Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000293525Cyc: Bacillus cereus BAG6O-1 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari a purine 2-dehydro- 2-dehydro- 1-(β-D ammonium putrescine putrescine a pyrimidine a pyrimidine a pyrimidine nucleoside 3-deoxy-D- 3-deoxy-D- ribofuranosyl) a tricarboxylate a macrolide (S)-malate bacitracin bacitracin D-fructose a siderophore spermidine spermidine nucleoside nucleoside nucleoside uracil gluconate gluconate nicotinamide

RS20590 RS30665 RS22165 RS06625 RS01640 RS23870 RS02440 RS02445 RS23735 RS05020 RS09575 RS09175 RS08280 RS12590 RS02275 RS10905 RS03475 RS25635

putrescine putrescine ammonium a pyrimidine a pyrimidine a pyrimidine D-fructose uracil 2-dehydro- 2-dehydro- 1-(β-D a tricarboxylate a macrolide (S)-malate bacitracin bacitracin a siderophore spermidine spermidine nucleoside nucleoside nucleoside 1-phosphate a purine 3-deoxy-D- 3-deoxy-D- ribofuranosyl) nucleoside gluconate gluconate nicotinamide

TCA cycle Aldehyde superpathway of pyrimidine Nucleoside and Nucleotide Degradation Degradation undecaprenyl- an [amino group 1-cis-vaccenoyl- 1-myristoyl- a [protein] deoxyribonucleosides degradation a 2,3,4-saturated a 2,3,4-saturated 2- a cis- sn-glycerol sn-glycerol 5'-deoxy-5'- O-succinyl-L- sn-glycerol L-histidine biosynthesis L-lysine biosynthesis II Amino Acid Biosynthesis diphospho-N- a stearoyl-[acp] methyl red methanethiol carrier protein]- sn-glycerol- sn-glycerol (L-serine/L- a protein L-arginine biosynthesis I (via L-ornithine) L-methionine salvage cycle I (bacteria and plants) superpathway of glyoxylate bypass and TCA methylglyoxal fatty acyl-[acp] lysophosphatidate vaccenoyl-[acp] 3-phosphate 3-phosphate fluoroadenosine homoserine 3-phosphate superpathway of branched chain amino acid biosynthesis Aminoacyl-tRNA Charging 2'-deoxycytidine purine-nucleoside γ 3-phosphate 3-phosphate threonine) degradation I acetylmuramoyl- UDP-N-acetyl- 1-acyl-sn-glycerol- glycerol-3- glycerol-3- FMN-dependent cystathionine C-terminal- - 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- glycerol-3- Clp protease PRPP L-alanyl-γ-D- α-D-glucosamine NADH- phosphorylase: (L-ornithyl) phosphate ClpP: asp acetyl-CoA 3-phosphate phosphate 1-O- phosphate 1-O- gamma- acetylornithine 3-phosphate 3-phosphate protein phosphate 1-O- glu pyruvate met tRNA charging cytidine methylglyoxal glutamyl-L-lysyl- undecaprenyldiphospho- azoreductase: deoD -L-glutamate IEK_RS14485 aspartate thr gln acyltransferase: acyltransferase acyltransferase synthase: transaminase: acyltransferase: acyltransferase: phosphatase acyltransferase ATP 2-oxoglutaramate glutaminyl-tRNA deaminase: D-alanyl-D-alanine muramoylpentapeptide beta-N- IEK_RS21970 purine-nucleoside kinase: arginine-- lactoylglutathione IEK_RS25595 PlsY: PlsY: IEK_RS05760 IEK_RS07050 IEK_RS25595 IEK_RS25595 2C domain- PlsY: ATP- phosphoribosyltransferase: bifunctional acetolactate biosynthesis via transamidation IEK_RS17965 acetylglucosaminyltransferase: threonine oxaloacetate citrate synthase: thymidine lyase: IEK_RS22710 1-acyl-sn-glycerol- IEK_RS09850 IEK_RS09850 FMN-dependent phosphorylase: containing IEK_RS09850 dependent IEK_RS19975 IEK_RS18295 synthase, 2-oxoglutaramate tRNA ligase: ditrans,octacisIEK_RS06345- cystathionine acetylornithine 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- glutamate N- dehydratase: cytidine (R)-S- NADH- IEK_RS07260 protein: aspartate large subunit, IEK_RS16500 IEK_RS15915 undecaprenyldiphospho- 3-phosphate glycerol-3- glycerol-3- gamma- an [amino groupaminotransferase: 3-phosphate 3-phosphate glycerol-3- Clp protease [+ 2 isozymes] acetyltransferase/ amidase: IEK_RS07525 glu deaminase: pyrimidine- lactoylglutathione [+ 2 isozymes] 5-fluoro-5- IEK_RS18135 S-adenosylmethionine malate:quinone citrate synthase: N-acetyl-(N-acetyl-β-D- acyltransferase: phosphate 1-O- phosphate 1-O- azoreductase synthase: IEK_RS12410 IEK_RS13625 phosphate 1-O- proteolytic kinase: amino-acid biosynthetic arginine-- acetyl-CoA nucleoside deoxy-D-ribose adenine carrier protein]- acyltransferase: acyltransferase: a [protein] Ser/Thr β threonine synthase: IEK_RS03865 arg oxidoreductase: IEK_RS06105 UDP IEK_RS16360 acyltransferase acyltransferase 4: IEK_RS00805 IEK_RS06325 acyltransferase subunit: clpP 1-(5-phospho- -D-ribosyl)-ATP IEK_RS08735 acetyltransferase type: ilvB 2-oxoglutarate tRNA ligase: IEK_RS04735 phosphorylase: glucosaminyl)muramoyl- a 2,3,4-saturated N,N-dimethyl-1,4- 1-phosphate C-terminal-γ- 1-cis-vaccenoyl-IEK_RS16360 1-myristoyl-2-IEK_RS16360 L-aspartyl- ammonia-lyase: IEK_RS12680 γ PlsY: PlsY: anthranilate PlsY: ArgJ: IEK_RS07040 [+ 2 isozymes] IEK_RS01030 an L-arginyl- deoA L-alanyl- -D-glutamyl-L- 1,2-diacyl-sn phenylenediamine succinate met (L-glutamate 5- 2-palmitoleoyl- palmitoleoyl- a peptide 4-phosphate IEK_RS24660 malate dehydrogenase: mdh 2'-deoxyuridine acyl-carrier protein phosphoribosyl-ATP L-isoleucine Arg lysyl-D-alanyl-D-alanine -glycerol 3- IEK_RS15340 IEK_RS153401-stearoyl- semialdehyde-2- sn-glycerol- sn-glycerol 1-oleoyl-snIEK_RS15340 superpathway of L-homoserine and L-methionine biosynthesis 4-(methylsulfanyl)-2-oxobutanoate SAM [tRNA ] pyrimidine- (R)-lactate 1-cis-vaccenoyl- diphosphatase: hisE N-acetyl-L- (S)-2-acetolactate biosynthesis IV Arg aspartate- (2Z)-2-aminobut- adenosylmethionine a tRNA an L-glutamyl- (S)-malate citrate nucleoside phosphate acyl-carrier protein sn-glycerol- acyl-carrier protein sn-glycerol yl)-L-glutamate 3-phosphate 3-phosphate -glycerol 3- glutamate Gln citrate RS23960 citrate 2-enoate decarboxylase: [tRNA ] malate synthase 3-phosphate 3-phosphate phosphate β semialdehyde ketol-acid phosphorylase: 1-(5-phospho- -D-ribosyl)-AMP IEK_RS01830 propanoate dehydrogenase: acetylglutamate reductoisomerase: asp Asp-tRNA(Asn) A: IEK_RS21395 deoA IEK_RS15485 kinase: argB acyl-CoA gln superpathway of purine deoxyribonucleosides degradation phosphoribosyl-AMP IEK_RS18145 adenosylmethionine /Glu-tRNA(Gln) class II fumarate aconitate hydratase 1-stearoyl- 1-cis-vaccenoyl- 5'-chloro-5'- 1-cis-vaccenoyl- 1-palmitoyl- (S)-4-amino-5- D-ribose 5- aspartate kinase: synthetase: cysteine- thymine pyruvate sn-glycerol 1-(18-hydroxyoleoyl)- O-phospho- cyclohydrolase: aspartate- acetylglutamate decarboxylase: amidotransferase hydratase: fumC a palmitoleoyl-[acp] a malonyl-[acp] an oleoyl-[acp] sn-glycerol a palmitoleoyl-[acp] sn-glycerol- a myristoyl-[acp] a purine cys sn-glycerol- sn-glycerol biotin RS09735 biotin ketol-acid IEK_RS09740 CTP synthase: AcnA: acnA pyrimidine- deoxyadenosine sn-glycrol 3-phosphate thr oxopentanoate phosphate IEK_RS19945 semialdehyde kinase: 2-iminobutanoate IEK_RS18295 IEK_RS04795 -tRNA subunit GatA: fumarate hydratase: 3-phosphate 3-phosphate ribonucleoside purine-nucleoside L-homoserine glutamate-1- ribose 5- reductoisomerase: cys IEK_RS15495 nucleoside 3-oxoacyl-[acyl- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol-3-phosphate glycerol-3- 1-acyl-sn-glycerol- cystathionine 3-phosphate 3-phosphate1-acyl-sn-glycerol- 1-(5-phospho-β-D-ribosyl)- IEK_RS13450 aspartate kinase: [+ 4 isozymes] ligase: 2'-deoxyguanosine purine-nucleoside 1-acyl-sn-glycerol- threonine dehydrogenase: IEK_RS20005 1,2-dihydroxy-5- IEK_RS24995 IEK_RS24410 phosphorylase: 3-phosphate phosphorylase: semialdehyde phosphate IEK_RS08735 dAdoMet propanoyl-CoA cysS [+ 13 isozymes] fumarate cis-aconitate carrier-protein] 3-phosphate phosphate 1-O- 3-phosphate gamma- 3-phosphate 3-phosphate dehydratase: 5-[(5-phosphoribosylamino) asd N-acetylglutamyl- (2R)-2,3- (methylsulfanyl)pent-1-en-3-one an L-cysteinyl- a 5-phosphooxy- deoA 2'-deoxyadenosine phosphorylase: deoD 2,1- isomerase a reduced Cys aconitate hydratase reductase: acyltransferase: acyltransferase: acyltransferase acyltransferase: synthase: acyltransferase: acyltransferase: IEK_RS18135 methylideneamino]imidazole- [tRNA ] L-glutamyl- glyoxylate deoD aminomutase: B: rpiB H O c-type phosphate dihydroxy-3- 2-oxoacid ammonium IEK_RS08480 IEK_RS25595 IEK_RS25595 PlsY: purine-nucleoside IEK_RS25595 IEK_RS05760 2 L-aspartate 4- putrescine Cys Gln succinate dehydrogenase: AcnA: acnA pyrimidine- IEK_RS25595 IEK_RS25595 cytochrome 4-carboxamide methylbutanoate L-aspartyl-4-phosphate 2-hydroxy-3-keto-5- a tRNA [tRNA ] purine-nucleoside threonine IEK_RS24190 cytochrome semialdehyde N-acetyl- 2-oxobutanoate ferredoxin nucleoside purine-nucleoside beta-ketoacyl-[acyl- IEK_RS09850 phosphorylase: ribose 5- an oxidized 1-(5-phosphoribosyl)-5- methylthiopentenyl-1- spermidine synthase: IEK_RS05115 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- phosphorylase: 1-acyl-sn-glycerol- cystathionine 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- ammonia-lyase: c oxidase 2,3-dihydroxy- oxidoreductase phosphorylase: phosphorylase: IEK_RS07260 glutamate-1- phosphate O c-type [(5- phosphoribosylamino) 4-hydroxy- gamma- phosphate phosphatase: Asp-tRNA(Asn) IEK_RS05120 carrier-protein] 3-phosphate 3-phosphate glycerol-3- 3-phosphate gamma- 3-phosphate 3-phosphate IEK_RS24660 2 isovalerate acetolactate aspartate-semialdehyde IEK_RS01835 subunit beta: IEK_RS07260 IEK_RS07260 5-chloro-5- cytochrome glutamyl- IEK_RS07510 spermidine /Glu-tRNA(Gln) isocitrate lyase: deoA synthase II: fabF acyltransferase: acyltransferase: phosphate 1-O- α-D-ribose- acyltransferase: synthase: acyltransferase: acyltransferase: semialdehyde isomerase AI-2 RS12670 AI-2 methylideneamino]imidazole-4- tetrahydrodipicolinate dehydrogenase: IEK_RS08875 adenine deoxyribose 2-oxobutanoate phosphate dehydratase: synthase, IEK_RS21390 purine-nucleoside an (11Z)-3-oxooctadec- IEK_RS16360 IEK_RS16360 acyltransferase 1-phosphate a purine base IEK_RS16360 IEK_RS06325 2,1- A: rpiA carboxamide isomerase: hisA synthase: IEK_RS08740 IEK_RS15485 amidotransferase succinate D-threo-isocitrate acyl-carrier protein 1-stearoyl-2- 1-cis-vaccenoyl- 1-phosphate 1-[18-hydroxyoeoyl]-2- 1,2-dicis- IEK_RS16360 1-palmitoyl-2-IEK_RS16360 D-ribulose reductase: ilvD large subunit, purine-nucleoside phosphorylase: 11-enoyl-[acp] PlsY: aminomutase: 4-hydroxy- 2-hydroxy-5-(methylsulfanyl)- 2-oxobutanoate gln subunit GatA: NADP-dependent 2'-deoxyinosine acyl-carrier protein oleoyl-sn-glycerol 2-palmitoleoyl- [18-hydroxy-lioleoyl]-sn L-cystathionine vaccenoyl- palmitoleoyl- 5-phosphate phosphoribulosylformimino- IEK_RS07035 3-methyl-2- biosynthetic aspartate-semialdehyde S-methyl-5'-thioadenosine deoD acyl-carrier protein hemL 3-oxopent-1-enyl 1-phosphate IEK_RS24995 isocitrate dehydrogenase: succinate phosphorylase: 3-phosphate sn-glycerol- IEK_RS15340 -glycerol 3-phosphate phosphatidate sn-glycerol AICAR-phosphate tetrahydrodipicolinate N-acetyl-L- oxobutanoate type: ilvB dehydrogenase: asd 5'-methylthioadenosine/ an L-glutaminyl- succinyl-CoA ligase 1-myristoyl- AI-2 RS12675 AI-2 acetolactate IEK_RS04740 IEK_RS07260 3-phosphate 3-phosphate 5-aminolevulinate synthase: dapA S-adenosylhomocysteine [tRNA Gln ] acyl-carrier protein sn-glycerol (2S,4S)-4- glutamate 5- [+ 2 isozymes] synthase, subunit beta: IEK_RS08555 purine-nucleoside L-aspartate 4-semialdehyde 2,3-diketo-5- nucleosidase: mtnN a tRNA Gln an L-glutaminyl- purine-nucleoside 3-phosphate imidazole glycerol semialdehyde 2-isopropylmalate branched-chain- (S)-2-aceto-2- large subunit, uracil 2-deoxy-α- hydroxy-2,3,4,5- methylthiopentyl-1- [tRNA Gln ] phosphorylase: phosphorylase: phosphate synthase: acetylornithine synthase: amino-acid [+ 4 isozymes] D-ribose 1- Na + PanF Na + tetrahydrodipicolinate hydroxybutanoate homoserine phosphate enolase: mtnW biosynthetic deoD IEK_RS07260 IEK_RS19950 hisH transaminase: IEK_RS20000 phosphate an inactive 1-stearoyl- a ribonucleoside 1939 a 1-alkyl-sn a 1-acyl-sn 4-hydroxy- transaminase: ketol-acid dehydrogenase: type: ilvB succinyl-CoA 2-oxoglutarate an acyl-[acyl- sn-glycerol α-D- a uracil IEK_RS07050 purine-nucleoside ribonucleoside a reduced sn-glycerol a palmitoyl-[acp] a purine 2'- 2',3'-cyclic -glycerol 3- -glycerol 3- a folate GGPP IPP a malonyl-[acp] imidazole glycerol tetrahydrodipicolinate IEK_RS18160 reductoisomerase: IEK_RS14690 [+ 2 isozymes] phosphopentomutase: SAM inosine carrier protein] 3-phosphate glucopyranose ATP in 23S rRNA (2S)-2- phosphorylase: triphosphate flavodoxin 3-phosphate deoxyribonucleoside phosphate 23S rRNA phosphate phosphate dihydrofolate phosphate synthase: reductase: IEK_RS19355 acetylornithine branched-chain- IEK_RS18145 [+ 2 isozymes] deoB 1-acyl-sn-glycerol- glycerol-3- 1-phosphate bifunctional 2',3'- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- heptaprenyl beta- 2+ 2+ isopropylmalate 5-(methylsulfanyl)-2,3-dioxopentyl 1-phosphate MTR (S)-2-aceto-2- glu deoD reductase anaerobic inosine-uridine purine-nucleoside glucose-1-phosphate (uracil(1939)-C(5)) reductase: Cd CadA Cd IEK_RS20045 aminotransferase: amino-acid ketol-acid 2-deoxy-D-ribose 3-phosphate phosphate 1-O- cyclic-nucleotide 2'- 3-phosphate 3-phosphate diphosphate ketoacyl- (S)-2,3,4,5- S-methyl-5-thioribose hydroxybutanoate ribonucleoside- preferring nucleoside phosphorylase: adenylyltransferase: -methyltransferase IEK_RS16375 IEK_RS12410 3-isopropylmalate transaminase: reductoisomerase: L-homoserine an L-glutamyl- 2-oxoglutarate 5-phosphate α acyltransferase: acyltransferase phosphodiesterase/ acyltransferase: acyltransferase: synthase [acyl- tetrahydrodipicolinate kinase: IEK_RS24860 2-aceto-2-hydroxy- Fermentation 2-deoxy- -D- triphosphate hydrolase: IEK_RS02215 deoD IEK_RS03355 RlmD: IEK_RS24395 dehydratase: methylthioribulose Glu dehydrogenase E1 IEK_RS16360 PlsY: 3'-nucleotidase: IEK_RS16360 dihydrofolate component carrier- AICAR D-erythro-imidazole- 2,3,4,5- N-acetyl-L- IEK_RS20020 IEK_RS20005 S-methyl-5-thioribose butanoate [tRNA ] ribose 1-phosphate reductase IEK_RS25595 leuD leuC 1-phosphate a tRNA glu inosine-uridine IEK_RS09850 purine-nucleoside glucose-1-phosphate 23S rRNA reductase: II: hepT a purine RS19175 a purine glycerol-phosphate ornithine homoserine O- component: IEK_RS20735 deoxyribose- inosine 5'-phosphate 1-acyl-sn-glycerol- IEK_RS07080 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- protein] tetrahydropyridine- (R)-2,3-dihydroxy- dehydratase: mtnB kinase: IEK_RS07530 isomeroreductase: phosphopentomutase: activating preferring nucleoside phosphorylase: adenylyltransferase: (uracil(1939)-C(5)) IEK_RS23510 imidazoleglycerol- hydrogencarbonate succinyltransferase: pyruvate phosphate degradation an active 3-phosphate glycerol-3- [+ 2 isozymes] 3-phosphate 3-phosphate heptaprenyl synthase 2,6-dicarboxylate N- acetylornithine 2-isopropylmaleate val 3-methylpentanoate IEK_RS20005 deoB protein: nrdG hydrolase: IEK_RS13085 2-deoxy-α- IEK_RS07260 IEK_RS03360 a ribonucleoside -methyltransferase IEK_RS00830 fermentation aldolase: a flavodoxin ribonucleoside acyltransferase: phosphate 1-O- acyltransferase: acyltransferase: a 7,8-dihydrofolate diphosphate a 3- II: fabF phosphate acetyltransferase: carbamoyl- deacetylase: 2,3-dihydroxy-3- (R)-2,3-dihydroxy- met 5'-deoxyadenosine hypoxanthine D-ribofuranose D-ribose 1- a purine base ADP-α-D-glucose 3'-phosphate RlmD: IEK_RS24930 3-isopropylmalate to (R)-acetoin II deoC 2-deoxy-D-ribose semiquinone triphosphate IEK_RS25595 acyltransferase a 5- IEK_RS25595 IEK_RS16360 synthase: a purine RS00880 a purine dehydratase dapD IEK_RS16090 methylvalerate 3-methylpentanoate a 1-stearoyl 2- phosphate a 2-acyl-1-alkyl- a 1-acyl-2- oxodocosanoyl- phosphate cys O-succinyl-L-homoserine isoleucine-- 5-phosphate IMP 1939 IEK_RS19455 HisB: hisB dehydratase: hydro-lyase: ilvD 5-(methylsulfanyl)-ribulose 1-phosphate 5-MTR-1-P Respiration pyruvate reductase acyl-carrier protein acyl-sn-glycerol PlsY: methyluracil sn-glycerol palmitoyl-sn all-trans- [acp] L-2-acetamido-6- synthase: acetylornithine 2,3-dihydroxy-3- tRNA ligase: D-glyceraldehyde IMP leuD leuC acetolactate 3-phosphate IEK_RS153401-palmitoyl- in 23S rRNA 3-phosphate -glycerol 3- heptaprenyl oxoheptanedioate IEK_RS08295 deacetylase: (S)-3-methyl-2- cystathionine gamma- methylvalerate IEK_RS16485 acetaldehyde 3-phosphate deoxyribose- dehydrogenase: imidazole acetol-phosphate (2R,3S)-3- synthase, acyl-carrier protein sn-glycerol phosphate diphosphate IEK_RS08300 IEK_RS24365 oxopentanoate hydro-lyase: ilvD 2-oxoglutarate decarboxylation to succinyl-CoA phosphate K(+)- isopropylmalate synthase: IEK_RS05760 isoleucine-- large subunit, acetaldehyde IEK_RS00345 ile 3-phosphate K + transporting K + histidinol-phosphate branched-chain- cystathionine gamma- (S)-3-methyl-2- aldolase: deoC XMP carbamoyl L-ornithine 3-isopropylmalate tRNA ligase: a [2-oxoglutarate biosynthetic dehydrogenase: transaminase: amino-acid S-methyl-5-thioribose-1- oxopentanoate ATPase phosphate dehydrogenase: synthase: IEK_RS06325 L-cysteine biosynthesis IEK_RS08255 an L-isoleucyl- dehydrogenase type: ilvB IEK_RS05765 IEK_RS19425 N-acetyl-L,L-2,6- transaminase: phosphate isomerase: mtnA bifunctional 1-myristoyl- 1-palmitoyl- 3-oxo-2-(cis- 1-myristoyl- an [amino group (3R,5S)-3- VI (from L-methionine) branched-chain- [tRNA Ile ] 6 acetaldehyde leuB E2 protein] N 2-oxoglutarate [+ 2 isozymes] D-glyceraldehyde 3-phosphate quinoxaline-2- sn-glycerol 3-phosphate MEP diaminopimelate IEK_RS18160 L-cystathionine S-methyl-5-thioribose-1- amino-acid Ile acetyl-CoA metallophosphatase/ a glutaryl-[acp] methyl ester a malonyl-[acp] aryl-carrier protein a myristoyl-[acp] sn-glycerol a palmitoleoyl-[acp] sn-glycerol 2'-pentenyl)- 2-oxoglutarate D-ala sn-glycerol carrier protein]- hydroxy-1- + + histidinol-phosphate ornithine (2S)-2-isopropyl- a tRNA -lipoyl-L-lysine (S)-2-acetolactate carboxyl adenylate GTP H O formate ATP K RS23010 K N-acetyldiaminopimelate phosphate isomerase: mtnA transaminase: dehydrogenase acetaldehyde 5'-nucleotidase: 3-oxoacyl-[acyl-carrier- 3-phosphate 3-phosphate glycerol-3-phosphate cyclopentane-1- 2 D-amino-acid 3-phosphate C-terminal-γ- pyrroline-5- transaminase: carbamoyltransferase: branched-chain- met 2-oxoglutarate acyl carrier 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- ribosome 1-acyl-sn-glycerol- 1-deoxy-D-xylulose- 3-oxosuccinate E1 component: IEK_RS11980 1-O-acyltransferase (3-oxooctanoyl) anaerobic (L-glutamate 5- carboxylatepyrroline-5- IEK_RS12765 deacetylase: argF amino-acid S-adenosylmethionine IEK_RS18160 acetolactate dehydrogenase: protein] reductase: protein: 3-phosphate 3-phosphate acetyl-CoA C- transaminase: 3-phosphate 5-phosphate L-cystathione β- dehydrogenase IEK_RS20735 -CoA small subunit- ribonucleoside- N-acetyl- IEK_RS07815 transaminase: synthase: branched-chain- decarboxylase: IEK_RS05765 [+ 2 isozymes] IEK_RS08480 IEK_RS17380 acyltransferase: acyltransferase: PlsY: IEK_RS09850 dat acyltransferase: reductoisomerase: semialdehyde-2- carboxylate E1 component: acyltransferase: dependent triphosphate Co 2+ RS11230 2+ L-histidinol phosphate IEK_RS20020 lyase: IEK_RS05760 budA guanosine nucleotides IEK_RS25595 IEK_RS25595 glycerol-3-phosphate IEK_RS08630 yl)-L-glutamategamma- reductase: Co L,L- IEK_RS03865 amino-acid leucine-- IEK_RS20735 beta-ketoacyl-[acyl-carrier- acyl carrier IEK_RS01120 GTPase A: rsgA D-amino-acid IEK_RS25595 reductase: nrdD L-arginine biosynthesis II (acetyl cycle) leu acetyl-CoA degradation III xanthosine 3-oxo-2-(cis- glutamyl- IEK_RS25640 L-citrulline 4-methyl-2- SAM transaminase: protein] synthase II: fabF protein: 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-O-acyltransferase [+ 2 isozymes] transaminase: 1-deoxy-D-xylulose- histidinol- diaminopimelate tRNA ligase: [+ 3 isozymes]a [2-oxoglutarate a [2-oxoglutarate (R)-acetoin 2'-pentenyl)- [+ 7 isozymes] 1-acyl-sn-glycerol- dATP phosphate oxopentanoate ile 2-aminoprop-2-enoate IEK_RS20020 acyl-carrier protein a 3-oxopimeloyl-[acp] methyl ester IEK_RS08485 