Contact PD/PI: Lentz, Steven R

Table 2. Participating Faculty Members

OMB Number 0925-0001 (Rev. 8/12 Approved Through 8/31/2015) Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Abel, E. Dale, MD, Professor Mentor Internal Rotation Mentor, Director Elucidating the molecular mechanisms PhD (, Molecular & Fraternal Order of Eagles of diabetes Cellular ) Diabetes Research Center Abramoff, Michael, Professor Mentor & Visual Massive, large-scale detection and MD, PhD Sciences diagnosis of retinal disease glaucoma () Adams, Christopher, Associate Mentor Dissertation Mentor Pathogenesis and treatment of skeletal MD, PhD Professor (Molecular & muscle atrophy Biophysics, , Molecular & Cellular Biology) Allen, LeeAnn, PhD Professor Mentor Internal Medicine Dissertation Mentor, Phagocyte biology with a particular (, , Admissions Committee focus on interactions of pathogenic Molecular & Cellular Biology) bacteria with macrophages and neutrophils Amendt, Brad, PhD Professor Mentor & Biology Molecular mechanisms of human craniofacial anomalies Anderson, Mark, MD, Professor Mentor Internal Medicine Dissertation Mentor Understanding the biology behind PhD (Molecular Physiology & cardiac arrhythmias Biophysics) Anderson, Michael, Associate Mentor Molecular Physiology & Dissertation Mentor Physiological properties of the eye and PhD Professor Biophysics the pathophysiological mechanisms (Genetics, ) underlying a variety of complex eye diseases Andreasen, Nancy, Professor Mentor Imaging studies of the major psychoses MD, PhD (Neuroscience, Translational Biomedicine) Badovinac, Vladimir, Associate New Mentor Generation and manipulation of memory PhD Professor (Immunology) CD8 T cell responses Baker, Sheila, PhD Assistant New Mentor Biochemistry Cellular and molecular mechanisms of Professor (Ophthalmology & Visual membrane trafficking in Sciences, Molecular & Cellular vertebrate photoreceptors Biology)

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Bassuk, Alex, MD, Associate Mentor Rotation Mentor Basic mechanisms of normal and PhD Professor (Genetics, Neuroscience, disordered development of the nervous Molecular & Cellular Biology) system Benson, Christopher, Associate New Mentor Internal Medicine Rotation Mentor, Co- Molecular mechanisms of cardiac MD Professor (Neuroscience, Pharmacology, Director SUMR Program sensatioin Translational Biomedicine) Bishop, Gail, PhD Professor Mentor Microbiology Dissertation Mentor Analysis of molecular mechanisms of (Internal Medicine, Immunology, regulation of B lymphocyte activation Molecular & Cellular Biology, Translational Biomedicine) Boles, Blaise, PhD Assistant New Mentor Microbiology Understanding the microbial ecology of Professor humans Bonthius, Daniel, MD, Professor Mentor Pediatrics Admissions Committee, Biological mechanisms to underlying PhD (Neuroscience, Molecular & Integrating Discovery & neurological birth defects Cellular Biology) Educational Activities Committee Brenner, Charles, PhD Professor Mentor Biochemistry Dissertation Mentor, Tumor suppressor and and Head (Internal Medicine, Genetics) Biochemistry Department metabolism Head, Faculty Advisor to Seminar Committee Burnett, Andrean, PhD Assistant New Mentor Pathology Rotation Mentor Signaling pathways and oxidative stress Professor (Free Radical & Radiation in cancer progression Biology, Human Campbell, Kevin, PhD Professor Mentor Molecular Physiology & Dissertation Mentor, Molecular pathogenesis of muscular and Head Biophysics Molecular Physiology & dystrophy, molecular studies of (, Internal Medicine, Biophysics Department dystroglycan complex and voltage-gated Translational Biomedicine) Head Ca2+ channels Carter, Brent, MD Professor Mentor Internal Medicine Pulmonary fibrosis, asthma, and acute (Free Radical & Radiation lung injury Biology, Human Toxicology) Chauhan, Anil, PhD Associate New Mentor Internal Medicine Vascular inflammatory diseases: stroke Professor (Molecular & Cellular Biology) and atherosclerosis

