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Research Integrity Fairness Honesty Accountability Stewardship Stewardship Honesty Fairness ISSUE36 SUMMER 2017 Long-Term Fellows and Young Investigators Collaborative communities in the making PAGE HONESTY STEWARDSHIPS 10 – 11 FAIRNESS ACCOUNTABILITY RESEARCH INTEGRITY FAIRNESS HONESTY ACCOUNTABILITY STEWARDSHIP STEWARDSHIP HONESTY FAIRNESS ACCOUNTABILITY RESEARCH RESEARCH INTEGRITY INTEGRITY Ido Amit Alberto Bardelli Ralf Bartenschlager Genomic and epigenomic Precision oncology, cancer Cell biology of virus control of the immune system genomics replication HONESTY RESEARCH INTEGRITY Rehovot, Israel Turin, Italy Heidelberg, Germany FAIRNESS Responsible research conduct STEWARDSHIP EMBO launchesFAIRNESS research HONESTY ACCOUNTABILITY Lena Claesson-Welsh Monica M.G. Di Luca Mina J. Bissell* Frances M. Brodsky Damian Brunner Piero Carninci* and Blood vessels in physiology Synapse biology in Microenvironment and Clathrin-mediated Cell morphogenesis Transcription regulation and disease health and diseases tissue architecture Zurich, Switzerland lncRNA function Yokohama, Japan Uppsala, Sweden Milan, Italy STEWARDSHIP ACCOUNTABILITYintegrity workshops Berkeley, United States London, United Kingdom RESEARCH PAGE 3 Daniel W. Gerlich Isabel Gordo Stephan Grill Jeremy Farrar Martin Fussenegger Fátima Gebauer Hernández Niko Geldner EMBO Gold Medal Assembly and function of the Bacterial adaptation within Physics of Life Infectious diseases and Engineering cells for Regulation of mRNA Polarised epithelia cell division machinery ecosystems Dresden, Germany global health therapeutic applications translation and cancer formation in plants Lausanne, Switzerland Vienna, Austria Oeiras, Portugal Maya Schuldiner receives award London, United Kingdom Basel, Switzerland Barcelona, Spain INTEGRITY 65 life scientists elected for protein research Meet the new EMBO PAGE 7 Saulius Klimašauskas Claudia Köhler Roman Jerala Johanna Joyce Gerard Karsenty* Roy Kishony Thomas Klausberger Mechanisms and engineering of Epigenetic regulation of Synthetic biology and Exploring and exploiting the Skeletal biology Evolution of antibiotic New kids on the block DNA methylases plant speciation molecular immunology Memberstumour microenvironment New York, United States resistance for cognition Vienna, Austria Vilnius, Lithuania Uppsala, Sweden How neuroscientists explore Ljubljana, Slovenia Lausanne, Switzerland Haifa, Israel alternative model organisms PAGES 4-6 PAGE 8-9 Sten Linnarsson Jennifer Lippincott-Schwartz* Núria López-Bigas Susanne Mandrup Single-cell biology of the Imaging subcellular Mutational processes Transcriptional networks nervous system organization and dynamics leading to carcinogenesis regulating metabolism ERC anniversary Odense, Denmark Stockholm, Sweden Ashburn, United States Barcelona, Spain EMBO Members reflect on ten years of support for ambitious projects PAGE 13 Panayiota Poirazi Dissecting the role of dendrites in memory Heraklion Greece www.embo.org Table of contents HONESTY STEWARDSHIP EMBO news FAIRNESS ACCOUNTABILITYScience story RESEARCH INTEGRITY FAIRNESS HONESTY ACCOUNTABILITY STEWARDSHIP STEWARDSHIP HONESTY FAIRNESS ACCOUNTABILITY RESEARCH RESEARCH INTEGRITY INTEGRITY FAIRNESS HONESTY RESEARCH INTEGRITY STEWARDSHIP FAIRNESS HONESTY ACCOUNTABILITY STEWARDSHIP EMBO NEWS ACCOUNTABILITY RESEARCH SCIENCE STORY INTEGRITYEMBO introduces research integrity EMBL Photolab Marietta Schupp, © workshops Page 3 New model organisms: neuroscience branches out Editorial Welcoming 65 new EMBO Pages 8 – 9 Members Pages 4 – 6 he most famous guideline for ethical Science policy professional behaviour is probably Easy submission at EMBO Press Page 6 Tthe Hippocratic Oath. While it is no longer used in its original form, it has been Word Conference on Research Integrity: a supplanted by more modern ethical codes roundup Page 12 for the medical profession. In the sciences, we are still a long way off from having a How should universities and editors work universally accepted and adopted code of together? Page 12 research conduct. Of course this does not mean that, on the whole, we don’t carry out our research in a thoughtful and reliable way. But unfor- EMBO community tunately, ethical rules are too frequently EMBO NEWS breached within our profession, not just in Updates from across Maya Schuldiner receives EMBO Gold the shape of high-profile misconduct cases, Europe Pages 14 – 16 but also as small, often perhaps uninten- Medal Page 7 tional, mistakes. Analysis at the EMBO Press publications and other journals has shown that nearly 20% of manuscripts Awards and publications include such mistakes, for example in the presentation of figures. Achievements and papers by members of I am convinced that many of them are the EMBO community Page 17 the result of a lack of awareness. It might