Neuroscience Task Force Report
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Rhythms of the Brain
Rhythms of the Brain György Buzsáki OXFORD UNIVERSITY PRESS Rhythms of the Brain This page intentionally left blank Rhythms of the Brain György Buzsáki 1 2006 3 Oxford University Press, Inc., publishes works that further Oxford University’s objective of excellence in research, scholarship, and education. Oxford New York Auckland Cape Town Dar es Salaam Hong Kong Karachi Kuala Lumpur Madrid Melbourne Mexico City Nairobi New Delhi Shanghai Taipei Toronto With offices in Argentina Austria Brazil Chile Czech Republic France Greece Guatemala Hungary Italy Japan Poland Portugal Singapore South Korea Switzerland Thailand Turkey Ukraine Vietnam Copyright © 2006 by Oxford University Press, Inc. Published by Oxford University Press, Inc. 198 Madison Avenue, New York, New York 10016 www.oup.com Oxford is a registered trademark of Oxford University Press All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior permission of Oxford University Press. Library of Congress Cataloging-in-Publication Data Buzsáki, G. Rhythms of the brain / György Buzsáki. p. cm. Includes bibliographical references and index. ISBN-13 978-0-19-530106-9 ISBN 0-19-530106-4 1. Brain—Physiology. 2. Oscillations. 3. Biological rhythms. [DNLM: 1. Brain—physiology. 2. Cortical Synchronization. 3. Periodicity. WL 300 B992r 2006] I. Title. QP376.B88 2006 612.8'2—dc22 2006003082 987654321 Printed in the United States of America on acid-free paper To my loved ones. This page intentionally left blank Prelude If the brain were simple enough for us to understand it, we would be too sim- ple to understand it. -
The Creation of Neuroscience
The Creation of Neuroscience The Society for Neuroscience and the Quest for Disciplinary Unity 1969-1995 Introduction rom the molecular biology of a single neuron to the breathtakingly complex circuitry of the entire human nervous system, our understanding of the brain and how it works has undergone radical F changes over the past century. These advances have brought us tantalizingly closer to genu- inely mechanistic and scientifically rigorous explanations of how the brain’s roughly 100 billion neurons, interacting through trillions of synaptic connections, function both as single units and as larger ensem- bles. The professional field of neuroscience, in keeping pace with these important scientific develop- ments, has dramatically reshaped the organization of biological sciences across the globe over the last 50 years. Much like physics during its dominant era in the 1950s and 1960s, neuroscience has become the leading scientific discipline with regard to funding, numbers of scientists, and numbers of trainees. Furthermore, neuroscience as fact, explanation, and myth has just as dramatically redrawn our cultural landscape and redefined how Western popular culture understands who we are as individuals. In the 1950s, especially in the United States, Freud and his successors stood at the center of all cultural expla- nations for psychological suffering. In the new millennium, we perceive such suffering as erupting no longer from a repressed unconscious but, instead, from a pathophysiology rooted in and caused by brain abnormalities and dysfunctions. Indeed, the normal as well as the pathological have become thoroughly neurobiological in the last several decades. In the process, entirely new vistas have opened up in fields ranging from neuroeconomics and neurophilosophy to consumer products, as exemplified by an entire line of soft drinks advertised as offering “neuro” benefits. -
Tor Wager Diana L
Tor Wager Diana L. Taylor Distinguished Professor of Psychological and Brain Sciences Dartmouth College Email: [email protected] https://wagerlab.colorado.edu Last Updated: July, 2019 Executive summary ● Appointments: Faculty since 2004, starting as Assistant Professor at Columbia University. Associate Professor in 2009, moved to University of Colorado, Boulder in 2010; Professor since 2014. 