DOCSLIB.ORG

Dietary Supplements E-Newsletter

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Dietary Supplements E-Newsletter Dietary Supplements | USP–NF | Pharmacopeial Forum | Reference Standards | Resources | USP Store November 2015 What's New Quick Links USP–NF USP–NF Online PF Online New USP GMP Facility Audit Program DS Compendium for Dietary Supplements and Ingredients! DS Development Process Use the most authoritative source for dietary supplement Key Issues GMP audits! Read more… Donor Program Chromatographic Columns Adulteration and Fraud in Contact Us Food Ingredients and Dietary Supplements— Attend Two Key Learning USP Events Reference Standards Food Fraud Mitigation Course (Dec 2, 2015) Economically Motivated Adulteration (EMA) and food counterfeiting Dietary Supplements RS are major threats to the integrity of the nation´s food supply. The Release Notification Food Safety Modernization Act (FSMA) and a new FDA rule now requires food manufacturers to develop a Food Safety Plan and mitigate foreseeable risks. USP´s timely course will introduce users USP Near to its Food Fraud Mitigation Guidance. Read more… You 4th Adulteration Workshop (Dec 3–4, 2015) This two-day workshop—co-sponsored by the American Botanical Calendar of Events Council and the Food Protection and Defense Institute—allows User Forums attendees to explore new tools to help detect fraud and EMA, hear Global Education and about factors impacting supply chain integrity, and learn about the Training validity of DNA based methods for identity. Register for Both Events and Save! USP Releases New Reference Standards Arabinose (Item # 1042055) Astragalus Root Dry Extract (Item # 1044119) Calcium Succinate (Item # 1087360) Calling For Sponsors For Chondroitin Sulfate Sodium, Shark (Item # 1133569) New USP Standards For N-Acetyl-D,L-Methionine (Item # 1009978) Probiotics Ubiquinol (Item # 1705334) • Upcoming Workshops: New Reference Standards Coming Soon Cinnamaldehyde Adulteration and Fraud in Cinnamomum cassia Twig Powder Food Ingredients and Didymin Dietary Supplements: D-Salicin Attend Two Key Learning Gallic Acid Events Hesperidin Isonaringin • Food Fraud Mitigation Lonicear macranthoides Flower Dry Extract Course (Dec 2, 2015) Lonicera japonica Flower Dry Extract • 4th Adulteration Workshop Luteolin-7-O-glucoside (Dec 3–4, 2015) Neohesperidin (Co-sponsored by: American Oleuropein Botanical Council and Food Olive Leaf Dry Extract Protection & Defense Institute) Red Clover Aerial Parts Isoflavone Aglycones Dry Extract Register for Both Events Salix spp. Bark Dry Extract and Save! Click the Register Secoxyloganin button for course and Verbascoside workshop pricing. Consult Willow Bark Dry Extract Find a Reference Standard the agenda for course Suggest a Reference Standard details and list of distinguished presenters. Monographs in Revision Bulletin (Published Sept 25, 2015. Official Nov 1, 2015) • Calcium L-5-Methyltetrahydrofolate Capsules Priority New Dietary Calcium L-5-Methyltetrahydrofolate Tablets Supplement Monographs (updated 24-Sept-2015) Monographs in PF 41(6) USP is seeking sponsors… (To be published Nov 1, 2015. Comments due by Jan 31, 2016) Read More New: Creatine • USP Dietary Salix spp. Bark ( | Dry Extract | Powder) Sodium Ferrous Citrate Supplements & Herbal Tienchi Ginseng Root and Rhizome Dry Extract (Capsules | Tablets) Medicines (DSHM) Tienchi Ginseng Root and Rhizome Powder (Capsules | Tablets) Nomenclature News Revisions: Ascorbic Acid Injection • USP Admission Histidine Evaluation of Articles Potassium Gluconate ( | Oral Solution | Tablets) Prior to Monograph Riboflavin Tablets Rutin Development Thiamine Hydrochloride Tablets Tribasic Calcium Phosphate • Expert Panel Update: <2251> Adulteration of Monographs in PF 41(5) Dietary Supplements with (Published Sept 1, 2015. Comments due by Nov 30, 2015) Drugs and Drug Analogs New: Eleuthero Root and Rhizome Dry Extract (Capsules | Tablets) Japanese Honeysuckle Flower ( | Dry Extract | Powder) Olive Leaf ( |Dry Extract | Powder) Red Clover Aerial Parts Isoflavone Aglycones