Integrin Beta 7 Polyclonal Antibody Purified Rabbit Polyclonal Antibody (Pab) Catalog # AP54281

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Integrin Beta 7 Polyclonal Antibody Purified Rabbit Polyclonal Antibody (Pab) Catalog # AP54281

10320 Camino Santa Fe, Suite G San Diego, CA 92121 Tel: 858.875.1900 Fax: 858.622.0609 Integrin beta 7 Polyclonal Antibody Purified Rabbit Polyclonal Antibody (Pab) Catalog # AP54281 Specification Integrin beta 7 Polyclonal Antibody - Product Information Application IHC-P Primary Accession P26011 Reactivity Rat Host Rabbit Clonality Polyclonal Calculated MW 87411 Integrin beta 7 Polyclonal Antibody - Additional Information Gene ID 16421 Tissue/cell: human glioma tissue; 4% Paraformaldehyde-fixed and Other Names paraffin-embedded; Integrin beta-7, Integrin beta-P, M290 IEL Antigen retrieval: citrate buffer ( 0.01M, pH antigen, Itgb7 6.0 ), Boiling bathing for 15min; Block Format endogenous peroxidase by 3% Hydrogen 0.01M TBS(pH7.4) with 1% BSA, 0.09% peroxide for 30min; Blocking buffer (normal (W/V) sodium azide and 50% Glyce goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Integrin beta 7 Polyclonal Storage Antibody, Unconjugated(bs-1051R) 1:200, Store at -20 ℃ for one year. Avoid repeated overnight at 4°C, followed by conjugation to freeze/thaw cycles. When reconstituted in the secondary antibody(SP-0023) and sterile pH 7.4 0.01M PBS or diluent of DAB(C-0010) staining antibody the antibody is stable for at least two weeks at 2-4 ℃. Integrin beta 7 Polyclonal Antibody - Protein Information Name Itgb7 Function Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is involved in adhesive interactions of leukocytes. It is a receptor for fibronectin and recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Integrin alpha- 4/beta-7 is also a receptor for MADCAM1 and VCAM1. It recognizes the sequence L-D-T in MADCAM1. Integrin alpha-E/beta-7 is a Page 1/2 10320 Camino Santa Fe, Suite G San Diego, CA 92121 Tel: 858.875.1900 Fax: 858.622.0609 receptor for E- cadherin. Cellular Location Membrane; Single-pass type I membrane protein. Integrin beta 7 Polyclonal Antibody - Protocols Provided below are standard protocols that you may find useful for product applications. • Western Blot • Blocking Peptides • Dot Blot • Immunohistochemistry • Immunofluorescence • Immunoprecipitation • Flow Cytomety • Cell Culture Page 2/2 Powered by TCPDF (www.tcpdf.org).

