LGALS3BP Antibody

CATALOG NUMBER: 26-926

Antibody used in WB on Human Brain at 0.2-1 ug/ml.

Specifications SPECIES REACTIVITY: Human, Mouse TESTED APPLICATIONS: ELISA, WB APPLICATIONS: LGALS3BP antibody can be used for detection of LGALS3BP by ELISA at 1:312500. LGALS3BP antibody can be used for detection of LGALS3BP by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. USER NOTE: Optimal dilutions for each application to be determined by the researcher. POSITIVE CONTROL: 1) Cat. No. XBL-10123 - Fetal Brain Tissue Lysate PREDICTED MOLECULAR 63 kDa WEIGHT: IMMUNOGEN: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LGALS3BP. HOST SPECIES: Rabbit

Properties PURIFICATION: Antibody is purified by peptide affinity chromatography method. PHYSICAL STATE: Lyophilized BUFFER: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 uL of distilled water. Final antibody concentration is 1 mg/mL. CONCENTRATION: 1 mg/ml STORAGE CONDITIONS: For short periods of storage (days) store at 4˚C. For longer periods of storage, store LGALS3BP antibody at - 20˚C. As with any antibody avoid repeat freeze-thaw cycles. CLONALITY: Polyclonal CONJUGATE: Unconjugated

Additional Info ALTERNATE NAMES: LGALS3BP, 90K, MAC-2-BP, BTBD17B, TANGO10B ACCESSION NO.: NP_005558 GI NO.: 5031863 OFFICIAL SYMBOL: LGALS3BP ID: 3959

Background BACKGROUND: The are a family of beta-galactoside-binding implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds 1.The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine- activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. REFERENCES: 1) Lee, Y.J., Clin. Exp. Rheumatol. 25 (4 SUPPL 45), S41-S45 (2007).

FOR RESEARCH USE ONLY

December 12, 2016