occasion. Since then his feces have been repeat edly examined for ova without any beingfound. In the second case, a child of four years, four seven-and-a half-grain doses of thymol were administered at hourly intervals. From the two evacuations which followed, 200 worms were picked out. A week later the same doses were re- peated, with the result that only six worms were found. A third repetition of the dosage was not followed by the appearance of any worms. Three weeks after the last dose no ova were discover- ed in the fgeces on microscopical examination. The thymol should be given in powder, capsules or water being used; but alcohol in an}7" form should be prohibited, because the solubilit}?- of thymol in alcohol may lead to absorption and severe toxic symptoms. External use of Salicylic Acid in Rheu- matic Fever. (The Practitioner).?The simple application of an ointment containing salicylic acid to the inflamed joints in rheumatic fever is stated to give good results. The ointment consists of: Salicylic acid, turpentine, and lanolin, of each half an ounce, and lard four ounces. After applying this ointment without friction, the joints are enveloped in flannel. Examination of the urine 24 hours later in several cases showed that from 3 to 14 grains of salicylic acid were eliminated. Salicylate of Methyl. {The Lancet).? Salicylate of methyl, an anti-rheumatic drug and the chief constituent of oil of wintergreen, can be administered by cutaneous absorption (ta[t[citt JPediral J"ifcratiu[f. in a manner similar to guaiacol. In the blood it becomes transformed into salicylate of soda, MEDICINE. and it is eliminated in the urine as salicylic Thymol treatment of Anchylostomiasis. acid. The application is simple. About a By A. Jefferis Turner, m.d. (Intercolonial drachm of the salicylate of methyl is painted on Medical Journal of Australasia.)?After de- the skin, which is then covered with oiled silk scribing the spread of anchylostomiasis in or gutta-percha tissue, over which some cotton Australia, Dr. Turner gives his experience of wool and a bandage are applied. treatment. He had disappointing results with Some uses of Cimicifuga Racemosa. F. R. calomel, santonin, male fern, naphthalin, naph- Millard, m.d. (The Medical and Surgical thol, thymol, and other drugs. Ordinary doses Reporter).?Throughout the article this is spoken " of thymol, such as five grains thrice daily, he had of by the author as black cohosh," which he found utterly useless; but on reading Sonsino's considers a better remedy than arsenic for the treatment of giving as much as six to eight chorea of adolescence, and for the menstrual grammes to an adult in the course of a few irregularities of women. For girls of a rheu- hours, he resolved to another trial. matic diathesis with retarded menstruation and " give thymol Closely following his (Sonsino's) method, I dysmenorrhcea he recommends :?

who had been ...... subjected a boy aged seven years, Potassii Iodidi ... 3^- ??? treated two years before to the Syr. Simplicis ...... Sj"1 unsuccessfully ??? co...... he was on Syr. Sarsaparill? 0iv. routine:?For one ??? following day kept Fl. Extr. Black Cohosh ... 5^ strict milk diet, and an aperient administered. Sig : A until menstruation is The next morning he was given four ten-grain teaspoonful thrice daily regular. doses of thymol at hourly intervals, being allow- Then take it two weeks of each month, begin- ed only water to drink during the intervals. ning ten days before the expected return of the The milk diet was enforced till the evening menses. Continue it each month until men- when the bowels were cleared out by a saline struation is painless. worms were and Medical aperient. In this way a great many Thyroidin Obesity. (The expelled. A week later the same routine was Press and Circular).?Schesinger, of Vienna, repeated, except that four fifteen-grain doses treated a woman weighing 18st. 121bs. with four were given, and this was repeated on a third tabloids of thyroidin daily for thirteen months. 260 INDIAN MEDICAL GAZETTE. i July 1890.

of the is dissolved in about 10 At the end of this time her weight was reduced gramme powder of 33 cent, alcohol in water. The to 13st. 1 libs. In this case, as in others, it was grammes per test solution is now for but found that the thyroid of the ox was not nearly staining ready use; a fresh solution is each because it so efficacious as that of the sheep. required time, Guaiacol as an An/esthetic. {The Medical retains its characteristic staining qualities only a Press and as local anaes- for few hours. Circular).?Guaiacol, " The reaction described consists in thetic, is being employed in France as a substi- peculiar the selective of a certain substance occur- tute for hypodermic injections of cocaine, espe- affinity in red of diabetic for cially in the case of children and people with ring corpuscles patients another substance contained in the colour re- heart disease. For hypodermic injection a solu- a or substance tion of sterilized olive oil, containing ten per cent, agent ; possibly specific principle red blood forms a new of guaiacol, is used. Anaesthesia is produced in in the diabetic corpuscles with one from five to ten minutes, and lasts for about five chemicat compound of the staining in the eosin and twenty minutes. Another method is to principles contained methylene blue solution. At all events the red blood place a compress containing twenty to fifty drops corpuscles or blood are stained of guaiacol, covered with oiled silk, over the part of diabetic glycosuric greenr whereas those of non-diabetic blood a to be operated on, present The Diagnosis of Diabetes from a Drop purple or madder colour." of Blood. By L. Bremer, m.d. {The New D. M. MoiR, M.A., M.B, York Medical Journal).?Dr. Bremer in 1894 published a method of diagnosing diabetes by staining and microscopic examination of the blood; but this method has proved tedious and difficult, so he has devised a much simpler " process by means of which diabetes can be demonstrated almost as readily by a drop of blood obtained from the tip of the fiuger by the prick of a needle as it can be done by the urine tests ordinarily employed." The drop of blood is evenly spread between two cover-glasses, which are then separated and allowed to dry. A similar procedure is adopted with a specimen of non-diabetic blood. A cover- glass preparation of each kind of blood is then put in a wide-mouthed bottle containing equal parts of alcohol and ether. The jar is then put in hot water, and the ether-alcohol is boiled for four minutes, the boiling point being about 60?C. This is done 111 order to fix the haemoglobin in the red corpuscles. The cover slips are now transferred to the test-staining reagent, in which they are kept for four minutes. They are next washed in water. It will then be found that the diabetic or glycosuric blood film presents a sap-green, or sometimes a bluish-green colour. Whereas the non-diabetic blood preparation looks reddish-violet. This difference is very striking, and can be detected by the naked eye without having recourse to a microscope. The staining reagent is thus prepared. Satu- rated watery solutions of eosin and methylene blue are mixed in about equal proportions, so that a neutral point is obtained. A precipitate forms which is insoluble in water, but soluble in alcohol. The precipitate is dried and reduced to a fine powder, and to it are added eosin and methylene blue in small quantities, the amount varying with the relative acidity and alkalinity of the samples of the dyes used. The author has been accustomed to add part of eosin and ? part of methylene blue to the neutral (dried) compound. This yields a powder of a reddish-brown colour. About 0 025 to 0 05