[ CITATION: Sydney Brenner. (Aug. 08, 1980). Sir Hans Adolf Krebs Medal, The Weizmann Institute of Science, Ref. SB/1/2, No. 70458. CSHL Archive Repository. Reproduced for educational purposes only. Fair Use relied upon. ]
TELEGRAM SENT: 8- 8- 80 .
TO: DR . U. LITI'AUER (WEIZMANN INSTITUTE, ISRAEL) .
GRATEFULLY ACCEPT YOUR GENEROUS OFFER . DR . D. SECHER WILL RECEIVE
MEDAL ON MY BEHALF AND WILL HAVE A MESSAGE TO BE READ .
SYDNEY BRENNER . .. 6 AUG 198()
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DR S BRENNER MRC LAB OF MO LECULAR BIOLOGY HILLSROAD CAtv'B RI DGE CB22 CH
ORGAN IZING COM~ I TTEE WISHES TO AWARD YOU THE KREBS MEDAL IN ABSENT I A • Tl IE MQAE E: E: THE MEDAL 11.J ILL BE H.6.NDED OVER TO MEMBER OF } YOUR LABORATORY IF ~RESE~T OR ANY OTHER REPRESENTAT IVE YOU MAY SUGGEST WILL A0 PREC IATE YOU SE~D MESSAGE OF RcSDONSE TO
PAGE 2/ _,, I:::. BE R.c\D BY REC IP IENT ON YOUR BEHALF. SPEEDY RECOVERY . LJ~ I EL L I TT AUER
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... ~ • THE WEf&lAi'\~ fNSTl1UTE OF SOENCE
R EHOVOT · IS RAEL
Prof. Uriel Z. Littouer 1 .K1u,? .r ?x,11x '!:l1 1 !l Heod. Oepcrtmont of Neurobiology ;p11.,.,:n,'1J7 :i;i7nr.in wx,
The Jules J. Mallon :i•o•:i11:i7 :iiinp:i Choir of 8ioc!iemlstry pi,IJ .'l 0?1•1 CV i,y
July 8, 1980 ,,~ Jtl1 1980
Prof. Sydney Brenner MRC Laboratory of Molecular Biology University Medical School Hills Road Cambridge CB2 2QH England
Dear Sydney,
I very much r egret to learn of the continuous trouble you have with your leg. It is indeed a pity that you are unable to come . I have also hoped to induce you to participate in our Neurobiology symposium and discuss with you our recent cloning of cDNA for tubulin r'-"-",.,,f "<.: f / i... .
I wish you a speedy r ecovery and hope to see you soon ~
Best wishes,
Sincerely yours,
Uriel Littauer
cc. Prof. U. Bachrach Prof. N. Sharon
CAB lE AOOP.ESS: WEIZINST (I sreal) : D'j:),:!IJ? JYl'.l PHONE: (05 4 ) 82126; SW ITCHBOARD: (054 1821 1 1-83 11 1 :J1!li,U TELEX : 3193 4 :Op'U f N L} 3 '.
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SYDNEYBRENNER MRC L ABORATORY MOLECULAR BIOLOGY UNIVERS I TY POSTGRADUATE MEOSCH CAMS RI DGE ( U. K. )
~~ I SS ING YOUR T1:/0- PAGE ABSTRACT MOLECULAR GENET JCS OF HIGHER ORGANISMS FESS CLOS ING SESSION PLEASE A I R~-'lAIL EXPRESS FOR BOOK THANKS AL I SA DEVIR SlOCHEMISTRY TELAVIV UNIVERS I TY
817541 PO CB G OSEAGRA(\·1 4 7 LN • ' ' \q'O~ 1 ~l-~ T~ - ~ ~ european journal of biochemistry
Editorial Office: Boulevard de la Constitution, 69 / 054 EJB/FEBS B . 4020 Lieg e CBelgium>
• • Professor Sidney Br enner M. R. C. Laboratory of Molecular Biology Hills Road
GB-CB2- 2QH CAMBRIDGE (Angleterre )
• •
Li ese , February ~th , 1980.
Dear Professor Br enner, 13th FEES Meeti ng
We have j ust read that you will give one of t he plenary lectures at the 13th meet ing of FEBS , in Jerusalem , next August.
I wish to remind you that the European Journal of Biochemistry traditionally offers to publish the plenary lectures given at the opening and closing ceremonies of the FEBS meeting.
Although there is of course no obligati on for you to accept this invitation, it would be a great pleasure and a great honour indeed if you accepted to provide us with your manuscript .
It would be particularly convenient , if you could let us have your manuscript at the time of the FEBS meeting to ensure fast publication of your lecture. If you send i t after the meeting , pl ease sent i t to my personal attention.
Looking f orward to the pleasure of receiving a favour able reply t o our invitat• • i• on.
Your s sincerely,
.. f
Claude Liebecq
Encl. : Instr uctions to Authors
Copies : The General Secr etary, 13th FEBS Meet i ng Pr of. Goodwi n , Pr of. Yomtov , Dr I gloi CL/ ad
Tel. : + 32 C4tl 42 76 44 - Cable address : Febsjournal, Liege ' European Journal of Biochemistry
INSTRUCTIO S TO AUTHORS (1980)
GE 1rRAL For periodicals: . Krebs. H. A. (1961) Bioche111. J. 80. 225-233. Authors should sub1nit 3 copies (preferabl) 2 on light\\eight paper) of their contribution. together \\·ith 3 copies of tables and For hoo/..s: Di;-.on. \11 . & \Vcbb. E. C. (1964) £11:y111es, 2nd cdn. pp. 565 - 567. except h alft_o~c~. figures 10 permit editorial evaluation. For figures. Longn1ans Green & Co .. London. the originals and 2 photocopies are acceptable. Only the orrg1nal ~ copy \\ill be returned to the autho rs in case of revision or rejection. I 'or 11111lti-a11tltor hooks and sy111posia: C'oncisel) \.\ ritten and carefully prepared contributions arc Innes. I. R. & Nickerson. M. ( 1965) in The Pltar111acological Basis easier to edit and lo read: they are always published faster than <~l 1'1terapeutics, 3rd edn (Goodman, L. S. & G iln1an, A .. eds) longer papers. fhis docs not justify the division of a large paper pr. 477-520. MacMillan Company, Ne•v York. into several shorter papers. For papers quoted as ' in the press'. wriucn evidence should It \VOu ld facilitate edi torial evaluation if authors would enclose be rrovidcd that the ma nuscript has been accepted and copies of' reprints of relevant preceding papers in duplicate. the typescript or page proofs should be provided for the referees. Papers 'in preparation· should be mentio ned in the text itself. in ·rypcscripts that arc not concisely \Vr illen o r do nol conforrn parentheses, as ·unpublished \VOrk'; 'personal co1n1nunications' to the conventions of the JOURNAL \viii be returned 10 the authors ~hou ld also be 1nentioncd in the text and evidence should be provided for re\ ision. /\ revised paper will bear the dates of the first and fina l that the person or persons quoted have agreed to publication of versions. If a re\ iscd paper contains a significant amount of nc\v their observations. ·Private co1nmunications' should not be n1adc niatcrial. it "ill be considered as a ne\\. paper. rublic. 