Dry Extract Revisions: Ashwagandha Root Curcuminoids Eleuthero Niacin Powdered Ashwagandha Root ( | Extract) Purchase the 2015 Dietary Powdered Eleuthero ( | Extract) Supplements Powdered Red Clover Extract Compendium (DSC) Powdered St. John´s Wort Extract Powdered Turmeric ( | Extract) Schizochytrium Oil Frequently Asked Turmeric Questions (FAQ): Read about monographs slated for PF 42(1) and PF 42(2)… Q. How should the USP Reference Standards (RS) New Monographs Under Development be used properly? Artichoke Leaf ( | Dry Extract | Powder) Coffee Green Bean Extract Can a chewable tablets Cranberry Juice-Derived Powder Q. Dried Tangerine Peel product be subjected only to Elderberry Dry Extract Disintegration testing and Eleuthero Root and Rhizome Powder (Capsules | Tablets) that there would be no need Ginkgo (Capsules | Tablet) to verify the release of the Guarana Seed ( | Dry Extract | Powder) dietary ingredients via Probiotics: Bacillus Coagulans PTA-11748, Lactobacillus Acidophilus LA-14, Lactobacillus Acidophilus NCFM, Lactobacillus Rhamnosus Dissolution test? HN001, Bacillus Coagulans 5856, Lactobacillus Paracasei LPC-37 Red Clover Tablets Published by: Szechuan Lovage Gabriel Giancaspro, Ph.D. Submit Monographs and Revisions Vice President General Chapters in PF 41(5) Foods, Dietary Supplements (Published Sept 1, 2015. Comments due by Nov 30, 2015) & Herbal Medicines Revisions: Comments and questions <2040> Disintegration and Dissolution of Dietary Supplements <2750> Manufacturing Practices for Dietary Supplements Questions? General Chapters in PF 41(6) Email: [email protected] (To be published Nov 1, 2015. Comments due by Jan 31, 2016) Phone: +1-301-816-8134 Revisions: Contact Us <481> Riboflavin Assay <531> Thiamine Assay General Chapters Under Development Revisions: <91> Calcium Pantothenate Assay Copyright © 2015 United States <115> Dexpanthenol Assay Pharmacopeial Convention <171> Vitamin B12 Activities Assay Donor Recognition Program (Effective January 2016) USP has expanded its Donor Recognition Program to further recognize contributors who participate in the standards-setting process and help make an impact on global health. Visit the Donor Recognition page to learn more. .
Load more

Recommended publications
  • Commission Implementing Regulation (EU)
    21.3.2013 EN Official Journal of the European Union L 80/1 II (Non-legislative acts) REGULATIONS COMMISSION IMPLEMENTING REGULATION (EU) No 230/2013 of 14 March 2013 on the withdrawal from the market of certain feed additives belonging to the group of flavouring and appetising substances (Text with EEA relevance) THE EUROPEAN COMMISSION, submitted before that deadline for the only animal category for which those feed additives had been auth­ orised pursuant to Directive 70/524/EEC. Having regard to the Treaty on the Functioning of the European Union, (4) For transparency purposes, feed additives for which no applications for authorisation were submitted within the Having regard to Regulation (EC) No 1831/2003 of the period specified in Article 10(2) of Regulation (EC) No European Parliament and of the Council of 22 September 1831/2003 were listed in a separate part of the 2003 on additives for use in animal nutrition ( 1 ), and in Community Register of Feed Additives. particular Article 10(5) thereof, (5) Those feed additives should therefore be withdrawn from Whereas: the market as far as their use as flavouring and appetising substances is concerned, except for animal species and categories of animal species for which applications for (1) Regulation (EC) No 1831/2003 provides for the auth­ authorisation have been submitted. This measure does orisation of additives for use in animal nutrition and not interfere with the use of some of the abovemen­ for the grounds and procedures for granting such auth­ tioned additives according to other animal species or orisation. Article 10 of that Regulation provides for the categories of animal species or to other functional re-evaluation of additives authorised pursuant to Council groups for which they may be allowed.
