilometers from the that influence nutrient delivery to the infant pre- and postnatally, as well as Respiratory Research Institute Lisbon Marriott Hotel. developmental programming of infant outcomes during the first 1000 days Kal Ramanujam, Arla Foods Parking: €19 EUR per day. of life. The conference is specifically designed to foster interactions among Ingredients established and emerging investigators from all sectors. It will bring together more than 30 invited speakers from across the globe with broad ranges of expertise to share their latest research findings. The keynote lecture will set the stage by reviewing the most recent epidemiological evidence for the health benefits of breastfeeding and current research gaps. Register Now!

16 FASEB Science Research Conferences 2017 Science Research Conferences 2017 Polycystic Kidney Disease: Challenges, Differing Viewpoints and Ways Forward June 25 – 30, Big Sky, MT – Big Sky Resort

This SRC focuses on the autosomal dominant (ADPKD) and recessive Highlights Important Deadlines (ARPKD) forms of PKD, autosomal dominant polycystic liver diseases with ▶▶Keynote Address “Strategies Early Bird Deadline: May 14, 2017 mild or no kidney involvement (ADPLD) and syndromic forms of PKD for Kidney Regeneration” Last Day to Register: May 25, 2017 caused by mutations in genes encoding for proteins in the primary cilium ▶▶Special Lecture: Regulatory (ciliopathies). It will bring together investigators from a wide range of Path to Drug Approval for Transportation & different research areas sharing an interest on this topic. The conference Inherited Slowly Progressive Lodging Renal Diseases seeks to 1) to assemble an interdisciplinary program of basic scientists Official Conference Lodging: and clinical researchers at the forefront of PKD research to provide a ▶▶Career Development Huntley Lodge, Big Sky Resort, 50 Big comprehensive update on recent advances in PKD; 2) to provide a format Workshop Sky Resort Road, Big Sky, MT 59716 Airport Information: The closest where trainees and junior investigators can present, discuss and learn, Keynote Speaker with the goal of exciting them about PKD and inspiring them to become airport to the Big Sky area is the Juan Carlos Izpisua- Bozeman Yellowstone International the next generation of PKD researchers; 3) to generate discussion to Belmonte, Salk Institute for Airport (BZN). The lodge is help resolve unanswered questions in PKD and promote collaboration; Biologic Studies approximately one hour from the and 4) to promote the development of novel therapies for PKD by airport. juxtaposing basic scientists, clinical investigators, and representations of Conference the pharmaceutical industry. Eight of the oral presentation sessions are Organizers structured around a theme: 1) Genetic mechanisms; 2) Cell biology of PKD Vicente Torres, MD, PhD, proteins, extracellular vesicles and cilia; 3) Epigenetics and microRNAs; 4) Mayo Clinic Register Cilia, calcium, and cAMP signaling; 5) Other pathways and model systems; Marie Trudel, PhD, 6) Disease mechanisms in other tissues and organs; 7) Cell metabolism University of Montreal Now! and metabolomics; 8) Biomarkers and clinical trials. A ninth session is reserved for late breaking abstracts.

Protein Aggregation in Health and Disease June 11 – 16, Big Sky, MT – The Steamboat Grand Hotel

This SRC brings together scientists working on biophysical and biological Highlights Important Deadlines aspects of protein aggregation and connect physical understand ▶▶Career Development Panel Early Bird Deadline: May 3, 2017 of aggregation to its biological consequences in post mitotic cells. featuring academic and Last Day to Register: May 11, 2017 The conference will begin with keynote talks by two leading figures, industry leaders, presenting Dr. Virginia Lee and Dr. Sheena Radford. Their talks will highlight their thoughts in a Town Hall Transportation & the translational aspects and biophysical underpinnings of protein format. Lodging Short talks selected from aggregation. ▶▶ Official Conference Lodging: The submitted abstracts Steamboat Grand Resort, 2300 Mt The remainder of the conference will be organized around specific ▶▶Meet-the-Experts Session Werner Cir, Steamboat Springs, CO thematic sessions that focus on specific proteins or collections of 80487. proteins and work up to uncovering the impact of protein aggregation Keynote Speaker Airport Information: The on cellular processes and disease states. This conference will span a Virginia Lee, University of Steamboat Grand Resort is 22 miles range of topics. These include a discussion of emerging technologies Pennsylvania from the Steamboat-Yampa Valley to study protein aggregation in vitro and in cells, advancements in our Sheena Radford, University of Regional/Hayden Airport (HDN) understanding of cellular stresses induced by protein aggregation, our Leeds and 155 miles northwest of Denver International Airport (DIA). ability to target the stress response pathways therapeutically as a route Conference Organizers Parking: Overnight parking fees to finding cures for devastating neurological and systemic diseases, for summer: $5.00 Ski Time Spare routes that connect aggregation mechanisms and specific aggregates Rohit V. Pappu, Washington Parking, $10.00, self-parking in hotel to disease, methods to target aggregation or particular species in order University in St. Louis underground garage, $15.00 valet. to cure disease, the emerging synergy between protein aggregation Christina Sigurdson, and phase separation in the context of form liquid-like membraneless University of California San Diego bodies within cells, and the functional role of protein aggregates, a theme that continues to be paradigm shifting in biology. Taken together these sessions will give the participants an integrative view of protein aggregation and the impact it has on health and disease. Register The cross-disciplinary nature of the conference is accentuated by the Now! program, which brings together biophysicists, structural biologists, and bioengineers with cell biologists and clinical scientists.

