Posters A-Z

Ali, Mehreen Systematic modeling of pan-cancer drug responses using Bayesian 26 multi-source regression

Avican, Kemal PATHOGENEX: Human bacterial pathogen expression database 27

Bao, Jie SOX9 is selectively required for adenocarcinoma progression in 28 non-small cell lung cancer histopathologies

Barandun, Jonas Evolutionary compaction and adaptation visualized by the structure of 29 the dormant microsporidian ribosome

Bauer, Moritz Rapid reactivation of the inactive X in a novel iPSC system 30

Belova, Tatiana Annotation and mapping of encoding allergenicity in 31 wheat

Caglayan, Safak A human embryonic stem cell model of optic atrophy 1 deficiency 32 reveals the mitochondrial homeostasis as a regulator of neuronal differentiation

Castro-Mondragon, Jaime Combining transcriptional and post-transcriptional regulation to predict 33 mutations altering the gene regulatory program in cancer cells

Chotiwan, Nunya Whole tissue Ex Vivo Imaging Sheds Light on Tropism and 34 Neuroinvasion of Tick-borne Flavivirus in mouse brain

Christiansen, Line Marie Neo1, the essential lipid flippase? 35

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Cieslar-Pobuda, Artur DNMT3B deficiency alters mitochondrial biogenesis and a-ketoglutarate 36 levels in human embryonic stem cells

Cunha, Eva Cryo EM Structure of Helicobacter pylori inhibitor-bound urease at 2.3 Å 37 resolution del Peso-Santos, Teresa Presenter: Bala, Anju Understanding biofilm related regulatory networks in Vibrio cholerae 38

Denham, Mark Identifying genetic risk variants for Parkinson’s Disease 39

Dyla, Mateusz Kinase signaling complexes: The effect of linkers on tethered 40 catalysis el Azhar, Yasmine Signalling dynamics in the developing neural tube 41

Esguerra, Camila New insights into the early mechanisms underlying epileptogenesis in a 42 zebrafish model of Dravet syndrome

Fu, Yu Incomplete X inactivation is reflected in complex trait 43 genetic architecture

García, Laura Does chromatin metabolism drive breast cancer evolution? 44

Goradia, Nishit Bharat RAI2-induced polymerization regulates corepressor activity of 45 tumorigenic CtBP proteins

Gulyas-Onodi, Zsofia Inflammasome activation in end-stage failing heart 46

Gutierrez-Fernandez, Javier Reactivation of p53 tumor suppressor function 47

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Haapaniemi, Emma Presenter: Soppa, Inkeri Targeted CRISPR editing to S cell cycle phase 48

Hassan, Shabbeer No effects of high resolution population-specific genetic map on 49 downstream genomic analyses

Hautakangas, Heidi A genome-wide meta-analysis of migraine with over 102,000 cases 50 identifies 124 risk loci

Henriksson, Johan Inferring mechanism from high-throughput data - CD4 T cells 51

Hermjakob, Henning Reactome pathway analysis and visualization 52

Hernandez Alias, Xavier Translation efficiency across healthy and tumor tissues is 53 proliferation-dependant

Hsieh, Ping-Han Correlation adjustment to improve the modeling of association-based 54 networks

Ivanova, Maria Systematic characterisation of the role of exported proteins in malaria 55 parasite-host interactions

Jann, Cosimo Dissecting the heat shock response in yeast by CRISPRi 56

Kowalski, Antoni Alpha-synuclein is a novel activator of the plasma membrane calcium 57 ATPase

Kumar, Rajender Genomic diversity of the genus Francisella and associated pathogenicity 58 island

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Lafita, Aleix The role of protein domain repeat stalks in bacterial surface adhesins 59

Lang, Benjamin Beyond the peaks: A better processing method for eCLIP protein–RNA 60 interaction data?

Langenbach, Dorothee What are the cellular and molecular targets of extracellular ATP, a key 61 pro-inflammatory signal during intestinal infection?

