The Midlands Engine Science and Innovation Audit Volume 2: Supporting Annexes 30 September 2016

Science and Innovation Audit Volume 2: Supporting Annexes Contents

Annex A: Organisations responding to the e-consultation ...... 1 Annex B: Midlands Engine Innovation Group Vision ...... 2 Annex C: Theme-level data ...... 3 Annex D: Thematic workshop notes ...... 13 Annex E: Further Sci-Val data ...... 32 Annex F: Long list of assets ...... 46 Annex G: Case examples ...... 68 Annex H: Detailed market priority templates ...... 78 Annex I: E-consultation responses ...... 98 Annex J: Driving competitiveness through our Enabling Competencies ...... 109 Annex K: Innovation networks and behaviours ...... 112

Science and Innovation Audit Volume 2: Supporting Annexes

Annex A: Organisations responding to the e- consultation

A.1 The table below lists the organisations who responded to the e-consultation exercise. In some cases, different people from within the same organisation responded, e.g. academics working in different departments of the same university. In addition, two anonymous responses were received.

Organisations responding to the e-consultation

 3M  Leicester City Council

 Aircraft Research Association  Leicester Precision Medicine Institute

 Aston University  Loughborough University

 Aylesbury Vale District Council  Marches Energy Agency

 BBR Optometry  Midlands Aerospace Alliance

 BioCity Group  Mondelez International

 BioStatus  National Grid

 Birmingham City University  Nottingham Trent University

 Campden BRI  Optimec

 City of Wolverhampton Council  QinetiQ

 Collinson Associates  RJ & A E Godfrey

 Coventry University  Rolls-Royce Plc

 Cranfield University  Siemens Wind Power

 De Montfort University  SNC-Lavalin

 Derby Teaching Hospitals NHS Foundation Trust  Staffordshire University

 East Midlands Academic Health Science Network  The Open University

 Encraft  Transport for West Midlands

 Energy Technologies Institute  UK Space Agency

 Faering  UNIP Management

 Freelance Researcher  University Hospitals Birmingham NHSFT

 Greater Birmingham and Solihull LEP  University Hospitals of Leicester

 Greater Lincolnshire LEP  University of Birmingham

 Harper Adams University  University of Derby

 Hexcel Reinforcements UK  University of Leicester

 Invest in Nottingham  University of Nottingham

 Jaguar Land Rover  University of Wolverhampton

 Keele University  Worcestershire Innovation Network

 Leicester and Leicestershire Enterprise Partnership

1 Science and Innovation Audit Volume 2: Supporting Annexes Annex B: Midlands Engine Innovation Group Vision

B.1 Our vision for Midlands Engine Innovation is to convert the great research from the Midlands Universities and the wider research community into commercially successful products and processes for the economic benefit of the UK. By harnessing our scientific research and innovation strengths we will address market failures and market needs, creating a self- sustaining, long-term approach to delivering productivity growth for the region. We will create a system that bridges the ‘readiness’ gap that traditionally exists between concept- proven research and commercial financial investment. We will generate the conditions necessary to build confidence for that investment, accelerating the adoption of technology by industry, and thereby begin a cycle of continual growth for the Midlands Engine region.

B.2 We believe we are well placed to deliver this vision based on the strong academic research and translational research capability in the Midlands Region, drawing on the strengths of the High Value Manufacturing Catapult and the independent research and technology organisations based in the Midlands Engine region.

Midlands Engine Innovation Group Vision

Source: Midlands Engine Innovation Group

2 Science and Innovation Audit Volume 2: Supporting Annexes Annex C: Theme-level data

C.1 The pages below set out the data collected for the SIA for each of the six Themes from the Business Register and Employment Survey (including Location Quotients), and ONS Business Counts. The data are cut by relevant SIC code, and LEP area.

Healthcare, Life Sciences and Translational Medicine

Employment in the Midlands Engine (2009)

Source: BRES

Employment in the Midlands Engine (2014)

Source: BRES

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LQ Midlands Engine vs GB (2014)

Source: BRES

Business Counts (2015)

Source: ONS Business Counts

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Creative, Digital and Design Sector

Employment in the Midlands Engine (2009)

Source: BRES

Employment in the Midlands Engine (2014)

Source: BRES

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LQ Midlands Engine vs GB (2014)

Source: BRES

Business Counts (2015)

Source: ONS Business Counts

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Energy and Low Carbon Technologies

Employment in the Midlands Engine (2009)

Source: BRES

Employment in the Midlands Engine (2014)

Source: BRES

LQ Midlands Engine vs GB (2014)

Source: BRES

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Business Counts (2015)

Source: ONS Business Counts

Transport Technologies

Employment in the Midlands Engine (2009)

Source: BRES

Employment in the Midlands Engine (2014)

Source: BRES

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LQ Midlands Engine vs GB (2014)

Source: BRES

Business Counts (2015)

Source: ONS Business Counts

Advanced Manufacturing and Engineering

Employment in the Midlands Engine (2009)

Source: BRES

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Employment in the Midlands Engine (2014)

Source: BRES

LQ Midlands Engine vs GB (2014)

Source: BRES

Business Counts (2015)

Source: ONS Business Counts

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Agri-food and drink manufacturing and production

Employment in the Midlands Engine (2009)

Source: BRES

Employment in the Midlands Engine (2014)

Source: BRES

LQ Midlands Engine vs GB (2014)

Source: BRES

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Business Counts (2015)

Source: ONS Business Counts

12 Science and Innovation Audit Volume 2: Supporting Annexes Annex D: Thematic workshop notes

Advanced Manufacturing and Engineering

Context

D.1 To inform the development of the Midlands Engine (ME) Science and Innovation Audit (SIA), a stakeholder workshop was held on the 30th June 2016 at the University of Leicester. The workshop focused on the Advanced Manufacturing Theme of the ME SIA. The purpose of the workshop was to engage a broad base of partners in the SIA process and capture their perspectives on the priority strengths, opportunities and gaps in the ME science and innovation offer, focusing specifically within the advanced manufacturing thematic area. This short note provides a summary of the key discussion points from the day.

Feedback on Thematic strengths, opportunities and gaps

D.2 As a core part of the workshop, three break-out groups were asked to answer three questions:

 Q1: Within the Theme, what are the Top 3 current science and innovation strengths, in terms of capabilities or sub-sector specialisms, in the Midlands Engine?

 Q2: In light of market and technology changes in the Theme, what are the Top 3 potential science and innovation strengths, in terms of capabilities or sub-sector specialisms, in the Midlands Engine?

 Q3: What do you think are the Top 3 gaps or weaknesses in the ‘innovation ecosystems’ in the Midlands Engine that need to be addressed over the next 5 years?

 Table 1 over the page presents a summary of the key feedback from each of the break- out groups.

D.3 Further to this Theme-specific feedback, it is also important to note that stakeholders at the workshop stressed the importance of ensuring that linkages/synergies between the six Themes of the SIA are identified and recognised fully whilst work progresses to develop the SIA. The need for a consistent focus on identifying those priorities that will drive productivity growth and create high value jobs was also noted.

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Table 1: Summary of feedback from the three break-out groups Q1. Current strengths Q2. Potential strengths Q3. Gaps/weaknesses Blue  Through-life engineering services (TES)  Digital manufacturing: with prototypes and  Skills – problems in retention and Group  Additive manufacturing (e.g. at MTC, WMG) design undertaken via modelling and knowledge around software and analytics. simulation Need more apprenticeships.  Composites and lightweight structures  Transfer of motor sport innovation practices  There is a perception by government and in the region around the Silverstone F1 investors that the Midlands is ‘not the place cluster to broader advanced manufacturing to be’. industries  Attractiveness of the ME for FDI.  Advanced sensing and instrumentation expertise.

Yellow  Materials engineering and technology.  Systems engineering – need for more agility  SME access to facilities and space for Group Ability to provide science, transformation and to be smarter/quicker/more cost equipment and people. There needs to be and industry inputs. effective through virtual development. more shared provision/access to big kit etc.  Facilities and infrastructure / heritage.  Regulatory framework and imperatives (e.g.  Movement of people between academic and Critical mass and Catapults, presence of the C02), provide regional manufacturing industry in both directions. This should be ‘whole innovation chain’. businesses with an opportunity easier in the ME due to proximity but there  Materials formulation design, which is cross  Need to exploit the Midlands network more, are barriers at present. sector (space, health, food, automotive and e.g. make the area the ‘centre of skills for  Access to skills and knowledge for scale up, aerospace). advanced manufacturing’. design for manufacturers. Need for ‘manufacturing ambassadors’.

Red  Complex systems integration – design,  Closed loop manufacturing – potential to  Insufficient technical talent coming through. Group supply and a supportive research base in develop a circular economy focused on the Need for greater university and business the Midlands. ME’s re-manufacturing capabilities knowledge transfer. Issue is how to get less  Automation – precision processes, flexible,  Digital manufacturing - develop engineering sexy skills to be taken up in greater large scale, adaptive, intelligent. UK services through the greater use of industry numbers. strength lies in within translation to industry. simulation/visualisation etc. to create  Leadership for change and innovation  Advanced materials for extreme conditions - comparative advantage for ME management. this is a niche and specific area for use in manufacturing firms.  vertical integration across the materials engineering e.g. lighter, stronger, more business base, and supply chain flexible, more resilient to high/low inefficiencies temperatures etc.