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Chen, Songhai, PhD Associate Mentor Pharmacology G protein-dependent signaling Professor (Internal Medicine, Molecular & mechanisms of leukocyte migration and Cellular Biology) tumor metastasis Chrischilles, Betsy, Professor Mentor Epidemiology Dissertation Mentor Economic evaluation of chronic disease PhD (Translational Biomedicine) ; medication use and effects among the elderly Colgan, John, PhD Associate Mentor Internal Medicine Signal transduction pathways that Professor (Anatomy & , control of the development and function Molecular & Cellular Biology, of lymphocytes Immunology) Cornell, Robert, PhD Associate Mentor Anatomy & Cell Biology Understanding regulatory Professor (Genetics, Molecular & Cellular networks that operated during Biology, Neuroscience) embryonic development Cullen, Joseph, MD Professor Mentor Role of reactive oxygen species in (Free Radical & Radiation pancreatic cancer Biology) Davies, Brandon, PhD Assistant New Mentor Biochemistry Role of endothelial cells in Professor (Molecular & Cellular Biology) metabolism DeMali, Kris, PhD Associate Mentor Biochemistry Recruitment Committee, Molecular basis of cell adhesion and its Professor (Molecular & Cellular Biology) Integrating Discovery & regulation by signaling and cytoskeletal Educational Activities Committee, Co-Director SUMR Program Domann, Frederick, Professor Mentor Radiation Dissertation Mentor, Epigenetic mechanisms of gene PhD (Molecular & Cellular Biology, Molecular & Cellular silencing in cancer Free Radical & Radiation Biology Program Director Biology, Human Toxicology) Dupuy, Adam, PhD Associate Mentor Anatomy & Cell Biology Dissertation Mentor, Developing new mouse models of Professor (Genetics, Molecular & Cellular Admissions Committee human cancer using the Sleeping Biology) Beauty transposon system Eberl, Daniel, PhD Professor Mentor Biology Genetics PhD Program Molecular and cellular mechanisms of (Genetics, Neuroscience) Director hearing in Drosophila

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Ellermeier, Craig, PhD Associate Mentor Microbiology Admissions Committee Role of Cell envelope stress response in Professor (Genetics) B. subtilis and C. difficile Engelhardt, John, PhD Professor Mentor Anatomy & Cell Biology Rotation Mentor, Molecular/cellular biology and gene and Head (Internal Medicine, Informatics, Dissertation Mentor, of inherited and environmental Molecular & Cellular Biology, Executive Committee, diseases Free Radical & Radiation Anatomy & Cell Biology Biology) Department Head Faraci, Frank, PhD Professor Mentor Internal Medicine Role of endothelial NO synthase in (Pharmacology) cerebral circulation Fingert, John, MD, Associate New Mentor Ophthalmology & Visual Dissertation Mentor, of glaucoma and PhD Professor Sciences Admissions Committee other inherited eye diseases (Genetics, Molecular & Cellular Biology) Fisher, Rory, PhD Professor Mentor Pharmacology (Internal Siganal transduction of G protein- Medicine, Molecular & Cellular coupled receptors and RGS proteins Biology) Frank, C. Andrew, PhD Assistant New Mentor Anatomy & Cell Biology Synaptic homeostasis at the Drosophila Professor (Genetics, Molecular & Cellular neuromuscular junction Biology, Neuroscience) Fuentes, Ernesto, PhD Associate Mentor Biochemistry Rotation Mentor, Energetics and dynamics of protein- Professor (Molecular & Cellular Biology) Admissions Committee, protein interactions; NMR; signal Recruitment Committee transduction pathways in cancer Geyer, Pamela, PhD Professor Mentor Biochemistry MSTP Co-Director, Chromosome organization and gene ( & Gynecology, Rotation Mentor, expression Genetics, Molecular & Cellular Executive Committee, Biology) Integrating Discovery & Educational Activities Committee, Recruitment Committee, M1G/M2G Advisor Giangrande, Paloma, Associate Mentor Internal Medicine Admissions Committee RNA-based therapies for cancer and PhD Professor (Molecular & Cellular Biology, cardiovascular disease Free Radical & Radiation Biology)