2019-Present: Diana L. Taylor Distinguished Professor of Psychological and Brain Sciences at Dartmouth College. ● Publications: 240 publications with >50,000 total citations (Google Scholar), 11 papers cited over 1000 times. H-index = 79. Journals include Science, Nature, New England Journal of Medicine, Nature Neuroscience, Neuron, Nature Methods, PNAS, Psychological Science, PLoS Biology, Trends in Cognitive Sciences, Nature Reviews Neuroscience, Nature Reviews Neurology, Nature Medicine, Journal of Neuroscience. ● Funding: Currently principal investigator on 3 NIH R01s, and co-investigator on other collaborative grants. Past funding sources include NIH, NSF, Army Research Institute, Templeton Foundation, DoD. P.I. on 4 R01s, 1 R21, 1 RC1, 1 NSF. ● Awards: Awards include NSF Graduate Fellowship, MacLean Award from American Psychosomatic Society, Colorado Faculty Research Award, “Rising Star” from American Psychological Society, Cognitive Neuroscience Society Young Investigator Award, Web of Science “Highly Cited Researcher”, Fellow of American Psychological Society. Two patents on research products. ● Outreach: >300 invited talks at universities/international conferences since 2005. Invited talks in Psychology, Neuroscience, Cognitive Science, Psychiatry, Neurology, Anesthesiology, Radiology, Medical Anthropology, Marketing, and others. Media outreach: Featured in New York Times, The Economist, NPR (Science Friday and Radiolab), CBS Evening News, PBS special on healing, BBC, BBC Horizons, Fox News, 60 Minutes, others. -
How Big Is Human Memory, Or on Being Just Useful Enough
Downloaded from learnmem.cshlp.org on September 29, 2021 - Published by Cold Spring Harbor Laboratory Press REVIEW Yadin Dudai How Big Is Human Memory, Department of Neur0bi010gy or On Being Just Useful Enough The Weizmann Institute of Science Reh0v0t 76100 Israel We are, in many respects, what we remember. But how much do we do? So far, science has provided only a very partial answer to this riddle. The magical number seven, plus or minus two, seems to constrain the capacity of our immediate memory (Miller 1956). But surely its constraints dissipate when memories settle in long-term stores. Yet how big are these stores? If we combine all of our factual knowledge and personal reminiscence, childhood scenes and memories of the past day, intimate experiences and professional expertisemhow many items are there, that, combined together, mold us into unique individuals? The answer is not simple, and neither is the question. For example, what is an item in long-term memory? And how can we measure it, being sure that we unveil memory capacity and not merely the occasional ability to tap it? Such theoretical and practical difficulties, no doubt, have contributed to the fact that the capacity of human memory is still an enigma. Yet, despite the inherent and undeniable complexities, the issue deserves to be retrieved, once in a while, from the oblivions of the collective memory of the scientific community. (For a selection of earlier discussions of the size of human long-term memory, see Galton 1879; Landauer 1986; Crovitz et al. 1991.) Folk Psychology and When confronted with the issue, many tend to provide an intuitive Early Views estimate of the size of their memory, based either on belief or introspection or both. -
Making Your Mind: Molecules, Motion, and Memory Lecture One – Mapping Memory in the Brain Eric R
Making Your Mind: Molecules, Motion, and Memory Lecture One – Mapping Memory in the Brain Eric R. Kandel, M.D. 1. Start of Lecture I (0:15) [ANNOUNCER:] From the Howard Hughes Medical Institute. The 2008 Holiday Lectures on Science. This year's lectures, "Making Your Mind: Molecules, Motion, and Memory," will be given by Dr. Eric Kandel, Howard Hughes Medical Institute investigator at Columbia University, and Dr. Thomas Jessell, Howard Hughes Medical Institute investigator also at Columbia University. The first lecture is titled "Mapping Memory in the Brain." And now to introduce our program, the President of the Howard Hughes Medical Institute, Dr. Thomas Cech. 2. Welcome by HHMI President Dr. Thomas Cech (1:08) [DR. CECH] Welcome to the Howard Hughes Medical Institute and the 2008 Holiday Lectures on Science. The Institute initiated this series in 1993. In 1995 I had the pleasure of coming here and delivering the lectures on catalytic RNA, and since I've been President of the Institute it's been a great pleasure to be involved in choosing 18 terrific scientists to talk to students here in the auditorium. The Holiday Lectures are one of more than 30 research and education programs of the Institute and please visit our website www.hhmi.org to learn more about all of our activities. This lecture series focuses on the most complex organ in our body and arguably the one that most is responsible for making us human. Clearly without this organ you wouldn't be able to find this auditorium, and even if you got here you wouldn't understand a word that was being said. -
