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JOURNAL OF VIROLOGY

Volume 67 August 1993 No. 8

ANIMAL Identification of the Sequence in the Zhengbin Yao, Wallen Jackson, 4464-4473 Cytoplasmic Tail of the Varicella-Zoster Fc Receptor and Charles Grose gpI A Major Transactivator of Varicella-Zoster Virus, the L. P. Perera, J. D. Mosca, W. T. 4474-4483 Immediate- IE62, Contains a Potent Ruyechan, G. S. Hayward, S. E. N-Terminal Activation Domain Straus, and J. Hay Characterization of a Temperature-Sensitive Mutant of the Alice P. W. Poon and Bernard 4497-4503 UL 15 Open Reading Frame of Virus 1 Roizman Recombinant Human Hepatitis Reverse Maria Seifer and David N. 4513-4520 Transcriptase Is Active in the Absence of the Nucleocapsid Standring or the Viral Replication Origin, DR1 African Swine Fever Virus Encodes a Protein Kinase Sally A. Baylis, Alison H. 4549-4556 Which Is Packaged into Virions Banham, Soopayah Vydelingum, Linda K. Dixon, and Geoffrey L. Smith Functional and Immunologic Characterization of Human Richard Wyatt, Nancy Sullivan, 4557-4565 Immunodeficiency Virus Type 1 Envelope Markus Thali, Heinrich Repke, Containing Deletions of the Major Variable Regions David Ho, James Robinson, Marshall Posner, and Joseph Sodroski Efficient Generation of Infectious Recombinant Verne A. Luckow, Stephen C. 4566-4579 Baculoviruses by Site-Specific Transposon-Mediated Lee, Gerard F. Barry, and Peter Insertion of Foreign Genes into a Baculovirus 0. Olins Propagated in Escherichia coli Mutational Analysis of the Residues in the Constance M. T. Mangold and Rolf 4588-4597 Small Envelope Protein E. Streeck Functional Domains of the Type 1 Ayalew Mergia, Lisa W. 4598-4604 Transcriptional Transactivator (Taf) Renshaw-Gegg, Michael W. Stout, Rolf Renne, and Ottmar Herchenroeder Identification and Mapping of the Gene Encoding the Brian Pfeiffer, Zwi N. Berneman, 4611-4620 Glycoprotein Complex gp82-gplO5 of Human Herpesvirus 6 Frank Neipel, Cheow K. Chang, and Mapping of the Neutralizing Epitope Recognized by Suranan Tirwatnapong, and Bala Monoclonal Antibodies Chandran A Poliovirus Minireplicon Containing an Inactive 2A Ruma Pal-Ghosh and Casey D. 4621-4629 Proteinase Is Expressed in Virus-Infected Cells Morrow Analysis of Human Immunodeficiency Virus Type 1 Diane C. Shugars, Marilyn S. 4639-4650 Gene Sequences Present In Vivo Smith, Deborah H. Glueck, Pascale V. Nantermet, Franqoise Seillier-Moiseiwitsch, and Ronald Swanstrom Functional Expression and Characterization of the Tatsuya Tsurumi, Akio Kobayashi, 4651-4658 Epstein-Barr Virus DNA Polymerase Catalytic Subunit Katsuyuki Tamai, Tohru Daikoku, Ryutaro Kurachi, and Yukihiro Nishiyama Complete Nucleotide Sequence of an Amerindian Human Diane Pardi, William M. Switzer, 4659-4664 T-Cell Lymphotropic Virus Type II (HTLV-II) Isolate: Kenneth G. Hadlock, Jonathan E. Identification of a Variant HTLV-II Subtype b from a Kaplan, Renu B. Lal, and Thomas Guaymi Indian M. Folks

