LGALS3BP Rabbit Pab

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Leader in Biomolecular Solutions for Life Science LGALS3BP Rabbit pAb Catalog No.: A12005 Basic Information Background Catalog No. The galectins are a family of beta-galactoside-binding proteins implicated in A12005 modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency Observed MW virus (HIV). It appears to be implicated in immune response associated with natural killer 70kDa (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The Calculated MW native protein binds specifically to a human macrophage-associated lectin known as 65kDa Mac-2 and also binds galectin 1. Category Primary antibody Applications WB Cross-Reactivity Human, Mouse Recommended Dilutions Immunogen Information WB 1:500 - 1:2000 Gene ID Swiss Prot 3959 Q08380 Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 6-221 of human LGALS3BP (NP_005558.1). Synonyms LGALS3BP;90K;BTBD17B;CyCAP;M2BP;MAC-2-BP;TANGO10B;gp90 Contact Product Information www.abclonal.com Source Isotype Purification Rabbit IgG Affinity purification Storage Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. Validation Data Western blot analysis of extracts of various cell lines, using LGALS3BP antibody (A12005) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. Antibody | Protein | ELISA Kits | Enzyme | NGS | Service For research use only. Not for therapeutic or diagnostic purposes. Please visit http://abclonal.com for a complete listing of recommended products..

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Datasheet A02938-1 Anti-LGALS3BP Antibody
Product datasheet Anti-LGALS3BP Antibody Catalog Number: A02938-1 BOSTER BIOLOGICAL TECHNOLOGY Special NO.1, International Enterprise Center, 2nd Guanshan Road, Wuhan, China Web: www.boster.com.cn Phone: +86 27 67845390 Fax: +86 27 67845390 Email: [email protected] Basic Information Product Name Anti-LGALS3BP Antibody Gene Name LGALS3BP Source Rabbit IgG Species Reactivity human,mouse Tested Application WB,IHC-P Contents 500ug/ml antibody with PBS ，0.02% NaN3 , 1mg BSA and 50% glycerol. Immunogen A synthetic peptide corresponding to a sequence of human LGALS3BP (HEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPR). Purification Immunogen affinity purified. Observed MW 65KD Dilution Ratios Western blot: 1:500-2000 Immunohistochemistry in paraffin section: 1:50-400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. Storage 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing Background Information Galectin-3-binding protein is a protein that in humans is encoded by the LGALS3BP gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25.
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Pancreatic Cancer Invasion of the Lymphatic Vasculature and Contributions of the Tumor Microenvironment: Roles for E- Selectin and CXCR4
University of Nebraska Medical Center DigitalCommons@UNMC Theses & Dissertations Graduate Studies Fall 12-16-2016 Pancreatic Cancer Invasion of the Lymphatic Vasculature and Contributions of the Tumor Microenvironment: Roles for E- selectin and CXCR4 Maria M. Steele University of Nebraska Medical Center Follow this and additional works at: https://digitalcommons.unmc.edu/etd Recommended Citation Steele, Maria M., "Pancreatic Cancer Invasion of the Lymphatic Vasculature and Contributions of the Tumor Microenvironment: Roles for E-selectin and CXCR4" (2016). Theses & Dissertations. 166. https://digitalcommons.unmc.edu/etd/166 This Dissertation is brought to you for free and open access by the Graduate Studies at DigitalCommons@UNMC. It has been accepted for inclusion in Theses & Dissertations by an authorized administrator of DigitalCommons@UNMC. For more information, please contact [email protected]. i PANCREATIC CANCER INVASION OF THE LYMPHATIC VASCULATURE AND CONTRIBUTIONS OF THE TUMOR MICROENVIRONMENT: ROLES FOR E-SELECTIN AND CXCR4 By Maria M. Steele A DISSERTATION Presented to the Faculty of the University of Nebraska Graduate College in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Cancer Research Graduate Program Under the Supervision of Professor Michael A. Hollingsworth University of Nebraska Medical Center Omaha, NE November, 2016 Supervisory Committee Michael A. Hollingsworth, Ph.D. Kaustubh Datta, Ph.D. Angie Rizzino, Ph.D. Joyce C. Solheim, Ph.D. ii PANCREATIC CANCER INVASION OF THE LYMPHATIC VASCULATURE AND CONTRIBUTIONS OF THE TUMOR MICROENVIRONMENT: ROLES FOR E-SELECTIN AND CXCR4 Maria M. Steele University of Nebraska, 2016 Advisor: Michael A. Hollingsworth ABSTRACT As the fourth leading cause of cancer-related deaths, pancreatic cancer is one of the most lethal forms of cancers in the United States.
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King's Research Portal
King’s Research Portal DOI: 10.3892/ijo.2016.3521 Document Version Peer reviewed version Link to publication record in King's Research Portal Citation for published version (APA): Woodman, N., Pinder, S. E., Tajadura, V., Le Bourhis, X., Gillett, C., Delannoy, P., Burchell, J. M., & Julien, S. (2016). Two E-selectin ligands, BST-2 and LGALS3BP, predict metastasis and poor survival of ER-negative breast cancer. International Journal of Oncology, 49(1), 265-275. https://doi.org/10.3892/ijo.2016.3521 Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version. If citing, it is advised that you check and use the publisher's definitive version for pagination, volume/issue, and date of publication details. And where the final published version is provided on the Research Portal, if citing you are again advised to check the publisher's website for any subsequent corrections. General rights Copyright and moral rights for the publications made accessible in the Research Portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognize and abide by the legal requirements associated with these rights. •Users may download and print one copy of any publication from the Research Portal for the purpose of private study or research. •You may not further distribute the material or use it for any profit-making activity or commercial gain •You may freely distribute the URL identifying the publication in the Research Portal Take down policy If you believe that this document breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim.
