Denotations & Old Terminologies Used in Homopathy
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Pustular Acne, Staphyloderma and Its Treatment with Tolbutamide
Canad. M. A. J. April 15,1959, vol. 80 COHEN AND COHEN: AcNE AND TOLBUTAMIDE 629 PUSTULAR ACNE, STAPHY- a reliable guide to the androgen level.4 It has been LODERMA AND ITS TREAT. our custom to prescribe cestrogens in severe cases, MENT WITH TOLBUTAMIDE* in males and also in females with exacerbations at the menstrual period. We use diethylstilbcestrol, J. L. COHEN, M.D., Windsor, Ont. and 0.25 mg. daily for 12-15 days of the month for ALAN D. COHEN, M.D.,t males, and in females 0.25 mg. once daily from Detroit, Mich. seven days after completion of the menses until THE PROBLEM OF ACNE, speaking pathologically, is the onset of the next period. This avoids distur- not very serious, but if we consider the total picture bance of the cycle of ovulation. (Estrogens inhibit including psychological ramifications which affect the gonad-stimulating function of the anterior the social life of the individual, it becomes a pituitary gland.4 One must be careful not to use disease of major importance. This aspect has been excessive doses because they may inhibit ovulation, well documented by Marshall.' and in the male gyrecomastia may result. The treatment of acne is not a simple "magic Bacteria are an important factor in the develop- bullet" affair. The specific systemic measures usually ment of follicular plugging and pustular lesions employed in addition to local therapy depend with acne. Cocci have been found in the follicles upon the seriousness of the skin condition. These and not in the inflammatory infiltrate about the additional measures include hormone therapy, sebaceous glands. -
Manual of Bacteriology
m 4-1 /fo3 L CORNELL UNIVERSITY. THE THE GIFT OF ROSWELL P. FLOWER FOR THE USE OF THE N. Y. STATE VETERINARY COLLEGE ,,,. ^ 1897 8394-1 v3 Cornell University Library OR 41.M95 1903 Manual of bacteriology, 3 1924 000 225 965 Cornell University Library The original of tiiis book is in tine Cornell University Library. There are no known copyright restrictions in the United States on the use of the text. http://www.archive.org/details/cu31924000225965 MANUAL OF BACTERIOLOGY \ > rhe?yi><^- MANUAL OF BACTERIOLOGY BY ROBERT MUIR; M.A., M.D., F.R.C.P.Ed. PROFESSOR OF PATHOLOGY, UNIVERSITY OF GLASGOW, AND JAMES RITCHIE, M.A., M.D., B.Sc. T READER IN PATHOLOGY, UNIVERSITY OF OXFORD, AMERICAN EDITION (WITH ADDITIONS), REVISED AND EDITED FROM THE THIRD ENGLISH EDITION BY NORMAN MAC LEOD HARRIS, M.B. (Tor.) ASSOCIATE IN BACTERIOLOGY, THE JOHNS HOPKINS UNIVERSITY, BALTIMQRE. WITH ONE HUND/t^D &= i^ENlPC^LLUSTRATIONS. LIBRARY. THE MACMILLAN COMPANY. LONDON: MACMILLAN & CO., Ltd. 1903 T Jill rights reserved. -7 . "^ '%C; No. X5 G^ Copyright, 1903, By the macmillan company. Set up and electrotyped February, 1903. Norivood Press J. S. Cushing & Co. — Berwick & Smith Norwood, Mass., U.S.A. PREFACE TO THE AMERICAN EDITION. In presenting this the American edition of the well-known and appreciated work of Doctors Muir and Ritchie, the en- deavour has been made to add to the value of the book by giving adequate expression to the best in American laboratory methods and research, and, at the same time, to augment the general scope of the work -without eliminating the personal impress of the authors. -
The Safety and Efficacy of Phage Therapy for Superficial Bacterial
antibiotics Review The Safety and Efficacy of Phage Therapy for Superficial Bacterial Infections: A Systematic Review Angharad Steele 1 , Helen J. Stacey 2, Steven de Soir 3,4 and Joshua D. Jones 1,* 1 Infection Medicine, Edinburgh Medical School: Biomedical Sciences, University of Edinburgh, Chancellor’s Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK 2 Edinburgh Medical School, University of Edinburgh, Chancellor’s Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK 3 Laboratory for Molecular and Cellular Technology, Queen Astrid Military Hospital, Rue Bruyn, 1120 Brussels, Belgium 4 Cellular & Molecular Pharmacology, Louvain