1anuscripts should be t)pC\\Titten. rriple-spaced rhrouxho11r R.esponsibilit) for the accuracy of bibliographic rel'crcnccs (including References. AcknO\\ ledge1nents. Footnotes, Table~ and rest\ entirely \Vith the author(s). Legends 10 Figures) i.e. about I cm in bet\\een lines-on s heet~ on separate pages and nu1nbered in of uniform 'i1e. not larger than ISO A 4 (appr. 21 x 30 cm) \\ ith 8. Tables should be typed the order the) appear in the text. using Arabic numerals. They a margin 5-cin \\ ide on the left. ~ should be co1nprehensible \Vithout reference to the text. C'onditions specific to the particular experiments should be stated above the /\RR/\t\Gl·~1l· TT OF Tl-II:: MAi':USCRIPT tables to" hich the) refer and belo"· their headings. Units in" hich I. The jirsr page should bear: the results are expressed should appear at the top of each colunin. a) the title. concise but inforniative: Footnotes should be kept to a minimum. b) the comrletc name(s) of the author(s) '''ith first or middle forcnanie spelt out in full: 9. Figures and graphs should be nlentioncd in the text and all c) the na1ne of the laboratory \vhere the "'ork \\'as carried out. should be numbered. using Arabic nu1nerals a lso. The back of each in the language of the country of origin or in the la nguage in figure should be labelled lightly in soft pencil to sho\v the top of the which the 1nanuscript is \Vrit ten : figure, the autho r(s') na1ne(s) a nd the fij?urc nurnbcr. A brief d) a running title of not niore than 70 tellers including spaces: descriplivc legend. con1prehensi ble \Vit ho ut reference to the text. c) lhc address to •vhich correspondence (i ncluding proofs) should should be provided fo r each fi gure: conditions specific to the be sent ; particular experiment should be stated (brief captions in the figure f) the subdi vision under \\1hich the author(s) v1ish(es) the paper will help the reader); these legends should be typed in sequence at to appear in the Table of Contents (see the Table o f Co ntent ~ of the end of the manuscript, not on the figures. recent volu1nes). Original dra1ri11gs and graphs should be drawn \Vilh Indian ink in clean uniforn1 lines on Bristol board. graph paper, blue tracing 2.. ·rhc second page should list: cloth or coordinate paper. printed in light blue. Their si1c should a) a dcdication - iran) -as a footnote to the citle: rrcfcrably not exceed the size of the typed 1nanuscrip1. Good glossy b) the full ro:,tal address( es) of (all) the author(s). in the language rrints are acceptable. The labelling of all figures \vith lcllcrs. \\'Ords. or chc country. of origin;- nunierals. etc. should be left to the publisher. Therefore. let1cring c) the lisc of abbreviations (see belO\\'): 1nust not be placed on the figure. but instead on a cover sheet of d) the code nun1bcrs of enzymes 1nen1ioned in the text. preceded transparent paper or on a photo- or Xerox-cop). b) the letters F-C (for I:nz) me Co1nmission). Illustrations requiring reproduction as halfrone plates should 3. fach paper -.,hould be preceded by an English S11111111(11·y of be avoided \vhcnever possible. Such photographs should be clean nOl ITIOre than 3 -l "n OfthC length Of the paper: this ITia) be divided gloss) prints in sharp focu and as rich in contrast as possible. into numbered sections. The summary should be intelligible in itself. The) should be trimnied at precise right angles. Scales should be If the paper is \\ritten in French or Gennan. the Fnglish gi,en. C:iood glossy pnnts of half-tone figures should be provided su1nn1ar) ... hould be extended to 5-10° 0 of the length of the paper for the referees. Photocopies are not acceptable. and should provide as niuch factual information as possible. A charge \Viii have lo be made for colour plare.1 and ltalj:ro11e i llu.1r ra rions. -l. The /11rroduc1io11 should be brief and should state the the same fie ld. f)Urpose or the \\Ork in relation tO Other \.\"Ork in /\BBRL:. VIA T IO S. SYMBOLS. UNITS. ETC. It should not present an extensive revie•v of literature. The JO URNAL \Viii essentially follo\v the rules defined in the 5 . .\l aterials a11d 1\lletftods should provide enough inforn1ation I UP Ac·s Iv! a11ual of Sy1nbols and Ten11i11ology /(Jr Pltysicoche111ical to pcnnit repetiti on of the experi1n cntal work. Q11a111i1ies anti U11 i1s (B utterworths. London. 1973). Sections A F 6. The Res11lrs should be given concisely. Tables and Figures and l-1 o f' the I UP A C's No n1enclarure oj. Orga11ic Che111istry. 3rd ecln should not illustrate the sanic results. The place where they should ( Perganion Press. Oxford, 1978). I UP A C's Non1e11clar11re
2nd July, 1980.
Profee110r Uriel Bachrach, The Fedeaation of European Biochemical SOcietie•, Israel Biochenical Society, 13th PBBS Meeting, P.O.B. 16271, Tel Aviv, ISRAEL.
Dear Profeaaor Bachrach,
I am sorry to have to write to you to tell you that I will be unable to come to Israel to attend the FEBS Mee&'Pg. The poaition is aa followas last year I had a very serioua fracture my left le9 and up to laat week I was improving well and had already done a small amount of. travelling. Unfortunately it seems that the bones are not properly united and my doctor has advised me not to travel tor the next three months.
I am very sorry if thi• puts you to great inconvenience and am of courae most willinq to foreqo the award of the Krebs medal should your camaittee decide to a.ward it to someone else who could give the lecture.
I hope I have qiven you eno\19h notice ao that you can make other arrangements.
Youra sincerely,
Sydney Brenner.
c.c. Profeasor Uriel z. Littauer, The Weizman.n Institute of Science, Rehovot, Israel. 22 NOV 1979 ~ \ ,. 13th FEBS MEETING THE FEDERATION OF EUROPEAN BIOCHEMICAL SOCIETIES ISRAEL BIOCHEMICAL SOCIETY
JERUSALEM, AUGUST 24-29, 1980 oi1w11· 0 Fl q ~ ' ,.•• u n -....• re a a L November 14, 1979
Prof. Sydney Brenner MRC Laboratory of Molecular Biology University Postgraduate Medical School Cambridge, England
Dear Prof. Brenner: Thank you very much for your cable in which you note the title of the plenary lecture which you are to deliver in the 13th FEBS Meeting. I am sure that your presentation about "Molecular genetics of higher organisms" will be a fitting conclusion to the conference. You should be receiving soon the Second Announcement about this meeting with further details. We look forward to seeing you in Jerusalem. Best regards.
Sincerely yours, M"'~J. ~b..C'-'~ Prof. Uriel Bachrach
UB/gb
Secretariat: 13th FEBS MEETING, P.O.B. 16271, Tel Aviv, Israel . ..
INSTITUTE OF SOENCE ) \D!J REHOVOT · ISRAEL ?x1w, · n1::i1n1
Prof. Uriel Z. Littauer IK1U''7 .T '7K,i1K '!) 1"'\!l Head, Cep11rlmenl of Neuro!liology i"P11?1i::i11iu? ;ip?noi"l wx,
The Jules J. Mallon i"1•oi::i1•::i? ;i,,npi"l Chair of Biochemistry Jl?O .'l 0?1•1 Oil/ ?.v
October 30, 1977
Dr. Sydney Brenner MRC Lab. of Molecular Biology Univ. Postgraduate Med . School Hills Road Cambridge, CB2 . 2QH England
Dear Sydney ,
The Federation of European Biochemical Societies (FEBS) has decided to hold the 13th FEBS Meeting in Jerusalem on August 24- 29, 1 980.
On behalf of the Organizing Committee I have the honor and pleasure to invite you to deliver the Sir Hans Lecture. This plannary lecture will be held at the closing session of the Meeting and also involves the award of the Sir Hans Krebs Medal .
The Sir Hans Krebs Medal and lecture is sponsored by the Lord Rank Center for Research. The previous recipients are M. F . Perutz , A. S. Spirin, D. C. Philips, E. Katchalski , A. B. Pardee, c . Weissman, H. G. Wittmann and F . H. C. Crick.
The Organizing committee will defray your travel as well as your accomo dation expenses and sincerely hopes that you will be able to participate in the 1980 FEBS Mee t ing .
