molecules Article In Vivo Wound Healing and In Vitro Anti-Inflammatory Activity Evaluation of Phlomis russeliana Extract Gel Formulations Mehmet Evren Okur 1,*, Ay¸seEsra Karada˘g 2,3 , Neslihan Üstünda˘gOkur 4 , Ya˘gmurÖzhan 5, Hande Sipahi 5 , ¸SuleAyla 6, Benay Daylan 6, Betül Demirci 7 and Fatih Demirci 7,8,* 1 Department of Pharmacology, Faculty of Pharmacy, University of Health Sciences, 34668 Istanbul, Turkey 2 Department of Pharmacognosy, School of Pharmacy, Istanbul Medipol University, 34810 Istanbul, Turkey;
[email protected] 3 Department of Pharmacognosy, Graduate School of Health Sciences, Anadolu University, 26470 Eski¸sehir, Turkey 4 Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Health Sciences, 34668 Istanbul, Turkey;
[email protected] 5 Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Yeditepe University, 34775 Istanbul, Turkey;
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[email protected] (H.S.) 6 Department of Histology and Embryology, School of Medicine, Istanbul Medipol University, 34810 Istanbul, Turkey;
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[email protected] (B.D.) 7 Faculty of Pharmacy, Anadolu University, 26470 Eski¸sehir, Turkey;
[email protected] 8 Department of Pharmacognosy, Faculty of Pharmacy, Eastern Mediterranean University, Famagusta, 99628 Famagusta, Cyprus * Correspondence:
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[email protected] (F.D.); Tel.: +90-2164189616 (M.E.O.); +90-2223350580 (F.D.) Academic Editors: Marcello Locatelli, Simone Carradori and Andrei Mocan Received: 17 March 2020; Accepted: 7 May 2020; Published: 10 June 2020 Abstract: The air-dried aerial parts of Phlomis russeliana (Sims) Lag. Ex Benth. was extracted by methanol and fractionated by n-hexane, dichloromethane, and ethyl acetate, respectively.