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Goel, Apollina, PhD Assistant Mentor Radiation Oncology Chemo-radiotherapy for hematological Professor (Free Radical & Radiation malignancies; understanding and Biology, Molecular & Cellular circumventing therapy-resistance in Biology) multiple myeloma Goswami, Prabhat, Professor Mentor Radiation Oncology Intracellular redox-state in regulating the PhD (Free Radical & Radiation mammalian cell cycle and intracellular Biology, Molecular & Cellular signaling networks Biology, Human Toxicology) Green, Steven, PhD Professor Mentor Biology Signal transduction, neuronal (Molecular & Cellular Biology, programmed cell death, signal Neuroscience) transduction for neurotrophic stimuli Grobe, Justin, PhD Assistant New Mentor Pharmacology Dissertation Mentor Central mechanisms of blood pressure Professor (Molecular & Cellular Biology, and metabolic rate control Neuroscience) Grosland, Nicole, PhD Associate Mentor Biomedical Engineering Dissertation Mentor Articular joint contact mechanics; total Professor joint arthroplasty; voxel-based finite element models Grumbach, Isabella, Associate New Mentor Internal Medicine Dissertation Mentor Vascular smooth muscle and MD, PhD Professor (Molecular & Cellular Biology) endothelial biology in hypertension and vascular injury Habelhah, Hasem, Associate Mentor Pathology Role of TRAF2 phosphorylation in NF- PhD Professor (Molecular & Cellular Biology) κB activation and cancer cell resistance to apoptosis Hammond, Donna, Professor Mentor Anesthesia Dissertation Mentor, Central nervous system mechanisms of PhD (Pharmacology, Neuroscience) Executive Associate pain and analgesia Dean Harty, John, PhD Professor Mentor Microbiology Dissertation Mentor, Immunobiology of T cell responses to (Immunology) Admissions Committee pathogens Henry, Michael, PhD Associate Mentor Molecular Physiology & Dissertation Mentor Molecular and cellular biology Professor Biophysics underlying cancer metastasis Hirsch, Raphael, MD Professor Mentor Pediatrics Pediatrics Department Inflammatory mediators in arthritis and Head (Immunology) Head

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Hoffman, Eric, PhD Professor Mentor Dissertation Mentor Cardiac mechanics; quantitative (Biomedical Engineering, assessment of cardiopulmonary Internal Medicine, Informatics, physiology via dynamic, volumetric CT; Translational Biomedicine) emerging therapies for lung disease; airway reactivity Horswill, Alex, PhD Associate Mentor Microbiology Dissertation Mentor, Peptide quorum sensing system of Professor Recruitment Committee Staphylococcus aureus Houston, Douglas, Associate Mentor Biology Maternal transcription factor and PhD Professor (Genetics, Molecular & Cellular signaling pathways in vertebrate Biology, Neuroscience) development Houtman, Jon, PhD Associate Mentor Microbiology Dissertation Mentor, Role of adaptor proteins in T Cell Professor (Internal Medicine, Molecular & Recruitment Committee, activation Cellular Biology, Immunology) Executive Committee Irani, Kaikobad, MD Professor New Mentor Internal Medicine Molecular basis for vascular function (Molecular & Cellular Biology, and dysfunction and redox biology Free Radical & Radiation Biology) Janz, Siegfried, MD Professor Mentor Pathology Mouse models of human B cell and (Immunology) plasma cell neoplasms Kaboli, Peter, MD Professor Mentor Internal Medicine Dissertation Mentor services research, evaluation of (Epidemiology) medication appropriateness, prevention of adverse drug events Karandikar, Nitin, MD, Professor Mentor Pathology Executive Committee, Immune interactions underlying the PhD and Head (Immunology, Molecular & Pathology Department pathogenesis and regulation of immune- Cellular Biology) Head based diseases Kirby, John, PhD Professor Mentor Microbiology Signal transduction in bacteria (Genetics, Informatics) Kitamoto, Toshihiro, Associate Mentor Anesthesia Genetics of complex behavior PhD Professor (Neurology, Pharmacology, Genetics, Neuroscience)