3-phosphate 3-phosphate PlsY: IEK_RS15340 acetyl-CoA IEK_RS01730 5-phosphate [+ 2 isozymes] L-homocysteine IEK_RS03985 an L-leucyl- + 3-phosphate an [amino groupreductase: phosphatase: diaminopimelate N-acetylglutamyl- dehydrogenase dehydrogenase a quinoxaline-2- 1-(18-hydroxyoleoyl)- cyclopentane-1- phosphate GDP H Hyp 2+ 2+ argininosuccinate Leu purine-nucleoside acyltransferase: acyltransferase: reductoisomerase: Ca Cax Ca IEK_RS19935 epimerase: branched-chain- phosphate [tRNA ] E2 protein] N 6 E2 protein] N 6 -S- GMP AMP carboxyl-[aryl- sn-glycrol 3-phosphate hexanoyl-CoA pyruvate D-glt acyltransferase: carrier protein]-IEK_RS07035 synthase: ile Leu IEK_RS16360 IEK_RS16360 IEK_RS11030 γ amino-acid 5-methyltetrahydropteroyltriglutamate- a tRNA succinyldihydrolipoyl- bifunctional phosphorylase: 1,2-dimyristoyl- 1-palmitoyl-2- 1,2-dimyristoyl-IEK_RS16360 1-deoxy-D- C-terminal- - IEK_RS03000 IEK_RS04555 -dihydrolipoyl- carrier protein] histidinol transaminase: methionine UTP and CTP dephosphorylation I metallophosphatase/ deoD acyl-carrier protein sn-glycerol sn-glycerol xylulose 5- (5-phospho- diaminopimelate - homocysteine S- N-acetyl- L-lysine L-lysine acyl-carrier protein palmitoleoyl- L-arginino- IEK_RS18160 synthase: metH SAH 5'-nucleotidase: purine-nucleoside 3-phosphate 3-phosphate L-glutamyl)- ornithine ornithine epimerase: methyltransferase: IEK_RS07695 2-iminopropanoate gamma- sn-glycerol phosphate histidinol succinate branched-chain- L-tryptophan biosynthesis glutamyl- UTP IEK_RS11980 phosphorylase: 3-phosphate L-glutamate ArcD IEK_RS03765 methionine acetylglutamate 5'-methylthioadenosine/ dehydrogenase: hisD argininosuccinate amino-acid phosphate [+ 2 isozymes] IEK_RS07260 arg arg synthase: metH kinase: argB S-adenosylhomocysteine valine-- 2-oxoglutarate meso- lyase: argH transaminase: reductase: val CTP synthase: guanosine ornithine ornithine histidinal chorismate nucleosidase: mtnN tRNA ligase: dehydrogenase 1-palmitoyl- 1-myristoyl- 3-oxo-2-(cis- an [amino group carrier 1-palmitoyl- 4-(cytidine 5'- diaminopimelate argininosuccinate acetylglutamate IEK_RS01150 xanthine an apo [peptidyl- a cis- a uridine in tRNA RS22510 IEK_RS20020 met IEK_RS07035 IEK_RS05330 an L-valyl- E1 component: a (4Z)-hexadec-4-enoyl-[acp] a malonyl-[acp] coenzyme A sn-glycerol a palmitoleoyl-[acp] sn-glycerol sn-glycerol 3-phosphate 2'-pentenyl)- protein]-C-terminal-γ- sn-glycerol diphospho) lyase: IEK_RS10115 anthranilate pyruvate kinase: [+ 3 isozymes] CTP synthase: UMP purine-nucleoside carrier protein] vaccenoyl-[acp] dITP formate GTP biotin ATP histidinol diaminopimelate Val IEK_RS20735 3-phosphate 3-phosphate cyclopentane-1- (L-glutamyl)-L-glutamate 3-phosphate tRNA- -2-C-methyl- arg arg synthase: gln IEK_RS13450 N-acetyl-L-glutamate [tRNA ] IEK_RS15495 phosphorylase: 3-oxoacyl-[acyl-carrier- holo-ACP 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- glycerol-3-phosphate acetylglutamate 1-acyl-sn-glycerol- leu glu N-acetyl-L-glutamate S-ribosyl-L- Val XTP/dITP diphosphatase: anaerobic 4-(cytidine 5'- dehydrogenase: hisD decarboxylase: lysA 5-semialdehyde a tRNA dihydrolipoyllysine- bifunctional protein] reductase: synthase: 3-phosphate 3-phosphate 1-O-acyltransferase (3-oxohexanoyl) kinase: argB dihydrouridine D-erythritol biotin-- predicted arg IEK_RS20870 bifunctional acetylornithine homocysteine IEK_RS07260 acetyl-CoA C- IEK_RS05220 3-phosphate ribonucleoside- diphospho) residue metallophosphatase/ IEK_RS08480 IEK_RS25435 acyltransferase: acyltransferase: PlsY: IEK_RS09850 -CoA synthase: [acetyl-CoA- ABC glutamate N- carbamoyl- transaminase: CTP purine-nucleoside acyltransferase: nucleoside triphosphate acetylglutamate acyltransferase: triphosphate -2-C-methyl- glycine glycine his lys anthranilate PRPP succinyltransferase: 5'-nucleotidase: urate IEK_RS25595 IEK_RS25595 IEK_RS24925 carboxylase] transporter L-proline acetyltransferase/ phosphate IEK_RS07050 S-ribosylhomocysteine phosphorylase: deoD beta-ketoacyl-[acyl-carrier- 4'-phosphopantetheinyl glycerol-3-phosphate IEK_RS01120 kinase: IEK_RS25595 reductase: nrdD betaine betaine L-proline biosynthesis III IEK_RS11980 3-oxo-2-(cis- pyrophosphohydrolase: D-erythritol ligase: of glycine synthase: lyase: IEK_RS03735 IEK_RS20740 protein] synthase II: fabF transferase: 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-O-acyltransferase IEK_RS13450 1-acyl-sn-glycerol- tRNA biosynthesis I amino-acid bifunctional acetylornithine [+ 2 isozymes] IEK_RS00125 an [amino group carrier dGTP kinase: IEK_RS19330 IEK_RS08295 alanine-- [+ 2 isozymes] IEK_RS15795 3-phosphate 3-phosphate PlsY: IEK_RS15340 2'-pentenyl)- dihydrouridine biotinyl-5'- betaine anthranilate acetyltransferase glutamate N- aminotransferase: ala guanine acyl-carrier protein a (6Z)-3-oxooctadec-6-enoyl-[acp] α ω acetyl-CoA protein]-C-terminal- 3-phosphate 2-phospho-IEK_RS00180 tRNA ligase: CMP a holo [peptidyl- 1-C16:0- , -dicarboxyl- cyclopentane- dIMP synthase DusB: adenylate L-asparagine biosynthesis glu phosphoribosyltransferase: trpD glu ArgJ: IEK_RS07040 IEK_RS08300 acetyltransferase/ IEK_RS12410 L-homocysteine uridine 3',5'-ADP acyltransferase: acyltransferase: γ-(5-phospho-L- acyltransferase: 4-(cytidine 5'- IEK_RS05680 carrier protein] 2-lysophosphatidate 1-butanoyl-CoA IEK_RS00015 fluoride RS02355 fluoride III (tRNA-dependent) glutamate amino-acid an L-alanyl- bifunctional IEK_RS163601-palmitoyl-2- IEK_RS163601-myristoyl-2- glutamyl)-L-glutamate 1-palmitoyl-2-IEK_RS16360 a 5,6- diphospho) carbamoyl phosphate L-ornithine Ala L-alanine L-arginine 5-kinase: glutamate acetyltransferase [tRNA ] metallophosphatase/ acyl-carrier protein cis-vaccenoyl palmitoleoyl- cis-vaccenoyl dihydrouridine -2-C-methyl- N-(5-phosphoribosyl)-anthranilate Ala acyl-carrier protein biosynthesis I degradation I 5-kinase: ArgJ: IEK_RS07040 a tRNA 5'-nucleotidase: phosphatidate sn-glycerol phosphatidate in tRNA D-erythritol asp γ-L-glutamylIEK_RS12580 Glycolysis (arginase pathway) IEK_RS12580 N-acetyl-L-ornithine IEK_RS11980 3-phosphate fluoride RS02360 fluoride 3-methyl-2- 5-phosphate phosphoribosylanthranilate L-methionine biosynthesis III xanthine oxobutanoate aspartate-- isomerase: IEK_RS20850 γ-L-glutamyl L-cystathionine glycolysis I (from glucose 6-phosphate) [+ 2 isozymes] branched-chain- arg glutamate-5- 5-phosphate tRNA(Asn) 1-(2-carboxyphenylamino)-1- L-ornithine cytidine an apo-[LYS2 L- 1-cis-vaccenoyl- 1-stearoyl- a (1->4)- 1-palmitoyl- a cis,cis- a (1->4)- amino-acid arginase: rocF semialdehyde L-cysteine L-homoserine a nucleoside maltose ligase: deoxy-D-ribulose 5-phosphate ornithine cystathionine asparagine-- D-glucopyranose a malonyl-[acp] methyl ester a malonyl-[acp] 2-aminoadipyl- coenzyme A a cis- sn-glycerol- a palmitoyl-[acp] sn-glycerol a ribonucleic acid α-D-glucan sn-glycerol phosphoenol delta21,39-3- acetyl-CoA α-D-glucan a metal a metal transaminase: dehydrogenase: biosynthesis I homoserine O- asn triphosphate ser dGDP RS17785 arginase: rocF IEK_RS16470 glutamate-5- carbamoyltransferase: gamma- S-adenosyl-L-methionine cycle I tRNA ligase: 6-phosphate vaccenoyl-[acp] 3-phosphate alpha- maltose O- 3-phosphate 1,4-alpha- cation cation IEK_RS18160 indole-3-glycerol acetyltransferase: 3-oxoacyl-[acyl-carrier- carrier-protein] holo-ACP 1-acyl-sn-glycerol-3-phosphate 1-acyl-sn-glycerol- DNA- 1-acyl-sn-glycerol- pyruvate hydroxyC58:2- acetyl-CoA L-ornithine IEK_RS12585 semialdehyde ornithine argF synthase: IEK_RS04900 an L-asparaginyl- urate glucosidase: L-serine ammonia-lyase, acetyltransferase: pyruvate glucan an L-aspartyl- phosphate synthase IEK_RS04030 glucose-6- protein] reductase: synthase: 3-phosphate 3-phosphate directed RNA 3-phosphate [acp] 3-oxoacyl-ACP carboxylase branched-chain- L-glutamate-5- ser dehydrogenase: aminotransferase: O-acetyl-L- IEK_RS05760 [tRNA Asn ] IEK_RS24695 iron-sulfur-dependent, IEK_RS04385 kinase: pyk branching [tRNA Asn ] TrpC: IEK_RS20855 hydrogen sulfide S-methyl-5'-thioadenosine IEK_RS08480 IEK_RS25435 reductase: biotin carboxyl: serine O- L-threonine SAM Asn phosphate acyltransferase: acyltransferase: polymerase subunit beta: sdaAB acyltransferase: amino-acid ornithine semialdehyde IEK_RS12585 IEK_RS21285 homoserine cystathionine tRNA alpha- maltose O- pyruvate IEK_RS10510 IEK_RS15050 protein GlgB: a metal a metal transaminase: acetyltransferase: biosynthesis isomerase: degradation IV beta-ketoacyl-[acyl-carrier- 4'-phosphopantetheinyl IEK_RS25595 IEK_RS25595 subunit alpha: IEK_RS25595 cation cation aminotransferase: gln Asp-tRNA(Asn) (1S,2R)-1-C-(indol-3- O-acetylhomoserine gamma- glucosidase: L-serine ammonia-lyase, acetyltransferase: kinase: IEK_RS15055 IEK_RS03350 cysE IEK_RS03185 protein] synthase II: fabF transferase: IEK_RS25940 a cis,cis-[+ 4 isozymes] α RS02430 IEK_RS20020 IEK_RS21285 /Glu-tRNA(Gln) yl)glycerol 3-phosphate aminocarboxypropyltransferase: synthase: S-methyl-5'- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- IEK_RS07635 iron-sulfur-dependent, IEK_RS11040 1-acyl-sn-glycerol- IEK_RS11150 a (1,6)- -D- O-acetyl-L-serine L-glutamate-5- S-adenosylmethionine purine ribonucleosides degradation IEK_RS15795 delta21,39-3- [+ 4 isozymes] ala ala val amidotransferase IEK_RS00825 L-homoserine IEK_RS06325 thioadenosine acyl-carrier protein a 3-oxoglutaryl-[acp] methyl ester a holo-[LYS2 L- 3-phosphate 3-phosphate [+ 3 isozymes] a (1->4)- subunit beta: sdaAB 6-O-acetyl-α-D- 3-phosphate glucosyl-(1,4) L-glutamate-5- CTP synthase: tryptophan synthase: semialdehyde F6P 5'-methylthioadenosine/ D-glucopyranose dGTP pyruvate oxo-C58:2-[acp] malonyl-CoA subunit GatA: (S)-1-pyrroline- L-citrulline homoserine synthase: IEK_RS03865 aspartate-- 2-aminoadipyl- 3',5'-ADP acyltransferase: acyltransferase: a ribonucleic acid α-D-glucan pyruvate glucopyranosyl- acyltransferase: -α-glucan a metal a metal semialdehyde IEK_RS15495 cysteine IEK_RS20840 trpB S-adenosylhomocysteine RS18995 IEK_RS24995 5-carboxylate L-homocysteine kinase: cys tRNA ligase: carrier-protein] IEK_RS163601,2-dicis- IEK_RS163601-stearoyl- (1->4)-D-glucose 1-palmitoyl-IEK_RS16360 cation cation [+ 13 isozymes] synthase A: cysK tryptophan synthase nucleosidase: mtnN adenosine L-glutamate a 4-phosphooxy- argininosuccinate IEK_RS17450 IEK_RS05610 fructose- acyl-carrier protein vaccenoyl- 2-myristoyl pyrroline-5- subunit beta: trpB O-phospho- met SAH [+ 4 isozymes] 2-palmitoyl- gamma- L-aspartyl- [+ 2 isozymes] 5-methyltetrahydropteroyltriglutamate- synthase: bisphosphatase acyl-carrier protein ammonium carboxylate L-homoserine aspartate-- MTR phosphatidate sn-glycerol phosphatidate semialdehyde [tRNA Asn ] (S)-1-pyrroline- - homocysteine S- methionine IEK_RS04555 5'-methylthioadenosine/ class II: glpX reductase: cys tRNA(Asn) 6-phosphofructokinase: 3-phosphate a metal a metal ala dehydrogenase: ser indole 5-carboxylate threonine S-adenosylhomocysteine asp RS02495 IEK_RS25640 methyltransferase: IEK_RS07695 synthase: 5-methyltetrahydropteroyltriglutamate- fructose- pfkA cation cation pruA Asp-tRNA(Asn) pyrroline-5- L-arginino-succinate synthase: nucleosidase: mtnN ligase: alanine methionine metH - homocysteine S- bisphosphatase /Glu-tRNA(Gln) [+ 2 isozymes] tryptophan synthase IEK_RS17455 [+ 3 isozymes] IEK_RS16470 an L-aspartyl- 1-palmitoyl- 1-stearoyl- a carboxy- (25S)-3- 1-oleoyl-sn a cis,cis- carboxylate synthase: class II: glpX [EntB aryl- racemase: alr glu argininosuccinate methyltransferase: IEK_RS07695 [tRNA asp ] a palmitoyl-[acp] a malonyl-[acp] coenzyme A a palmitoyl-[acp] sn-glycerol a stearoyl-[acp] sn-glycerol glycerophosphoserine oxocholest- coenzyme A -glycerol 3- phosphoenol delta19,37- roseoflavin amidotransferase subunit beta: trpB reductase: xanthosine adenosine inosine guanosine carrier protein] cys adenylated-[ThiS XTP dADP ATP dIDP a metal a metal alanine pro metH lyase: argH thr methionine synthase: metH tRNA asp 3-phosphate 3-phosphate 4-en-26-oate phosphate pyruvate 3-hydroxy- 5'-phosphate RS03975 subunit GatA: IEK_RS25640 L-homocysteine S-ribosyl-L-homocysteine β-D-fructose 1,6- 3-oxoacyl-[acyl-carrier- holo-ACP 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- glycerophosphoryl sulfur-carriercysteine protein] acyl-CoA 1-acyl-sn-glycerol- cation cation racemase: alr superpathway of L- argininosuccinate DHAP diester XTP/dITP diphosphatase: synthetase: pyruvate C56:2-[acp]3-oxoacyl-ACP bifunctional nucleoside- IEK_RS24995 trp [+ 2 isozymes] met bisphosphate protein] reductase: synthase: 3-phosphate 3-phosphate desulfurase: 3-phosphate asparagine biosynthesis lyase: IEK_RS10115 IEK_RS05220 kinase: pyk reductase: riboflavin diphosphate purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside IEK_RS08480 IEK_RS25435 acyltransferase: acyltransferase: phosphodiesterase: IEK_RS05635 IEK_RS17385 acyltransferase: D-ala fructose-1,6- nucleoside triphosphate pyruvate IEK_RS10510 kinase/FAD kinase: an L-asparaginyl- pro phosphorylase: phosphorylase: phosphorylase: phosphorylase: beta-ketoacyl-[acyl-carrier- 4'-phosphopantetheinyl IEK_RS25595 IEK_RS25595 IEK_RS23805 [+ 2 isozymes] acyl-CoA IEK_RS25595 arg tyrosine-- triose- bisphosphate pyrophosphohydrolase: kinase: synthetase: IEK_RS19440 a sugar RS07650 a sugar [tRNA Asn ] asp S-ribosylhomocysteine deoD IEK_RS07260 IEK_RS07260 IEK_RS07260 protein] synthase II: fabF transferase: [+ 4 isozymes] synthetase: a cis,cis-[+ 4 isozymes] L-alanine aldolase, 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- a thiocarboxy- IEK_RS00125 1-acyl-sn-glycerol- IEK_RS11150 L-ornithine degradation lyase: IEK_RS03735 tRNA ligase: phosphate sn-glycerol AMP ala IEK_RS09740 delta19,37-3- ribF dITP class II: fba purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside acyl-carrier protein a 3-oxooctadecanoyl-[acp] IEK_RS15795 3-phosphate 3-phosphate ser [ThiS-Protein] (25S)-3- roseoflavin adenine biosynthesis III I (L-proline biosynthesis) IEK_RS02385 isomerase: a holo-[EntB aryl- 3-phosphate XMP 3-phosphate dATP pyruvate oxo-C56:2-[acp] glycine biosynthesis I pyrimidine deoxyribonucleotides phosphorylase: phosphorylase: phosphorylase: phosphorylase: 3',5'-ADP acyltransferase: acyltransferase: oxocholest-4- acyltransferase: dinucleotide asparagine asparagine tyrosine-- IEK_RS02200 carrier protein] a sugar RS27515 a sugar tyr dephosphorylation IEK_RS07260 deoD deoD deoD IEK_RS16360 IEK_RS16360 en-26-oyl-CoA IEK_RS16360 cys synthetase B: synthase (glutamine- tRNA ligase: 1-stearoyl-2- cys L-ornithine nucleoside triphosphate dipalmitoyl dioleoyl cys RS30905 cysteine IEK_RS09390 hydrolyzing): asnB ser acyl-carrier protein stearoyl-sn ornithine IEK_RS04405 an L-tyrosyl- D-glyceraldehyde pyrophosphohydrolase: α-D-ribose- phosphatidate acyl-carrier protein phosphatidate desulfurase: -glycerol 3- cyclodeaminase: [+ 3 isozymes] [+ 4 isozymes] serine [tRNA Tyr ] 3-phosphate IEK_RS00125 1-phosphate phosphate a sugar RS23445 a sugar IEK_RS02790 IEK_RS22325 hydroxymethyltransferase: a tRNA Tyr dCTP dCMP glyceraldehyde- pyrimidine C1 Compound Utilization thiamine ThiT thiamine [+ 2 isozymes] pro IEK_RS01260 phosphopentomutase: 3-phosphate ribonucleosides deoB and Assimilation ala asn asn gly 1-palmitoyl- 3-oxo-2-(cis- α a cis,cis- dehydrogenase: dUTP diphosphatase: degradation AsbD acyl- 1,4-dihydroxy- a [protein] N-terminal- a [protein]- - D-ribose 5- formate assimilation into 5,10- an acyl-[acyl-carrier protein] a malonyl-[acp] coenzyme A sn-glycerol a myristoyl-[acp] GGPP oleate 2'-pentenyl)- β-alanine delta17,35-3- DHAP a sugar RS12665 a sugar gap IEK_RS29005 cytidine carrier protein 2-naphthoate formyl-L-methionine L-glutamate IMP IDP tryptophan- phosphate methylenetetrahydrofolate 3-phosphate acyl-CoA cyclopentane-1- peptide protein-glutamate O- hydroxyC54:2- glycerol-3- cytidine deaminase: beta-ketoacyl-[acyl-carrier- holo-ACP 1-acyl-sn-glycerol- 1,4-dihydroxy- 4-aminobutyrate- predicted nucleoside triphosphate synthetase: deformylase: methyltransferase bifunctional [acp] phosphate nucleoside- -tRNA IEK_RS17965 protein] synthase II: fabF synthase: 3-phosphate 2-naphthoate (3-oxobutanoyl) 3-oxoacyl-ACP ABC efflux 13-DPG pyrophosphohydrolase: S-methyl-5'-thioadenosine formate IEK_RS09740 IEK_RS07845 CheR: IEK_RS18880 -2-oxoglutarate metallophosphatase/ diphosphate ligase: trpS 3-oxoacyl-[acyl-carrier- IEK_RS25435 acyltransferase: polyprenyltransferase: -CoA acetyl-CoA C- reductase: dehydrogenase a sugar RS00130 a sugar thiol transporter thiol IEK_RS00125 cytidine deaminase: degradation III transaminase: 5'-nucleotidase: kinase: tryptophan-- dUTP dUMP formate--tetrahydrofolate protein] reductase: IEK_RS25595 IEK_RS11830 [+ 4 isozymes] acyltransferase: peptide protein-glutamate O- IEK_RS10510 (NAD(P)(+)): of a thiol Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Trp IEK_RS06105 4'-phosphopantetheinyl gabT a tRNA ligase: IEK_RS16805 IEK_RS01120 deformylase: methyltransferase IEK_RS11980 a cis,cis-[+ 4 isozymes] IEK_RS19490 IEK_RS19440 group tRNA ligase: uridine S-methyl-5'- IEK_RS08480 transferase: 1-acyl-sn-glycerol- 1,4-dihydroxy- phosphoglycerate 10 diphosphate AMP oleoyl-CoA CheR: IEK_RS21865 4-aminobutyrate- [+ 2 isozymes] delta17,35-3- sn-glycerol IEK_RS11035 an L-tryptophanyl- thioadenosine an N -formyltetrahydrofolate IEK_RS15795 3-phosphate (+)-7-[+ 2 isozymes]epi- IEK_RS08395 a [protein]-L- ITP [2Fe-2S] iron-sulfur cluster biosynthesis kinase: pgk pyrimidine-nucleoside 5-methylthioadenosine/S- acyl-carrier protein a 3-oxoacyl-[acp] 2-naphthoate acetyl-CoA an N-terminal L- -2-oxoglutarate inosine oxo-C54:2-[acp] 3-phosphate predicted predicted superpathway of menaquinol-7 biosynthesis superpathway of thiamine diphosphate biosynthesis II Trp 5-hydroxy-CTP 5-hydroxy-CMP a holo-[AsbD acyl- jasmonoyl-CoA formate 5 superpathway of tetrahydrofolate biosynthesis thiamine salvage III menaquinol-6 biosynthesis thiamine salvage II [tRNA ] phosphorylase: deoA adenosylhomocysteine bifunctional 3',5'-ADP acyltransferase: polyprenyltransferase: methionyl-[protein] glutamate-O transaminase: ABC ABC carrier protein] a sugar a sugar D-ribose D-ribose trp deaminase: IEK_RS18085 methylenetetrahydrofolate IEK_RS163601-palmitoyl- IEK_RS03400 -methyl-ester IEK_RS24975 transporter transporter 4-amino-2-methyl-5- 3-phospho- pyrimidine-nucleoside S-methyl-5'- L-cysteine desulfurase chorismate thiamine demethylmenaquinol-6 dehydrogenase/ acyl-carrier protein 2-myristoyl demethylmenaquinol-4 3-oxopropanoate of a sugar of D-ribose cys pyrimidinemethanol D-glycerate phosphorylase: deoA thioinosine GTP thiamine demethylmenaquinone a ThiS sulfur- methenyltetrahydrofolate phosphatidate cysteine isochorismate carrier protein bifunctional uracil formate formate diphosphokinase: methyltransferase: cysteine 2,3- cyclohydrolase: IEK_RS06795 a sugar RS22965 a sugar synthase EntC: threonine-- 2,3-bisphosphoglycerate- desulfurase: GTP IEK_RS08435 IEK_RS19450 hydroxymethylpyrimidine diphosphoglycerate- RS16830 desulfurase: ThiS a glycopeptide- all-trans- 34 a cis,cis- IEK_RS02790 IEK_RS15825 cyclohydrolase thiamine menaquinol-6 kinase/ tRNA ligase: independent a 5,10-methenyltetrahydrofolate 1,4-dihydroxy- carbamoyl a guanine 3-amino-4- N-acetyl- (S)-1-pyrroline- DNA with lesion oxalate oxalate IEK_RS02790 adenylyltransferase: dependent an acetyl-[acp] a malonyl-[acp] D-mannosyl-N 4 undecaprenyl a purine asp queuine delta15,33- [+ 2 isozymes] isochorismate diphosphate phosphomethylpyrimidine IEK_RS15735 phosphoglycerate 5-MTR-1-P 2-naphthoate arsenate in tRNA hydroxybenzaldehyde ITP L-citrulline 5-carboxylate IMP I FolE: folE [+ 2 isozymes] thiF phosphoglycerate -(N-acetyl-D- diphosphate ribonucleoside phosphate tRNA arylamine N- L-glutamate excinuclease a sugar RS23925 a sugar nitrate RS16675 nitrate synthase: kinase: thiD mutase: IEK_RS02205 bifunctional 