Meeting Program SID 2019 ANNUAL MEETING
Meeting Program SID 2019 ANNUAL MEETING 2019 Annual Meeting Scientific 2019 Annual Meeting Program Chairs, Committee Committee on Education Members, and Reviewers Chairs and Committee CHAIRS Members Dan Kaplan, MD/PhD, University of Pittsburgh CHAIRS Ethan Lerner, MD/PhD, Mass General Hospital Heidi Kong, MD, National Insitutes of Health Todd Ridky, MD/PhD, University of Pennsylvania COMMITTEE MEMBERS Lloyd Miller, MD/PhD, Johns Hopkins University COMMITTEE MEMBERS Kevin Wang, MD/PhD, Stanford University My Mahoney, PhD, Thomas Jefferson University Spiro Getsios, PhD, Aspect Biosystems Alexander Marneros, MD/PhD, Harvard University Peggy Myung, MD/PhD, Yale University Robert Dellavalle, MD/PhD, University of Colorado Marjana Tomic-Canic PhD, University of Miami Amanda MacLeod, MD, Duke University Vladimir Botchkarev, MD/PhD, Boston University Cristina de Guzman Strong, PhD, Washington University-St. Louis Tissa Hata, MD, University of California, San Diego Maryam Asgari, MD, Massachusetts General Hospital Ken Tsai, MD/PhD, Moffitt Cancer Center and Paul Nghiem, MD/PhD, University of Washington Research Institute Richard Granstein, MD, Weill Cornell Medical School Sarah Millar, PhD, Mt. Sinai Medical School Matthew Vesley, MD/PhD, Yale University REVIEWERS Anna Di Nardo, MD/PhD Jennifer Gill, MD/PhD, University of Texas Southwestern Carolyn Lee, MD/PhD Jonathan Silverberg, MD/PhD ACKNOWLEDGEMENTS Bogi Andersen, MD The organizers of the 2019 SID Annual Meeting gratefully Kavita Sarin, MD/PhD acknowledge the sponsors, exhibitors, and participants whose Peter Koch, PhD Tiffany C. Scharschmidt, MD attendance has helped to make this meeting possible. Joseph Merola, MD Sakeen Kashem, MD/PhD Thomas Hultsch, MD Amanda MacLeod, MD Liang Deng, MD/PhD Ya-Chieh Hsu, PhD Crystal Aguh, MD Katherine Radek, PhD Paul Nghiem, MD/PhD Alicia Mathers, PhD Raymond Cho, MD Zelma Chiesa, MD Anna Mandinova, MD/PhD Brian Capell, MD/PhD Ryan R. -
Dynamics of Excitatory-Inhibitory Neuronal Networks With
I (X;Y) = S(X) - S(X|Y) in c ≈ p + N r V(t) = V 0 + ∫ dτZ 1(τ)I(t-τ) P(N) = 1 V= R I N! λ N e -λ www.cosyne.org R j = R = P( Ψ, υ) + Mγ (Ψ, υ) σ n D +∑ j n k D k n MAIN MEETING Salt Lake City, UT Feb 27 - Mar 2 ................................................................................................................................................................................................................. Program Summary Thursday, 27 February 4:00 pm Registration opens 5:30 pm Welcome reception 6:20 pm Opening remarks 6:30 pm Session 1: Keynote Invited speaker: Thomas Jessell 7:30 pm Poster Session I Friday, 28 February 7:30 am Breakfast 8:30 am Session 2: Circuits I: From wiring to function Invited speaker: Thomas Mrsic-Flogel; 3 accepted talks 10:30 am Session 3: Circuits II: Population recording Invited speaker: Elad Schneidman; 3 accepted talks 12:00 pm Lunch break 2:00 pm Session 4: Circuits III: Network models 5 accepted talks 3:45 pm Session 5: Navigation: From phenomenon to mechanism Invited speakers: Nachum Ulanovsky, Jeffrey Magee; 1 accepted talk 5:30 pm Dinner break 7:30 pm Poster Session II Saturday, 1 March 7:30 am Breakfast 8:30 am Session 6: Behavior I: Dissecting innate movement Invited speaker: Hopi Hoekstra; 3 accepted talks 10:30 am Session 7: Behavior II: Motor learning Invited speaker: Rui Costa; 2 accepted talks 11:45 am Lunch break 2:00 pm Session 8: Behavior III: Motor performance Invited speaker: John Krakauer; 2 accepted talks 3:45 pm Session 9: Reward: Learning and prediction Invited speaker: Yael -
Report to the Internal Review Committee
