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Categoryterm Count % Pvalue Genes List Total Pop Hitspop Category Term Count % PValue Genes List PopTotal HitsPop TotalFold EnrichmentBonferroniBenjaminiFDR GOTERM_CC_DIRECTGO:0005743~mitochondrial60 8.96 ####### innerMRPL40, membrane MRPS34,611 441 NDUFAF6,18224 4.058 CYC1, ######TIMM17B,##### NDUFAB1,#### MPV17, ROMO1, NDUFAF3, RPS3, MRPL36, ATP5L, SLC25A26, MRPL52, NDUFB10, NDUFA13, COX4I1, TMEM70, TMEM126A, ERAL1, MRPS6, MRPS7, TIMM8B, NDUFA11, MRPL49, SMIM20, SLC25A39, MRPL48, SURF1, MRPL43, NDUFB7, MRPS14, MRPS12, COX7B, TIMM10, ATP5G1, PTPMT1, CHCHD6, NDUFB1, MRPL11, MRPL10, MRPL13, MRPL12, MRPL17, MRPL55, MRPL58, NDUFA2, NDUFA3, MRPS28, MRPS23, PHB, MRPS24, COX8A, UQCC2, MRPL23, MRPL27, MTFP1, RHBDL1, FOXRED1, SPNS1 GOTERM_CC_DIRECTGO:0005739~mitochondrion106 15.8 ####### MRPL40, TUSC2,611 1331 MRPS34,18224 CMC1,2.375 TNNC1,###### MALSU1,##### ####DTYMK, ROMO1, MPV17, GFER, MUTYH, IDH3G, DDX28, HTRA2, SLC25A26, SMIM4, RPUSD4, NUDT1, RPUSD3, LYRM4, RPUSD1, TMEM126A, TIMM8B, NME6, DCAF5, PYCR1, NME3, MRPL49, ADSL, FMC1, MPST, SIVA1, HSD17B10, HAX1, MRPS14, MRPS12, COX7B, CHCHD2, SDHAF2, CHCHD6, FTH1, SDHAF1, FIS1, PSMB3, GCSH, NAXE, MRPL58, NTHL1, DNAJA3, TMEM223, MRPS28, MRPS23, PHB, MRPS24, HS1BP3, COA5, FOXRED1, COX14, COA3, NIF3L1, NDUFAF8, AMT, CYC1, PRDX4, ECHDC3, GPX1, ACOT8, CTU1, CTU2, ATP5L, FUNDC2, TMEM70, COX4I1, NDUFA13, ERAL1, MRPS7, NDUFA11, CCDC51, EMC8, TMEM186, AS3MT, TSTD1, BID, NDUFB7, TIMM10, ATP5G1, PTPMT1, NDUFB1, MRPL10, MRPL12, PARS2, PYCARD, PTS, PDK2, NDUFA3, PDF, MACROD1, UQCC2, PRELID1, MRPL23, TMEM160, SMDT1, C21ORF2, OXLD1, MTFP1, BOLA1 GOTERM_BP_DIRECTGO:0070125~mitochondrial23 3.43 ####### translationalMRPL40, MRPL52,549 elongation85 MRPS34,16792 8.276MRPS28,###### MRPS14,##### MRPS23,#### MRPS12, MRPS24, MRPS6, MRPS7, MRPL11, MRPL23, MRPL10, MRPL13, MRPL12, MRPL27, MRPL17, MRPL36, MRPL49, MRPL55, MRPL48, MRPL58, MRPL43 GOTERM_BP_DIRECTGO:0070126~mitochondrial23 3.43 ####### translationalMRPL40, MRPL52,549 termination86 MRPS34,16792 MRPS28,8.18 ###### MRPS14,##### MRPS23,#### MRPS12, MRPS24, MRPS6, MRPS7, MRPL11, MRPL23, MRPL10, MRPL13, MRPL12, MRPL27, MRPL17, MRPL36, MRPL49, MRPL55, MRPL48, MRPL58, MRPL43 GOTERM_MF_DIRECTGO:0003735~structural33 4.93 ####### constituentMRPS34, of MRPS14, 544ribosome222 RPL13,16881 MRPS12,4.613 ######RPLP2, #####RPS3, ####MRPL11, MRPL10, MRPL13, MRPL12, MRPL17, RPL8, MRPL36, RPL26L1, MRPL55, FAU, MRPL57, SLC25A26, RPS21, MRPL52, MRPS23, MRPS24, RPL27, MRPS6, MRPS7, RPS5, MRPL23, RPS18, RPS16, MRPL27, MRPL49, SLC25A39, MRPL43 GOTERM_MF_DIRECTGO:0005515~protein362 54 binding####### MRPL40, HM13,544 8785 MCRIP2,16881 EFNA1,1.279 RPL13,###### MALSU1,##### ####CHMP6, USE1, TRAPPC2L, RPLP2, GFER, CXORF40A, SLC52A2, WDR74, MVB12A, GET4, TMEM147, HTRA2, IFT20, NAA10, PQBP1, TMEM185A, LSM2, JAGN1, GNG4, EIF2B3, AUP1, RPUSD4, ROCK1, RPUSD3, EMG1, RCOR1, NUDT14, DCTN3, YIF1A, MED19, UXT, RPS18, PPP1CA, NME3, BAZ1A, RPS16, ABT1, NME1, SPAG4, UBL4A, MRPL49, TUBA4A, CAMK1, ZNHIT1, EFNA4, AMFR, MRPL48, SPATC1L, MAD2L2, SURF1, MRPL43, ZNHIT3, SIVA1, HSD17B10, TALDO1, DBNDD2, AHCY, CHCHD2, ARF5, ASB13, NPRL2, GPR143, CHCHD6, SDHAF2, VPS72, TMEM128, ACD, DRAP1, SAC3D1, DUSP15, GCSH, NAXE, NTHL1, LAMTOR5, SSSCA1, C7ORF50, MOCS3, TSEN54, LAMTOR4, LAMTOR1, C22ORF39, PHB, CCDC153, DUSP23, DALRD3, UPK3A, PMF1, ZNF524, RPS5, SYNE4, GGT7, CNIH4, NUTF2, SPNS1, NCOR1, SNRNP25, POP7, FAM96B, NIF3L1, KIAA0368, RAB5C, TSG101, COPS6, AP2S1, COPRS, COPS9, CD151, HSBP1, RABAC1, TRAPPC6A, HSF1, NUBP2, SHARPIN, ACTR5, NSMCE1, NSMCE2, GPX7, DYNC1H1, RXFP4, STX5, SPACA3, NDUFB10, FLOT2, EXOSC4, EXOSC5, NDUFA13, EXOSC1, LRRC29, ZCCHC17, KLHDC3, TAF10, CH GOTERM_BP_DIRECTGO:0006412~translation34 5.07 ####### MRPS14, RPL13,549 253 MRPS12,16792 RPS6KB2,4.11 ###### RPLP2,##### RPS3,#### MRPL11, MRPL10, MRPL13, MRPL17, RPL8, MRPL36, RPL26L1, MRPL55, FAU, MRPL57, SLC25A26, RPS21, MRPL52, MRPS23, PDF, MRPS24, RPL27, MRPS6, MRPS7, RPS5, MRPL23, RPS18, RPS16, MRPL27, MRPL49, SLC25A39, NHP2, MRPL43 GOTERM_CC_DIRECTGO:0005840~ribosome23 3.43 ####### MRPS34, MRPS28,611 166 MRPS14,18224 4.133MRPS23,###### RPL13,##### RPL27,#### RPLP2, MRPS7, RPS3, MRPL11, MRPL23, MRPL10, RPS18, MRPL13, RPS16, MRPL27, MRPL17, RPL8, MRPL49, MRPL55, FAU, RPS21, MRPL43 GOTERM_CC_DIRECTGO:0005762~mitochondrial13 1.94 ####### largeMRPL52, ribosomal MRPL11,611 subunit48 MRPL10,18224 8.078MRPL23,###### MRPL13,##### MRPL12,#### MRPL27, MRPL17, MRPL36, MRPL49, MRPL55, MRPL58, MRPL43 GOTERM_CC_DIRECTGO:0005761~mitochondrial10 1.49 ####### ribosomeMRPL40, MRPL11,611 28 MRPL13,18224 10.65MRPS14,###### MRPS12,##### MRPS24,#### MRPL49, MRPL57, MRPL48, MRPL43 GOTERM_CC_DIRECTGO:0005654~nucleoplasm141 21 ####### EIF6, TNNC1,611 2784CDKN2AIPNL,18224 1.511 