3-oxoacyl-[acyl-carrier- 1,4-dihydroxy- aspartate acetylornithine 3-hydroxy an S-sulfanyl-[L- GTP an [L-cysteine a carboxy- threonine-- mutase: gpmA purine-nucleoside XTP/dITP diphosphatase: gamma- thr methylenetetrahydrofolate protein] reductase: glucosaminyl) 2-naphthoate carbamoyltransferase guanosine(34) acetyltransferase: deacetylase: C52:2-[acp]3-oxoacyl-ACP ABC subunit GMP IEK_RS03405 desulfurase]-S- adenylated-[ThiS bifunctional tRNA ligase: mannosyl-glycoprotein phosphorylase: IEK_RS05220 semialdehyde cysteine desulfurase] cyclohydrolase dehydrogenase/ IEK_RS08480 -asparagine transglycosylase IEK_RS10405 IEK_RS16090 reductase: UvrA: reductase: sulfanyl-L-cysteine sulfur-carrier protein] hydroxymethylpyrimidine IEK_RS04820 2-phospho- 2 endo-beta-N- polyprenyltransferase: deoD catalytic subunit: isochorismate I FolE: folE D-glyceraldehyde an L-threonyl- methenyltetrahydrofolate Tgt: tgt arylamine N- nucleoside triphosphate dehydrogenase: IEK_RS10510 IEK_RS14890 3+ 3+ Thr beta-ketoacyl-[acyl-carrier- IEK_RS11830 IEK_RS08285 acetylornithine guaC Fe RS05055 Fe 7,8- 3-phosphate kinase/ [tRNA ] D-glycerate acetylglucosamidase: purine-nucleoside pyrophosphohydrolase: pruA his RS12065 his cyclohydrolase: IEK_RS06795 a glycopeptide- N-carbamoyl- 34 acetyltransferase: a cis,cis-[+ 4 isozymes] [+ 2 isozymes] dihydroneopterin cysteine phosphomethylpyrimidine a tRNA Thr protein] synthase II: fabF N-acetyl-D-IEK_RS24540 1,4-dihydroxy- a queuosine deacetylase: 2-succinyl-5- 1-deoxy-D- gly D-mannosyl- phosphorylase: L-aspartate guanine IEK_RS13920 IEK_RS00125 delta15,33-3- DNA without GMP an S-sulfanyl-[cysteine 3'-triphosphate AIR desulfurase: kinase: thiD enolase: an acetoacetyl-[acp] acyl-carrier protein glucosamine- 2-naphthoate in tRNA IEK_RS24365 glu enolpyruvyl- xylulose-5- a 5,10-methylenetetrahydrofolate N 4 -N-acetyl- IEK_RS07260 3-acetylamino-4- IMP oxo-C52:2-[acp] lesion desulfurase]-[disordered- IEK_RS02790 IEK_RS02210 asparagine polyprenyltransferase: hydroxybenzaldehyde acetate L-citrulline L-cystine RS06380 L-cystine 6-hydroxy-3- phosphomethylpyrimidine phosphate glycine D-glucosamine ribose-1-arsenate a purine base met RS02760 met form scaffold [+ 2 isozymes] HMP-P 5-(2-hydroxyethyl) IEK_RS03400 cyclohexene- flavin biosynthesis I (bacteria and plants) synthase ThiC: synthase: oxidase protein] complex -4-methylthiazole DMKH2-11 1-carboxylic- 7,8- IEK_RS06815 ThiO: thiO serine-- Secondary Metabolite Degradation [cysteine desulfurase]-S- IEK_RS01760 bifunctional hydroxyethylthiazole ser phosphoenol acid synthase: dihydroneopterin a thiocarboxy- tRNA ligase: phosphonate phosphonate sulfanylcysteine:[acceptor 1-deoxy-D-xylulose hydroxymethylpyrimidine kinase: IEK_RS24670 pyruvate met RS25745 met RS09460 IEK_RS03410 3'-phosphate HMP-P [ThiS-Protein] 2-iminoacetate IEK_RS00325 phosphite phosphite protein]-cysteine GTP 5-phosphate kinase/ an L-seryl- anhydromuropeptides recycling I 4-methyl-5(B- ser D-fructuronate degradation undecaprenyl-diphospho-N an odd numbered all-trans- a plant soluble a [lipoyl-carrier a cis,cis- sulfurtransferase: phosphomethylpyrimidine [tRNA ] pyruvate 1,4-dihydroxy- a (6S)-5- a ribonucleoside D-gluconate an organic a [protein]-L- 2-succinyl-6- bifunctional a uracil in DNA 6 chorismate hydroxyethyl) ser -acetylmuramoyl-L-alanyl-γ- UDP-N-acetyl-α-D-glucosamine straight chain dodecaprenyl glu heteroglycan 6-phosphate met protein]-N -[(R) delta13,31- hydroperoxide methionine IEK_RS05635 hydroxy-2, 4- thiazole kinase: thiD a tRNA kinase: pyk GlcNAc-1,6- 2-naphthoate formyltetrahydrofolate 5'-monophosphate bifunctional hydroxymethylpyrimidine -thiazole phosphoenolpyruvate D-fructuronate D-glutamyl-L-lysyl- D-alanine 2,3,4-saturated diphosphate glycogen/starch/ 6-phosphogluconate uracil-DNA -dihydrolipoyl]- 3-hydroxy alkyl peptide- a sugar 6- a [cysteine desulfurase]- cyclohexadiene- synthase: pyruvate anhMurNAc- undecaprenyldiphospho- 1,4-dihydroxy- bifunctional bifunctional bifunctional predicted a sugar RS02720 7,8- aminodeoxychorismate/ 3,4-dihydroxy- kinase/ bifunctional monophosphate synthase: IEK_RS12015 γ mannonate fatty acidacyl-CoA alpha-glucan dehydrogenase glycosylase: L-lysine dihydrolipoyl C50:2-[acp]3-oxoacyl-ACP hydroperoxide methionine phosphate S-sulfanyl-[disordered- 1-carboxylate IEK_RS23045 kinase: L-Ala- -D-Glu- muramoylpentapeptide beta-N- 2-naphthoate folylpolyglutamate metallophosphatase/ glutamate N- ABC dihydroneopterin anthranilate 2-butanone-4- phosphomethylpyrimidine hydroxymethylpyrimidine biosynthesis oxidoreductase: synthetase: phosphorylase: (decarboxylating): gnd IEK_RS19370 dehydrogenase: reductase: reductase (S)-S-oxide form scaffold synthase: menH IEK_RS11150 DAP-D-Ala acetylglucosaminyltransferase: polyprenyltransferase: synthase/ 5'-nucleotidase: acetyltransferase/ met transporter met dihydroneopterin synthase component phosphate synthase/ kinase: thiD thiamine formation from kinase/ protein: IEK_RS10415 IEK_RS09740 IEK_RS03370 6-phosphogluconate uracil-DNA lpdA IEK_RS10510 subunit F: reductase: protein] complex 2-[(2R,5Z)-2-carboxy- proline-- IEK_RS06345 an odd numbered IEK_RS11830 dihydrofolate α-D- IEK_RS02805 amino-acid of L- cysteine 2-succinyl-5- II: IEK_RS00045 GTP cyclohydrolase phosphomethylpyrimidine [+ 4 isozymes] a plant soluble a [lipoyl-carrier a cis,cis- IEK_RS24870 msrA aldolase: folB bifunctional 4-methylthiazol-5(2H)- pyrithiamine and oxythiamine (yeast) IEK_RS09615 tRNA ligase: D-mannonate [+ 2 isozymes] synthase: glucopyranose [+ 2 isozymes] dehydrogenase glycosylase: acetyltransferase [+ 2 isozymes] [+ 4 isozymes] a protein-L- methionine predicted desulfurase: enolpyruvoyl-6- II: IEK_RS07135 kinase: thiD pyruvate ditrans,octacis-undecaprenyldiphospho- straight chain 1,4-dihydroxy- heteroglycan 6 4-amino-4- hydroxymethylpyrimidine ylidene]ethyl phosphate 4-methyl-5-(2- diphosphate AMP IEK_RS05335 1-phosphate (decarboxylating): gnd IEK_RS00865 ArgJ: IEK_RS07040 protein]-N - delta13,31-3- an alcohol methionine- PEP-driven a sugar 6- IEK_RS02790 hydroxy-3-cyclohexene- 6-(hydroxymethyl) IEK_RS24560 Macromolecule Modification UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- 2,3,4-saturated 2-naphthoate a ribonucleoside D-ribulose an apyrimidinic met met a sugar deoxychorismate 2,5-diamino-6-(5-phospho-D- kinase/ pyrithiamine phosphooxyethyl) N-acetyl-β-D- L-alanyl-γ-D- a (6S)-5- uracil N-acetyl-L- lipoyl-L-lysine oxo-C50:2-[acp] RS07340 transporter phosphate 1-carboxylate -7,8-dihydropterin HMP-PP proline-- L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine fatty acyl CoA polyprenyltransferase: 5-phosphate site in DNA (S)-S-oxide ala ala [+ 2 isozymes] 4-amino-4- ribosylamino)pyrimidin-4(3H)-one phosphomethylpyrimidine thiazole pro glucosamine-1,6- glutamyl-meso-2,6- formyltetrahydrofolate methionine of a sugar an S-sulfanyl-[cysteine 2-succinyl-6- 2-amino-4-hydroxy-6- tRNA ligase: IEK_RS03400 thiaminase queuosine biosynthesis anhydro-N-acetyl- 2-dehydro-3- desulfurase]-S- deoxychorismate bifunctional kinase: thiD diaminopimeloyl- hydroxy-2, 4- hydroxymethyldihydropteridine 2-(2-carboxy-4- II: tenA heme a biosynthesis IEK_RS08640 an L-prolyl- β DMK-12 lyase: diaminohydroxyphosphoribosylaminopyrimidine thiamine -D-muramate D-alanine deoxy-D-gluconate predicted sulfanyl-[disordered- cyclohexadiene- diphosphokinase: folK methylthiazol-5- [tRNA Pro ] IEK_RS00040 HMP-PP thiaminase phosphate LD- ala RS15755 ala PEP-driven a sugar 6- form scaffold 1-carboxylate (7,8-dihydropterin- deaminase/5-amino-6-(5-phosphoribosylamino) yl)ethyl phosphate a tRNA Pro preQ II: tenA 0 carboxypeptidase: a sugar uracil reductase RibD: ribD synthase: protoheme transporter phosphate protein] complex synthase: menH 6-yl)methyl 4-aminobenzoate protoheme IX NADPH- decaprenyl-diphospho-N- UDP-N-acetyl- an all-trans- a 2'- a cis,cis- a (5Z)-3- a protein-L- [cysteine desulfurase]-S- 4-amino-2-methyl-5- IEK_RS23060 IEK_RS17545 (15Z)- 1,4-dihydroxy- 7,8-dihydrofolate + maltohexaose a [ThiI sulfur-carrier a cis,cis-delta5,17-3- of a sugar (1R,6R)-6-hydroxy-2- diphosphate 5-amino-6-(5-phospho- thiamine dependent α polyisoprenyl NADPH H deoxyribonucleoside [DNA] 2-phosphoglycolate oxododec- methionine- sulfanylcysteine:[acceptor pyrimidinemethanol farnesyltransferase: 1,6-anhydro-N- [+ 2 isozymes] acetylmuramoyl-pentapeptide -D-glucosamine tetracosenoate 2-naphthoate monoglutamate cys AMP delta11,29- succinylcyclohexa-2,4- D-ribosylamino)uracil phosphate thiamine 7-cyano-7- β KDGP undecaprenyldiphospho- glycogen/starch/ protein]-L-cysteine hydroxyC36:2[acp] gln RS23555 gln protein]-cysteine IEK_RS08005 acetyl- -muramate L-alanyl-γ-D- acyl-CoA diphosphate dihydrofolate cysteine 5'-triphosphate DNA phosphoglycolate 3-oxoacyl-ACP 3-hydroxy 5-enoyl-[acp]3-oxoacyl-ACP (R)-S-oxide diene-1-carboxylate bifunctional phosphate deazaguanine 1,4-dihydroxy- peptide- predicted bifunctional synthase: ferroheme o phenylalanine- glutamyl-meso- muramoylpentapeptide beta-N- synthetase: reductase: alpha-glucan desulfurase: phosphatase: bifunctional reductase: C48:2-[acp]3-oxoacyl-ACP reductase: sulfurtransferase: D-ribulose 5-phosphate hydroxymethylpyrimidine synthase: anhydro-N- 2-naphthoate polymerase III: methionine PEP-driven a sugar 6- o-succinylbenzoate diaminohydroxyphosphoribosylaminopyrimidine IEK_RS23060 -tRNA ligase: reductase QueF: diaminopimelate acetylglucosaminyltransferase: IEK_RS17385 IEK_RS23510 phosphorylase: IEK_RS16445 metallophosphatase/ reductase: a sugar IEK_RS05635 kinase/ phe acetylmuramic polyprenyltransferase: IEK_RS05635 IEK_RS00250 IEK_RS10510 IEK_RS04105 (R)-S-oxide transporter phosphate a [cysteine synthase: menC 7,8- IEK_RS24665 IEK_RS20315 IEK_RS06345 IEK_RS03370 5'-nucleotidase: acetate acetate bifunctional deaminase/5-amino-6-(5-phosphoribosylamino) thiamine heme A synthase: IEK_RS04890 acid kinase: D-glyceraldehyde [+ 4 isozymes] IEK_RS03400 dihydrofolate α-D- [+ 2 isozymes] IEK_RS00290 phosphoglycolate [+ 4 isozymes] IEK_RS10510 [+ 3 isozymes] reductase: desulfurase]-(S- dihydropteroate phosphomethylpyrimidine preQ myo-inositol degradation I a [ThiI sulfur- IEK_RS11980 a cis,cis- a (3R,5Z)-3- of a sugar 3,4-dihydroxy- uracil reductase RibD: ribD phosphate IEK_RS08000 IEK_RS04895 an L-phenylalanyl- 1 IEK_RS15350 pyruvate [+ 2 isozymes] reductase: phosphatase: a cis,cis-[+ 4 isozymes] RS19010 sulfanyl) -[disordered- 2-succinylbenzoate kinase: thiD 3-phosphate decaprenyl-pyrophosphoryl- (15Z)- 1,4-dihydroxy- glucopyranose maltopentaose carrier protein]-S- ala [+ 7 isozymes] delta5,17-3- hydroxydodec- IEK_RS00670 a metal a metal 2 synthase: thiamine Phe N-acetyl-D- AMP diphosphate IEK_RS16375 IEK_RS12475 [+ 2 isozymes] delta11,29-3- a [protein]-L- bifunctional 2-butanone-4- 5-amino-6-(5-phospho- [tRNA ] tRNA UDP (N-acetylglucosamine)-N- tetracosenoyl-CoA 1-phosphate sulfanyl-L-cysteine [DNA] oxo-C36:2-[acp] 5-enoyl-[acp] form scaffold oxythiamine bifunctional phosphate ferroheme i Phe 2-naphthoate 5,6,7,8- cation cation predicted folylpolyglutamate IEK_RS24665 a tRNA muramate 6- myo-inositol + adenosine oxo-C48:2-[acp] methionine formate formate phosphate synthase/ D-ribitylamino)uracil guanosine(34) acetylmuramyl-(pentapeptide) polyprenyltransferase: NADP glycolate RS10020 ABC protein] complex o-succinylbenzoate- hydroxymethylpyrimidine phosphate tetrahydrofolate nitrite nitrite acetoin acetoin synthase/ GTP cyclohydrolase thiaminase transglycosylase (2E,6E)-farnesyl -CoA ligase: menE kinase/ heme A synthase: N-acetylmuramic inositol 2- IEK_RS11830 transporter IPP dihydrofolate II: IEK_RS07135 II: tenA Tgt: tgt diphosphate thiamine phosphate phosphomethylpyrimidine IEK_RS08000 dehydrogenase: DMKH of acetoin 4-(2'-carboxyphenyl) synthase: a 7-aminomethyl-7- acid 6- myo-, chiro- and scyllo-inositol degradation 2 1-deoxy-L-glycero- thiaminase kinase: thiD iolG a [cysteine desulfurase]- heptaprenyl -4-oxobutyryl-CoA IEK_RS05335 thiamine 34 phosphate formate formate ARP II: tenA hydroxyferroheme i methionine-- deazaguanosine RS20495 an aliphatic an aliphatic tetrulose 4-phosphate lipoate biosynthesis diphosphate etherase: murQ nitrite nitrite RS12950 [scaffold protein- diphosphate 1,4-dihydroxy- 7,8-dihydrofolate tRNA ligase: in tRNA scyllo-inosose sulfonate sulfonate and incorporation II 5-(2-hydroxyethyl) HMP-P N-acetyl-D- 1D-chiro-inositol ditrans,octacis- all-trans- an N-hydroxy- a 3- a cis,cis- a (9Z)-3- (2Fe-2S)] complex synthase 2-naphthoyl- monoglutamate IEK_RS00215 tRNA preQ1(34) S- 1,4-dihydroxy- a maltodextrin a D-aminoacyl- a ribonucleoside roseoflavin -4-methylthiazole glucosamine a peptidoglycan with undecaprenyldiphospho- O-succinyl-L-homoserine tridecaprenyl MEP CTP arylamine 3'-AMP oxodocosanoyl- delta19,31-3- oxooctacos- component CoA synthase: 6,7-dimethyl-8- bifunctional methionine-- adenosylmethionine myo-inosose-2 2-naphthoate [tRNA] 3'-phosphate thiamine diphosphate octanoate hydroxyethylthiazole met 6-phosphate (L-alanyl-γ-D-glutamyl- N-acetyl-(N-acetyl-β-D- cystathionine gamma- diphosphate glycogen/starch/ bifunctional 2',3'- arylamine N- bifunctional 2',3'- [acp] hydroxyC50:2- 9-enoyl-[acp]3-oxoacyl-ACP bifunctional asp asp II: hepT IEK_RS03420 ribityllumazine hydroxymethylpyrimidine tRNA ligase: ribosyltransferase- dehydratase: iolE 1,4-dihydroxy- 2-C-methyl-D- D-aminoacyl- 3-oxoacyl-ACP lipoate--protein kinase: IEK_RS24670 N-acetylglucosamine- myo-inositol L-lysyl-D-alanyl-D- glucosaminyl)muramoyl- alpha-glucan acetyltransferase: cyclic-nucleotide 2'- [acp] 3-oxoacyl-ACP riboflavin chloride RS00820 chloride synthase: kinase/ ferroheme a an L-methionyl- 3D-(3,5/4)- synthase: IEK_RS05760 2-naphthoate erythritol 4-phosphate tRNA cyclic-nucleotide 2'- reductase: reductase: RS19845 a [co-chaperone]- heptaprenyl 1,4-dihydroxy-2- IEK_RS02545 isomerase QueA: 1-keto-D- alanine) pentapeptide γ phosphorylase: IEK_RS10405 kinase/FAD IEK_RS07130 ligase A: 4-methyl-5(B- [elongator 6-phosphate trihydroxycyclohexane- L-alanyl-peptidoglycan-D-glutamyl-L- cystathionine gamma- polyprenyltransferase: cytidylyltransferase: deacylase: phosphodiesterase/ phosphodiesterase/ IEK_RS10510 reductase: IEK_RS10510 glutamate [scaffold protein- diphosphate naphthoyl-CoA a 7,8-dihydrofolate phosphomethylpyrimidine IEK_RS05525 scyllo-inositol IEK_RS03370 synthetase: glutamate IEK_RS21505 hydroxyethyl) elongator Met deacetylase: nagA chiro-inositol lysyl-D-alanyl-D-alanine α 3'-nucleotidase: arylamine N- 3'-nucleotidase: IEK_RS10510 a [lipoyl-carrier protein] kinase: thiD tRNA ] 34 1,2-dione inositol 2- a peptidoglycan with transglycosylase: synthase: IEK_RS06325 IEK_RS11830 IEK_RS26195 -D- IEK_RS05585 a (3R)-3-[+ 4 isozymes] a cis-delta9-3-[+ 4 isozymes] D-gluconate RS28490 D-gluconate (2Fe-2S)] complex synthase: Met an epoxyqueuosine ribF 6 -thiazole tRNA D-glucosamine di-trans,octa-cis an uncharged IEK_RS07080 acetyltransferase: IEK_RS07080 a cis,cis-[+ 4 isozymes] SSQ1 IEK_RS19455 dihydrofolate 6,7-dimethyl-8-(1-D-ribityl)lumazine N -octanoyl-L-lysine 3D-(3,5/4)- dehydrogenase: (L-alanyl-γ-D-glutamyl- IEK_RS24040 succinate L-homocysteine 1,4-dihydroxy- hypothetical protein: glucopyranose a maltodextrin a D-amino acid hydroxydocosanoyl- hydroxyC28:1- predicted ABC N 10 -formyl-tetrahydrofolate biosynthesis bifunctional thiamine salvage IV (yeast) in tRNA -undecaprenyl tRNA IEK_RS13920 delta19,31-3- roseoflavin reductase: monophosphate 6-phosphate iolG L-lysyl-D-alanyl-D- 2-naphthoate 1-phosphate a ribonucleoside [acp] [acp] daunorubicin transporter of daunorubicin chaperone: lipoyl hydroxymethylpyrimidine trihydroxycyclohexane- IEK_RS29430 an N- adenosine oxo-C50:2-[acp] 5'-phosphate all-trans-heptaprenyl 1,4-dihydroxy- biosynthesis epoxyqueuosine alanine) pentapeptide diphosphate 4-(cytidine 5'-diphospho) daunorubicin IEK_RS06040 IEK_RS16375 riboflavin synthase: synthase: lipA kinase/ phosphoglucosamine 1,2-dione acylhydrolase polyprenyltransferase: acetoxyarylamine diphosphate 2-naphthoate protein: thiamine reductase: queG -2-C-methyl-D-erythritol sulfate RS02015 sulfate a [chaperone-ATP]- dihydrofolate IEK_RS07140 a tetrahydrofolate a [lipoyl-carrier phosphomethylpyrimidine lysine-- mutase: IEK_RS25785 (decyclizing): iolD scyllo-inosose IEK_RS03400 [co-chaperone]- IEK_RS09615 34 reductase: protein]-N 6 -[(R)- kinase: thiD tRNA ligase: a queuosine α-D-glucosamine DMKH2-13 a cyclodextrin RS07655 a cyclodextrin [scaffold protein- 1,4-dihydroxy- riboflavin 4-methyl-5-(2- 5-deoxy-D-glucuronate IEK_RS23510 dihydrolipoyl]-L-lysine thiaminase II: tenA IEK_RS14765 in tRNA 1-phosphate (2Fe-2S)] complex 2-naphthoate phosphooxyethyl) 4-aminobutanoate GabP 4-aminobutanoate bifunctional HMP-PP thiaminase II: tenA lysine- 5-deoxy- polyprenyltransferase: a tetrahydrofolate methionine thiazole a tRNA Lys bifunctional N- riboflavin kinase/ -tRNA glucuronate (R)-4'- all-trans- 3-[(3aS,4S,5R,7aS)-5- a long-linear DNA combined with 3-amino-4- a 3- a cis,cis- a (1->4)- phosphoenol SSQ1 IEK_RS11830 synthase: acetylglucosamine- S-methyl-L- 1,4-dihydroxy- NaMN 3'-GMP glutamate RS18355 glutamate FAD synthetase: ribF 4-amino-2-methyl-5- ligase: lysS isomerase: phosphopantothenoyl- L-homocysteine decaprenyl hydroxy-7a-methyl-1-oxo- α-D-glucan exogenous DNA to form hydroxybenzoate oxodocosanoyl- delta17,29-3- α-D-glucan pyruvate chaperone metH thiamine 5-(2-hydroxyethyl)-4-methylthiazole an L-lysyl- 1-phosphate methionine 2-naphthoate 1,4-dihydroxy- tRNA processing glycogen/starch/ 1,4-alpha- + + pyrimidinemethanol Lys L-cysteine diphosphate octahydro-1H-inden-4- a recombinational junction bifunctional arylamine N- bifunctional 2',3'- [acp] hydroxyC48:2- pyruvate ATPase: phosphate [tRNA ] uridyltransferase/ IEK_RS26445 bifunctional bifunctional homocysteine 1,4-dihydroxy- Holliday junction 3-oxoacyl-ACP H RS22015 H 2-naphthoate FMN yl]-3-oxopropanoyl-CoAacetyl-CoA C- alpha-glucan metallophosphatase/ acetyltransferase: [acp] 3-oxoacyl-ACP glucan kinase: pyk dihydrofolate synthase: bifunctional hydroxyethylthiazole lys glucosamine- 5-dehydro-2- phosphopantothenoylcysteine S-methyltransferase/ 2-naphthoate resolvase RecU: cyclic-nucleotide 2'- reductase: IEK_RS06040 polyprenyltransferase: acyltransferase: phosphorylase: IEK_RS13920 branching molybdenum cofactor biosynthesis reductase: hydroxymethylpyrimidine kinase: IEK_RS24670 a polycistronic deoxy-D-gluconate methylenetetrahydrofolate polyprenyltransferase: IEK_RS19260 5'-nucleotidase: phosphodiesterase/ IEK_RS10510 reductase: pyruvate a nucleotide RS06035 a nucleotide bifunctional IEK_RS23060 1-phosphate decarboxylase/ IEK_RS01120 IEK_RS03370 IEK_RS03400 kinase/ tRNA precursor Detoxification IEK_RS02805 arylamine N- 3'-nucleotidase: IEK_RS10510 protein GlgB: kinase: a [chaperone- riboflavin kinase/ IEK_RS16375 glycine 4-methyl-5(B- acetyltransferase: 5-dehydro-2- phosphopantothenate--cysteine reductase: IEK_RS06335 IEK_RS11830 3-[(3aS,4S,5R,7aS)- α-D- resolution of recombinational[+ 2 isozymes] a (3R)-3-[+ 4 isozymes] an [2Fe-2S] thiamine [+ 2 isozymes] a long-linear [+ 2 isozymes] acetyltransferase: IEK_RS07080 a cis,cis-[+ 4 isozymes] IEK_RS03350 IEK_RS11150 sulfite RS17930 sulfite ADP]-[disordered- dihydrofolate cleavage phosphomethylpyrimidine hydroxyethyl) glmU deoxygluconokinase: ligase CoaBC: IEK_RS08385 met 1,4-dihydroxy- 5-hydroxy-7a-methyl- glucopyranose junction formation hydroxydocosanoyl- cluster protein FAD synthetase: ribF phosphate acetyl-CoA α-D-glucan β-D- delta17,29-3- a GlgE-glycogen form scaffold demethylmenaquinol-7 GTP kinase: thiD -thiazole histidine-- α iolC reactive oxygen species degradation 4'-phosphopantetheine 1-phosphate IEK_RS10405 pyruvate reductase: system synthase: N-acetyl- -D- oxidized GTP and 2-naphthoate 1-oxo-octahydro-1H- of two intact strands ribosylnicotinate 