    [Show full text]
  • Dietary Supplements: Enough Already!
    Dietary Supplements: Enough Already! Top Ten Things to Know Rhonda M. Cooper‐DeHoff, Pharm D, MS, FACC, FAHA University of Florida Associate Professor of Pharmacy and Medicine Presenter Disclosure Statement No conflicts or commercial relationships to disclose Learning Objectives After this lecture you will be able to: Understand current usage and expenditure patterns for dietary supplements Recall US regulations surrounding dietary supplements Recognize how dietary supplements may affect efficacy of and interact with prescription drugs Promote patient safety by counseling patients on issues pertaining to dietary supplement use Audience Response I take (have taken) herbal / dietary supplements Audience Response I recommend (have recommended) herbal/ dietary supplements to my patients #1 Definition and Cost of Complimentary and Alternative Medicine (CAM) Categories of CAM (NIH) •Group of diverse medical and healthcare systems, Definition practices and products that are not generally considered part of conventional medicine. Alternative Biologically Manipulative Mind‐body Energy Medical Based and Body‐ Techniques Medicine Based Systems Vitamins Approaches & Spiritual Biofield Acupunct. Minerals Massage Natural therapy Magnetic Chinese Products Meditative field Medicine •Plants (gingko) Chiropract medicine Relaxation Reiki Ayurveda Diets 1998 Expenditure on CAM Manipulative and Biologically Mind‐body Alternative Body‐Based Energy Medicine Based Techniques Medical Systems Approaches 1.5% of $34 total HCE Billion but 11% of OOP OOP NCAM 2007
    [Show full text]
  • St. John's Wort 2018
    ONLINE SERIES MONOGRAPHS The Scientific Foundation for Herbal Medicinal Products Hyperici herba St. John's Wort 2018 www.escop.com The Scientific Foundation for Herbal Medicinal Products HYPERICI HERBA St. John's Wort 2018 ESCOP Monographs were first published in loose-leaf form progressively from 1996 to 1999 as Fascicules 1-6, each of 10 monographs © ESCOP 1996, 1997, 1999 Second Edition, completely revised and expanded © ESCOP 2003 Second Edition, Supplement 2009 © ESCOP 2009 ONLINE SERIES ISBN 978-1-901964-61-5 Hyperici herba - St. John's Wort © ESCOP 2018 Published by the European Scientific Cooperative on Phytotherapy (ESCOP) Notaries House, Chapel Street, Exeter EX1 1EZ, United Kingdom www.escop.com All rights reserved Except for the purposes of private study, research, criticism or review no part of this text may be reproduced, stored in a retrieval system or transmitted, in any form or by any means, without the written permission of the publisher. Important Note: Medical knowledge is ever-changing. As new research and clinical experience broaden our knowledge, changes in treatment may be required. In their efforts to provide information on the efficacy and safety of herbal drugs and herbal preparations, presented as a substantial overview together with summaries of relevant data, the authors of the material herein have consulted comprehensive sources believed to be reliable. However, in view of the possibility of human error by the authors or publisher of the work herein, or changes in medical knowledge, neither the authors nor the publisher, nor any other party involved in the preparation of this work, warrants that the information contained herein is in every respect accurate or complete, and they are not responsible for any errors or omissions or for results obtained by the use of such information.