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Klingelhutz, Al, PhD Associate Mentor Microbiology Mechanisms of cellular immortalization Professor (Genetics, Informatics, and transformation by human Molecular & Cellular Biology, papillomavirus Free Radical & Radiation Biology) Kohen, Amnon, PhD Professor Mentor Chemistry Dissertation Mentor, Chemical catalysis with biological (Molecular & Cellular Biology) Admissions Committee systems (enzymes), using tools of organic and physical chemistry Kwitek, Anne, PhD Associate Mentor Pharmacology Genetics of hypertension, diabetes and Professor (Internal Medicine, Genetics) obesity using both animal models and human populations Lee, Amy, PhD Associate Mentor Molecular Physiology & Rotation Mentor, Voltage gated Ca2+ channels Professor Biophysics Assistant Dean Scientific (Otolaryngology-Head & Neck Affairs Surgery, Neuroscience) Lee, Gloria, PhD Professor Mentor Internal Medicine Dissertation Mentor Structure and function of the neuronal (Molecular & Cellular Biology, cytoskeleton and its role in Neuroscience) neurodegenerative diseases Legge, Kevin, PhD Associate Mentor Pathology Rotation Mentor Dendritic Cell Immunobiology and Professor (Microbiology, Immunology) Pulmonary Immunity Lehmler, Hans- Associate Mentor Occupational & Environmental Disposition and metabolism of chiral Joachim, PhD Professor Health environmental contaminants (Human Toxicology) Lentz, Steven, MD, Professor Mentor Internal Medicine MSTP Director, Mechanisms of thrombosis and vascular PhD (Biomedical Engineering, Dissertation Mentor, disease Molecular & Cellular Biology, Executive Committee, Translational Biomedicine) Integrating Discovery & Educational Activities Committee, M6G Advisor Leslie, Kimberly, MD Professor Mentor Obstetrics & Gynecology Obstetrics & Gynecology of hormone action and Head (Molecular & Cellular Biology) Department Head and hormone receptors in reproductive tissues

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Lin, Fang, MD, PhD Assistant New Mentor Anatomy & Cell Biology G protein signaling in zebrafish Professor (Genetics, Molecular & Cellular embryogenesis Biology) Ludewig, Gabriele, Professor Mentor Occupational & Enivronmental Environmental and genetic toxicology PhD Health (Human Toxicology) Lynch, Charles, MD, Professor Mentor Epidemiology Population-based research that involves PhD (Pathology) a cancer surveillance program (Iowa Cancer Registry) and cancer epidemiology, cancer pathology, and environmental epidemiology Mahajan, Vinit, MD, Assistant New Mentor Ophthalmology & Visual Vitreoretinal disease PhD Professor Sciences (Molecular & Cellular Biology) Maury, Wendy, PhD Professor Mentor Microbiology Admissions Committee, Regulation of lentiviral cell tropism (Molecular & Cellular Biology) Executive Committee McCarter, Linda, PhD Professor Mentor Microbiology Signal transduction and regulation of gene expression in bacteria McCray, Paul, MD Professor Mentor Pediatrics Rotation Mentor Development of for (Microbiology, Genetics, genetic diseases; of Informatics, Human Toxicology, ; and Molecular & Cellular Biology, characterization of antimicrobial peptide Translational Biomedicine) genes McNamara, James, Associate New Mentor Internal Medicine RNA-based technologies to understand PhD Professor (Molecular & Cellular Biology, and treat disorders of the nervous Neuroscience) system Miller, Francis, MD Professor Mentor Internal Medicine Dissertation Mentor, Role of reactive oxygen species in (Anatomy & Cell Biology, Free Admissions Committee vascular disease Radical & Radiation Biology) Morita, Craig, MD, Associate Mentor Internal Medicine Nonpeptide antigen recognition by PhD Professor (Immunology) gamma-delta T cells

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Moye-Rowley, Scott, Professor Mentor Molecular Physiology & Transcriptional control of oxidative PhD Biophysics stress tolerance; eukaryotic multidrug (Genetics, Molecular & Cellular resistance Biology) Murray, Jeffrey, MD Professor Mentor Pediatrics Dissertation Mentor Human molecular and developmental (Biology, Epidemiology, genetics Anatomy & Cell Biology, Genetics, Translational Biomedicine) Narayanan, Assistant New Mentor Neurology Rotation Mentor Cognitive dysfunction in Parkinson’s Nandakumar, MD, Professor (Neuroscience) disease PhD Nauseef, William, MD Professor Mentor Internal Medicine Human polymorphonuclear neutrophil (Microbiology, Immunology) metabolism and function Nopoulos, Peg, MD Professor Mentor Psychiatry Dissertation Mentor, Brain structure/function relationships (Neuroscience) Executive Committee using MRI and cognitive/behavioral assessment Norian, Lyse, PhD Assistant New Mentor Admissions Committee Cell and molecular biology of tumor- Professor (Immunology) derived immune dysfunction O'Dorisio, Sue, MD, Professor Mentor Pediatrics Dissertation Mentor Nervous system tumors of childhood PhD (Neuroscience, Translational Biomedicine) Paulsen, Jane, PhD Professor Mentor Psychiatry Neuropsychology (Neurology, Neuroscience) Peek-Asa, Corinne, Professor Mentor Occupational & Environmental Dissertation Mentor Workplace violence, childhood injuries, PhD Health and injuries in the elderly (Epidemiology, Translational Biomedicine) Perlman, Stanley, MD, Professor Mentor Microbiology Dissertation Mentor Pathogenesis of -induced PhD (Immunology, Neuroscience, demyelination Translational Biomedicine)

