IAEA TECDOC SERIES Integrated Integrated of Mechanical Components for Fusion to Safety Classification Approach Applications
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IPC Accessibility Guide
2 TABLE OF CONTENTS FIGURES AND TABLES ................................................................................................................. 8 Foreword ........................................................................................................................................... 10 Introduction ................................................................................................................................. 10 Evolving content ......................................................................................................................... 10 Disclosure ...................................................................................................................................... 11 Structure and content of the IPC Accessibility Guide ...................................................... 11 Content ........................................................................................................................................... 11 Executive summary ......................................................................................................................... 12 Aim and purpose of the Guide ................................................................................................ 12 Key objectives of the Guide ..................................................................................................... 12 Target audience of the Guide ................................................................................................. 12 1 General information -
ATTACHMENT 5 Lrgo-C960965-00-V
ATTACHMENT5 4. SHOCIqVIBRATION, AND ACOUSTICSANALYSIS 5. DESIGN GOALS/REQUIREMENTS vtHg-2-0!'5 REV. O SPECIfICATIONS TITLE DOCUMENTNO. REV. EquipmentSpecif cations Main RoughingPurnp Carts v049-2-001 Main TurbomolecularPump Cans v049-2-002 4 Auxiliary TurbomolecularPump Cans v049-2-003 Ion Pumps v049-2-004 2 ll2 and 122cm GateValves v049-2-005 J 10" and 14" GateValves v049-2-006 I VacuumGauges v049-2-007 0 BakeoutBlanlet System v049-2-009 I PortableSoft Wall CleanRooms vM9-2-010 0 CleanAir Supplies v049-2-011 I LN: Dewars v049-2-013 1 VacuumJack*ed Piping v049-2-016 PI BellowsExpansion Joints v049-2-017 I AmbientAir Vaporizers v049-2-055 0 80K PumpRegaroation Heater v049-2-056 0 SmallVacuum Valves v&9-2-059 0 CleanQh Tum Valves v049-2-050 0 CryogenicControl Valves v049-2-062 0 BakeoutCart v049-2-068 2 LrGO-C960965-00-v TITLE DOCUMENTNO. REV. Instrument& Control Specifications InstrumentList v049-l -036 0 E&lConstructionWork v049-2-022 0 PersonalComputers v049-2-049 0 BakeoutSystem Thermocouple v049-2-050 I MeasurementSystem T/C MeasurementPLC Interface v049-2-051 0 BakeoutPLC-TCInterface Soft ware v049-2-053 1 Functionality BakeoutSystem PC-PlC Interface v049-2-057 0 BakeoutSystem PC InterfaceSoftware v049-2-058 0 PitotTubes v049-2-079 0 DifferentialPressure Transmitlers v049-2-088 0 LevelTransmitters v049-2-089 0 PressureTransmitters v049-2-090 0 TemperatureElements v049-2-091 0 Interlocks,Permissives and Software AIarms v049-2-092 0 Material Specifications O-fungs v049-2-045 0 StainlessSteel Vessel Plate v049-2-041 1 StainlessSteel Flange Forgings v049-2-040 4 StainlessSteel Vessel Heads v049-2-039 3 LIGO VACUUM EQUIPMENT FINAL DESIGNREPORT CDRL 03 VOLUME TABLE OF CONTENT VOLUME TITLE VolumeI Project ManagementPlan VolumeII Design VolumeII AuachmentI Calculations VolumeII Attachment2 Calculations VolumeII Attachment3 Calculations Volumell Attachment4 Calculations VolumeII Attachment5 Specifications/Ir,lisc. -
Federal Hansard Acronyms List Remember: Ctrl+F for Quick Searches