Register Now! www.faseb.org/SRC 17 2017 Science Research Conferences Protein Kinases and Protein Phosphorylation August 6-11, Robinson College, Cambridge, UK

This SRC focuses on the biology of protein kinases and phosphorylation Highlights Important Deadlines signaling. Among FASEB’s longest-running SRCs, it brings together ▶▶Career Development Workshop Early Bird Deadline: June 18, 2017 a dynamic international community of junior investigators, trainees, ▶▶Meet-the-Experts sessions Last Day to Register: July 6, 2017 and established researchers from a field that is achieving startling new ▶▶Short talks selected from insight and medical breakthroughs. The program will link detailed submitted abstracts Transportation & understanding of protein structure and biochemical mechanism Lodging to control of large-scale processes like the cell division cycle, cell Keynote Speaker Official Conference Lodging: morphogenesis, and metabolism. Tony Hunter, American Cancer Robinson College, Cambridge, Society Professor, Salk Institute Grange Road, Cambridge CB3 9AN, This SRC will explore the field’s latest research, which is revealing for Biological Studies United Kingdom surprising mechanisms of regulation, previously unappreciated Airport Information: Stansted subcellular organization, logic of pathways that coordinate diverse Conference Organizers Airport is approximately 40 minutes intracellular systems. Importantly, derangement of kinase signaling Kathryn Ferguson, by road from Cambridge and underlies disease, including cancer and diabetes. Drugs targeting Department of Pharmacology, Gatwick and Heathrow Airports are kinases and phosphorylation have achieved dramatic cures and promise Yale University School of about 1.5 - 2 hours by road from the College. more, and the conference has consistently offered a robust platform for Medicine clinically important work. To foster international scientific connections Eric Weiss, Department the 2017 conference will be held at Cambridge University, a world-class of Molecular Biosciences, academic research hub with outstanding facilities, recreational options, Northwestern University and social venues. Platform and poster sessions will feature insights from structural and biochemical analysis, as well as emerging research in the control of cell division, metabolism, and cell architecture. The meeting will bring together scientists using a wide range of approaches, from structural biology and biochemistry to proteomics, systems biology, and cell biology. In addition to the conference’s traditionally deeply ingrained Register focus on developing treatments for important human maladies, half Now! of the platform sessions will have an explicit tie to clinical issues: malignancy, cancer, immunity and inflammation, and metabolic disease.

Protein Lipidation: Enzymology, Signaling and Therapeutics July 16 – 21, Saxtons River, VT – Vermont Academy