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Two Distinct Proteinase Activities Required for the Makoto Hijikata, Hiroto 4665-4675 Processing of a Putative Nonstructural Precursor Protein Mizushima, Tsuyoshi Akagi, of Virus Shigehisa Mori, Nobuko Kakiuchi, Nobuyuki Kato, Torahiko Tanaka, Koichi Kimura, and Kunitada Shimotohno Inhibition of Proteolytic Activity of Poliovirus and Akhteruzzaman Molla, Christopher 4688-4695 Rhinovirus 2A Proteinases by Elastase-Specific Inhibitors U. T. Hellen, and Eckard Wimmer Analysis of the Functional and Host Range-Determining Richard A. Morgan, Ofer 4712-4721 Regions of the Murine Ecotropic and Amphotropic Nussbaum, Daryl D. Muenchau, Envelope Proteins Liming Shu, Larry Couture, and W. French Anderson Graffi : Molecular Cloning and Ming Ru, Chaim Shustik, and Eric 4722-4731 Characterization of the Myeloid Leukemia-Inducing Agent Rassart Deletion of the Vaccinia Virus B5R Gene Encoding a Elizabeth J. Wolffe, Stuart N. 4732-4741 42-Kilodalton Membrane Glycoprotein Inhibits Extracellular Isaacs, and Bernard Moss Virus Envelope Formation and Dissemination The Basic Domain of Rev from Human Immunodeficiency J0rgen Kjems and Phillip A. Sharp 4769-4776 Virus Type 1 Specifically Blocks the Entry of U4/U6. U5 Small Nuclear Ribonucleoprotein in Spliceosome Assembly Immunochemical Analysis of the gpl20 Surface Glycoprotein John P. Moore, Markus Thali, 4785-4796 of Human Immunodeficiency Virus Type 1: Probing the Bradford A. Jameson, Francoise Structure of the C4 and V4 Domains and the Interaction Vignaux, George K. Lewis, of the C4 Domain with the V3 Loop Shu-Wing Poon, MacArthur Charles, Michael S. Fung, Bill Sun, Paul J. Durda, Lennart Akerblom, Britta Wahren, David D. Ho, Quentin J. Sattentau, and Joseph Sodroski The Rule of Six, a Basic Feature for Efficient Replication of Philippe Calain and Laurent Roux 4822-4830 Sendai Virus Defective Interfering RNA Basis for Selective Incorporation of Glycoproteins into the Hussein Y. Naim and Michael G. 4831-4841 Virus Envelope Roth The Herpes Simplex Virus UL37 Protein Is Phosphorylated Allen G. Albright and Frank J. 4842-4847 in Infected Cells Jenkins Location of Intrachain Disulfide Bonds in the VP5* and John T. Patton, Jian Hua, and 4848-4855 VP8* Trypsin Cleavage Fragments of the Rhesus Eric A. Mansell Spike Protein VP4 Effects of Deletions in the Carboxy-Terminal Hydrophobic Len Rasile, Kakoli Ghosh, 4856-4866 Region of Herpes Simplex Virus Glycoprotein gB on Kanakatte Raviprakash, and Intracellular Transport and Membrane Anchoring Hara P. Ghosh Analysis of the Earliest Steps of Hepadnavirus Replication: Josef Kock and Hans-Jurgen 4867-4874 Genome Repair after Infectious Entry into Hepatocytes Does Schlicht Not Depend on Viral Polymerase Activity Separation of the Complex DNA Binding Domain of Mei-Ru Chen, Jaap M. 4875-4885 EBNA-1 into DNA Recognition and Dimerization Middeldorp, and S. Diane Subdomains of Novel Structure Hayward Translation of the Hepatitis B Virus P Gene by Ribosomal Nathalie Fouillot, Sylvie Tlouzeau, 4886-4895 Scanning as an Alternative to Internal Initiation Jean-Michel Rossignol, and Olivier Jean-Jean Expression of Glycoprotein giH-Human Decay-Accelerating Xiaoping Liang, Min Tang, Tim J. 4896-4904 Factor Chimera on the Bovine Herpesvirus 1 Virion via a Zamb, Lorne A. Babiuk, Jacek Glycosyl Phosphatidylinositol-Based Membrane Anchor Kowalski, and Mark L. Tykocinski vif Is Crucial for Human Immunodeficiency Virus Type 1 Uta von Schwedler, Jinping Song, 4945-4955 Proviral DNA Synthesis in Infected Cells Christopher Aiken, and Didier Trono

