molecules Article Chemical Composition and Antibacterial Activity of Essential Oils from Ferula L. Species against Methicillin-Resistant Staphylococcus aureus Gulzhakhan A. Utegenova 1,2, Kyler B. Pallister 3, Svetlana V. Kushnarenko 1, Gulmira Özek 4, Temel Özek 4, Karime T. Abidkulova 2, Liliya N. Kirpotina 3, Igor A. Schepetkin 3, Mark T. Quinn 3,* ID and Jovanka M. Voyich 3 1 Institute of Plant Biology and Biotechnology, Almaty 050040, Kazakhstan;
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[email protected] (S.V.K.) 2 Faculty of Biology and Biotechnology, al-Farabi Kazakh National University, Almaty 050040, Kazakhstan;
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[email protected] (L.N.K.);
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[email protected] (J.M.V.) 4 Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, 26470 Eskisehir, Turkey;
[email protected] (G.Ö.);
[email protected] (T.Ö.) * Correspondence:
[email protected]; Tel.: +1-406-994-4707; Fax: +1-406-994-4303 Received: 7 June 2018; Accepted: 8 July 2018; Published: 10 July 2018 Abstract: Essential oils (EOs) were obtained by hydrodistillation of various parts of Ferula ovina (Boiss.) Boiss., Ferula iliensis Krasn. ex. Korovin, and Ferula akitschkensis B. Fedtsch. ex Koso-Pol., collected in the flowering/budding and fruiting stages. Eight samples of EOs isolated from F. ovina and four samples from F. akitsckensis were analyzed by gas chromatography–mass spectrometry (GC-MS). The major constituents of F. ovina EOs were α-pinene (6.9–47.8%), β-pinene (1.5–7.1%), sabinene (0.1–20.5%), β-phellandrene (0–6.5%), trans-verbenol (0.9–7.4%), eremophilene (3.1–12%), and 6Z-2,5,5,10-tetramethyl-undeca-2,6,9-trien-8-one (0–13.7%).