Plectranthus Amboinicus
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AMERICAN JOURNAL OF PHYSIOLOGY, BIOCHEMISTRY AND PHARMACOLOGY, 2020 VOL 10, NO. 2, PAGE 55–62 10.5455/ajpbp.20190928091007 REVIEW ARTICLE Open Access Plectranthus amboinicus: A review on its pharmacological and pharmacognostical studies Punet Kumar1, Sangam2, Nitin Kumar3 1Department of Pharmaceutical Chemistry, Shri Gopichand College of Pharmacy, Bagpat 250609, India 2Department of Pharmaceutical Chemistry, Faculty of Oxford College of Pharmacy, Hapur 201001, India 3Department of Pharmacognosy, Faculty of Parmarth College of Pharmacy, Hapur 201001, India ABSTRACT ARTICLE HISTORY In this review, information regarding the phytochemistry, traditional uses, medicinal uses, Received September 28, 2019 side effects, and future perspectives of Plectranthus amboinicus are given. Plectranthus Accepted January 01, 2020 amboinicus has been used in herbal medicines for the treatment of various disorders Published March 16,2020 such as asthma, flu, eczema, and cardiovascular disorders. The plant possesses medic- KEYWORDS inal properties (such as antimicrobial activity, antifungal activity, anti-inflammatory activity, antidiabetic activity, anxiolytic activity, antineoplastic, analgesic, antimalarial, Plectranthus amboinicus; antibiofilm efficacy, diuretic, wound healing activity, skincare, respiratory disorders, and phytochemicals; antineoplastic activity; antiplatelet aggregation activity) due to the presence of various important constituents antifungal activity; or secondary metabolites such as flavonoids, glycosides, phenols, tannins, and steroids, antimicrobial activity; which have been identified through various spectroscopic methods. The different parts alcoholic extract of the plant have used to prepare medicines. Due to the presence of various important constituents, this plant can be used for medicines without side effects. Introduction Plectranthus amboinicus is a well-known plant it is easy to grow and can survive a considerable which belongs to the Lamiaceae family. It is found the rainforests of Indonesia and Malaysia, and as in almost all over India. It is a medicinal plant which The herb Coleus aromaticus belongs to the fam- has been used for treatment in folkloric medicines ilyneglect, Lamiaceae it is a popular(family houseLabiatae plant) and worldwide genus Coleus [2]. (syrup). It can also be used in other diseases such as - (now known as Plectranthus). It is a big juicy peren flu, bronchitis, and epilepsy. Photochemical study succulentnial aromatic herb herb with with very 30–90 unique cm heightsmelling and leaves thick, showsLamiaceae that it containsis a family flavonoids which containssuch as apigenin, approx- thatfleshy are leaves aromatic. and stem. This Thisplant is is a foundhighly inbranched, all over imatelyluteolin, 200and salvigeningenera and [1]. species in the 3200 with a history of treatment in diseases and use in food. taste and aroma; the leaves of this plant are ideal The botanical name of this herb Plectranthus India, and it is also cultivated in gardens due to amboinicus helps us to identify its taxonomic place. of the dishes and is also useful to cover bad odor amboinicus - for flavoring meat and fish, as it increases the taste In this case, refers to Ambon, a moun [3,4]. There is a considerable scope for research on throughouttainous, fertile the islandEast Indies located and in Africa the Maluku and was Islands even- itsDistribution applications in the food industry [5,6]. near Indonesia. From there, the plant propagated Plectranthus amboinicus is cultivated throughout who named this herb as “oregano de la Hoja Ancha.” Cubantually naturalized oregano can in stillLatin be America found growing by the Spanish, wild in India and in Malaysia. It is also found growing in Contact Punet Kumar [email protected] Assistantvarious Professor, Asian Department and American of Pharmaceutical countries, Chemistry, and it can Shri Gopichand College of Pharmacy, Bagpat 250609, India. © 2020 The Authors. This is an open access article under the terms of the Creative Commons Attribution NonCommercial ShareAlike 4.0 (https://creativecommons.org/licenses/by-nc-sa/4.0/). Punet Kumar, Sangam, Nitin Kumar Kannada: Hindi: Doddapatre, doddapatre soppu English: Patta ajavayin, Patharchur, IndianAmroda, mint pathercheer Bengali: AmalkuchiCountry borage, Indian borage, Malayalam: Gujarati: Marathi: Panikoorka Sanskrit: Ovapan Pan ova Figure 1. Plectranthus amboinicus plant. Marathi: Karpuravalli, Sugandhavalakam, Parnayavani also be grown in gardens. This plant is widely cul- Coleus aromaticusPathurchur is very [10] popular drug in India tivated and naturalized in the old and new world this herb is used in the treatment of ulcers. It is a - which is also called as oregano. In