Best wi shes ,
Sincerely yours ,
Uriel Littauer
CAB LE ADDRESS: WE I ZIN S T ( 1sr11 e I) : C 'i' "I J ;J? ) y 7J PH 0 N E: 9 S 1 7 21 : j ~ !:>? O TELEX: 31 9 3 4 : O i'? 1:) THE FEDERATION OF EUROPEAN
BIOCHEMICAL SOCIETIES
JERUSALEM, ISRAEL, AUGUST 24-29, 1980
SECOND ANNOUNeEMENT
ISRAEL BIOCHEMICAL SOCIETY -~ . •
THE 13TH MEETING OF AN INVITATION THE FEDERATION OF EURO PEAN BIOCHEMICAL SOCIETIES The Israel Biochemical Society extends to you a warm Invitation to attend the 13th Meeting of the Federation of European Biochemical Societies, to be held in Jerusalem, Israel, will be held in Jerusalem, Israel, at the August 24-29, 1980. Binyanei Ha'ooma (Convention Center) and the adjoining Jerusalem Hilton Hotel
The program, outlined on the following pages. will Include symposia and colloquia. as well from Sunday, August 24th to Friday, August 29th, 1980, inclusive. as free communications to be presented as posters.
by invitation of In addition to the stimulating scient1f1c program, we believe that we can promise you an The Israel Biochemical Society exciting visit in one of the world's great cities.
HONORARY PRESIDENT E. Katchalski-Katzir N. Sharon U. Bachrach ORGANIZING COMMITTEE For the Organizing Committee N. Sharon, Chairman U. Bachrach, Secretary D. Mirelman, Treasurer R. Arnon Y. Birk U.Z. Littauer A. Tietz-Devir, Poster sessions E. Bachrach, Social actlv1toes
Secretariat : KENES. Clal Center. P.O.B. 983 97 Jaffa St.. Jerusalem. Israel ' Tel. : (02) 222490 - 228553
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Cl) ~ WEDNESDAY AF AUGUST - remain .c a: · - ., I.LI - LL. ., ., 0 s:; · "O < ~(.)~ ~ - N - >- c c -U~ 0 ... c:l ~ TER S-4d FREE .c S·5a .c S·6d S-Sb IX) "' g>al - QCC - - " -CJ) G.I (I) G.I ::> .... • NOON w :J a: l.tJ .c ~ ACTIVITIES ..:: .. G.I 0 > 11> G.I Brea~ by 27 - al - ::E u a: .g - 0 _, !!! ~ Cf) o...: ~ "' >- co 0 ,, 0 0 ~ ~ (ii ::> 0 ~ - .. .. .. - c their c - >. c ,.. c . . UJ -0 () .,, U> .a · "O ~ .c "O c E ~ "' .. CJ) Q. "' :J E ~ " 0 0 .... ~ 0 - · .. - ., - .. ::> - O> ~ 0 >- .. 00 > c - . posters 0 · ,. .c . .'P ~ J: · 0 ::E .. .!! - - .. ' E .. " c .. 0 ... 2" c - .. 0 - 0 I :i I I Coffee Coffee Poster during -b C-8b C-2b C·Sa C-7b C·Sb AUGUST C-7c THURSDAY C · 2c Lunch S-2a S-3b S S S-3c S-5d I N srael Sess -5c + ·2b the ight C·9b C·llb Break C-1 C·8c C·9c Break lunch 28 ions lc • break I I Callee Closing AUGUST FR -- S·3d S·2c S IDAY -S Session e B:ea~ 29 "' SYMPOSIUM 2 S YM P O SI A CELL RECEPTORS AND RECOGNITION SITES SYMPOSIUM 1 Organizers: Z. SELINGER (Israel) and E. HELMREICH (W. Germany) STRUCTURE AND SYNTHESIS OF BIOMEMBRANES I. OHAD (Israel) and L.L.M. VAN DEENEN {The Netherlands) Organozers: S-2a the adenylate 1. Chemical instruments in the study of cAMP and ATP sites of cyclase system. . U.S.S R. S-la E.S SEVERIN, Academy of Sciences of the U.S.S R.. Moscow . 1. Intrinsic protein ~li pid interactions In biomembranes ity of London, London, U.K. brane signalling, D. CHAPMAN, Univers 2. The diverse roles of GTP-regulatory proteins in t ransmem .S.A. M. RODBELL, National Institutes of Health, Bethesda, Md .. U ts. 2. Disposition and mobility of Mycopla1ma membrane componen University of Jerusalem. Jerusalem, Israel adenylate cyclase. S. RAZIN, Hebrew 3. Determining step in the regulatory GTPase cycle of rat pancreatic , Brussels, Belgium L CHRISTOPHE, Free University of Brussels Medical School 3. Topology and dynamics of phosphollpids in membranes. DEENEN, Rljksuniverslteit Utrecht, Utrecht, The Netherlands L.L.M, Van 4. The role of GTP In regulation of adenylate cyclase .activity. Z. SELINGER, Hebrew University of Jerusalem, Jerusalem, Israel S·tb the Semlikl Forest virua membrane. 1. Assembly of S·2b Molecular Biology Laboratory, Heidelberg, W. Germany cGMP formation. K. SIMONS European ,. Effects of a-adrenergic and cholinergic agonlsts on cAMP and G . SCHULTZ, Univers1tat Heidelberg, Heidelberg, W. Germany ic bacteria, 2. Structure and blosynthesia of membranes In photosynthet Albert-Ludwigs-Universltat, Frelburg, W. Germany D. DREWS, 2. The ta·adrenergic receptor from rat liver. J. HANOUNE, HOp1tal Henri Mondor. Cre1e1I, France 3. Assembly of photosynthetic membranes in eukaryotes. of Jerusalem. Jerusalem, Israel I. OHAD, Heb1 ew University 3. Chemical probing of the o-adrenergic receptor. D. ATLAS, Hebrew University of Jerusalem, Jerusalem. Israel S·1c 1. Title to be announced. S-2c York University, New York, N.Y., U.S.A. D.D. SABATINI, New 1. Peptide receptors in cell function and differentiation. G. ROSSELIN, Hopltal Saint-Antoine, Paris, France 2. How mltochondrta import protein• from the cytoplasm. Basel, Switzerland BHK cells. G. SCHATZ. Univers1t8t Basel, 2. Receptors and the control of adenylate cyclase activity in intact G.A, ROBISON, University of Texas, Houston, Tex., U.S.A . membrane: 3. The positioning of sucra1e-lsomalta1e in the Intestinal brush-border plasma membranes. biosy.1 thetic implications. 3. Mitogen receptors and signaling mechanisms in lymphocyte Zurich, Switzerland G. SEMENZA, UniversltAt Zurich, J.C. METCALFE. University of Cambridge, Cambridge, U.K. 4. Protein translocation through biological membranes. A. WAKSMAN, University of Strasbourg, Strasbourg, France -7 - -6- 4 SYMPOSIUM 3 SYMPOSIUM ASPECTS OF IMMUNOLOGY GENE STRUCTURE BIOCHEMICAL Organizers: R. ARNON (Israel) and N. JEANE (Switzerland) Organizers: Y. ALONI (Israel) and H. ZACHAU (W. Germany) S-3a CHROMATIN - STRUCTURE ANO SUPERSTRUCTURE S-4a studies of immunoglobulin fragments. 1. Nucleoaome structure and superstructure in chromatin. 1. Crystallographic Oxford, Oxford, U.K. A KLUG, University Medical School. Cambridge. U.K. O.C. PHILLIPS, University of Probing nucleosome structure. 2. 2. Dynamics aspects of antibody structure and reactivity. National Institutes of Health. Bethesda, Md., U.S.A. G. FELSENFELO, P ZAVOOSZKY. Biological Research Center, Budapest. Hungary 3. Title to be announced. H ZACHAU. Unlversitat Munchen. Munchen, W. Germany 3. Antibodies and somatic cell genetics. C MILSTEIN Un1vers1ty Medical School Cambridge. U.K S-3b ORGANIZATION ANO REARRANGEMENT OF GENETIC MATERIAL 1. Transposable ONA-elements In prokaryotes and eukaryotes. P STARLINGER Univers1tat zu Koln. W Germany S-4b 1. Cellular and molecular requirements of T-B·lymphocyte collaboration. chromosome organiz.-ation and rearrangements 2. ONA sequences involved in F MELCHER$, Basel Institute for Immunology, Basel, Switzerland of genetic material. Academy of Sciences of U.S.S.R., Moscow. U.S.S.R. genes. G.P GEORGIEV. 