Date of Document: December 13, 2016

CURRICULUM VITAE

Horatiu Olteanu MD, PhD

Associate Professor Department of Division of Administration

OFFICE ADDRESS: Froedtert/MCW Laboratory Building 9200 W Wisconsin Ave Milwaukee, WI 53226

CITIZENSHIP: U.S.A

EDUCATION: 09/1990 - 09/1996 M.D., "Iuliu Hatieganu" University of and , Cluj-Napoca, Romania 07/1998 - 06/2003 Ph.D. (Biochemistry), University of Nebraska, Lincoln, NE

POSTGRADUATE TRAINING AND APPOINTMENTS: 04/1997 - 03/1998 Intern, Cardiothoracic , "Nicolae Stancioiu" Heart Institute, Calea Motilor 19-21, Cluj-Napoca, Romania, 400001 04/1998 - 06/1998 Visiting Fellow, Cardiovascular , Robert Koch , Von-Reden-Str. 1, Gehrden, Germany, 30989 07/2003 - 06/2007 Resident, Anatomic and , University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9072 07/2007 - 06/2008 Fellow, Hematopathology, Medical College of Wisconsin Affiliated , 8701 Watertown Plank Road, Milwaukee, WI 53226

FACULTY APPOINTMENTS: 07/2008 - 06/2012 Assistant Professor, Department of Pathology, Division of Hematopathology, Medical College of Wisconsin, Milwaukee, WI 07/2012 - Present Associate Professor, Department of Pathology, Division of Hematopathology, Medical College of Wisconsin, Milwaukee, WI

ADMINISTRATIVE APPOINTMENTS: 09/2008 - Present Medical Director, Clinical , Wisconsin Diagnostic Laboratories, 9200 W Wisconsin Avenue, Milwaukee, WI 53226

EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: 07/2011 - Present Director, Hematopathology Fellowship, Department of Pathology, Division of Hematopathology, Medical College of Wisconsin, Milwaukee, WI 07/2011 - Present Director, Hematopathology and Flow Cytometry residency rotations, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI 11/2011 - Present Activity Director, Hematologic Malignancy Conference, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI 03/2015 - Present Chair, Clinical Competency Committee, Hematopathology Fellowship, Department of Pathology, Division of Hematopathology, Medical College of Wisconsin, Milwaukee, WI 04/2016 - Present Chair, Grand Rounds Committee, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI

HOSPITAL STAFF PRIVILEGES:

1 / 14 07/2008 - Present Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Ave., Milwaukee, WI 53226 07/2008 - Present Community Memorial Hospital, W180 N8085 Town Hall Rd., Menomonee Falls, WI 53052 07/2008 - 02/2011 Children's Hospital of Wisconsin, 9000 W Wisconsin Avenue, Wauwatosa, WI 53226 07/2012 - Present St. Joseph's Hospital, 3200 Pleasant Valley Rd, West Bend, WI 53095

SPECIALTY BOARDS AND CERTIFICATION:

Board Certified Issue Date Expiration Anatomic and Clinical Pathology 08/2007 12/2017 Pathology - 09/2008 12/2018

Licensure Number Issue Date Expiration Kansas License (inactive) #0432133 10/2006 06/2016 Wisconsin License #50870-020 09/2007 10/2017

AWARDS AND HONORS: 05/1996 Eli Lilly-Alsifcom Award for Outstanding Academic Performance, "Iuliu Hatieganu" University of Medicine and Pharmacy 03/2000 Milton E. Mohr Graduate Fellowship, University of Nebraska - Lincoln 03/2001 Bukey Memorial Graduate Fellowship, University of Nebraska - Lincoln 03/2002 Holling Family Teaching Assistant Award, University of Nebraska - Lincoln 01/2003 Predoctoral Fellowship, American Heart Association 05/2004 Folsom Distinguished Dissertation Award, University of Nebraska - Lincoln 01/2007 Third Place - Podium Competition, John R. Rainey, MD Residents'/Fellows' Seminar, Texas Society of Pathologists Annual Meeting 12/2009 MCW Outstanding Medical Student Teacher for 2008-09, Pathology Course 04/2013 Distinguished Biochemistry Alumni Award, University of Nebraska - Lincoln 08/2013 Outstanding Faculty Service Award, Medical College of Wisconsin

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: 01/2000 - 12/2011 American Chemical Society 01/2000 - 06/2003 Phi Lambda Upsilon Chemical Honorary Society (University of Nebraska - Lincoln chapter) 11/2003 - 06/2007 Texas Society of Pathologists 01/2005 - 12/2016 College of American Pathologists 01/2005 - 12/2016 American Society for Clinical Pathology 01/2005 - 12/2016 United States and Canadian Academy of Pathology 01/2006 - 06/2007 North Texas Society of Pathologists 07/2008 - 12/2010 American Medical Association 01/2009 - 12/2016 Society for Hematopathology 01/2014 - 12/2016 International Clinical Cytometry Society 01/2014 - 12/2016 International Society for Advancement of Cytometry 08/2016 - Present Society for Academic Continuing

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: Editorial Board 08/2015 - Present Laboratory Medicine, Assistant Editor for Hematology Journal Review 03/2009 - Present Haematologica 03/2009 - Present Lab Medicine 04/2013 - Present and Laboratory Medicine 04/2013 - Present Annals of Diagnostic Pathology 04/2013 - Present Cytometry: Part B - Clinical Cytometry 06/2013 - Present Clinical Epidemiology

2 / 14 09/2013 - Present Journal of Hematology & 10/2013 - Present Journal of Clinical Laboratory Analysis 01/2014 - Present BMC Hematology 01/2014 - Present Clinical Case Reports 07/2014 - Present International Journal of Laboratory Hematology 06/2015 - Present Oncotarget 08/2016 - Present PLOS One

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: 09/2011 - Present Member, Dyad Operations Committee, Wisconsin Diagnostic Laboratories 03/2012 - Present Member, Capital Steering Committee, Wisconsin Diagnostic Laboratories 03/2014 - Present Member, Communications Committee, Wisconsin Diagnostic Laboratories

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: 05/2006 - Present Laboratory Inspector, Hematology and Flow Cytometry, College of American Pathologists 09/2009 - 09/2013 Member, Pathologist Recertification Individualized Self-Assessment Examination (PRISE) Committee, American Society for Clinical Pathology 03/2013 - 03/2015 Member, Education Committee, Society for Hematopathology 03/2013 - 03/2015 Co-chair, Case of the Quarter, Society for Hematopathology 09/2013 - Present Chair, PRISE Committee, American Society for Clinical Pathology 03/2015 - Present Chair, Case of the Quarter, Society for Hematopathology 11/2015 - Present Member, Hematology and Clinical Microscopy Resource Committee (HCMRC), College of American Pathologists

INTERNATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: 06/2015 - Present Member, USCAP Abstract Review Board, Hematopathology Section, United States and Canadian Academy of Pathology 12/2015 - Present Member, Education Committee, International Clinical Cytometry Society 01/2016 - Present Member, ICCS E-Learning Subcommittee, International Clinical Cytometry Society 01/2016 - Present Member, ICCS 2016 Program Committee, International Clinical Cytometry Society

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:

Active Peer Review Title: Role of Tumor Suppressor IRF-1 in Viral Lymphomagenesis Source: Thomas A. and Lorraine M. Rosenberg Award for Translational Cancer Research Role: Co-Investigator PI: Vera Tarakanova, PhD Dates: 05/01/2016 - 04/30/2018 Direct Funds: $80,000 (total for all years)

Title: lRF-1: A Brake to Limit Gammaherpesvirus and Pathogenesis Source: NIH Role: Co-Investigator PI: Vera Tarakanova, PhD Dates: 09/01/2016 - 08/31/2021 Direct Funds: $1,925,000 (total for all years)

INVITED LECTURES/WORKSHOPS/PRESENTATIONS: Local Horatiu Olteanu, Diagnostic and prognostic significance of CD200 expression in plasmacytic , Department of Pathology and Laboratory Medicine Grand Rounds, University of Wisconsin School of Medicine and , Madison, WI, 01/31/2013 Horatiu Olteanu, Prognostic significance of CD200 expression in immunoproliferative and posttransplant