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Pieper, Andrew, MD, Associate New Mentor Psychiatry Dissertation Mentor Discovery of new treatments for PhD Professor (Free Radical & Radiation neuropsychiatric disease Biology, Human Toxicology, Molecular & Cellular Biology, Molecular Physiology & Biophysics, Neuroscience) Piper, Robert, PhD Professor Mentor Molecular Physiology & Dissertation Mentor Mechanisms governing the movement Biophysics of proteins in eukaryotes (Internal Medicine, Genetics) Potash, James, MD Professor Mentor Psychiatry Dissertation Mentor, Bipolar disorder, depression, and Head (Genetics, Neuroscience) Psychiatry Department epigenetics, genetics, methylation, Head mood, sequencing Price, David, PhD Professor Mentor Biochemistry Dissertation Mentor Discovering connections between (Molecular & Cellular Biology) transcription elongation and RNA processing , HIV replication and cancer Pufall, Miles, PhD Assistant New Mentor Biochemistry Admissions Committee Fine-tuning protein function Professor (Molecular & Cellular Biology) Quelle, Dawn, PhD Associate Mentor Pharmacology Dissertation Mentor, Molecular mechanisms of growth Professor (Molecular & Cellular Biology) Admissions Committee control; tumor suppressors; cyclins; cyclin-dependent kinases Raghavan, Madhavan, Associate Mentor Biomedical Engineering Biomechanics of biological and PhD Professor engineered soft tissues and swallowing Rahmouni, Kamal, Associate Mentor Pharmacology Dissertation Mentor Molecular mechanisms of energy PhD Professor (Internal Medicine, homeostasis and autonomic Neuroscience, Molecular & cardiovascular function Cellular Biology) Reinhardt, Joseph, Professor Mentor Biomedical Engineering Biomedical Engineering Medical imaging, image and signal PhD and Head (Informatics) Department Head processing Richerson, George, Professor Mentor Neurology Dissertation Mentor, Serotonin effects on brain function, MD, PhD and Head (Molecular Physiology & Executive Comimttee, GABA mechanisms in epilepsy Biophysics, Neuroscience, Neurology Department Molecular & Cellular Biology) Head

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Robertson, Janice, Assistant New Mentor Molecular Physiology & Energentics of membrane protein PhD Professor Biophysics assembly

Robertson, Larry, PhD Professor Mentor Occupational & Environmental Human Toxicology Mechanisms of toxicity of environmental Health Program Director contaminants (Free Radical & Radiation Biology, Human Toxicology) Romitti, Paul, PhD Professor Mentor Epidemiology Epidemilogy of congenital and inherited (Human Toxicology) disorders, reproductive molecular epidemiology Rosenthal, Gary, MD Professor Mentor Internal Medicine Executive Committee, quality assessment, and Interim (Epidemiology, Translational Internal Medicine provider performance, organizational Head Biomedicine) Department Interim determinants of patient outcomes, role Head, CTSA Director of the Department of Veterans Affairs in the US health care delivery system Russo, Andrew, PhD Professor Mentor Molecular Physiology & Dissertation Mentor, Control of gene expression in the neural Biophysics Integrating Discovery & crest and neurons (Genetics, Molecular & Cellular Educational Activities Biology, Neuroscience, Committee Translational Biomedicine) Rutkowski, D. Thomas, Associate Mentor Anatomy & Cell Biology Integrating Discovery & Mechanisms of adaptation to chronic PhD Professor (Molecular & Cellular Biology) Educational Activities cellular stresses in physiology and Committee disease Scheetz, Todd, PhD Associate Mentor Ophthalmology & Visual Rotation Mentor , -scale analysis Professor Sciences of sequences and expression data (Biomedical Eng, Genetics, Informatics) Schlievert, Patrick, Professor Mentor Microbiology Microbiology Department Molecular pathogenesis, drug discovery, PhD and Head (Internal Medicine, Immunology) Head and immunology; Staphylococcus aureus, Streptococci and Enterococci