Center for Neuroscience & Society University of Pennsylvania REPORT TO THE INTERNAL REVIEW COMMITTEE I. Mission …………………………………………………………………………………….…………………….. p. 2 II. History …………………………………………………………………………………………………….…….. p. 2 III. People ………………………………………………………………………………………………………….. p. 2 Faculty Staff Fellows Visiting Scholars Advisory Board IV. Funding …………………………………………………………………………………………………….…… p. 4 V. Space and Facilities ………………………………………………………………………………………… p. 4 VI. Overview .……………………………………………………………………………………………………… p. 5 VII. Research on Neuroscience and Society…………………………………………………………. P. 5 VIII. Outreach (Including K-12 Education) …………………………………………………………… p. 7 Online Public Talks Academic Outreach Within Penn Outreach Beyond Penn Conferences K-12 Education IX. Higher Education ………………………………………………………………………………………….. p. 11 Neuroscience Boot Camp Continuing Medical Education Neuroethics Learning Collaborative Penn Fellowships in Neuroscience and Society New Courses Preceptorials Graduate Certificate in Social, Cognitive and Affective Neuroscience (SCAN) X. Conclusions, Challenges for the Future …………………………………………………………… p. 15 Appendices 1-11 Submitted April 9, 2016, by Martha J. Farah, Director of the Center for Neuroscience & Society 1 I. Mission Neuroscience is giving us increasingly powerful methods for understanding, predicting and manipulating the human mind. Every sphere of life in which psychology plays a central role – from education and family life to law and politics – will be touched by these advances, and some will be profoundly transformed. -
Stephanie Bugden Curriculum Vitae (Pdf)
Stephanie Bugden, Ph.D. Postdoctoral Fellow email: [email protected] Department of Psychology Phone number: (919) 884-9870 The University of Pennsylvania 425 S. University Ave, Philadelphia, PA, 19104 Education and Training Postdoctoral Fellow, March 2015 – Present Duke University (Mar 2015-Aug 2015) & The University of Pennsylvania Supervisor: Dr. Elizabeth M. Brannon The University of Western Ontario, December, 2014 Ph.D., Psychology Supervisor: Dr. Daniel Ansari Thesis Title: Characterizing persistent developmental dyscalculia: A cognitive neuroscience approach The University of Western Ontario, August, 2010 M.Ed., Special Education and Educational Psychology Supervisor: Dr. Daniel Ansari The University of Western Ontario, April, 2008 B.A., Honors in Psychology, Developmental & Educational, Minor in French Publications Google Scholar Citations (as of September 10, 2018): 353, h-index: 5 (i10-index: 5) † reviews, chapters, commentaries †Dresler, T., Bugden, S., Gouet, C., Lallier, M., Oliveira, D., Pinheiro-Chagas, P., Pires, A., Want, Y., Zugarramudi, C., & Weissheimer, J. (2018). A translational framework of educational neuroscience in learning disorders. Frontiers in Integrative Neuroscience, 12:25, doi: 10.3389/fnint.2018.00025. Lyons, I.M., Bugden, S., Zhang, S., De Jesus, S., & Ansari, D. (2018). Symbolic number skills predict growth in nonsymbolic number skills in kindergarteners. Developmental Psychology, 5(3), 440-457. †Bugden, S., DeWind, N., & Brannon, E. M. (2016). Using cognitive training to unravel the mechanistic link between the approximate number system and symbolic math skills, Current Opinions in Behavioral Sciences, 10, 73-80. doi: 10.1016/j.cobeha.2016.05.002. Bugden, S., & Ansari, D. (2016). Probing the nature of deficits in the ‘Approximate Number System’ in children with persistent Developmental Dyscalculia. -
Blaming the Brain
Minnesota Journal of Law, Science & Technology Volume 11 Issue 1 Article 5 2010 Blaming the Brain Steven K. Erickson Follow this and additional works at: https://scholarship.law.umn.edu/mjlst Recommended Citation Steven K. Erickson, Blaming the Brain, 11 MINN. J.L. SCI. & TECH. 27 (2010). Available at: https://scholarship.law.umn.edu/mjlst/vol11/iss1/5 The Minnesota Journal of Law, Science & Technology is published by the University of Minnesota Libraries Publishing. ERICKSON SK. Blaming the Brain. MINN. J.L. SCI. & TECH. 2010;11(1):27-77. Blaming the Brain Steven K. Erickson* I. Introduction ............................................................................ 27 II. The Birth of Neurolaw .......................................................... 34 A. Brains Without Minds ................................................ 36 B. The Way of Cognitive Neuroscience ........................... 42 1. Reduction and Deduction ..................................... 46 2. The Life of the Brain ............................................. 50 III. Neurolaw’s Secret Ambition ................................................ 55 A. Making the Criminal, Civil ......................................... 57 B. Rise of the Control Tests ............................................. 65 C. Abolition of Agency ..................................................... 73 IV. Conclusion ............................................................................ 76 I. INTRODUCTION People are more than their brains. Legal and social traditions have long held people -