3 / 14 lymphoproliferative disorders, Hematologic Malignancy and Transplantation Research Program, Medical College of Wisconsin Cancer Center, Milwaukee, WI, 02/14/2013 Horatiu Olteanu, in Hematologic Malignancies: The Use of Flow Cytometry in Identifying New Diagnostic and Prognostic Markers in Plasma Cell and Lymphoid Disorders, Biochemistry Annual Alumni Seminar, University of Nebraska, Lincoln, NE, 04/23/2013 Horatiu Olteanu, Clinicopathologic Analysis of the Impact of CD23 Expression in Hematologic Malignancies, Hematologic Malignancy and Transplantation Research Program, Medical College of Wisconsin Cancer Center, Milwaukee, WI, 10/10/2013 Horatiu Olteanu, Biomarker Discovery in Plasmacytic Neoplasms and Post-Transplant Lymphoproliferative Disorders, Department of Pathology, Microbiology and Laboratory Medicine Grand Rounds, Vanderbilt University School of Medicine, Nashville, TN, 11/13/2015

National Horatiu Olteanu, Evening slide seminar: Inflammatory pseudotumor of lymph node, The Midwestern Conference - Update Course in , Milwaukee, WI, 09/12/2008 - 09/14/2008 Horatiu Olteanu, Evening slide seminar: Histiocytic sarcoma, The Midwestern Conference - Update Course in Surgical Pathology, Milwaukee, 08/21/2009 - 08/23/2009 Horatiu Olteanu, Evening slide seminar: Blastic plasmacytoid dendritic cell , The Midwestern Conference - Update Course in Surgical Pathology, Milwaukee, WI, 08/21/2009 - 08/23/2009 Horatiu Olteanu, Evening slide seminar: Flow cytometry of Hodgkin , The Midwestern Conference - Update Course in Surgical Pathology, Milwaukee, WI, 05/14/2010 - 05/16/2010 Horatiu Olteanu, Diffuse Large B-Cell Lymphoma: An update on new entities, The Midwestern Conference - Update Course in Surgical Pathology, Milwaukee, WI, 09/09/2011 - 09/11/2011 Horatiu Olteanu, Immunodeficiency-Associated Lymphoproliferative Disorders, The Midwestern Conference – Update Course in Surgical Pathology, Milwaukee, WI, 09/14/2012 - 09/16/2012 Horatiu Olteanu, Diagnostic pitfalls in reactive and malignant lymphadenopathies, The Midwestern Conference – Update Course in Surgical Pathology, Milwaukee, WI, 09/20/2013 - 09/22/2013 Horatiu Olteanu, Diagnostic Challenges in CD5(+) Low-Grade B-Cell , The Midwestern Conference – Update Course in Surgical Pathology, Milwaukee, WI, 10/14/2016 - 10/16/2016

International Horatiu Olteanu, CSI Houston - Case Study Interpretations, 25th Annual International Clinical Cytometry Society Meeting, Houston, TX, 10/03/2010 - 10/05/2010 Horatiu Olteanu, Flow cytometric analysis in myeloid neoplasms, 2011 ASCP Annual Meeting / WASPaLM XXVI World Congress, Las Vegas, NV, 10/19/2011 - 10/22/2011 Horatiu Olteanu, Splenic Lymphomas: Classification and Advances in the Separation of Distinct Clinicopathologic and Molecular Entities – A SH/EAHP Workshop Proposal, 2013 USCAP Annual Meeting, Baltimore, MD, 03/02/2013 - 03/08/2013 Horatiu Olteanu, Flow cytometric evaluation of natural killer cell-associated receptors (NKRs), 2013 International Clinical Cytometry Society web presentation, 08/2013 - Present Horatiu Olteanu, Stewart Knoepp, Rebecca Wilcox., Maintenance of Certification and PRISE: Applying New and Validated Knowledge to Clinical Practice, 2013 ASCP Annual Meeting, Chicago, IL, 09/18/2013 - 09/21/2013 Horatiu Olteanu, Jose Plaza, Rebecca Wilcox, Problem areas in the interpretation of lymph node, cutaneous, and gastrointestinal biopsies - Presented by the faculty of PRISE, 2014 ASCP Annual Meeting, Tampa, FL, 10/08/2014 - 10/10/2014 Horatiu Olteanu, Normal and abnormal immunophenotypic patterns by flow cytometry, 2014 ASCP Annual Meeting, Tampa, FL, 10/08/2014 - 10/10/2014 Horatiu Olteanu, Yuri Fedoriw, Diagnostic Challenges in Low-Grade B-Cell Lymphomas, 2015 CAP Annual Meeting, Nashville, TN, 10/04/2015 - 10/07/2015 Horatiu Olteanu, Advanced flow cytometry-based diagnostic hematopathology: an integrated approach, 2015 ICCS Annual Meeting, Denver, CO, 10/11/2015 - 10/13/2015 Horatiu Olteanu, Clinical and pathologic features of aggressive B-cell lymphomas, 2015 IOCN Hematology Workshop, Cluj-Napoca, Romania, 11/05/2015 - 11/07/2015 Horatiu Olteanu, Yuri Fedoriw, Diagnostic Challenges in Low-Grade B-Cell Lymphomas, 2016 CAP Annual Meeting, Las Vegas, NV, 09/25/2016 - 09/28/2016 Horatiu Olteanu, Reactive Lymphoid Lesions vs. Low-Grade Lymphomas in Bone Marrow, 2016 CAP

4 / 14 Annual Meeting, Las Vegas, NV, 09/25/2016 - 09/28/2016 Horatiu Olteanu, Advanced Flow Cytometry-Based Diagnostic Hematopathology, 2016 ICCS Annual Meeting, Bonita Springs, FL, 09/30/2016 - 10/04/2016

PEER REVIEWED WORKSHOPS/PRESENTATIONS: National OLTEANU, H., Banerjee, R., Reductive activation of methionine synthase: Purification and characterization of mammalian methionine synthase reductase, FASEB Summer Research Conference "Folic Acid, Vitamin B12 and One Carbon Metabolism", Snowmass, CO, 08/05/2000 - 08/10/2000 OLTEANU, H., Munson, T., Banerjee, R., Effects of common polymorphisms on the activation of methionine synthase by the dual flavoprotein oxidoreductase, methionine synthase reductase, Gordon Research Conference "Enzymes, Coenzymes and Metabolic Pathways", Meriden, NH, 07/20/2002 - 07/27/2002 Rathke, S., Harrington, A., OLTEANU, H., Kroft, S.H., Del Rosario, S., Ho, KC., Rapidly progressive fatal dementia secondary to lymphomatosis cerebri, CAP Annual Meeting, Washington, DC, 10/11/2009 - 10/14/2009