    [Show full text]
  • Fungal Endophytic Community Associated with Guarana (Paullinia Cupana Var. Sorbilis): Diversity Driver by Genotypes in the Centre of Origin
    Journal of Fungi Article Fungal Endophytic Community Associated with Guarana (Paullinia cupana Var. Sorbilis): Diversity Driver by Genotypes in the Centre of Origin Carla Santos 1 , Blenda Naara Santos da Silva 2,3, Ana Francisca Tibúrcia Amorim Ferreira e Ferreira 2 , Cledir Santos 3,* , Nelson Lima 1 and Jânia Lília da Silva Bentes 2 1 CEB-Centre of Biological Engineering, Micoteca da Universidade do Minho, University of Minho, 4710-057 Braga, Portugal; [email protected] (C.S.); [email protected] (N.L.) 2 Postgraduate Program in Tropical Agronomy, Federal University of Amazonas, Manaus-AM 69067-005, Brazil; [email protected] (B.N.S.d.S.); [email protected] (A.F.T.A.F.eF.); [email protected] (J.L.d.S.B.) 3 Department of Chemical Sciences and Natural Resources, BIOREN-UFRO, Universidad de La Frontera, Temuco 4811-230, Chile * Correspondence: [email protected]; Tel.: +56-452-596-726 Received: 30 June 2020; Accepted: 28 July 2020; Published: 31 July 2020 Abstract: Guarana plant is a native of the Amazon region. Due to its high amount of caffeine and tannins, the seed has medicinal and stimulating properties. The guarana industry has grown exponentially in recent years; however, little information is available about associated mycobiota, particularly endophytic fungi. The present study aimed to compare the distribution and diversity of endophytic fungi associated with the leaves and seeds of anthracnose-resistant and susceptible guarana plants produced in Maués and Manaus, Amazonas State, Brazil. A total of 7514 endophytic fungi were isolated on Potato Dextrose Agar, Sabouraud and Czapek media, and grouped into 77 morphological groups.
    [Show full text]
  • The Use and Impact of Cognitive Enhancers Among University Students: a Systematic Review
    brain sciences Systematic Review The Use and Impact of Cognitive Enhancers among University Students: A Systematic Review Safia Sharif 1 , Amira Guirguis 1,2,* , Suzanne Fergus 1,* and Fabrizio Schifano 1 1 Psychopharmacology, Substance Misuse and Novel Psychoactive Substances Research Unit, School of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK; [email protected] (S.S.); [email protected] (F.S.) 2 Institute of Life Sciences 2, Swansea University, Swansea SA2 8PP, Wales, UK * Correspondence: [email protected] (A.G.); [email protected] (S.F.) Abstract: Introduction: Cognitive enhancers (CEs), also known as “smart drugs”, “study aids” or “nootropics” are a cause of concern. Recent research studies investigated the use of CEs being taken as study aids by university students. This manuscript provides an overview of popular CEs, focusing on a range of drugs/substances (e.g., prescription CEs including amphetamine salt mixtures, methylphenidate, modafinil and piracetam; and non-prescription CEs including caffeine, cobalamin (vitamin B12), guarana, pyridoxine (vitamin B6) and vinpocetine) that have emerged as being misused. The diverted non-prescription use of these molecules and the related potential for dependence and/or addiction is being reported. It has been demonstrated that healthy students (i.e., those without any diagnosed mental disorders) are increasingly using drugs such as methylphenidate, a mixture of dextroamphetamine/amphetamine, and modafinil, for the purpose of increasing their alertness, concentration or memory. Aim: To investigate the level of knowledge, perception and impact of the use of a range of CEs within Higher Education Institutions.