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A Large Deletion in the Matrix Domain of the Human Michael Facke, Alfred Janetzko, 4972-4980 Immunodeficiency Virus gag Gene Redirects Virus Particle Robert L. Shoeman, and Assembly from the Plasma Membrane to the Endoplasmic Hans-Georg Krausslich Reticulum Human Cytomegalovirus Immediate-Early Gene 2 Protein Beth A. Furnari, Eric Poma, 4981-4991 Interacts with Itself and with Several Novel Cellular Timothy F. Kowalik, Shu-mei Proteins Huong, and Eng-Shang Huang of the Cyclin-Dependent Kinase Phosphorylation Ismail F. Moarefi, Don Small, Ilka 4992-5002 Site in Simian Virus 40 (SV40) Large T Antigen Specifically Gilbert, Matthias Hopfner, Sandra Blocks SV40 Origin DNA Unwinding K. Randall, Christine Schneider, Alicia A. R. Russo, Uwe Ramsperger, Avril K. Arthur, Hans Stahl, Thomas J. Kelly, and Ellen Fanning Multiple Binding Sites for Cellular Proteins in the 3' End Nathalie Pardigon, Edith Lenches, 5003-5011 of Sindbis Minus-Sense RNA and James H. Strauss Amplification Mediated by Polyomavirus Large T Antigen Luc St-Onge and Marcel Bastin 5025-5029 Defective in Replication Genetic Evidence that the Tat Proteins of Human Hal P. Bogerd, Robert A. Fridell, 5030-5034 Immunodeficiency Virus Types 1 and 2 Can Multimerize Wade S. Blair, and Bryan R. in the Eukaryotic Cell Nucleus Cullen Conserved Residues Pro-109 and Asp-116 Are Required for Meera Drelich, Markus Haenggi, 5041-5044 Interaction of the Human Immunodeficiency Virus Type 1 and Jan Mous Protein with Its Viral DNA Substrate Human Immunodeficiency Virus Type 1 Is an Frank Maldarelli, Mao-Yuan Chen, 5056-5061 Oligomeric Type I Integral Membrane Protein Ronald L. Willey, and Klaus Strebel The Signal for Translational Readthrough of a UGA Codon Guangpu Li and Charles M. Rice 5062-5067 in Sindbis Virus RNA Involves a Single Cytidine Residue Immediately Downstream of the Termination Codon Deletion of DNA Encoding the First Five Transmembrane Richard Longnecker, Cheryl L. 5068-5074 Domains of Epstein-Barr Virus Latent Membrane Proteins Miller, Blake Tomkinson, X-Qian 2A and 2B Miao, and Elliott Kieff VIRUS-CELL INTERACTIONS Nuclear Factor I and Epithelial Cell-Specific Transcription Doris Apt, Terence Chong, Yichun 4455-4463 of Human Papillomavirus Type 16 Liu, and Hans-Ulrich Bernard Involvement of Membrane-Bound Viral Glycoproteins in Filip P. Hanssens, Hans J. 4492-4496 Adhesion of Pseudorabies Virus-Infected Cells Nauwynck, and Maurice B. Pensaert Entry of Poliovirus into Cells Does Not Require a Low-pH Luis Perez and Luis Carrasco 4543-4548 Step ICP4, the Major Transcriptional Regulatory Protein of Colton A. Smith, Patricia Bates, 4676-4687 Herpes Simplex Virus Type 1, Forms a Tripartite Complex Ramon Rivera-Gonzalez, Baohua with TATA-Binding Protein and TFIIB Gu, and Neal A. DeLuca A Phenotypic Host Range Alteration Determines RD114 K. J. Dunn, C. C. Yuan, and 4704-4711 Virus Restriction in Feline Embryonic Cells D. G. Blair Primary Rat Cells Expressing a Hybrid James J. Manfredi and Carol 4750-4759 Polyomavirus-Simian Virus 40 Large T Antigen Prives Have Altered Growth Properties MxA-Dependent Inhibition of Virus Glycoprotein Jens-Jorg Schnorr, Sibylle 4760-4768 Synthesis in a Stably Transfected Human Monocytic Cell Schneider-Schaulies, Angela Line Simon-Jodicke, Jovan Pavlovic, Michel A. Horisberger, and Volker ter Meulen