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Implications for the SIA

Looking across the feedback from the break-out groups, three specific areas of regional strength in relation to science and innovation activity within the Theme can be identified:

Advanced materials engineering and application, particularly additive manufacturing, light-weighting (including composites), materials for extreme conditions and materials for formulation design, which is cross sectoral (including space, health, food, automotive and aerospace),

Digital manufacturing, using computer-based systems for product and process design/development covering simulation, visualisation, analytics, demonstration and testing, drawing on both the industrial and research capacity across the region, including the HVM Catapult Centres etc.

Manufacturing systems integration – with the ability to translate science into new product/process development quickly. The Midlands has a strong design, supply and research base in place to aid this process, and a range of research and technology assets; this area also covers a wide range of advanced manufacturing industries. The presence of major global manufacturers in the ME, with significant R&D capabilities and budgets, is a major asset for the UK.

These three suggested focus areas will be considered and tested more fully over the next few weeks as work progresses to develop the ME SIA document.

It is also noted that all three groups identified that there is a lack of skills, particularly in the areas of software and analytics.

SQW,

5 July 2016

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Science and Innovation Audit Volume 2: Supporting Annexes

Agri-food and Drink Manufacturing and Production

Context

To inform the development of the Midlands Engine (ME) Science and Innovation Audit (SIA), a stakeholder workshop was held on the 7 July 2016 at the University of Lincoln. The workshop focused on the Agri-food and drink manufacturing and production Theme of the ME SIA. The purpose of the workshop was to engage a broad base of partners in the SIA process and capture their perspectives on the priority strengths, opportunities and gaps in the ME science and innovation offer, focusing specifically within the agri-food and drink thematic area.

Feedback on Thematic strengths, opportunities and gaps

As a core part of the workshop, three break-out groups were asked to discuss three questions:

 Q1: Within the Theme, what are the Top 3 current science and innovation strengths, in terms of capabilities or sub-sector specialisms, in the Midlands Engine?

 Q2: In light of market and technology changes in the Theme, what are the Top 3 potential science and innovation strengths, in terms of capabilities or sub-sector specialisms, in the Midlands Engine?

 Q3: What do you think are the Top 3 gaps or weaknesses in the ‘innovation ecosystems’ in the Midlands Engine that need to be addressed over the next 5 years?

 Table 1 over the page presents a summary of the key feedback messages from each of the break-out groups.

Further to this Theme-specific feedback, it is also important to note that stakeholders at the workshop stressed the importance of ensuring that linkages between the six Themes of the SIA are identified and recognised in progressing the work. The need for a consistent focus on identifying those priorities that will drive productivity growth and create high value jobs was also noted.

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Science and Innovation Audit Volume 2: Supporting Annexes

Table 1: Summary of feedback from the three break out groups Current strengths Potential strengths Gaps/weaknesses Red  Food manufacturing and engineering  Earth observation – research by ME  Sustainable intensification of agriculture – excellence – evidenced by work throughout universities spanning food, agri-tech and the not enough work is being done in this area the ME universities, the presence of major environment e.g. at Universities of currently and this is a major global global food and drink firms and various Nottingham and Leicester, and links to the challenge. The capabilities currently exist Queen’s Awards for exports etc. Satellite Applications Catapult in Harwell. but are not being employed to respond to  Centres of Excellence – representing a  Nutritional supply chain – understanding the this challenge. Includes urban farming and strong institutional underpinning, including effect of processing on the nutrients in food, making better use of spaces in city for example, the Agricultural Engineering with relevant research in the fields of health environments. It is also important to Precision Innovation Centre, the National and wellbeing/nutraceuticals, genetics and understand and develop greater resilience in Centre for Precision Farming, the National new food. the food chain/system. Centre for Food Manufacturing, Warwick  Data – the production, measuring and  Food systems and the circular economy – Crop Centre, and Campden BRI (which is monitoring of data, including sensors. This minimising waste, including through the located c.10 miles south of Stratford-on- has the potential to help consumers, ensure reuse of waste and by-products. Avon in Gloucestershire, just outside of the traceability and impact productivity.  Networking – ensuring connectivity between ME’s formal boundary). academics, industry, etc.  Food standards and quality control – strengths in research areas including nutrition, safety, authenticity and traceability etc.

Green  Cross-sector innovation in integrated  Raising innovation aspirations and strategic  Potential synergies between health and processing – for example in automation, in capabilities in the sector – risk taking SMEs food/drink sectors are not being fully which the Universities of Nottingham and could do more on this. exploited at present – this is a major Loughborough have major strengths. Also  Intensification of production through opportunity for the ME. includes robot and human interaction and sustainable innovations – increasing yield,  Valuing by-products and driving more positioning. etc. ME has the facilities and research innovation in the circular economy.  Higher level technical skills – particularly in required to underpin this including  Access to finance for SMEs and a research in the food industry, where the ME capabilities in agriculture, technology and disconnect between some of the scientific has strong practical experience, which gives STEM. This needs to be exploited, research undertaken by ME universities and it real comparative advantage. particularly potential cross-sector synergies. the R&D requirements of firms.  The geography and land-use of the region is  Sensor and big data usage – there are an important strength. The physical strong capabilities in sensors and food proximity of farming/agricultural activities diagnostics. Potential to integrate sensors with major production sites in industry and throughout the process – in the field, during research centres of excellence together the manufacturing process, etc. Food provide a compelling case to investors. diagnostics requires formulation and

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Current strengths Potential strengths Gaps/weaknesses There is a large critical mass of companies precision engineering, which are both that encompass the supply chain from start- strengths. Cross-sector opportunities exist, to-finish (growing, processing, consultancy including aerospace/earth observation. services, etc.) in a wide variety of areas, providing cost efficiencies, including reduced ‘food miles’, which is increasingly important to consumers, and aligns with the on-going focus of producers for a dedicated supply chain in which they can gain efficiencies, innovate and maintain tight management control.

Blue  STEM skills and competence in ME – the  Precision in agri-food – potential across the  Skills shortages around driving innovation people and range of academic and research whole chain, employing automation and across industry – the ME has strengths in centres across the ME geography. Opens making use of data. research, but is not doing enough to up possibilities for integrated end-to-end  Packaging innovation – potential benefits for translate this into industry. Additionally, skills solutions and the use of by-products. portion control, package sizing, convenience requirements are changing fast as  Manufacturing and processing – food and use-by date. complexity increases and new disruptive manufacturers have strong representation, technologies emerge e.g. in data,  Consumer experience – developing a automation and engineering. with all elements of the food chain based in greater understanding of health and the area. The region has some strengths in wellbeing/nutraceuticals agenda. There is  Knowledge of regional capabilities and food packaging (which can have benefits for strength in the diversity of the region. expertise, within and across industry and the health and traceability) e.g. in Spalding, research base. Grimsby, but it was recognised that some  Knowledge of what the key growth markets major corporations often look abroad to get are globally – market and technology drivers specialist packaging inputs. of change.  Links to industry across all 27 ME universities – evidenced by the significant value of Innovate UK funding secured for innovation activities in the thematic area.

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Implications for the SIA

As indicated in Table 1, the feedback from the breakout groups was fairly broad, and there was a consensus around any specific fine-grained priorities for the ME SIA. Indeed, the feedback identified consistently that a key strength of the ME is the scale and breadth of activity across both the industry and research base in the Theme - from primary agriculture, through to manufacturing, processing, packaging, and distribution. Many attendees at the workshop referred to an integrated ‘food system’.

However, looking across the feedback from the breakout groups, and drawing on the evidence on science and innovation strengths assembled for the SIA, three key opportunity areas can be identified:

 Food and drink packaging innovation, drawing on the significant manufacturing strengths and legacy in the region, and responding to changes in demand from consumers e.g. on portion control, package sizing, product life-span, counterfeiting/security, RFID sensors and links to the health agenda etc. Intelligent packaging is predicted to be a major growth area over the coming years.

 Food and drink quality improvement, again drawing on the significant manufacturing and processing strengths in the region and its research base, focused on driving innovation in food and drink manufacture, including more nutrition/less sugar, salt and fat etc., food safety and quality (including soil quality and health), and the sustainable use of by-products. The specific link between food/drink and the need to drive improved health outcomes for the population was raised by many workshop attendees.

 Advanced engineering for agriculture, including research, design and manufacture of instruments and appliances to support precision farming (e.g. robotics, satellites, sensors), and the manufacture of agricultural machinery.

Three further headline observations are made by the SQW team:

 The exploitation of data and digital technologies was identified consistently across the workshop as a potential opportunity area, with an imperative to develop the region’s capacity to use data to drive improvements in efficiency and productivity. The ME’s distinctive ‘offer’ in this area was not identified explicitly, as such, this is not considered to be a priority area in its own right for the SIA going forward; rather it should be seen as an important enabler of activity within this theme.

 The coordination of innovation and research across the ME was identified as an issue by the workshop attendees, where action is required going forward. This ‘cross- cutting’ issue will need to be reflected fully in the SIA, across all six of the Themes.

 Skills was identified as an important factor for the Theme, both as a ‘positive’ with a strong existing technical base, and a ‘weakness’ with perceived gaps in terms of new cohorts of people coming into the industry and the ‘delay’ in skills providers to respond to the changing skills needs of firms.