Federal Hansard Acronyms List Remember: Ctrl+F for quick searches A B C D E F G H I J K L M N O P Q R S T U V W X Y Z A 2.5G [the first packet overlays on 2G networks] 2G second generation [the first generation of digital cellular networks, as opposed to analog] 3G third generation [next generation of cellular networks] 3GPP 3G Partnership Project [global standards body to oversee 3G] 4D meat from dead, dying, diseased or disabled animals 4GL fourth-generation language [computers] A&C automation and control A&D admission and disposition; alcohol and drugs A&E accident and emergency A&RMC formerly Austin & Repatriation Medical Centre [now Austin Health] AA anti-aircraft; Alcoholics Anonymous; Athletics Australia AAA Agriculture Advancing Australia; Australian Automobile Association; Australian Archaeological Association; Australian Airports Association AAAA Aerial Agricultural Association of Australia AAAE Australian Association of Automotive Electricians AAAGP Australian Association of Academic General Practice AAALAC Association for the Assessment and Accreditation of Laboratory Animal Care International AAB Australian Associated Brewers AAC Aboriginal advisory committee; Australian Arabic Council; AARNet Advisory Committee AACAP ATSIC-Army Community Assistance Program AACC Aboriginal Affairs Coordinating Committee [WA]; Australian Association of Career Counsellors AACM Australian Association for Computational Mechanics AACS Australian Associations of Christian Schools [note: Associations—plural] AACV Australian Association of Cattle Veterinarians AAD Australian Antarctic Division [Department of the Environment and Heritage] AADCP ASEAN-Australia Development Cooperation Program [taking over AAECP] AADS advanced air defence simulator AADT average annual daily traffic AaE Australian air Express Pty Ltd AAEC Antarctic Animal Ethics Committee AAECP ASEAN-Australia Economic Cooperation Program [finishes in 2005] AAFCANS Army and Air Force Canteen Service [now known as Frontline Defence Services] AAGP Australian Association of Group Psychotherapists Inc. -
EORTC QLQ-C30 Scoring Manual
All rights reserved. No part of this manual covered by copyrights hereon may be reproduced or transmitted in any form or by any means without prior permission of the copyright holder. The EORTC QLQ-C30 (in all versions), and the modules which supplement it, are copyrighted and may not be used without prior written consent of the EORTC Data Center. Requests for permission to use the EORTC QLQ-C30 and the modules, or to reproduce or quote materials contained in this manual, should be addressed to: QL Coordinator Quality of Life Unit, EORTC Data Center, Avenue E Mounier 83 - B11, 1200 Brussels, BELGIUM Tel: +32 2 774 1611 Fax: +32 2 779 4568 Email: [email protected] Copyright © 1995, 1999, 2001 EORTC, Brussels. D/2001/6136/001 ISBN 2-9300 64-22-6 Third edition, 2001 EORTC QLQ-C30 Scoring Manual The EORTC QLQ-C30 Introduction The EORTC quality of life questionnaire (QLQ) is an integrated system for assessing the health- related quality of life (QoL) of cancer patients participating in international clinical trials. The core questionnaire, the QLQ-C30, is the product of more than a decade of collaborative research. Following its general release in 1993, the QLQ-C30 has been used in a wide range of cancer clinical trials, by a large number of research groups; it has additionally been used in various other, non-trial studies. This manual contains scoring procedures for the QLQ-C30 versions 1.0, (+3), 2.0 and 3.0; it also contains summary information about supplementary modules. All publications relating to the QLQ should use the scoring procedures described in this manual. -
Latent Class Analysis to Classify Patients with Transthyretin Amyloidosis by Signs and Symptoms
Neurol Ther DOI 10.1007/s40120-015-0028-y ORIGINAL RESEARCH Latent Class Analysis to Classify Patients with Transthyretin Amyloidosis by Signs and Symptoms Jose Alvir . Michelle Stewart . Isabel Conceic¸a˜o To view enhanced content go to www.neurologytherapy-open.com Received: February 21, 2015 Ó The Author(s) 2015. This article is published with open access at Springerlink.com ABSTRACT status measures for the latent classes were examined. Introduction: The aim of this study was to Results: A four-class latent class solution was develop an empirical approach to classifying thebestfitforthedata.Thelatentclasseswere patients with transthyretin amyloidosis (ATTR) characterized by the predominant symptoms based on clinical signs and symptoms. as severe neuropathy/severe autonomic, Methods: Data from 971 symptomatic subjects moderate to severe neuropathy/low