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Schultz, Michael, PhD Associate New Mentor Radiology Development of synthetic-bioactive Professor (Internal Medicine, Radiation molecular targeting vectors for imaging Oncology, Free Radical & and therapy of cancer Radiation Biology, Human Toxicology) Segaloff, Deborah, Professor Mentor Molecular Physiology & Signaling by G protein-coupled PhD Biophysics receptors; reproductive Shea, Madeline, PhD Professor Mentor Biochemistry Fostering Undergraduate Regulatory protein interactions in signal (Translational Biomedicine) Talent-Uniting Research transduction, allosteric mechanism of and Education in cooperative calcium binding to Biomedicine Program calmodulin Director Sheffield, Val, MD, Professor Mentor Pediatrics Dissertation Mentor Molecular genetics of human hereditary PhD (Genetics, Informatics, disease Molecular & Cellular Biology) Sigmund, Curt, PhD Professor Mentor Pharmacology Dissertation Mentor, Molecular genetics and molecular and Head (Internal Medicine, Molecular Pharmacology biology of the renin-angiotensin system Physiology & Biophysics, Department Head and hypertension Molecular & Cellular Biology, Genetics, Informatics, Neuroscience, Translational Biomedicine) Sluka, Kathleen, PhD Professor Mentor Dissertation Mentor Neurobiology of pain and pain inhibition (Neuroscience, Molecular & Cellular Biology) Smith, Richard, MD Professor Mentor Otolaryngology Dissertation Mentor Inherited hearing impairment (Internal Medicine, Genetics, Immunology, Informatics, Molecular & Cellular Biology, Molecular Physiology & Biophysics, Neuroscience, Translational Biomedicine) Snetselaar, Linda, RD, Professor Mentor Epidemiology Nutritional epidemiology, nutrituion PhD (Internal Medicine) intervention clinical trials

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Snyder, Peter, MD Professor Mentor Internal Medicine Rotation Mentor Structure and function of the epithelial (Molecular Physiology & sodium channel and its role in Biophysics, Molecular & Cellular hypertension and other disorders of Biology) sodium homeostasis Spies, Ashley, PhD Assistant Mentor Biochemistry Fundamental properties of protein- Professor (Medicinal & Natural Products ligand interactions Chemistry) Spies, Maria, PhD Associate Mentor Biochemistry Single-molecule biochemistry of DNA Professor Repair machines Spitz, Douglas, PhD Professor Mentor Radiation Oncology Dissertation Mentor, Free Nitric oxide toxicology, (Free Radical & Radiation Radical & Radiation deprivation-induced cytotoxicity in Biology, Human Toxicology) Biology Program human tumor cells Director, Executive Committee Stapleton, Jack, MD Professor Mentor Internal Medicine Dissertation Mentor Epidemiology and effects of co-infection (Molecular & Cellular Biology, of hepatitis C virus (HCV), human GB Microbiology, Translational virus type C and HIV Biomedicine) Stipp, Chris, PhD Associate Mentor Biology Cellular and molecular analysis of the Professor (Molecular Physiology & nervous system Biophysics, Neuroscience) Stoltz, David, MD, PhD Associate New Mentor Internal Medicine Dissertation Mentor, Pathogenesis of cystic fibrosis related Professor (Biomedical Engineering, Admissions Committee, airway infections Molecular Physiology & Integrating Discovery & Biophysics) Educational Activities Committee, Course Director Stone, Edwin, MD, Professor Mentor Ophthalmology & Visual Dissertation Mentor Molecular genetics of inherited eye PhD Sciences diseases (Genetics, Informatics, Translational Biomedicine) Strack, Stefan, PhD Professor Mentor Pharmacology Dissertation Mentor Protein phosphatases in neuronal signal (Molecular & Cellular Biology, transduction Neuroscience)