2 Antigen specific products of lymp'loid cells regulated by immune response . Israel 3. The role of ONA methylation in eukaryotic cells. E MOZES. Weizmann Institute of Science. Rehovot H. CEDAR. Hebrew University, Jerusalem, Israel 3. Antigen receptors on lymphocytes: their role in cell communication. 4. SV-40: a model system for studying gene expression and cell transformation. K EICHMANN, Deutsches Krebs-forschungszentrum, Heidelberg. W. Germony W FIERS. R1JkSun1vers1te11-Gent. Ge11t, Belgium URE ANO EXPRESSION OF EUKARYOTIC GENES S-3c STRUCT S·4c and evolution of several mammallon polypeptide hormone genes. 1. Structure 1. The organization and reorganization of antibody genes. of California. San Francisco. Ca.. US.A. H.M GOODMAN. University P LEDER. National Institutes of Health. Bethesda. Md . U.S A 2. Structuro and e xpression of some chicken genes. and n1ouse. P. CHAMBON, Centre National de la Reche1che Sclenlifique, Strasbourg. Fronce 2. Enunlerntion and organization of immunoglobulin genes in rat I SCHECHTER, Weizmann Institute or Science. Rohovot. Israel 3. Eukaryotic promoter·s. M L. BIRNSTIEL, Un1vers1tat, Zurich, Zurich. Switzerland S-4d OF VIRAL AND EUKARYOTIC GENE CONTROL S-3d MECHANISMS 1. Complete primary structure of a human histocompatibility antigen HLA-B7: The variety of mechanisms for eukaryotic gene control. 1. its evolutionary and func·tionol implications. JR. Rockefeller University, New York, N.Y .. U.S A l .E DARNELL, J L STROMINCER, Harvard Un1vers1ty Cambridge, Mass .. US A RNA 2. Factors involved in the accurate transcription of purified eukaryotic genes by polymerases II and Ill. 2. The genetics and biology of the HLA system. The Netherlands R ROEDER, Washington University School of Medicine. St. Louis. Mo.. U.S A. J J Van ROOD Academ1sch Z1ekenhu1s-Leiden . Leiden and circuloriution of linear DNA: 3. Transcription, splicing, attenuation T lymphocytes. 3. Biochen1ical and functional features of antigen-specific receptors on mechanisms regulating gene expression. H WIGZELL, University or Uppsala. Uppsala, Sweden Y ALONI, Weizmann Institute of Science. Rehovot, Israel -8- -9- SYMPOSIUM 6 SYMPOSIUM 5 DEVELOPMENTAL NEUROBIOLOGY BIOENERGETICS (Israel) and J.P. CHANGEUX (France) Organizers: M AVRON (Israel) and L. ERNSTER (Sweden) Organizers: U Z. LITTAUER S-Sa MITOCHONDRIAL BIOENERGETICS S·6a . junction. 1. Current problems of n1itochondrial energy transduction 1. Regulation of synapse formation in vertebrate neuromuscular L ERNSTER. Un1vers1ty of Stockholm. Stockholm. Sweden J.·P. CHANGEUX, lnstotut Pasteur, Paris. France of the ATPase and of the redox 2. The phenomenological stoichiometries 2. The role of activity in the development of neuromuscular connections. proton pumps. G. VRBOVA, University College, London. U.K. G.F. AZZONE. Un1vcrs1ta d1 Padova, Padova , Italy endplate. 3. Developmental aspects of AChR-channel function in the mammalian B SAKMANN. Karl·Froedroch·Bonhoeffer-lnstotut, Gottongen, W Germany S-Sb MITOCHONDRIAL BIOENERGETICS 1. The electron pathway in the mitochondrial chain. S·6b E.C SLATER. Un1vers1teit van Amsterdam. Amsterdam. The Netherlands 1. Regulation of synapse formation. Structure and function of cytochrome c oxidase. 2. M. NIRENBERG. National Institutes of Health. Bethesda. Md .. US A R. CAPALDI. University of Oregon, Eugene. Or.. U.S A . 2. Gap lunctional communication in developmental neurobiology. 3. The proton pump of cytochrome c oxidase. N. GILULA. Rockefeller University. New York, N.Y .. US A . M WIKSTROM University of Helsinki, Hels1nk1, Finland 10 vivo. 3. Development of cholinergic receptors in brain and their modulation Weizmann Institute of Science. Rehovot. Israel S·Sc MITOCHONDRIAL BIOENERGETICS Y. DUDAI, t . Biogenesis and structure of the ATPase proteolipid. W SEBALD. Gesellschaft fur B1otechnolog1sche Forschung mbH . S-6c in mouse brain. Braunschwe1g·Stockhe1m, W. Germany 1. Ontogeny of muscarinic receptors s. Tel·Av1v University. Tel-Aviv, Israel 2. The study of F, and BF1-ATPase subunits by chemica l modification M. SOKOLOVSKY. France of neurons P.V. VIGNAIS Centre d'Etudes Nucleaires de Grenoble, Grenoble. 2. Nerve growth factors: their role for survival and differentiation 3. The role of the A TPase inhibitor protein in the control of oxidative phosphorylation. during ontogenesis. W. Germany D.H. HARRIS. University of Leeds, Leeds. U.K. H. THOENEN. Max-Planck-lnstitut fur Psychoatrie, Munchen. S·Sd CHOLOROPLAST BIOENERGETICS S-6d during brain and neuroblastoma cell development. I. Following the path of protons in green plant photophosphorylalion. 1. Control of tubulin expression izmann Institute of Science. Rehovot. Israel W. JUNGE. Un1vers1rnt OsnabrOck, Osnabrock, W. Germany U.Z. LITTAUER . We : 100 A proteins. 2. Formation ond hydrolysis of ATP after single turnover light flashes 2. Cell specific expression of cytoskeletol proteins: actin and , Gott1ngen implications for the mechanism of photosynthetic energy coupling. K WEBER. Max-Planck-Institute for Biophysical Chemistry M. BALTSCHEFFSKY. Un1vers1ty of Stockholm. Stockholm, Sweden W. Germany proton translocating ATPase 3. ATP synthesis by a purified photosynthetic 3. Studies on gene expression in developing murlne neuroblastoma. reconstituted into phospholipid vesicles. F GROS. lnstotut Pasteur Pans, France Z . GROMET-ELHANAN. Weizmann Institute of Science, Rehovot, Israel S-6e S-Se CHOLOROPLAST BIOENERGETICS I. Some aspects or the development of the cerebellum. t. Structure, function and biogenesis of proton ATPase. R BALAZS, Institute of Neurology, London, UK. - Israel Institute of Technology. Haifa, Israel development N. NELSON. Technion 2. lntracephalic neural transplants as model systems for the study of phenomena by tho electrical diffuse layer 2. Control of photosynthetic and regeneration in the mammalian CNS. of the thylakoid membrane. at the surface A BJORKLUND. University of Lund, Lund. Sweden , U.K. BARBER. Imperial College of Science and Technology. London . J. 3. Biochemical correlates in developing cerebral cells in culture ture, function .and reconstitution of the chloroplast ATPase complex. 3. Struc E. YAVIN , W eizmann Institute of Science. Rehovot. Israel N. SHAVIT. Ben·Gurion University of the Negev, Beer Sheva. Israel - 11 - - tO- CO LLOQUIUM 2 COLLO Q UI A BIOREGULATION OF ENZYMES COLLOQUIUM 1 Organ12ero S. SHALTIEL (Israel) STRUCTURE AND FUNCTION OF PROTEINS Organizer· I. PECHT {Israel) C-2a 1. Regulation of carbohydrate transport in E. coh. H. KORNBERG. University of Cambridge. Cambridge, UK C·la 1. Conformational flexibility and rigidity and its functional significance 2. Cascade control of glutamine synthetase activity in permeabilized E. coll cells. in several protein molecules. E.R. STADTMAN, National Institutes of Health, Bethesda. Md.. U.S.A. R HUBER, Max-Planck-lnsutut fur B1ochem1e, Munchen. W . Germany 3. M ultimodulation of enzyme activity. 