Drug Research Institute, Université Catholique de Louvain (UCLouvain), avenue E. Mounier 73, 1200 Brussels, Belgium * Correspondence: [email protected] Received: 29 September 2020; Accepted: 23 October 2020; Published: 29 October 2020 Abstract: Superficial bacterial infections, such as dermatological, burn wound and chronic wound/ulcer infections, place great human and financial burdens on health systems globally and are often complicated by antibiotic resistance. Bacteriophage (phage) therapy is a promising alternative antimicrobial strategy with a 100-year history of successful application. Here, we report a systematic review of the safety and efficacy of phage therapy for the treatment of superficial bacterial infections. Three electronic databases were systematically searched for articles that reported primary data about human phage therapy for dermatological, burn wound or chronic wound/ulcer infections secondary to commonly causative bacteria. Two authors independently assessed study eligibility and performed data extraction. Of the 27 eligible reports, eight contained data on burn wound infection (n = 156), 12 on chronic wound/ulcer infection (n = 327) and 10 on dermatological infections (n = 1096). -
WO 2014/134709 Al 12 September 2014 (12.09.2014) P O P C T
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2014/134709 Al 12 September 2014 (12.09.2014) P O P C T (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 31/05 (2006.01) A61P 31/02 (2006.01) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, PCT/CA20 14/000 174 DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, 4 March 2014 (04.03.2014) KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (25) Filing Language: English OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (26) Publication Language: English SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, (30) Priority Data: ZW. 13/790,91 1 8 March 2013 (08.03.2013) US (84) Designated States (unless otherwise indicated, for every (71) Applicant: LABORATOIRE M2 [CA/CA]; 4005-A, rue kind of regional protection available): ARIPO (BW, GH, de la Garlock, Sherbrooke, Quebec J1L 1W9 (CA). GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (72) Inventors: LEMIRE, Gaetan; 6505, rue de la fougere, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Sherbrooke, Quebec JIN 3W3 (CA). -
Poisoning by Medical Plants
ARCHIVES OF ArchiveArch Iran Med.of SID February 2020;23(2):117-127 IRANIAN http www.aimjournal.ir MEDICINE Open Systematic Review Access Poisoning by Medical Plants Mohammad Hosein Farzaei, PhD1; Zahra Bayrami, PhD2; Fatemeh Farzaei, PhD1; Ina Aneva, PhD3; Swagat Kumar Das, PhD4; Jayanta Kumar Patra, PhD5; Gitishree Das, PhD5; Mohammad Abdollahi, PhD2* 1Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran 2Toxicology and Diseases Group, Pharmaceutical Sciences Research Center (PSRC), The Institute of Pharmaceutical Sciences (TIPS), and School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran 3Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria, Bulgaria 4Department of Biotechnology, College of Engineering and Technology, BPUT, Bhubaneswar 751003, Odisha, India 5Research Institute of Biotechnology & Medical Converged Science, Dongguk University-Seoul, Goyangsi 10326, Republic of Korea Abstract Background: Herbal medications are becoming increasingly popular with the impression that they cause fewer side effects in comparison with synthetic drugs; however, they may considerably contribute to acute or chronic poisoning incidents. Poison centers receive more than 100 000 patients exposed to toxic plants. Most of these cases are inconsiderable toxicities involving pediatric ingestions of medicinal plants in low quantity. In most cases of serious poisonings, patients are adults who have either mistakenly consumed a poisonous plant as edible or ingested the plant regarding to its medicinal properties for therapy or toxic properties for illegal aims. Methods: In this article, we review the main human toxic plants causing mortality or the ones which account for emergency medical visits. Articles addressing “plant poisoning” in online databases were listed in order to establish the already reported human toxic cases. -