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The Role of Vesicular Stomatitis Virus Matrix Protein in Brian L. Black, Richard B. 4814-4821 Inhibition of Host-Directed Gene Expression Is Genetically Rhodes, Margie McKenzie, Separable from Its Function in Virus Assembly and Douglas S. Lyles Nef from Primary Isolates of Human Immunodeficiency Stephen Anderson, Diane C. 4923-4931 Virus Type 1 Suppresses Surface CD4 Expression in Human Shugars, Ronald Swanstrom, and Mouse T Cells and J. Victor Garcia Regulation of the Cellular Thymidine Kinase Gene Promoter Holger H. Roehl, Michelle M. 4964-4971 in Simian Virus 40-Infected Cells Anderson, Christine S. Mehigh, and Susan E. Conrad TAR Loop-Dependent Human Immunodeficiency Virus trans Clyde E. Hart, Judith C. Galphin, 5020-5024 Activation Requires Factors Encoded on Human Mark A. Westhafer, and Gerald Chromosome 12 Schochetman A Mutation in VP4 Defines a New Step in the Late Stages of Nicola Moscufo, Alicia Gomez 5075-5078 Cell Entry by Poliovirus Yafal, Andrew Rogove, James Hogle, and Marie Chow

VIRAL AND CELLULAR The E5 Oncoprotein of Human Papillomavirus Type 16 Samuel W. Straight, Patricia M. 4521-4532 Transforms Fibroblasts and Effects the Downregulation of Hinkle, Richard J. Jewers, and the Epidermal Growth Factor Receptor in Keratinocytes Dennis J. McCance The EIA Products of Oncogenic Adenovirus Serotype 12 Hwei-Gene Heidi Wang, Peter 4804-4813 Include Amino-Terminally Modified Forms Able To Bind Yaciuk, Robert P. Ricciardi, the Protein but Not p300 Maurice Green, Kazushige Yokoyama, and Elizabeth Moran

BACTERIAL VIRUSES Protein-Primed DNA Replication: Role of Inverted Terminal Harri Savilahti and Dennis H. 4696-4703 Repeats in the Escherichia coli Bacteriophage PRD1 Life Bamford Cycle Location and Unusual Membrane Topology of the Immunity Meng-Ji Lu, York-Dieter Stierhof, 4905-4913 Protein of the Escherichia coli Phage T4 and Ulf Henning RNA Structure and Heterologous Recombination in the Shiroh Onodera, Xueying Qiao, 4914-4922 Double-Stranded RNA Bacteriophage +6 Paul Gottlieb, Jeffrey Strassman, Mikko Frilander, and Leonard Mindich