SQW, 12 July 2016

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Digital, Creative and Design Sector

Context

To inform the development of the Midlands Engine (ME) Science and Innovation Audit (SIA), a stakeholder workshop was held on the 24th June 2016 at Aston University, Birmingham. The workshop focused on the Digital, Creative and Design Sector Theme of the SIA. The purpose of the workshop was to engage a broad base of partners in the SIA process and capture their perspectives on the priority strengths, opportunities and gaps in the ME science and innovation offer, focusing specifically within the digital, creative and design thematic area. This short note provides a summary of the key discussion points from the day.

Feedback on Thematic strengths, opportunities and gaps

As a core part of the workshop, three break-out groups were asked to discuss three questions:

 Q1: Within the Theme, what are the Top 3 current science and innovation strengths, in terms of capabilities or sub-sector specialisms, in the Midlands Engine?

 Q2: In light of market and technology changes in the Theme, what are the Top 3 potential science and innovation strengths, in terms of capabilities or sub-sector specialisms, in the Midlands Engine?

 Q3: What do you think are the Top 3 gaps or weaknesses in the ‘innovation ecosystems’ in the Midlands Engine that need to be addressed over the next 5 years?

 Table 1 over the page presents a summary of the key feedback from each of the break- out groups.

Further to this Theme-specific feedback, it is also important to note that stakeholders at the workshop stressed the importance of ensuring that linkages between the six Themes of the SIA are identified and recognised in progressing the work. In this context, the crucial role of digital and design skills as ‘enabling’ disciplines was highlighted. Skills and supporting capabilities around digital design (including large and small scale industrial design) were highlighted as being crucial to the ongoing ability of the ME to compete and innovate across all sectors and technology areas.

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Table 1: Summary of feedback from the break out groups Current strengths Potential strengths Gaps/weaknesses Blue  Design expertise covering  Wearable textiles and smart  Retaining talent, e.g. computer science transport/advanced manufacturing, industrial materials/technologies graduates pulled to FPS sector in London design, products and ergonomics etc.  3D printing and design – glass, ceramics,  Branding issue – negative perception of the  Gaming – simulation, gamification, data etc. ME area as a whole – especially for young capture, motion capture, and the  Digital management of logistics, e- people. Need a coherent, joined up regional programming strengths underpinning these commerce, supply chains, redistributed approach across the ME capabilities manufacturing  Lack of a global digital company in this  Data science and AI, including machine  New media and communications space – no Google, Amazon, Facebook etc. learning. Applied to medical imaging, automotive connectivity, autonomous  Craft maker movements, building on the vehicles, and cyber security. strong heritage of the ME

Yellow  Gaming and simulation, and their application to other industries through VR modelling  Need for long term planning/sustainability in  Sustainable design – environment and energy the development of new innovative products/services – there is no plan in place  Digital skills across the ME for what happens after funding for pilot  Applications of digital tools/technologies/capabilities to other growth sectors of the ME economy projects end. – health, mobility/transport, energy  Need to go beyond R&D and actually implement. More Knowledge Transfer Note: the yellow group chose to combine current and potential strengths in their feedback Partnerships needed, tax credits for implementation?  Need to be more innovative and embrace change more quickly

Red  Games design – Staffordshire University  Wearable technology and creativity -  Gaps in links between different creative and and Leamington Spa, AI skills fashion/design, textiles, Internet of Things design clusters in ME  Cyber security – HE courses and research,  Analysis of big data held by public bodies  Lack of mutual understanding between graduate pathways, building on the cluster and data security engineers and designers at Malvern and the corridor running south to  Craft and creativity – 3D printing, jewellery,  Absence of regional body to drive Cheltenham etc. glass, ceramics, shoes collaboration, improve access to funding  Transport design – Coventry, Silverstone, and link SMEs with academia Milton Keynes

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Implications for the SIA

Looking across the feedback from the breakout groups, three specific areas of regional strength in relation to science and innovation activity within the Theme can be identified:

 Cyber security, focused on clusters of SMEs and large firms across the region (including in Malvern and Nottingham), and research centres (e.g. at Warwick, Birmingham), across the range of defence/public sector and commercial/consumer cyber security (including Qinetiq).

 Smart design for advanced manufacturing, applying the region’s design excellence, including digital design, modelling and simulation excellence, to a wide range of industries including automotive, med-tech, transport, and energy (including sustainable design)

 Game design and development, drawing on both established industrial clusters across the region and science and research excellence in computer science, serious games, simulation, visualisation and artificial intelligence etc.

The potential opportunities from the broader market developments around ‘Big Data’ and the ‘Internet of Things’ (including wearable technology) were also discussed at the session. The ME has genuine research excellence in these areas however, there is a recognition that the region’s comparative advantage and specialisation in these highly competitive areas is not yet established fully; the ME’s competence in ‘Big Data’ and the ‘Internet of Things’ should therefore be considered as part of the Theme’s enabling role across the SIA more broadly.

SQW,

1 July 2016

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Energy and Low Carbon

Context

To inform the development of the Midlands Engine (ME) Science and Innovation Audit (SIA), a stakeholder workshop was held on the 27th June 2016 at Nottingham University. The workshop focused on the Energy and Low Carbon Theme of the ME SIA. The purpose of the workshop was to engage a broad base of partners in the SIA process and capture their perspectives on the priority strengths, opportunities and gaps in the ME science and innovation offer, focusing specifically within the energy and low carbon thematic area.

Feedback on Thematic strengths, opportunities and gaps

As a core part of the workshop, two break-out groups were asked to discuss three questions:

 Q1: Within the Theme, what are the Top 3 current science and innovation strengths, in terms of capabilities or sub-sector specialisms, in the Midlands Engine?

 Q2: In light of market and technology changes in the Theme, what are the Top 3 potential science and innovation strengths, in terms of capabilities or sub-sector specialisms, in the Midlands Engine?

 Q3: What do you think are the Top 3 gaps or weaknesses in the ‘innovation ecosystems’ in the Midlands Engine that need to be addressed over the next 5 years?

 Table 1 over the page presents a summary of the key feedback from each of the break- out groups.

Further to this Theme-specific feedback, it is also important to note that stakeholders at the workshop stressed the importance of ensuring that linkages between the six Themes of the SIA are identified and recognised in progressing the work. The need for a consistent focus on identifying those priorities that will drive productivity growth and create high value jobs was also noted.

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Table 1: Summary of feedback from the two break out groups Current strengths Potential strengths Gaps/weaknesses Blue  DC interconnectors and HV DC – an area  Intelligent mobility - low emissions vehicles  Skills shortages (e.g. power system where the ME has longstanding international (Coventry) and driverless cars (Milton engineers) and poaching by HS2 in leadership. Key players include: National Keynes) Birmingham. Energy Research Accelerator Grid; GE; Alstom; Siemens; Nottingham  Heat networks (Smart Energy Network is beginning to counter this issue. University; and various niche Demonstrator for 12,000 people at Keele)  Activity at Leicester around Big Data, the consultancies/service providers etc. and community energy projects (Corby) Internet of Things and the Space Centre is  Drives, motors and power systems,  Hydrogen, including as a fuel cell for not being picked up elsewhere/by industry including links to transport – academic vehicles. Strengths at Birmingham, strengths and industrial capabilities e.g. Loughborough, and Open University/Shell through GE at rugby partnership  The ME area has a strong innovation culture around energy and low carbon, which attracts big players and SMEs.

Red  Energy and Housing – for both new build  Smart energy networks and systems  Impact of Brexit on funding and international and refurbishments e.g. Milton Keynes integration, including integration of electric research collaborations Smart Cities project and Nottingham energy vehicles  Lack of co-ordination, leadership and pilot project  Modular nuclear power generation governance across the ME geography  Testing, manufacture and application of infrastructure – Birmingham, Nuclear  Lack of demand from public bodies to energy storage technologies covering both Energy CDT implement new technologies, new energy thermal and batteries. Strengths at WMG,  Unconventional energy – monitoring and sources, and shift towards a smart cities Nottingham, Birmingham, and the Smarter regulation of fracking through British approach Network Storage facility in Leighton Buzzard Geological Survey, strengths at Nottingham etc. and Leicester  Bio energy – Research institute at Birmingham, project using waste to generate energy in Nottingham, also waste to energy at Aston, and Johnston Matthey – a leading firm in sustainable technologies

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Implications for the SIA

As indicated in Table 1, the feedback from the breakout groups was fairly broad, and there was a consensus around any specific fine-grained priorities for the ME SIA. However, looking across the feedback from the breakout groups, and drawing on the evidence on science and innovation strengths assembled for the SIA, two key opportunity areas can be identified:

 Energy for ‘smart transport’, covering the range of regional excellence in the business and research bases around low emissions and autonomous vehicles, energy storage (battery technologies), and advanced ‘conventional’ drives, motors and power systems.

 Energy systems integration and networks, drawing on the well-established industrial base across the region in energy generation and distribution, consultancy and technical expertise, research centres, demonstrators, and the Energy Research Accelerator.

 Strengths and opportunities around ‘thermal’ energy (heat and cold) which are evident in the Energy Research Accelerator (recipient of £20m capital investment from Government) and in the Catapult’s ‘Smart Systems and Heat’ Programme, were also identified in the workshop, and should be considered in progressing the SIA.

 The coordination, profile and strategic focus of science and innovation in the ME was also identified as an issue by the workshop where action is required going forward. This ‘cross-cutting’ issue will need to be reflected fully in the SIA, across all Themes.



