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Abstract Book ESMO 22Nd World Congress on Gastrointestinal Cancer, 2020 Virtual Abstract Book ESMO 22nd World Congress on Gastrointestinal Cancer, 2020 Virtual 1-4 July 2020 Guest Editors: Scientific Committee, ESMO 22nd World Congress on Gastrointestinal Cancer, 2020 Virtual Publication of this Abstract book is supported by Imedex, an HMP Company. An Official Journal of the European Society for Medical Oncology and the Japanese Society of Medical Oncology Editor-in-Chief Deputy Editor F. André, Villejuif, France D. G. Haller, Philadelphia, Pennsylvania, USA Associate Editors Urogenital tumors Gynecological tumors Onco-Immunology G. Attard, Sutton, UK B. Monk, Phoenix, Arizona, USA P. Ascierto, Naples, Italy S. Pignata, Naples, Italy Gastrointestinal tumors Molecular and surgical pathology Melanoma D. Arnold, Hamburg, Germany I. I. Wistuba, Houston, Texas, USA G. Long, Sydney, Australia J. Tabernero, Barcelona, Spain Hematological malignancies Early drug development A. Cervantes, Valencia, Spain K. Tsukasaki, Saitama, Japan C. Massard, Villejuif, France Breast tumors Supportive care Liaison with ESMO F. André, Villejuif, France K. Jordan, Heidelberg, Germany P. Garrido, Madrid, Spain C. Sotiriou, Brussels, Belgium Epidemiology Industry corner: perspectives and controversies K. Dhingra, New York, New York, USA Thoracic tumors P. Boffetta, New York, New York, USA M. D. Hellmann, New York, New York, USA P. Lagiou, Athens, Greece Methodology S. Peters, Lausanne, Switzerland Preclinical and experimental science L. Belin, Paris, France J. F. Vansteenkiste, Leuven, Belgium T. U. E. Helleday, Sheffield, UK D. Giannarelli, Rome, Italy S. Yano, Kanazawa, Japan Precision medicine A. Hinke, Düsseldorf, Germany C. Swanton, London, UK V. Moreno, Barcelona, Spain Head and neck tumors Bioinformatics Social media A. T. C. Chan, Shatin, Hong Kong N. McGranahan, London, UK P. Aftimos, Brussels, Belgium Editorial Board M. S. Aapro, Genolier, Switzerland C. Ishioka, Sendai, Japan S. I. Ou, Orange, California, USA M. Alsina, Barcelona, Spain H. Iwata, Aichi, Japan C. Pezaro, Melbourne, Australia Y. Ando, Nagoya, Japan F. Janku, Houston, Texas, USA P. Pfeiffer, Odense, Denmark I. Barnes, Oxford, UK N. Katsumata, Kawasaki, Japan S. Postel-Vinay, Villejuif, France J. Bellmunt, Boston, Massachusetts, USA T. Kawaguchi, Osaka, Japan A. Psyrri, New Haven, Connecticut, USA B. Besse, Villejuif, France N. Kiyota, Kobe, Japan D. Quinn, Los Angeles, California, USA J. Beyer, Zurich, Switzerland C. La Vecchia, Milan, Italy S. S. Ramalingam, Atlanta, Georgia, USA J.-Y. Blay, Lyon, France P. N. Jr Lara, Sacramento, California, USA M. Reck, Grosshansdorf, Germany C. Bokemeyer, Hamburg, Germany J. M. Larkin, London, UK B. Rini, Cleveland, Ohio, USA E. Bria, Verona, Italy S. Loi, Melbourne, Australia R. Rosell, Badalona, Spain E. F. Burgess, Charlotte, North Carolina, USA S. Loibl, Neu-Isenburg, Germany A. D. Roth, Geneva, Switzerland P. G. Casali, Milan, Italy F. Lordick, Leipzig, Germany S. Saji, Fukushima, Japan F. Ciardiello, Naples, Italy Y. Loriot, Villejuif, France R. Salazar, Barcelona, Spain A. Comandone, Turin, Italy D. Lorusso, Milan, Italy T. Sato, Osaka, Japan P. G. Corrie, Cambridge, UK T. Macarulla Mercade, Barcelona, Spain M. Scartozzi, Ancona, Italy J. Cortés, Madrid, Spain M. Martin Jimenez, Madrid, Spain N. Schmitz, Hamburg, Germany G. Curigliano, Milan, Italy S. Matsui, Tokyo, Japan H.-J. Schmoll, Halle, Germany A. Di Leo, Prato, Italy J. Maurel, Barcelona, Spain Q. Shi, Rochester, Minnesota, USA R. Dienstmann, Barcelona, Spain G. McArthur, Melbourne, Australia A. F. Sobrero, Genoa, Italy T. Dorff, Los Angeles, California, USA F. Meric-Bernstam, Houston, Texas, USA G. Sonpavde, Birmingham, Alabama, USA A. Eniu, Cluj-Napoca, Romania S. Michiels, Villejuif, France V. Subbiah, Houston, Texas, USA B.-C. Goh, Singapore, Singapore H. Minami, Kobe, Japan S. Takahashi, Tokyo, Japan A. Goldhirsch, Milan, Italy T. S. K. Mok, Shatin, Hong Kong N. Turner, London, UK P. Grimison, Sydney, Australia M. Muto, Kyoto, Japan E. Van Cutsem, Leuven, Belgium A. Grothey, Rochester, Minnesota, USA Y. Nishimura, Osaka-Sayama, Japan Y.-L. Wu, Guangzhou, China S. Halabi, Durham, North Carolina, USA K. Nishio, Osaka-Sayama, Japan J. C.-H. Yang, Taipei, Taiwan D. M. Hyman, New York, New York, USA S. Novello, Turin, Italy T. Yoshino, Chiba, Japan M. Ignatiadis, Brussels, Belgium M. Ogura, Gifu, Japan A. X. Zhu, Boston, Massachusetts, USA D. H. Ilson, New York, New York, USA A. Ohtsu, Kashiwa, Japan A. Inoue, Sendai, Japan I. Okamoto, Fukuoka, Japan Editors Emeriti F. Cavalli, Bellinzona, Switzerland D. J. Kerr, Oxford, UK J.-C. Soria, Paris, France J. B. Vermorken, Edegem, Belgium Executive Editor: L. H. Rowett Editorial Office: P. Minotti Bernasconi, G. Porcu, Annals of Oncology, Via Ginevra 4, 6900 Lugano, Switzerland Annals of Oncology is covered in C.A.B. 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