This SRC will focus on biochemical, structural, and cellular mechanisms Highlights Important Deadlines of fatty acylation, prenylation, and post-prenylation processing of ▶▶“Research Snapshot” elevator Early Bird Deadline: June 4, 2017 proteins, emerging therapeutics, the transport of intracellular lipids, pitch presentations from Last Day to Register: June 15, and the importance of protein-lipid interactions for cellular signaling graduate students and 2017 at specialized membrane domains and its relevance in disease. This postdoctoral fellows conference is the only international venue where these broad but ▶▶Career Development Workshop Transportation & Meet-the-Experts Sessions closely interrelated topics are discussed at length. As the field of protein ▶▶ Lodging lipidation has grown over the past 10 years, it has become highly Keynote Speaker Official Conference Lodging: interdisciplinary. This this meeting allows scientists and biomedical Gisou Van der Goot, École Vermont Academy, 10 Long Walk, Saxtons River, VT 05154 researchers from diverse disciplines to come together, discuss new ideas, Polytechnique Fédérale de and form synergistic collaborations. Lausanne Airport Information: Vermont Academy in Saxtons River, Presentations will highlight progress in our understanding of how Youla Tsantrisoz, McGill Vermont is 130 miles from Logan lipid-modified proteins promote normal physiological processes, with University International Airport (BOS) in Boston, emphasis on their important roles in major human disorders. Topics Massachusetts and 110 miles from Conference Organizers Bradley International Airport (BDL) will also include emerging drug discovery and development efforts. A near Hartford, Connecticut. significant number of submitted abstracts will be selected for short talks, Rami Hannoush, Genentech and awards will be given to the top scientific posters. Research snapshop Luke Chamberlain, elevator pitch presentations from graduate students and postdoctoral University of Strathclyde fellows, a specific Meet-the-Experts session and social activities will allow Patrick Casey, Duke Register students and postdoctoral researchers to interact with invited speakers, University School of Medicine Now! including industry speakers working in drug discovery, and to form Anant Menon, Weill Cornell potential new scientific collaborations. Medical College

18 FASEB Science Research Conferences 2017 Science Research Conferences 2017 Rapid Signaling and Genomic Steroid Hormone Actions in Health and Disease June 11 – 16, Snowmass, CO – Base Village Conference Center

Steroid hormone action impacts many aspects of physiology and Highlights Important Deadlines disease states. Although scientists in the field traditionally focused on ▶▶Keynote Address “Circadian Early Bird Deadline: May 3, 2017 how nuclear steroid receptors mediate gene transcription, it is now Metabolism in the Light of Last Day to Register: May 11, 2017 established that these same receptors exist and function at various Evolution” cellular locations including the cell membrane and mitochondria. ▶▶New format: Senior scientist Transportation & Thus, this conference focuses on the latest advances and approaches panel discussions following Lodging each short talk to understand how signaling from extra-nuclear and nuclear steroid Official Conference Lodging: ▶▶Career Development Workshop receptors integrate to produce genomic and non-genomic biological Base Village Conference Center, 84 effects. The 2017 conference centers on steroid hormone action in Keynote Speaker Carriage Way, Snowmass Village, CO 81615 cancer, metabolism, neuroscience, cardiovascular effects, ion channels, Mitchell Lazar, University of and lung disease. It will feature many new speakers and provide Airport Information: Snowmass Pennsylvania School of Medicine Village is just ten miles from the the opportunity for trainees to present their work in oral and poster Liam Holt, New York Aspen-Pitkin County Airport (ASE), sessions. Most importantly, many productive collaborations between University and 220 miles west of the Denver scientists, junior and senior, have occurred from the interactions during International Airport (DEN) this meeting. Junior scientists and trainees are especially encouraged Conference Organizers to interact with senior faculty, in multiple venues that encourage this Carol A. Lange, University of during the meeting. Travel funds for trainees are also a priority of this Minnesota School of Medicine meeting. Ellis Levin, University of California, Irvine, School of Medicine Don DeFranco, University Of Pittsburgh School of Medicine Stephen Hammes, University of Rochester School of Register Medicine Now!

Regulation and Function of Small GTPases June 11 – 16, West Palm Beach, FL – Marriott West Palm Beach

