A Science and Innovation Audit Report for the Midlands Engine
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Directory of Companies A
65 Directory of Companies A An alphabetical list of pharmaceutical companies, as well as manufacturers and suppliers of products and services for Medicinal Chemistry in Europe 3B PHARMACEUTICALS GMBH Magnusstraße 11 12489 BERLIN DE 3M BELGIUM Canadastraat 11, Haven 1005 2070 ZWIJNDRECHT BE 3V-LSI Rubicondreef 18 3561 JC UTRECHT NL of Companies 4SC AG Am Klopferspitz 19a 82152 MARTINSRIED DE A & D INSTRUMENTS LTD Abingdon Science Park OX14 3YX ABINGDON GB ABBVIE DEUTSCHLAND GMBH & CO. KG Knollstrasse 67061 LUDWIGSHAFEN DE Directory ABCR GMBH Im Schlehert 10 76187 Karlsruhe, GERMANY Contact person: Dr. Ute Kiso Tel: +49 721 95061-0 - [email protected] www.abcr.de Gute Chemie. Welcome to abcr. With abcr, you have access to over 260,000 products from the organic, organometallic and inorganic specialty chemicals area. These can be conveniently ordered via our webshop www.abcr.de > Catalogue & Bulk business from grams to tons > Scale up & Commercial manufacturing from our own facility > Sourcing & Logistic management worldwide > Feasibility studies & Synthesis at the laboratory scale > Custom syntheses & Contract Manufacturing ABSORPTION SYSTEMS 440 Creamery Way Suite 300 PA 19341 EXTON US AC IMMUNE SA EPFL Innovation Park Building B 1015 LAUSANNE FR ACCELA CHEMBIO 9823 Pacific Heights Blvd # F 92121 SAN DIEGO US ACRAF S.P.A. Piazzale della Stazione 40 S. PALOMBA - POMEZIA IT ACROS ORGANICS Janssen Pharmaceuticalaan 3a 2440 GEEL BE ACS Journal of Medicinal Chemistry & ACS Medicinal Chemistry Letters Contact person: Janice E. Silverman, Acquisitions Editor Tel: +1 202-577-5975 [email protected] Journal of Medicinal Chemistry – pubs.acs.org/jmc ACS Medicinal Chemistry Letters – pubs.acs.org/acsmedchemlett In 2017 Journal of Medicinal Chemistry is celebrating 60 years of publishing the field’s best peer-reviewed research. -
Contents Page
Statement of Development Principles: Regeneration Of Boots Campus, Beeston, Nottingham June 2007 STATEMENT OF DEVELOPMENT PRINCIPLES: REGENERATION OF BOOTS CAMPUS, BEESTON, NOTTINGHAM (June 2007) Contents 1. Introduction................................................................................................2 PURPOSE.............................................................................................................................. 2 POLICY CONTEXT................................................................................................................ 3 2. Development Principles ............................................................................4 THE VISION........................................................................................................................... 4 KEY DEVELOPMENT PRINCIPLES ..................................................................................... 4 3. Key Issues ..................................................................................................7 HIGHWAYS AND ACCESS ................................................................................................... 7 BALANCE OF USES ............................................................................................................. 7 LISTED BUILDINGS .............................................................................................................. 9 ENVIRONMENT.....................................................................................................................9 -
Acacia Pharma Group
This document comprises a prospectus (the “Prospectus”) relating to Acacia Pharma Group plc (the “Company” or “Acacia Pharma”) prepared in accordance with the prospectus regulation rules (the “Prospectus Regulation Rules”) of the UK Financial Conduct Authority (the “FCA”) made pursuant to section 73A of the Financial Services and Markets Act 2000, as amended (“FSMA”). This Prospectus has been approved by the FCA as the competent authority under Regulation (EU) 2017/1129 (the “Prospectus Regulation”) and has been filed with and made available to the public in accordance with Rule 3.2 of the Prospectus Regulation Rules. The FCA only approves this Prospectus as meeting the standards of completeness, comprehensibility and consistency imposed by the Prospectus Regulation. Such approval should not be considered as an endorsement of the Company or of the quality of the Ordinary Shares that are the subject of this Prospectus. Investors should make their own assessment as to the suitability of investing in the Ordinary Shares. In addition, this Prospectus has been drawn up as a simplified prospectus in accordance with Article 14 of the Prospectus Regulation. The Belgian Financial Services and Markets Authority (“Belgian FSMA”) was notified of the passporting of this Prospectus in accordance with Article 25 of the Prospectus Regulation. The Company and the Directors, whose names appear on page 39 of this document, accept responsibility for the information contained in this document. To the best of the knowledge of the Company and the Directors, the information contained in this document is in accordance with the facts and this document makes no omission likely to affect its import. -