SQW,

1 July 2016

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Healthcare, Life Sciences and Translational Medicine

Context

To inform the development of the Midlands Engine (ME) Science and Innovation Audit (SIA), a stakeholder workshop was held on the 24th June 2016 at Aston University, Birmingham. The workshop focused on the Healthcare, Life Sciences and Translational Medicine Theme of the ME SIA. The purpose of the workshop was to engage a broad base of partners in the SIA process and capture their perspectives on the priority strengths, opportunities and gaps in the ME science and innovation offer, focusing specifically within the health thematic area. This short note provides a summary of the key discussion points from the day.

Feedback on Thematic strengths, opportunities and gaps

As a core part of the workshop, three break-out groups were asked to discuss three questions:

 Q1: Within the Theme, what are the Top 3 current science and innovation strengths, in terms of capabilities or sub-sector specialisms, in the Midlands Engine?

 Q2: In light of market and technology changes in the Theme, what are the Top 3 potential science and innovation strengths, in terms of capabilities or sub-sector specialisms, in the Midlands Engine?

 Q3: What do you think are the Top 3 gaps or weaknesses in the ‘innovation ecosystems’ in the Midlands Engine that need to be addressed over the next 5 years?

 Table 1 over the page presents a summary of the key feedback from each of the break- out groups.

Further to this Theme-specific feedback, it is also important to note that stakeholders at the workshop stressed the importance of ensuring that linkages between the six Themes of the SIA are identified and recognised in progressing the work. The need for a consistent focus on identifying those priorities that will drive productivity growth and create high value jobs was also noted.

26 Science and Innovation Audit Volume 2: Supporting Annexes

Table 1: Summary of feedback from the three break out groups Q1. Current strengths Q2. Potential strengths Q3. Gaps/weaknesses Blue  Technological developments and  Medical devices development and  Lack of funding from VC community for Group applications of diagnostic imaging e.g. manufacture business start/scale-up in the ME region Nottingham, Lincoln, Warwick  Post graduate training to bridge the skills  Lack of LEP support and a representative  Bioinformatics application e.g. Nottingham gap between academia and industry body/governance model for the Theme at a Trent, Warwick, Birmingham  Drug discovery e.g. Nottingham, Leicester, pan ME level  Large, diverse, and stable population for Milton Keynes  Low profile of ME (relative to some clinical trials competitor areas) in terms of the UK’s life sciences agenda

Yellow  Infrastructure: clinical trials (large, stable,  Defence medicine – treatments, analytical  Lack of ME level management and Group diverse population) and strengths in tools, rehabilitation branding/marketing subjects allied to medicine  Digital mental health – assessment and  Regionally risk averse and lacking ambition.  Manufacture and translation (of medical intervention. Strengths at MindTech in Including a lack of entrepreneurs, business devices) Nottingham, Aston’s EIT, and related builders, funding and ambition  Defence and trauma medicine – mental Horizon 2020 activity at Warwick  Skills gaps around commercialisation and health, digital intervention, rehabilitation  Transfer of automotive manufacturing exploitation of academic discoveries processes/disciplines into healthcare, e.g. six sigma efficiency

Red  Treatments/new drugs can be developed,  Defence medicine, military trauma and  Lack of funding, especially for SMEs Group validated, trialled and manufactured in the rehabilitation  Lack of collaboration across the ME ME – from lab to market, the ME can  Development and manufacture of devices geography in developing the sector provide a fully integrated solution. and diagnostics, and related clinical trials  Lack of clarity and ambition at the ME level  Manufacturing ability, including CRMOs,  Big data and patient records process engineering skills and supply chain  High volume of skilled people in the ME

27 Science and Innovation Audit Volume 2: Supporting Annexes

Implications for the SIA

Looking across the feedback from the breakout groups, three specific areas of regional strength in relation to science and innovation activity within the Theme can be identified:

 Development and manufacture of medical devices including diagnostic devices, including leveraging the wider technical design and manufacturing legacy/heritage of the region in other advanced and high precision manufacturing sectors e.g. automotive and aerospace.

 Defence and trauma medicine, including treatment, analytical tools and the use of data, and rehabilitation, including linking to the wider defence and security related industries across the region

 Bioinformatics and diagnostic imaging (including the use and development of enabling digital technologies more broadly). This also covers wider emerging digital strengths in relation to assisted living (e.g. mental health and other applications development) and secure big data approaches to patient records (building on the ME region’s clear cyber security capabilities, although further work is required to dimension the genuine regional differentiation and specialisation in this area).

These three suggested focus areas will be considered and tested more fully over the next few weeks as work progresses to develop the ME SIA document.

Two further headline observations are made by the SQW team:

 All groups also identified the large, diverse and stable resident population of the ME area as an asset that can be better leveraged, particularly in supporting the offer of the region as an attractive location for clinical trials. This is important for academic, clinical and business activity, but in isolation, its potential for driving productivity growth and providing a genuinely distinctive and differentiated offer for the region is rather limited; as such, this is not considered to be a priority area in its own right for the SIA going forward. Instead, it should be seen as an important enabler and attractor of wider investment.

 The coordination, profile and strategic focus of science and innovation activity in the ME was identified as an issue by the workshop attendees, where action is required going forward. This ‘cross-cutting’ issue will need to be reflected fully in the SIA, across all six of the Themes.

SQW,

1 July 2016

28

Transport Technologies

Context

To inform the development of the Midlands Engine (ME) Science and Innovation Audit (SIA), a stakeholder workshop was held on the 30th June 2016 at the University of Leicester. The workshop focused on the Transport Technologies Theme of the ME SIA. The purpose of the workshop was to engage a broad base of partners in the SIA process and capture their perspectives on the priority strengths, opportunities and gaps in the ME science and innovation offer, focusing specifically within the Transport Technologies thematic area. This short note provides a summary of the key discussion points from the day.

Feedback on Thematic strengths, opportunities and gaps

As a core part of the workshop, three break-out groups were asked to answer three questions:

 Q1: Within the Theme, what are the Top 3 current science and innovation strengths, in terms of capabilities or sub-sector specialisms, in the Midlands Engine?

 Q2: In light of market and technology changes in the Theme, what are the Top 3 potential science and innovation strengths, in terms of capabilities or sub-sector specialisms, in the Midlands Engine?

 Q3: What do you think are the Top 3 gaps or weaknesses in the ‘innovation ecosystems’ in the Midlands Engine that need to be addressed over the next 5 years?

 Table 1 over the page presents a summary of the key feedback from each of the break- out groups.

Further to this Theme-specific feedback, it is also important to note that stakeholders at the workshop stressed the importance of ensuring that linkages between the six Themes of the SIA are identified and recognised fully as work progresses to develop the SIA. The need for a consistent focus on identifying those priorities that will drive productivity growth and create high value jobs was also noted by attendees.

29 Science and Innovation Audit Volume 2: Supporting Annexes

Table 1: Summary of feedback from the three break-out groups Q1. Current strengths Q2. Potential strengths Q3. Gaps/weaknesses Blue  Smart integrated urban transport systems –  Scale of the market, including environment  People skills and capabilities Group automotive vehicles, rail infrastructure, air and electrification; with regulatory issues  Digital data analytics capabilities and transport systems etc. (e.g. on CO2 emissions) and population software. growth leading to increases in demand for  Science and innovation infrastructure –  Lack of connection between the major universities, Advanced Propulsion energy efficient transport systems capabilities/forward thinking of cities (to Centre, Transport Systems Catapult, High  Tech and digital transport – covering generate demand) and the speed of Value Manufacturing Catapult centres connectivity, cyber security and remote transport technology innovation (MTC, WMG) sensing as part of increasingly smart  High performance vehicles R&D and transport systems production, at scale  Smart transport, using smart product systems, digital and design manufacture.

Yellow  Research and design delivery assets  Environmental management – low carbon  STEM skills gaps Group systems – tracks / sites / across TRLs. technologies and the capability to store and  Unified open data portal especially for Critical mass of assets exists across the ME capture bio energy integration - especially around automotive engineering.  Integrated network sensors and the need for  Cross sector research and design  Autonomous vehicles and robotics – e.g. big data analytics across all modes of fertilisation pilot schemes in Milton Keynes and transport (rail/air/road)

Coventry.  Better cross fertilisation and skills, including Cyber and data security – with obvious the opportunity to network between fields cross-overs into ‘connected’ vehicles etc. and merge projects/technologies.

Red  Aeronautical engineering across engines  System engineering, digital design and  Access to digital resources / facilities and Group components and sub-systems modelling design for manufacturing virtual security  Electrification of transport systems/networks validation.  Electronics – skills and capabilities in the e.g. battery powered vehicles  High value volume manufacturing – supply chain  Propulsion systems, including low carbon electrification, materials, cross sector  Revenue to train and connect highly skilled propulsion (e.g. Advanced Propulsion exploitation etc. people to support all of the above. Centre)  Intelligent data exploitation (transport service)

30 Science and Innovation Audit Volume 2: Supporting Annexes

Implications for the SIA

Looking across the feedback from the break-out groups, three specific areas of regional strength in relation to science and innovation activity within the Theme can be identified:

Next generation vehicles including autonomous and electrical vehicles, and the low carbon technology agenda including advanced/energy efficient propulsion systems (including for both automotive and aerospace).