    [Show full text]
  • Nomination Background: Bladderwrack (CASRN: 68917-51-1)
    SUMMARY OF DATA FOR CHEMICAL SELECTION Bladderwrack BASIS OF NOMINATION TO THE CSWG The lack of toxicity testing coupled with a strong suspicion that adverse events may occur in humans exposed to bladderwrack is brought to the attention of the CSWG. Although bladderwrack is not thought to be one of the highest volume dietary supplements, it is widely promoted, especially to women, for weight loss. Bladderwrack is a source of iodine, and it is this iodine that provides the theoretical basis for bladderwrack’s activity. If iodine levels in bladderwrack are sufficiently high to cause weight loss, however, they would also be high enough to cause a hyperthyroid condition. Although there is information in the FDA’s Adverse Event Monitoring System that raises concerns about the safety of bladderwrack, the presence of other diet aids, especially ephedra, make it difficult to ascertain the role, if any, of bladderwrack. Thus, it is recommended that special tests be conducted on pure bladderwrack to determine if the iodine concentrations present in dietary supplements provide sufficient thyroid stimulation to pose a risk to consumers. SELECTION STATUS ACTION BY CSWG: 12/12/00 Studies requested: Subacute toxicity Chemical analysis (iodine content of diet aides vs natural bladderwrack) Priority: None assigned Rationale/Remarks: Effectiveness of bladderwrack as a diet aide appears to be based, at least in part, on iodine Content Concern about the safety of dietary supplements containing bladderwrack if weight loss is caused by hyperthyroidism from excessive iodine intake Concerns regarding possible additive or synergistic toxicities from several components in diet aides containing bladderwrack Bladderwrack 68917-51-1/84696-13-9 CHEMICAL IDENTIFICATION CAS Registry Name and Number: Fucus vesiculosus - 68917-51-1 Fucus vesiculosus, ext.
    [Show full text]
  • Convergent Evolution of Caffeine in Plants by Co-Option of Exapted Ancestral Enzymes
    Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes Ruiqi Huanga, Andrew J. O’Donnella,1, Jessica J. Barbolinea, and Todd J. Barkmana,2 aDepartment of Biological Sciences, Western Michigan University, Kalamazoo, MI 49008 Edited by Ian T. Baldwin, Max Planck Institute for Chemical Ecology, Jena, Germany, and approved July 18, 2016 (received for review March 25, 2016) Convergent evolution is a process that has occurred throughout the the evolutionary gain of traits such as caffeine that are formed via tree of life, but the historical genetic and biochemical context a multistep pathway. First, although convergently co-opted genes, promoting the repeated independent origins of a trait is rarely such as XMT or CS, may evolve to encode enzymes for the same understood. The well-known stimulant caffeine, and its xanthine biosynthetic pathway, it is unknown what ancestral functions they alkaloid precursors, has evolved multiple times in flowering plant historically provided that allowed for their maintenance over mil- history for various roles in plant defense and pollination. We have lions of years of divergence. Second, it is unknown how multiple shown that convergent caffeine production, surprisingly, has protein components are evolutionarily assembled into an ordered, evolved by two previously unknown biochemical pathways in functional pathway like that for caffeine biosynthesis. Under the chocolate, citrus, and guaraná plants using either caffeine synthase- cumulative hypothesis (26), it is predicted that enzymes catalyzing or xanthine methyltransferase-like enzymes. However, the pathway earlier reactions of a pathway must evolve first; otherwise, enzymes and enzyme lineage used by any given plant species is not predict- that perform later reactions would have no substrates with which to able from phylogenetic relatedness alone.
    [Show full text]
  • Energy Drinks: Health Risks and Toxicity
    Research Energy drinks: health risks and toxicity Naren Gunja he new millennium has ush- MB BS, FACEM, Medical Abstract 1 ered in a wave of synthetic, Director and Toxicologist, Objectives: To describe the epidemiology and toxicity of caffeinated energy and Clinical Senior caffeinated high-energy 2 T drink exposures in Australia. Lecturer drinks targeted at the youth market. Design, setting and subjects: Retrospective observational study analysing data Jared A Brown Over the past 10 years, the consump- BPharm(Hons), MPH, from calls regarding energy drink exposures recorded in the database of an Senior Poisons Specialist tion of caffeinated beverages intended Australian poisons information centre over 7 years to 2010. (Research and Audit)1 to “energise” has increased signifi- Main outcome measures: Type of exposure; co-ingestants; symptoms cantly. Energy drinks were recently reported; and reported hospitalisations. 1 NSW Poisons Information shown to comprise 20% of the total Centre, The Children’s Results: Callers reported 297 exposures to energy drinks, which showed an Hospital at Westmead, convenience store beverage market, increasing annual trend from 12 in 2004 to 65 in 2010. Median age for the 217 Sydney, NSW. with “Red Bull” and “V” accounting subjects with recreational exposure was 17 years (interquartile ratio [IQR], 15–21; 2 Discipline of Emergency range, 11–60) and 57% were male. One hundred recreational users co-ingested Medicine, Sydney Medical for over 97% of sales in this multimil- 1 School, University of lion-dollar industry. Increasingly, other substances, predominantly alcohol (50) or other caffeinated products Sydney, Sydney, NSW. toxicity from caffeine overdose is (44). The number of energy drinks consumed in one session varied greatly (median, 5 units; IQR, 3–8; range, 1–80).