A Science & Innovation Audit for the West Midlands
A Science & Innovation Audit for the West Midlands June 2017 A Science & Innovation Audit for the West Midlands Contents Foreword 1. Introduction .......................................................................................................................... 1 2. Economic and research landscape .................................................................................... 4 3. The West Midlands SIA Framework ................................................................................. 15 4. Innovation Ecosystem ....................................................................................................... 18 5. Enabling Competencies .................................................................................................... 38 6. Market Strengths ................................................................................................................ 49 7. Key findings and moving forward .................................................................................... 73 Annex A: Case Studies ........................................................................................................ A-1 www.sqw.co.uk A Science & Innovation Audit for the West Midlands Foreword In a year of change and challenge on other fronts, this last year has also been one of quiet revolution. This year has seen a dramatic increase across the UK in the profile of science and innovation as a key driver of productivity and its potential to improve the way our public services are delivered. The potential has always -
Playing to One's Strengths
ISSUE 29 Quarterly Journal - December 2018 NEWS COMMENT and ANALYSIS on SPINOUTS from UK HEIs Playing to one’s strengths As we have frequently remarked, and as the figures given in our Quarterly Journals demonstrate, spinout activity—new spinouts created, investment, exits - is highly concentrated in the South East of England. While universities such as Oxford and Cambridge, Imperial and UCL, go from strength to strength, making the most of their favourable environment - business, technology, investment - outside the ‘golden triangle’ it is not possible for universities to replicate the same conditions, and they must identify their own strengths and put them to maximum effect. We have two examples in this issue: Univeresity of Birmingham Enterprise’s account of the commercialisation collaboration between eight Midlands universities (p17), and our Spotlight feature on Swansea University (p15), which has evolved a technology transfer model tailored specifically to its own circumstances. Encouragingly, the Knowledge Exchange Framework (KEF) currently under development acknowledges this issue, and has set out to group universities in clusters, so that universities in the most favoured environments can be assessed against their peers, and others judged by criteria more relevant to their own environments; see our report on p13. Since the publication of our previous Quarterly Journal, the sale of Spinouts UK to Beauhurst has been completed. Henry Whorwood of Beauhurst explains what this means in terms of tracking and profiling spinout companies on p8. There will be a transitional handover period, with Spinouts UK founder and editor Jonathan Harris continuing to produce the Quarterly Journals, while Beauhurst gradually takes over the data collection activities. -
A Preclinical Evaluation of the Discriminative And
NP5101_proof ■ 12 June 2013 ■ 1/11 Neuropharmacology xxx (2013) 1e11 Contents lists available at SciVerse ScienceDirect Neuropharmacology journal homepage: www.elsevier.com/locate/neuropharm 1 56 2 A preclinical evaluation of the discriminative and reinforcing 57 3 58 4 properties of lisdexamfetamine in comparison to D-amfetamine, 59 5 fi 60 6 methylphenidate and moda nil 61 7 62 a,* a a a b 8 Q5 David J. Heal , Niki W. Buckley , Jane Gosden , Nigel Slater , Charles P. France , 63 9 David Hackett c 64 10 65 a 11 RenaSci Ltd, BioCity Nottingham, Pennyfoot Street, Nottingham NG1 1GF, UK 66 b University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA 12 c Shire Pharmaceutical Development Ltd, Hampshire International Business Park, Chineham, Basingstoke RG24 8EP, Hampshire, UK 67 13 68 14 69 15 article info abstract 70 16 71 17 Article history: Lisdexamfetamine dimesylate, which consists of L-lysine covalently bound to D-amfetamine, is the first 72 18 Received 12 December 2012 prodrug for treating ADHD. Its metabolic conversion to yield D-amfetamine by rate-limited, enzymatic 73 19 Received in revised form hydrolysis is unusual because it is performed by peptidases associated with red blood cells. Other 74 3 April 2013 20 stimulants shown to be effective in managing ADHD include D-amfetamine, methylphenidate and 75 Accepted 13 May 2013 21 modafinil. All have the potential for misuse or recreational abuse. The discriminative and reinforcing 76 effects of these compounds were determined in rats using a 2-choice, D-amfetamine (0.5 mg/kg, i.p.)- 77 22 Keywords: cued drug-discrimination test, and by substitution for intravenous cocaine in self-administration. -