Clinical Laboratory Preparedness and Response Guide
TABLE OF CONTENTS Table of Contents ...................................................................................................................................................................................... 2 State Information ....................................................................................................................................................................................... 7 Introduction .............................................................................................................................................................................................. 10 Laboratory Response Network (LRN) .......................................................................................................................................... 15 Other Emergency Preparedness Response Information: .................................................................................................... 19 Radiological Threats ......................................................................................................................................................................... 21 Food Safety Threats .......................................................................................................................................................................... 25 BioWatch Program ............................................................................................................................................................................ 27 Bio Detection Systems -
Chapter 26 BIOSAFETY Appendix B. Pathogen and Toxin Lists B.1
Chapter 26 BIOSAFETY ____________________ Appendix B. Pathogen and Toxin Lists B.1 Introduction and Scope Pathogens and toxins are discussed in detail in Work Process B.3.d, Pathogenic Agents and Toxins, of this manual. This appendix lists the following biological agents and toxins presented in Work Process B.3.d: Human etiologic agents (pathogens) from Appendix B of the NIH Guidelines Select agents and toxins from the National Select Agent Registry (NSAR) Plant pathogens previously identified by U.S. Department of Agriculture (USDA) These lists are provided for convenience in this manual, but may not reflect the actual regulatory list or applicable agents or materials. Regulatory sources, standards, and Web links noted in this appendix and Work Process B.3.d should be consulted to confirm applicable agents or toxins. B.2 NIH Guidelines Human Etiologic Agents This section provides a list of human pathogens and their Risk Group (RG) 2, RG3, and RG4 designations as excerpted from Appendix B, Classification of Human Etiologic Agents on the Basis of Hazard, of the NIH Guidelines, amendment effective November 6, 2013. B.2.1 Risk Group 1 Agents RG1 agents are not associated with disease in healthy adult humans. Examples of RG1 agents include asporogenic Bacillus subtilis or Bacillus licheniformis (see NIH Guidelines, Appendix C-IV-A, Bacillus subtilis or Bacillus licheniformis Host-Vector Systems, Exceptions); adeno-associated virus (AAV, all serotypes); and recombinant or synthetic AAV constructs, in which the transgene does not encode either a potentially tumorigenic gene product or a toxin molecule and which are produced in the absence of a helper virus. -
| Oa Tai Ei Rama Telut Literatur