    [Show full text]
  • Guarana New Zealand College of General Paullinia Cupana, P
    CONTINUING PROFESSIONAL DEVELOPMENT POTION OR POISON? providing a Pacific-specific clinical training and support programme for Pacific registrars in The Royal Guarana New Zealand College of General Paullinia cupana, P. sorbilis Practitioners’ (RNZCGP’s) General Practice Education Programme (GPEP Also known as Brazilian cocoa and ‘Zoom’ 1 and 2). This programme is run in partnership with the RNZCGP and David J Woods BSC (Hons), MPharm, MPSNZ, MRPharmS, FNZHPA the Ministry of Health. Our mission is to ‘…increase Pacific workforce in primary care by establishing a work- force training network of Primary Guarana is a berry that grows in Active constituents: Initially Care training organisations’. Venezuela and the northern parts of the active ingredient was called tetra Brazil. The name ‘guarana’ comes from methyl xantine but it was later discov- At Bader Drive Healthcare (see the Guarani tribe that lives in Brazil. ered that it is actually caffeine. The www.bdhclinicaltrainingsupport. Guarana plays a very important role in guarana plant and berry has one of the co.nz) we deliver both GP services their culture and medical folklore. The highest naturally occurring levels of caf- and community health services to herb is believed to be a magical cure feine at around 7–8%, and there are also Pacific people because we believe in for a range of complaints and a way to traces of theophylline and theobromine. delivering services in a holistic and regain strength. Guarana’s biological Instead of referring to caffeine, many integrated fashion. We have 26 staff in name, Paullinia cupana, was taken from companies and websites market their total delivering services from Mangere the German medical botanist CF Paul- products using the term ‘guaranine’ and Manurewa clinics.
    [Show full text]
  • Symrise Botanicals Product List 06-2008
    BOTANICALS PRODUCT LIST June 2008 EXTRAPONE ® EXTRAPONE ® Name Botanical Name (INCI) Symrise Symrise ProductName Product# Acai Euterpe Oleracea Extrapone ® Acai 392576 Almond Prunus Amygdalus Dulcis Extrapone ® Almond 384049 Aloe Vera Aloe Barbadensis Extrapone ® Aloe Vera 209185 Aloe Vera Aloe Barbadensis Extrapone ® Aloe Vera P 615342 Apple Pyrus Malus Extrapone ® Apple 660196 Apricot Prunus Armeniaca Extrapone ® Apricot 636518 Arnica Arnica Montana Extrapone ® Arnica 611910 Avocado Persea Gratissima Extrapone ® Avocado Special 660246 Bamboo Bambusa Vulgaris Extrapone ® Bamboo P 611699 Basil Ocimum Basilicum Extrapone ® Basil 113381 Birch Betula Alba Extrapone ® Birch 660110 Camomile Chamomilla Recutita Extrapone ® Camomile 660155 Camomile Chamomilla Recutita Extrapone ® Camomile P 614932 Cardamom Elettaria Cardamomum Extrapone ® Cardamom 145838 Cedarwood Juniperus Virginiana Extrapone ® Cedarwood 627309 EXTRAPONE ® Name Botanical Name (INCI) Symrise Symrise ProductName Product# Chili Capsicum Annuum Extrapone ® Chili 227598 Cinnamon Cinnamomum Zeylanicum Extrapone ® Cinnamon 619301 Clove Eugenia Caryophyllus Extrapone ® Clove 174537 Coconut Cocos Nucifera Extrapone ® Coconut 660159 Cotton Gossypium Herbaceum Dragocotton 676583 Cream Dried Cream Extrapone ® Cream 142895 Cucumber Cucumis Sativus Extrapone ® Cucumber 660122 Dandelion Taraxacum Officinale Extrapone ® Dandelion 681279 Eucalyptus Eucalyptus Globulus Extrapone ® Eucalyptus 614857 Ginkgo Biloba Ginkgo Biloba Extrapone ® Ginkgo Biloba 680841 Ginseng Panax Ginseng Extrapone ®
    [Show full text]
  • Research Article Guarana (Paullinia Cupana) Extract Protects Caenorhabditis Elegans Models for Alzheimer Disease and Huntington