Strategic Plan 2015
NS Strategic Plan 2015 Strategic Plan Creation of a Neuroscience Institute at UMass Amherst 1. Vision p3 2. Mission and Goals p3 3. Timelines and Deliverables for first Three Years p8 4. Stakeholders p13 5. SWOT Analysis p13 6. Differentiation Strategy p15 7. Contribution to Campus Mission p15 8. Peer and Aspirant Programs at other Institutions p16 9. Benefit of being an Institute Member to Faculty p16 10. Activities and Accomplishments to Date p16 11. Proposed Resource Needs for the Creation and Operation of INSI p16 12. Next Steps p17 Appendix A: Neuroscience Faculty (UMA and Five College Affiliates) p18 Appendix B: INSI Cluster Proposal Summaries p21 Appendix C: Full Cluster Proposals p23 INSI Steering Committee – 9/4/2015 Page 1 of 52 NS Strategic Plan 2015 Executive Summary In July 2014, the Dean of the College of Natural Sciences, in collaBoration with the VCRE, instituted a Neuroscience Strategic Planning Task Force and charged this task force with developing a strategic vision for neuroscience on the UMA campus, with Both immediate and longer-term oBjectives. MemBers of the task force represented each of the major suBstantive levels of current UMA neuroscience research (cellular/molecular; systems/circuitry; and Behavior/cognition), included assistant, associate, and full professors, and represented four departments in CNS and the School of Public Health and Health Sciences (SPHHS), as well as the Institute of Applied Life Sciences (IALS). The Neuroscience Strategic Planning Task Force has articulated a vision and operational plan for the creation and advancement of a new world-class Integrative Neuroscience Institute at UMA. The Institute will encompass research interests and eXperimental approaches contributed By a Broad range of departments and promote cross-departmental collaborations and close interactions with the Medical School (UMMS) – all leading to unique mechanistic insights into nervous system function in health and disease. -
As the Year 2008 Draws To
FROM THE EDITORS s the year 2008 draws to a close, excitement and an expectation of change hang in the air, and not least in the field of neuroscience. “We have recently had a decade of the brain, and there is a sense that this will be a century of Aneuroscience,” says Pasko Rakic, one of three winners of this year’s Kavli prize for neuroscience, in an interview on page 893. Pasko Rakic, Sten Grillner and Thomas Jessell were recognized for their pioneering work and outstanding contributions to elucidating the development and function of neural circuits. This highly prestigious prize, which will be given biannually in the fields of nanoscience, neuroscience and astrophysics, was awarded ▶ cover: ‘Winter action’ by Kirsten Lee, inspired for the first time this year. The interviews highlight the milestones in the by the Perspective on p957. careers of the awardees, their outlook on neuroscience and their advice for young neuroscientists. This issue also marks the start of a new article series that will cover different aspects of sleep. On page 910, Krueger and colleagues review the accumulated evidence for the hypothesis that sleep is regulated locally through the induction of sleep-like states in individual cortical cLaudia wiedeMann katherine whaLLey columns and that synchronization of these states might lead to whole-animal sleep. Another timely subject, which we cover in this issue’s Science and Society article (page 957), is the rising rate of ADHD diagnosis in children. Ilina Singh discusses the science behind the current diagnostic criteria and Leonie weLberg Monica hoyoS fLight the ethical and social issues that arise from medicating young children.