RPS6KB2,###### CBX8,##### MAF1,#### AIP, MVB12A, DPY30, MUTYH, EIF4EBP1, IDH3G, CLP1, CDKN2D, PQBP1, FAU, ACIN1, LSM2, MLST8, PPP4C, RPP21, RREB1, EMG1, RCOR1, RRP9, RNASEH2A, SLTM, ADRM1, RPS18, PPP1CA, RPS16, DNTTIP1, SNRPC, MAD2L2, SIVA1, SSH1, ANAPC15, ZNRD1, ANAPC11, PSMA7, VPS72, PSMB4, ACD, C1ORF56, METTL1, PSMB3, RPS21, NAXE, THAP11, NTHL1, TSEN54, PHB, SUV39H1, PMF1, RPS5, PPIH, WDR4, BABAM1, NUTF2, NELFE, NCOR1, POP7, SNRNP25, PUF60, FAM96B, ARID4A, ZMAT5, COPS6, YLPM1, COPRS, COPS9, HSBP1, RPS3, HSF1, PRMT7, GPKOW, NSMCE1, NSMCE2, HIKESHI, TPR, PSMD8, STX5, BRF2, EXOSC4, EXOSC5, TMEM70, NDUFA13, EXOSC1, CCDC51, TAF10, TBCB, CFAP20, KPNA7, THOC6, UROD, NSD1, NHP2, THOC3, NXT1, ING4, POLR2G, UTP4, POLR2L, POLR2J, POLR2I, SF3B5, POLR2C, SMUG1, ZNF174, RPA3, MRPL10, CHD8, NUDT22, CHD2, KDM3B, C11ORF1, NENF, GEMIN7, RBM25, TSEN34, CHD3, GPS1, PDK2, RSG1, POLR3K, AKIP1, MSRB1, AGTRAP, APRT, TP53RK, MPG, PRELID1, MED30, PSMD13, SP1, CMTM8, LSM10, PHF5A, TRMT112, CENPX, VPS25 GOTERM_CC_DIRECTGO:0005759~mitochondrial30 4.48 ####### matrixHSD17B10,611 ATP5E,327 SDHAF4,18224 2.736 AMT, MALSU1,###### #####DTYMK, NDUFAB1,0 SDHAF2, SDHAF1, ACSF2, RPS3, GPX1, IDH3G, PARS2, BLOC1S1, GCSH, MRPL58, NAXE, LIPT2, DNAJA3, ARL2, PDK2, NUDT1, LYRM4, ERAL1, MMAB, HAGH, UQCC2, PYCR1, PAM16 GOTERM_BP_DIRECTGO:0032981~mitochondrial12 1.79 ####### respiratoryNDUFAF6, 549NDUFA2,chain 63complex NDUFB10,16792 I5.826 assemblyNDUFA3,0.0088 NDUFB7,0.002 NDUFAF8,0.01 NDUFAB1, NDUFA13, FOXRED1, NDUFB1, NDUFA11, NDUFAF3 GOTERM_CC_DIRECTGO:0005758~mitochondrial13 1.94 ####### intermembraneARL2, HAX1,611 spaceNDUFB7,74 18224 COA4,5.24 DTYMK,0.0026 TIMM10,##### CHCHD2,0.01 GFER, CHCHD5, UQCC2, PRELID1, HTRA2, BLOC1S1 GOTERM_BP_DIRECTGO:0033617~mitochondrial7 1.04 ####### respiratoryCOX14, COA5, 549chain COA3, 16complex16792 COA4, IV13.38 CHCHD5, assembly0.0117 SMIM20,0.002 SURF10.01 GOTERM_CC_DIRECTGO:0015935~small8 1.19 ribosomal####### subunitRPS18, RPS16,611 MRPS12,27 18224 FAU,8.837 MRPS6,0.01 RPS21,0.001 RPS5,0.03 RPS3 GOTERM_BP_DIRECTGO:0036258~multivesicular8 1.19 ####### bodyMVB12A, assembly CHMP1A,549 31 TSG101,16792 7.893CHMP4B,0.0802 CHMP6,0.014 VPS37D,0.08 VPS28, VPS25 GOTERM_BP_DIRECTGO:0039702~viral7 1.04 budding####### viaMVB12A, host ESCRT CHMP1A,549 complex22 TSG101,16792 9.732CHMP4B,0.0888 CHMP6,0.013 VPS37D,0.09 VPS28 GOTERM_MF_DIRECTGO:0044822~poly(A)61 9.1 RNA####### bindingMRPL40, RALY,544 1129 RPL13,16881 YLPM1,1.677 C1ORF35,0.0495 RPS3,0.017 DDX28,0.13 