This SRC provides an interactive forum that covers the latest Highlights Important Deadlines developments in the small GTPase field and presents the newest ▶▶Short talks selected from Early Bird Deadline: May 3, 2017 technological advancements that are being used to unravel the complex submitted abstracts Last Day to Register: May 11, 2017 roles of small GTPases in human health and disease. Small GTPases (e.g., ▶▶“Meet-the-Expert” session Ras, Rac, Rho, Cdc42, Rab, Rap, Rheb, and Ral) are essential for key cellular ▶▶Career-Oriented workshops Transportation & processes such as cell differentiation, proliferation, and migration, as well for trainees and early-career Lodging investigators as the regulation of subcellular events such as vesicle trafficking. These Official Conference Lodging: critical functions of small GTPases make them important participants Keynote Speaker Marriott West Palm Beach, 1001 in a wide variety of physiological and pathophysiological processes. Allan Balmain, University of Okeechobee Boulevard, West Palm Beach, FL 33401 The founding member of the small GTPase superfamily, Ras, is the California San Francisco Helen most commonly mutated oncogene in human cancers, and many Diller Family Comprehensive Airport Information: Palm Beach International Airport (PBI) is less than Cancer Center other small GTPases (including RhoA, Rac1, Rab5, Rheb, and RalA) also 3 miles from the Marriott West Palm play fundamental roles in cancer development and progression. In Conference Organizers Beach. Fort Lauderdale airport (FLL) addition to a strong cancer theme, this SRC will also focus on other is one hour away. Medical biomedically important events, including the promotion of vascular Carol Williams, Parking: Self-parking is $4.00 per diseases, immunological abnormalities, mental disorders, and metabolic College of Wisconsin, Milwaukee day. Cancer conditions. For these reasons, progress from a number of fields in Angeliki Malliri, Research UK Manchester addition to cancer biology will be highlighted, including neurobiology, Institute developmental biology, computational biology, and membrane biophysics. The meeting seeks to stimulate the cross-pollination of Register ideas among researchers investigating basic biochemical mechanisms, Now! cell and tissue biology, and translational models to define the diverse functions of small GTPases.

Register Now! www.faseb.org/SRC 19 2017 Science Research Conferences Reversible Acetylation in Health and Disease August 6 – 11, Big Sky, MT – Big Sky Resort

Over the past few years, the “epigenetic” regulation of the genome has Highlights Important Deadlines become increasingly important to understanding both the etiology ▶▶Keynote Address “Mechanisms Early Bird Deadline: June 25, 2017 and fundamental mechanisms of aging and age-related diseases. Key Involved In Cooperative Last Day to Register: July 6, 2017 to epigenetic regulation are two classes of lysine-modifying enzymes, Functions Of Histone the histone deacetylases (sirtuins and HDACs) and the histone Acetyltransferases” Transportation & acetyltransferases (HATs). ▶▶Panel discussion: Terry Lodging Sheppard (Nat. Chem. Biol. This SRC is the only conference dedicated to protein acetylation, and will Editor), Philip Cole, James Ellis Official Conference Lodging: Huntley Lodge, Big Sky Resort, 50 Big (GSK), Lisa Monteggia “Career bring together leaders in the field to exchange exciting new fundamental Sky Resort Road, Big Sky, MT 59716 discoveries such as new lysine post-translational modifications (e.g. Choices” ▶▶Meet- the-Experts sessions Airport Information: The closest 3-hydroxybutyryl lysine and palmitoyl lysine) and the how these airport to the Big Sky area is the modifications can regulate transcription, cell signaling, and protein Keynote Speakers Bozeman Yellowstone International secretion. Robert Roeder, The Rockefeller Airport (BZN). The lodge is approximately one hour from the University A primary objective of the conference is to transfer knowledge and foster airport. collaboration between basic academic researchers, clinical scientists, David Sinclair, Harvard and industrial researchers to understand how lysine acetylation controls University human health and how to prevent and treat a diverse set of age- Conference Organizers related diseases that could extend human healthspan and lifespan. A second objective is to foster the development and interests of younger Li-Huei Tsai, Massachusetts investigators to help support their career development. This meeting Institute of Technology Hening Lin, Cornell University is particularly timely because recent development on bromodomain and HHMI inhibitors is continuing to generate a lot of interests and more clinical data Yingming Zhao, The on small molecule modulators of sirtuins and HDACs are being generated. Register University of Chicago Now!

Signal Transduction in the Immune System June 18 – 23, Snowmass, CO – Base Village Conference Center