2. Stability of protein structure A . SOLS. Universidad Aut6noma. Madrid, Spain PL. PRIVALOV. Academy of Sciences of the U.S.S.R., Poustch1no, Moscow Region, U.S.S.R. C-2b 3. Correlations between stability and internal flexibility of globular proteins. t. cAMP-dependent protein kinase: structure, function and bloregulation. K. WUTHRICH. Eldgon6ssische Technische Hochschule, Zurich. Switzerland. S. SHAL TIEL, Weizmann Institute of Science, Rehovot. Israel 4. Electrostatic forces and protein conformation: an experin1ental approach. 2. The role of protein phosphorylation in the coordinated control of glycogen A.S. SCHEJTER. Toi-Aviv University, Tel-Aviv, Israel metabolism and fatty acid synthesis. P. COHEN. University of Dundee. Scotland, U.K. C-lb 3. The structure of phosphorylase provides the molecular basis for tho control 1. Structure ,and function of metalloproteins as studied by intrinsic and of glycogen metabolism. extrinsic spectroscopic probes. N. MADSEN. University of Alberta. Edmonton. Canada G ROTILIO, Unlvers1tA Degl1 Studi d1 Roma, Rome. Italy 2. Magnetic and optical spectroscopy of metal ions in the active sites of enzymes. C-2c G NAVON, Tel-Aviv Un1vers1ty. Tel-Aviv, Israel H. HOLZER. Albert-Ludw1gs·Un1vers1tat Fre1burg. W Germany 2. The regulation of the activity and of the synthesis of the enzymes of the 3. Fast reaction studies with multifunctional enzymes. threonine operon in E. coh. I KIRSCHNER Univers1t~t Basel, Basel, Switzerland G.N. COHEN lnsutut Pasteur. Paris, France 3. M olecular basis for specificity of nueleases. C-tc M. KARPEi SKY, Academy of Sciences of U S.S R Moscow U S.S A 4. Enzyme -editing mechanisms in DNA replication and protein synthesis. AR FERSHT. lmperoal College of Science and Technology, London, UK 5. Alloateric transitions in glycogen phosphorylases. H BUC. lnstotut Pasteur. Paros. France - 13- - 12 - COLLOQUIUM 3 COLLOQUIUM 4 INTERFERON COMPLEX CARBOHYDRATES Organizer. M. REVEL (Israel) Organizers: H.M. FLOWERS (Israel) and RC HUGHES (U.K.) C-3a C-4a 1. Generation of distinct molecular species of interferons. 1. The importance of the primary structure of glycoproteins for their metabolism J VILCEK New York Unoversoty New York. N.Y .. U.SA. and function. J. MONTREUIL, Unoversote des Sciences et Techniques de Lotte I, 2. Chemical characterization of interferon. Villeneuve d'Ascq France M . RUBINSTEIN Roche Institute. Nutley. N.J .. U.S.A. and 2. The poly(glycosyl) cha ins of human erythrocyte glycoproteins. Weizmann Institute of Science, Rehovot. Israel T. KRUSIUS. Unoversoty ol Hels1nk1, Helsonko , Finland Biological activities of electrophoretically pure mouse interferon. 3. 3. Complex glycoconjugates of the red cell membrnne ond the chemical basis of Ii E DE MAYER. Fondatoon Curoe - lnstltut du Radium, O rsay. Fra nce specificity. J. KOSCIELAK, lnstytut Hematolog11, Warsaw. Poland 4. Biochomlcal and biological properties of purified murine immune T-interferon. E. FALCOFF, Fondat1on Curie - lnstitut du Radium. Paris. France 4. Structure-function relationships for heparin. U. LINDAHL, Swedish Un1vers1ty of Agricultural Sciences, Uppsala, Sweden C·3b 1. Interferon and the irnmune system. I. GRESSER, Centre Nationa l de la Recherche Scientifique. Villejuif, France C·4b 1. The metabolic role of sialic acid modification. R. SCHAUER, Chnstian-Albrechts·Unovers11at Kiel, Kiel. W . Germany 2. Preparation of human leukocyte interferon for clinical use. K.. CANTELL. Central Public Health Laboratory, Helsinki, Finland 2. The role of dolichyl phosphate in protein glycosylatlon. F W. HEMMING. Unovers1ty of Nottingham. Nottingham UK 3. Human interferon as a therapeutic agent. T.C MERIGAN. Stanford Unoversoty. Stanford, Ca., U.SA. 3. lr>hibition of protein glycosylation and interference with the synthesis of dolichyl(pyro)phosphoryl linked saccharides. RT. SCHWARZ. Justus Loeb1g·Un1vers1tat G1essen. G1essen, W Germany C-3c 1. The action of interferon on retroviruses. A BILLIAU Kathol·eke Un1vers1te1t Leuven. Leuven, Belgium C-4c 1. Transport of lysosomal enzymes by cultured cells. 2. The 2·5A system in interferon - treated and control cells. K. Von FIGURA. Westfalische Wilhelms·Un1vers1tat. Munster, W Germany I KERR. National Institute for Medical Research. London, U.K. 2. A study of cell surface glycoconjugates with N-acetylneuraminic acid-binding 3. The molecular basis of interferon's antiviral and anticellular effects. lectins: wheat germ agglutinin and limulin. M REVEL. Weizmann Institute of Science, Rehovot. Israel M. MONSIGNY. Centre Natoonal de la Recherche Scoentof1que. Orleans, France 3. Lymphocyte lectins and lectin receptors. N. SHARON. Weizmann Institute of Science, Rehovot, Israel 4, Complex carbohydrates involved in cell adhesion. R.C. HUGHES. National Institute for Medical Research, London, U.K. - 14 - - 15 - COLLOQUIUM 5 COLLOQUIUM 7 BIOCHEMISTRY OF AGING ONCOGENIC VIRUSES Organizer D GERSHON (Israel) Organizer: Y. BECKER (Israel) C·Sa 1. Investigation of the nlechanism of age-dependent lipid peroxidation and changes in biological membrane properties. C-7a D. HEGNER, Un1versll&t Munchen, Munchen, W. Germany 1. The transforming genes in avian defective leukemia viruses. 2. Further developments in the membrane hypothesis of aging. D. STEHELIN, lns11tu1 National de la Santa et de la Recherche Med1ca lc, I ZS.-NAGY, University Medical School, Debrecen, Hungary Lille. France 3. Lysosomes and cellular aging. D L KNOOK. REP - Institutes of the Organisation for Heahh Research TNO. 2. Biological and chemical characterization of viral and cellular oncogenes. R11sw1Jk (ZH) The Netherlands J -L. OARLIX Un1vers1te de Genevc Geneve. Switzerland C -Sb . 1. Age-related biochemical changes in neurons of the mammalian CNS ! 3. Title to be announced. M ERM1NI Un1vers11y of Zunch. Zunch. Switzerland R WEINBERG. Massachusetts lnst1tue of Technology. Boston. Mass • US A 2. Posttranstational modifications of some enzymes. J.C. DREYFUS. Universue de Pans, Pans, France 3. The cellular aging of fibroblasts is a biochemical differentiation process C-7b of t'ie fibroblast stem cell system. 1. M olecular biology of enzootic bovine leukosis. K. BAYREUTHER. Unovers1tllt Hohcnhe1m, Stuttgart. W. Germany A. BURNY, Un1vers1te Libre do Bruxelles, Rhode-St.