International Zhang, W., Braun, A., Bauman, Z., OLTEANU, H., Banerjee, R., Profiling four homocysteine-related enzymes in the NCI60 human cancer cell lines, HUPO 3rd Annual World Congress, Beijing, 10/25/2004 - 10/27/2004 OLTEANU, H., Karandikar, N.J., McKenna, R.W., Xu, Y., Differential utility of various markers in the flow cytometric detection of paroxysmal nocturnal hemoglobinuria in blood and marrow, USCAP Annual Meeting, Atlanta, GA, 02/11/2006 - 02/17/2006 OLTEANU, H., Wang, HY., Chen, W., McKenna, R.W., Karandikar, NJ., Immunophenotypic identification of high-risk monoclonal gammopathy of undetermined significance, USCAP Annual Meeting, San Diego, CA, 03/23/2007 - 03/30/2007 OLTEANU, H., Karandikar, N.J., Kroft, S.H., Immunophenotypic and Laboratory Findings in CD4(+) Large Granular Lymphocyte , USCAP Annual Meeting, Denver, CO, 03/01/2008 - 03/07/2008 Walters, M.P., OLTEANU, H., Van Tuinen, P. and Kroft, S.H., CD23 expression in plasma cell myeloma is specific for abnormalities of chromosome 11, and is associated with primary plasma cell leukemia in this cytogenetic sub-group, USCAP Annual Meeting, Boston, MA, 03/07/2009 - 03/13/2009 Harrington, A.M., OLTEANU, H. and Kroft, S.H., The specificity of immunophenotypic alterations in blasts in non-acute myeloid disorders, USCAP Annual Meeting, Boston, MA, 03/07/2009 - 03/13/2009 OLTEANU, H., Bredeson, C., Schur, B.C, and Kroft, S.H., Expression of natural killer receptors in T lymphocytes and NK cells post stem cell transplantation, USCAP Annual Meeting, Boston, MA, 03/07/2009 - 03/13/2009 OLTEANU, H., Harrington, A.M., Kroft, S.H., Plasmacytic neoplasm with plasmablastic features, SH/EAHP 2009 Workshop on the Spectrum of Immunoproliferative Disorders and the Border Between B-Cell Lymphoma and Plasma Cell Neoplasms, Cleveland, OH, 09/24/2009 - 09/26/2009 OLTEANU, H., Harrington, A.M., Kroft, S.H., Lymphoplasmacytic lymphoma with extensive plasmacytic differentiation and plasmablastic morphology, SH/EAHP 2009 Workshop on the Spectrum of Immunoproliferative Disorders and the Border Between B-Cell Lymphoma and Plasma Cell Neoplasms, Cleveland, OH, 09/24/2009 - 09/26/2009 Kroft, S.H., Eshoa, C., OLTEANU, H., Harrington, A.M., Gamma heavy chain , SH/EAHP 2009 Workshop on the Spectrum of Immunoproliferative Disorders and the Border Between B-Cell Lymphoma and Plasma Cell Neoplasms, Cleveland, OH, 09/24/2009 - 09/26/2009 Harrington, A.M., OLTEANU, H., Kroft, S.H., IgM plasma cell myeloma, SH/EAHP 2009 Workshop on the Spectrum of Immunoproliferative Disorders and the Border Between B-Cell Lymphoma and Plasma Cell Neoplasms, Cleveland, OH, 09/24/2009 - 09/26/2009 Harrington, A., OLTEANU, H., Kroft, S.H., Localized bone marrow aplasia following radiation with discrepant peripheral counts, ASCP Annual Meeting, Chicago, IL, 10/28/2009 - 11/01/2009 Randhawa, J.K., Bredeson, C., Fenske, T.F., Saad, A., Palmer, K., Hari, P.N., OLTEANU, H., and Atallah, E., Hypomethylating agent for acute myelogenous leukemia can induce sustained responses with low induction mortality., ASH Annual Meeting, New Orleans, LA, 12/05/2009 - 12/08/2009 OLTEANU, H., Harrington, A.M., George, B., Bredeson, C., Hari, P.N., Kroft, S.H., High prevalence of

5 / 14 Dapsone-induced oxidant hemolysis in North American stem cell transplant recipients without glucose-6-phosphate-dehydrogenases deficiency, ASH Annual Meeting, New Orleans, LA, 12/05/2009 - 12/08/2009 Harrington, A.M., OLTEANU, H. and Kroft, S.H., A Dissection of the CD45/Side Scatter (SS) Blast Gate in Non-acute Myeloid Disorders and Non-neoplastic Bone Marrows, USCAP Annual Meeting, Washington, DC, 03/20/2010 - 03/26/2010 Harrington, A.M., OLTEANU, H. and Kroft, S.H., Incidental, Immunophenotypically Aberrant Cytotoxic T-Cell Clones in Patients with Other Hematologic Malignancies, USCAP Annual Meeting, Washington, DC, 03/20/2010 - 03/26/2010 OLTEANU, H., Schur, B.C, Harrington, A.M. and Kroft, S.H., Time and Temperature Stability of T-Cell Subsets, USCAP Annual Meeting, Washington, DC, 03/20/2010 - 03/26/2010 OLTEANU, H., Harrington, A.M., and Kroft, S.H., The Role of Flow Cytometry in the Diagnosis of Intraocular Lymphoma, USCAP Annual Meeting, Washington, DC, 03/20/2010 - 03/26/2010 OLTEANU, H., Harrington, A.M and Kroft, S.H., CD23(+) Follicular Lymphoma: Immunophenotypic and Clinical Features, USCAP Annual Meeting, Washington, DC, 03/20/2010 - 03/26/2010 Spears, M.D., OLTEANU, H., Kroft, S.H. and Harrington, A.M., Immunophenotypic Stability in Plasma Cell Myeloma by Flow Cytometry, USCAP Annual Meeting, Washington, DC, 03/20/2010 - 03/26/2010 Spears, M.D., Harrington, A.M, Kroft, S.H. and OLTEANU, H., Immunophenotypic Stability of T-Cell Large Granular Lymphocytic Leukemia and Chronic Lympho-proliferative Disorders of NK Cells by Flow Cytometry, USCAP Annual Meeting, Washington, DC, 03/20/2010 - 03/26/2010 Vaughan, J., OLTEANU, H., Wimpee, B., Kroft, S.H. and Jarzembowski, J.A., The Prevalence of Regulatory T-Lymphocytes in Post-Transplant Lymphoproliferative Disorders, USCAP Annual Meeting, Washington, DC, 03/20/2010 - 03/26/2010 Cogbill, C.C., Spears, M.D., Harrington, A.M., OLTEANU, H., and Kroft, S.H., Analysis of Variables Affecting the Flow Cytometric Recovery of Plasma Cell Myeloma Cells in Bone Marrow Aspirates, USCAP Annual Meeting, San Antonio, TX, 02/26/2011 - 03/04/2011 Chang, J.C., Harrington, A.M., OLTEANU, H., and Kroft, S.H., Proliferation Centers in Bone Marrows Involved by Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): A Clinicopathologic Analysis, USCAP Annual Meeting, San Antonio, TX, 02/26/2011 - 03/04/2011 Harrington, A.M., OLTEANU, H., and Kroft, S.H., The Unique Immunophenotype of Double-Hit Lymphomas, USCAP Annual Meeting, San Antonio, TX, 02/26/2011 - 03/04/2011 Horna, P., OLTEANU, H., Kroft, S.H., and Harrington, A.M., Flow Cytometric Analysis of Light Chain Expression Patterns in B-cell Lymphomas Using Monoclonal and Polyclonal Antibodies, USCAP Annual Meeting, San Antonio, TX, 02/26/2011 - 03/04/2011 Schur, B.C., Harrington, A.M., Kroft, S.H., and OLTEANU, H., Lymphocyte Subset Reference Ranges for Evaluation of Immune Reconstitution After Allogeneic Stem Cell Transplantation, USCAP Annual Meeting, San Antonio, TX, 02/26/2011 - 03/04/2011 Buonaccorsi, J.N., Harrington, A.M., Kroft, S.H., and OLTEANU, H., Clinicopathologic Analysis of the Impact of CD23 Expression in Plasma Cell Myeloma with t(11:14)(q13;q32), USCAP Annual Meeting, San Antonio, TX, 02/26/2011 - 03/04/2011 Vaughan, J., Harrington, A.M., Kroft, S.H., and OLTEANU, H., Immunophenotypic Stability of Sezary Cells by Flow Cytometry, USCAP Annual Meeting, San Antonio, TX, 02/26/2011 - 03/04/2011 OLTEANU, H., Harrington, A.M and Kroft, S.H., CD200 Expression in Plasma Cell Myeloma, USCAP Annual Meeting, San Antonio, TX, 02/26/2011 - 03/04/2011 Rathke, S., OLTEANU, H., Kroft, S.H., and Harrington, A.M., CD45 Expression in Plasma Cell Myeloma: Comparison of Flow Cytometry and and Relationship to Prognostic Factors, USCAP Annual Meeting, San Antonio, TX, 02/26/2011 - 03/04/2011 Harrington, A.M., OLTEANU, H., and Kroft, S.H., Most Diffuse Large B-Cell Lymphomas Are Identified by Flow Cytometry, 2012 USCAP Annual Meeting, Vancouver, BC, Canada, 03/17/2012 - 03/23/2012 Parsons, L.N., OLTEANU, H., Kroft, S.H., and Harrington, A.M., Megakaryocytic Associated with Granulocyte-Colony Stimulating Factor, 2012 USCAP Annual Meeting, Vancouver, BC, Canada, 03/17/2012 - 03/23/2012 Vaughan, J., OLTEANU, H., Kroft, S.H., and Harrington, A.M., Flow Cytometric Blast Immunophenotype in Acute Myeloid Arising from Non-Acute Myeloid Disorders, 2012 USCAP Annual Meeting, Vancouver, BC, Canada, 03/17/2012 - 03/23/2012 OLTEANU, H., Harrington, A.M., and Kroft, S.H., CD200 Expression in Non-Myeloma Immunoproliferative Disorders, 2012 USCAP Annual Meeting, Vancouver, BC, Canada, 03/17/2012 - 03/23/2012