This SRC focuses on the most recent advances in the fields of signal Highlights Important Deadlines transduction in the immune system, with an emphasis on the ▶▶Career Development Workshop Early Bird Deadline: May 7, 2017 coupling of signaling to differentiation pathways, the development ▶▶Meet-the-Experts sessions Last Day to Register: May 18, 2017 of new technologies for understanding and imaging signaling, ▶▶Short talks selected from interactions between metabolism and lymphocyte activation and submitted abstracts Transportation & differentiation, signaling through mechanotransduction, and signaling Keynote Speaker Lodging through immunomodulatory receptors in cancer. These topics have Doreen Cantrell, University of Official Conference Lodging: direct relevance to a number of clinically important areas, including Dundee Base Village Conference Center, 84 autoimmunity, immunodeficiency diseases, transplantation immunology, Carriage Way, Snowmass Village, CO 81615 tumor immunology, infectious diseases and chronic inflammation. In Conference Organizers particular, leukocyte metabolism, the mechanism and feedback of antigen Airport Information: Snowmass Daniel D. Billadeau, Mayo Village is just ten miles from the receptor signaling initiation and kinase regulation, immunomodulatory Clinic Aspen-Pitkin County Airport (ASE), receptors, and cytoskeletal changes that accompany leukocyte activation Art Weiss, University of and 220 miles west of the Denver and migration have provided a wealth of new information that will California, San Francisco International Airport (DEN) enhance our understanding of the complex pathways that control Janis K. Burkhardt, immune responses under normal as well as pathogenic situations. As University of Pennsylvania such, the mechanisms and pathways that will be discussed in detail at this Morgan Huse, Memorial conference represent a major source of target leads for the development Sloan Kettering Cancer Center of new therapeutics to treat immunological disorders and sit at the forefront and intersection of basic and translational research. There will also be sessions that bridge these two types of research. The 2017 Register meeting is the 9th on the series and features speakers from around the Now! world who will discuss cutting-edge research in the area of immune cell signaling.

20 FASEB Science Research Conferences 2017 Science Research Conferences 2017 TGF-ß Superfamily: Signaling in Development and Disease July 9 – 14, Lisbon, Portugal – Marriott Lisbon

This SRC is an important and unique scientific conference where the Highlights Important Deadlines pivotal role of TGF-β family members, including TGF-βs, nodal, activins, ▶▶Keynote Lecture Early Bird Deadline: May 21, 2017 BMPs, and GDFs, in developmental, homeostatic, and pathological “Developmental syndromes Last Day to Register: June 8, 2017 processes is explored through formal talks, poster sessions, and interactive and genetic alterations in the and intensive scientific discussion sessions. This field is expanding into TGF-β pathway” Transportation & previously uncharted areas of biology and human pathogenesis. Program ▶▶Career Development Workshop Lodging topics include tissue morphogenesis in development and disease, ▶▶Meet-the-Experts sessions Official Conference Lodging: signaling networks and crosstalk, inflammation, vasculature and tissue Lisbon Marriott Hotel, Avenida transformation, tissue microenvironment dynamics in disease, therapeutic Keynote Speaker dos Combatentes, Lisboa (Lisbon) Portugal 1600-042 frontiers of TGF-β signaling, and homeostatic and metabolic control of Harry C. Dietz, Institute of growth and disease. Genetic Medicine, Investigator, Airport Information: The Howard Hughes Medical Institute, closest airport is the Lisbon Portela Airport (LIS), which is 4.3 This meeting includes researchers from around the world presenting Director, Smilow Center for diverse, cutting edge and forward looking research directed towards miles or 6.9 kilometers from the Marfan Syndrome Research , Lisbon Marriott Hotel. a fundamental understanding of the mechanisms of TGF-β family Johns Hopkins University School Parking: €19 EUR per day signaling: how these factors mediate context- and temporal- of Medicine specific signals to orchestrate complex developmental processes, how aberrations in this signaling pathway lead to developmental Conference Organizers abnormalities and human disease pathologies, and how this knowledge Akiko Hata, Cardiovascular may come to be applied in the clinic. All lectures will be held in an Research Institute, University of intimate setting with a limited number of participants that is an ideal California, San Francisco setting especially for young students and trainees and those who Mary Mullins, University of recently entered the TGF-β world to engage into a discussion with Pennsylvania Perelman School world-renowned experts. Speakers are encouraged to present and of Medicine discuss unpublished data. This meeting brings together a diverse group Register of cell biologists, developmental biologist, embryologist, biochemists, Now! physiologists, biophysicists, and translational biologists to share the latest developments in different fields.

