Barbara Mcclintock
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Research Plant Geneticist, USDA-ARS Professor, Department
ROGER PHILIP WISE Research Plant Geneticist, USDA-ARS Professor, Department of Plant Pathology and Microbiology Iowa State University Ames, IA 50011-1020 Phone: (515) 294-9756 Fax: (515) 294-9420 E-mail: [email protected] ; [email protected] Web: http://wiselab.org/ ; http://barleygenome.org/ Database: http://plexdb.org/ ; http://www.hordeumtoolbox.org/ A. Professional Preparation Michigan State University Physiology B.S. (High Honor), 1972-1976 Michigan State University Genetics Ph.D., 1978-1983 University of Florida Mol Plant-Microbe Interact Postdoctoral, 1984-1986 Max-Planck-Institut, Köln Plant Molecular Biology Postdoctoral, 1987-1989 B. Appointments 2015 – present ST-00 Cat 1 Research Geneticist, USDA-ARS / Professor, ISU 2003-2014 GS-15 Cat 1 Research Geneticist, USDA-ARS / Professor, ISU 2000-2002 GS-14 Cat 1 Research Geneticist, USDA-ARS / Professor, ISU 1998-2000 GS-14 Cat 1 Research Geneticist, USDA-ARS / Associate Professor, ISU 1994-1998 GS-13 Cat 1 Research Geneticist, USDA-ARS / Associate Professor, ISU 1989-1993 GS-12 Cat 1 Research Geneticist, USDA-ARS / Assistant Professor, ISU Iowa State Interdepartmental Program Affiliations: 1990-present Interdepartmental Genetics 1999-present Interdepartmental Bioinformatics & Computational Biology Iowa State Plant Sciences Institute – Center Membership: 1999-present Center for Plant Responses to Environmental Stresses 1999-present Center for Plant Genomics 1999-present Center for Plant Transformation and Gene Expression C. PROFESSIONAL AFFILIATIONS American Association for the Advancement of Science American Phytopathological Society International Society for Molecular Plant-Microbe Interactions Genetics Society of America American Association of Plant Biologists D. HONORS AND AWARDS 2015: Elected Fellow of AAAS 2011: USDA Secretary's Honor Award: Helping America promote sustainable agricultural production and biotechnology exports as America works to increase food security. -
書 名 等 発行年 出版社 受賞年 備考 N1 Ueber Das Zustandekommen Der
書 名 等 発行年 出版社 受賞年 備考 Ueber das Zustandekommen der Diphtherie-immunitat und der Tetanus-Immunitat bei thieren / Emil Adolf N1 1890 Georg thieme 1901 von Behring N2 Diphtherie und tetanus immunitaet / Emil Adolf von Behring und Kitasato 19-- [Akitomo Matsuki] 1901 Malarial fever its cause, prevention and treatment containing full details for the use of travellers, University press of N3 1902 1902 sportsmen, soldiers, and residents in malarious places / by Ronald Ross liverpool Ueber die Anwendung von concentrirten chemischen Lichtstrahlen in der Medicin / von Prof. Dr. Niels N4 1899 F.C.W.Vogel 1903 Ryberg Finsen Mit 4 Abbildungen und 2 Tafeln Twenty-five years of objective study of the higher nervous activity (behaviour) of animals / Ivan N5 Petrovitch Pavlov ; translated and edited by W. Horsley Gantt ; with the collaboration of G. Volborth ; and c1928 International Publishing 1904 an introduction by Walter B. Cannon Conditioned reflexes : an investigation of the physiological activity of the cerebral cortex / by Ivan Oxford University N6 1927 1904 Petrovitch Pavlov ; translated and edited by G.V. Anrep Press N7 Die Ätiologie und die Bekämpfung der Tuberkulose / Robert Koch ; eingeleitet von M. Kirchner 1912 J.A.Barth 1905 N8 Neue Darstellung vom histologischen Bau des Centralnervensystems / von Santiago Ramón y Cajal 1893 Veit 1906 Traité des fiévres palustres : avec la description des microbes du paludisme / par Charles Louis Alphonse N9 1884 Octave Doin 1907 Laveran N10 Embryologie des Scorpions / von Ilya Ilyich Mechnikov 1870 Wilhelm Engelmann 1908 Immunität bei Infektionskrankheiten / Ilya Ilyich Mechnikov ; einzig autorisierte übersetzung von Julius N11 1902 Gustav Fischer 1908 Meyer Die experimentelle Chemotherapie der Spirillosen : Syphilis, Rückfallfieber, Hühnerspirillose, Frambösie / N12 1910 J.Springer 1908 von Paul Ehrlich und S. -
LSU WIS October 2016 Newsletter