3-acetylamino-4- guanosine [acp] Peptide RS17165 Peptide protein] complex ATP FAD oxo-C48:2-[acp] cys IEK_RS23510 protein IEK_RS24665 bifunctional monophosphate tRNA ligase: glucosamine 5-dehydro-2-deoxy-D- dGTP detoxification polyprenyltransferase: indene-4-carboxyl-CoA hydroxybenzoate demethylmenaquinone serine non-chaperonin H: gcvH hydroxymethylpyrimidine biosynthesis protein: IEK_RS05605 a tRNA precursor a tRNA precursor 1-phosphate gluconate 6-phosphate superoxide IEK_RS03400 predicted ABC methyltransferase: GTP 3',8- a 7,8-dihydrofolate a 5-methyltetrahydrofolate molecular cysteine molybdopterin- hydroxymethyltransferase: kinase/ IEK_RS09615 histidine-- with a 5' with a 5' (2-aminoethyl) transporter of (2-aminoethyl) IEK_RS19450 cyclase glycine thiamine his bifunctional N- DMKH2-10 a short a short chaperone desulfurase: synthase IEK_RS01260 extension and extension and a superoxide dGTP phosphonate (2-aminoethyl) phosphonate MoaA: moaA cleavage phosphomethylpyrimidine 4-methyl-5-(2- tRNA ligase: acetylglucosamine- GTP chain RS11270 chain ATPase: IEK_RS02790 adenylyltransferase: phosphate short 3' extension dismutase: phosphonate menaquinol-7 [+ 2 isozymes] system kinase: thiD phosphooxyethyl)thiazole IEK_RS11180 an L-histidyl- a long 3' trailer fatty acid fatty acid pyridoxal 5'-phosphate biosynthesis I 1-phosphate IEK_RS19670 IEK_RS06040 [+ 2 isozymes] IEK_RS10025 (8S)-3',8-cyclo-7,8- His ribonuclease thymidylate protein thiamine phosphate [tRNA ] uridyltransferase/ a (2R)-2-hydroxy a [release factor]- a dipetide with an N- a cis,cis-delta9,21- a cis,cis- an (11Z)-3- α an [Fe-S cluster a [disordered- an [L-cysteine a carboxy-adenylated dihydroguanosine HMP-P a tRNA His P protein DHAP 3-oxopropanoate [+ 3 isozymes] methylmalonate semialdehyde an N-formyl-L- a sulfurated an alkylated DNA an N-modified an arylamine -amylose D-erythrose synthase: T: gcvT synthase: glucosamine- 8-oxo-dGTP 8-oxo-GTP even numbered hydrogen cyanide L-glutamine terminal L-aspartate 3-hydroxyC40:2- delta15,27-3- oxo-icos-11- acetamide RS00615 acetamide biosynthesis form [Fe-S] cluster desulfurase]-S- [small subunit of 5'-triphosphate ribonuclease component: hydrogen methionylaminoacyl-tRNA [sulfur carrier] aminoacyl-[tRNA] 1,4-alpha- 2+ 2+ 4-phosphate IEK_RS16380 1-phosphate methylmalonate- straight chain DNA-3- peptide chain peptidase E: arylamine N- [acp] 3-oxoacyl-ACP hydroxyC46:2- enoyl-[acp]3-oxoacyl-ACP Zn RS15700 Zn sulfanyl-L-cysteine molybdopterin synthase] NAD de novo biosynthesis bifunctional IEK_RS23060 PH: IEK_RS00405 malonate peptide deformylase: rhodanese aminoacyl- chaperone]-ATP scaffold protein] cyclic pyranopterin acetyltransferase: peroxide 8-oxo-dGTP semialdehyde 2,3,4-saturated methyladenine release factor IEK_RS18460 acetyltransferase: [acp] 3-oxoacyl-ACP glucan I (from aspartate) hydroxymethylpyrimidine thiamine phosphate a tRNA precursor semialdehyde IEK_RS07845 acyl-CoA domain- tRNA reductase: reductase: monophosphate IEK_RS05215 diphosphatase: dehydrogenase (CoA fatty acid glycosylase: N(5)-glutamine IEK_RS10405 reductase: branching kinase/ synthase: with a short glmU dehydrogenase: peptide deformylase: synthetase: containing hydrolase: dipeptidase IEK_RS10510 IEK_RS04105 synthase catalase: IEK_RS18275 IEK_RS22430 protein GlgB: a (6S)-5- glycine-- UDP-N-acetyl- mmsA acylating): mmsA IEK_RS09740 protein: IEK_RS00150 methyltransferase: PepV: arylamine N- [+ 4 isozymes] IEK_RS10510 [+ 3 isozymes] MoaC: moaC 4-phospho- asp phosphomethylpyrimidine IEK_RS24665 gly a tRNA 3' extension IEK_RS21260 [+ 3 isozymes] 8-oxo-GMP IEK_RS08395 a (R)-2-hydroxy a DNA containing a cis,cis- a (3R,11Z)-3- IEK_RS03350 5,10- bifunctional formyltetrahydrofolate tRNA ligase: α-D-glucosamine [+ 2 isozymes] IEK_RS18040 an alkylated an N-modified an uncharged prmC IEK_RS04165 acetyltransferase: a cis,cis-[+ 4 isozymes] a thiocarboxylated D-erythronate kinase: thiD precursor with formate a L-methionylaminoacyl-tRNA [+ even4 isozymes] numbered an apurinic/ 5 delta9,21-3- hydroxy-icos- L-aspartate acetyl-CoA [+ 3 isozymes] + an unsulfurated nucleobase amino acid tRNA a [release factor]-N a proteinogenic delta15,27-3- amylopectin phosphopantothenate biosynthesis I [small subunit of cyclic pyranopterin methylenetetrahydrofolate methylenetetrahydrofolate 5-formyltetrahydrofolate thiamine phosphate IEK_RS03105 a 5' extension ribonuclease UDP-N-acetylglucosamine 8-oxo-dGMP H NADH hydrogencarbonate propanoyl-CoA apyrimidinic site IEK_RS13920 oxo-C40:2-[acp] 11-enoyl-[acp] oxidase: bifunctional Gly H O hydroxyl radical diphosphate AMP straight chain thiocyanate -methyl-L-glutamine asp an N- phosphate reductase: IEK_RS06335 dehydrogenase/ cyclo-ligase: a glycyl-[tRNA ] PH: 2 [sulfur carrier] amino acid oxo-C46:2-[acp] molybdopterin synthase] IEK_RS05465 hydroxymethylpyrimidine 1-carboxyvinyltransferase: 2,3,4-saturated acetylarylamine methenyltetrahydrofolate IEK_RS06280 a tRNA Gly ribonuclease: IEK_RS05215 IEK_RS01170 O 3-methyl-2-oxobutanoate 2-iminosuccinate kinase/ 2 fatty acyl CoA molybdopterin (3R)-3-hydroxy-2-oxo- cyclohydrolase: IEK_RS06795 a 5,10- a 5,10- phosphomethylpyrimidine IEK_RS00405 UDP-N-acetylglucosamine synthase: 4 phosphooxybutanoate quinolinate 3-methyl-2-oxobutanoate methylenetetrahydrofolate methenyltetrahydrofolate kinase: thiD 1-carboxyvinyltransferase: IEK_RS04085 thiamine autoinducer AI-2 degradation Degradation/Utilization/Assimilation - Other an N 6 -L- core a (1->4)- a (7Z,10Z,13Z,16Z a cis,cis-delta9,27- a cis,cis- a glucosylated a (1->4)- hydroxymethyltransferase: D-glyceraldehyde 3-phosphoserine/ bifunctional synthase NadA: murA a sulfurated M-antigen sn-glycero-3- NMN an L-aspartyl- pyruvate threonylcarbamoyladenine 37 a (3Z)-dec-3-enoyl-[acp] a malonyl-[acp] SAH α-D-glucan ,19Z)-3-oxodocosa- 3-hydroxyC46:2- delta13,25-3- glycogenin α-D-glucan panB 3-phosphate phosphohydroxythreonine IEK_RS05475 HMP-PP methionine-- α [sulfur carrier] oligosaccharide- phosphoethanolamine [tRNA Asn ] methylenetetrahydrofolate thiamine UDP-N-acetyl- - (variant) monomer glycogen/starch/ bifunctional [acp] hydroxyC44:2- 1,4-alpha- 1,4-alpha- transaminase: IEK_RS11480 tRNA ligase: AI-2 nylon-6 oligomer degradation in tRNA tRNA (N(6)-L- beta-ketoacyl- lipid A (E. coli glycerophosphoryl 7,10,13,16,19-pentaenoyl-[acp]3-oxoacyl-ACP Asp-tRNA(Asn) 3-oxoacyl-ACP molybdopterin 1-deoxy-D- dehydrogenase/ diphosphokinase: D-glucosamine- undecaprenyl 5-methylthioadenosine/S- alpha-glucan glucan glucan 2-dehydropantoate quinolinate an uncharged K-12 core type) diester reductase: metallophosphatase/ /Glu-tRNA(Gln) reductase: [acp] 3-oxoacyl-ACP 4-phosphooxy- methenyltetrahydrofolate IEK_RS00215 enolpyruvate autoinducer- threonylcarbamoyladenosine(37) [acyl-carrier- diphosphate adenosylhomocysteine phosphorylase: branching xylulose-5- IEK_RS08435 O-antigen(no GlcNAc) phosphodiesterase: IEK_RS10510 5'-nucleotidase: IEK_RS10510 reductase: branching molybdopterin L-threonine cyclohydrolase: IEK_RS06795 methionine-- tRNA 2 kinase: 6-aminohexanoate -C(2))- methylthiotransferase protein] amidotransferase 2-dehydropantoate 2- phosphate nicotinate- met UDP-N- nylon-6 polymer ligase domain- IEK_RS23805 deaminase: IEK_RS18085 IEK_RS03370 IEK_RS02805 IEK_RS10510 protein GlgB: protein GlgB: adenylyltransferase: IEK_RS12650 cyclic dimer MtaB: IEK_RS06060 6 synthase II: fabF α [+ 4 isozymes] subunit GatA: [+ 4 isozymes] reductase: IEK_RS18030 10 nucleotide thiamine diphosphate tRNA ligase: (4S)-4-hydroxy-5- a 2-methylsulfanyl-N -L- -D- a (3R,7Z,10Z,13Z,16Z a cis,cis- IEK_RS03350 synthase: an N - lipoate salvage II acetylenolpyruvoylglucosamine an unsulfurated a (5Z)-3-oxododec- containing [+ 4 isozymes] S-Inosyl-L- a (1->4)- [+ 2 isozymes] a cis,cis-[+ 4 isozymes] IEK_RS03350 IEK_RS04075 IEK_RS02545 phosphooxypentane- met 5'-deoxyadenosine threonylcarbamoyladenine 37 acyl-carrier protein glucopyranose ,19Z)-3-hydroxydocosa- 1-(β-D IEK_RS24995 delta9,27-3- 2-dehydropantoate 2- IEK_RS06815 formyltetrahydrofolate diphosphorylase an L-methionyl- reductase: IEK_RS02380 [sulfur carrier] 5-enoyl-[acp] protein: sn-glycerol homocysteine α-D-glucan an L-asparaginyl- delta13,25-3- a glycogen a glycogen molybdopterin Met 2,3-dione in tRNA ethanolamine 1-phosphate 7,10,13,16,19-pentaenoyl-[acp] ribofuranosyl) oxo-C46:2-[acp] reductase: IEK_RS08130 1-deoxy-D- 3-amino-1- (carboxylating) a [lipoyl-carrier [initiator tRNA ] UDP-N- di-trans,octa-cis IEK_RS01530 3-phosphate [tRNA Asn ] oxo-C44:2-[acp] adenine dinucleotide : IEK_RS05470 protein]-N 6 - initiator tRNA Met lipoprotein posttranslational -undecaprenyl E. coli M nicotinamide β-alanine xylulose 5- hydroxyacetone acetylenolpyruvoylglucosamine 6-aminohexanoate a nylon-6 LPS (R)-pantoate molybdopterin lipoyl-L-lysine modification diphosphate phosphate 1-phosphate NaMN reductase: IEK_RS08185 linear dimer linear oligomer molybdenumtransferase tetrapyrrole biosynthesis a [prolipoprotein]- UDP-N-acetyl- 3-hydroxy-5- pantoate--beta-alanine superpathway of heme b biosynthesis MoeA: IEK_RS16690 folate transformations I nicotinate-nucleotide II (from glycine) L-cysteine α-D-muramate phosphooxypentane- 6-aminohexanoate- 6-aminohexanoate- a reduced 6-methoxy-2-all- adenosine a Xaa-Pro a cis,cis-delta7,25- a cis,cis- a (1->4)- (R)-lipoate 6-caprolactam a [formate C ditrans,octacis- an unsulfurated an L-glutamyl- a [protein]- ligase: IEK_RS19310 from uroporphyrinogen-III [+ 2 isozymes] adenylyltransferase: 2,4-dione dimer hydrolase: dimer hydrolase: SAM a reduced flavodoxin an oleoyl-[acp] a malonyl-[acp] ferredoxin [iron- NADP + H + trans-octaprenyl- 2',3'-cyclic cys dipeptidyl- 3-hydroxyC44:2- delta11,23-3- α-D-glucan prolipoprotein undecaprenyldiphospho- [tRNA Gln ] L-tyrosine lipoate--protein 3-hydroxy-5- IEK_RS11295 acetyltransferase]-glycine [sulfur carrier] tyrosine 1,4-alpha- MoO -molybdopterin pyridoxine a tetrahydrofolate IEK_RS05950 gly diacylglyceryl IEK_RS11295 N-acetyl-(N- sulfur] cluster 1,4-benzoquinone monophosphate2',3'-cyclic-nucleotide cysteine peptidase Asp-tRNA(Asn) [acp] 3-oxoacyl-ACP hydroxyC42:2- 2 pyruvate beta-ketoacyl- ferredoxin- demethylmenaquinone uroporphyrinogen-III cofactor ligase A: phosphonooxypentane- [+ 2 isozymes] substrate [acp] 3-oxoacyl-ACP protein kinase: glucan (R)-pantothenate siroheme biosynthesis 5'-phosphate nicotinate adenine 5-aminolevulinate transferase: [+ 2 isozymes] formate-lyase [acyl-carrier- acetylglucosaminyl) -NADP(+) 2'-phosphodiesterase: desulfurase: Xaa-Pro /Glu-tRNA(Gln) reductase: IEK_RS21505 UDP-N-acetyl- 2,4-dione thiolase: methyltransferase: reductase: IEK_RS01455 branching dinucleotide synthase: hemA IEK_RS02065 1-activating protein] muramoyl-L-alanyl-γ- reductase: IEK_RS13815 IEK_RS05635 dipeptidyl- amidotransferase IEK_RS10510 uroporphyrinogen α-D-muramoyl- IEK_RS12640 IEK_RS19450 protein GlgB: pantothenate kinase: 5-aminolevulinate a [prolipoprotein]- D-isoglutaminyl-N-(β- 3-methyl-6-methoxy- [+ 2 isozymes] peptidase: subunit GatA: IEK_RS10510 [+ 2 isozymes] decarboxylase: formate-- NAD+ (lipoyl)adenylate Amine and Polyamine Biosynthesis γ 6-aminohexanoate enzyme: pflA a [formate C synthase II: fabF an IEK_RS03045oxidized [+ 2 isozymes] a cis,cis-[+ 4 isozymes] a [protein]- IEK_RS03350 IEK_RS28105 uroporphyrinogen-III S-1,2-diacyl-sn- L-alanyl- -D- a flavodoxin an (11Z)-3-oxo- D-asparaginyl)-L-lysyl- a sulfurated a dipeptideIEK_RS13225 with a cis,cis-[+ 4 isozymes] tetrahydrofolate synthetase, thiamine diphosphate DHAP met 5'-deoxyadenosine acetyltransferase]- acyl-carrier protein peptidoglycan NADPH ferredoxin [iron- 2-octaprenyl-1,4- 3'-AMP ala IEK_RS24995 delta7,25-3- L-tyrosine IEK_RS21590 uroporphyrinogen-III C- glycine porphobilinogen glutamyl-meso-2,6- semiquinone icos-11-enoyl-[acp] [sulfur carrier] a peptide a C-terminal an L-glutaminyl- delta11,23-3- type II pantothenate ligase: NH3- biosynthesis III lipoate--protein glyceryl-L-cysteine di-trans,octa-cisD-alanyl-D-alaninetransglycosylase: benzoquinone phosphate starch cleavage spermidine biosynthesis III diaminopimelate glycin -2-yl radical a peptidoglycan sulfur] cluster Gln oxo-C44:2-[acp] kinase: IEK_RS13030 methyltransferase: cobA PLP (Staphylococcus) ligase A: synthase: -undecaprenyl IEK_RS24040 L-proline [tRNA ] oxo-C42:2-[acp] coproporphyrinogen III system IEK_RS16805 dependent: 2-(2-carboxy-4- putrescine dimer (E. faeciums) uroporphyrinogen-III C- an N 10 - IEK_RS21505 IEK_RS05310 lipoprotein diphosphate (R)-4'-phosphopantothenate protein IEK_RS17310 HMP-PP methylthiazol-5- biosynthesis I methyltransferase: cobA formyltetrahydrofolate a [glycine- arg signal 6-oxohexanoate H: gcvH yl)ethyl phosphate porphobilinogen SAM precorrin-1 NAD + thiamine cleavage complex peptidase: 3-[(3aS,4S,7aS)-7a-methyl- guanosine a cis,cis-delta5,23- 38- 6 ditrans,octacis- salicyl-6-hydroxy-2- a uridine a [protein]- glycine phosphate H protein] N - arg IEK_RS08265 a 2'-deoxyribonucleoside a tripeptide a cytosine in DNA a RNA-DNA hybrid uroporphyrinogen-III C- hydroxymethylbilane arginine adenosylmethionine Carbohydrate Degradation a (3Z)-dodec-3-enoyl-[acp] a malonyl-[acp] 1,5-dioxo-octahydro-1H coenzyme A 2',3'-cyclic 3-hydroxyC42:2- repressor LexA cleavage synthase: undecaprenyldiphospho- cyclohexene-on-oyl 40 in tRNA L-histidine lipoyl-L-lysine synthase: decarboxylase, decarboxylase: arginine -inden-4-yl]propanoate deoxynucleoside monophosphate peptidase DNA (cytosine-5-)- ribonuclease [acp] RluA family histidine protoporphyrinogen IX protoporphyrinogen IX methyltransferase: cobA methionine an (S-diacyl- beta-ketoacyl- acyl-CoA synthetase: N-acetyl-(N- carboxylesterase: 2',3'-cyclic-nucleotide 3-oxoacyl-ACP system bifunctional IEK_RS23060 IEK_RS05300 biosynthetic: decarboxylase, a lipoprotein kinase: IEK_RS00305 methyltransferase: LexA kinase: uroporphyrinogen-III C- synthase: IEK_RS01830 ribose [acyl-carrier- IEK_RS17385 acetylglucosaminyl) IEK_RS02235 2'-phosphodiesterase: T: pepT H: rnhA reductase: pseudouridine protein thiamine biosynthetic: sn-glyceryl) signal peptide trehalose degradation fructose degradation adipate repressor: metH methylenetetrahydrofolate a (6S)-5- IEK_RS07920 adenosylmethionine phosphorylation chitobiose degradation muramoyl-L-alanyl- carboxylesterase: deoxynucleoside peptidase T: IEK_RS22150 ribonuclease IEK_RS10510 synthase: IEK_RS17760 methyltransferase: cobA T: gcvT preuroporphyrinogen -L-cysteinyl- protein] acyl-CoA synthetase: IEK_RS13815 IEK_RS09440 protoporphyrinogen dehydrogenase/ phosphate a [lipoyl-carrier IEK_RS07920 I (low osmolarity) γ DNA methylase: HII: IEK_RS20570 [+ 4 isozymes] bifunctional formyltetrahydrofolate decarboxylase: agmatine [apolipoprotein] synthase II: fabF 3-[(3aS,4S,7aS)-7a-methyl-IEK_RS09740 -D-isoglutaminyl- 6-hydroxy-2-IEK_RS09670 kinase: IEK_RS00310 [+ 2 isozymes] IEK_RS29895 a cis,cis-[+ 4 isozymes] a [protein]- oxidase: IEK_RS15530 methenyltetrahydrofolate synthase: protein]-N 6 - agmatine β N,N'- β-D-fructofuranose a 2'-deoxyribonucleoside cleaved precorrin-2 methylenetetrahydrofolate uroporphyrinogen- IEK_RS04795 -D-ribopyranose α,α-trehalose a (5Z)-3-oxo- N-(β-D-asparaginyl)peptidoglycan a proteinogenic IEK_RS29345 IEK_RS08550 [+ 4 isozymes] diacetylchitobiose acyl-carrier protein 1,5-dioxo-octahydro-1H- salicyl alcohol cyclohexen- 3'-GMP a dipeptide delta5,23-3- 38- N-phospho- protoporphyrinogen cyclohydrolase: IEK_RS06795 5-formyltetrahydrofolate IEK_RS24665 lipoyl-L-lysine D-ribose 1-phosphate 5'-monophosphate amino acid a 5-methylcytosine a nucleoside 5'- a pseudouridine repressor LexA heme b biosynthesis I (aerobic) precorrin-2 dehydrogenase/ thiamine III synthase: agmatinase: 6-phosphate 1-phosphofructokinase: tetradec-5-enoyl-[acp] inden-4-yl]propanoyl-CoA di-trans,octa-cis-L-lysyl-D-alanineatransglycosylase: peptidoglycan one-carboxylate DNA oxo-C42:2-[acp] L-histidine oxidase: IEK_RS21580 dAdoMet pyranase: 6'-phosphatechitin in DNA monophosphate 40 in tRNA lipoate biosynthesis methenyltetrahydrofolate cyclo-ligase: phosphate IEK_RS05305 speB a peptide pfkB -undecaprenyl dimerIEK_RS24040 (E. faecium dehydrogenase: an N-acyl-(S- IEK_RS23450 disaccharide β-D-fructose 1,6- and incorporation serine cyclohydrolase: IEK_RS06795 IEK_RS06280 alpha,alpha- diphosphate , tetrapeptide) uroporphyrinogen-III IEK_RS19860 uroporphyrinogen-III polyamine diacyl-sn-glyceryl) β-D-ribofuranose deacetylase: bisphosphate protoporphyrin IX III (Bacillus) putrescine phosphotrehalase: uroporphyrinogen hydroxymethyltransferase: bifunctional aminopropyltransferase: -L-cysteinyl- IEK_RS01865 sirohydrochlorin a 5,10- N-monoacetylchitobiose treC decarboxylase: IEK_RS01260 methylenetetrahydrofolate IEK_RS01000 a [2-oxoglutarate- a DNA containing adenine 1518 / 3-benzyl-3,6 - (1S,2R)-1- DNA with adenine:7,8- a cis,cis-delta7,19- an organic an oxidized ferrochelatase: hemH an octanoyl-[acp] [lipoprotein] 6'-phosphate a [protein]- F6P methenyltetrahydrofolate S methyl H O diphosphate 1519 dihydro-8- nitroaromatic IEK_RS21590 dehydrogenase/ thiamine dehydrogenase a sulfurated p L-homocysteine 2 bis(cysteinylglycine) C-(indol-3- 3-hydroxyC38:2- a protein sirohydrochlorin 1 SAM L-cysteine adenine in 16S rRNA ser hydroperoxide ferrochelatase: hemH S-methyl-5'- N -(3-aminopropyl) 6-phospho-beta- 6 coproporphyrinogen III methenyltetrahydrofolate thiamine diphosphate glucokinase: E2 protein] N - [sulfur carrier] phosphotriester fructose-6- manganese- ribosomal RNA - 6-(hydroxymethyl) yl)glycerol oxoguanine mismatch [acp] 3-oxoacyl-ACP thioredoxin- compound ferrochelatase: lipoyl methylated-DNA-- bifunctional homocysteine A/G-specific NAD(P)H a [glycine- cyclohydrolase: IEK_RS06795 biosynthesis I (E. coli) thiamine thioadenosine agmatine D-ribofuranose glucosidase: IEK_RS06290 octanoyl-L-lysine phosphate small subunit -diketopiperazinemembrane 3-phosphate tryptophan dependent thiol GPR protoheme IEK_RS19860 di-trans,poly-cis-undecaprenyl D-glucopyranose [protein]-cysteine S- S-methyltransferase/ dependent inorganic adenine reductase: thioredoxin a 5,10- diphosphokinase: 1 IEK_RS22030 D-glucopyranose synthase: aldolase: fsa dipeptidase: nitroreductase: endopeptidase: cleavage complex a 5-methyltetrahydrofolate phosphate biosynthesis N -aminopropylagmatine methyltransferase: pyrophosphatase: methyltransferase synthase glycosylase: IEK_RS10510 peroxidase: pathway methylenetetrahydrofolate 5-oxo-L-proline metabolism ribokinase: 6-phosphate lipA a [2-oxoglutarate methylenetetrahydrofolate 3-benzyl-3,6 - IEK_RS16285 siroheme H protein] N 6 - HMP-PP IEK_RS08435 ureohydrolase: speB [+ 2 isozymes] fructose-6- A: IEK_RS00200 IEK_RS08865 subunit IEK_RS24165 IEK_RS06005 rbsK an unsulfurated dehydrogenase IEK_RS09045a DNA without reductase: IEK_RS06335 IEK_RS13420 N 6 -dimethyladenine 1518 mutY [+ 4 isozymes] a reduced thiamine (2E,6E)-farnesyl N-acetyl-D- 5'-deoxyadenosine met a [protein]-S- bis(cysteinyl)- 6- a cis,cis- octanoyl-L-lysine thiamine a [protein] with a [protein] with 6 phosphate + 6 1519 gly beta: trpB [+ 2 isozymes] nitroaromatic an oxidized 5,10- IPP D-ribofuranose [sulfur carrier] E2 protein] N S methyl met phosphate H /N -dimethyladenine (hydroxymethyl) D-glyceraldehyde an apurinic site delta7,19-3- a peptide protoporphyrinogen IX guanylyl molybdenum phosphate diphosphate diphosphate spermidine an N-terminal an N-terminal glucosamine D-glucosamine methyl-L-cysteine p aldolase: fsa trp adenine thioredoxin methylenetetrahydrofolate di-trans,poly-cis-decaprenyl -lipoyl-L-lysine phosphotriester in 16S rRNA -diketopiperazine 3-phosphate within DNA oxo-C38:2-[acp] an alcohol compound synthase: L-glutamine L-glutamate 5-phosphate 6-phosphate D-glyceraldehyde reductase: IEK_RS06335 cofactor biosynthesis diphosphate:isopentenyl- dihydroxyacetone protoporphyrinogen