UKRI Open Access Policy: Summary of Stakeholder Workshops and Consultation Meetings
UKRI Open Access Policy: Summary of stakeholder workshops and consultation meetings Contents: 1. UK Research and Innovation Open Access Review Universities Stakeholder Roundtable – Meeting Note..................................................................................................................................2 2. UKRI Open Access Review Stakeholder Roundtable Libraries, Research Management and Knowledge Exchange – Meeting Note..........................................................................................12 3. UK Research and Innovation Open Access Review Stakeholder Academies and Learned Societies Roundtable – Meeting Note...........................................................................................21 4. UKRI Open Access Review Stakeholder Roundtable Publishers Association – Meeting Note....32 5. UKRI Open Access Review International Association of Scientific, Technical and Medical Publishers Stakeholder Roundtable – Meeting Note....................................................................41 6. UKRI Open Access Review Stakeholder Roundtable Open Access Scholarly Publishers Association (OASPA) – Meeting Note...........................................................................................50 7. UKRI Open Access Review Licensing and Copyright Retention Workshop – Meeting Note........59 8. UKRI Open Access Review Metadata Workshop - Meeting Note................................................78 9. UKRI Open Access Review Researcher Workshop – Meeting Note...........................................93 -
Intrinsic Features in Spinouts UK
ISSUE 27 Quarterly Journal - June 2018 NEWS COMMENT and ANALYSIS on SPINOUTS from UK HEIs Measuring what is important TEF, REF, then KEF – university staff are used to dealing with Government TLAs and the administration that they entail, and the KEF (Knowledge Exchange Frame- work) brings this activity into the space covered by Spinouts UK. We are well aware that our focus on spinouts and start-ups is only one part of the picture; indeed, as stressed by the report by the MacMillan group in September 2016 on ‘University Knowledge Exchange (KE) Framework: good practice in technology transfer’, “the processes of exploiting university intellectual property through spinning out companies or licensing . is only one route to impact from the many being examined in the knowledge exchange (KE) framework.” The development of the KEF was discussed in detail at the PraxisAuril conference in May, and some of the concerns and questions of the technology transfer and commercialisation professionals in the audience given a full airing. The KEF is due to be rolled out from late autumn onwards, but this timescale means that the first KEF will be restricted to existing data, with other data capture part of an ongoing process. As Tamsin Mann, Head of Policy at PraxisAuril, noted in a blog about the conference discussion, “Evidence underpinning the KEF needs to be challenging and not just measure ‘the good stuff’. There is a clear desire, from PraxisAuril members at least, to capture the quality of engagement and not just the quantities.” Clarity is required, as the KEF is developed, on who it is for and the kind of feedback needed as outputs, and what the KEF can help institutions to do that is not possible with current arrangements. -
Medilink East Midlands Innovation Day Thursday 15 June 2017 Delegate List
Medilink East Midlands Innovation Day Thursday 15 June 2017 Delegate List Firstname Surname Job Title Company Aisha Ajij Project Support and Industry Liaison Officer East Midlands Academic Health Science Network Jim Allen Development Director Datalink Electronics Ltd Lindsay Allen Senior Programme Manager D2N2 Local Enterprise Partnership (LEP) Clare Allen Speech Language Therapist The Ear Foundation Michele Archer Business Development Haughton Design Alex Archibald Business Development Manager Midlands Health Innovation Carol Aries Non Executive Director Medilink East Midlands Richard Arm Research Fellow Nottingham Trent University Chris Armstrong Marketing Manager Health Enterprise East Ltd Judith Asiimwe Team Leader Ayva Pharma Ltd Shaun Atherton Innovation Engineer Nottingham Trent University Sheetal Athlaye Audiologist The Ear Foundation Edward Attenborough CEO Attenborough Dental Laboratories Ltd Jensen Aw CTO Attenborough Dental Laboratories Ltd Khushy Bahra Account Manager Ayva Pharma Ltd John Bannard Managing Director Siltech Ltd Tim Bassford Creative Director Spinning Clock Ltd Nick Bennett Head of Product Development IVC Brunel Healthcare James Bennett Junior Designer Pd-m International Kate Beresford Director Kate Beresford Associates George Billingham Account Manager Ayva Pharma Ltd Mark Bird Head of IT Upperton Ltd Nicholas Blackwell Director OCB Media Chris Blatchford Senior Analytical Specialist 3M UK Ltd Sarah Bolton Business Manager CHEATA Clare Booth Partnership Development Manager Department for International Trade -
Building Our Industrial Strategy: Green Paper