some countries, tropics. It is also known as Cuban oregano, SpanishColeus it is very common without widespread cultivation. amboinicusthyme, Orégano BrujoC. aromaticus (Puerto Rico), Indian bor kind of big juicy herb and has aromatic smell, and age, Mexican thyme, or Mexican mint (syn. of mint and also they are thick and juicy. Different Plant morphology Lour., Benth) [7,8]. kindsWhen crushedof phytochemicals or squeezed, are the present leaves givein differsmell- Herbs are perennial aged 3–10 years old and areent partsfound ofto the have plant an suchimportant as fruits, role flower in the stems,treat- highly fragrant. This plant can climb, or progress, mentleaves, of and diabetes. roots Coleus[10]. Few aromaticus nutrients is ableof this to lowerplant and can reach about 1-m height, and the leaves are - thethick, leaves simple, is broadly and light oval blade, or triangular a fat green shapes opposite (cut- betic agent and also helps in other problems caused arrangement of leaves (2.5–3 cm long). Shape of dueblood to glucose high sugar levels, levels so it such can beas usedit may as be an useful antidia in of the leaf are having crenate surfaces below which containting base numerous and apex glandularacute extensively) hairs to make[9]. Margins winter trunk: trunk has tomatoes (densely covered with terms of diabetic wound healing to heal faster, due soft short hairs). Flowers have a bell-shaped calyx to its ability to prevent, or it can decrease the risk of infectionPharmacological and complications Uses of P. amboinicus [11–13]. This herb has a traditional history. From many fourand thenarrow throat teeth. is smooth The corolla inside is withpale purplishtwo lips, andthe upper lip being ovate and thin, the lower lip having medicines. This plant is effective in wound healing years, this golden herb is very effective in folkloric five times longer than the calyx, with a short tube, impressive in this sense. The fatal toxic dose of this Classification inflated throat, and short lips [10]. particularwith very herbless wasside testedeffects, in solaboratory this herb mice is prettywhich Division: Magnoliophyta showed that the plant P. amboinicus is a herb which Kingdom: Plantae has no side effects or we can say that this amazing Clade: Angiosperms Class: Magnoliopsida Plectranthus amboinicus is a herb which is used Order: Lamiales inherb the have treatment no side of effects famous [14,15]. diseases such as cephal- Family: Lamiaceae - Genus: Plectranthus Species: Coleus aromaticus gia, otalgia, anorexia, dyspepsia bloating, colic, diar Synonyms: Coleus amboinicus Lour rhea, cholera, gums, seizures, asthma, cough, chronic cornerbronchitis, cracks kidney are treatedcalculi, vesiclewith this calculi, plant hiccough, in Jawa. Common names of Plectranthus amboinicus . [11] Plectranthusstrangury, hepatopathy, amboinicus fever,shows and anthelmintic malaria. Mouth activ- This plant is commonly known by different names ity which is already reported and it is cultivated at different places: widely because of this reason. To accommodate the 56 A J Physiol Biochem Pharmacol • 2020 • Vol 10 • Issue 2 A review on Plectranthus amboinicus research and analysis have been conducted which inside the body is also caused by metamorphism willincrease to prove in demand the antioxidant for herbal activity medicines, of P. constantamboin- processinflammation of tissue and arthritis. proteins. Autoantigen Agents that production prevent icus denaturation variables are worthwhile to develop - [16]. ornamentals.Members of Ayurvedic the genus practitionersColeus are very have import used as anti-inflammatory drugs. By doing a comparison- theant Coleusbecause varieties they provide in chronic food, cough medicine, and asthma and teinof reference denaturation. standard When drug compared and the withplant standard extract, we can find the concentration that inhibits the proP. amboinicus - includes calculus, gonorrhea, heart disease, fever, mationdrug, the at effectsdifferent were concentrations more effective. using Extracts egg albu of - piles, Dyspepsia. Since ancient times, the plant was- min. The acetaminophen were used to isstudy used the as aeffect standard of inflam drug. also widely studied for activities, such as previous alsobiochemical they are antimutagenic a good source and for cancer, the treatment these com of ponents are antigen toxic in characteristics, and Depending on the potency of extract, an inhibition preventsof proteins in vitrovaries. denaturation. After the study, Effects we are found due to that the Antimicrobial activity diseases [17]. presenceplant extract of polyphenolic shows anti-inflammatory content and may activity be due as to it The essential oil was isolated by hydrodistillation the synergistic activity of more than one compound of P.