bis(guanylyl molybdenum folate polyglutamylation IEK_RS23060 3-phosphate a [lipoyl-carrier MoO - diphosphate Amino Acid Degradation oxidase: IEK_RS15530 cofactor) biosynthesis lipoate biosynthesis 2 6 molybdopterin thiamine protoporphyrinogen MoO - and incorporation I protein] N - thioredoxin- undecaprenylcistransferase: 2 octanoyl-L-lysine disulfide a tetrahydrofolate cofactor molybdenum cofactor phosphate NAD phosphorylation di-trans,octa-cisIEK_RS08620 L-valine degradation I a [pyruvate an [RNA]-3'- a (7Z)-3-oxo- oxidase: IEK_RS21580 molybdopterin synthase: a [protein] with L-isoleucine degradation I L-ornithine degradation II (Stickland reaction) α-linolenate nicotinate PRPP a glycogen a nucleoside a ribonucleoside N,N'-diacetylchitobiose a 3-oxohexacosanoyl- a 3-oxoglutaryl- lipoyl reductase: guanylyltransferase: and dephosphorylation -undecaprenyl demethylmenaquinol- dehydrogenase a sulfurated formate ribonucleoside- hexadec-7- ethylphosphate a protein cofactor bis(molybdenum an octanoyl-[acp] IEK_RS24665 an N-terminal 5- SAM triphosphate triphosphate [acp] [acp] methyl ester protoporphyrin IX synthase: trxB IEK_RS03885 diphosphate E2 protein] N 6 - [sulfur carrier] acyl-CoA synthetase: nicotinate glycogen/starch/ chitin 2',3'- enoyl-[acp] cofactor) serine bifunctional formate--tetrahydrofolate thiamine 9 biosynthesis nucleoside triphosphate anaerobic 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP alkaline + oxo-L-proline val lipoyl alpha-glucan disaccharide lipA molybdopterin- phosphate NAD undecaprenyl- γ-L-glutamyl ile octanoyl-L-lysine IEK_RS17385 phosphoribosyltransferase: ribonucleoside- cyclophosphate reductase: reductase: reductase: phosphatase: ferrochelatase: hemH synthase: a [lipoyl-carrier hydroxymethyltransferase: folylpolyglutamate ligase: IEK_RS16805 all-trans- glutathione L-ornithine synthase: pyrophosphohydrolase: RNA 2',3'-cyclic endopeptidase a [lipoyl-carrier guanine diphosphate 1,4-dihydroxy- 5-phosphate [+ 4 isozymes] IEK_RS23775 phosphorylase: deacetylase: IEK_RS03885 6 IEK_RS01260 synthase/dihydrofolate nonaprenyl pyroglutamyl- branched-chain- a [pyruvate triphosphate phosphodiesterase: IEK_RS10510 IEK_RS10510 IEK_RS04105 IEK_RS12540 La: lon ferrochelatase: hemH 6 protein]-N -[(R) lipA IEK_RS00125 bis(molybdenum protein] N - a reduced dinucleotide phosphatase: 2-naphthoate branched-chain- nicotinate IEK_RS03370 IEK_RS01865 synthase: IEK_RS05335 10 diphosphate 1,4-dihydroxy- peptidase amino-acid an unsulfurated α-D- reductase: nrdD N-acetyl-β-D- IEK_RS04170 [+ 4 isozymes] [+ 4 isozymes] [+ 3 isozymes] [+ 3 isozymes] cofactor) -dihydrolipoyl]- an N -formyltetrahydrofolate amino-acid 5'-deoxyadenosine met dehydrogenase AMP diphosphate α-linolenoyl-CoA a nucleoside 5'- an [RNA]-3'- a (3R)-3- a (3R)-3- a (3R,7Z)-3- octanoyl-L-lysine thioredoxin biosynthesis IEK_RS20085 6 phosphoribosyltransferase: a 2'-deoxyribonucleoside protoheme L-lysine acid NAD kinase: 2-naphthoate I: pcp transaminase: ornithine [sulfur carrier] E2 protein] N glucopyranose an α-limit dextrin acetate glucosaminyl-(1->4) hydroxyhexacosanoyl- hydroxyglutaryl- hydroxy-hexadec- ethanol a peptide molybdenum cofactor lipoyl a 5,10-methylenetetrahydrofolate guanylyl transaminase: monophosphate 5'-triphosphate ribunucleoside- bifunctional protein B: mobB thiamine phosphatase: IEK_RS21030 [+ 3 isozymes] polyprenyltransferase: IEK_RS18160 aminotransferase: -lipoyl-L-lysine IEK_RS04250 1-phosphate -D-glucosamine [acp] [acp] methyl ester 7-enoyl-[acp] guanylyltransferase: synthase: a tetrahydrofolate molybdenum IEK_RS18160 2'-phosphate bifunctional folylpolyglutamate diphosphate IEK_RS22670 NAD kinase: di-trans,octa-cis- IEK_RS11830 IEK_RS21285 NaMN IEK_RS03885 lipA cofactor 5-oxo-L-proline branched-chain- branched-chain- folylpolyglutamate synthase/dihydrofolate [+ 3 isozymes] IEK_RS04495 undecaprenyl phosphate D-ornithine bis(guanylyl a [lipoyl-carrier 1,4-dihydroxy- amino-acid amino-acid 6 synthase/dihydrofolate synthase: IEK_RS05335 L-glutamate-5- molybdopterin) protein]-N -[(R) demethylmenaquinol- lipoate salvage I 2-naphthoate 5-oxoprolinase: transaminase: transaminase: 2503 a 2-methyl 1402 acyl carrier cofactor -dihydrolipoyl]- 6 biosynthesis I synthase: IEK_RS05335 polyprenyltransferase: IEK_RS20020 semialdehyde adenine a linear malto- 7-carboxy-4-methyl-3,5- salicin 6- a cytidine a 3,5,7,9,11,13,15- a (3R,5Z)-3- a SpoIVB an N 10 -formyltetrahydrofolate IEK_RS12125 IEK_RS20020 (S)-3-methyl-2- pristanate a 3-oxotetracosanoyl- a 3-oxoicosanoyl- a phosphate + branched 2,3,4- oligosaccharide in 16S rRNA hepta-oxo- hydroxy-tetradec- peptidase protein activation L-lysine all-trans- NADP IEK_RS03400 oxopentanoate in 23S rRNA dioxoheptanoyl-CoA phosphate [acp] [acp] monoester 1,4-dihydroxy- (R)-lipoate a 5,10-methylenetetrahydrofolate base-degraded 3-methyl-2- 23S rRNA acyl-CoA synthetase: saturated fattyacyl-CoA acid glycogen/starch/ acetyl-CoA C- 6-phospho-beta- 16S rRNA hexadecanoyl-[PKS-acp]aldo/keto 3-oxoacyl-ACP 3-oxoacyl-ACP 5-enoyl-[acp]3-oxoacyl-ACP alkaline Precursor hexaprenyl demethylmenaquinol-9 glu (2R,4S)-2, 4- an apo acyl- 2-naphthoate lipoate--protein thiamine salvage demethylmenaquinol-8 biosynthesis I oxobutanoate 3-methyl-2- (adenine(2503)-C(2) IEK_RS09740 alpha-glucan acyltransferase: glucosidase: (cytidine(1402)-2'-O) SpoIVB diphosphate 1,4-dihydroxy- diaminopentanoate synthetase: reductase: reductase: reductase: reductase: phosphatase: ligase A: oxopentanoate )-methyltransferase [+ 4 isozymes] phosphorylase: IEK_RS01120 IEK_RS22030 -methyltransferase: peptidase: carrier protein4'-phosphopantetheinyl formylaminopyrimidine 3-methyl-2- (S)-1-pyrroline- IEK_RS09740 IEK_RS14730 IEK_RS10510 IEK_RS10510 IEK_RS04105 IEK_RS03330 glutathionylspermidine 2-naphthoate IEK_RS21505 dehydrogenase: RlmN: IEK_RS08410 IEK_RS03370 spoIVB 1,4-dihydroxy-2-naphthoate oxobutanoate 5-carboxylate α [+ 2 isozymes] [+ 2 isozymes] rsmI [+ 6 isozymes] [+ 4 isozymes] [+ 4 isozymes] [+ 3 isozymes] transferase: polyprenyltransferase: formylaminopyrimidine 2503 [+ 4 isozymes]a 2-methyl -D- a 2'-O- 9-hydroxy-3,5,7,11,13,15- a (3R)-3- a (3R)-3- a (5Z)-3-oxo- [+ 2 isozymes] biosynthesis (lipoyl)adenylate 1,4-dihydroxy-2-naphthoate Fatty Acid and Lipid Biosynthesis dehydrogenase: lpdA a 2-methyladenine AMP diphosphate pristanoyl-CoA a linear malto- 5-carboxy-2-methyl- β-D-glucose a SpoIVB IEK_RS15795 IEK_RS11830 deformylase: pyrroline-5- 5'-deoxyadenosine met branched glucopyranose acetyl-CoA salicyl alcohol methylcytidine 1402 hexaoxohexadecanoyl- hydroxytetracosanoyl- hydroxyicosanoyl- tetradec-5- an alcohol menaquinol-9 biosynthesis menaquinol-8 biosynthesis polyprenyltransferase: lpdA in 23S rRNA AMP diphosphate oligosaccharide 3-oxopentanoyl-CoA 6-phosphate peptidase IEK_RS24365 6 37 2-methylbutanoyl-CoA carboxylate 1-phosphate in 16S rRNA holo-ACP glutathione spermidine 1,4-dihydroxy- lipoate--protein N -L-threonylcarbamoyladenosine (2R)-2-amino-4- 2,3,4-saturated [PKS-acp] [acp] [acp] enoyl-[acp] aminomethylpyrimidine IEK_RS11830 palmitate biosynthesis II (bacteria and plants) reductase: synthase: glutathionylspermidine 2-naphthoate ligase A: -modified tRNA biosynthesis isobutanoyl-CoA oxopentanoate fatty acyl-CoA demethylmenaquinol-9 demethylmenaquinol-8 1,4-dihydroxy-2-naphthoate palmitoleate stearate phosphatidylethanolamine S-2-methylbutryl- IEK_RS25640 IEK_RS25435 synthase: IEK_RS19120 polyprenyltransferase: IEK_RS21505 thiaminase II: tenA a holo acyl- a [lipoyl-carrier demethylmenaquinone demethylmenaquinone polyprenyltransferase: biosynthesis I (from biosynthesis II biosynthesis I CoA:FAD glutathionylspermidine IEK_RS03400 thiaminase II: tenA thr [+ 2 isozymes] 6 an acetoacetyl-[acp] (5Z)-dodec-5-enoate) (bacteria and plants) oxidoreductase: a 3-methyl- a pseudouridine 1915 9-carboxy-6-methyl-3,7- arbutin-6- an adenine 22 a (9Z)-3-oxo- carrier protein demethylmenaquinol-6 protein]-N - methyltransferase: methyltransferase: IEK_RS03400 a 2-oxo carboxylate phytenate a D-tryptophanyl- a 3-oxopimeloyl- a dipeptide a nucleoside synthase: IEK_RS12900 demethylmenaquinol-8 a CDP-diacylglycerol threonylcarbamoyl- branched 2,3,4- a malonyl-[acp] octadec-9- lipoyl-L-lysine IEK_RS19450 IEK_RS19450 4-amino-2-methyl-5- a (5Z)-dodec- IEK_RS01130 in 23S rRNA dioxononanoyl-CoA phosphate in tRNA [tRNA Trp ] diphosphate glutathionylspermidine 3-oxoacyl-ACP a palmitoyl-[acp] AMP synthase: pro 2-oxoacid ferredoxin acyl-CoA synthetase: saturated fatty acid acetyl-CoA C- 6-phospho-beta- [acp] methyl ester menaquinol-9 menaquinol-8 pyrimidinemethanol 5-enoyl-[acp] CDP-diacylglycerol--serine (E)-2- acetyl-CoA acyl-CoA 23S rRNA tRNA (adenine(22) D-aminoacyl- malonyl-[acyl- 3-oxoacyl-ACP enoyl-[acp]3-oxoacyl-ACP membrane nucleoside- beta-ketoacyl- 3-oxo- IEK_RS01215 methylacrylyl-CoA reductase: O-phosphatidyltransferase: (L-threonylcarbamoyl) oxidoreductase IEK_RS17385 synthetase: (pseudouridine(1915)- acyltransferase: glucosidase: -N(1))- tRNA carrier protein] O- reductase: reductase: dipeptidase: diphosphate [acyl-carrier- stearoyl-[acp] methylcrotonoyl-CoA proline IEK_RS10510 pssA adenylate subunit beta: [+ 4 isozymes] IEK_RS09740 N(3))-methyltransferase IEK_RS01120 IEK_RS22030 methyltransferase deacylase: methyltransferase IEK_RS10510 IEK_RS04105 IEK_RS08865 kinase: protein] synthase: fabF tiglyl-CoA racemase: IEK_RS08875 [+ 4 isozymes] a 3-oxooctadecanoyl- 6 3 RlmH: IEK_RS00565 [+ 2 isozymes] [+ 2 isozymes] 1 TrmK: IEK_RS06155 IEK_RS19440 CDP-diacylglycerol--serine N -L- hydrase: IEK_RS22330 [+ 4 isozymes]a 3-methyl- an N - N - IEK_RS05585 BioC: bioC a (3R)-3-[+ 4 isozymes] a (3R,9Z)-3-[+ 3 isozymes] a proteinogenic synthase a reduced ferredoxin diphosphate AMP phytenoyl-CoA 7-carboxy-4-methyl- β-D-glucose a malonyl-[acp] a nucleoside a (3R)-3- [acp] O-phosphatidyltransferase: threonylcarbamoyladenine IEK_RS02680 H + CO an acyl-CoA methylpseudouridine 1915 acetyl-CoA hydroquinone methyladenine 22 a tRNA Trp D-tryptophan hydroxypimeloyl- hydroxy-octadec- amino acid peptidoglycan biosynthesis I Cell Structure Biosynthesis II: fabF (S)-3-hydroxy- proline L-threonine [iron-sulfur] cluster 2 branched 5-oxoheptanoyl-CoA 6-phosphate triphosphate a (7Z)-3-oxotetradec- pssA synthase: tsaD diphosphate AMP in 23S rRNA in tRNA methyl ester (meso-diaminopimelate containing) hydroxybutanoyl-[acp] 3-oxoacyl-ACP a 3-sn-phosphatidyl- isobutanoyl-CoA (2S,3S)-3-hydroxy-2- racemase: degradation I 2,3,4-saturated [acp] methyl ester 9-enoyl-[acp] 7-enoyl-[acp] an N 6 -L- reductase: L-serine methylbutanoyl-CoA IEK_RS13370 fatty acyl-CoA UDP-N-acetyl- threonylcarbamoyladenine 37 3-oxoacyl-ACP IEK_RS10510 phosphatidylserine α-D-glucosamine in tRNA thr reductase: [+ 4 isozymes] decarboxylase: D-proline UDP-N-acetylglucosamine threonine ditrans,octacis- 3-oxo-(7Z)- 3-oxo-(7Z)- (5E)-3-oxo- a guanine 966 a negatively a (7Z)-3- IEK_RS04105 a (3R)-3- IEK_RS05920 (S)-3-hydroxy- seleno-L- linoleate glycerophosphoglycerol a D-aspartyl- histidinol pyrazinamide 1-carboxyvinyltransferase: dehydratase: undecaprenyldiphospho- hexadecenoyl-CoA tetradecenoyl-CoA dodec-5- in 16S rRNA asp supercoiled DNA oxohexacos- a (2E)-but-2-enoyl-[acp] [+ 3 isozymes] hydroxyoctadecanoyl- isobutanoate homocysteine [tRNA ] IEK_RS01170 peptidoglycan maturation (meso-diaminopimelate containing) an L-1- 2-methylacetoacetyl-CoA IEK_RS18135 acyl-CoA synthetase: N-acetyl-(N- glycerophosphodiester acetyl-CoA C- acetyl-CoA C- enoyl-CoA 16S rRNA DNA 7-enoyl-[acp]3-oxoacyl-ACP histidinol amidase: a (3R,7Z)-3- [acp] 3-hydroxyisobutyrate 5-methyltetrahydropteroyltriglutamate- acetyl-CoA C- D-aminoacyl- crotonyl-[acyl- phosphatidylethanolamine IEK_RS09740 acetylglucosaminyl) phosphodiesterase: acyltransferase: acyltransferase: (guanine(966)-N(2) topoisomerase reductase: IEK_RS17015 UDP-N-acetylglucosamine lipid II (meso hydroxytetradec- dehydrogenase: acetyl-CoA C- threonine acyltransferase: tRNA dehydrogenase: - homocysteine S- [+ 4 isozymes] γ IEK_RS14120 IEK_RS09745 IEK_RS09745 )-methyltransferase III: IEK_RS17740 amidase: 1-carboxyvinyltransferase: carrier-protein] 7-enoyl-[acp] 5-aminopentanoate ammonia-lyase: muramoyl-L-alanyl- -D- IEK_RS01120 deacylase: IEK_RS10510 hisD diaminopimelate containing) IEK_RS15895 acyltransferase: methyltransferase: IEK_RS07695 [+ 2 isozymes] [+ 2 isozymes] RsmD: rsmD [+ 3 isozymes] IEK_RS17660 murA reductase: IEK_RS24660 isoglutaminyl-L-lysyl-peptidoglycan [+ 4 isozymes] an N 2 - IEK_RS05585 [+ 4 isozymes] peptidoglycan (S)-methylmalonate- IEK_RS01120 (2Z)-2-aminobut- AMP diphosphate linoleoyl-CoA sn-glycerol (5Z)- (5Z)- [+ 2 isozymes] a (3R,7Z)-3- pyrazine-2- α IEK_RS20945 (glycyl) -D-alanyl-D-alanine acetyl-CoA acetyl-CoA (3E)-dec-3- 966 asp a relaxed DNA his UDP-N-acetyl- - a (2E)-octadec- SeMet 5 transglycosylase: glycerol methylguanine tRNA D-aspartate hydroxyhexacos- transglycosylase: semialdehyde [+ 2 isozymes] 2-enoate a peptidoglycan di-trans,octa-cis 3-phosphate tetradecenoyl-CoA dodecenoyl-CoA acetyl-CoA carboxylate D-glucosamine- 2-enoyl-[acp] IEK_RS24040 enoyl-CoA in 16S rRNA 7-enoyl-[acp] IEK_RS24040 α-diglucosyldiacylglycerol dimer (S. aureus) -undecaprenyl enolpyruvate a butanoyl-[acp] a (2E,7Z)-tetradeca- propanoyl-CoA acetyl-CoA a nascent peptidoglycan steroyl-[acp] biosynthesis methylmalonate- diphosphate 2,7-dienoyl-[acp] UDP-N- with (L-alanyl-γ-D- 3-oxoacyl-[acyl- reductase: semialdehyde L-serine acetylenolpyruvoylglucosamine cis-∆ 7 - IEK_RS20945 a 1,2-diacyl-sn-glycerol dehydrogenase degradation an N 6 -L- glutamyl-meso-2,6- carrier-protein] 2-iminobutanoate a long-chain 3-(4-hydroxyphenyl)- 3-oxo-(9Z)- 3-oxo-(11Z)- a cytidine 1402 (11Z,14Z,17Z)-3- D-firefly a (5Z)-3- a [protein]- an organic reductase: IEK_RS02380 (S)-3-amino-2- 37 decanoate H O diaminopimeloyl-D-alanyl- reductase: tetradecenoyl- (CoA acylating) threonylcarbamoyladenine 2,3,4-saturated 2 oxotetracos- a stearoyl-[acp] methylpropanoate 3-oxo-propanoyl-CoA octadecenoyl-CoA octadecenoyl-CoA ATP H O in 16S rRNA oxoicosatrienoyl-CoA luciferyl-CoA L-arginine molecule UDP-N- D-alanine) pentapeptide IEK_RS08480 [acp]:NAD+ α : mmsA ser in tRNA acyl-CoA synthetase: fatty acidacyl-CoA acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- 2 ribosomal RNA 3-oxoacyl-[acyl- acyl-CoA 5-enoyl-[acp]3-oxoacyl-ACP cytochrome a 1,2-diacyl-3-O-( -D- tRNA ATPase: protein acetylenolpyruvoylglucosamine oxidoreductase: [+ 2 isozymes] L-serine IEK_RS09740 synthetase: acyltransferase: acyltransferase: acyltransferase: small subunit carrier-protein] thioesterase: reductase: P450: beta-ketoacyl- glucopyranosyl)-sn-glycerol threonylcarbamoyladenosine IEK_RS15345 arginine kinase: reductase: IEK_RS08185 IEK_RS20945 ammonia- [+ 4 isozymes] IEK_RS09740 IEK_RS01120 IEK_RS09745 IEK_RS09745 methyltransferase reductase: IEK_RS17105 IEK_RS10510 IEK_RS14300 glu [acyl-carrier- diglucosyl 2-oxobutanoate dehydratase: IEK_RS05615 [+ 8 isozymes] IEK_RS26220 ala UDP-N-acetyl- 6 [+ 2 isozymes] 4 H: mraW IEK_RS08480 a [protein]- [+ 3 isozymes] protein] a (7Z)-tetradec- diacylglycerol lyase, a cyclic N -L- [+ 4 isozymes] [+ 2 isozymes] [+ 2 isozymes] an N - (3R,11Z,14Z,17Z)-3- [+ 3 isozymes] a (3R,5Z)-3-[+ 4 isozymes] α-D-muramate a nascent peptidoglycan a nascent peptidoglycan a mature peptidoglycan with hydrogencarbonate diphosphate AMP decanoyl-CoA (7Z)- H + phosphate ADP ω iron-sulfur- a long-chain acetyl-CoA 4-hydroxybenzoyl-CoA acetyl-CoA palmitoleoyl-CoA acetyl-CoA 1402 D-firefly luciferin N -phospho- an alcohol glutamate synthase 7-enoyl-[acp] stearate synthase: 2-ketobutyrate threonylcarbamoyladenosine hexadecenoyl-CoA methylcytidine hydroxyicosatrienoyl- hydroxytetracos- with (L-alanyl-γ-D-glutamyl- with D,D cross-links (meso- (L-alanyl-γ-D-glutamyl-meso- L-tryptophan degradation to AMP diphosphate 2,3,4-saturated L-arginine racemase: II: fabF IEK_RS24285 dependent, formate- 37 in tRNA in 16S rRNA CoA 5-enoyl-[acp] UDP-N- meso-2,6-diaminopimeloyl- diaminopimelate containing) 2,6-diaminopimeloyl-D-alanyl- 3-oxoacyl-[acyl- fatty acyl CoA acyl-CoA a 1,2-diacyl-3-O-(α-D- 2-amino-3-carboxymuconate subunit lyase: pflB acetylmuramate-- IEK_RS22505 D-alanine) tetrapeptide D-alanine) pentapeptide Secondary Metabolite Biosynthesis carrier-protein] a 3-oxohexanoyl-[acp] synthetase: glucopyranosyl(1->2)-O-α-D- semialdehyde beta: sdaAB L-alanine ligase: glutamate reductase: propanoyl-CoA IEK_RS09740 glucopyranosyl)-sn-glycerol L-arginine IEK_RS04255 racemase: L,D- LD- L,D- petrobactin biosynthesis IEK_RS08480 trp L-serine α,ω-9Z- (5Z,8Z,11Z,14Z,17Z) an all-trans 5-cis, 7-trans-3-oxo- a double-stranded adenine 37 a (6Z)-3- a mature peptidoglycan preQ biosynthesis 3-oxoacyl-ACP degradation VI 16-hydroxypalmitate octanoate 3'-UMP an acyl-CoA H O a DNA segment acetamide 0 [+ 4 isozymes] ammonia- val 2 oxooctadec- IEK_RS05205 transpeptidase: carboxypeptidase: transpeptidase: autoinducer AI-2 biosynthesis I beta-ketoacyl- tryptophan 2,3- octadecenedioate -icosapentaenoyl-CoA -retinyl ester tetradecadienoyl-CoA oligonucleotide in tRNA with D,D cross-links (meso- reductase: (arginase 2 pathway) bifunctional 1 bifunctional 2',3'- UDP-N-acetyl- IEK_RS22945 IEK_RS17545 a mature peptidoglycan [acyl-carrier- dioxygenase: lyase, acyl-CoA synthetase: acyl-CoA synthetase: acyl-CoA acyl-CoA carboxylesterase: acetyl-CoA C- tRNA1(Val) acyl-CoA 6-enoyl-[acp]3-oxoacyl-ACP recombinase: amidase: IEK_RS22945 diaminopimelate containing) 3-dehydroshikimate IEK_RS10510 stearoyl-CoA α-D-muramoyl- D-glt γ iron-sulfur- IEK_RS09740 IEK_RS09740 synthetase: thioesterase: IEK_RS02235 acyltransferase: oligoribonuclease/ (adenine(37)-N6)- cyclic-nucleotide 2'- thioesterase: IEK_RS17660 [+ 2 isozymes] [+ 2 isozymes] [+ 2 isozymes] with (L-alanyl- -D-glutamyl- protein] arg N-Formyl-L-kynA reductase: IEK_RS29065 L-alanine dehydroshikimate an apo-[aryl- GTP [+ 4 isozymes] dependent, propanoyl [+ 4 isozymes] [+ 4 isozymes] IEK_RS17385 IEK_RS17105 carboxylesterase: IEK_RS01120 PAP phosphatase methyltransferase: phosphodiesterase/ IEK_RS17105 amidase: meso-2,6-diaminopimeloyl- SAM synthase arginase: rocF kynurenine IEK_RS10510 [+ 2 isozymes] a nascent peptidoglycan a nascent peptidoglycan a nascent peptidoglycan carrier protein] GTP cyclohydrolase sphingomyelin metabolism subunit phosphate [+ 4 isozymes] [+ 3 isozymes] IEK_RS09670 [+ 2 isozymes] NrnA: IEK_RS04670 IEK_RS00235 3'-nucleotidase: [+ 3 isozymes] a DNA segment IEK_RS17015 D-alanine) tetrapeptide dehydratase: a (3R)-3- II: fabF an N 6 - a (3R,6Z)-3-[+ 4 isozymes] UDP-N- with L,D cross links (meso- with (L-alanyl-γ-D- with (L-alanyl-γ-D-glutamyl- I FolE: folE arginase: rocF arylformamidase: beta: sdaAB AMP diphosphate 16-hydroxypalmitoyl-CoA diphosphate AMP octanoyl-CoA ω-carboxy- (5Z,8Z,11Z,14Z,17Z) (3Z,5E)-dodeca- a nucleoside 5'- IEK_RS07080 in reverse IEK_RS17370 holo-ACP hydroxyhexanoyl-[acp] 2-aminoprop- acetate kinase: coenzyme A a fatty acid all-trans-retinol acetyl-CoA methyladenine 37 a carboxylate hydroxyoctadec- acetate acetylmuramoyl- diaminopimelate containing) glutamyl-meso-2,6- meso-2,6-diaminopimeloyl- a (9Z)-3-oxohexadec- an N-acyl- L-ornithine kynB AMP diphosphate (9Z)-octadec- -icosapentaenoate 3,5-dienoyl-CoA monophosphate uridine orientation synthase: GTP cyclohydrolase 2-enoate IEK_RS04520 in tRNA val 6-enoyl-[acp] SAH 9-enoyl-[acp] 9-enoyl-CoA 1 L-alanine--D- diaminopimelate) tripeptide glycine) tetrapeptide protocatechuate IEK_RS25435 I FolE: folE sphingosylphosphorylcholine glutamate ligase: 7,8-dihydroneopterin 3'-triphosphate 3-oxoacyl-ACP ornithine L-kynurenine acyl-CoA 4'-phosphopantetheinyl 5'-methylthioadenosine/ propanoate IEK_RS08170 reductase: sphingomyelin aminotransferase: a mature peptidoglycan synthetase: transferase: S-adenosylhomocysteine 527 an (11Z)-3- 