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Sutterwala, Fayyaz, Associate Mentor Internal Medicine Dissertation Mentor, Biology of the NOD-like receptor family MD, PhD Professor (Immunology, Molecular & Admissions Committee, in infection and inflammation Cellular Biology) Recruitment Committee Tan, Kai, PhD Associate New Mentor Internal Medicine Rotation Mentor Gene regulatory networks and Professor (Biomedical Engineering, molecular pathways in human diseases Genetics, Informatics) Taylor, Eric, PhD Assistant New Mentor Biochemistry Dissertation Mentor Molecular mechanisms regulating Professor (Molecular & Cellular Biology) mitochondrial function in disease Tootle, Tina, PhD Assistant Mentor Anatomy & Cell Biology Molecular mechanisms of prostaglandin Professor (Genetics, Molecular & Cellular signaling Biology) Torner, Jim, PhD Professor Mentor Epidemiology Dissertation Mentor, Design and analysis of clinical trials and and Head (Informatics, Translational Epidemiology prognostic factors Biomedicine) Department Head Tranel, Daniel, PhD Professor Mentor Neurology Dissertation Mentor, Systems/behavioral neuroanatomical (Neuroscience, Informatics) Executive Committee, substrates of complex behavior human Neuroscience Program learning and memory Director, Assoc Dean Grad & Postdoc Studies Usachev, Yuriy, PhD Associate Mentor Pharmacology Admissions Committee Ca2+ signaling and control of pain- Professor (Neuroscience) conducting pathways Varga, Steve, PhD Associate Mentor Microbiology Immunology Program Viral immunology and immunopathology Professor (Immunology) Director Vyas, Yatin, MD, Professor Mentor Pediatrics Epigenetic regulation of the transcription MBBS (Immunology, Molecular & Program of Th1-network genes by Cellular Biology) WASP Wallace, Robert, MD Professor Mentor Epidemiology Dissertation Mentor Epidemiology of aging, cancer (Internal Medicine, Translational epidemiology Biomedicine) Wallrath, Lori, PhD Professor Mentor Biochemistry Eukaryotic chromatin structure and (Genetics, Molecular & Cellular gene expression; molecular Biology) mechanisms of gene silencing in Drosophila

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Table 2. Participating Faculty Members (continued)

Training Primary (& Secondary) Name/Degree(s) Rank Designation Appointment(s) Program Participation Research Interest Washington, Todd, Associate Mentor Biochemistry Dissertation Mentor, Mechanisms of enzymes involved in PhD Professor (Free Radical & Radiation Admissions Committee DNA replication and DNA repair Biology, Molecular & Cellular Biology) Weeks, Daniel, PhD Professor Mentor Biochemistry Dissertation Mentor Molecular mechanisms of early (Molecular & Cellular Biology) embryogenesis and cardiogenesis Weigel, Ron, MD, PhD Professor Mentor Surgery Dissertation Mentor, Determining mechanisms of hormone and Head (Biochemistry, Molecular Surgery Department response in breast cancer Physiology & Biophysics) Head Weiner, George, MD Professor Mentor Internal Medicine Dissertation Mentor, Immune response to lymphoma; (Immunology, Informatics, Executive Committee, bispecific therapeutic antibodies. Translational Biomedicine) Cancer Center Director Weiss, Jerrold, PhD Professor Mentor Internal Medicine Rotation Mentor, Innate mammalian antibacterial defense (Microbiology, Immunology, Admissions Committee mechanisms Translational Biomedicine, Human Toxicology) Welsh, Michael, MD Professor Mentor Internal Medicine Dissertation Mentor, Biology of cystic fibrosis; structure and (Molecular Physiology & Executive Committee function of ion channels; pathogenesis Biophysics, Molecular & Cellular of lung disease Biology, Neuroscience, Genetics, Informatics, Translational Biomedicine) Wemmie, John, MD, Professor Mentor Psychiatry Dissertation Mentor Genetic manipulation in mice to study PhD (Molecular Physiology & the effects of Acid Sensing Ion Biophysics, Neuroscience) Channels (ASICs) on behavior Willour, Virgina, PhD Associate New Mentor Psychiatry Dissertation Mentor Identifying genetic and epigenetic risk Professor (Genetics, Neuroscience) factors for suicidal behavior Wilson, Mary, MD Professor Mentor Internal Medicine Dissertation Mentor Immunobiology, genetics, and molecular (Microbiology, Epidemiology, biology of visceral leishmaniasis in Immunology, Molecular & murine and human hosts Cellular Biology, Genetics, Translational Biomedicine)

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