High performance transport engineering, covering the broad industrial areas of automotive, rail and aerospace (including space) transport, and providing a ‘full spectrum offer’ of excellence from R&D through to design, manufacturing, and high-value support services; this includes the world-class innovation in the technology and motorsport cluster presence in the region (e.g. in Milton Keynes, Northampton). Note that this is explicitly a broad area, drawing on both transport specific and wider engineering and manufacturing capabilities, reflecting the increasing convergence of technologies and processes across transport modes.

Smart transport and systems integration, covering the capture, use and exploitation of user data, and technical expertise and consultancy, to create better, more efficiently managed transport systems and networks.

These three suggested focus areas will be considered and tested more fully over the next few weeks as work progresses to develop the ME SIA document.

Three further headline observations are made by the SQW team based on the feedback from attendees at the workshop:

The Midlands area includes a ‘critical mass’ of transport infrastructure, at the heart of the UK’s connectivity, including rail, air, and road. Given its scale and position, there is an opportunity to collect bigger and better data by creating a more integrated and smarter network. Pockets of excellence within cyber and data security were identified in Birmingham, Malvern and Leicester (and close-by in Gloucestershire); a more integrated network can further enhance the optimisation of human and freight movement.

All three groups mentioned that there was a skills gap, in STEM subjects broadly, and specifically in electronic engineering within the supply chain.

The potential inclusion of logistics in the Theme was raised at the workshop. Logistics was not covered in the initial EoI for the Theme (and therefore was not included in the data analysis), but ‘advanced’ logistics could potentially be considered going forward, particularly related to the transport systems and networks priority area.

SQW,

5 July 2016

31 Science and Innovation Audit Volume 2: Supporting Annexes

Annex E: Further Sci-Val data

Outputs in Top 10 citation percentile for the Midlands Engine 25 and UK

Subject areas

Outputs in Top Outputs in Top Field-Weighted Field-Weighted 10 citation 10 citation Citation Impact Citation Impact percentile (%) - percentile (%) - ME 25 - UK Subject areas ME 25 - UK Chemical Engineering 1.74 1.61 32.4 30.6

Chemistry 1.68 1.63 33.3 33.1

Engineering 1.5 1.51 11.9 12.1

Materials Science 1.42 1.52 20.7 21.6

Energy 1.75 1.59 24.1 21.6

Environmental Science 1.81 1.81 22.6 22.8

Mathematics 1.32 1.38 7.3 7.8

Physics and Astronomy 1.72 1.56 26.1 24

Computer Science 1.31 1.44 6.8 7.7

Decision Sciences 1.74 1.66 14 13.1

Agricultural and Biological Sciences 1.57 1.63 22.4 23.5

Health Professions 1.54 1.49 14.1 13.9

Medicine 1.85 1.7 24.6 22.6

Nursing 1.48 1.28 12.4 11.4

Pharmacology, Toxicology and Pharmaceutics 1.76 1.62 25.2 26.1

Industrial Collaborations leading to co-publications

E.1 The Table below presents data from Sci Val (where available) on the number of co- publications from industrial collaborations between Universities in the Midlands Engine and their industrial partners over the 2013-2015 period.

Co-authored Co-authored Co-authored publication with publication with publication - University UK institutions non-UK institutions total University of Birmingham 381 169 550

University of Nottingham 284 138 422

University of Warwick 170 113 283

University of Leicester 218 46 264

32 Science and Innovation Audit Volume 2: Supporting Annexes

Co-authored Co-authored Co-authored publication with publication with publication - University UK institutions non-UK institutions total Cranfield University 73 71 144

Loughborough University 91 51 142

Aston University 56 14 70

Open University Milton Keynes 44 11 55

Nottingham Trent University 11 15 26

Keele University 22 4 26

Coventry University 9 7 16

De Montfort University 11 3 14

University of Derby 4 6 10

University of Lincoln 7 2 9

Staffordshire University 8 - 8

University of Bedfordshire 6 - 6

Harper Adams University College 3 2 5

Birmingham City University 2 3 5

University of Worcester 2 2 4

The University of Buckingham 1 2 3

University of Wolverhampton 2 1 3

University of Northampton 1 - 1

Competencies

Distinctive Competencies

The Table below sets out the number of universities in the Midlands Engine 25 that have ‘distinctive competences’ identified by Sci Val in the relevant research areas. The definition for distinctive competencies as defined by Sci Val is provided below.

ME universities with distinctive Research area Subject area competencies in the subject area Food Science 3

Ecology, Evolution, Behaviour and Systematics 2

Agronomy and Crop Science 2 Agricultural and Plant Science 2 Biological Sciences Animal Science and Zoology 1

Soil Science 1

Horticulture 1

Aquatic Science 1

33 Science and Innovation Audit Volume 2: Supporting Annexes

ME universities with distinctive Research area Subject area competencies in the subject area History 8

General Arts and Humanities 8

Philosophy 4

Literature and Literary Theory 3 Arts and Humanities Visual Arts and Performing Arts 3

Religious Studies 2

Music 1

Arts and Humanities (miscellaneous) 1

Biochemistry 4

Physiology 2 Biochemistry, Molecular Biology 1 Genetics and Molecular Endocrinology 1 Biology Genetics 1

Cancer Research 1

Business and International Management 6

Marketing 5

Strategy and Management 5

Management of Technology and Innovation 3 Business, Management General Business, Management and and Accounting Accounting 3

Organizational Behaviour and Human Resource Management 3

Tourism, Leisure and Hospitality Management 2

Chemical Engineering General Chemical Engineering 1

General Chemistry 4

Analytical Chemistry 2

Chemistry Electrochemistry 1

Organic Chemistry 1

Physical and Theoretical Chemistry 1

General Computer Science 8

Computer Networks and Communications 6 Computer Software 6 Science Human-Computer Interaction 5

Information Systems 3

34 Science and Innovation Audit Volume 2: Supporting Annexes

ME universities with distinctive Research area Subject area competencies in the subject area Computer Science Applications 3

Computer Graphics and Computer-Aided Design 1

Artificial Intelligence 1

Decision Management Science and Operations Sciences Research 3

Dentistry Oral Surgery 1

Space and Planetary Science 3

Geochemistry and Petrology 2

Geotechnical Engineering and Engineering Earth and Geology 2 Planetary Sciences General Earth and Planetary Sciences 2

Geology 1

Geophysics 1

Economics and Econometrics 5 Economics, General Economics, Econometrics and Econometrics Finance 4 and Finance Finance 2

Renewable Energy, Sustainability and the Environment 3 Energy Energy Engineering and Power Technology 1

Electrical and Electronic Engineering 7

Mechanical Engineering 6

Biomedical Engineering 4

Control and Systems Engineering 3

Building and Construction 3

Engineering Civil and Structural Engineering 3

General Engineering 2

Industrial and Manufacturing Engineering 2

Safety, Risk, Reliability and Quality 1

Aerospace Engineering 1

Automotive Engineering 1

Water Science and Technology 3 Environmental Ecology 1 Science General Environmental Science 1

35 Science and Innovation Audit Volume 2: Supporting Annexes

ME universities with distinctive Research area Subject area competencies in the subject area Health Physical Therapy, Sports Therapy and Professions Rehabilitation 6

Immunology 3 Immunology and Microbiology 1 Microbiology Virology 1

Polymers and Plastics 3

General Materials Science 3

Surfaces, Coatings and Films 1 Materials Science Materials Chemistry 1

Electronic, Optical and Magnetic Materials 1

Metals and Alloys 1

Applied Mathematics 4

Theoretical Computer Science 3

Mathematics General Mathematics 3

Modelling and Simulation 1

Statistics and Probability 1

Psychiatry and Mental Health 8

General Medicine 8

Orthopaedics and Sports Medicine 5

Public Health, Environmental and Occupational Health 4

Health Policy 4

Neurology (clinical) 4

Oncology 4

Rheumatology 3

Dermatology 3 Medicine Cardiology and Cardiovascular Medicine 3

Pulmonary and Respiratory Medicine 2

Pathology and Forensic Medicine 2

Paediatrics, Perinatology and Child Health 2

Endocrinology, Diabetes and Metabolism 2

Surgery 2

Gastroenterology 2

Obstetrics and Gynaecology 2

Infectious Diseases 1

36 Science and Innovation Audit Volume 2: Supporting Annexes

ME universities with distinctive Research area Subject area competencies in the subject area Family Practice 1

Anaesthesiology and Pain Medicine 1

Immunology and Allergy 1

Emergency Medicine 1

Epidemiology 1

Ophthalmology 1

Reproductive Medicine 1

Haematology 1

Transplantation 1

Sensory Systems 2

Neuroscience Behavioural Neuroscience 1

General Neuroscience 1

Community and Home Care 2

General Nursing 2 Nursing Leadership and Management 2

Nutrition and Dietetics 2

Pharmacology, Toxicology 1 Toxicology and Pharmaceutics Pharmacology 1

General Physics and Astronomy 5

Atomic and Molecular Physics, and Optics 5

Condensed Matter Physics 4 Physics and Astronomy and Astrophysics 3 Astronomy Acoustics and Ultrasonics 1

Nuclear and High Energy Physics 1

Statistical and Nonlinear Physics 1

General Psychology 10

Applied Psychology 5

Developmental and Educational Psychology 4 Psychology Social Psychology 3

Experimental and Cognitive Psychology 2

Clinical Psychology 1

General Social Sciences 12 Social Sciences Sociology and Political Science 11

37 Science and Innovation Audit Volume 2: Supporting Annexes

ME universities with distinctive Research area Subject area competencies in the subject area Education 10

Law 7

Political Science and International Relations 6

Library and Information Sciences 5

Geography, Planning and Development 4

Health (social science) 3

Cultural Studies 3

Linguistics and Language 3

Gender Studies 2

Social Sciences (miscellaneous) 1

Demography 1

Anthropology 1

Transportation 1

Communication 1

Veterinary General Veterinary 1

Emerging competencies

The Table below sets out the number of universities in the Midlands Engine 25 that have ‘emerging competences’ identified by Sci Val in the relevant research areas. The definition for emerging competencies as defined by Sci Val is provided below.

