A Connectomic Atlas of the Human Cerebrum Cordell Baker BS; Joshua Dee Burks; Robert G. Briggs BS; Andrew K.P. Conner MD; Chad A Glenn MD; Goksel Sali; Michael Edward Sughrue MD University of Oklahoma Health Sciences Center Department of Neurosurgery

Introduction Results As knowledge of the brain has increased, The anatomy, functional connectivity, and clinicians have learned that the cerebrum is structural connectivity of all 180 cortical composed of complex networks that interact to parcellations identified in the HCP are compiled execute key functions. While neurosurgeons can into a single supplement. Within each section of typically predict and preserve primary cortical the atlas, we integrate this information, along function through in the visual and motor with what is known about parcellation function to cortices, preservation of higher cognitive summarize the implications of these data on functions that are less well localized has proven network connectivity. more difficult. This suggests these “silent” cortical regions are more anatomically complex and redundant than our previous methods of Conclusions inquiry can explain and that progress in cerebral This multipart supplement aims to build on the surgery will be made with an improved work of the HCP. We present this information in understanding of brain connectomics. Newly the hope that the complexity of cerebral published parcellated brian maps provide one connectomics will be conveyed in a more avenue to study such connectomics in greater manageable format that will allow clinicians and detail, and they provide a superior framework neuroscientists to accurately communicate and and nomenclature for studying cerebral function formulate hypotheses regarding cerebral anatomy and anatomy. and connectivity. We believe access to this information may provide a foundation for improving surgical outcomes by preserving lesser Methods -known networks. We divided the cerebrum into eight macroregions: lateral frontal, motor/premotor, medial frontal, insular, temporal, lateral parietal, Learning Objectives medial parietal and occipital. Using data from By the conclusion of this session, participants the Human Connectome Project (HCP), these should understand the roles of structural and regions were subdivided further into their functional connectivity in the study of the associated parcellations. Connectome cerebral cortex as well as the breadth and Workbench was used to localize parcellations complexity of distinct cortical regions that make anatomically and to demonstrate their functional up the cerebrum. connectivity. DSI studio was used to assess structural connectivity for each parcellation.

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