not be immediately obvious, for example, that formulating a hypothesis after the EMBO events results are known (“HARKing”) could be seen as a form of misconduct. Upcoming courses, workshops and EMBO is responding to this need for training in the life science community EMBO NEWS conferences Page 18 (see p3 and p12). For example, through its Fellows and Young Investigators on the research integrity workshops, EMBO offers scientists across Europe an efficient way value of the EMBO community Pages Fresh from EMBO press of learning about broadly accepted rules 10 – 11 for responsible research conduct and to Some of EMBO’s latest publications at a share their experience and lessons learnt. Marking the 10th anniversary of the glance Page 19 Feedback from the five pilot sessions has ERC Page 13 shown that they can act as catalysts for concrete actions at an institutional level. Integrating responsible research more firm- ly across the European life sciences will take a collective effort from our communi- ty. Seeing the change that is already taking place, I look forward to continuing this work for and with the EMBO community. Maria Leptin Director, EMBO 2 EMBOencounters | Summer 2017 | [email protected] ©2017 EMBO EMBO NEWS HONESTY STEWARDSHIP FAIRNESS ACCOUNTABILITY RESEARCH INTEGRITY FAIRNESS HONESTY ACCOUNTABILITY STEWARDSHIP STEWARDSHIP HONESTY FAIRNESS ACCOUNTABILITY RESEARCH RESEARCH INTEGRITY INTEGRITY The ins andFAIRNESS outs HONESTY RESEARCH INTEGRITY of responsible STEWARDSHIP FAIRNESS research conduct HONESTY ACCOUNTABILITY STEWARDSHIP EMBO introduces research integrity ACCOUNTABILITY workshops RESEARCH onesty, accountability, professional cour- “The feedback we received during the pilot code of conduct for mentorship. In Porto, a tesy and fairness,INTEGRITY and good stewardship sessions was overwhelmingly positive,” says working group to develop authorship guidelines H– according to the Singapore Statement of EMBO Science Policy Programme Officer Sandra for the i3S was set up by the institute’s Director, Research Integrity, these are the four fundamen- Bendiscioli, who organizes the workshops in Mario Barbosa. tal principles of responsible research. collaboration with EMBO Members at the host EMBO contributed to the creation of this docu- institutes. Working with the community ment during the World Conference on Research The discussions highlighted a general lack The research integrity workshops form part Integrity in Singapore. “Committing these prin- of awareness of inappropriate lab practices and of EMBO’s activities on responsible research ciples to paper, was an important step in the their consequences for the participants – mostly conduct. EMBO already requires all scien- right direction. Next, it is important to support senior post-docs and early-career group leaders. tists funded through its Long-Term Fellowship researchers in embedding them in their everyday More importantly, according to Bendiscioli, “the Programme to complete an online training course work,” says EMBO Science Policy Programme sessions showed us that there was great appe- on research integrity*. In addition, all four EMBO Manager Michele Garfinkel. tite for discussing dilemmas and uncertainties Press publications have put in place specific poli- That is why EMBO initiated a set of pilot in scientific research, and for putting in place cies with the aim of fostering responsible research workshops to raise awareness of research integ- structures or processes to foster good research and reporting practices. rity issues and encourage responsible research practices.” The sessions are organized and delivered practices among life scientists in Europe. The by the EMBO Science Policy Programme in sessions introduce the values of responsible From awareness to actions close collaboration with an EMBO Member at research, explain internationally accepted defini- One of the participants in the workshop at the host institutes in EMBC Member States. Those tions of misconduct and highlight questionable Spanish National Centre of Biotechnology in members interested in co-organizing a work- research practices. Misconduct cases that have Madrid said it encouraged her “to think a lot shop at their institute are welcome to contact the been discussed publicly are used to illustrate about my behaviour in the lab, and I am going to Science Policy Programme ([email protected]) to the importance of honouring the principles of propose a talk here in my building about research express their interest in a future workshop or find responsible research. integrity.” Senior researchers at the Curie out more information. Institute in Paris went a step further and decided Pilot success to provide compulsory training in research integ- * EMBO was involved in the development of the Following a pilot run of five
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