6-carboxytetrahydropterin a (2E)-hex-2-enoyl-[acp] IEK_RS10510 phosphodiesterase: IEK_RS21285 a [protein]- a guanine 3'-cmp a nucleoside with L,D cross-links (meso- a mature peptidoglycan a mature peptidoglycan IEK_RS17385 IEK_RS15795 18-hydroxystearate a [protein]-L-lysine uroporphyrinogen-III canavaninosuccinate a carboxylic ester 3'-dephospho- 4-guanidinobutyramide oxooctadec- acrylamide UDP-N-acetyl- synthase QueD: queD nucleosidase: mtnN sph 2-iminopropanoate dGTP L-glutamine ATP in 16S rRNA triphosphate meso- α diaminopimelate containing) with (L-alanyl-γ-D- with (L-alanyl-γ-D-glutamyl- (3,4- [+ 4 isozymes] L-glutamate-5- acyl-CoA synthetase: uroporphyrinogen-III C- argininosuccinate carboxylesterase: CoA bifunctional 2',3'- amidase: amidase: -D-muramoyl-L- a holo-[aryl- 6-carboxytetrahydropterin [+ 3 isozymes] hexanoyl-[acyl- sphingosylphosphorylcholine protein-glutamine ribosomal RNA 11-enoyl-[acp]3-oxoacyl-ACP diaminopimelate meso-2,6-diaminopimeloyl- a (3R,9Z)-3- semialdehyde dGTP dephospho- cyclic-nucleotide 2'- nucleoside alanyl-D-glutamate glutamyl-meso-2,6- dihydroxybenzoate) synthase QueD: queD a sphingosine 3-hydroxy- L-histidine degradation I IEK_RS09740 gamma- methyltransferase: cobA lyase: argH IEK_RS02235 small subunit IEK_RS17015 reductase: IEK_RS17015 carrier protein] carrier-protein] hydroxyhexadec- triphosphohydrolase: CoA kinase: triphosphatase diaminopimelate) tripeptide glycine) tetrapeptide adenylate S-ribosyl-L-homocysteine [+ 4 isozymes] glutamyltransferase: uroporphyrinogen-III C- argininosuccinate carboxylesterase: methyltransferase phosphodiesterase/ amidase: IEK_RS10510 amidase: reductase: 9-enoyl-[acp] ceramide L-kynurenine IEK_RS04785 YtkD: ytkD UDP-N- 6-carboxy-5,6,7,8-tetrahydropterin IEK_RS01715 IEK_RS07915 methyltransferase: cobA lyase: IEK_RS10115 IEK_RS09670 G: IEK_RS00430 3'-nucleotidase: IEK_RS17660 IEK_RS17660 spermidine citrate IEK_RS20945 a protein with an an N 7 - [+ 4 isozymes] acyl-CoA pyruvate AMP diphosphate 18-hydroxystearoyl-CoA 2'-deoxyguanosine triphosphate ADP coenzyme A H + IEK_RS07080 a (3R,11Z)-3- a nucleoside acetylmuramoyl- S-ribosylhomocysteine kynureninase: his 6 precorrin-2 fumarate L-canavanine a carboxylate an alcohol 527 4-guanidinobutanoate acrylate synthetase: 7-carboxy-7-deazaguanine (S)-1-pyrroline- N -(γ-glutamyl)- methylguanine hydroxyoctadec- diphosphate L-alanyl-D- spermidine- lyase: IEK_RS03735 a hexanoyl-[acp] long-chain fatty kynU histidine cytidine D-ala IEK_RS17385 synthase QueE: queE 5-carboxylate L-lysine crosslink in 16S rRNA 11-enoyl-[acp] glutamate--2, 6- citrate ligase: a (2E,9Z)-hexadeca- acid activation ammonia- 7-carboxy-7-deazaguanine pyrroline-5- 3-hydroxyanthranilate lyase: hutH diaminopimelate D-alanine--D- a 3,4- IEK_RS17395 AI-2 3-oxoacyl-[acyl- 2,9-dienoyl-[acp] a long-chain synthase QueE: queE carboxylate urocanate an oxidized a 5'-half-tRNA 1498 ligase: alanine ligase: dihydroxybenzoyl- carrier-protein] fatty acid an (S)-2- 3-oxo-(9Z)- a 3'-half-tRNA a uracil (5Z)- a cis-delta21-3- N-citryl-spermidine palmitoleoyl- acyl-CoA reductase: (2E)-hexadecenoate 2-methylbutanoate ammonium H O ferredoxin [iron- molecule with butanoyl-CoA acetyl-CoA [DNA] carbonic acid arsenate IEK_RS08160 reductase: 2 halocarboxylate hexadecenoyl-CoA in 16S rRNA dodecenoyl-CoA IEK_RS14680 [aryl-carrier protein] 7-carboxy-7-deazaguanine [acp]:NAD+ synthetase: urocanate molecule with oxo-C40:1-[acp] IEK_RS25640 L-proline acyl-CoA synthetase: acetate-- sulfur] cluster HAD family acetyl-CoA C- a 2',3'-cyclic acetyl-CoA C- 16S rRNA DNA polymerase/ acyl-CoA 3-oxoacyl-ACP carbonic arsenate IEK_RS08480 oxidoreductase: hydratase: ferredoxin- a 5'-OH end UDP-N-acetyl- D-alanine--D- 7-cyano-7-deazaguanine IEK_RS17385 [+ 2 isozymes] 2-amino-3- degradation IEK_RS17385 CoA ligase: hydrolase: acyltransferase: phosphate end 2'-5' RNA acyltransferase: (uracil(1498)-N(3))- 3'-5' exonuclease dehydrogenase: anhydrase: reductase (2R,4S)-2-methyl-2,4- beta-ketoacyl- -nitrite reductase: α alanine ligase: IEK_RS20945 [+ 4 isozymes] carboxymuconate- hutU IEK_RS04380 IEK_RS16400 IEK_RS09745 ligase: IEK_RS09745 methyltransferase: PolX: IEK_RS12080 IEK_RS27570 (thioredoxin) -D-muramoyl- synthase QueC: queC dihydroxydihydrofuran-3-one a long-chain [+ 4 isozymes] reductase: IEK_RS10510 IEK_RS25460 [acyl-carrier- 6-semialdehyde 4-imidazolone- γ N-citryl- pro [+ 6 isozymes] [+ 2 isozymes] IEK_RS13025 [+ 2 isozymes] 3 IEK_RS06055 IEK_RS04930 [+ 5 isozymes] : arsC L-alanyl- -D- 7-cyano-7-deazaguanine a palmitoleoyl-[acp] fatty acyl-CoA pro 2-methylbutanoyl- IEK_RS19880 a ligated tRNA an N - a cis-delta21-3-[+ 4 isozymes] [+ 2 isozymes] spermidine:3,4- N-citryl- protein] phosphatidylglycerol 5-propanoate AMP diphosphate (2E)-hexadecenoyl-CoA AMP diphosphate a (2R)-2- (7Z)- 3-oxohexanoyl- a nucleoside 5'- (2E,5Z)- glutamyl-meso-2,6- synthase QueC: queC CoA a halide anion acetyl-CoA 1498 CO H O arsenite D-alanyl-D-alanine spermidine:spermidine synthase proline nitrite hydroxy fatty acid tetradecenoyl-CoA with a 2'-5' linkage CoA methyluracil dodecenoyl-CoA hydroxyC40:1- 2 2 diaminopimelate dihydroxybenzoate biosynthesis I (plastidic) glycine cleavage imidazolonepropionase: monophosphate ligase: IEK_RS17390 II: fabF dehydrogenase: in 16S rRNA [acp] ligase: IEK_RS17375 preQ (2R,4S)-2-methyl-2,3,3,4- IEK_RS09640 0 IEK_RS02665 UDP-N- tetrahydroxytetrahydrofuran DHAP a [glycine-cleavage complex (S)-1-pyrroline- a 3-oxooctanoyl-[acp] 6 acetylmuramoyl- glycerol-3- acyl-CoA hydrolysis H protein] N -lipoyl-L-lysine glycine cleavage 5-carboxylate N-formimino- an O 6 - (6Z,9Z,12Z,15Z,18Z,21Z)-3- an (R)-2- (3E,5Z)-tetradeca- 3-oxopentanoyl- 3-oxo- palmitoleate 18-hydroxyoleate a [protein]- a [protein] Ser/Thr (S)-dihydroorotate lauroyl-CoA H O a cis-delta19-3- propionamide 1 phosphate system protein L-glutamate methylguanine oxotetracosahexaenoyl-CoA halocarboxylate 3,5-dienoyl-CoA CoA palmitoyl-CoA 2 D-serine tripeptide-- N -(3,4- 3-oxoacyl-ACP L-cysteine oxo-C38:1-[acp] N 8 ,N' 8 -citryl- dehydrogenase glycine cleavage H: gcvH acyl-CoA synthetase: in DNA acetyl-CoA C- HAD family acyl-CoA acetyl-CoA C- acetyl-CoA C- serine/threonine acyl-CoA amidase: D-alanyl-D- dihydroxybenzoyl)- reductase: a 2,3,4-saturated formimidoylglutamase: methylated-DNA-- 3-oxoacyl-ACP 8 bis(spermidine) (NAD(P)(+)): system protein IEK_RS09740 acyltransferase: hydrolase: thioesterase: acyltransferase: acyltransferase: protein kinase: dihydroorotase: thioesterase: IEK_RS17015 D-serine alanine ligase: N -citryl-spermidine IEK_RS10510 fatty acyl CoA glycine [protein]-cysteine S- reductase: IEK_RS19490 acyl-CoA H: gcvH L-glutamate-5- IEK_RS09645 IEK_RS16045 IEK_RS08290 IEK_RS09840 ammonia-lyase: IEK_RS25455 cleavage system [+ 4 isozymes] methyltransferase: IEK_RS09745 IEK_RS16400 IEK_RS17105 IEK_RS09745 IEK_RS09745 IEK_RS10510 amidase: [+ 4 isozymes] sn-glycerol thioesterase: semialdehyde IEK_RS18420 3,4-dihydroxybenzoyl- citryl- [+ 4 isozymes] protein T: gcvT IEK_RS09045 [+ 2 isozymes] [+ 6 isozymes] [+ 3 isozymes] [+ 2 isozymes] [+ 2 isozymes] [+ 4 isozymes] [+ 3 isozymes] IEK_RS17660 3-phosphate IEK_RS09840 glu AMP diphosphate 18-hydroxyoleoyl-CoA (4Z,7Z,10Z,13Z,16Z,19Z) a (2R)-2- (3E,5Z)- N-carbamoyl- a cis-delta19-3-[+ 4 isozymes] UDP-N-acetyl- citryl- bis(spermidine):3,4- a (3R)-3- L-glutamate a [protein]-S- acetyl-CoA a halide anion coenzyme A propanoyl-CoA acetyl-CoA myristoyl-CoA acetyl-CoA a [protein] (L-serine/L- laurate propanoate pyruvate [+ 3 isozymes] a [glycine-cleavage a guanine in DNA -docosahexaenoyl-CoA hydroxy fatty acid tetradecadienoate L-aspartate hydroxyC38:1- α-D-muramoyl- spermidine:spermidine dihydroxybenzoate hydroxyoctanoyl-[acp] glycerol-3- a 2,3,4-saturated a [glycine-cleavage gamma- methyl-L-cysteine threonine) phosphate complex H protein] N 6 - [acp] L-alanyl-γ-D- ligase: IEK_RS17390 ligase: IEK_RS17375 phosphate 1-O- fatty acid complex H protein] N 6 semialdehyde aminomethyldihydrolipoyl- glutamyl-meso-2,6- di-trans,octa-cis acyltransferase -dihydrolipoyl-L-lysine dehydrogenase: 1 L-lysine 4 diaminopimeloyl- -undecaprenyl N -(3,4- PlsY: an O - (6Z,9Z,12Z,15Z,18Z)-3- methyl (indol- 4-trans-3-oxo- methyl β-D-glucoside an insertion sequence pruA 7-hydroxylaurate a [protein]- maltoheptaose octanoyl-CoA acetyl-CoA oleoyl-CoA H O a cis-delta17-3- squalene dihydroxybenzoyl) IEK_RS15340 L-tryptophan methylthymine 2 D-cysteine D-alanyl-D-alanine phosphate L-cysteine oxotetracosapentaenoyl-CoA 3-yl)acetate undecenoyl-CoA 6-phosphate element IS30 oxo-C36:1-[acp] -N 8 ,N' 8 -citryl- a (2E)-oct-2-enoyl-[acp] degradation I acyl-CoA synthetase: acetyl-CoA C- glycogen/starch/ carboxylesterase: acetyl-CoA C- acetyl-CoA C- 6-phospho-beta- acyl-CoA glycerol-3- glu in DNA methylated-DNA-- transposase: 3-oxoacyl-ACP squalene- bis(spermidine) (via anthranilate) IEK_RS09740 acyltransferase: alpha-glucan IEK_RS02235 acyltransferase: acyltransferase: glucosidase: thioesterase: D-cysteine Carbohydrate Biosynthesis phosphate 1-O- [protein]-cysteine S- IEK_RS19135 reductase: -hopene petrobactin octanoyl-[acyl- L-threonine [+ 4 isozymes] IEK_RS09745 phosphorylase: carboxylesterase: IEK_RS01120 IEK_RS09745 IEK_RS22030 IEK_RS09840 cyclase: desulfhydrase: acyltransferase trp methyltransferase: [+ 9 isozymes] IEK_RS10510 synthase: carrier-protein] glycine cleavage degradation III (to IEK_RS03370 [+ 2 isozymes] IEK_RS11585 undecaprenyldiphospho- PlsY: IEK_RS09045 [+ 2 isozymes] IEK_RS09670 [+ 2 isozymes] [+ 2 isozymes] an insertion [+ 3 isozymes] [+ 4 isozymes] IEK_RS10075 gluconeogenesis I IEK_RS17375 reductase: system protein methylglyoxal) tryptophan 2,3- AMP diphosphate 7-hydroxylauroyl-CoA (4Z,7Z,10Z,13Z,16Z)- α-D-glucopyranose 2-trans- 3-oxodecanoyl- β-D-glucose a cis-delta17-3- N-acetylmuramoyl-L- PRPP biosynthesis CMP-pseudaminate biosynthesis α IEK_RS09850 a [protein]-S- acetyl-CoA maltohexaose MeOH (indol-3-yl)acetate acetyl-CoA MeOH sequence IS30 with oleate hop-22(29)-ene pyruvate UDP-N-acetyl- -D- H: gcvH dioxygenase: a thymine in DNA docosapentaenoyl-CoA 1-phosphate nonenoyl-CoA CoA 6-phosphate hydroxyC36:1- alanyl-γ-D-glutamyl-meso IEK_RS20945 a 1-acyl-sn methyl-L-cysteine integrated transposon mannosaminouronate petrobactin glycine thr L-glutamate kynA [acp] -2,6-diaminopimeloyl- (S)-malate D-ribose 5- UDP-N-acetyl-α-D-glucosamine -glycerol 3- N-Formyl-L- biosynthesis an octanoyl-[acp] cleavage system L-threonine 3- degradation II D-alanyl-D-alanine phosphate UDP-N-acetylglucosamine UDP-N-acetyl- phosphate kynurenine ribose-phosphate protein T: gcvT dehydrogenase: a [protein]- undecaprenyldiphospho- 4,6-dehydratase α-D-glucosamine 1-acyl-sn-glycerol- arylformamidase: 2-amino-6-[1-hydroxyethyl]- D-cellobiose all-trans- 3-oxooctanoyl- 3-oxo-(5Z)- dihomo γ- D-ribulose pyrophosphokinase: UDP-N- 3-oxoacyl-[acyl- IEK_RS23665 glu cob(I)alamin- maltopentaose methylsalicylate H O an aldehyde a cis-delta15-3- 6'-phosphate 2 L-tyrosine 5-phosphate muramoylpentapeptide beta-N- IEK_RS00155 (configuration-inverting) 3-phosphate L-2-amino-3- kynB 7-methyl-7,8-dihydropterin [corrinoid ATP retinyl palmitate CoA tetradecenoyl-CoA linolenoyl-CoA oxo-C34:1-[acp] malate acetylglucosamine carrier-protein] aspartate 6-phospho-beta- glycogen/starch/ carboxylesterase: acetyl-CoA C- acetyl-CoA C- carboxylesterase: acyl-CoA NAD(P)- phosphate ribulose- acetylglucosaminyltransferase: malate PRPP : IEK_RS26580 acyltransferase: oxobutanoate 2-amino-4-hydroxy-6- adenosyltranferase] 3-oxoacyl-ACP dehydrogenase: UDP-2-acetamido-2,6-dideoxy- 2-epimerase reductase: transaminase: ATP:cob(I)alamin glucosidase: alpha-glucan IEK_RS09670 acyltransferase: acyltransferase: IEK_RS02235 thioesterase: dependent alcohol protein-tyrosine- phosphate 3- IEK_RS06345 dehydrogenase: IEK_RS16360 L-kynurenine hydroxymethyldihydropteridine reductase: β-L-arabino-hex-4-ulose (non-hydrolyzing) IEK_RS08480 L-methionine IEK_RS19285 adenosyltransferase: IEK_RS22030 phosphorylase: IEK_RS09745 IEK_RS09745 IEK_RS17105 dehydrogenase: phosphatase: epimerase: [+ 2 isozymes] mdh diphosphokinase: folK carboxylesterase: carboxylesterase: IEK_RS10510 IEK_RS18345 : IEK_RS01900 1-acyl-sn-glycerol- degradation II asp adenosylcob(III)IEK_RS19620 IEK_RS03370 IEK_RS11080 IEK_RS08430 lipid II (meso UDP-4-amino-4, 6-dideoxy- UDP-N-acetyl-α- beta-ketoacyl- [1-(2-amino-7-methyl-4-oxo- [+ 2 isozymes] IEK_RS02235 [+ 2 isozymes] [+ 2 isozymes] IEK_RS09670 [+ 3 isozymes] IEK_RS25735 [+ 4 isozymes] 3-phosphate kynureninase: D-glucopyranose α-D-glucopyranose (3Z)-dodec- di-homo-γ- a cis-delta15-3- a [protein]- D-xylulose diaminopimelate N-acetyl-beta-L-altrosamine D-mannosamine [acyl-carrier- 7,8-dihydro-3H-pteridin- triphosphate alamin-[corrinoid D-glucopyranose maltotetraose palmitate all-trans-retinol acetyl-CoA hexanoyl-CoA acetyl-CoA MeOH salicylate an alcohol protein] acyltransferase: aminoacetone aspartate kynU adenosyltranferase] 6-phosphate 1-phosphate 3-enoyl-CoA linolenate hydroxyC34:1- L-tyrosine 5-phosphate containing) transaminase: pseC UDP-N-acetyl-D- met 6-yl)]ethyl diphosphate synthase IEK_RS25595 ammonia- [acp] oxaloacetate UDP-4-amino-4,6-dideoxy- mannosamine Aromatic Compound Biosynthesis a 1,2-diacyl- methionine β II: fabF lyase: aspA anthranilate pyruvate N-acetyl- -L-altrosamine dehydrogenase: sn-glycerol gamma-lyase: UDP-4-amino-4, 6-dideoxy- bacillibactin biosynthesis IEK_RS04435 aspartate an (R)-2- 6-trans-3-oxo- 3-oxododecanoyl- (-)-methyl L-fuculose phosphoenolpyruvate IEK_RS01485 3-phosphate (2Z)-2-aminobut- D-serine degradation cob(I)yrinate a,c- a glycogen palmitoleoyl-CoA propan-1-ol a cis-delta13-3- butanoate N-acetyl-beta-L-altrosamine chorismate biosynthesis I a 3-oxodecanoyl-[acp] ammonia- halocarboxylate CoA jasmonate 1-phosphate gly carboxykinase phosphoenolpyruvate UDP-N-acetyl-α-D- phosphatidate 2-enoate methylglyoxal ATP diamide-[corrinoid a tRNA precursor CTP ATP tridecenoyl-CoA oxo-C32:1-[acp] N-acetyltransferase: pseH lyase: aspA HAD family glycogen/starch/ acetyl-CoA C- acetyl-CoA C- carboxylesterase: fuculose acyl-CoA NAD(P)- (ATP): pckA mannosaminuronate cytidylyltransferase: adenosyltranferase] 3-oxoacyl-ACP synthase: IEK_RS12015 chorismate 3-oxoacyl-ACP ATP:cob(I)alamin CCA tRNA hydrolase: alpha-glucan acyltransferase: acyltransferase: IEK_RS02235 phosphate dependent alcohol butyrate kinase: glycine UDP-2,4-diacetamido-2,4,6- D-erythrose 4-phosphate IEK_RS08625 D-serine dehydrogenase: reductase: β reductase: fumarate adenosyltransferase: nucleotidyltransferase: IEK_RS16400 phosphorylase: IEK_RS01120 IEK_RS09745 aldolase: dehydrogenase: IEK_RS06885 oxidase trideoxy- -L-altropyranose isochorismate phospho-2-dehydro- D-serine carboxylesterase: IEK_RS12080 IEK_RS10510 phosphoenol IEK_RS10510 a CDP- IEK_RS19620 a tRNA IEK_RS19335 IEK_RS03370 IEK_RS24850 IEK_RS25735 ThiO: thiO UDP-2,4-diacetamido- UDP-α-D-glucose biosynthesis I synthase EntC: 3-deoxyheptonate ammonia-lyase: a [corrinoid adenosyl-cob(III) [+ 6 isozymes] [+ 2 isozymes] [+ 2 isozymes] IEK_RS09670 [+ 5 isozymes] [+ 4 isozymes] butanoyl pyruvate diacylglycerol 2-iminobutanoate L-threonine triphosphate containing a an (S)-2- α-D-glucopyranose 4-trans- (2E,9Z)- a cis-delta13-3- 2,4, 6-trideoxy-beta- α IEK_RS15825 aldolase: [+ 4 isozymes] IEK_RS18420 adenosyltransferase] yrinate a,c-diamide a halide anion maltotetraose acetyl-CoA acetyl-CoA decanoyl-CoA MeOH (-)-jasmonate DHAP (S)-lactaldehyde 1-propanal phosphate glyoxylate enolase: UDP- -D-galactose CDP-diacylglycerol-- degradation II 2-aminoprop- 3' CCA end hydroxycarboxylate 1-phosphate undecenoyl-CoA hexadecenoyl-CoA hydroxyC32:1- UDP-N-acetyl-D- L-altropyranose isochorismate IEK_RS04305 a (3R)-3- IEK_RS02210 biosynthesis D-glucopyranose 6-phosphate glycerol-3-phosphate 3- 2-enoate [acp] glucosamine biosynthesis I hydrolase: pseG hydroxydecanoyl-[acp] phosphoglucomutase: synthase: 3-deoxy-7- phosphatidyltransferase: 2-phospho- D-glucopyranose 2,4-diacetamido-2,4,6- UDP-α-D-glucose IEK_RS03405 phosphoheptulonate thr β IEK_RS03080 pgsA L-phenylalanine degradation I (aerobic) L-threonine 3- 967 D-glycerate trideoxy- -L-altropyranose phosphatidylglycerophosphate an (S)-2- 2251 6-cis, 3-oxo- a cytosine 3-oxo- (7Z)- 6-phosphate UDP-glucose synthase: 1-(3-sn- 2-oxobutanoate guanosine in 23S rRNA propanoyl-CoA H O pyridoxal a cis-delta11-3- a chitodextrin glucose-6- α-D-glucopyranose 1-phosphate isochorismate dehydrogenase: halocarboxylate tridecenoyl-CoA in 16S rRNA myristoyl-CoA 2 hexadecenoyl-CoA D-ala 2,3-bisphosphoglycerate- pseudaminic acid 4-epimerase: IEK_RS12755 (1-octadecenoyl(9Z), 2-palmitoyl) ATP cob(II)inamide oxo-C30:1-[acp] phosphatidyl) (6R)-4a-hydroxy- IEK_RS23665 2-iminopropanoate HAD family 23S rRNA acetyl-CoA C- 16S rRNA acetyl-CoA C- acyl-CoA acyl-CoA 3-oxoacyl-[acyl- chitinase: independent phosphate synthase: pseI 3-deoxy-D-arabino- L-2-amino-3- 3-oxoacyl-ACP IEK_RS25225 UTP--glucose-1-phosphate -sn-glycerol tetrahydrobiopterin phosphatidylglycerophosphatase ATP:cob(I)alamin hydrolase: (guanosine(2251)-2'- acyltransferase: (cytosine(967)-C(5) acyltransferase: thioesterase: dehydrogenase: carrier-protein] IEK_RS24620 glycine phosphoglycerate isomerase: isochorismatase: heptulosonate 7-phosphate a (2E)-dec-2-enoyl-[acp] 4a-hydroxytetrahydrobiopterin reductase: pseudaminate [+ 2 isozymes] uridylyltransferase: galU 3-phosphate oxobutanoate A: IEK_RS02925 adenosyltransferase: IEK_RS16400 IEK_RS01120 IEK_RS09745 IEK_RS09840 IEK_RS12080 chitinase: oxidase IEK_RS03185 UDP-α-D-galactose IEK_RS15815 dehydratase: IEK_RS05825 O)-methyltransferase )-methyltransferase reductase: IEK_RS10510 mutase: IEK_RS02205 UTP--glucose-1-phosphate 3-dehydroquinate phenylalanine 4- IEK_RS09135 ThiO: thiO F6P (2S,3S)-2,3- decanoyl-[acyl- phosphatidylglycerophosphatase glycine C- IEK_RS19620 [+ 6 isozymes] RlmB: IEK_RS26165 [+ 2 isozymes] RsmB: IEK_RS08405 [+ 2 isozymes] [+ 3 isozymes] [+ 5 isozymes] IEK_RS08480 [+ 4 isozymes] 3-phospho- synthase: monooxygenase: 1-oleoyl-2-palmitoyl- triphosphate an (S)-2- 2-O-methylguanosine 2251 4-cis- a 5-methylcytosine 967 (2E,7Z)- a cis-delta11-3- N,N'- uridylyltransferase: galU A: IEK_RS02925 acetyltransferase: adenosylcobinamide acetyl-CoA acetyl-CoA lauroyl-CoA propanoate pyruvate dihydroxy-2,3- carrier-protein] IEK_RS05830 phosphatidylglycerol a halide anion 4-pyridoxolactone hydroxyC30:1- diacetylchitobiose D-glycerate glutamine-- IEK_RS19430 an L-1- IEK_RS23670 pyruvate hydroxycarboxylate in 23S rRNA undecenoyl-CoA in 16S rRNA hexadecenoyl-CoA CMP-pseudaminate UDP-α-D-glucose dihydrobenzoate reductase: fructose-6- [acp] phosphoglycerate 2,3-dihydro-2,3- IEK_RS20945 phosphatidyl- (6R)-L-erythro-5,6,7,8- L-erythro-7,8- phosphate 3-dehydroquinate gly kinase: pgk dihydroxybenzoate sn-glycerol tetrahydrobiopterin dihydrobiopterin transaminase type II 3- a decanoyl-[acp] UDP-N-acetyl-α-D-muramoyl- N-acetyl-D-glucosaminyl-N- (5Z,8Z,11Z,14Z,17Z)-3- (+)-7-epi- dehydrogenase: L-alanine D-alanyl-D-alanine maltohexaose maltoheptaose maltotetraose a 3-oxoacyl-CoA H O palmitoyl-CoA H O urea-1-carboxylate an L-cysteinyl- orotidine 5'- a D-hexose (isomerizing) acetylmuramoyl-L-alanyl-D-glutamyl- 2 2 13-DPG dehydroquinate L-alanyl-γ-D-glutamyl-L-lysine oxodocosapentaenoyl-CoA jasmonoyl-CoA Cys IEK_RS15830 degradation IV L-glutamine alpha-glucosidase: alpha-glucosidase: [tRNA ] phosphate : glmS dehydratase: aroQ 3-oxoacyl-[acyl- L-asparagine UDP-N-acetylmuramoyl- 6-carboxy-L-lysyl-D-alanine glycogen/starch/ 3-oxoacyl-[acyl- acetyl-CoA C- acyl-CoA acyl-CoA allophanate dTDP-L-rhamnose biosynthesis 2,3- degradation I LD-carboxypeptidase: IEK_RS24695 IEK_RS24695 aminoacyl- orotidine-5'- glucokinase: D-glucosamine degradation I tripeptide--D-alanyl- alpha-glucan carrier-protein] acyltransferase: thioesterase: thioesterase: hydrolase glyceraldehyde- dihydroxybenzoate carrier-protein] IEK_RS17545 tRNA phosphate IEK_RS06290 α 3-dehydroshikimate ala alpha-glucosidase: alpha-glucosidase: phosphorylase: reductase: IEK_RS09745 IEK_RS17105 IEK_RS09840 subunit 1: triose- 3-phosphate 6-phosphate -D-glucopyranose reductase: fatty acid elongation -- saturated D- alanine ligase: N-acetyl-D-glucosaminyl-[+ 2 isozymes]N- hydrolase: decarboxylase: (2,3- gln IEK_RS07635 IEK_RS07635 IEK_RS03370 IEK_RS08480 [+ 3 isozymes] IEK_RS12115 phosphate dehydrogenase: 1-phosphate gly IEK_RS08480 alanine asn IEK_RS25455 acetylmuramoyl-L-alanyl-D- [+ 2 isozymes] [+ 3 isozymes] IEK_RS00150 pyrF D-hexose 6- phosphoglucosamine glucose-1-phosphate dihydroxybenzoyl) shikimate Alcohol Degradation CTP synthase: UDP-N-acetyl-α-D-muramoyl-L-alanyl- D-ala α-D-glucopyranose (3R,5Z,8Z,11Z,14Z,17Z)-3- (+)-7-epi- isomerase: gap dehydrogenase: ald D-glucopyranose maltopentaose D-glucopyranose maltohexaose maltotriose acetyl-CoA an acyl-CoA palmitate CO ammonium Cys UMP phosphate mutase: IEK_RS25785 dehydrogenase: beta-ketoacyl- IEK_RS15495 asparaginase: γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine glutamyl-6-carboxy-L-lysine 1-phosphate hydroxydocosapentaenoyl-CoA jasmonate 2 a tRNA cys IEK_RS02200 thymidylyltransferase: adenylate synthase: an acetoacetyl-[acp] alanine D-glyceraldehyde α-D-glucosamine IEK_RS05940 [acyl-carrier- [+ 13 isozymes] IEK_RS19535 DHAP rfbA IEK_RS15820 glycerol and dehydrogenase: ald 3-phosphate 1-phosphate dTDP-α-D-glucose (2,3- protein] glu asp shikimate glycerophosphodiester degradation pyruvate dihydroxybenzoyl) synthase bifunctional N- dTDP-glucose 4,6- UDP-N-acetylmuramoyl-L- 3-(4- 3-oxo-(5Z)- (5Z)- UDP-yelosamine II: fabF a sulfurated a ferrocytochrome maltopentaose 2-oxoadipate a kanamycin butan-1-ol Ala (S)-malate chitin acetylglucosamine- dehydratase: rfbB (glycyl)adenylate adenylate shikimate kinase: a glycerophosphodiester SAM dethiobiotin alanyl-γ-D-glutamyl-meso-2,6- palmitoyl-CoA hydroxyphenyl) dodecenoyl-CoA a glycyl-[tRNA ] biosynthesis [sulfur carrier] b tetradecenoyl-CoA 5 alpha-glucosidase: pyruvate acetyl-CoA C- aminoglycoside acyl-CoA chitinase: 1-phosphate dTDP-glucose 4,6- IEK_RS06530 a 3-oxoacyl-[acp] biotin diaminopimeloyl-D-alanineLD-carboxypeptidase: acyl-CoA 2-oxoglutarate NAD(P)- D-aminoacyl- malate:quinone fructose-1,6- thr a 3-oxododecanoyl-[acp] IEK_RS24695 phosphotransferase: IEK_RS24620 uridyltransferase/ UDP-N-acetyl- synthase BioB: IEK_RS17545 desaturase: 4-hydroxyphenylpyruvate dehydrogenase acyltransferase: dehydrogenase: dependent alcohol oxidoreductase: bisphosphate dehydratase: rfbB α glycerol tRNA -D-glucosamine shikimate 3-phosphate glycerophosphoryl alpha-glucosidase: E1 component: IEK_RS09745 IEK_RS16390 IEK_RS15060 dehydrogenase: chitinase: aldolase, glucosamine- dTDP-4-dehydro-6- UDP-N- a 2,3- 3-oxoacyl-ACP Carboxylate Degradation IEK_RS07120 UDP-N-acetyl-α-D-muramoyl-[+ 2 isozymes] IEK_RS24760 dioxygenase: hppD deacylase: IEK_RS12680 diester an unsulfurated a ferricytochrome IEK_RS07635 IEK_RS20735 [+ 2 isozymes] [+ 3 isozymes] [+ 5 isozymes] IEK_RS25735 IEK_RS09135 class II: fba 1-phosphate deoxy-α-D-glucopyranose acetylglucosamine a glycyl-[DhbF dihydroxybenzoyl- reductase: met 5'-deoxyadenosine biotin L-alanyl-γ-D-glutamyl- D-ala palmitoleoyl-CoA IEK_RS05585 3-phosphoshikimate 1- beta- glycerol phosphodiesterase: [sulfur carrier] b homogentisate (3Z)-dec-3- a kanamycin (2E,5Z)- oxaloacetate acetyltransferase: non-ribosomal [DhbB aryl- 3-ketoacyl-ACP 5 D-glucopyranose maltotetraose glutaryl-CoA NADH CO acetyl-CoA butan-1-al Ala a chitodextrin dTDP-4- 4,6-dehydratase IEK_RS10510 meso-2,6-diaminopimelate 2 a tRNA gly carboxyvinyltransferase: ketoacyl- kinase: IEK_RS23805 acetyl-CoA fermentation to butanoate II enoyl-CoA 3'-phosphate tetradecenoyl-CoA glmU dehydrorhamnose (configuration- (L-threonyl) peptide synthase] carrier protein] [+ 4 isozymes] reductase: pyruvate fermentation to acetate IV D-gluconate aroA [acyl- glpK [+ 4 isozymes] N-acetyl-α-D- 3,5-epimerase: rfbC retaining): adenylate IEK_RS17500 degradation 5-enolpyruvoyl- a (3R)-3- carrier- acetyl-CoA β-D-fructose 1,6- glucosamine dTDP-4- IEK_RS26580 [+ 4 isozymes] UDP-2-acetamido- shikimate 3-phosphate hydroxydodecanoyl-[acp] protein] sn-glycerol pyruvate D-gluconate 4a-hydroxy-N 10 - a dimer of non- MoO - a uridine 2604 acibenzolar- 3-[(4'- bisphosphate 1-phosphate O-acetyl-L- aci-nitroethane 2 cis-vaccenoyl-CoA Asx dehydrorhamnose α a (3R)-3- methanethiol adjacent 2'- methylsulfanyl) butan-1-ol a tRNA asp methylglyoxal ferroheme o 2,6-dideoxy- -D- a 2,3- a 2,3,4-saturatedsynthase 3-phosphate gluconokinase: homoserine formyltetrahydrofolate ν molybdopterin ATP in 23S rRNA S-methyl fructose- bifunctional N- 3,5-epimerase: rfbC chorismate synthase: hydroxyacyl-[acyl- phosphate acetyl-CoA C- nitronate h 23S rRNA carboxylesterase: butyl]malate acyl-CoA NAD(P)- xylo-hex-4-ulose an L-threonyl- dihydroxybenzoyl- II: fabF gntK O-acetylhomoserine deoxycytidines cofactor aspartate-- glyoxalase: heme A bisphosphatase acetylglucosamine- IEK_RS19435 fatty acyl-[acp] acetyltransferase: pta acyltransferase: formate C- 4a-hydroxytetrahydrobiopterin molybdenum cofactor 3-isopropylmalate dTDP-4-dehydro- UDP-4-amino- carrier protein] [+ 2 isozymes] monooxygenase: in DNA deoxyribodipyrimidine pseudouridine(2604) IEK_RS02235 dehydrogenase: dependent alcohol tRNA(Asn) IEK_RS14555 synthase: [DhbF non- glycyl-[DhbF acetyltransferase: aminocarboxypropyltransferase: dehydrogenase: class II: glpX 1-phosphate β-L-rhamnose 4, 6-dideoxy- chorismate synthase: IEK_RS09745 D-gluconate dehydratase: IEK_RS05825 IEK_RS20165 guanylyltransferase: synthase RluF: carboxylesterase: IEK_RS12080 dehydrogenase: ribosomal non-ribosomal a (2E)-dodec- pflB IEK_RS00825 [unspecified photo-lyase: ligase: [+ 10 isozymes] IEK_RS08000 fructose- uridyltransferase/ IEK_RS12760 [+ 3 isozymes] 6-phosphate adenylyl IEK_RS03885 IEK_RS15740 leuB IEK_RS25735 dTDP-4- N-acetyl-beta- peptide synthase] peptide synthase] acetyl phosphate an N 10 -formyl- degradation nitrite acetaldehyde IEK_RS11905 IEK_RS09670 [+ 5 isozymes] IEK_RS16470 2-enoyl-[acp] DHAP acetate met a 2'-deoxycytidine 2604 7-(methylsulfanyl) ferroheme a bisphosphatase glucosamine- L-altrosamine molybdenum a pseudouridine (2E,11Z)- butan-1-al an L-aspartyl- (R)-lactate dehydrorhamnose chorismate 7,8-dihydrofolate products] in DNA MeOH acibenzolar -2-oxoheptanoate 1-phosphate dodecanoyl- formate cofactor in 23S rRNA octadecenoyl-CoA [tRNA Asx ] class II: glpX reductase: rfbD transaminase: acetate kinase: acetoacetyl-CoA acetyl-CoA acetyltransferase: [acyl-carrier- dTDP-4- pseC IEK_RS04520 F6P glmU protein] phosphate dehydrorhamnose UDP-2-acetamido- a 2,3- acetoacetyl- UDP-N-acetyl- 4-amino-2,4,6- reductase: CoA reductase: acetyltransferase: pta a 1-phosphatidyl- UDP-4-amino-D-fucose all-trans- 3-[(6'- (7Z)- (3R)-3- glucose-6- reductase: rfbD dihydroxybenzoyl- a trans-2- acetate a lipid II maltotriose wound RNA citrate α-D-glucosamine trideoxy-α- IEK_RS20945 a 2,3,4-saturated IEK_RS20455 DL-allothreonine 1D-myo-inositol retinyl palmitate methylsulfanyl) tetradecenoyl-CoA hydroxypentanoyl- cys phosphate glycyl-L-arginyl- Metabolic Regulator enoyl-[acyl- 4'-phosphopantetheine ATP UDP-4-amino-4, 6- dTDP-β-L-rhamnose acetyl phosphate D-Ala-D-Ala 1-phosphatidylinositol alpha-glucosidase: carboxylesterase: hexyl]malate acyl-CoA CoA D-galactose Biosynthesis fatty acyl-[acp] carrier protein] serine dideoxy-N-acetyl- DNA/RNA aconitate isomerase: [DhbF non-ribosomal a dodecanoyl-[acp] (3R)-3-hydroxybutanoyl-CoA carboxypeptidase phosphodiesterase: phosphopantetheine IEK_RS24695 IEK_RS02235 3-isopropylmalate dehydrogenase: acetoacetyl- cysteine hydroxymethyltransferase: beta-L-altrosamine helicase: hydratase IEK_RS03185 peptide synthase] ppGpp biosynthesis 2,3,4-saturated VanY: IEK_RS03445 IEK_RS08940 adenylyltransferase: alpha-glucosidase: dehydrogenase: IEK_RS12080 CoA reductase: dioxygenase: acetate kinase: a N-acetylglucosamine--N- IEK_RS01260 D-myo-inositol transaminase: pseC carboxylesterase: IEK_RS01930 AcnA: acnA D-glucopyranose fatty acyl- a 1,2-diacyl- IEK_RS08085 IEK_RS07635 IEK_RS09670 leuB [+ 5 isozymes] IEK_RS20455 IEK_RS14270 IEK_RS04520 D-ala acetylmuramyl-(tetrapeptide) gly acetaldehyde 1,2-cyclic 3'-dephospho- UDP-4-dehydro-6- 9-(methylsulfanyl) 3-oxopentanoyl- 6-phosphate UDP-yelosamine 3-oxoacyl-[acyl- [acp]:NAD+ sn-glycerol (2E,7Z)- an unwound RNA D-threo-isocitrate pppGpp pyrophosphoryl-undecaprenol phosphate CoA D-glucopyranose maltose deoxy-α-D-glucose palmitate a retinol -2-oxononanoate CoA 3-sulfino-L-alanine carrier-protein] oxidoreductase: acetate tetradecenoyl-CoA bacillibactin reductase: IEK_RS20945 crotonyl-CoA GTP IEK_RS08480 laurate guanosine 3'- acyl-CoA pyruvate decarboxylation to acetyl CoA pyrophosphokinase: a 2,3,4-saturated lipid II (meso (6R)-L-erythro 3-[(5'- (2Z,4E)-2- beta-ketoacyl- 10 an L-methionyl- a ring-opened 7- a monocarboxylic a double IEK_RS21035 diphosphate 5'- acyl-CoA dehydrogenase: an N - a peptide with a [EntF L-seryl- methylsulfanyl) oleoyl-CoA hydroxyhexa- pyruvate Met methylguanine in DNA CTP 1,2-diacyl-sn- diaminopimelate -5,6,7,8- phe coenzyme A acid amide stranded DNA triphosphate 3'- [acyl-carrier- synthetase: IEK_RS12080 a [pyruvate dehydrogenase formyltetrahydrofolate [initiator tRNA ] leader sequence carrier protein] [+ 3 isozymes] 6 DNA- glycerol 3-phosphate pentyl]malate acyl-CoA 2,4-dienedioate amidase: protein] E2 protein] N -lipoyl-L-lysinepyruvate methionyl-tRNA phosphatidate containing)peptidoglycan signal peptidase tetrahydrobiopterin phenylalanine 4- holo-ACP DNA gyrase pyruvate diphosphatase: IEK_RS09740 [+ 5 isozymes] formamidopyrimidine 3-isopropylmalate dehydrogenase: 4-oxalocrotonate IEK_RS17015 synthase dehydrogenase formyltransferase: cytidylyltransferase: transglycosylase: I: IEK_RS20645 monooxygenase: synthase: subunit A: carboxylase: IEK_RS05580 [+ 4 isozymes] biotin-carboxyl carrier glycosylase: mutM dehydrogenase: IEK_RS12080 tautomerase: amidase: II: fabF butanoyl-CoA (acetyl- an N-formyl- IEK_RS08400 2,6-diamino-4- IEK_RS08625 lipid II (meso di-trans,octa-cisIEK_RS24040 [+ 7 isozymes] IEK_RS05830 a holoIEK_RS25435-[EntF IEK_RS00370 pyc protein assembly dihydrolipoyl pyruvate an apurinic site a CDP-2,3,4-saturated- (6R)-6,7- leuB [+ 5 isozymes] IEK_RS00965 IEK_RS17660 lauroyl-CoA transferring) L-methionyl- a tetrahydrofolate hydroxy-5-(N-methyl) diaminopimelate -undecaprenyl a leader sequence a peptide tyr 3',5'-ADP L-seryl-carrier a negatively dehydrogenase: within DNA diacylglycerol 8-(methylsulfanyl) (2E,9Z)- (3E)-2-oxohex- oxaloacetate a [biotin carboxyl- E1 component met dihydrobiopterin a monocarboxylate GTP ppGpp lpdA [initiator tRNA ] formamidopyrimidine containing) diphosphate protein] -2-oxooctanoate octadecenoyl-CoA 3-enedioate supercoiled DNA a 3-oxotetradecanoyl- carrier protein]-L-lysine subunit [acp] [+ 2 isozymes] biotin-- alpha: pdhA nucleoside- 3-oxoacyl-ACP [acetyl-CoA- butanoate 2-phospho-4-(cytidine 5'- 3-aci- a dimer of adjacent cytidine 2',3'-cyclic 3-[(3'- 3,22-dioxochol- a 2,3,4- (indol-3-yl) (indol-3- GTP a ferrocytochrome formamide diphosphate reductase: carboxylase] diphospho)-2-C-methyl-D-erythritol nitropropanoate thymidine and 2'- hν a pimeloyl-[acp] ala stearoyl-CoA monophosphate VibB coenzyme A methylsulfanyl) 4-en-24-oyl-CoA saturated (3R)-3- acetamide pyrophosphokinase: a [pyruvate dehydrogenase a [pyruvate dehydrogenase b yl)pyruvate 2-C-methyl-D-erythritol 5 2',3'-cyclic-nucleotide kinase: bifunctional (p)ppGpp IEK_RS10510 ligase: 6 nitronate deoxycytidine in DNA propyl]malate acetyl-CoA C- hydroxyacyl-CoA amidase: phosphatidylglycerol E2 protein] N - E2 protein] N 6 -S- deoxyribodipyrimidine 8-amino-7- acyl-CoA holo-ACP indolepyruvate IEK_RS21035 2,4-cyclodiphosphate monooxygenase: 2'-phosphodiesterase: 3-isopropylmalate acetoacetyl- formamidase: IEK_RS19440 synthetase/guanosine- [+ 4 isozymes] IEK_RS19330 oxononanoate desaturase: synthase: acyltransferase: IEK_RS17015 decarboxylase: [+ 2 isozymes] biosynthesis II (non-plastidic) superpathway of acetate dihydrolipoyl-L-lysine acetyldihydrolipoyl-L-lysine synthase: IEK_RS26190 photo-lyase: IEK_RS13815 dehydrogenase: CoA reductase: amiF 3',5'-bis(diphosphate) 3'- a (3R)-3- a [biotin carboxyl- IEK_RS20165 synthase: bioF IEK_RS01120 amidase: utilization and formation [unspecified IEK_RS11905 IEK_RS24760 IEK_RS25435 leuB IEK_RS20455 IEK_RS15285 pyrophosphohydrolase: hydroxytetradecanoyl- carrier protein]-N 2-C-methyl-D-erythritol- adjacent thymidine-2'- 8-amino-7- a ferricytochrome [+ 2 isozymes] a holo-[VibB aryl- [+ 2 isozymes] IEK_RS17660 DHAP CMP degradation nitrite 3-oxopropanoate acyl-carrier protein oleoyl-CoA 3',5'-ADP 6-(methylsulfanyl) a 2,3,4-saturated (indol-3-yl) IEK_RS05580 [acp] 6 -biotinyl-L-lysine 2,4-cyclodiphosphate deoxycytidine in DNA oxononanoate b 3'-cmp carrier protein] 3-oxo-4-pregnene- formate products] 5 (indol-3-yl)acetate acetaldehyde glycerol-3- acetate acetate-- -2-oxohexanoate 20-carboxyl-CoA 3-oxoacyl-CoA GDP phosphate lipoate CoA ligase: acetyltransferase: dehydrogenase acetate kinase: acetyl-CoA Fatty Acid and IEK_RS04380 lpdA (3R)-3- (NAD(P)(+)): a [biotin carboxyl- IEK_RS04520 a single phosphoenol an [HPr]- a dimer of adjacent a peptide with (9Z,12Z,15Z,18Z)-3- uridine 746 a supercoiled a (2E)-tetradec- Lipid Degradation ν a 2-oxo uroporphyrinogen-I stearoyl-CoA H O 2-deoxy-D-ribose IEK_RS19490 carrier-protein dimer]- stranded DNA pyruvate L-histidine 2'-deoxycytidine and h L-ornithine an N-terminal hydroxyoctadecanoyl- 2 leu carboxylate oxotetracosatetraenoyl-CoA in 23S rRNA duplex DNA 2-enoyl-[acp] sn-glycerol 6 exodeoxyribonuclease phosphoenolpyruvate- CoA acyl-CoA N -biotinyl-L-lysine fatty acid β-oxidation I thymidine in DNA deoxyribodipyrimidine ornithine Xaa-L-prolineleucyl acetoacetyl- uroporphyrinogen 23S rRNA helicase: 3-phosphate acetyl phosphate acetyl-CoA acetoacetyl- leucine ribokinase: myristoyl-[acyl- VII large subunit: -protein photo-lyase: CoA reductase: thioesterase: pseudouridine acetyl-CoA acetyl-CoA aminotransferase: aminopeptidase: decarboxylase: dehydrogenase: IEK_RS21710 rbsK carrier-protein] glycerol-3- IEK_RS06800 phosphotransferase: ptsP CoA reductase: IEK_RS09840 synthase F: carboxylase a (3Z)-alk-3- an [HPr protein]- IEK_RS11905 IEK_RS21285 a peptide with IEK_RS03070 IEK_RS20455 IEK_RS21590 [+ 4 isozymes] carboxylase a single-stranded a ribonucleoside π adjacent 2'-deoxycytidine- IEK_RS20455 IEK_RS06880 reductase: phosphate 1-O- biotin enoyl-CoA N -phospho- pyruvate L-glutamate-5- a proteinogenic a proteinogenic (3R,9Z,12Z,15Z,18Z)-3- [+ 3 isozymes] IEK_RS04940 a single 2-deoxy-D-ribose carboxyl: oligodeoxyribonucleotide 5'-monophosphate thymidine in DNA an N-terminal coproporphyrinogen I 3-oxooctadecanoyl- 4-methyl-2- a pseudouridine 746 IEK_RS20945 acyltransferase carboxylase phosphate L-histidine semialdehyde amino acid amino acid hydroxytetracosatetraenoyl-CoA stearate stranded DNA 5-phosphate IEK_RS04700 ∆ 3 ∆ 2 L-proline CoA oxopentanoate in 23S rRNA PlsY: subunit: -cis- -trans- acetyltransferase: pta a myristoyl-[acp] accA IEK_RS15340 IEK_RS15055 enoyl-CoA acetyl-CoA isomerase: glycerol-3- acetyl-CoA a dimer of non-adjacent a dimer of non- 3-phenyl-2- a single 3-phospho- a (2E,4E)- 3-oxoacyl-[acyl- IEK_RS02680 L-carnitine (S)-4-amino-5- glu maltose 2-hydroxyisobutyramide phytol chitosan phosphate 1-O- carboxylase 2'-deoxycytidine and hν adjacent pyrimidine hν oxopropanoate stranded DNA D-glycerate a tRNA ile dienoyl-CoA carrier-protein] carboxylase oxopentanoate carboxyltransferase thymidine in DNA carnitine-CoA nucleosides in DNA alpha-glucosidase: amidase: NAD(P)- 2,4-dienoyl- acyltransferase biotin a (2E)-2- deoxyribodipyrimidine deoxyribodipyrimidine 3-phosphoglycerate glutamyl-tRNA chitosanase: reductase: subunit alpha: ligase: IEK_RS00265 4-hydroxyphenylpyruvate deoxyribonuclease IEK_RS24695 IEK_RS17015 leucine dependent alcohol PlsY: carboxylase acyl-CoA enoyl-CoA photo-lyase: photo-lyase: dehydrogenase: reductase: CoA reductase: IEK_RS08480 IEK_RS11735 dioxygenase: hppD IV: IEK_RS06180 alpha-glucosidase: dehydrogenase: IEK_RS14090 IEK_RS09850 subunit: accC synthetase: IEK_RS11905 IEK_RS11905 IEK_RS11485 IEK_RS05290 amidase: dehydrogenase: IEK_RS07755 beta-ketoacyl- a 2,3,4-saturated enoyl-CoA a 2'-deoxycytidine a pyrimidine an L-glutamyl- IEK_RS07635 IEK_RS06880 a chitosan a 1-acyl-sn a [carboxyl-carrier coenzyme A IEK_RS17385 a thymidine in DNA diphosphate AMP L-carnitinyl-CoA (2-hydroxyphenyl) IEK_RS17660 IEK_RS25735 a (2E)-2- [acyl-carrier- fatty acid acyl-CoA hydratase: in DNA nucleoside in DNA a 5'-phosphooligonucleotide 3-phosphooxypyruvate [tRNA Glu ] 2-hydroxy-2- (S)-3-methyl-2- fragment -glycerol 3- protein dimer]-N 6 - [+ 4 isozymes] a 2,3,4- acetate D-glucopyranose phytenal enoyl-CoA protein] dehydrogenase: IEK_RS02680 methylpropanoate oxopentanoate phosphate carboxybiotinyl-L-lysine saturated (3R)-3- synthase 1-acyl-sn-glycerol- IEK_RS15060 a 2,3,4- hydroxyacyl-CoA II: fabF a 2,3,4-saturated 3-phosphate [+ 5 isozymes] saturated (3S)-3- a dimer of non-adjacent a dimer of adjacent uridine 2'3'-cyclic fatty acyl CoA 10 (9Z,12Z,15Z,18Z,21Z)-3- D-ribulose L-gulono- a supercoiled a (2E,4Z)- acyltransferase: hydroxyacyl-CoA ν isobutanoate ν an N - L-arabinitol ethanol cyanate a 3-oxohexadecanoyl- thymidine and 2'- h pyrimidine h phe oxotetracosapentaenoyl-CoA monophosphate 5-phosphate 1,4-lactone duplex DNA dienoyl-CoA IEK_RS16360 3-hydroxyacyl-CoA formyltetrahydrofolate 2',3'-cyclic-nucleotide NAD(P)- [acp] deoxycytidine in DNA deoxyribodipyrimidine acetate--CoA ligase: nucleosides in DNA deoxyribodipyrimidine phenylalanine 4- acetoacetyl- NAD(P)- SMP-30/ ATP-dependent 2,4-dienoyl- cyanase: 1-acyl-sn-glycerol- dehydrogenase: IEK_RS04380 2'-phosphodiesterase: phosphoribulokinase: dependent alcohol dependent alcohol gluconolactonase/ DNA helicase cynS 3-oxoacyl-ACP photo-lyase: photo-lyase: monooxygenase: CoA reductase: CoA reductase: 3-phosphate fatty acid IEK_RS01125 IEK_RS13815 IEK_RS11445 dehydrogenase: dehydrogenase: LRE family protein: RecQ: reductase: acetyl-CoA C- IEK_RS11905 IEK_RS11905 IEK_RS05830 IEK_RS20455 IEK_RS07755 CO ammonium a 2'-deoxycytidine isobutanoyl-CoA AMP diphosphate two adjacent pyrimidine 4a-hydroxy-N 10 - [+ 2 isozymes] IEK_RS25735 IEK_RS25735 IEK_RS14770 IEK_RS19590 2 acyltransferase: biosynthesis initiation I a 2,3,4-saturated acyltransferase:a 2,3,4-saturated a thymidine in DNA tyr (3R,9Z,12Z,15Z,18Z,21Z)-3- D-ribulose-1,5- a (3E)-3- IEK_RS10510 in DNA nucleosides in DNA formyltetrahydrofolate L-arabinopyranose a single IEK_RS25595 fatty acyl CoA IEK_RS09745 3-oxoacyl-CoA hydroxytetracosapentaenoyl-CoA 3'-UMP bisphosphate acetaldehyde L-gulonate enoyl-CoA [+ 4 isozymes] a 1,2-diacyl- acetyl-CoA stranded DNA Nucleoside and Nucleotide Biosynthesis a (3R)-3- [+ 2 isozymes] sn-glycerol acetyl-CoA hydroxyhexadecanoyl- 3-phosphate carboxylase carboxyl: a [glycine-cleavage a debranched 2-trans, 4-trans uridine superpathway of pyrimidine ribonucleosides salvage [acp] orotidine 5'- (3R,7Z,10Z,13Z,16Z)-3- lysine within xylitol a (2E,4E)- superpathway of pyrimidine deoxyribonucleoside salvage phosphatidate IEK_RS04700 accA complex H protein] isovalerate demethylmenaquinol-4 butanoyl-CoA phosphate (R)-lipoate α-limit dextrin 3-ethylmalate -undecadienoyl- superpathway of inosine-5'-phosphate biosynthesis I superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis I purine deoxyribonucleosides salvage SAM a sulfurated [sulfur carrier] phosphate hydroxydocosatetraenoyl-CoA gcv protein H dienoyl-CoA uridine kinase: cytidylyltransferase: 6 NAD(P)- glycogen/starch/ guanosine nucleotides acetyl-CoA carboxylase N -octanoyl-L-lysine acetate--CoA ligase: orotate demethylmenaquinone phosphate acetoacetyl- lipoate--protein 3-isopropylmalate CoA 2,4-dienoyl- cytidine adenosine nucleotides IEK_RS08625 acetyl-CoA Amine and Polyamine Degradation lipoyl dependent alcohol alpha-glucan 2,4-dienoyl- IEK_RS05720 de novo biosynthesis I 2'-deoxycytidine UDP CTP carboxyltransferase IEK_RS04380 phosphoribosyltransferase: methyltransferase: butyryltransferase: CoA reductase: ligase A: dehydrogenase: CoA reductase: AIR de novo biosynthesis I synthase: lipA dehydrogenase: phosphorylase: CoA reductase: [+ 2 isozymes] nucleoside a (2E)-hexadec- a CDP- subunit alpha: a [glycine-cleavage IEK_RS08320 IEK_RS06875 IEK_RS21505 cytidine 5-(carboxyamino) 2'-deoxyguanosine 2'-deoxyadenosine an unsulfurated IEK_RS19450 IEK_RS20455 a [glycine-cleavage leuB IEK_RS07755 IEK_RS07755 cytidine 2'-deoxycytidine triphosphatase diacylglycerol IEK_RS11735 4-aminobutanoate 5'-deoxyadenosine met complex H protein] isovaleryl-CoA AMP diphosphate butanoyl IEK_RS25735 IEK_RS03370 UMP deaminase: IMP imidazole ribonucleotide asp IMP deoxynucleoside deoxynucleoside 2-enoyl-[acp] 4-aminobutanoate N-acetylglucosamine [sulfur carrier] orotate PRPP (7Z,10Z,13Z,16Z)-3- complex H protein] α-D-glucopyranose (3E)-undec- a (3E)-3- deaminase: kinase: dUDP YtkD: ytkD malonyl-CoA degradation I N 6 -lipoyl-L-lysine menaquinol-4 phosphate D-xylopyranose 2-oxovalerate kinase: kinase: CDP-diacylglycerol-- degradation III oxodocosatetraenoyl-CoA N 6 -lipoyl-L-lysine enoyl-CoA IEK_RS17965 CMP synthase: IEK_RS25140 adenylosuccinate CDP palmitoyl-[acyl- degradation I 1-phosphate 3-enoyl-CoA IMP IEK_RS17965 IEK_RS00310 nucleoside-diphosphate IEK_RS00310 IEK_RS00310 glycerol-3-phosphate 3- cytidine N5-CAIR synthase: carrier-protein] [acyl-carrier-protein] S- 4-aminobutanoate N-acetyl-D- (d)CMP kinase: dehydrogenase: cytidine 5-aminoimidazole ribonucleotide biosynthesis I kinase: IEK_RS19440 deoxynucleoside phosphatidyltransferase: 4-aminobutanoate deaminase: IEK_RS00505 deoxynucleoside reductase: malonyltransferase: fabD 4-aminobutyrate- glucosamine IEK_RS19530 IEK_RS00345 deaminase: dCMP pgsA a peptide with IEK_RS06105 5-(carboxyamino)imidazole adenylo-succinate dUTP kinase: kinase: IEK_RS20945 4-aminobutyrate- a dimer of adjacent 2'- ν a peptidoglycan a lipid II 3-[(7'-methylsulfanyl) a [protein]-L- 1-(3-sn- -2-oxoglutarate 6-phosphateN-acetylglucosamine- urea h a ribonucleic acid DMKH2-13 an N-terminal ethanol CDP IEK_RS06105 (d)CMP kinase: ribonucleotide mutase: purE PRPP IEK_RS00305 IEK_RS00305 -2-oxoglutarate a (5Z)-tetradec-5-enoyl-[acp] a malonyl-[acp] ATP deoxycytidines in DNA pimeloyl-CoA ala heptyl]malate proline (ω = 180) thr dUTP diphosphatase: dCDP phosphatidyl) transaminase: 6-phosphate degradation II ammonium hydrogencarbonate peptidoglycan ribonuclease XMP IEK_RS19530 adenylosuccinate dGMP dAMP a malonyl-[acp] transaminase: deoxyribodipyrimidine demethylmenaquinone 3-isopropylmalate L-proline proline peptidylprolyl catalase: uridine a palmitoyl-[acp] gabT beta-ketoacyl-[acyl-carrier- transglycosylase: 8-amino-7- 2'-deoxyuridine CAIR lyase: IEK_RS25135 amidophosphoribosyltransferase: IEK_RS29005 nucleoside-diphosphate -sn-glycerol D-glucosaminedeacetylase: nagA carbamate photo-lyase: PH: L-threonine 3- gabT protein] synthase II: fabF methyltransferase: oxononanoate dehydrogenase: iminopeptidase: isomerase: prsA IEK_RS21260 dCDP nucleoside triphosphate kinase: IEK_RS19440 3-phosphate 4-aminobutyrate- urea IEK_RS11905 IEK_RS24040 IEK_RS05215 dehydrogenase: IEK_RS25110 3-oxoacyl-ACP synthase 4-aminobutyrate- 6-phosphate kinase: arcC di-trans,octa-cis IEK_RS19450 synthase: bioF leuB IEK_RS04360 [+ 3 isozymes] [+ 3 isozymes] inosine-uridine xanthosine-5'- phosphoribosylaminoimidazolesuccinocarboxamide urease: carbamoyl two adjacent 2'- a nucleoside IEK_RS23665 thymidine nucleoside- amidophosphoribosyltransferase: pyrophosphohydrolase: dCTP phosphatidylglycerophosphatase III: IEK_RS21160 -2-oxoglutarate acyl-carrier protein a (7Z)-3-oxo-hexadec-7-enoyl-[acp] a peptidoglycan a ribonucleic acid 8-amino-7- 10-(methylsulfanyl) preferring phosphate:L- AMP -2-oxoglutarate phosphate deoxycytidines in DNA -undecaprenyl diphosphate coenzyme A a peptide pro a [protein]-L- kinase: diphosphate synthase: IEK_RS25130 IEK_RS01935 IEK_RS00125 A: IEK_RS02925 transaminase: IEK_RS10390 menaquinol-13 oxononanoate ω aminoacetone acetaldehyde nucleoside glutamine transaminase: diphosphate -2-oxodecanoate proline ( = 0) IEK_RS01190 kinase: phosphoribosylaminoimidazolesuccinocarboxamide β an L-1- an acetoacetyl-[acp] IEK_RS24975 ammonium hydrolase: amido-ligase thymidine adenylate 5-phospho- - gly dUMP palmitate succinate IEK_RS24975 α-D-glucosamine IEK_RS19440 synthase: IEK_RS27730 phosphatidyl- succinate uracil (AMP-forming) [+ 2 isozymes] D-ribosylamine dGDP dADP semialdehyde uridine kinase: IEK_RS02215 kinase: thymidylate synthase: acyl-CoA semialdehyde 6-phosphate N-acetyl-D- sn-glycerol a 7,8-dihydro-8- (2R,3S)-3- 2-trans, 4-cis- IEK_RS05720 phosphoribosyltransferase: nucleoside- : IEK_RS25275 thymidine dCTP SAICAR IEK_RS25970 IEK_RS16380 NAD-dependent glucosamine- 4-dimethylaminophenylazobenzene DMK-12 (R)-glycerate MeOH inosine-uridine phosphoribosylamine- synthetase: succinate- a (7Z)-hexadec-7-enoyl-[acp] a malonyl-[acp] O-acetyl-L-serine hydrogen selenide galactosamine asp fumarate a D-tyrosyl-[tRNA Tyr ] undecadienoyl- IEK_RS01265 dUMP kinase: superpathway of pyrimidine nucleoside- nucleoside- succinate- oxoguanine in DNA isopropylmalate [+ 2 isozymes] preferring diphosphate dTMP IEK_RS09740 semialdehyde 6-phosphate DNA- 6-phosphate azoreductase: CoA GMP adenylosuccinate -glycine ligase: nucleobases salvage diphosphate diphosphate beta-ketoacyl-[acyl-carrier- cysteine synthase: N-acetylglucosamine- demethylmenaquinone L-aspartate D-aminoacyl- 3-isopropylmalate D-glycerate catalase: bifunctional pyrimidine nucleoside kinase: IEK_RS01190 ADP semialdehyde deaminase: formamidopyrimidine IEK_RS16365 2,4-dienoyl- thymidylate lyase: IEK_RS25135 IEK_RS25090 dTMP kinase: kinase: kinase: [+ 4 isozymes] dehydrogenase: 6-phosphate methyltransferase: oxidase: tRNA deacylase: dehydrogenase: dehydrogenase: IEK_RS21260 operon transcriptional hydrolase: IEK_RS19440 [+ 2 isozymes] uracil dehydrogenase: IEK_RS07425 protein] synthase II: fabF IEK_RS12850 CoA reductase: synthase: gabD glycosylase: mutM [+ 2 isozymes] IEK_RS05585 guanylate ADP IEK_RS00255 IEK_RS19440 IEK_RS19440 gabD deacetylase: nagA IEK_RS19450 IEK_RS05465 leuB IEK_RS03160 IEK_RS07755 [+ 3 isozymes] regulator/uracil IEK_RS13085 AICAR uracil palmitoyl-CoA acyl-carrier protein a (9Z)-3-oxo-octadec-9-enoyl-[acp] acetate L-selenocysteine an apurinic site 7,8-dihydro- D-galactosamine aniline N,N-dimethyl-1,4- kinase: IEK_RS16380 F6P acetate succinate 2-iminosuccinate a tRNA Tyr 4-methyl-2- phosphoribosyltransferase: reductase: GAR dTDP phosphoribosyltransferase: succinate within DNA 8-oxoguanine 6-phosphate phenylenediamine menaquinol-12 D-tyrosine hydroxypyruvate (3E)-undec- formaldehyde succinate oxopentanoate IEK_RS08375 nrdF IEK_RS01265 dGTP dATP 3-enoyl-CoA IEK_RS08275 uracil bifunctional nucleoside-diphosphate adenine and phosphoribosylglycinamide UMP phosphoribosylaminoimidazolecarboxamide kinase: IEK_RS19440 bifunctional pyrimidine GDP adenosine salvage I dADP formyltransferase: formyltransferase/IMP cyclohydrolase: purH operon transcriptional a dimer of (2E,4E)- UMP kinase: IEK_RS25100 dTTP adenine salvage 5,10-methylene- 3-methyl-2- (5Z,8Z,11Z,14Z,17Z) a dimer of adjacent (2R,3S)-3- regulator/uracil coenzyme A hν ν ammonium NAD(P) + H O DMKH2-11 O-ureido-L- (R)-glycerate prephenate -icosapentaenoate non-adjacent h 2 asp a type IV prepilin tetradeca-2,4- IEK_RS18360 FAICAR nucleoside- tetrahydromethanopterin oxobutanoate thymidines in DNA homoserine isopropylmalate guanine and dTMP adenosine FGAR phosphoribosyltransferase: Inorganic Nutrient Metabolism 3-methyl-2-oxobutanoate acyl-CoA synthetase: deoxyribodipyrimidine thymidines in DNA nitrite reductase dienoyl-CoA [+ 2 isozymes] deoxyribodipyrimidine demethylmenaquinone argininosuccinate prepilin 3-isopropylmalate D-glycerate prephenate nucleoside- GDP purine-nucleoside bifunctional diphosphate IEK_RS08275 hydroxymethyltransferase: IEK_RS17385 photo-lyase: (NAD(P)H) small 2,4-dienoyl- guanosine salvage dTMP kinase: adenine photo-lyase: methyltransferase: synthase: peptidase: dehydratase: dehydrogenase: dehydratase: UDP diphosphate reductase: phosphorylase: phosphoribosylaminoimidazolecarboxamide kinase: phosphoribosylformylglycinamidine UMP panB [+ 4 isozymes] IEK_RS11905 subunit: nirD CoA reductase: IEK_RS00255 selenate reduction IEK_RS11905 IEK_RS19450 IEK_RS04555 IEK_RS20505 leuD leuC IEK_RS03160 IEK_RS05445 kinase: nrdF formyltransferase/IMP cyclohydrolase: purH IEK_RS19440 synthase: IEK_RS25115 2-aminoethylphosphonate (5Z,8Z,11Z,14Z,17Z) two adjacent a cleaved type IEK_RS07755 nucleoside- IEK_RS07260 UMP kinase: IEK_RS18360 THMPT 2-dehydropantoate a thymidine in DNA nitrite canavaninosuccinate (2S)-2- 3-phenyl-2- guanosine IEK_RS19440 dTDP IEK_RS25120 IEK_RS25125 degradation I -icosapentaenoyl-CoA thymidines in DNA menaquinol-11 a peptide hydroxypyruvate (3E)-tetradec- purine-nucleoside [+ 2 isozymes] IV prepilin diphosphate purine-nucleoside dATP adenine adenine deaminase: selenate urea cycle isopropylmalate 3-enoyl-CoA oxopropanoate kinase: nucleoside- phosphorylase: deoD IMP FGAM (2-aminoethyl) phosphorylase: dGDP UDP phosphoribosyltransferase: IEK_RS12390 sulfate IEK_RS19440 diphosphate adenine phosphonate IEK_RS07260 GTP xanthine and nucleoside-diphosphate IEK_RS05575 adenylyltransferase: sat 2-aminoethylphosphonate- kinase: guanine and phosphoribosylformylglycinamidine adenosine 5'- arg a 1-(1-alkenyl) RNase III mRNA 2'-deoxycytidine (R)-3- UTP nucleoside- -pyruvate serotonin [DNA] purine-nucleoside IEK_RS19440 adenine xanthosine salvage cyclo-ligase: IEK_RS25105 kinase: IEK_RS19440 a [protein]-L-glutamine -sn-glycero-3- processing GSSH sulfite DMKH2-10 L-saccharopine homogentisate macrocin DHAP guanosine salvage II phosphoselenate transaminase: phnW deoxynucleoside hydroxybutanoate phosphorylase: deoD diphosphate phosphoribosyltransferase: hypoxanthine protein-glutamine gamma- phosphocholine exodeoxyribonuclease substrate rhodanese domain- dTTP UTP phosphonoacetaldehyde lysoplasmalogenase: ribonuclease III: demethylmenaquinone kinase: IEK_RS00310 3-hydroxybutyrate saccharopine homogentisate macrocin O- methylglyoxal CTP synthase: guanine kinase: IEK_RS05575 AIR AMP arginase: glutamyltransferase: containing protein: xanthosine argininosuccinate IEK_RS24465 III: xth methyltransferase: dehydrogenase: dehydrogenase: 1,2-dioxygenase: methyltransferase: synthase: IEK_RS01150 IEK_RS19440 guanosine CTP synthase: xanthine a 2'- IEK_RS08490 deoxynucleoside lyase: argH rocF phosphonoacetaldehyde IEK_RS07915 sn-glycero-3- RNase III IEK_RS18040 IEK_RS19450 IEK_RS07545 IEK_RS20400 IEK_RS25475 IEK_RS20995 IEK_RS19350 xanthine IEK_RS01150 phosphoribosyltransferase: ammonium a [protein] N 6 -[(5-hydroxy-1H a fatty aldehyde deoxyribonucleoside [DNA] kinase: IEK_RS00305 CTP synthase: AMP purine-nucleoside an mRNA fragment processing glutathione selenite argininosuccinate arginase: hydrolase: IEK_RS20410 phosphocholine 5'-monophosphate thiosulfate allysine glu 4-maleyl- IEK_RS15495 phosphoribosyltransferase: dGTP phosphorylase: deoD CTP synthase: IEK_RS19180 -indol-3-yl)ethyl]-L-glutamine product mRNA menaquinol-10 dCMP acetoacetate tylosin methylglyoxal lyase: IEK_RS10115 rocF carbamoyl- acetoacetate IEK_RS19180 purine-nucleoside IEK_RS15495 [+ 2 isozymes] phosphate acetaldehyde [+ 2 isozymes] phosphorylase: guanine L-arginino- CTP L-ornithine synthase: IEK_RS07260 IMP succinate acetaldehyde 5-amino-4- RNase R degradation α-D- UDP-4-amino-4-deoxy- a [lipoyl-carrier trans-∆ 2 , cis-∆ 4 - CDP-α-D-glucose xanthine IEK_RS08295 PRPP a sphingomyelin a single a ribonucleoside β (R)-lipoate DMKH leukotriene-D4 choline GMP xanthine dehydrogenase: glucopyranose CTP -L-arabinopyranose 2 selenodiglutathione IEK_RS08300 imidazolecarboxyamide substrate RNA stranded DNA triphosphate protein]-L-lysine decadienoyl-CoA CDP- phosphoribosyltransferase: argininosuccinate IEK_RS05765 adenine UDP-4-amino-4, 6- lipoate--protein membrane CTP xanthine sphingomyelin ribonuclease 1-phosphate DNA primase: demethylmenaquinone 2,4-dienoyl- glucose 4,6- IEK_RS19180 synthase: carbamoyl phosphoribosyltransferase: glucose-1-phosphate dideoxy-N-acetyl- ligase A: dipeptidase: choline kinase: phosphoribosyltransferase: phosphodiesterase: sph R: rnr IEK_RS06140 methyltransferase: CoA reductase: dehydratase: IEK_RS04555 acetyl-CoA cytidylyltransferase: beta-L-altrosamine IEK_RS08865 IEK_RS01585 [+ 2 isozymes] phosphate IEK_RS05575 a ceramide a nucleoside 5'- ssDNA/pppN(pN) IEK_RS21505 IEK_RS19450 IEK_RS07755 IEK_RS19180 ornithine phosphocholine a diribonucleotide rfbF transaminase: pseC a [lipoyl-carrier protein]- rfbG AICAR monophosphate hybrid α n -1 UDP-β-L-threo- 6 leukotriene-E4 gly (2E)-dec-2- CDP-4-dehydro-6- carbamoyltransferase: CDP- -D-glucose N -lipoyl-L-lysine MQH phosphocholine GMP glutathioselenol 2 XMP argF pentapyranos-4-ulose enoyl-CoA deoxy-α-D-glucose assimilatory L-citrulline sulfate activation a DNA containing β sulfate reduction III a single- 4-fumaryl- (R)-N-formyl- - 2+ (S)-2,3- HMG-CoA 2-succinylbenzoate coenzyme A protoporphyrin IX Mg formate CTP sec for sulfonation stranded RNA an apurinic/ acetoacetate met hydroxy-L-kynurenine sarcosine a tRNA ser dihydrodipicolinate cyanate degradation hydroxymethylglutaryl- o-succinylbenzoate- apyrimidinic site fumarylacetoacetase: arylformamidase: magnesium hydrogen selenide sulfate polyribonucleotide endonuclease methionine anaerobic glycine serine-- dipicolinate sulfate chelatase: nucleotidyltransferase: pnp CoA lyase: IEK_RS15045 -CoA ligase: menE IEK_RS25480 gamma-lyase: kynB ribonucleoside- oxidase tRNA ligase: synthase sulfate sulfate 4-(2'-carboxyphenyl) III: nth CO a nucleoside a single- a 3'-terminal a 5'-phospho- (R)-β-hydroxy- IEK_RS21775 triphosphate IEK_RS00325 subunit adenylyltransferase: sat 2 carbonic acetyl-CoA acetoacetate acetoacetate fumarate IEK_RS04435 formate ThiO: thiO adenylyltransferase: sat diphosphate stranded RNA -4-oxobutyryl-CoA L-kynurenine Mg- an L-seryl- anhydrase: unsaturated sugar [DNA] 2-oxobutanoate methanethiol reductase: nrdD methylamine glyoxylate B: dpaB APS protoporphyrin [tRNA sec ] IEK_RS27570 APS dCTP dipicolinate phosphoadenylyl-sulfate [+ 2 isozymes] adenylyl-sulfate reductase: IEK_RS19895 kinase: cysC a 1-O-(alk-1-enyl)-sn-glycero- a 5S rRNA D-sedoheptulose D-glyceraldehyde 7,8- D-erythrose D-xylulose UTP (2R,3S)-2- + UTP N-ethylglycine β-D-allopyranose 3-phosphate coenzyme A NADP formate L-canavanine carbamate cyanase:hydrogencarbonate 3-phosphoethanolamine precursor 7-phosphate dihydromonapterin 4-phosphate 5-phosphate nucleoside triphosphate methylisocitrate sulfite PAPS transketolase: tkt dihydroneopterin transketolase: tkt arginase: rocF glycine D-ribose cynS lysoplasmalogenase: ribonuclease CoA-disulfide pyrophosphohydrolase: methylisocitrate anaerobic transketolase: tkt aldolase: folB transketolase: tkt arginase: rocF oxidase pyranase: assimilatory sulfite IEK_RS24465 M5: rnmV reductase: cdr IEK_RS00125 lyase: prpB ribonucleoside- sn-glycero-3- a double-stranded D-xylulose D-ribose 5- 6-(hydroxymethyl) D-glyceraldehyde ThiO: thiO reductase (NADPH) thiosulfate a fatty aldehyde a mature 5S-rRNA glycolaldehyde H + NADPH CoA-disulfide F6P pyruvate succinate triphosphate urea IEK_RS23450 oligonucleotide 5-phosphate phosphate -7,8-dihydropterin 3-phosphate UMP L-canaline : IEK_RS19880 CO cyanate disproportionation phosphoethanolamine reductase: nrdD ethylamine glyoxylate 2 β-D-allofuranose IV (rhodanese) dUTP hydrogen sulfide thiosulfate rhodanese domain- phosphate containing protein: glyphosate acquisition IEK_RS18040 degradation II sulfite thiocyanate a phosphate monoester acid glyphosate phosphatase: glycine IEK_RS22670 oxidase ThiO: thiO phosphate (aminomethyl) glyoxylate phosphonate a branched- chain D-cellobiose an amino an amino an amino an amino a dicarboxylate amino acid 6'- lactose 6'-phosphate a dicarboxylate acid acid acid acid molybdate phosphate phosphate β β phosphate D-cellobiose 6'-phosphate phosphonate a - a - a branched- a branched- a branched- a carbohydrate an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino sn-glycerol sn-glycerol sn-glycerol 2+ an inorganic an inorganic D-glucose 6- D-glucose 6- a C4- a C4- phosphate phosphate glycine betaine pro glucoside 6- glucoside 6- chain chain chain lactose 6'-phosphate D-trehalose D-trehalose Co 2+ 2+ 2+ a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA (S)-lactate (S)-lactate (S)-lactate a carbohydrate a carbohydrate molybdate acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid a nucleoside phosphate ammonium a nucleoside phosphonate ferrichrome ferrichrome D-glucose D-glucose a nucleoside Mg Mg Mg an aromatic an aromatic 3-phosphate 3-phosphate 3-phosphate D-cellobiose 6'-phosphate 6-phosphate 6-phosphate 2+ cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA anion anion phosphate phosphate dicarboxylate dicarboxylate phosphate pro phosphate phosphate amino acid amino acid amino acid predicted Mg cis-vaccenoyl-CoA carboxylate carboxylate predicted predicted predicted predicted ABC predicted predicted predicted predicted predicted ABC ABC ABC ABC transporter PEP-driven PEP-driven predicted ABC predicted ABC ABC ABC ABC RS24655 RS09925 RS09980 RS19030 RS15440 RS01810 RS24370 RS10560 RS02630 RS27410 RS27750 RS23310 RS25470 RS12190 RS20055 RS12560 RS23540 RS23630 RS22655 transporter transporter transporter transporter RS23795 RS04530 RS16160 RS23260 RS24200 RS06950 RS23930 RS27540 GlpT RS24935 RS09460 RS19745 RS22810 RS23985 RS21255 RS13600 PutP RS22035 RS26780 BrnQ RS17790 RS18680 of a RS01720 RS09970 transporter transporter RS22790 RS24690 RS23620 RS05505 RS00955 RS25630 RS04100 RS17975 CorA RS19110 MgtE RS17120 RS17385 RS05070 RS22405 RS09730 RS09740 transporter of RS20830 RS01755 RS23715 RS23490 RS22395 RS07445 RS29850 RS12510 transporter of RS23920 ModA transporter transporter transporter of an of an of an of an branched- of D- of lactose/ phosphonate a carbohydrate of molybdate of phosphate of phosphate amino acid amino acid amino acid amino acid chain cellobiose D-cellobiose a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid ammonium amino acid cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate

an inorganic an inorganic a C4- a C4- glycine betaine a branched- a branched- a branched- a branched- lactose lactose Co 2+ phosphonate (S)-lactate (S)-lactate (S)-lactate D-glucose D-glucose a carbohydrate a carbohydrate a carbohydrate molybdate molybdate an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino sn-glycerol sn-glycerol sn-glycerol a nucleoside a β-glucoside a β-glucoside a nucleoside phosphonate D-cellobiose trehalose trehalose ferrichrome ferrichrome D-glucose D-glucose a nucleoside Mg 2+ Mg 2+ Mg 2+ anion anion dicarboxylate dicarboxylate an aromatic an aromatic phosphate phosphate phosphate phosphate phosphate pro pro chain chain chain chain D-cellobiose D-cellobiose Mg 2+ acid acid acid a dicarboxylatean amino acid acid acid acid acid acid acid acid a dicarboxylatean amino acid acid acid acid acid acid acid acid acid acid acid acid 3-phosphate 3-phosphate 3-phosphate phosphate acid acid carboxylate carboxylate amino acid amino acid amino acid amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.