Register Now! www.faseb.org/SRC 21 www.faseb.org/SRC

Coming Up in 2018! As of 2/14/17, subject to change

Biological Methylation: Fundamental Mechanisms in Human The Hilton Florence Metropole, Florence, Italy June 17 – 22 Health and Disease Calcium and Cell Function Granlibbaken Tahoe, Tahoe City, CA June 10 – 15 Cell Signaling in Cancer: From Mechanisms to Therapy The Steamboat Grand, Steamboat Springs, CO June 3 – 8 COAST 2018 The Plaza Scottsdale Resort, Scottsdale, AZ September 12 – 16 Cross Translational Research in Fibrosis Across Organs The Plaza Scottsdale Resort, Scottsdale, AZ September 30 – October 5 Dynamic DNA Structures in Biology St. Bonaventure University, Olean, NY July 15 – 20 Folic Acid, Vitamin B12 and One-Carbon Metabolism The Atlantica, Oak Island Resort & Conference July 29 – August 3 Center Functional Disulfide Bonds in Health and Disease The National Conference Center, Leesburg, VA June 17 – 22 Fundamental Biology and Pathophysiology of the Liver The Plaza Scottsdale Resort, Scottsdale, AZ June 10 – 15 Genome Engineering: Cutting-Edge Research and Applications The Hilton Florence Metropole, Florence, Italy June 24 – 29 Immunological Aspects of Metabolic Syndrome Base Village Conference Center, Snowmass, CO August 12 – 17 Immunoreceptors and Immunotherapy Base Village Conference Center, Snowmass, CO June 10 – 15 Lipid Droplets on the Move from Health and Disease The Steamboat Grand, Steamboat Springs, CO June 24 – 29 Machines on Genes Base Village Conference Center, Snowmass, CO June 24 – 29 Microbial Glycobiology The Plaza Scottsdale Resort, Scottsdale, AZ June 17 – 22 Molecular Biophysics of Membranes St. Bonaventure University, Olean, NY June 17 – 22 Nutrient Sensing and Metabolic Signaling Base Village Conference Center, Snowmass, CO August 5 – 10 Nutritional Immunology and the Microbiota: Rules of The National Conference Center, Leesburg, VA June 24 – 29 Engagement in Health and Disease Phospholipids: Dynamic Lipid Signaling in Health and Disease The Steamboat Grand, Steamboat Springs, CO July 29 – August 3 Post Transcriptional Control of Gene Expression: Mechanisms The Plaza Scottsdale Resort, Scottsdale, AZ June 24 – 29 of RNA Decay Protein Folding in the Cell St. Bonaventure University, Olean, NY July 22 – 27 Protein Phosphatases Base Village Conference Center, Snowmass, CO July 15 – 20 Protein Phosphorylation Networks in Health and Disease Base Village Conference Center, Snowmass, CO July 22 – 27 Retinal Neurobiology and Visual Processing St. Bonaventure University, Olean, NY June 24 – 29 Skeletal Muscle Satellite Cells and Regeneration The Steamboat Grand, Steamboat Springs, CO July 8 – 13 Small GTPases in Membrane processes: Trafficking, Autophagy, The National Conference Center, Leesburg, VA September 23 – 28 and Disease The 4th International Conference on Retinoids The Steamboat Grand, Steamboat Springs, CO June 10 – 15 The Lung Epithelium in Health and Disease The National Conference Center, Leesburg, VA July 29 – August 3 Trace Elements in Biology and Medicine Granlibbaken Tahoe, Tahoe City, CA June 3 – 8 Transcription, Chromatin and Epigenetics The Hilton Florence Metropole, Florence, Italy September 16 – 21 Translational Neuroimmunology Base Village Conference Center, Snowmass, CO July 8 – 13 Ubiquitin and Cellular Regulation Base Village Conference Center, Snowmass, CO June 17 – 22 Virus Structure and Assembly The Steamboat Grand, Steamboat Springs, CO July 22 – 27 Yeast Chromosome Biology and Cell Cycle The Steamboat Grand, Steamboat Springs, CO July 15 – 22

22 FASEB Science Research Conferences 2017 Science Research Conferences 2017 www.faseb.org/SRC e•Engag Organize! or e•C Thank you! pl o x n Do you have a passion for your scientific t E r PLATINUM LEVEL • i n b field? r u $10,000 or more a

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Organize a FASEB SRC. Organizing meetings is a e e