6 / 14 Rathke, S.K., OLTEANU, H., Kroft, S.H., and Harrington, A.M., Morphologic Changes in Treated with Hypomethylating Agents, 2012 USCAP Annual Meeting, Vancouver, BC, Canada, 03/17/2012 - 03/23/2012 Horna, P., Kroft, S.H., Harrington, A.M., and OLTEANU, H., Persistence of Residual Normal Peripheral Blood B Cells in Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Identifies a Good Prognostic Subgroup, 2012 USCAP Annual Meeting, Vancouver, BC, Canada, 03/17/2012 - 03/23/2012 OLTEANU, H., Harrington, A.M., Kroft, S.H., Karandikar, N.J., and Fuda, F.F., The Prevalence of CD56 Expression by Flow Cytometry in Acute Promyelocytic Leukemia Patients Treated with All-Trans Retinoic Acid and Anthracycline Drug Combinations, 2012 USCAP Annual Meeting, Vancouver, BC, Canada, 03/17/2012 - 03/23/2012 Vaughan, J., OLTEANU, H., Kroft, S.H., and Harrington, A.M., Blast Immunophenotypes by Flow Cytometry in with Myelodysplasia-Related Changes, 2012 USCAP Annual Meeting, Vancouver, BC, Canada, 03/17/2012 - 03/23/2012 Vaughan, J., Kroft, S.H., OLTEANU, H., Hess, M.A., Miller, R., Harrington, A.M., A Retrospective Analysis of the Utility of Pathology Review Criteria for Peripheral Blood and Body Fluids: One Institution's Experience, ASCP Annual Meeting, Boston, MA, 10/31/2012 - 11/03/2012 Rathke, S.K., Chang, J.C., Harrington, A.M., OLTEANU, H., and Kroft, S.H., The Immunophenotype of Prolymphocytoid Transformation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Revisited, 2013 USCAP Annual Meeting, Baltimore, MD, 03/02/2013 - 03/08/2013 Schumann, J., Harrington, A.M., Kroft, S.H., and OLTEANU, H., NK Cell Reference Ranges Established by Flow Cytometry in Reactive and Lymphomatous Lymph Nodes, 2013 USCAP Annual Meeting, Baltimore, MD, 03/02/2013 - 03/08/2013 Vaughan, J., Mackinnon, A.C., Harrington, A.M., Kroft, S.H., and OLTEANU, H., CD200 Expression in Post-Transplant Lymphoproliferative Disorders Correlates With an Increased Frequency of FoxP3(+) Regulatory T-Cells, 2013 USCAP Annual Meeting, Baltimore, MD, 03/02/2013 - 03/08/2013 Rathke, S.K., Harrington, A.M., OLTEANU, H., and Kroft, S.H., Dim CD33 Expression in Myelomonocytic Marrow Elements: A Novel Description of an Apparently Normal Variant, 2013 USCAP Annual Meeting, Baltimore, MD, 03/02/2013 - 02/08/2013 Hintzke, M., Fenske, T., Kroft, S.H., OLTEANU, H., and Harrington, A.M., CD30 Expression in Non-Hodgkin B-cell Lymphoma, 2013 USCAP Annual Meeting, Baltimore, MD, 03/02/2013 - 03/08/2013 Vaughan, J., Fuda, F., Harrington, A.M., Kroft, S.H., and OLTEANU, H., Immunophenotypic Analysis of Mycosis Fungoides in Large Cell Transformation, ASCP Annual Meeting, Chicago, IL, 09/18/2013 - 09/21/2013 Li, H., Kroft, S.H., Harrington, A.M., and OLTEANU, H., Pure Erythroid Leukemia Evolving from Chronic Myeloid Noeplasms: A Report of 3 Cases, 2014 USCAP Annual Meeting, San Diego, CA, 03/01/2014 - 03/07/2014 Ordobazari, A., Kroft, S.H., OLTEANU, H., and Harrington, A.M., A Comparison of Therapy-Related and De Novo Chronic Myelomonocytic Leukemia, 2014 USCAP Annual Meeting, San Diego, CA, 03/01/2014 - 03/07/2014 Hintzke, M., OLTEANU, H., Kroft, S.H., and Harrington, A.M., Sensitivity and Specificity of Peripheral Blood Findings in Screening for Myelodysplastic Syndrome, 2014 ASCP Annual Meeting, Tampa, FL, 10/08/2014 - 10/10/2014 Batdorf, B., Kroft, S.H., Hosking, P., Harrington, A.M., and OLTEANU, H., Evaluation of CD43 Expression in Non-Hematologic Malignancies, 2014 ASCP Annual Meeting, Tampa, FL, 10/08/2014 - 10/10/2014 Merzianu, M., Cheney, R., Groman, A., Deeb, G., Wilding, G., Cotta, C., Amre, R., Balasubramanian, M., Brandao, G., Brynes, R.K., Cherian, S., Courville, E., Czuchlewski, D., Fan, G., Grier, D., Hoehn, D., Hutchison, R.E., Inamdar, K.V., Juskevicius, R., Kaur, P., Lazarchick, J., Lewis, M.R., Miles, R.R., Myers, J.B., Nasr, M, Naushad, H., OLTEANU, H., Orazi, A., Reddy, V.V.B., Robu, V.G., Salaru, G., Teruya-Feldstein, J., Vajpayee, N., Vos, J., Zhang, L., Zhang, S., Sedelmeyer, A.V., Arguello, V., Aye, L., Barouk, S., Brega, E.F., Carpenter II, R., Coad, J.E., DiPonio, A., Garcia, F., Grantham, J., Ivelja, S., McKenna, R., Sultan, K., Thomsen, M.B., Xu, J., Peterson, L., and Neppalli, V.T., Bone Marrow Core Biopsy Adequacy and Variability in the United Stated and Canada: A Multicenter Retrospective Study, 56th ASH Annual Meeting, San Francisco, CA, 12/06/2014 - 12/09/2014 Gomez-Gelvez, J.C., Fedoriw, Y., OLTEANU, H., Shao, L., and Smith, L.B., Novel morphologic finding and clinicopathologic features of acute myeloid leukemias and myelodysplastic syndromes with isolated