|OA TAI EI US009750245B2RAMA TELUT LITERATUR (12 ) United States Patent ( 10 ) Patent No. : US 9 ,750 ,245 B2 Lemire et al. ( 45 ) Date of Patent : Sep . 5 , 2017 ( 54 ) TOPICAL USE OF AN ANTIMICROBIAL 2003 /0225003 A1 * 12 / 2003 Ninkov . .. .. 514 / 23 FORMULATION 2009 /0258098 A 10 /2009 Rolling et al. 2009 /0269394 Al 10 /2009 Baker, Jr . et al . 2010 / 0034907 A1 * 2 / 2010 Daigle et al. 424 / 736 (71 ) Applicant : Laboratoire M2, Sherbrooke (CA ) 2010 /0137451 A1 * 6 / 2010 DeMarco et al. .. .. .. 514 / 705 2010 /0272818 Al 10 /2010 Franklin et al . (72 ) Inventors : Gaetan Lemire , Sherbrooke (CA ) ; 2011 / 0206790 AL 8 / 2011 Weiss Ulysse Desranleau Dandurand , 2011 /0223114 AL 9 / 2011 Chakrabortty et al . Sherbrooke (CA ) ; Sylvain Quessy , 2013 /0034618 A1 * 2 / 2013 Swenholt . .. .. 424 /665 Ste - Anne -de - Sorel (CA ) ; Ann Letellier , Massueville (CA ) FOREIGN PATENT DOCUMENTS ( 73 ) Assignee : LABORATOIRE M2, Sherbrooke, AU 2009235913 10 /2009 CA 2567333 12 / 2005 Quebec (CA ) EP 1178736 * 2 / 2004 A23K 1 / 16 WO WO0069277 11 /2000 ( * ) Notice : Subject to any disclaimer, the term of this WO WO 2009132343 10 / 2009 patent is extended or adjusted under 35 WO WO 2010010320 1 / 2010 U . S . C . 154 ( b ) by 37 days . (21 ) Appl. No. : 13 /790 ,911 OTHER PUBLICATIONS Definition of “ Subject ,” Oxford Dictionary - American English , (22 ) Filed : Mar. 8 , 2013 Accessed Dec . 6 , 2013 , pp . 1 - 2 . * Inouye et al , “ Combined Effect of Heat , Essential Oils and Salt on (65 ) Prior Publication Data the Fungicidal Activity against Trichophyton mentagrophytes in US 2014 /0256826 A1 Sep . 11, 2014 Foot Bath ,” Jpn . -
ICAR-JRF Tutorial Question Bank. 2014. Veterinary College, KVAFSU
KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR-585 401 ICAR-JRF [Indian Council of Agricultural Research, New Delhi] TUTORIAL QUESTION BANK FOR THE BENEFIT OF: FINAL YEAR B.V.Sc & A.H STUDENTS VETERINARY COLLEGE, VINOBANAGAR SHIMOGA-577204 Tutorial Classes Conducted under SCP- TSP Grant from the Government of Karnataka [FY: 2013-14] Organized by: VETERINARY COLLEGE, SHIMOGA Karnataka Veterinary, Animal &Fisheries Sciences University Vinobanagar, Shimoga-577204 E.mail: [email protected] Tel: 08182-651001 KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR-585 401 ICAR-JRF 1 [Indian Council of Agricultural Research, New Delhi] TUTORIAL QUESTION BANK FOR THE BENEFIT OF: FINAL YEAR B.V.Sc & A.H STUDENTS VETERINARY COLLEGE, VINOBANAGAR SHIMOGA-577204 Prepared by: Dr. PRAKSH NADOOR Professor& Head Department of Pharmacology & Toxicology Veterinary College, Shimoga-577204 Dr. LOKESH L.V Assistant Professor Department of Pharmacology & Toxicology Veterinary College, Shimoga-577204 and Dr.NAGARAJA . L Assistant Professor Department of Veterinary Medicine Veterinary College, Shimoga-577204 2 FORE WORD The Indian Council of Council Agricultural Research [ICAR],New Delhi is the apex body for co-ordinating, guiding and managing research and education in agriculture including horticulture, fisheries and animal sciences in the entire country. With 99 ICAR institutes and 53 agricultural universities (including veterinary universities) spread across the country this is one of the largest national agricultural systems in the world. Apart from above mandates of the Council, it is also encourgining student’s to undertake quality higher education in veterinary, agriculture, horticulture, forestry and fishery sciences, in a way to produce quality scientists required for not only for its premier research institutes spread across the country, but also to scale up with human resource development. -
Investigation of How Endoplasmic Reticulum Stress Causes Insulin Resistance and Neuroinflammation
Durham E-Theses INVESTIGATION OF HOW ENDOPLASMIC RETICULUM STRESS CAUSES INSULIN RESISTANCE AND NEUROINFLAMMATION BROWN, MAX,ADAM How to cite: BROWN, MAX,ADAM (2015) INVESTIGATION OF HOW ENDOPLASMIC RETICULUM STRESS CAUSES INSULIN RESISTANCE AND NEUROINFLAMMATION , Durham theses, Durham University. Available at Durham E-Theses Online: http://etheses.dur.ac.uk/11438/ Use policy The full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-prot purposes provided that: • a full bibliographic reference is made to the original source • a link is made to the metadata record in Durham E-Theses • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders. Please consult the full Durham E-Theses policy for further details. Academic Support Oce, Durham University, University Oce, Old Elvet, Durham DH1 3HP e-mail: [email protected] Tel: +44 0191 334 6107 http://etheses.dur.ac.uk 2 INVESTIGATION OF HOW ENDOPLASMIC RETICULUM STRESS CAUSES INSULIN RESISTANCE AND NEUROINFLAMMATION Volume I Max Adam Brown This thesis is submitted as part of the requirements for the award of Degree of Doctor of Philosophy School of Biological and Biomedical Sciences Durham University July 2015 ABSTRACT Endoplasmic reticulum (ER) stress is caused by the accumulation of mis/unfolded proteins in the ER. ER stress signalling pathways termed the unfolded protein response are employed to alleviate ER stress through increasing the folding capacity and decreasing the folding demand of the ER as well as removing mis/unfolded proteins. -