VIRAL PATHOGENESIS AND IMMUNITY Herpes Simplex Virus Pathogenesis in Transgenic Mice Is William J. Mitchell, Ronald J. De 4484- 4491 Altered by the Homeodomain Protein Hox 1.3 Santo, Shang-Ding Zhang, Ward F. Odenwald, and Heinz Arnheiter Fusion-Defective Mutants of Mouse Hepatitis Virus A59 James L. Gombold, Susan T. 4504-4512 Contain a Mutation in the Spike Protein Cleavage Signal Hingley, and Susan R. Weiss Multiplicity of Virus-Encoded Helper T-Cell Epitopes Michihiro Iwashiro, Tokukazu 4533-4542 Expressed on FBL-3 Tumor Cells Kondo, Takeyuki Shimizu, Hideo Yamagishi, Katsutoshi Takahashi, Yuji Matsubayashi, Tohru Masuda, Akira Otaka, Nobutaka Fujii, Akinori Ishimoto, Masaaki Miyazawa, Michael N. Robertson, Bruce Chesebro, and Kagemasa Kuribayashi Viral Determinants That Control the Neuropathogenicity of Michiaki Masuda, Paul M. 4580-4587 PVC-211 Murine Leukemia Virus In Vivo Determine Brain Hoffman, and Sandra K. Ruscetti Capillary Endothelial Cell Tropism of the Virus In Vitro

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Viral Determinants of Age-Dependent Virulence of Sindbis Pamela C. Tucker, Ellen G. 4605-4610 Virus for Mice Strauss, Richard J. Kuhn, James H. Strauss, and Diane E. Griffin A Mutation in the RNA Polymerase of Poliovirus Type 1 Maryse Tardy-Panit, Bruno 4630-4638 Contributes to Attenuation in Mice Blondel, Annette Martin, Fredj Tekaia, Florian Horaud, and Francis Delpeyroux Identification of a Linear Neutralization Site within the Stefania Lombardi, Carlo Garzelli, 4742-4749 Third Variable Region of the Feline Immunodeficiency Corinna La Rosa, Lucia Zaccaro, Virus Envelope Steven Specter, Gino Malvaldi, Franco Tozzini, Fulvio Esposito, and Mauro Bendinelli Induction of Interleukin-8 Gene Expression Is Associated John E. Oakes, Carlos A. 4777-4784 with Herpes Simplex Virus Infection of Human Corneal Monteiro, Christopher L. Cubitt, Keratocytes but Not Human Corneal Epithelial Cells and Robert N. Lausch Identification of a Single Amino Acid Residue in the Michele Caggana, Perry Chan, and 4797-4803 Protein VP1 of Coxsackievirus B4 That Determines the Arlene Ramsingh Virulent Phenotype Characterization of Neutralizing Monoclonal Antibodies to J. A. McKeating, C. Shotton, J. 4932-4944 Linear and Conformation-Dependent Epitopes within the Cordell, S. Graham, P. Balfe, N. First and Second Variable Domains of Human Sullivan, M. Charles, M. Page, A. Immunodeficiency Virus Type 1 gpl20 Bolmstedt, S. Olofsson, S. C. Kayman, Z. Wu, A. Pinter, C. Dean, J. Sodroski, and R. A. Weiss Chimeric Tick-Borne Encephalitis and Dengue Type 4 Alexander G. Pletnev, Michael 4956-4963 Viruses: Effects of on Neurovirulence in Mice Bray, and Ching-Juh Lai In Vivo Role of Lymphocyte Subpopulations in the Control G. Oldham, J. C. Bridger, C. J. 5012-5019 of Virus Excretion and Mucosal Antibody Responses of Howard, and K. R. Parsons Cattle Infected with Rotavirus Differential Activation of Human Immunodeficiency Virus Mark C. Hannibal, David M. 5035-5040 Type 1 and 2 Transcription by Specific T-Cell Activation Markovitz, Nina Clark, and Signals Gary J. Nabel Molecular Cloning of Infectious Ecotropic Murine Leukemia Hillary D. White, William R. 5045-5050 V'irus AK7 from an emv-14-Positive AKXL-5 Mouse and the Green, and Nuria R. Gine Resistance of AK7 to Recognition by Cytotoxic T Lymphocytes Isolation and Characterization of New Wild-Type Isolates of David L. Suarez, Martin J. 5051-5055 Bovine Lentivirus VanDerMaaten, Charles Wood, and Cecelia A. Whetstone