7 / 14 trisomy 11, 2015 USCAP Annual Meeting, Boston, MA, 03/21/2015 - 03/27/2015 Li, H., Kroft, S.H., Hosking, P., Harrington, A.M., and OLTEANU, H., CD38 Expression in Follicular Lymphoma Correlates with Histologic Grade, 2015 USCAP Annual Meeting, Boston, MA, 03/21/2015 - 03/27/2015 Harrington, A.M., OLTEANU, H., Hosking, P., and Kroft, S.H., Unique Aberrant Myeloblast Immunophenotype Associated with Azathioprine Therapy, 2015 USCAP Annual Meeting, Boston, MA, 03/21/2015 - 03/27/2015 Hartley, C., Hintzke, M., Vaughan, J., Hosking, P., Harrington, A.M., Kroft, S.H., and OLTEANU, H., CD30 Expression in Post-Transplant Lymphoproliferative Disorders, 2015 USCAP Annual Meeting, Boston, MA, 03/21/2015 - 03/27/2015 Robin, A., Kroft, S.H., Harrington, A.M., Hosking, P., and OLTEANU, H., Evaluation of Proliferation Index in Lymph Nodes with CLL/SLL, 2015 USCAP Annual Meeting, Boston, MA, 03/21/2015 - 03/27/2015 Harrington, A.M., Shewmake, A.C., Hosking, P., OLTEANU, H., and Kroft, S.H., CD3 Staining on Myeloid Elements in Acute Myeloid Leukemia Bone Marrows, 2015 USCAP Annual Meeting, Boston, MA, 03/21/2015 - 03/27/2015 Hintzke, M., Hosking, P., OLTEANU, H., Harrington, A.M., and Kroft, S.H., Bone Marrow Monocytosis: A Survey of 150 Cases, 2015 ASCP Annual Meeting, Long Beach, CA, 10/28/2015 - 10/30/2015 Schelling, L., Ordobazari, A., Kroft, S.H., OLTEANU, H., Hosking, P., and Harrington, A.M., Immunophenotypic Comparison of Dysplastic and Proliferative Subtypes of Chronic Myelomonocytic Leukemia by Flow Cytometry, 2015 ASCP Annual Meeting, Long Beach, CA, 10/28/2015 - 10/30/2015 Harrington, A.M., Hosking, P., OLTEANU, H., Hamadani, M., Kroft, S.H., Donor-Derived Post-Transplant Lymphoproliferative Disorder following Stem Cell Transplantation, SH/EAHP 2015 Workshop on Immunodeficiency and Dysregulation, Long Beach, CA, 10/29/2015 - 10/31/2015 Batdorf, B., Hosking, P., Harrington, A.M., Kroft, S.H., OLTEANU, H., Monomorphic B-cell PTLD, Burkitt lymphoma, SH/EAHP 2015 Workshop on Immunodeficiency and Dysregulation, Long Beach, CA, 10/29/2015 - 10/31/2015 Robin, A., Hosking, P., Harrington, A.M., Kroft, S.H., OLTEANU, H., Monomorphic T-cell PTLD, Anaplastic large cell lymphoma, ALK(-),, SH/EAHP 2015 Workshop on Immunodeficiency and Dysregulation, Long Beach, CA, 10/29/2015 - 10/31/2015 Mboko, W.P., Tarakanova, V.L., Hosking, P., Harrington, A.M., Kroft, S.H., OLTEANU, H., Tumor Suppressor IRF-1 Expression is Decreased in Post-Transplant Lymphoproliferative Disorders, 2016 USCAP Annual Meeting, Seattle, WA, 03/12/2016 - 03/18/2016 Merzianu, M., Cheney, R., Groman, A., Deeb, G., Wilding, G., Cotta, C., Amre, R., Balasubramanian, M., Brandao, G., Brynes, R.K., Cherian, S., Courville, E., Czuchlewski, D., Fan, G., Grier, D., Hoehn, D., Hutchison, R.E., Inamdar, K.V., Juskevicius, R., Kaur, P., Lazarchick, J., Lewis, M.R., Miles, R.R., Myers, J.B., Nasr, M, Naushad, H., OLTEANU, H., Orazi, A., Reddy, V.V.B., Robu, V.G., Salaru, G., Teruya-Feldstein, J., Vajpayee, N., Vos, J., Zhang, L., Zhang, S., Sedelmeyer, A.V., Arguello, V., Aye, L., Barouk, S., Brega, E.F., Carpenter II, R., Coad, J.E., DiPonio, A., Garcia, F., Grantham, J., Ivelja, S., McKenna, R., Sultan, K., Thomsen, M.B., Xu, J., Peterson, L., and Neppalli, V.T., Variability and Adequacy of Evaluable Marrow Space Length (EMSL) in Bone Marrow Biopsies: A Multi-institutional Study, 2016 USCAP Annual Meeting, Seattle, WA, 03/12/2016 - 03/18/2016 Batdorf, B., Gheorghe, G., Kroft, S.H., Harrington, A.M., OLTEANU, H., Hosking, P., Correlation of CD79a Expression with Additional B-Cell Markers and Bruton's Tyrosine Kinase Expression in T-Cell Lymphoblastic Leukemia/Lymphoma, 2016 USCAP Annual Meeting, Seattle, WA, 03/12/2016 - 03/18/2016 OLTEANU, H., Hosking, P., Harrington, A.M., Kroft, S.H., PD-L1 Expression Correlates with EBV Status in Post-Transplant Lymphoproliferative Disorders, 2016 USCAP Annual Meeting, Seattle, WA, 03/12/2016 - 03/18/2016 Merzianu, M., Cheney, R., Groman, A., Deeb, G., Wilding, G., Cotta, C., Amre, R., Balasubramanian, M., Brandao, G., Brynes, R.K., Cherian, S., Courville, E., Czuchlewski, D., Fan, G., Grier, D., Hoehn, D., Hutchison, R.E., Inamdar, K.V., Juskevicius, R., Kaur, P., Lazarchick, J., Lewis, M.R., Miles, R.R., Myers, J.B., Nasr, M, Naushad, H., OLTEANU, H., Orazi, A., Reddy, V.V.B., Robu, V.G., Salaru, G., Teruya-Feldstein, J., Vajpayee, N., Vos, J., Zhang, L., Zhang, S., Sedelmeyer, A.V., Arguello, V., Aye, L., Barouk, S., Brega, E.F., Carpenter II, R., Coad, J.E., DiPonio, A., Garcia, F., Grantham, J., Ivelja, S., McKenna, R., Sultan, K., Thomsen, M.B., Xu, J., Peterson, L., and Neppalli, V.T., Bone Marrow

8 / 14 Biopsy Practice and Quality Trends in USA and Canada: A Retrospective Multicenter Study, 2016 USCAP Annual Meeting, Seattle, WA, 03/12/2016 - 03/18/2016 Haque, J., Lu, Z., Raj, R., Cockerham, L., OLTEANU, H., Huang, A., Abidi, M., Hari, P., Reactivation of Pulmonary Tuberculosis after Use of Ruxolitib for Myelofibrosis, AMMI Canada – CACMID Annual Conference, Vancouver, BC, 03/30/2016 - 04/02/2016 Hosking, P.R., Kroft, S.H. OLTEANU, H., Harrington, A.M., A patient with a mediastinal mass with features of primary mediastinal B-cell lymphoma and an aggressive clinical course, SH/EAHP 2016 Lymphoma Workshop, Basel, Switzerland, 09/03/2016 - 09/08/2016 OLTEANU, H., Hosking, P.H., Hintzke, M.H., "Double-Hit" Diffuse Large B-cell Lymphoma With t(2;8), t(14;18) And Extensive , SH/EAHP 2016 Lymphoma Workshop, Basel, Switzerland, 09/03/2016 - 09/08/2016

COMMITTEE SERVICE: Medical College 01/2008 Member, Internal review team, MCWAH Hematology/Oncology Fellowship Program, Medical College of Wisconsin 01/2011 - Present Member, IRB Committee #4, Medical College of Wisconsin / Froedtert Hospital 01/2011 - Present Member, MCW Cancer Center, Medical College of Wisconsin 06/2011 Member, Faculty Climate Focus Group, Medical College of Wisconsin 07/2011 - 06/2014 Member, Continuing Medical Education, MCW Faculty Council, Medical College of Wisconsin 10/2012 - 11/2012 Member, Internal review team, MCWAH - St. Joseph's Residency Program, Medical College of Wisconsin 05/2013 - 06/2013 Member, Hematopathology faculty search committee, Pathology, Medical College of Wisconsin 06/2014 - Present Ad hoc Member, IRB Committee #2, Medical College of Wisconsin / Froedtert Hospital 06/2015 - Present Member, Continuing Medical Education Committee, MCW Faculty Council, Medical College of Wisconsin

MEDICAL COLLEGE TEACHING ACTIVITIES: Community/Lay Public 12/2008 - 01/2009 UW-Milwaukee Pre-Med School Mentoring Program (3 hours)