Lundgren, Sara Epigenetic aging in BMI-discordant monozygotic twin pairs 62

Malyutina, Alina Drug combination sensitivity scoring facilitates the discovery of 63 synergistic and efficacious drug combinations in cancer

Mereu, Elisabetta Benchmarking Single-Cell RNA Sequencing Protocols for Cell Atlas 64 Projects

Mohammadi, Nasibeh The role of Guanylate-Binding Proteins (GBPs) during intracellular 65 infection with Francisella tularensis

Muraleedharan, Samada A defensive host cell death program that is actively suppressed by the 66 intracellular pathogen Chlamydia trachomatis

Neguembor, Maria Victoria Investigating the role of transcription in 3D genome folding and loop 67 extrusion

Nissen, Josephine Dannersø Investigating the ultrastructure of the axon initial segment by 68 cryo-electron tomography

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Ovesen, Peter Deficiency for the neurexin-receptor SorCS1 impairs synaptic plasticity, 69 alters GABAA receptor expression and causes autism-like behavior

Pardo Lorente, Natalia Integration of genome-wide PAX8 and HNF1B binding with 70 transcriptomics to deconvolute their contribution in clear cell renal carcinoma

Abstract cancelled 71

Rogalska, Malgorzata Ewa Self-regulatory network of the core spliceosome 72

Rosendal, Ebba Viperin restricts Zika virus and tick-borne encephalitis virus replication 73 by targeting NS3 for proteasomal degradation

Saad, Joseph FLT3 Activating Mutations Confer Significant Sensitivity to BET Inhibition 74 in AML

Saarentaus, Elmo Most rare and high-risk CNV carriers do not have major health, 75 cognitive or socioeconomic consequences

Salasova, Alena The proneurotrophin receptor SorCS2 is a novel regulator of Wnt/PCP 76 pathway during embryogenesis and midbrain development

Sandblad, Linda Presenter: Söderholm, Niklas Novel Streptomyces growth morphology alters the metabolome and 77 promotes antimicrobial activity

Sayers, Claire Designing a systematic screen for fertility genes in Plasmodium berghei 78

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Schröder, Björn O. Impaired colonic mucus barrier in genetically obese mice 79

Sevillano-Quispe, Oscar G Structural dynamics of glutamate NMDA receptors 80

Sharma, Atin Identification of novel determinants of intracellular adaptation in Shigella 81 flexneri

Sinha, Vishal Variants in regulatory elements of PDE4D associate with major mental 82 illness in the Finnish population

Sixt, Barbara The Chlamydia inclusion membrane protein CpoS recruits Rab GTPases 83 to subvert the host cellular surveillance system

Subramani, Saranya Identification of the magnesium-sensing region in Esherichia coli MgtA 84

Takeuchi, Tomonori Presenter: Henningsen, Kim Memory consolidation, dopamine and two distinct novelty systems 85

Thomasen, Pernille B. SorCS2: A novel progranulin receptor and regulator of motor neuron 86 outgrowth

Tynell, Janne Analyzing the cellular interactomes of the hantavirus N and NSs proteins 87

Uckelmann, Michael Swipe right for DNA repair - Target selection of two epigenetic modifiers 88

Urpa, Lea Genetic architecture of intellectual disability in Northern Finland 89

Page 16 Posters A-Z van der Ent, Wietske Toward novel therapeutic interventions for SNARE complex pathologies 90

Vereb, Zoltan Immunological properties of adipose tissue derived mesenchymal stem 91 cells under inflammatory conditions

Vielfort, Katarina Presenters: Bergström, Sven; Vielfort, Katarina Development of antibacterial compounds against Chlamydia 92 trachomatis

Wang, Tianduanyi Target deconvolution to understand cellular drug responses 93

Wang, Wenyu Combined gene essentiality scoring improves the prediction of cancer 94 dependency map

Wang, Yinyin Revisiting the concept of Meridian in Chinese Traditional Medicine using 95 machine learning approaches

Wilmanns, Matthias A cidal toxin/antitoxin pair from Mycobacterium tuberculosis: A suitable 96 drug target?

Xing, Mengtan Genetic interaction between non-homologous end joining factors in 97 mice and humans

Zagidullin, Bulat DrugComb: An integrative cancer drug combination data portal 98

Zerbino, Daniel Functional annotation of GWAS regulatory variants powered by Ensembl 99

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