·Genese, Belgium 2. Evolution of avian oncovirusea. COLLOQUIUM 6 J.M. COFFIN. Tufts Univers11y. Boston. Mass .. U.S.A PLASMA LIPOPROTEINS AND LIPOLYTIC ENZYMES 3. SV-40 DNA recombination events. Organizer Y STEIN (Israel) E. WINOCUR. Weizmann Institute of Science Rehovot. Israel C·6a PLASMA LIPOPROTEINS 1. Chemical studies on the structure of high density lipoproteins. W STOFFEL. Un1vcrs1ta1 Koln Koln. W Germany C-7c ONA in transformed and infected cells. 2. Lipoproteins in pathological states. 1. The arrangement of integrated adenov1rus D. SEIDEL. Un1vers1tat Gott1ngen. Gottmgen. W. Germany W DOERFLER, Un1vers1tat zu Koln, Koln. W Germany 3. The metabolic effect of lipid lowering drugs. 2. Molecular organization of herpes viruses. A.I. LEVY. National lnst1tutos of Health. Bethesda. Md. US.A J B. CLEMENTS. Universtty of Glasgow. Glasgow. Scotland, UK C·6b PLASMA LIPOPROTEINS 4. Interactions between apolipoproteil1s and lipids. 3. Intracellular forms of Epstein-Barr virus DNA. J GLOMSET, University ol Washington. Seattle, W ash. . US A. T. LINDAHL. Gothenburg Un1ve1s1ty. Gothenburg. Sweden S. Cellular interactions with lipoproteins. O STEIN. Hebrew University of Jerusalem. Jerusalem, Israel 4. The Epstein-Barr virus and related systems. Round Table Discussion G KLEIN . Karolinska Institute. Stockholm Sweden C.Oc LIPOLYTIC ENZYMES 1. Lipoprotein lipase: what are the rate -limiting factors for its action on lipoproteins? T OLIVECRONA Un1versoty of Umea. Umea. Sweden 2. Lipoproteins in LCAT deficiency. K NORUM University of Oslo Blmdern Norway 3. Interconversion of lipoproteins. S. EISENBERG. Hadassah University Hospital Jerusalem. Israel - 16 - - 17 - COLLOQUIUM 8 COLLOQUIUM 9 GENETIC ENGINEERING CELL FUSION Organizer. I. HERTMAN (Israel) Organizer. A LOYTER (Israel) C-9a C·8a control of membrane fusion. 1. The expression of a cloned rabbit chromosomal ,0-globulin gene in mouse 1. Pharmacological di Padova, Padova, Italy L cells and yeast. A. BRUNI, Un1vers1ta C. WEISSMANN, Un1vers1tat Zurich, Zorich, Switzerland 2. Effect of polyunsaturated fatty acids on fusing viruses. N. Israel Institute for B1olo91cal Research. Nes-Z1ona, Israel 2. The structure and expression of hemoglobin genes. A. KOH A.A. FLAVELL, Un1vers1te1t van Amsterdam Amsterdam. The Netherlands 3. On the mechanism of virus-induced cell fusion. lustus-Lteb1g·Un1vers1t&t G1essen G1essen. W_ Germany 3. Structure and expression of cloned eukaryotic genes. R. ROTI. PH. KOURILSKY lnstitut Pasteur, Paris, France C -9b 1. Incorporation of integral ntembrnne proteins into cell membranes. C ·8b G. EYTAN, Technion·lsrael Institute of Technology. Haifa. Israel 1. Title to be announced. H.W . BOYER. Universuy of California. San Francisco, Ca .. U.S.A. 2. Introduction of foreign phospholipid molecules into the plasma membranes 2. Cloning of Drosophila genes active during embryogenesis. of mammalian cells via vesicle-cell fusion and exe:'1ange. , Md., U SA V. PIRROTTA. European Molecular Biology Laboratory. Heidelberg. W . Germany R.E. PAGANO, Carnegie Institution of Washington, Baltimore interactions between viral 3. Cloning of the histidine operon: structure and regulation. 3. The role of paramyxovirus glycoproteins in the F. BLASI, Centro di Endocrinolo91a e Oncolog1a Spenmentale des C .N A . and cell membranes. ller University. New York. NY.. U.SA. Napoli Italy A. SCHEID. Rockefe 4. Maintenance compatibility and encapcidation of a mini-plasmid derived from prophage-P-1 . C-9c I. HERTMAN, Israel Institute for B1olog1cal Research. Nes·Z1ona, Israel 1. Gor1e expression in normal and transformed cells. J.E. CELIS. Aarhus Un1vers1ty. Aarhus. Denmark of transformation and malignancy in somatic cell hybrids. C·8c 2. Genetic control 1. Molecular and genetic manipulation of Klebsiella nif system. K. WILLECKE, Universltilt Esson - Gesamthochschule, Essen. W . Germany F.C. CANNON, University of Sussex, Brighton, Sussex, U.K. 3. Interaction of cells 1n vitro and 1n v ivo with targeted liposomes. 2. Clothing with cosmids in E. coli and yeast. G. GREGORIADIS, Cl1n1cal Research Centre, Harrow, Middlesex.UK. 8 . HOHN, Fnedrich M1escher-lnstitut, Basel, Switzerland 3. Molecular theory of protein-nucleic acid recognition. R. REIN . Roswell Park Memorial Institute. Buffalo. NY US A - 18 - - t9 - COLLOQUIUM 10 COLLOQUIUM 11 GROWTH AND REPRODUCTION BIOCHEMISTRY IN AGRICULTURE Organizer; A.M. KAYE (Israel) Organizer: Y. BIRK (Israel) C-10a C-1 1a ure. 1. Regula1ion of the cell cycle. 1. Agricultural research and agricult J.A. SMITH. Imperial Cancer Research Fund Laboratories, London. U.K. Y. VAADIA, United States-Israel, Agricultural Research Organization. Ministry of Agriculture, Israel 2. Studies on nerve growth factor mediated arrest of division and neurite growth 2. Effect of nitrogen on t•1e formation of pyrocatechin·humic acid and the in target cells. nitrogen linkage characteristics of this acid. P. CAUSSANO Consiglio Naz1onale delle Ricerche. Rome. Italy H. OZBEK. University of <;:ukurova. Adana Turkey motion in the mechanism of action of insulin 3. Possible role for receptor 3. Steroid hormones and plant growth and development. and epidermal growth factor. J GEUNS. Kathoheke Universite1t te Leuven. Leuven. Belgium J. SCHLESSINGER. Weizmann Institute of Science Rehovot. Israel 4. Protein·flavonoid relations as a biochemical criterion indicative of physiological 4. Gene amplification - selection and growth control. and induced shifts in plant living ocivitles. R.T. SCHIMKE. Stanford University. Stanford. Ca .. U.S.A . U. MARGNA. Institute of Experimental Biology, Harku. Estonian S.S R. , US S.R C·IOb C-11b 1. The role of the polyamines in cell proliferation. 1. Proteinase inhibitors in natural plant protection . 0 . HEBY. Un1vers1ty of Lund, Lund. Sweden C.A. RYAN, Washington State Un1vers1ty. Pullman. Wash .. U.S A. 2. Androgens as regulators of cell growth and cell division. 2. Protein alpha-amylase inhibitots from cereal and other plant species. W .1.P. MAINWARING University of Leeds, Leeds, U.K V. SILANO. lnsututo Superiore do San1ta. Rome. Italy 3. Acquisition and loss of androgen responsiveness in the embryonic mammary 3. Regulation of locust vitellogenesis: implications for control of insect reproduction. gland: role of tissue interaction. SW APPLEBAUM. Hebrew University of Jerusalem. Rehovot. Israel K. KRATOCHWIL, Osterre1ch1sche Akadem1e der W1ssenschalten. Salzburg. 