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Supplementary Table 1: Adhesion Genes Data Set
Supplementary Table 1: Adhesion genes data set PROBE Entrez Gene ID Celera Gene ID Gene_Symbol Gene_Name 160832 1 hCG201364.3 A1BG alpha-1-B glycoprotein 223658 1 hCG201364.3 A1BG alpha-1-B glycoprotein 212988 102 hCG40040.3 ADAM10 ADAM metallopeptidase domain 10 133411 4185 hCG28232.2 ADAM11 ADAM metallopeptidase domain 11 110695 8038 hCG40937.4 ADAM12 ADAM metallopeptidase domain 12 (meltrin alpha) 195222 8038 hCG40937.4 ADAM12 ADAM metallopeptidase domain 12 (meltrin alpha) 165344 8751 hCG20021.3 ADAM15 ADAM metallopeptidase domain 15 (metargidin) 189065 6868 null ADAM17 ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme) 108119 8728 hCG15398.4 ADAM19 ADAM metallopeptidase domain 19 (meltrin beta) 117763 8748 hCG20675.3 ADAM20 ADAM metallopeptidase domain 20 126448 8747 hCG1785634.2 ADAM21 ADAM metallopeptidase domain 21 208981 8747 hCG1785634.2|hCG2042897 ADAM21 ADAM metallopeptidase domain 21 180903 53616 hCG17212.4 ADAM22 ADAM metallopeptidase domain 22 177272 8745 hCG1811623.1 ADAM23 ADAM metallopeptidase domain 23 102384 10863 hCG1818505.1 ADAM28 ADAM metallopeptidase domain 28 119968 11086 hCG1786734.2 ADAM29 ADAM metallopeptidase domain 29 205542 11085 hCG1997196.1 ADAM30 ADAM metallopeptidase domain 30 148417 80332 hCG39255.4 ADAM33 ADAM metallopeptidase domain 33 140492 8756 hCG1789002.2 ADAM7 ADAM metallopeptidase domain 7 122603 101 hCG1816947.1 ADAM8 ADAM metallopeptidase domain 8 183965 8754 hCG1996391 ADAM9 ADAM metallopeptidase domain 9 (meltrin gamma) 129974 27299 hCG15447.3 ADAMDEC1 ADAM-like,
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Cd49d Antibody [R1-2] Cat
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Supp Table 6.Pdf
Supplementary Table 6. Processes associated to the 2037 SCL candidate target genes ID Symbol Entrez Gene Name Process NM_178114 AMIGO2 adhesion molecule with Ig-like domain 2 adhesion NM_033474 ARVCF armadillo repeat gene deletes in velocardiofacial syndrome adhesion NM_027060 BTBD9 BTB (POZ) domain containing 9 adhesion NM_001039149 CD226 CD226 molecule adhesion NM_010581 CD47 CD47 molecule adhesion NM_023370 CDH23 cadherin-like 23 adhesion NM_207298 CERCAM cerebral endothelial cell adhesion molecule adhesion NM_021719 CLDN15 claudin 15 adhesion NM_009902 CLDN3 claudin 3 adhesion NM_008779 CNTN3 contactin 3 (plasmacytoma associated) adhesion NM_015734 COL5A1 collagen, type V, alpha 1 adhesion NM_007803 CTTN cortactin adhesion NM_009142 CX3CL1 chemokine (C-X3-C motif) ligand 1 adhesion NM_031174 DSCAM Down syndrome cell adhesion molecule adhesion NM_145158 EMILIN2 elastin microfibril interfacer 2 adhesion NM_001081286 FAT1 FAT tumor suppressor homolog 1 (Drosophila) adhesion NM_001080814 FAT3 FAT tumor suppressor homolog 3 (Drosophila) adhesion NM_153795 FERMT3 fermitin family homolog 3 (Drosophila) adhesion NM_010494 ICAM2 intercellular adhesion molecule 2 adhesion NM_023892 ICAM4 (includes EG:3386) intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)adhesion NM_001001979 MEGF10 multiple EGF-like-domains 10 adhesion NM_172522 MEGF11 multiple EGF-like-domains 11 adhesion NM_010739 MUC13 mucin 13, cell surface associated adhesion NM_013610 NINJ1 ninjurin 1 adhesion NM_016718 NINJ2 ninjurin 2 adhesion NM_172932 NLGN3 neuroligin
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STRUCTURAL INVESTIGATION OF THE COMPLEX OF FILAMIN A REPEAT 21 WITH INTEGRIN αIIb & β3 CYTOPLASMIC TAILS —A POTENTIAL “TRANSMISSION” TO REGULATE CELL MIGRATION JIANMIN LIU Bachelor of Science in Chemical Engineering Changchu University of Technology July, 1999 Master of Science in Chemistry Changchu University of Technology July, 2002 submitted in partial fulfillment of requirements for the degree DOCTOR OF PHILOSOPHY IN CLINICAL-BIOANALYTICAL CHEMISTRY at the CLEVELAND STATE UNIVERSITY August, 2009 This dissertation has been approved for the Department of CHEMISTRY and the College of Graduate Studies by Dissertation Chairman, Edward Plow Ph.D. Department & Date Jun Qin Ph.D. Department & Date Yan Xu Ph.D. Department & Date John Masnovi Ph.D. Department & Date Aimin Zhou Ph.D. Department & Date STRUCTURAL INVESTIGATION OF THE COMPLEX OF FILAMIN A REPEAT 21 WITH INTEGRIN αIIb & β3 CYTOPLASMIC TAILS —A POTENTIAL “TRANSMISSION” TO REGULATE CELL MIGRATION JIANMIN LIU ABSTRACT Cell functions in multi-cellular organisms are strongly depend on the dynamic cooperation between cell adhesion and cytoskeleton reorganization. Integrins, the major cell adhesion receptors, bind to extracellular matrix (ECM) and soluble ligands on the cell surface and link to the actin cytoskeleton inside the cell membrane. In this manner, integrins integrate cell adhesion and cytoskeleton reorganization by acting as a mechanical force transducer and a biochemical signaling hub (Zamir and Geiger 2001). Consequently, integrins are vital for development, immune responses, leukocyte traffic and hemostasis, and a variety of other cellular and physiological processes. Integrins are also are the focal point of many human diseases, including genetic, autoimmune, cardiovascular and others. In terms of the cell-ECM adhesion, integrins can exist in two major states, active, where it binds to appropriate extracellular ligands, and inactive, where it disassociates from extracellular ligands.
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The Concise Guide to Pharmacology 2019/20: Catalytic Receptors
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