to enrolled in the Transthyretin Amyloidosis moderate autonomic involvement, severe Outcomes Survey were analyzed using a latent cardiac, and moderate to severe neuropathy. class analysis approach. Differences in health Incorporating disease duration improved the model fit. It was found that measures of health Electronic supplementary material The online status varied by latent class in interpretable version of this article (doi:10.1007/s40120-015-0028-y) contains supplementary material, which is available to patterns. authorized users. Conclusion: This latent class analysis approach On behalf of the THAOS Investigators. offered promise in categorizing patients with ATTR across the spectrum of disease. The four- Trial registration: ClinicalTrials.gov number, class latent class solution included disease NCT00628745. duration and enabled better detection of J. Alvir (&) heterogeneity within and across genotypes Statistical Center for Outcomes, Real-World and than previous approaches, which have tended Aggregate Data, Global Medicines Development, Global Innovative Pharma Business, Pfizer, Inc., to classify patients a priori into neuropathic, New York, NY, USA cardiac, and mixed groups. -
Asphalt Pavement Crack Detection and Classification Using Deep
Asphalt pavement crack detection and classification using deep Convolutional Neural Networks A Dissertation Presented to The Academic Faculty by Akshata Arvind Desai In Partial Fulfillment of the Requirements for the Degree Master of Science in the School of Electrical and Computer Engineering Georgia Institute of Technology August 2020 Copyright © 2020 by Akshata Arvind Desai Asphalt pavement crack detection and classification using deep Convolutional Neural Networks Approved by: Dr.Yi-Chang (James) Tsai, Advisor School of Civil and Environmental Engineering Georgia Institute of Technology Dr. Anthony Joseph Yezzi School of Electrical and Computer Engineering Georgia Institute of Technology Date Approved: [May 14, 2020] ACKNOWLEDGEMENTS I would like to thank my advisor, Dr. Yi-Chang (James) Tsai for providing invaluable guidance throughout my thesis research. I am extremely grateful for his time and effort in providing crucial feedback through this journey. I would also like to thank my co-advisor Dr. Anthony Joseph Yezzi for agreeing to be on the thesis committee. I would also like to thank my team for helping me all along this research. I am grateful for their time and advice. I express my thanks to Yung-An Hsieh, Lucas Yu and Zhongyu Yang. I am extremely grateful to all my other colleagues who have been helpful in one way or another. iii TABLE OF CONTENTS ACKNOWLEDGEMENTS…………………………………………………………………… iii LIST OF TABLES…………………………………………………………………………...... vi LIST OF FIGURES…………………………………………………………………………… vii SUMMARY…………………………………………………………………………………..... ix CHAPTER 1 Introduction………………………………………………………………… 1 1.1 Proposal Organization………………………………………………………………….. 2 CHAPTER 2 Literature Review………………………………………………………….. 3 2.1 Pavement Condition Evaluation Practices – Crack Type Classification…………... 3 2.1.1 Crack Properties………………………………………………………………… 7 2.2 Review of Automatic Crack Classification Methods…………………………………. -
The HHS-HCC Risk Adjustment Model for Individual and Small Group Markets Under the Affordable Care Act John Kautter,1 Gregory C
2014: Volume 4, Number 3 A publication of the Centers for Medicare & Medicaid Services, Office of Information Products & Data Analytics The HHS-HCC Risk Adjustment Model for Individual and Small Group Markets under the Affordable Care Act John Kautter,1 Gregory C. Pope,1 Melvin Ingber,1 Sara Freeman,1 Lindsey Patterson,1 Michael Cohen,2 and Patricia Keenan2 1RTI International 2Centers for Medicare & Medicaid Services Abstract: Beginning in 2014, individuals and HHS-HCC diagnostic classification, which is the small businesses are able to purchase private health key element of the risk adjustment model. Then insurance through competitive Marketplaces. The the data and methods, results, and evaluation of Affordable Care Act (ACA) provides for a program the risk adjustment model are presented. Fifteen of risk adjustment in the individual and small group separate models are developed. For each age