Medical Student Education 01/2009 MCW M2 Pathology Course (2 hours of lectures) 01/2010 MCW M2 Pathology Course (4 hours of lectures) 01/2011 MCW M2 Pathology Course (4 hours of lectures) 01/2012 Myeloid Neoplasms TBL (4 hours) 01/2012 MCW M2 Pathology Course (4 hours of lectures) 01/2013 - 12/2013 M2 Pathology Course (4 hours of lectures), Introduction to WBC Disorders, Reactive and Neoplastic Myeloid Processes, Targeted Leukemia Therapy (4 hours of TBL activity) 01/2014 - 12/2014 Introduction to WBC Disorders, Reactive and Neoplastic Myeloid Processes, Targeted Leukemia Therapy (4 hours of lectures and TBL activity) 01/2015 - 12/2015 Introduction to WBC Disorders, Reactive and Neoplastic Myeloid Processes, Targeted Leukemia Therapy (4 hours of lectures and TBL activity)

Resident and Fellow Education 07/2008 - 06/2009 Pathology reviews and updates (7 hours of lectures) 07/2009 - 06/2010 Pathology reviews and updates (12 hours of lectures) 07/2010 - 06/2011 Pathology reviews and updates (10 hours of lectures) 07/2011 - 06/2012 Pathology reviews and updates (7 hours of lectures) 07/2012 - 06/2013 Pathology reviews and updates (10 hours of lectures) 07/2013 - 06/2014 Pathology reviews and updates (8 hours of lectures) 07/2014 - 06/2015 Pathology reviews and updates (10 hours of lectures) 07/2015 - 06/2016 Pathology reviews and updates (12 hours of lectures)

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EXTRAMURAL TEACHING: Medical Student Education 09/2006 - 11/2006 University of Texas Southwestern Medical Center, Small group discussion leader, Sophomore Pathology Course (6 hours) 03/2007 - 05/2007 University of Texas Southwestern Medical Center, Small group discussion leader, Sophomore Pathology Course (6 hours)

Graduate Student Education 01/1999 - 05/1999 University of Nebraska - Lincoln, Teaching assistant, Biochemistry 433/833 01/2001 - 05/2001 University of Nebraska - Lincoln, Teaching assistant, Biochemistry 433/833 09/2001 - 05/2002 University of Nebraska - Lincoln, Fellow, Preparing Future Faculty

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED: Medical Students Isaac Lloyd, Medical College of Wisconsin, 10/2010 - 06/2011 Pathway mentor. Joseph J. Schumann, Medical College of Wisconsin, 10/2010 - 06/2012 Pathway research mentor. Project: Flow cytometric evaluation of NK cells in tissue specimens. Halle E. Foss, Medical College of Wisconsin, 10/2015 - Present Pathway research mentor. Project: Incidence and Diagnostic Specificity of Dutcher Bodies in Orbital Biopsies. Kort R. Knous, Medical College of Wisconsin, 12/2015 - Present Global Health Scholarly Pathway Advisor and research mentor. • Project: PD-L1 Expression in Post-Transplant Lymphoproliferative Disorders

Clinical/Research Fellows Michael D. Spears, MD, Medical College of Wisconsin, 07/2008 - 06/2009 Research mentor. Project: Immunophenotypic stability of T-cell large granular lymphocytic leukemia and chronic lymphoproliferative disorder of NK cells by flow cytometry Pedro Horna, MD, Medical College of Wisconsin, 07/2010 - 06/2011 Research mentor. Project: Flow cytometric quantitation of normal residual circulating B-cells in patients with chronic lymphocytic leukemia - Clinicopathologic correlations James Vaughan, MD, Medical College of Wisconsin, 07/2011 - 06/2012 Research mentor. Project: Immunophenotypic profile of large cell transformation in mycosis fungoides James Vaughan, MD, Medical College of Wisconsin, 07/2011 - 06/2012 Research mentor. Project: CD200 expression in post-transplant lymphoproliferative disorders correlates with an increased frequency of FoxP3(+) regulatory T-cells James Vaughan, MD, Medical College of Wisconsin, 11/2011 - 06/2012 Research mentor. Project: Establishment of a tissue microarray of post-transplant lymphoproliferative disorders for biomarker discovery Anastasia Drobysheva, MD, Medical College of Wisconsin, 05/2013 Visiting fellow mentor Lindsay Schelling, MD, Medical College of Wisconsin, 07/2014 - 06/2015 Research mentor. Project: Peripheral T-cell Lymphoma, NOS with Germinal Center Phenotype. Maria Hintzke, MD, MCW, 07/2015 - 12/2015 Research mentor. Project: “Double Hit” Diffuse Large B-cell Lymphoma with t(2;8), t(14;18), and Extensive Necrosis

Residents James Vaughan, MD, Medical College of Wisconsin, 07/2009 - 06/2010 Research mentor. Project: The prevalence of regulatory T-lymphocytes in post-transplant lymphoproliferative disorders James Vaughan, MD, Medical College of Wisconsin, 07/2010 - 06/2011 Research mentor. Project: Immunophenotypic stability of Sezary cells by flow cytometry J. Noelle Buonaccorsi, MD, Medical College of Wisconsin, 07/2010 - 06/2011 Research mentor. Project: Clinicopathologic analysis of the impact of CD23 expression in plasma cell myeloma with t(11:14)(q13;q32) Lauren N. Parsons, MD, Medical College of Wisconsin, 07/2012 - 10/2014 Research mentor. Project: Flow cytometric analysis of CD23 and FMC-7 expression in diffuse large B-cell lymphoma

10 / 14 Hongmei Li, MD, PhD, Medical College of Wisconsin, 07/2013 - 06/2015 Research mentor. Project: Pathophysiologic implications of CD38 expression in follicular lymphoma. Hongmei Li, MD, PhD, Medical College of Wisconsin, 07/2013 - 04/2016 Research mentor. Project: Clinical and pathologic features of pure erythroid leukemia evolving from chronic myeloid neoplasms. Bjorn Batdorf, MD, Medical College of Wisconsin, 07/2013 - 06/2016 Research mentor. Project: Evaluation of CD43 expression in tissue microarrays of non-hematologic neoplasms. Adam Robin, MD, Medical College of Wisconsin, 07/2014 - 06/2016 Research mentor. Project: Proliferative rate in chronic lymphocytic leukemia/small lymphocytic lymphoma - clinicopathologic correlations. Christopher Hartley, MD, Medical College of Wisconsin, 07/2014 - 06/2016 Research mentor. Project: CD30 expression in post-transplant lymphoproliferative disorders. Adam Robin, MD, Medical College of Wisconsin, 01/2015 - 10/2015 Research mentor. Project: Monomorphic T-cell PTLD, Anaplastic large cell lymphoma, ALK(-). Bjorn Batdorf, MD, Medical College of Wisconsin, 01/2015 - 10/2015 Research mentor. Project: Monomorphic B-cell PTLD, Burkitt lymphoma.

PEER REVIEWED EDUCATIONAL PRODUCTS: 01/2011 - Present OLTEANU, H.: 320 multiple choice questions contributed to ASCP’s Pathologist Recertification Individualized Self-Assessment Examination (PRISE). Available from: http://www.ascp.org/prise#tabs-0 08/2013 - Present OLTEANU, H.: Flow cytometric evaluation of natural killer cell-associated receptors (NKRs), International Clinical Cytometry Society web presentation. Available from: http://cytometry.org/public/index.php 09/2014 - Present Li, H. and OLTEANU, H.: Pure Erythroid Leukemia Evolving from Chronic Myeloproliferative Neoplasms, Society for Hematopathology Case of the Quarter web presentation, September 2014. Available from: http://www.sh-eahp.org/knowledge-center/case-of-the-quarter 04/2015 - Present Schelling, L. and OLTEANU, H.: Peripheral T-cell Lymphoma, Not Otherwise Specified with Germinal Center Phenotype, Society for Hematopathology Case of the Quarter web presentation, April 2015. Available from: http://www.sh-eahp.org/knowledge-center/case-of-the-quarter 04/2016 - Present Bradley, K. and OLTEANU, H.: Dapsone prophylaxis, College of American Pathologists HE-B 2016 Educational Activity, April 2016