L ▶▶Option to display a table-top exhibit at the community responsibility. It fosters team building and w sponsored conference provides a valuable learning experience. If you are c w r ▶▶One (1) complimentary single occupancy a science professional holding an advanced medical w s / registration or doctoral degree and are active in scientific research, .f g a s e . or ▶▶Company logo in the program you may submit a proposal to organize a conference with b Logo and link to your company on the FASEB. ▶▶ FASEB SRC web page Learn. FASEB SRCs provide ample networking opportunities for both seasoned ▶▶Distribution of company brochure at the scientists and junior investigators, as attendees are encouraged to present posters sponsored conference and short talks, eat meals together, and converse with leaders in the field during Meet-the-Expert Sessions. GOLD LEVEL $5,000 - $9,999 Explore. To submit a proposal, please email [email protected] to request an application. Write “Proposal Application” and the year of the proposed conference ▶▶One (1) complimentary single occupancy in the subject line of the email. FASEB is currently accepting 2019 conference registration proposals until Monday, September 26, 2017. For more information, ▶▶Company logo in the program visit www.faseb.org/src. ▶▶Logo and link to your company on the FASEB SRC web page Engage. FASEB SRCs encourage dialogue among prominent scientists, faculty, post- Distribution of company brochure at the doctoral fellows and graduate students who are working in areas experiencing rapid ▶▶ sponsored conference scientific advances and conducting cutting-edge research. Meetings are traditionally small, averaging between 100 and150 participants, and held over five days. SILVER LEVEL $2,000 - $4,999 Contribute. FASEB SRCs are organized by leading investigators in their fields of expertise. ▶▶Company logo in the program ▶▶Logo and link to your company on the FASEB SRC web page ▶▶Distribution of company brochure at the Current Sponsors 2017 sponsored conference PLATINUM Pfizer, Inc. Research and Diagnostic BRONZE LEVEL Biolegend Pliant Therapeutics, Inc. Systems, Inc $1,999 OR LESS Plum Foundation, The Richard G. Brennan Bright Foundation, The ▶▶Company logo in the program Edward P. Evans Foundation Public Library Service (PLOS) Tishcon Corp Distribution of company brochure at the Gabrielle’s Angel Foundation Rebiotix, Inc. University of California (CBHA) ▶▶ for Cancer Research Regulus Therapeutics Inc University of Oklahoma sponsored conference Ipsen Bioscience Scholar Rock, Inc. Foundation (Harold Hamm Diabetes Center) Kadmon Corporation, LLC SILVER The Pershing Square Foundation AbbVie Inc. BRONZE Regeneron Pharmaceuticals Inc. Biolegend Company of Biologists (JCS) GOLD BrighFocus Foundation Edison Pharmaceuticals, Inc. Acceleron Pharma, Inc. Calico Life Science Enzo Life Sciences, Inc. Antibodies Incorporated DaVita (Total Renal Care, Inc.) Mebias Discovery LLC Avanti Polar Lipids, Inc Duke-NUS Metabolic Solutions Cydan Development. Inc. Genentech, Inc Development Co LLC Danone Genentech, Inc New England BioLabs, Inc. Janssen RnD, LLC (Johnson&Johnson) Growth Hormone Research Society Ono Pharmaceuticals Kevin Turner Immune Design Corp Penn State Center for RNA March of Dimes Jae Joung Molecular Biology (CRMB) Mead Johnson & Company, Novartis Institutes of The Rockerfeller University LLC (MJN) Biomedical Research, Inc. (Journal of Cell Biology) Paul J. Davis, MD

If you are interested in providing support please contact: Sherri-Gae Scott, Ph.D., Grants Proposal Manager, [email protected]

Register Now! www.faseb.org/SRC 23 e•Engag or e•C pl o x n t E r Call for 2019 Conference • i n b r u

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Organize a FASEB SRC w w c Organizing meetings is a community r w s responsibility, providing valuable learning . / experiences and fostering team building, which f a r g helps to promote your career. If you are a science s eb . o professional holding an advanced medical or doctoral degree and are active in scientific research, you may submit a proposal to organize a conference with FASEB. Submission deadline for 2019 conferences: Wednesday, September 27, 2017 We invite you to submit a proposal for consideration. For additional information and submission guidelines, visit www.faseb.org/SRC and click on Organize an SRC. FASEB SRCs are organized by leading biomedical researchers in their field. Conferences are organized to present and discuss new and innovative research in those areas undergoing rapid scientific advances. Conferences are held in both U.S. and international locations. The FASEB Science Research Conferences Advisory Committee reviews and selects conferences from submitted proposals. Organizers are not required to be affiliated with FASEB to submit a proposal. All conferences are scheduled two years in advance. Organizers are responsible for assembling the scientific content of the conference. Upon conference acceptance by FASEB, full-time SRC staff assist organizers with sponsorship and conference logistics. Join the FASEB SRC program and expand and shape the direction of research in your community.

www.faseb.org/SRC