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Denis M. Dwyre, M.D.

Clinical Interests Dr. Dwyre has clinical responsibilities in hematopathology, including , and , as well as apheresis (the withdrawal of blood from a donor's body, removal of one or more components, and transfusion of the remaining blood back into the donor), which includes pediatric apheresis and progenitor-cell collection. He is involved in -related clinical research involving leukemia, lymphoma and apheresis.

Research/Academic Interests Dr. Dwyre's clinical research involves leukemia, lymphoma, and apheresis. Hematopathology — leukemia, lymphoma, flow cytometry. Apheresis — pediatric apheresis and progenitor cell collection.

Title Director, Hematopathology Professor Specialty and Laboratory , Pathology - Clinical, Pathology - Hematopathology, Pathology - Apheresis Department Pathology and Laboratory Medicine

Division Pathology

Address/Phone Pathology Building, 4400 V St. Sacramento, CA 95817 Phone: 916-734-2525

Additional Phone Fax: 916-734-2560 Referrals: 800-4-UCDAVIS (800-482-3284) Education M.D., University of Cincinnati College of Medicine, Cincinnati OH 1994 B.S., UC Davis, Davis CA 1985 Internships Pathology, UC Davis Medical Center, Sacramento CA 1994-1995

Residency Pathology/, UC Davis Medical Center, Sacramento CA 1995-2000

Fellowships Hematopathology, UC Davis Medical Center, Sacramento CA 2000-2001 , University of Iowa, Iowa City IA 2003-2005 Board Certifications American Board of Internal Medicine, 2000 American Board of Pathology, Blood Banking/Transfusion Medicine, 2005 American Board of Pathology, , 1998 American Board of Pathology, Hematology, 2001

Denis M. Dwyre, M.D.

Professional Memberships American Association of Blood Banks American College of (Internal Medicine) American Society for Clinical Pathology American Society of Hematology College of American Pathologists Society of Hematopathology Honors and Awards Excellence in , University of Cincinnati, 1994 Excellence in Gross Anatomy, University of Cincinnati, 1991 Select Recent Publications Gosselin RC, Carlin AC, Dwyre DM. Comparison of the BioRad Variant and Primus Ultra2 high- pressure liquid (HPLC) instruments for the detection of variant hemoglobins. Int J Lab Hematol. 2011 Apr;33(2):159-67. doi: 10.1111/j.1751-553X.2010.01260.x. Epub 2010 Sep 14. Raife TJ, Dwyre DM, Stevens JW, Erger RA, Leo L, Wilson KM, Fernndez JA, Wilder J, Kim HS, Griffin JH, Maeda N, Lentz SR. Human thrombomodulin knock-in mice reveal differential effects of human thrombomodulin on thrombosis and atherosclerosis. Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2509-17. Smith ZJ, Chu K, Espenson AR, Rahimzadeh M, Gryshuk A, Molinaro M, Dwyre DM, Lane S, Matthews D, Wachsmann-Hogiu S. Cell-phone-based platform for biomedical device development and education applications. PLoS One. 2011 Mar 2;6(3):e17150. Dwyre DM, Fernando LP, Holland PV. Hepatitis B, hepatitis C and HIV transfusion-transmitted in the 21st century. Vox Sang. 2011 Jan;100(1):92-8. Trikha R, Yeung C, Modjtahedi S, Martin S, Dwyre DM, Telander DG. B-cell lymphoma line (Raji) viability and surface marker expression minimally affected by 20- and 25-gauge vitrectomy systems analyzed by flow cytometry. Retina. 2010 Oct;30(9):1505-10. Bleile MJ, Rijhsinghani A, Dwyre DM, Raife TJ. Successful use of maternal blood in the management of severe hemolytic of the fetus and newborn due to anti-Kp(b). Transfus Apher Sci. 2010 Dec;43(3):281-3. Epub 2010 Oct 15. Dwyre DM, Dursteler B, Nashelsky M, Friedman KD, Raife TJ. Value of ADAMTS13 activity and inhibitor in the postmortem diagnosis of thrombotic thrombocytopenic purpura. J Clin Apheresis 2009;24:106-110. Dwyre DM, Holland PV. Transfusion associated graft-versus-host disease. Vox Sang 2008;95:85- 93.

Denis M. Dwyre, M.D.

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