ME universities with emerging Research area Subject area competencies in the subject area Agronomy and Crop Science 5

Animal Science and Zoology 6

Aquatic Science 5

Ecology, Evolution, Behaviour and Systematics 11 Agricultural and Biological Food Science 6 Sciences General Agricultural and Biological Sciences 1

Horticulture 1

Plant Science 10

Soil Science 2

Archaeology (arts and humanities) 2 Arts and Humanities Arts and Humanities (miscellaneous) 2

38 Science and Innovation Audit Volume 2: Supporting Annexes

ME universities with emerging Research area Subject area competencies in the subject area Classics 4

General Arts and Humanities 20

History 17

History and Philosophy of Science 3

Language and Linguistics 6

Literature and Literary Theory 14

Music 3

Philosophy 10

Religious Studies 7

Visual Arts and Performing Arts 11

Aging 1

Biochemistry 9

Biotechnology 3

Cancer Research 6

Cell Biology 7 Biochemistry, Genetics and Developmental Biology 1 Molecular Biology Endocrinology 3

General Biochemistry, Genetics and Molecular Biology 3

Genetics 6

Molecular Biology 6

Physiology 3

Accounting 5

Business and International Management 12

General Business ,Management and Accounting 12

Management of Technology and Innovation 8 Business, Management Marketing 14 and Accounting Organizational Behaviour and Human Resource Management 10

Strategy and Management 17

Tourism, Leisure and Hospitality Management 8

Chemical Engineering General Chemical Engineering 4

Chemistry Analytical Chemistry 4

39 Science and Innovation Audit Volume 2: Supporting Annexes

ME universities with emerging Research area Subject area competencies in the subject area Electrochemistry 1

General Chemistry 9

Inorganic Chemistry 3

Organic Chemistry 7

Physical and Theoretical Chemistry 5

Spectroscopy 2

Artificial Intelligence 7

Computer Graphics and Computer-Aided Design 2

Computer Networks and Communications 14

Computer Science Applications 11 Computer Science Computer Vision and Pattern Recognition 4

General Computer Science 16

Human-Computer Interaction 7

Information Systems 8

Software 13

Decision Management Science and Operations Sciences Research 4

General Dentistry 4 Dentistry Periodontics 1

Atmospheric Science 5

Earth-Surface Processes 2

General Earth and Planetary Sciences 3

Geochemistry and Petrology 3

Geology 2 Earth and Planetary Geophysics 3 Sciences Geotechnical Engineering and Engineering Geology 2

Oceanography 2

Palaeontology 3

Space and Planetary Science 6

Economics and Econometrics 13 Economics, Finance 5 Econometrics and Finance General Economics, Econometrics and Finance 8

40 Science and Innovation Audit Volume 2: Supporting Annexes

ME universities with emerging Research area Subject area competencies in the subject area Energy Engineering and Power Technology 4

Fuel Technology 1 Energy General Energy 5

Renewable Energy, Sustainability and the Environment 6

Aerospace Engineering 3

Architecture 3

Automotive Engineering 2

Biomedical Engineering 4

Building and Construction 6

Civil and Structural Engineering 9

Control and Systems Engineering 11

Engineering Electrical and Electronic Engineering 16

Engineering (miscellaneous) 1

General Engineering 7

Industrial and Manufacturing Engineering 10

Mechanical Engineering 7

Mechanics of Materials 6

Ocean Engineering 1

Safety, Risk, Reliability and Quality 4

Ecology 5

Environmental Chemistry 3

Environmental Engineering 1

General Environmental Science 1 Environmental Health, Toxicology and Mutagenesis 1 Science Management, Monitoring, Policy and Law 3

Pollution 2

Waste Management and Disposal 2

Water Science and Technology 7

Occupational Therapy 2 Health Professions Physical Therapy, Sports Therapy and Rehabilitation 8

Applied Microbiology and Biotechnology 1 Immunology and Microbiology Immunology 8

41 Science and Innovation Audit Volume 2: Supporting Annexes

ME universities with emerging Research area Subject area competencies in the subject area Microbiology 3

Virology 1

Ceramics and Composites 3

Electronic, Optical and Magnetic Materials 6

General Materials Science 6 Materials Materials Chemistry 5 Science Metals and Alloys 1

Polymers and Plastics 6

Surfaces, Coatings and Films 2

Applied Mathematics 6

Computational Mathematics 1

Discrete Mathematics and Combinatorics 2

General Mathematics 4 Mathematics Mathematical Physics 2

Modelling and Simulation 1

Statistics and Probability 7

Theoretical Computer Science 5

Anaesthesiology and Pain Medicine 3

Cardiology and Cardiovascular Medicine 9

Complementary and Alternative Medicine 2

Critical Care and Intensive Care Medicine 1

Dermatology 7

Emergency Medicine 2

Endocrinology, Diabetes and Metabolism 11

Epidemiology 4

Medicine Family Practice 2

Gastroenterology 3

General Medicine 21

Genetics (clinical) 2

Geriatrics and Gerontology 5

Health Informatics 7

Health Policy 6

Haematology 2

Hepatology 1

42 Science and Innovation Audit Volume 2: Supporting Annexes

ME universities with emerging Research area Subject area competencies in the subject area Immunology and Allergy 4

Infectious Diseases 5

Internal Medicine 4

Medicine (miscellaneous) 1

Nephrology 5

Neurology (clinical) 11

Obstetrics and Gynaecology 5

Oncology 8

Ophthalmology 5

Orthopaedics and Sports Medicine 10

Otorhinolaryngology 1

Pathology and Forensic Medicine 5

Paediatrics, Perinatology and Child Health 7

Pharmacology (medical) 2

Psychiatry and Mental Health 15

Public Health, Environmental and Occupational Health 12

Pulmonary and Respiratory Medicine 5

Radiology, Nuclear Medicine and Imaging 3

Rehabilitation 1

Reproductive Medicine 2

Rheumatology 5

Surgery 7

Transplantation 2

Urology 1

Cellular and Molecular Neuroscience 1

Cognitive Neuroscience 6

Neuroscience General Neuroscience 9

Neurology 3

Sensory Systems 2

Community and Home Care 1

General Nursing 12 Nursing Gerontology 4

Maternity and Midwifery 2

43 Science and Innovation Audit Volume 2: Supporting Annexes

ME universities with emerging Research area Subject area competencies in the subject area Nursing (miscellaneous) 1

Nutrition and Dietetics 5

Pharmaceutical Science 9 Pharmacology, Toxicology and Pharmacology 6 Pharmaceutics Toxicology 3

Acoustics and Ultrasonics 7

Astronomy and Astrophysics 6

Atomic and Molecular Physics, and Optics 4

Condensed Matter Physics 10 Physics and Astronomy General Physics and Astronomy 6

Nuclear and High Energy Physics 4

Physics and Astronomy (miscellaneous) 1

Statistical and Nonlinear Physics 1

Applied Psychology 11

Clinical Psychology 5

Developmental and Educational Psychology 10

Psychology Experimental and Cognitive Psychology 7

General Psychology 12

Neuropsychology and Physiological Psychology 1

Social Psychology 4

Anthropology 3

Archaeology 3

Communication 11

Cultural Studies 12

Development 2

Education 22

Social Sciences Gender Studies 2

General Social Sciences 21

Geography, Planning and Development 16

Health (social science) 6

Human Factors and Ergonomics 3

Law 16

Library and Information Sciences 6

44 Science and Innovation Audit Volume 2: Supporting Annexes

ME universities with emerging Research area Subject area competencies in the subject area Linguistics and Language 11

Political Science and International Relations 9

Public Administration 3

Social Sciences (miscellaneous) 3

Sociology and Political Science 15

Transportation 5

Urban Studies 2

Veterinary General Veterinary 5

Definitions

Competencies represent research areas where an institution has obtained a leading position in terms of number of publications, number of highly cited publications or innovativeness – the recentness of cited publications. Eech competency is assigned to one or more ASJC journal categories (subject areas) based on the journal categories of the publication clusters that make up the competency. Each cluster competencies be classified as either distinctive or emerging competencies, depending on size of the field and whether or not the leadership criteria have been met.

To classify as distinctive a competency must meet the size criterion: it is a significantly large field of research. This means that the worldwide publication output in the field over the five- year period exceeds a specified threshold, related to the size of the institution/country. And it must also meet at least one of the three leadership criteria:

 the institution is ranked #1 worldwide in this field of research in terms of publication output

 the institution/country is ranked #1 worldwide in this field of research by number of highly cite publications.

 the institution/country is ranked #1 worldwide in this field of research in terms of innovativenes - the recentness of cited publications.