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Human Lectins, Their Carbohydrate Affinities and Where to Find Them
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Supplementary Material Contents
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LGALS3BP Mouse Monoclonal Antibody [Clone ID: OTI1C2] Product Data
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LGALS3BP Antibody
LGALS3BP Antibody CATALOG NUMBER: 26-926 Antibody used in WB on Human Brain at 0.2-1 ug/ml. Specifications SPECIES REACTIVITY: Human, Mouse TESTED APPLICATIONS: ELISA, WB APPLICATIONS: LGALS3BP antibody can be used for detection of LGALS3BP by ELISA at 1:312500. LGALS3BP antibody can be used for detection of LGALS3BP by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. USER NOTE: Optimal dilutions for each application to be determined by the researcher. POSITIVE CONTROL: 1) Cat. No. XBL-10123 - Fetal Brain Tissue Lysate PREDICTED MOLECULAR 63 kDa WEIGHT: IMMUNOGEN: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LGALS3BP. HOST SPECIES: Rabbit Properties PURIFICATION: Antibody is purified by peptide affinity chromatography method. PHYSICAL STATE: Lyophilized BUFFER: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 uL of distilled water. Final antibody concentration is 1 mg/mL. CONCENTRATION: 1 mg/ml STORAGE CONDITIONS: For short periods of storage (days) store at 4˚C. For longer periods of storage, store LGALS3BP antibody at - 20˚C. As with any antibody avoid repeat freeze-thaw cycles. CLONALITY: Polyclonal CONJUGATE: Unconjugated Additional Info ALTERNATE NAMES: LGALS3BP, 90K, MAC-2-BP, BTBD17B, TANGO10B ACCESSION NO.: NP_005558 PROTEIN GI NO.: 5031863 OFFICIAL SYMBOL: LGALS3BP GENE ID: 3959 Background BACKGROUND: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV).
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The N-Terminal Domain of the Spike Protein As Another Emerging Target for Hampering the SARS-Cov-2 Attachment to Host Cells
International Journal of Molecular Sciences Perspective More Is Always Better Than One: The N-Terminal Domain of the Spike Protein as Another Emerging Target for Hampering the SARS-CoV-2 Attachment to Host Cells Sonia Di Gaetano 1,2,† , Domenica Capasso 2,3,† , Pietro Delre 4,5, Luciano Pirone 1 , Michele Saviano 2,4, Emilia Pedone 1,2,* and Giuseppe Felice Mangiatordi 4 1 Institute of Biostructures and Bioimaging, CNR, 80134 Naples, Italy; [email protected] (S.D.G.); [email protected] (L.P.) 2 CIRPEB, University of Naples “Federico II”, 80134 Naples, Italy; [email protected] (D.C.); [email protected] (M.S.) 3 CESTEV, University of Naples “Federico II”, 80145 Naples, Italy 4 Institute of Crystallography, CNR, 70126 Bari, Italy; [email protected] (P.D.); [email protected] (G.F.M.) 5 Chemistry Department, University of Bari, 70121 Bari, Italy * Correspondence: [email protected]; Tel.: +39-081-253-4521 † The authors contribute equally to this work. Abstract: Although the approved vaccines are proving to be of utmost importance in containing the Coronavirus disease 2019 (COVID-19) threat, they will hardly be resolutive as new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, a single-stranded RNA virus) variants might be Citation: Di Gaetano, S.; Capasso, D.; insensitive to the immune response they induce. In this scenario, developing an effective therapy is Delre, P.; Pirone, L.; Saviano, M.; still a dire need. Different targets for therapeutic antibodies and diagnostics have been identiﬁed, Pedone, E.; Mangiatordi, G.F. More Is among which the SARS-CoV-2 spike (S) glycoprotein, particularly its receptor-binding domain, has Always Better Than One: The been deﬁned as crucial.
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LGALS3BP Mouse Monoclonal Antibody [Clone ID: OTI1C2] Product Data
OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for TA503456 LGALS3BP Mouse Monoclonal Antibody [Clone ID: OTI1C2] Product data: Product Type: Primary Antibodies Clone Name: OTI1C2 Applications: FC, IF, WB Recommended Dilution: WB 1:2000, IF 1:100, FLOW 1:100 Reactivity: Human Host: Mouse Isotype: IgG1 Clonality: Monoclonal Immunogen: Human recombinant protein fragment corresponding to amino acids 19-300 of human LGALS3BP(NP_005558) produced in E.coli. Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. Concentration: 1 mg/ml Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) Conjugation: Unconjugated Storage: Store at -20°C as received. Stability: Stable for 12 months from date of receipt. Predicted Protein Size: 65.2 kDa Gene Name: galectin 3 binding protein Database Link: NP_005558 Entrez Gene 3959 Human Q08380 This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 3 LGALS3BP Mouse Monoclonal Antibody [Clone ID: OTI1C2] – TA503456 Background: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell- cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine- activated killer (LAK) cell cytotoxicity.
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GSE50161, (C) GSE66354, (D) GSE74195 and (E) GSE86574
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