Survival After an Intentional Ingestion of Crushed Abrus Seeds
UC Irvine Western Journal of Emergency Medicine: Integrating Emergency Care with Population Health Title Survival after an Intentional Ingestion of Crushed Abrus Seeds Permalink https://escholarship.org/uc/item/6mk8r34r Journal Western Journal of Emergency Medicine: Integrating Emergency Care with Population Health, 9(3) ISSN 1936-900X Authors Reedman, Lisa Shih, Richard D Hung, Oliver Publication Date 2008 Peer reviewed eScholarship.org Powered by the California Digital Library University of California CASE REP O RT Survival after an Intentional Ingestion of Crushed Abrus Seeds Lisa Reedman, MD* * Morristown Memorial Hospital Richard D. Shih, MD*† † New Jersey Medical School Oliver Hung, MD* Supervising Section Editor: Brandon K. Wills, DO, MS Submission history: Submitted December 23, 2007; Revision Received March 6, 2008; Accepted March 6, 2008. Reprints available through open access at www.westjem.org Abrus precatorius seeds contain one of the most potent toxins known to man. However, because of the seed’s outer hard coat the vast majority of ingestions cause only mild symptoms and typically results in complete recovery. If the seeds are crushed and then ingested, more serious toxicity, including death, can occur. We present a case of a man who survived an intentional ingestion of crushed Abrus seeds after he was treated with aggressive gastric decontamination and supportive care. [WestJEM. 2008;9:157-159.] INTRODUCTION Abrus precatorius is a vine native to India and other tropical and subtropical areas of the world. Since introduction to Florida and the Caribbean, it is now commonly found throughout these areas and in the southern United States.1 It is known by a variety of names, including jequirty bean, rosary pea, prayer bead, crab’s eye, and love bean.2 The vine has pods with oval seeds and a hard glossy shell. -
Table I. Genodermatoses with Known Gene Defects 92 Pulkkinen
92 Pulkkinen, Ringpfeil, and Uitto JAM ACAD DERMATOL JULY 2002 Table I. Genodermatoses with known gene defects Reference Disease Mutated gene* Affected protein/function No.† Epidermal fragility disorders DEB COL7A1 Type VII collagen 6 Junctional EB LAMA3, LAMB3, ␣3, 3, and ␥2 chains of laminin 5, 6 LAMC2, COL17A1 type XVII collagen EB with pyloric atresia ITGA6, ITGB4 ␣64 Integrin 6 EB with muscular dystrophy PLEC1 Plectin 6 EB simplex KRT5, KRT14 Keratins 5 and 14 46 Ectodermal dysplasia with skin fragility PKP1 Plakophilin 1 47 Hailey-Hailey disease ATP2C1 ATP-dependent calcium transporter 13 Keratinization disorders Epidermolytic hyperkeratosis KRT1, KRT10 Keratins 1 and 10 46 Ichthyosis hystrix KRT1 Keratin 1 48 Epidermolytic PPK KRT9 Keratin 9 46 Nonepidermolytic PPK KRT1, KRT16 Keratins 1 and 16 46 Ichthyosis bullosa of Siemens KRT2e Keratin 2e 46 Pachyonychia congenita, types 1 and 2 KRT6a, KRT6b, KRT16, Keratins 6a, 6b, 16, and 17 46 KRT17 White sponge naevus KRT4, KRT13 Keratins 4 and 13 46 X-linked recessive ichthyosis STS Steroid sulfatase 49 Lamellar ichthyosis TGM1 Transglutaminase 1 50 Mutilating keratoderma with ichthyosis LOR Loricrin 10 Vohwinkel’s syndrome GJB2 Connexin 26 12 PPK with deafness GJB2 Connexin 26 12 Erythrokeratodermia variabilis GJB3, GJB4 Connexins 31 and 30.3 12 Darier disease ATP2A2 ATP-dependent calcium 14 transporter Striate PPK DSP, DSG1 Desmoplakin, desmoglein 1 51, 52 Conradi-Hu¨nermann-Happle syndrome EBP Delta 8-delta 7 sterol isomerase 53 (emopamil binding protein) Mal de Meleda ARS SLURP-1