Competencies that do not meet the criteria for distinctive competencies are classified as emerging. Emerging competencies may not meet any of the criteria, or it may meet the field size criterion but not any of the leadership criteria, or it may meet at least one of the leadership criteria but not the size criterion.1

45 Science and Innovation Audit Volume 2: Supporting Annexes

Annex F: Long list of assets

F.1 The assets in the tables below are based on those identified in the initial Midlands Engine Science and Innovation Audit Expression of Interest, through work undertaken by the national contractor (Technopolis) as those organisations who have participated in collaborative research, with further assets that have been identified as part of the e-consultation exercise or through the workshop activity. Assets may be research facilities, innovative businesses, networks, science parks or incubators. It is not an exhaustive list and will not include all potentially relevant university activity unless identified in the process as discussed above. The universities in the Midlands Engine have instead been listed below.

Universities in the Midlands Engine Name LEP Aston University Greater Birmingham and Solihull

Birmingham City University Greater Birmingham and Solihull

Bishop Grosseteste University Greater Lincolnshire

Buckinghamshire New University South East Midlands

Coventry University Coventry and Warwickshire

Cranfield University South East Midlands

De Montfort University Leicester and Leicestershire

Harper Adams University The Marches

Keele University Stoke-on-Trent and Staffordshire

Loughborough University Leicester and Leicestershire

Newman University Greater Birmingham and Solihull

Nottingham Trent University Derby, Derbyshire, Nottingham and Nottinghamshire

Open University South East Midlands

Staffordshire University Stoke-on-Trent and Staffordshire

University College Birmingham Greater Birmingham and Solihull

University of Bedfordshire South East Midlands

University of Bedfordshire Milton Keynes South East Midlands

University of Birmingham Greater Birmingham and Solihull

University of Buckingham South East Midlands

University of Derby Derby, Derbyshire, Nottingham and Nottinghamshire

University of Leicester Leicester and Leicestershire

University of Lincoln Greater Lincolnshire

University of Northampton Northamptonshire

University of Nottingham Derby, Derbyshire, Nottingham and Nottinghamshire

46 Science and Innovation Audit Volume 2: Supporting Annexes

Name LEP University of Warwick Coventry and Warwickshire

University of Wolverhampton Black Country

University of Worcester Worcestershire Source: SQW

F.2 The Table below shows basic and applied research and commercialisation assets in the Midlands Engine. This includes university research centres and institutes, independent research and translation organisations (e.g. Catapult centres) and other research oriented organisations in both the public and private sectors.

47 Science and Innovation Audit Volume 2: Supporting Annexes

Basic and applied research and commercialisation

Name Location

Carbon Carbon

Medicine

Transport Transport

Advanced Advanced

Production

Engineering

Translational

Sciences and and Sciences

Digital Sector Digital Technologies Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Advanced Propulsion Centre (APC) Hub, University of Warwick Coventry x Agricultural Engineering Innovation Centre Telford and Wrekin x Agriculture and Horticulture Development Board Warwick x APC Spoke - Electrical Energy Storage, University of Warwick Coventry x APC Spoke - Power Electronics, University of Nottingham Nottingham x Arthritis Research UK Experimental Arthritis Treatment Centre, University of Birmingham x Birmingham Arthritis Research UK Pain Centre, University of Nottingham Nottingham x Arthritis Research UK Rheumatoid Arthritis Pathogenesis Centre of Excellence, Birmingham x University of Birmingham a partner Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis, led by Multi-site Nottingham University Hospitals NHS Trust, Universities of Loughborough and x Nottingham are partners Arthritis Research UK Centre for Tissue Engineering, Keele University a partner Newcastle-under-Lyme x Aston Brain Centre, University of Aston Birmingham x Birmingham Centre for Clinical Trials Birmingham x Birmingham Centre for Rail Research and Education, University of Birmingham Birmingham x Birmingham Institute of Translational Medicine Birmingham x British Geological Survey Rushcliffe x x British Hydromechanics Research Group Central Bedfordshire x Buckingham Institute for Translational Medicine, University of Buckingham Aylesbury Vale x Caterpillar Innovation and Research Centre, University of Loughborough Charnwood x Cenex - Centre of Excellence for Low Carbon and Fuel Cell technologies Charnwood x x

48 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Carbon Carbon

Medicine

Transport Transport

Advanced Advanced

Production

Engineering

Translational

Sciences and and Sciences

Digital Sector Digital Technologies Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Centre for Earth Observation & Instrumentation, University of Leicester Leicester x Centre for Patient Reported Outcome Research, University of Birmingham Birmingham x Centre for Sustainable Energy Use in Food, University of Birmingham Birmingham x Centre for Urban Agriculture, University of Nottingham Rushcliffe x Centre of Excellence for Telehealth and Assisted Living Aylesbury Vale x Creative Energy Homes, University of Nottingham Nottingham x Centre for Renewable Energy and Sustainable Technologies, University of Charnwood x Loughborough Cyber Security Centre of Excellence, University of Birmingham Birmingham x Institute of Creative Technologies, De Montfort University Leicester x Derby Clinical Trials Unit City of Derby x Design and New Product Development Centre, De Montfort University Leicester x Digital Heritage Hub, University of Birmingham Birmingham x Energy Research Accelerator Multi-site x Energy Systems Catapult Solihull x Energy Technologies Institute Charnwood x Engineering Materials Laboratory, Open University Milton Keynes x Enscite City of Derby x x Environment Agency Lichfield x EPSRC CDT in Additive Manufacturing & 3D Printing, Universities of Multi-site x Loughborough and Nottingham EPSRC CDT in Advanced and Targeted Therapeutics, University of Nottingham Nottingham x

49 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Carbon Carbon

Medicine

Transport Transport

Advanced Advanced

Production

Engineering

Translational

Sciences and and Sciences

Digital Sector Digital Technologies Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

EPSRC CDT in Carbon Capture and Storage and Cleaner Fossil Fuel Energy, Multi-site x Hosted by Universities of Birmingham, Loughborough and Nottingham EPSRC CDT in My Life in Data, University of Nottingham Nottingham x EPSRC CDT in Regenerative Medicine, Universities of Keele, Loughborough Multi-site x and Nottingham EPSRC CDT in Sustainable Materials and Manufacturing, Universities of Multi-site x x Warwick and Cranfield EPSRC Centre for Innovative Manufacturing in Food, Universities of Multi-site x Birmingham, Loughborough and Nottingham EPSRC CDT in Embedded Intelligence, Loughborough University Charnwood x EPSRC CDT in Engineering for the Water Sector, Cranfield University Central Bedfordshire x EPSRC CDT in Formulation Engineering, University of Birmingham Birmingham x EPSRC CDT in Fuel Cells and their Fuels, University of Birmingham Birmingham x EPSRC CDT in Physical Sciences for Health, University of Birmingham Birmingham x EPSRC CDT in Renewable Energy Marine Structures, Cranfield University Central Bedfordshire x European Association for Cancer Research Nottingham x European Bioenergy Research Institute, University of Aston Birmingham x Gas Turbine and Transmissions Research Centre, University of Nottingham Nottingham x Health Services Management Centre, University of Birmingham Birmingham x High Temperature Research Centre with Rolls-RoyceRolls-Royce, University of Birmingham x Birmingham Horizon Research Institute Nottingham x Institute of Energy and Sustainable Development, De Montfort University Leicester x Institute of Translational Medicine, University of Birmingham Birmingham x

50 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Carbon Carbon

Medicine

Transport Transport

Advanced Advanced

Production

Engineering

Translational

Sciences and and Sciences

Digital Sector Digital Technologies Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Laser Processing Facility, University of Loughborough Charnwood x Leicester Clinical Trials Unit Leicester x Lincoln Institute for Agri-Food Technology, University of Lincoln Lincoln x MRC Institute of Hearing Research Nottingham x MRC Toxicology Unit Leicester x MRC-Arthritis Research UK Centre for Musculoskeletal Ageing Research, Birmingham X University of Birmingham National Centre for Earth Observation, University of Leicester Leicester x National Centre for Food Manufacturing, University of Lincoln South Holland x National Centre for Precision Farming, Harper Adams University Telford and Wrekin x National Centre for Sport and Exercise Medicine, University of Loughborough Charnwood x National Energy Foundation Milton Keynes x National Space Centre Leicester x Network Rail's Rail Innovation and Development Centre Multi-site x NIHR Birmingham Liver Biomedical Research Unit Birmingham x NIHR Leicester Cardiovascular Biomedical Research Unit Leicester x NIHR Leicester Respiratory Biomedical Research Unit Leicester x NIHR Leicester-Loughborough Diet, Lifestyle and Physical Activity Biomedical Leicester x Research Unit NIHR Nottingham Digestive Diseases Biomedical Research Unit Nottingham x NIHR Nottingham Hearing Biomedical Research Unit Nottingham x NIHR Surgical Reconstruction and Microbiology Research Centre Birmingham x Northfield Eco Centre Birmingham x

51 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Carbon Carbon

Medicine

Transport Transport

Advanced Advanced

Production

Engineering

Translational

Sciences and and Sciences

Digital Sector Digital Technologies Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Nottingham Geospatial Institute, University of Nottingham Nottingham x PERA Technology Melton x Perinatal Institute Birmingham x Precision Medicine Institute, University of Leicester Leicester x Public Health England Nottingham x Research Centre for Museums and Galleries, University of Leicester Leicester x Share Energy Shropshire x Smart Energy Network Demonstrator, Keele University Newcastle-under-Lyme x Space Research Centre, University of Cranfield Central Bedfordshire x Space Research Centre, University of Leicester Leicester x Tech Mahindra Milton Keynes x Transport Systems Catapult Milton Keynes x UK Health and Environment Research Institute Melton x UK Quantum Technology Hub for Sensors and Metrology, University of Birmingham x Birmingham Warwick Clinical Trials Unit Coventry x Wellcome Clinical Research Facility Birmingham x West Midlands Genomics Medicine Centre - x Willenhall Battery Storage Test Facility Walsall x

F.3 The table below shows further healthcare assets, including hospitals, NHS Trusts and major trauma centres. As they are all healthcare assets, the Thematic Area columns have been removed from this table.