group markets in 2014 as Marketplaces are implemented (adult, child, and infant), a model is developed for and new market reforms take effect. The purpose each cost sharing level (platinum, gold, silver, and of risk adjustment is to lessen or eliminate the bronze metal levels, as well as catastrophic plans). influence of risk selection on the premiums that Evaluation of the risk adjustment models shows plans charge. The risk adjustment methodology good predictive accuracy, both for individuals and includes the risk adjustment model and the risk for groups. Lastly, this article provides examples transfer formula. of how the model output is used to calculate risk This article is the second of three in this scores, which are an input into the risk transfer issue of the Review that describe the Department formula. -
Annona Coriacea Mart. Fractions Promote Cell Cycle Arrest and Inhibit Autophagic Flux in Human Cervical Cancer Cell Lines
molecules Article Annona coriacea Mart. Fractions Promote Cell Cycle Arrest and Inhibit Autophagic Flux in Human Cervical Cancer Cell Lines Izabela N. Faria Gomes 1,2, Renato J. Silva-Oliveira 2 , Viviane A. Oliveira Silva 2 , Marcela N. Rosa 2, Patrik S. Vital 1 , Maria Cristina S. Barbosa 3,Fábio Vieira dos Santos 3 , João Gabriel M. Junqueira 4, Vanessa G. P. Severino 4 , Bruno G Oliveira 5, Wanderson Romão 5, Rui Manuel Reis 2,6,7,* and Rosy Iara Maciel de Azambuja Ribeiro 1,* 1 Experimental Pathology Laboratory, Federal University of São João del Rei—CCO/UFSJ, Divinópolis 35501-296, Brazil; [email protected] (I.N.F.G.); [email protected] (P.S.V.) 2 Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, Brazil; [email protected] (R.J.S.-O.); [email protected] (V.A.O.S.); [email protected] (M.N.R.) 3 Laboratory of Cell Biology and Mutagenesis, Federal University of São João del Rei—CCO/UFSJ, Divinópolis 35501-296, Brazil; [email protected] (M.C.S.B.); [email protected] (F.V.d.S.) 4 Special Academic Unit of Physics and Chemistry, Federal University of Goiás, Catalão 75704-020, Brazil; [email protected] (J.G.M.J.); [email protected] (V.G.P.S.) 5 Petroleomic and forensic chemistry laboratory, Department of Chemistry, Federal Institute of Espirito Santo, Vitória, ES 29075-910, Brazil; [email protected] (B.G.O.); [email protected] (W.R.) 6 Life and Health Sciences Research Institute (ICVS), Medical School, University of Minho, 4710-057 Braga, Portugal 7 3ICVS/3B’s-PT Government Associate Laboratory, 4710-057 Braga, Portugal * Correspondence: [email protected] (R.M.R.); [email protected] (R.I.M.d.A.R.); Tel.: +55-173-321-6600 (R.M.R.); +55-3736-904-484 or +55-3799-1619-155 (R.I.M.d.A.R.) Received: 25 September 2019; Accepted: 29 October 2019; Published: 1 November 2019 Abstract: Plant-based compounds are an option to explore and perhaps overcome the limitations of current antitumor treatments. -
DNV Classification Note 31.2 Strength Analysis of Hull Structure in Roll
CLASSIFICATION NOTES No. 31.2 STRENGTH ANALYSIS OF HULL STRUCTURE IN ROLL ON/ROLL OFF SHIPS AND CAR CARRIERS APRIL 2011 The content of this service document is the subject of intellectual property rights reserved by Det Norske Veritas AS (DNV). The user accepts that it is prohibited by anyone else but DNV and/or its licensees to offer and/or perform classification, certification and/or verification services, including the issuance of certificates and/or declarations of conformity, wholly or partly, on the basis of and/or pursuant to this document whether free of charge or chargeable, without DNV's prior written consent. DNV is not responsible for the consequences arising from any use of this document by others. DET NORSKE VERITAS Veritasveien 1, NO-1322 Høvik, Norway Tel.: +47 67 57 99 00 Fax: +47 67 57 99 11 FOREWORD DET NORSKE VERITAS (DNV) is an autonomous and independent foundation with the objectives of safeguarding life, property and the environment, at sea and onshore. DNV undertakes classification, certification, and other verification and consultancy services relating to quality of ships, offshore units and installations, and onshore industries worldwide, and carries out research in relation to these functions. Classification Notes Classification Notes are publications that give practical information on classification of ships and other objects. Examples of design solutions, calculation methods, specifications of test procedures, as well as acceptable repair methods for some components are given as interpretations of the more general rule requirements. All publications may be downloaded from the Society’s Web site http://www.dnv.com/. The Society reserves the exclusive right to interpret, decide equivalence or make exemptions to this Classification Note. -