Volume 1 | Issue 2 LSU Women in Science Oct. 31st, 2016 Thank you to everyone who attended our first meeting of the semester at the beginning of October! For those of you who couldn’t make it: We had a great conversation about the importance of women role models and mentors in positions of leadership and how that influences our own path in science. We are excited about the enthusiam and direction of LSU Women in Science and look forward to seeing you all at our next meeting! -Your LSU WIS Leadership Team The next meeting will be open to everyone. Come as you are and bring anyone you want. It doesn't matter if you're male, female, neutral, trans, gay, straight, black, white, brown, or purple, if you love science and want to be part of the conversation, join us! Fall 2016 meetings Meetings will be the first Tuesday of the month at 5pm! The December meeting will be a social – More information will be announced in the coming weeks! NEXT MEETING Tuesday Nov 1st @ 5pm Renewable and Natural “Life is not easy for any of Resources Building Rm 141 us. But what of that? We must have perseverance and above all confidence in ourselves. We must believe that we are gifted for something and that this thing must be attained.” – Marie Curie Contact us Kelcee Smith [email protected] Cassandra Skaggs [email protected] Julie Butler [email protected] Amie Settlecowski [email protected] WOMEN IN SCIENCE OCTOBER NEWSLETER 1 Perception of Women in Science: #distractinglysexy By Cassandra Skaggs Many of us recall the #distractinglysexy social media explosion that occurred in 2015 over Dr. -
Introduction and Historical Perspective
Chapter 1 Introduction and Historical Perspective “ Nothing in biology makes sense except in the light of evolution. ” modified by the developmental history of the organism, Theodosius Dobzhansky its physiology – from cellular to systems levels – and by the social and physical environment. Finally, behaviors are shaped through evolutionary forces of natural selection OVERVIEW that optimize survival and reproduction ( Figure 1.1 ). Truly, the study of behavior provides us with a window through Behavioral genetics aims to understand the genetic which we can view much of biology. mechanisms that enable the nervous system to direct Understanding behaviors requires a multidisciplinary appropriate interactions between organisms and their perspective, with regulation of gene expression at its core. social and physical environments. Early scientific The emerging field of behavioral genetics is still taking explorations of animal behavior defined the fields shape and its boundaries are still being defined. Behavioral of experimental psychology and classical ethology. genetics has evolved through the merger of experimental Behavioral genetics has emerged as an interdisciplin- psychology and classical ethology with evolutionary biol- ary science at the interface of experimental psychology, ogy and genetics, and also incorporates aspects of neuro- classical ethology, genetics, and neuroscience. This science ( Figure 1.2 ). To gain a perspective on the current chapter provides a brief overview of the emergence of definition of this field, it is helpful -
Barbara Mcclintock's World
Barbara McClintock’s World Timeline adapted from Dolan DNA Learning Center exhibition 1902-1908 Barbara McClintock is born in Hartford, Connecticut, the third of four children of Sarah and Thomas Henry McClintock, a physician. She spends periods of her childhood in Massachusetts with her paternal aunt and uncle. Barbara at about age five. This prim and proper picture betrays the fact that she was, in fact, a self-reliant tomboy. Barbara’s individualism and self-sufficiency was apparent even in infancy. When Barbara was four months old, her parents changed her birth name, Eleanor, which they considered too delicate and feminine for such a rugged child. In grade school, Barbara persuaded her mother to have matching bloomers (shorts) made for her dresses – so she could more easily join her brother Tom in tree climbing, baseball, volleyball, My father tells me that at the and football. age of five I asked for a set of tools. He My mother used to did not get me the tools that you get for an adult; he put a pillow on the floor and give got me tools that would fit in my hands, and I didn’t me one toy and just leave me there. think they were adequate. Though I didn’t want to tell She said I didn’t cry, didn’t call for him that, they were not the tools I wanted. I wanted anything. real tools not tools for children. 1908-1918 McClintock’s family moves to Brooklyn in 1908, where she attends elementary and secondary school. In 1918, she graduates one semester early from Erasmus Hall High School in Brooklyn. -