4. An antiviral factor from virus infected plants. Austria I. SELA. Hebrew Un1vers1ty of Jerusalem. Rehovot, Israel C -10c C-11c 1. Controls of meiotic division In Xonopus laev1s oocyte: steroids, membrane, 1. The biosynthesis of nutritionally irnportont amino acids in plants. cAMP and receptors. P.J. LEA. Rothamsted Experimental Station. Harpenden. Herts .. U.K. E. BAULIEU. Un1vcrslte de Paris Sud. Bicetre, France 2. Seeds storage proteins: proteosynt'1esis and deposition into protein bodies 2. Neuroendocrine control of reproduction. during seed maturation. Y. KOCH. Weizmann Institute of Science. Rehovot, Israel J.C. PERNOLLET lnstitut Nauonal de la Recherche Agronom1que . Versailles France 3. Human growth hormone: recent chemical and biological studies. C.H. LI. University of California. San Francisco, Ca .. US A 3. Potential applications of gr'ain protein biochemistry in Brazilian agriculture. E DERBYSHIRE University of Durham. Durham. U.K. 4. The interplay of chromatin replicative processes and hormone action in cell differentiation. 4. Plant polyphenoloxidases and their importance in foods. G.C. MUELLER. Un1vers1ty of W1scons1n, Madison. Wis.• US.A A M MAYER, Hebrew Un1vers1ty of Jerusalem. Jerusalem. Israel -20- - 21 - COLLOQUIUM 12 POSTER SESSIONS NUCLEIC ACIDS - PROTEIN INTERACTIONS Poster sessions will be organized 1n accordance with the topics of the six symposia and twelve colloquia described above. Add1t1onal sess•ons will be arranged for work unrelated Organizer: A. HOCHBERG (Israel) to these topics. Participants who wish to present a poster should supply an abstract typed on the enclosed C·12a abstract production form. Abstracts should be written 1n English and typed according to the 1. Conformation aspects of substrate properties of nucleosides and nuclootldet Instructions given. A letter of acceptance will be malled by May 1980 together with instructions tov1ards various enzymes. for preparing the posters. D. SHUGAR, Academy or Sciences, Warsaw, Poland All abstracts will be printed in the Abstract book together with the summaries or the symposia 2. Nucle.ic acid structure in complex assen1blies. and colloquia lectures. The book will be distributed to participants at the time of registration. C.R. CANTOR, Columbia University. New York, N.Y., U.S A In accordance with the recommendations or the FEBS Council, one author can submit only one abst,.act and be c:o·author of no more than two additional contribulions. 3. Dynamic aspects of aminoacyl ligase-tRNA intercation - some essentials for the recognition process. The deadline for submitting the abstract together with the registration form and registration F. Von Der HAAR, Max-Planck-lnstttut fur Experimentelle Medozln, fee Is March 31st, 1980. Please mail the abstract to Dr. A. T1etz-Devir. Dept of Biochemistry, Gottongen, W. Germany Tel-Aviv Un1vers1ty, Tel Aviv. Israel. Regostrauon forms and fees should be mailed separately to FEBS 1980, P.O. Box 983, Jerusalem. Israel. 4. Tryptophanyl tRNA synthetase-tANA'" interactions. L.l. KISSELEV, Academy or Sciences of U.S.S.R .. Moscow, U.S.S.R. C·12b SATELLITE MEETINGS 1. Structure and function of ribosomes. H.G. WITIMANN. Max-Planck-lnst1tut fur Molekulare Genet1k, Berlin, Several satellite meetings of the 13th FEBS Meeting are planned for either before or aher W. Germany the conference itself. These spec1ahzed meetings are complementary to the program of the conference and provide opportunities for FEBS participants to attend smaller and more 2. Structure and function of rANA. spec1ahzed symposia. Participants 1n tho FEBS Meeting may obtain further 1nformat1on about A . ZAMIA. Weizmann Institute of Science. Aehovot. Israel any of these satellite meetings by contacting the ond1v1dual organizers hsted below The 3. SS and S.8S ribosomal ANA-protein complexes; a model system for nucleic registration for a satellote meeung is to be made through the organizer of that meeting acid-protein interaction studies. V.A. ERDMANN, Max·Plonck-lnstitut fur Molekulare Genet1k, Berlin, W. Germany Arrangements for additional satellite meetings may be made through the Secretary of the 13th FEBS Meeting: Dr. U. Bachrach. Dept. of Molecular Biology. Hebrew Un1vers1ty - 4. New results in the study of ribosomal ANA-protein interaction. Hadassah Medical School, P 0 . Box 1172, Jerusalem , Israel. J.P. EBEL, Centre Nallonal de la Aecherche Scientifique Strasbourg, France C-12c 1. The role of soluble protein factors in the initiation of protein synthesis. M. GRUNBERG-MANAGO. lnstllut de B1ologie Phys1co-Ch1m1que, Pans. France 2. Th e elongation factor EF-Tu. Effects of alterations in the tufA and tulB genes. L. BOSCH. State Un1vers1ty of Leiden, Leiden, The Netherlands 3. Analysis of hamster lens cells transformed by SV-40. H. BLOEMENDAL. University of Nl1megen . Nijmegen, The Netherlands - 23 - - 22 - OF SOCIAL EVENTS BIOCHEMICAL APPROACHES TO ORGANIC SYNTHESIS. PRELIMINARY PROGRAM August 2G-21 , 1980, Jerusalem, Israel. (Part1c1pa11on hm1ted to 120). SUNDAY, AUGUST 24th, 1980 lnforma11on and registration· Or. Leon Goldstein 21.00 Informal Reception given by the Israel B1ochem1cal Society Oepartrr.~nt of Biochemistry at the Blnyanei Ha'ooma Tel-Aviv University Tel Aviv, Israel MONDAY, AUGUST 25th, 1980 THE BIOCHEMISTRY OF PARASITES. 20.30 Reception by the Municipality of Jerusalem at the Israel Museum, August 2G-22, 1980, Jerusalem, Israel. followed by a tour of the Museum Information and registration: Or. Hadar lsserolf TUESDAY, AUGUST 26th, 1980 Department of Biology Evening At leisure: State Un1vers1ty College Tickets to " Sound and Light"' presentation in the Old City of Jerusalem At Buffalo and other cultural events will be offered for sale to participants Buffalo, New York 14222 U.SA. WEDNESDAY. AUGUST 27th, 1980 Or. Gerald M. Slutzky 14.30 The following tours will be offered (1) Tour of Jericho, Qumran Caves. and Sanford F. Kuvin Center Dead Sea (bathing optional): (2) Bethlehem: (3) the Old City of Jerusalem: for the Study of Infectious (4) the New City of Jerusalem and the Hebrew University campus. and Tropical Oiseoscs Hadassah Med1ca I School Evening At leisure The Hebrew University Ein Karem. Jerusalem THURSDAY, AUGUST 28th, 1980 Israel 21.00 Israel Night CONNECTIVE TISSUE MATRIX MACROMOLECULES. August 2G-22, 1980, Jerusalem, Israel. Information and registration : PRELIMINARY PROGRAM FOR ACCOMPANYING PERSONS Or. S. Shoshan Research Lab. Connective Tissue Registered Accompanying Persons are invited 10 all Social Events of the Meeting P.O . Box 1172 In add111on the following program has been prepared for them· Jerusalem. Israel ISMS IN PHOTOSYNTHESIS. CONTROL MECHAN MONDAY. AUGUST 25th, 1980 August 31 - September 4, 1980, Rehovot, Israel. Information and registration: 09.00 Tour of the O ld City of Jerusalem Or. M. Avron 16.00 Israeli Fashion Show Dept. of Biochemistry Weizmann Institute of Science TUESDAY, AUGUST 26th, 1980 Rehovot, Israel 09.00-13.00 Visit to Yad Vashem (Holocaust Memorial), Hadassah Hospital, INTERNATIONAL