BIBLIOGRAPHY Refereed Journal Publications/Original Papers 1. OLTEANU, H., Banerjee, R.: Human methionine synthase reductase, a soluble P450 reductase-like dual flavoprotein, is sufficient for NADPH-dependent methionine synthase activation. J Biol Chem. 276 (38): 35558-35563, 2001. 2. OLTEANU, H., Munson, T., Banerjee, R.: Differences in the efficiency of reductive activation of methionine synthase and exogenous electron acceptors between the common polymorphic variants of human methionine synthase reductase. Biochemistry 41 (45): 13378-13385, 2002. 3. OLTEANU, H., Banerjee, R.: Redundancy in the pathway for redox regulation of mammalian methionine synthase: Reductive activation by the dual flavoprotein novel reductase 1. J Biol Chem 278 (40): 38310-38314, 2003. 4. OLTEANU, H., Wolthers, KR., Munro, AW., Scrutton, NS., Banerjee, R.: Kinetic and thermodynamic characterization of the common polymorphic variants of human methionine synthase reductase. Biochemistry 43 (7): 1988-1997, 2004. 5. Waly, M., OLTEANU, H., Banerjee, R., Choi, SW., Mason, JB., Parker, BS., Sukumar, S., Shim, S., Sharma, A., Benzecry, JM., Power-Charnitsky, VA., Deth, RC.: Activation of methionine synthase by insulin-like growth factor-1 and dopamine: A target for neurodevelopmental toxins and thimerosal. Mol Psych 9 (4): 358-370, 2004. 6. Leal, NA., OLTEANU, H., Banerjee, R., Bobik, TA.: Purification and initial characterization of the human ATP:cob(I)alamin adenosyltransferase and its interaction with methionine synthase reductase. J Biol Chem 279 (46): 47536-47542, 2004. 7. Zhang, W., Braun, A., Bauman, Z., OLTEANU, H., Madzelan, P., Banerjee, R.: Expression profiling of homocysteine junction enzymes in the NCI60 panel of human cancer cell lines. Cancer Res 65 (4): 1554-1560, 2005.

11 / 14 8. OLTEANU, H., Gerber, D., Partridge, K., Sarode, R.: Acute hemolytic transfusion reaction secondary to anti-Fy3. Immunohematol 21: 48-52, 2005. 9. OLTEANU, H., Xu, Y.: The use of flow cytometry in diagnosis of paroxysmal nocturnal hemoglobinuria. Lab Med 37 (8): 2-6, 2006. 10. OLTEANU, H., Karandikar, N.J., McKenna, R.W., Xu, Y.: Differential usefulness of various markers in the flow cytometric detection of paroxysmal nocturnal hemoglobinuria in blood and marrow. Am J Clin Pathol 126 (5): 781-788, 2006. 11. Dyszkiewicz-Korpanty, A., OLTEANU, H., Frenkel, E.P., Sarode R.: Clopidogrel Anti-Platelet Effect: An Evaluation by Optical Aggregometry, Impedance Aggregometry, and the Platelet Function Analyzer (PFA-100™). Platelets 9:1-6, 2007. 12. OLTEANU, H., Wang, H., Chen, W., McKenna, R.W., Karandikar, N.J.: Immunophenotypic studies of monoclonal gammopathy of undetermined significance. BMC Clin Pathol 8 (13): 1-9, 2008. 13. OLTEANU, H., Harrington, A., Kroft, S.H.: Sperm in peritoneal fluid from a man with ascites: a case report. Cases Journal 2 (192): 1-3, 2009. 14. OLTEANU, H., Downes, K.A., Patel, J., Praprotnik, D., Sarode, R.: Warfarin does not interfere with lupus anticoagulant detection by dilute Russel's viper venom time. Clin Lab 55 (3-4): 138-142, 2009. 15. Parker, S.M., OLTEANU, H., VanTuinen, P., Lawton, C.A., Schultz, C.J., Christians, K.K., Fenske, T.: Follicular lymphoma transformation to dual translocated Burkitt-like lymphoma: improved disease control associated with . Int J Hematol 90 (5): 616-622, 2009. 16. Spears, M.D., Harrington, A.M., Kroft, S.H., OLTEANU, H.: Immunophenotypic stability of T-cell large granular lymphocytic leukemia by flow cytometry. Br J Haematol, 151 (1): 97-99, 2010. 17. Harrington, A.M., OLTEANU, H., Kroft, S.H.: The specificity of immunophenotypic alterations in blasts in non-acute myeloid disorders. Am J Clin Pathol, 134 (5): 749-761, 2010. 18. OLTEANU, H., Harrington, A.M., Ramirez, S., Kroft, S.H., Hari, P.: Efficacy and safety of long-term ( >7 year) alemtuzumab therapy for refractory T-cell large granular lymphocytic leukemia. Br J Haematol, 150 (4): 480-481, 2010. 19. Harrington, A.M., Currey, A., OLTEANU, H., Kroft, S.H.: Persistent Localized Bone Marrow Aplasia following Radiotherapy with Preserved Peripheral Blood Counts: A Study of 8 Cases. Ann Diagn Pathol 14 (3): 168-172, 2010. 20. OLTEANU, H., Schur, B.C., Atallah, E., Bredeson, C., Kroft, S.H.: Expression of Natural Killer Receptors in T and NK cells: Comparison of Healthy Individuals, Stem Cell Transplant Patients and Chemotherapy Patients. Leuk Lymphoma 51 (3): 481-487, 2010. 21. Morice, W.G., Jevremovic, D., OLTEANU, H., Roden, A., Nowakowski, G., Kroft, S.H., Hanson, C.A., Kurtin, P.J.: Chronic Lymphoproliferative Disorder of Natural Killer Cells: A Distinct Entity with Sub-Types Correlating With Normal Natural Killer Cell Subsets. Leukemia 24 (4): 881-884, 2010. 22. Walters, M., OLTEANU, H., VanTuinen, P., Kroft, S.H.: CD23 expression in plasma cell myeloma is specific for abnormalities of chromosome 11, and is associated with primary plasma cell leukemia in this cytogenetic sub-group. Br J Haematol 149 (2): 292-293, 2010. 23. Plaza, J.A., Ortega, P., Lynott, J., Mullane, M., Kroft, S.H., OLTEANU, H.: CD8-positive primary cutaneous anaplastic large T-cell lymphoma (PCALCL): Case report and review of this unusual variant of PCALCL. Am J Dermatopathol 32 (5): 489-491, 2010. 24. OLTEANU, H., Karandikar, N.J., Eshoa, C., Kroft, S.H.: Laboratory Findings in CD4(+) Large Granular Lymphocytoses. Int J Lab Hematol 32 (1 Pt 1): e9-e16, 2010. 25. OLTEANU, H., Fenske, T.S., Harrington, A.M., Szabo, A., He, P., Kroft, S.H.: CD23 expression in follicular lymphoma: clinicopathologic correlations. Am J Clin Pathol, 135 (1): 46-53, 2011. 26. Torgerson, S.R., OLTEANU, H., Tinguely, M., Fenske, T.S.: Central nervous system Hodgkin lymphoma: case report and review of the literature. J NeuroOncol, 102 (2):329-334, 2011. 27. Harrington, A.M., OLTEANU, H., Eshoa, C., Kroft, S.H.: The Unique Immunophenotype of Double-Hit Lymphomas. Am J Clin Pathol, 135 (4):649-650, 2011. 28. OLTEANU, H., Harrington, A.M., Hari, P., Kroft, S.H.: CD200 expression in plasma cell myeloma. Br J Haematol, 153 (3):408-411, 2011. 29. OLTEANU, H.: Case Study Interpretation - Houston: Case 2. Cytometry B Clin Cytom, 80B (4):258-260, 2011. 30. Spears, M.D., OLTEANU, H., Kroft, S.H., Harrington, A.M.: The immunophenotypic stability of plasma cell myeloma by flow cytometry. Int J Lab Hematol, 33 (5):483-91, 2011. 31. Buonaccorsi, J.B., Kroft, S.H., Harrington, A.M., VanTuinen, P., OLTEANU, H.: Clinicopathologic analysis of the impact of CD23 expression in plasma cell myeloma with t(11;14)(q13;q32). Ann Diagn Pathol,