I. Hox Genes 2
School ofMedicine Oregon Health Sciences University CERTIFICATE OF APPROVAL This is certify that the Ph.D. thesis of WendyKnosp has been approved Mentor/ Advisor ~ Member Member QUANTITATIVE ANALYSIS OF HOXA13 FUNCTION IN THE DEVELOPING LIMB By Wendy M. lt<nosp A DISSERTATION Presented to the Department of Molecular and Medical Genetics and the Oregon Health & Science University School of Medicine in partial fulfillment of the requirements for the degree of Doctor of Philosophy August 2006 TABLE OF CONTENTS LIST OF FIGURES iv LIST OF ABBREVIATIONS vii ACKNOWLEDGEMENTS X ABSTRACT xii CHAPTER 1: Introduction 1 I. Hox genes 2 A. Discovery of Hox genes in Drosophila melanogaster 2 B. Hox cluster colinearity and conservation 7 C. Human Hox mutations 9 D. Hoxa13: HFGS and Guttmacher syndromes 10 II. The Homeodomain 12 A. Homeodomain structure 12 B. DNA binding 14 Ill. Limb development 16 A. Patterning of the limb axes 16 B. Digit formation 20 C. lnterdigital programmed cell death 21 IV. BMPs and limb development 23 A. BMP signaling in the limb 23 B. BMP target genes 27 V. Hoxa13 and embryonic development 30 A. The Hoxa13-GFP mouse model 30 B. Hoxa13 mutant phenotypes 34 C. HOXA 13 homeodomain 35 D. HOXA 13 protein-protein interactions 36 E. HOXA 13 target genes 37 VI. Hypothesis and Rationale 39 CHAPTER 2: HOXA13 regulates Bmp2 and Bmp7 40 I. Abstract 42 II. Introduction 43 Ill. Results 46 IV. Discussion 69 v. Materials and Methods 75 VI. Acknowledgements 83 11 CHAPTER 3: Quantitative analysis of HOXA13 function 84 HOXA 13 regulation of Sostdc1 I. -
DNA Replication
Introduction to genome biology Sandrine Dudoit and Robert Gentleman Bioconductor short course Summer 2002 © Copyright 2002, all rights reserved Outline • Cells and cell division • DNA structure and replication •Proteins • Central dogma: transcription, translation • Pathways A brief history Gregor Mendel (1823(1823---1884)1884) Thomas Hunt Morgan (1866(1866---1945)1945) Francis Crick (1916(1916---)))) James D. Watson (1928(1928---)))) From chromosomes to proteins Cells Cells • Cells: the fundamental working units of every living organism. • Metazoa: multicellular organisms. E.g. Humans: trillions of cells. • Protozoa: unicellular organisms. E.g. yeast, bacteria. Cells • Each cell contains a complete copy of an organism’s genome, or blueprint for all cellular structures and activities. • Cells are of many different types (e.g. blood, skin, nerve cells), but all can be traced back to a single cell, the fertilized egg. Cell composition • 90% water. • Of the remaining molecules, dry weight – 50% protein – 15% carbohydrate – 15% nucleic acid – 10% lipid – 10% miscellaneous. • By element: 60% H, 25% O, 12%C, 5%N. The genome • The genome is distributed along chromosomes, which are made of compressed and entwined DNA. • A (protein-coding) gene is a segment of chromosomal DNA that directs the synthesis of a protein. Eukaryotes vs. prokaryotes Eukaryotes vs. prokaryotes • Prokaryotic cells: lack a distinct, membrane-bound nucleus. E.g. bacteria. • Eukaryotic cells: distinct, membrane- bound nucleus. Larger and more complex in structure than prokaryotic cells. E.g. mammals, yeast. The eukaryotic cell The eukaryotic cell • Nucleus: membrane enclosed structure which contains chromosomes, i.e., DNA molecules carrying genes essential to cellular function. • Cytoplasm: the material between the nuclear and cell membranes; includes fluid (cytosol), organelles, and various membranes. -