Federal Register/Vol. 65, No. 69/Monday, April 10, 2000
19188 Federal Register / Vol. 65, No. 69 / Monday, April 10, 2000 / Proposed Rules DEPARTMENT OF HEALTH AND timely will be available for public 3. Payment ProvisionsÐFacility-Specific HUMAN SERVICES inspection as they are received, Rate generally beginning approximately 3 II. Update of Payment Rates Under the Health Care Financing Administration weeks after publication of a document, Prospective Payment System for Skilled Nursing Facilities in Room 443±G of the Department's A. Federal Prospective Payment System 42 CFR Parts 411 and 489 office at 200 Independence Avenue, 1. Cost and Services covered by the Federal SW., Washington, DC, on Monday [HCFA±1112±P] Rates through Friday of each week from 8:30 2. Methodology Used for the Calculation of RIN 0938±AJ93 to 5 p.m. (phone: (202) 690±7061). the Federal Rates FOR FURTHER INFORMATION CONTACT: B. Case-Mix Adjustment and Options C. Wage Index Adjustment to Federal Rates Medicare Program; Prospective Dana Burley, (410) 786±4547 or Sheila Payment System and Consolidated D. Updates to the Federal Rates Lambowitz, (410) 786±7605 (for E. Relationship of RUG±III Classification Billing for Skilled Nursing FacilitiesÐ information related to the case-mix Update System to Existing Skilled Nursing classification methodology). Facility Level-of-Care Criteria AGENCY: Health Care Financing John Davis, (410) 786±0008 (for III. Three-Year Transition Period Administration (HCFA), HHS. information related to the Wage IV. The Skilled Nursing Facility Market Index). Basket Index ACTION: Notice of proposed rulemaking. Bill Ullman, (410) 786±5667 (for A. Facility-Specific Rate Update Factor information related to consolidated B. Federal Rate Update Factor SUMMARY: This proposed rule sets forth V. -
Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids
Published OnlineFirst July 12, 2019; DOI: 10.1158/0008-5472.CAN-19-0214 Cancer Genome and Epigenome Research Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids Saurabh V. Laddha1, Edaise M. da Silva2, Kenneth Robzyk2, Brian R. Untch3, Hua Ke1, Natasha Rekhtman2, John T. Poirier4, William D. Travis2, Laura H. Tang2, and Chang S. Chan1,5 Abstract Lung carcinoids (LC) are rare and slow growing primary predominately found at peripheral and endobronchial lung, lung neuroendocrine tumors. We performed targeted exome respectively. The LC3 subtype was diagnosed at a younger age sequencing, mRNA sequencing, and DNA methylation array than LC1 and LC2 subtypes. IHC staining of two biomarkers, analysis on macro-dissected LCs. Recurrent mutations were ASCL1 and S100, sufficiently stratified the three subtypes. enriched for genes involved in covalent histone modification/ This molecular classification of LCs into three subtypes may chromatin remodeling (34.5%; MEN1, ARID1A, KMT2C, and facilitate understanding of their molecular mechanisms and KMT2A) as well as DNA repair (17.2%) pathways. Unsuper- improve diagnosis and clinical management. vised clustering and principle component analysis on gene expression and DNA methylation profiles showed three robust Significance: Integrative genomic analysis of lung carcinoids molecular subtypes (LC1, LC2, LC3) with distinct clinical identifies three novel molecular subtypes with distinct clinical features. MEN1 gene mutations were found to be exclusively features and provides insight into their distinctive molecular enriched in the LC2 subtype. LC1 and LC3 subtypes were signatures of tumorigenesis, diagnosis, and prognosis. Introduction of Ki67 between ACs and TCs does not enable reliable stratification between well-differentiated LCs (6, 7). -
ML19092A066.Pdf
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