SYMPOSIUM ON POLYAMINES IN NORMAL ANO the Chagall Windows, and a Kibbutz NEOPLASTIC GROWTH. September 8-9, 1980, Rimlni, Italy WEDNESDAY, AUGUST 27th, 1980 Information and re91strat1on 14 30 The following tours will be offered (1) Tour of Jericho, Qumran Caves, and Prof. C.M. Caldarera Dead Sea (bathing optional), (2) Bethlehem: (3) the Old City of Jerusalem: lstituto d1 Ch1m1ca B1olog1ca or (4) the New City of Jerusalem and the Hebrew University campus University of Bologna via lrner10 48 THURSDAY, AUGUST 28th, 1980 Bologna 40126 09.00 Visit to Arts & Crafts workshops 1n the Old and New City Italy -25- - 24 - GENERAL INFORMATION TRAVEL AND ACCOMMODATIONS PEL TOURS LTD., have been appointed off1c1al travel agents to the Meeting and their network HEADQUARTERS (as listed In this brochure) offers you the best possible travel Blnyanei Ha·ooma (Convention Center), Jerusalem. Tel. (02) 222481 : of offices and agents abroad arrangements to and from Israel. The agents listed In the brochure have been appointed In and the adjoining Jerusalem Hiiton Hotel. Tel. (02) 536151 consultation with the Biochemical Society of each member country. In Israel, Peltours. through hotel accommodation, meet LANGUAGES their head office and branches throughout the country will furnish The official language of the Meeting Is English. participants on arrival, arrange transfer to hotels and provide all the sightseeing tours which may be requested. N REGI STRATIO Hotel accommodation has been reserved In Jerusalem for the period August 24th to 29th In A perforated Registration Form can be found at the end of this Second Announcement. hotels of the following grades: 5-Star, 4·Stsr. 3-Star and 2-Star, and all these rooms will be Please type or write 1n BLOCK LETTERS and mail 11 to "FEBS 1gBO", P.O B. 983. Jerusalem. allotted on a first come first served basis In add1t1on. student dormitories. youth hostels and Israel Early registration would be greatly appreciated as 1t facilitates conference planning. camping facilities may also be available. RECISTRATION FEE (per person) In order to obtain the desired accommodation, please fill 1n the perforated ACCOMMODA· By May 14, 1980 From May 15, 1980 I TION FO'lM, which can be found at the end of this Announcement. and mail 11 directly to O.M OM Peltours Ltd .. P.O . Box 394, Tel Aviv, Israel Participant 225 275 - Christian, Moslem and Jewish - will be organized Young Scientist (under age 30) 125 150 Visits to the historic sites of Jerusalem by Peltours Ltd. Special ararngements have also been made to offer you a post-Meeting Accompanying Person so 50 sightseeing program. For further details, please apply to the Peltours Overseas agent in The fee covers: eeing. hotel accommodation Participation In all Sessions / Receptions / Social Events I Accompanying Persons Special your sroa who will gladly assist you In the arrangements for sights and any o ther requirements in t he field of travel. Program In the event of cancellation. full refund of the registration fee may be obtained up to three months before the Meeting, and 50o/0 of the fee up 10 one month before the Meeting. are the official carriers and their offices throughout the world w1l1 No refund will be made 1f cancella11on 1s receiver after July 21st, 1980. EL AL ISRAEL AIR LI NES be at the service of participants for their flight arrangements BANK PELTOURS LTD. The off1c1al Bank of the Meet1ng is the Bank Leumi Le-Israel BM., K1kar Malche1 Israel Congress Department Branch, Tel Aviv. Israel. Checks or drafts may be made payable to "FESS Israel 1980". Achad Ha'am St. 28 P.O. Box 394 CLIMATE Tel-Aviv, Israel The weather m Jerusalem 1n August is very pleasant a~d sunny during the day and cool in Tel.: 03/650851 the evenings: maximum daytime temperature about 30° C (86 F) and m1n1mum n1ght1me Telex: 03-3803 temperature about 20 C (67 F). No rain 1n August. Cable address: PELTO URS TELAVIV CLOTHING Informal for all occasions - wrap or coat for cool evenings. VISAS Entry visas to Israel are not required from citizens of most countnes In case of doubt, please contact the nearest Israeli Consulate or write directly to the Secretary of the Organizing Committee. If necessary. a visa will be issued upon arrival at the airport 1n Israel. CONGRESS ORGANIZERS Kenes - Organizers of Congresses and Special Events Ltd , P.O Box 983. Jerusalem. Israel CORRESPONDENCE Kenes , Clal Center, P.O . Box 983, 97 Jaffa St . Jerusalem, Israel - 26 - - 27 - Trends in Enzymology Proceedings of the 12th Proceedings of the.: FEUS Spc.:c ial :\lc.: c.: ting FEBS Meeting Dresden 1978 o n Enz ym c.:s Puhlishccl in() \olunic' (:'\o~. 51 56) lndi\'idual \ 'olunH'S 1 Editor: S. Rapo po rt , /11•rfi11, (;f )J<. l Si44.00 1:22.00 Dubrovnik, Ap ri l 1979. z.,·olun1c ~et Six-\ 'olun1e Set General Editor: P. :\lildne r, 1.agre!J 'l'hl' six \'oh11nl'S. i ndudin~ 1heir editor~ 0 08 02:) I G:i 9 l'S~220.00 £ 11 0.00 .incl subjects fo1 di,cu,sion ,1n:: 1782pp 197<) \ 'olu1nl' 60 \ 'ol11111c 5 1 \ 'olun1t• 5+ Editor: P. ~ l il d n c r & B. Ries Editor: S R<>-t· nthal l'l ,ti Editor~: E.-(; Krau,t·, r. Pin na & R e~11l,1tion of l'll/~ inc acti\ ity. En1~ nleS (;cnt• Fun<.:t ion . \ \\'o llcn berger in nucleic .icid .ind protein >ynthc~is 0 08 O'.? :) I ; :i (i C\·clic :\ucleoticlc~ and 1'1ott•i1, l'ho.,phory· Protcol\'tic. en1,,·n1e\. \ 'olun1e 5'.! lation in C«ll Rcg11l,1tion n 08 02:) I 7 8 0 \ 'olumc 6 1 Editor'>: E I loffn1an. E Pfe il & 11 .\ urich Editors: \ '.Simeon & L.J. \ "italc l'rotl'in : Stn1< !lilt', l·unt tion ,111d lndu,tri.il \ 'olurne 55 En.:ymcs in p.irasites. Clinical cn.:ymolol{y. . \pplic,11 ion' Fditor,: :\I f.ucknt·r & K Schn·iht·r En.:,·mcs of 1nd11s1ri,1l interest. 0 08 02:) I 76 I R.-gu lat ion of Second.1r\ Prndur t .ind \ ' o lu inc 5 3 l'l,1nt I lonnont• :\h:taholi.,111 () 08 0231 79 9 o 08 02.i..i.1; 3 Lisi i oo.oo £ -1-5.oo Editor,:S Rapoporl & I !:ichc\\ e 800pp ,1pprox J 9 79 · Proccs,in)( ,1nd I 1tr110\l'r of Protein' ,11Hl \ "o lun1e 56 Organelle, in tltc Ce ll Editors: G. Jacobasch & S Rapoport ~ 0 08 023 I 7 7 2 \lolceular J)iseaSt'S (I) 0 08 023 180 2 (I)..,"' ..,' Prices subject to c hange without not ice. Headington Hill Hall Oxford O XJ OBW UK :::"' PERGAMON PRESS Maxwell House Fairview Park New York I 0523 USA "' Sterling prices apply to customers in U.K. and Eire o nl y. ~ Ci; ------ -i )> -i -u 0 :::> OJ 0 z () z -u en -u Q) Q) . (!) - =r (!) )> 0 0 :0" c (!) (!) :::> 0 c Q) Q) -0 :::> :0 (!) Q) s: (') " en en (/) (/) - "A s: c ~ s: -i "r -i z (!) 0 (!) '< -0 ,,...... m z z OJ )> - )> ...... 3 (/) -i m )> z (!) 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