The Contributions of George Beadle and Edward Tatum
| PERSPECTIVES Biochemical Genetics and Molecular Biology: The Contributions of George Beadle and Edward Tatum Bernard S. Strauss1 Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, Illinois 60637 KEYWORDS George Beadle; Edward Tatum; Boris Ephrussi; gene action; history It will concern us particularly to take note of those cases in Genetics in the Early 1940s which men not only solved a problem but had to alter their mentality in the process, or at least discovered afterwards By the end of the 1930s, geneticists had developed a sophis- that the solution involved a change in their mental approach ticated, self-contained science. In particular, they were able (Butterfield 1962). to predict the patterns of inheritance of a variety of charac- teristics, most morphological in nature, in a variety of or- EVENTY-FIVE years ago, George Beadle and Edward ganisms although the favorites at the time were clearly Tatum published their method for producing nutritional S Drosophila andcorn(Zea mays). These characteristics were mutants in Neurospora crassa. Their study signaled the start of determined by mysterious entities known as “genes,” known a new era in experimental biology, but its significance is to be located at particular positions on the chromosomes. generally misunderstood today. The importance of the work Furthermore, a variety of peculiar patterns of inheritance is usually summarized as providing support for the “one gene– could be accounted for by alteration in chromosome struc- one enzyme” hypothesis, but its major value actually lay both ture and number with predictions as to inheritance pattern in providing a general methodology for the investigation of being quantitative and statistical. -
150 Years of Research at the United States Department of Agriculture
United States Department of Agriculture Agricultural Research Service 150 Years of Research at June 2013 the United States Department of Agriculture: Plant Introduction and Breeding I Cover photo: The stately building that once housed the U.S. Department of Agriculture in Washington, D.C., ca. 1890. (This photo is preserved in the USDA History Collection, Special Collections, National Agricultural Library.) II United States Department of Agriculture Agricultural Research Service 150 Years of Research at June 2013 the United States Department of Agriculture: Plant Introduction and Breeding R.J. Griesbach Griesbach is Deputy Assistant Administrator, Office of Technology Transfer, USDA, Agricultural Research Service, Beltsville, MD. i Abstract Griesbach, R.J. 2013. 150 Years of Research at the While supplies last, single copies of this publication United States Department of Agriculture: can be obtained at no cost from Robert J. Griesbach, Plant Introduction and Breeding. U.S. Department USDA-ARS, Office of Technology Transfer, 5601 of Agriculture, Agricultural Research Service, Sunnyside Avenue, Room 4-1159, Beltsville, MD Washington, DC. 20705; or by email at [email protected]. The U.S. Department of Agriculture celebrated its Copies of this publication may be purchased in various 150th anniversary in 2012. One of the primary formats (microfiche, photocopy, CD, print on demand) functions of the USDA when it was established in 1862 from the National Technical Information Service, 5285 was “to procure, propagate, and distribute among the people new Port Royal Road, Springfield, VA 22161, (800) 553- and valuable seeds and plants.” The U.S. Government first 6847, www.ntis.gov. became involved in new plant introductions in 1825 when President John Quincy Adams directed U.S. -
Genes, Genomes and Genetic Analysis
© Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION UNIT 1 © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FORDefining SALE OR DISTRIBUTION and WorkingNOT FOR SALE OR DISTRIBUTION with Genes © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION Chapter 1 Genes, Genomes, and Genetic Analysis Chapter 2 DNA Structure and Genetic Variation © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION © Molekuul/Science Photo Library/Getty Images. © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION © Jones & Bartlett Learning, LLC. NOT FOR SALE OR DISTRIBUTION 9781284136609_CH01_Hartl.indd 1 08/11/17 8:50 am © Jones & Bartlett Learning, LLC -