12 / 14 15 (6):385-388, 2011. 32. Horna, P., OLTEANU, H., Kroft, S.H., Harrington, A.M.: Flow cytometric analysis of surface light chain expression patterns in B-cell lymphomas using monoclonal and polyclonal antibodies. Am J Clin Pathol, 136 (6):954-959, 2011. 33. OLTEANU, H., Harrington, A.M., George, B., Hari, P., Bredeson, C., Kroft, S.H.: High prevalence of Dapsone-induced oxidant hemolysis in North American stem cell transplant recipients without glucose-6-phosphate-dehydrogenase deficiency. Bone Marrow Transplant, 47 (3): 399-403, 2012. 34. Vaughan, J., Harrington, A.M., Hari, P.N., Kroft, S.H., OLTEANU, H.: Immunophenotypic Stability of Sezary Cells by Flow Cytometry: Utility of Flow Cytometry in Assessing Response to and Guiding Alemtuzumab Therapy. Am J Clin Pathol, 137 (3): 403-411, 2012. 35. Harrington, A.M., OLTEANU, H., Kroft, S.H.: A Dissection of the CD45/Side Scatter “Blast Gate”. Am J Clin Pathol, 137 (5): 800-804, 2012. 36. OLTEANU, H., Schur, B.C., Harrington, Kroft, S.H.: Time and temperature stability of T-cell subsets evaluated by a dual-platform method. Am J Blood Res, 2 (2): 128-135, 2012. 37. OLTEANU, H., Harrington, A.M., Kroft, S.H.: CD200 Expression in Plasma Cells of Non-Myeloma Immunoproliferative Disorders: Clinicopathologic Features and Comparison with Plasma Cell Myeloma. Am J Clin Pathol, 136 (6): 867-876, 2012. 38. Cogbill, C.H., Spears, M.D., VanTuinen, P., Harrington, A.M., OLTEANU, H., Kroft, S.H.: Morphologic and Cytogenetic Variables Affect the Flow Cytometric Recovery of Plasma Cell Myeloma Cells in Bone Marrow Aspirates. Int J Lab Hematol, 37 (6): 797-808, 2015. 39. Chang, J.C., Harrington, A.M., OLTEANU, H., VanTuinen, P., Kroft, S.H.: Proliferation Centers in Bone Marrows Involved by Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): A Clinicopathologic Analysis. Ann Diagn Pathol, 2016 (accepted for publication). 40. Mboko, J.P., OLTEANU, H., Ray, A., Darrah, E., Kulinski, J.M., Cui, W., Dittel, B., Gauld, S.B., Tarakanova, V.L.: Tumor suppressor IRF-1 counteracts expansion of germinal centers driven by a cancer-associated gammaherpesvirus. J Virol, 90 (6): 2818-2829, 2015. 41. Li, H., Hasserjian, R.P., Kroft, S.H., Harrington, A.M., Wheaton, S.E., Pildain, A., Ewalt, M.D., Gratzinger, D., Hosking, P., OLTEANU, H.: Pure Erythroid Leukemia and Erythroblastic Sarcoma Evolving from Chronic Myeloid Neoplasms. Am J Clin Pathol, 145 (4): 538-551. 42. OLTEANU, H.: Role of Flow Cytometry in the Diagnosis and Prognosis of Plasma Cell Myeloma. Surg Pathol Clin, 9 (1):101-116, 2016. 43. Harrington, A.M., Schelling, L.A., Ordobazari, A., OLTEANU, H., Hosking, P., Kroft, S.H: Immunophenotypes of Chronic Myelomonocytic Leukemia (CMML) Subtypes by Flow Cytometry: A Comparison of CMML-1 vs. CMML-2, Myeloproliferative vs. Dysplastic, De novo vs. Therapy-related; and CMML-Specific Cytogenetic Risk Subtypes. Am J Clin Pathol, 146 (2): 170-181, 2016. 44. Hari, P., Raj, R., OLTEANU, H.: The Anti-CD38 Antibody Daratumumab Can Induce Sustained Response in Multiply Relapsed Aggressive NK/T-Cell Neoplasm. New Engl J Med, 2016 (accepted for publication). 45. Rowan, D., Logunova, V., VanTuinen, P., OLTEANU, H., Peterson, J.F.: Circulating Breast Carcinoma Cells Mimicking Therapy-Related Acute Myeloid Leukemia: A Potential Cytogenetic and Flow Cytometry Pitfall. Int J Surg Pathol, 2016 (accepted for publication).

Books, Chapters, and Reviews 1. OLTEANU, H.: Aquaporin-mediated water transport in erythrocyte membranes: A comparative NMR study in frog and rainbow trout. MD Graduation Thesis, University of Medicine and Pharmacy, Cluj-Napoca, Romania, 1996. 2. OLTEANU, H., R. Banerjee: Cobalamin-dependent remethylation, in Homocysteine in Health and Disease (R. Carmel, D.W. Jacobsen, eds.), Cambridge University Press: 135-144, 2001. 3. OLTEANU, H., R. Banerjee: Biochemical studies of human methionine synthase reductase, in Chemistry and Biochemistry of Pteridines and Folates (S. Milstien, G. Kapatos, R.A. Levine and B. Shane, eds.), Kluwer Academic Publishers: 537-542, 2002. 4. OLTEANU, H.: Biochemical studies of human methionine synthase reductase. Ph.D. Thesis, University of Nebraska, Lincoln, NE, 2003. 5. OLTEANU, H., Harrington, A.M., Kroft, S.H.: Lymph Nodes (Demos Surgical Pathology Guides), Demos Medical Publishing, New York, 2012. 6. OLTEANU, H.: B-cell lymphoma, Mediastinal, Diffuse and Large, in Encyclopedia of Pathology (H. van

13 / 14 Krieken, ed.; S. Suster, section ed.), Springer Verlag, Berlin-Heidelberg, 2014 (in press). 7. OLTEANU, H.: Castleman disease, Mediastinal, in Encyclopedia of Pathology (H. van Krieken, ed.; S. Suster, section ed.), Springer Verlag, Berlin-Heidelberg, 2014 (in press). 8. OLTEANU, H.: Hodgkin lymphoma, Mediastinal, in Encyclopedia of Pathology (H. van Krieken, ed.; S. Suster, section ed.), Springer Verlag, Berlin-Heidelberg, 2014 (in press). 9. OLTEANU, H.: Mediastinal Anaplastic Large Cell Lymphoma, in Encyclopedia of Pathology (H. van Krieken, ed.; S. Suster, section ed.), Springer Verlag, Berlin-Heidelberg, 2014 (in press). 10. OLTEANU, H.: Mediastinal Mucosa-Associated Lymphoid Tissue Lymphoma, in Encyclopedia of Pathology (H. van Krieken, ed.; S. Suster, section ed.), Springer Verlag, Berlin-Heidelberg, 2014 (in press). 11. OLTEANU, H.: Pleomorphic Lymphoma, Mediastinal, in Encyclopedia of Pathology (H. van Krieken, ed.; S. Suster, section ed.), Springer Verlag, Berlin-Heidelberg, 2014 (in press). 12. OLTEANU, H.: Lymphoblastic Lymphoma/Leukemia, Mediastinal, in Encyclopedia of Pathology (H. van Krieken, ed.; T. Molina, section ed.), Springer Verlag, Berlin-Heidelberg, 2014 (in press).

Editorials, Letters to Editor, Other 1. OLTEANU, H., Harrington, A.M., Kroft, S.H.: Immunophenotypic Stability of CD200 Expression in Plasma Cell Myeloma. Am J Clin Pathol, 137 (6): 1013-1014, 2012. 2. Epperla, N., OLTEANU, H., Hamadani, M.: Think outside the box: Acanthamoeba encephalitis following autologous hematopoietic cell transplantation. Br J Haematol, 2016 (accepted for publication).

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