Green Paper January 2017 Contents Foreword .................................................................................................................................... 3 Introduction ............................................................................................................................... 5 How to respond to this Green Paper ................................................................................ 8 Summary ..................................................................................................................................10 Investing in science, research and innovation ............................................................25 Developing skills ...................................................................................................................37 Upgrading infrastructure ....................................................................................................51 Supporting businesses to start and grow ....................................................................61 Improving procurement ......................................................................................................71 Encouraging trade and inward investment ..................................................................79 Delivering affordable energy and clean growth ..........................................................89 Cultivating world-leading sectors ...................................................................................97 Driving growth across the whole country -
BIO-SCIENCE FACILITY, LOWER PARLIAMENT STREET, NOTTINGHAM Nottingham City Council Lease the OPPORTUNITY
Significant Capital Allowance Investment Opportunity BIO-SCIENCE FACILITY, LOWER PARLIAMENT STREET, NOTTINGHAM Nottingham City Council Lease THE OPPORTUNITY Unique opportunity to acquire a new bio-science incubator facility let on a long lease to a major city council with significant capital allowances providing an attractive post tax return. Prominently located at Lower Parliament Street, Nottingham There are estimated £9,750,000 of available capital allowances to a adjacent to the existing Bio-City buildings within Nottingham’s purchaser which at a higher tax rate of 45% are worth £4,387,500 creative quarter. over a 5 year period. 150 years long-leasehold interest at a peppercorn rent from Nottingham City Council is to provide a loan to the purchaser of Nottingham City Council. £11,011,200 for a 5 years period at a fixed interest rate of 4.50% which equates to £495,484 interest per annum. No amortisation required during this period. Construction commenced in August 2015 on the new Biocity Science building over ground and 4 upper floors providing state of the art laboratory and office accommodation and extending to 52,475 sq ft Purchaser equity requirement of £6,748,800 which after interest NIA. Willmott Dixon is the appointed contractor. charges provides a net annual pre tax yield of 3.18%. To be let to Nottingham City Council for 30 years from completion of this transaction on a full repairing and insuring lease at an initial rent of Post tax annual yields are Year 1 - 7.54%, Year 2 - 6.86%, Year 3 - £714,000 per annum equating to £13.61 per sq ft. -
The British Innovation Fund Investing in the Best of UK University Venturing
The British Innovation Fund Investing in the Best of UK University Venturing For discussion purposes with Professional Investors only 2Q 2020 BRITISH INNOVATION FUND EXECUTIVE SUMMARY Key Areas of Specialty: Agricultural Bio- Technologies technology The BIF has been backed by some of The BIF is managed in the leading local The British Innovation partnership with government pension Deep Tech Life Sciences Milltrust International LLP Fund (BIF) is an schemes in the and Milltrust Agricultural AIFMD-compliant United Kingdom patient capital venture Investments, and supported by an capital fund investing in cutting edge spin- Alternative Advisory team of Nano Tech investment specialists outs emanating from Protein and agricultural and leading UK university research. scientific experts. 2 INVESTMENT PREMISE “Exploration is the engine that drives innovation. Innovation drives economic growth.” - Edith Widder 3 INVESTMENT PREMISE A BRIEF HISTORY OF BRITISH INNOVATION Sir Isaac Newton, PRS 25 December 1642 – 20 March 1726 Sir Alexander Fleming, FRS FRSE FRCS English mathematician, physicist, astronomer, 6 August 1881 – 11 March 1955 theologian, and author widely recognised as one of the Scottish biologist, physician, micro-biologist, most influential scientists of all time and as a key figure and pharmacologist. Inventor of Penicillin. in the scientific revolution. Edward Jenner, FRS FRCPE FLS John Logie Baird, FRSE 17 May 1749 – 26 January 1823 13 August 1888 – 14 June 1946 English physician who was a contributor to the Scottish engineer and innovator. One of the inventors of development of the smallpox vaccine. the mechanical television. Michael Faraday, FRS 22 September 1791 – 25 August 1867 John Adrian Shepherd-Barron, OBE English scientist who contributed to the study 23 June 1925 – 15 May 2010 of electromagnetism and electrochemistry.