Mendel, No. 14, 2005
THE MENDEL NEWSLETTER Archival Resources for the History of Genetics & Allied Sciences ISSUED BY THE LIBRARY OF THE AMERICAN PHILOSOPHICAL SOCIETY New Series, No. 14 March 2005 A SPLENDID SUCCESS As promised in this newsletter last year, the American Philosophical Society Library hosted the October 2004 conference, “Descended from IN THIS ISSUE Darwin: Insights into American Evolutionary Studies, 1925-1950”. In total, eighteen speakers and over thirty participants spent two days discussing the • The Correspondence of the Tring current state of scholarship in this area. Some papers focused on particular researchers and their theoretical projects. Others worked to place work from Museum at the Natural History the period into larger historical contexts. Professor Michael Ruse delivered Museum, London the keynote address, a popular lecture on the differences in emphasis when evolutionists present their work in public versus professional spheres. It • The Cyril Dean Darlington Papers was a capacity crowd and a roaring success. Thanks to the ‘Friends of the Library’ for the grand reception. • Joseph Henry Woodger (1894-1981) This conference had a real buzz about it. I had the sense we scholars Papers at University College London are on the brink of significant developments in our understanding of the period. Moreover, considerable progress is being made on how we might • Where to Look Next?: Agricultural relate this period to research underway in the decades before and after. New Archives as Resources for the History archives, new ideas, new opportunities. of Genetics As organiser, I’d like to express my thanks to the participants for the hard work done to prepare. -
Rollins Adams Emerson (1873-1947) Horticulturist Pioneer Plant Geneticist Administrator Inspiring Student Adviser Rosalind Morris University of Nebraska-Lincoln
University of Nebraska - Lincoln DigitalCommons@University of Nebraska - Lincoln Agronomy & Horticulture -- Faculty Publications Agronomy and Horticulture Department 1969 Rollins Adams Emerson (1873-1947) Horticulturist Pioneer Plant Geneticist Administrator Inspiring Student Adviser Rosalind Morris University of Nebraska-Lincoln Follow this and additional works at: http://digitalcommons.unl.edu/agronomyfacpub Part of the Agricultural Science Commons, Agriculture Commons, Agronomy and Crop Sciences Commons, Botany Commons, Horticulture Commons, Other Plant Sciences Commons, and the Plant Biology Commons Morris, Rosalind, "Rollins Adams Emerson (1873-1947) Horticulturist Pioneer Plant Geneticist Administrator Inspiring Student Adviser" (1969). Agronomy & Horticulture -- Faculty Publications. 901. http://digitalcommons.unl.edu/agronomyfacpub/901 This Article is brought to you for free and open access by the Agronomy and Horticulture Department at DigitalCommons@University of Nebraska - Lincoln. It has been accepted for inclusion in Agronomy & Horticulture -- Faculty Publications by an authorized administrator of DigitalCommons@University of Nebraska - Lincoln. ROLLINS ADAMS EMERSON (1873-1947) HORTICULTURIST PIONEER PLANT GENETICIST ADMINISTRATOR INSPIRING STUDENT ADVISER This biography was prepared by Rosa I ind Morris Department of Agronomy, University of Nebraska Lincoln, Nebraska 68503 and was presented in part at the Annual Meeting of The Nebraska Academy of Sciences, 1969. An abstract of the talk was published in the Proceedings of The Academy for 1969. ROLLINS ADAMS EMERSON (1873-1947) HORTICULTURIST, PIONEER PLANT GENETICIST, ADMINISTRATOR, INSPIRING STUDENT ADVISER Rosallnd Morris, Department of Agronomy, University of Nebraska, Lincoln, Nebraska The vigorous and highly productive life of Professor R. A. Emerson spanned 74 years and 7 months. His birth and death took place In New York State, but Nebraska nurtured his early development and schooling.