    Hindawi Oxidative Medicine and Cellular Longevity Volume 2018, Article ID 9241308, 16 pages https://doi.org/10.1155/2018/9241308 Research Article Guarana (Paullinia cupana) Extract Protects Caenorhabditis elegans Models for Alzheimer Disease and Huntington Disease through Activation of Antioxidant and Protein Degradation Pathways 1 2 1 Patrícia Ferreira Boasquívis, Giovanna Melo Martins Silva, Franciny Aparecida Paiva, 3 3 1,2,4 Rodrigo Marinho Cavalcanti, Cecília Verônica Nunez , and Riva de Paula Oliveira 1Núcleo de Pesquisa em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil 2Departamento de Biologia Celular e Genética, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil 3Laboratório de Bioprospecção e Biotecnologia, Instituto Nacional de Pesquisas da Amazônia, Manaus, AM, Brazil 4Departamento de Biodiversidade, Evolução e Meio Ambiente, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil Correspondence should be addressed to Riva de Paula Oliveira; [email protected] Received 14 February 2018; Accepted 3 May 2018; Published 4 July 2018 Academic Editor: Luciana Mosca Copyright © 2018 Patrícia Ferreira Boasquívis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Guarana (Paullinia cupana) is largely consumed in Brazil in high energy drinks and dietary supplements because of its stimulant activity on the central nervous system. Although previous studies have indicated that guarana has some protective effects in Parkinson’s (PD), Alzheimer’s (AD), and Huntington’s (HD) disease models, the underlying mechanisms are unknown. Here, we investigated the protective effects of guarana hydroalcoholic extract (GHE) in Caenorhabditis elegans models of HD and AD.
    [Show full text]
  • The Real Deal on Brain Health Supplements: GCBH Recommendations on Vitamins, Minerals, and Other Dietary Supplements Background: About GCBH and Its Work
    The Real Deal on Brain Health Supplements: GCBH Recommendations on Vitamins, Minerals, and Other Dietary Supplements Background: About GCBH and its Work The Global Council on Brain Health (GCBH) is an independent collaborative of scientists, health professionals, scholars and policy experts from around the world who are working in areas of brain health related to human cognition. The GCBH focuses on brain health relating to people’s ability to think and reason as they age, including aspects of memory, perception and judgment. The GCBH is convened by AARP with support from Age UK to offer the best possible advice about what older adults can do to maintain and improve their brain health. GCBH members gather to discuss specific lifestyle habits that may impact people’s brain health as they age, with the goal of providing evidence-based recommendations for people to consider incorporating into their lives. Many people across the globe are interested in learning that it is possible to influence their own brain health and in finding out what can be done to maintain their brain health as they age. We aim to be a trustworthy source of information, basing recommendations on current evidence supplemented by a consensus of experts from a broad array of disciplines and perspectives. Supplements and Brain Health Members of the GCBH met in Washington, D.C., to address the about dietary supplements and brain health, provides a topic of dietary supplements and brain health for people age glossary of terms used in the document and lists resources 50 and older. Throughout the discussion, experts examined the for additional information.
    [Show full text]