NUDT16L1, FAU, ZNF106, LSM2, ACIN1, TPR, DYNC1H1, SELENOH, NCBP3, RPUSD4, RPUSD3, EMG1, ERAL1, MRPS7, RRP9, ZCCHC17, SLTM, RPS18, TRNAU1AP, RPS16, ABT1, NME1, CFAP20, RPP25L, SNRPC, NHP2, MRPL43, HSD17B10, UTP4, MRPS14, MRPS12, ERI3, MRPL11, MRPL10, MRPL13, RPL8, CHD2, RPS21, RBM25, CHD3, C7ORF50, MRPS28, MRPS23, MRPS24, RPL27, TPD52L2, RPS5, NOSIP, MRPL27, SECISBP2L, PHF5A, NELFE, PUF60, POP7 GOTERM_BP_DIRECTGO:0032543~mitochondrial8 1.19 ####### translationMRPL10, MRPL23,549 36 MRPS34,16792 6.797MRPS12,0.2058 MRPS24,0.028 MRPS6,0.23 MRPL57, MRPS7 GOTERM_MF_DIRECTGO:0019104~DNA5 0.75N-glycosylase####### MPG, activity MUTYH,544 NTHL1,10 16881 SMUG1,15.52 RPS3 0.1068 0.028 0.28 GOTERM_CC_DIRECTGO:0005747~mitochondrial9 1.34 ####### respiratoryNDUFA2, NDUFB10, 611chain 49complex NDUFA3,18224 I5.478 NDUFB7,0.0865 NDUFAB1,0.009 NDUFA13,0.29 FOXRED1, NDUFB1, NDUFA11 GOTERM_BP_DIRECTGO:0006364~rRNA19 2.84 processing####### UTP4, RPP21,549 EMG1,214 16792 RPL13,2.716 EXOSC4,0.3259 EXOSC5,0.043 SUV39H1,0.4 RPL27, RPLP2, RRP9, EXOSC1, RPS5, RPS3, RPS18, RPS16, RPL8, RPL26L1, FAU, RPS21 GOTERM_MF_DIRECTGO:0019843~rRNA8 1.19 binding####### MRPL11, RPS18,544 40DDX28,16881 EMG1,6.206 RPL8,0.1398 ERAL1,0.03 MRPS7,0.37 RPS5 GOTERM_BP_DIRECTGO:0006413~translational14 2.09 ####### initiationEIF6, RPL13,549 RPLP2,137 16792 RPL27,3.126 RPS5,0.5978 RPS3,0.087 RPS18,0.92 RPS16, RPL8, RPL26L1, FAU, RPS21, YAE1D1, EIF2B3 GOTERM_BP_DIRECTGO:0006626~protein7 1.04 targeting####### BID, to mitochondrionFIS1,549 MTX1,34 TIMM17B,16792 6.297 TIMM10,0.6995 TIMM8B,0.104 AIP1.21 GOTERM_BP_DIRECTGO:0006614~SRP-dependent11 1.64 ####### cotranslationalRPS18, RPS16,549 proteinRPL13,94 16792 RPL8,targeting3.579 RPL26L1, 0.8019to membrane FAU,0.126 RPL27,1.63 RPLP2, RPS21, RPS5, RPS3 GOTERM_BP_DIRECTGO:0006120~mitochondrial8 1.19 ####### electronNDUFA2, transport, NDUFB10,549 49 NDUFA3,NADH16792 to4.994 NDUFB7,ubiquinone0.8069 NDUFAB1,0.119 NDUFA13,1.66 NDUFB1, NDUFA11 GOTERM_BP_DIRECTGO:0019083~viral12 1.79 transcription0.00108 RPS18, RPS16,549 112RPL13,16792 RPL8,3.277 RPL26L1,0.834 FAU,0.12 RPL27,1.81 RPLP2, TPR, RPS21, RPS5, RPS3 GOTERM_CC_DIRECTGO:0005730~nucleolus47 7.01 0.00112 MRPL40, EIF6,611 857UTP4,18224 CDV3,1.636 TSG101,0.3939 POLR2I,0.044 CDKN2AIPNL,1.57 ZNRD1, ANAPC11, MAF1, TRAIP, SMUG1, RPS3, WDR74, P3H4, IDH3G, DDX28, PRMT7, METTL1, NAA10, RPL8, THYN1, PYCARD, CHD2, SCNM1, ZNF106, ACIN1, TSEN34, CHD3, TSEN54, ZNF593,
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