52 Science and Innovation Audit Volume 2: Supporting Annexes

Healthcare assets

Name Location Birmingham and Midland Eye Centre Birmingham Birmingham and Solihull Mental Health NHS Foundation Trust Birmingham Birmingham Centre for Clinical Haematology Birmingham Birmingham Children's Hospital - Children Major Trauma Centre Birmingham Birmingham City Hospital Birmingham Birmingham Community Healthcare NHS Trust Birmingham Birmingham Women's Hospital Birmingham Chesterfield Royal Hospital NHS Foundation Trust Chesterfield Derby Hospitals NHS Foundation Trust City of Derby George Eliot Hospital Nuneaton and Bedworth Glenfield Hospital Leicester Haywood Hospital City of Stoke-on-Trent Heart of England NHS Foundation Trust Birmingham Leicester General Hospital Leicester Leicester Royal Infirmary Leicester Lincoln County Hospital Lincoln London Road Community Hospital City of Derby Luton and Dunstable Hospital Luton Meriden Hospital Coventry Midland Eye Solihull Milton Keynes Hospital NHS Foundation Trust Milton Keynes New Cross Hospital City of Wolverhampton North Staffordshire Combined Healthcare NHS Trust City of Stoke-on-Trent Northampton General Hospital Northampton Nottingham City Hospital Nottingham Nottingham University Hospitals NHS Trust Nottingham

53 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location Nottinghamshire Healthcare NHS Foundation Trust Nottingham Queen Elizabeth Hospital - Adult Major Trauma Centre Birmingham Queens Medical Centre, Nottingham - Adult and Children Major Trauma Centre Nottingham Robert Jones and Agnes Hunt Orthopaedic Hospital Shropshire Royal Buckinghamshire Hospital Aylesbury Vale Royal Centre for Defence Medicine Birmingham Royal Derby Hospital City of Derby Royal Orthopaedic Hospital Birmingham Royal Stoke University Hospital City of Stoke-on-Trent Sandwell & West Birmingham Hospitals NHS Trust Sandwell South Essex Partnership University Foundation NHS Trust Luton St George's Hospital Stafford Stoke Mandeville Hospital Aylesbury Vale University Hospital Coventry - Adult Major Trauma Centre Coventry University Hospital of North Staffordshire - Adult Major Trauma Centre City of Stoke-on-Trent University Hospitals Birmingham NHS Foundation Trust Birmingham University Hospitals Coventry and Warwickshire NHS Trust Coventry University Hospitals of Leicester NHS Trust Leicester Walsall Manor Hospital Walsall Warwickshire Hospital Warwick Worcester Royal Infirmary Worcester Worcestershire Acute Hospitals NHS Trust Redditch

F.4 The table below shows industrial assets in the Midlands Engine, ranging from large, multinational businesses to innovative SMEs and start-ups.

54 Science and Innovation Audit Volume 2: Supporting Annexes

Industrial assets

Name Location

Transport Transport

Advanced Advanced

Production

Engineering

Sciences and and Sciences

Digital Sector Digital Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Carbon Technologies Carbon

Translational Medicine Translational

2 Sisters Food Group (inc. Technical Services and Microbiology Laboratory) Multi-site x 3M Multi-site x

3SDL Malvern Hills x

ABB - Smart Grid Base Stafford x

Act on Energy Stratford-on-Avon x

Added Scientific Nottingham x

Adelan Birmingham x

AGCO Warwick x

Agco Warwick x

Aggregate Industries Blaby x

Agricultural Development Advisory Service City of Wolverhampton x

Airbus Defence and Space Blaby x

Airbus Services Blaby x

Aircraft Research Association Bedford x

Alliance Medical Warwick x

Allinea Software Warwick x

Alstom Transportation Multi-site x

Amey - x

APP institute Nottingham x

Arden Photonics Solihull x

Arla Foods Melton x

55 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Transport Transport

Advanced Advanced

Production

Engineering

Sciences and and Sciences

Digital Sector Digital Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Carbon Technologies Carbon

Translational Medicine Translational

Aston Eye Tech Birmingham x

Aston Martin Stratford-on-Avon x

Astra Zeneca Luton x

AVL Powertrain Coventry x

Axes Design Malvern Hills x

Axillium Research Daventry x

Bakkavor South Holland x

Barum & Dewar City of Derby x

Basic Thinking Leicester x

BBR Optometry County of Herefordshire x

Belvoir Fruit Farms Melton x

Beth Johnson Foundation City of Stoke-on-Trent x

Birmingham Optical Birmingham x x

Bladon Jets Coventry x

Blue Bear Bedford x

Blueprint Nottingham x

Bluesky Aerial Photography North West Leicestershire x

Bombardier City of Derby x

Boots Nottingham x

Borwell Malvern Hills x

Bosch Thermotechnology Worcester x

56 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Transport Transport

Advanced Advanced

Production

Engineering

Sciences and and Sciences

Digital Sector Digital Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Carbon Technologies Carbon

Translational Medicine Translational

Branston North Kesteven x

Brealey Aviation North East Derbyshire x

British Gas Blaby x

British Sugar Newark and Sherwood x

Brunei Halal Birmingham x

Brush Traction Charnwood x

Bulb Studios Leicester x

Business Council for Sustainable Development UK Sandwell x x

Calor Gas Warwick x

Campden BRI Warwick x

Capital One Nottingham x

Capula Stafford x

Caterpillar Hinckley and Bosworth x

Charnwood Molecular Charnwood x

Chartered Institution of Wastes Management Northampton x

Cherry Valley West Lindsey x

Clear Communication Associates Milton Keynes x

Cobra Biologics Newcastle-under-Lyme x

Co-Fresh Snack Foods Leicester x

Cooke Optics Charnwood x

Co-operative Energy Warwick x

57 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Transport Transport

Advanced Advanced

Production

Engineering

Sciences and and Sciences

Digital Sector Digital Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Carbon Technologies Carbon

Translational Medicine Translational

Core Diagnostics Birmingham x

Cosworth Northampton x

Coveris West Lindsey x

Cummins Wellingborough x

Cuttlefish Charnwood x

Dairy Crest Food Innovation Centre Telford and Wrekin x

Datalink Electronics Charnwood x

Deep-Secure Malvern Hills x

Delcam Birmingham x

Delta Rail City of Derby x

DNV GL Charnwood x

Dolphin Computer Access Worcester x

Doncasters Group East Staffordshire x

Donnington cluster North West Leicestershire x

Droplet Birmingham x

Dunelm Charnwood x

E.ON Coventry x

East End Foods Sandwell x

EkkoSense Nottingham x x

Encraft Warwick x

Engie Solihull x

58 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Transport Transport

Advanced Advanced

Production

Engineering

Sciences and and Sciences

Digital Sector Digital Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Carbon Technologies Carbon

Translational Medicine Translational

European Thermodynamics Harborough x

Evance Wind Turbines Charnwood x

Everards Brewery Blaby x

Experian Nottingham x

Farsan Foods Leicester x

Fashion Fabrics Transprinters Leicester x

First Midland Red Worcester x

First Utility Warwick x

Fox's Biscuits East Staffordshire x

Future Water Association Warwick x x

Gas Data Coventry x

GE (inc. Grid Solutions, Power Conversion, Sensing) Multi-site x

GKN Multi-site x x x

Greencore Bolsover x

Haley Sharpe Design Leicester x

Haydale Composite Solutions (formerly EPL Composite Solutions) Charnwood x

HORIBA MIRA Hinckley and Bosworth x x x

IBM Multi-site x

Impact Engineering . North Kesteven x

Industrial Control Solutions Bassetlaw x

Intelligent Energy Charnwood x

59 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Transport Transport

Advanced Advanced

Production

Engineering

Sciences and and Sciences

Digital Sector Digital Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Carbon Technologies Carbon

Translational Medicine Translational

ITP Birmingham x

IXC Birmingham x

Jadu Blaby x

Jaguar Land Rover Multi-site x

JCB East Staffordshire x x x

JDM foods Boston x

John Bowler Energy South Derbyshire x x

Juniper Pharma Services (formerly Molecular Profiles) Nottingham x

Just Egg Leicester x

Laing O'Rourke - Explore Manufacturing Facility Bassetlaw x

Limagrain West Lindsey x

Lindhurst Engineering Ashfield x

Linear Diagnostics Birmingham x

Lockheed Martin Multi-site x

Lucideon City of Stoke-on-Trent x

Magna Parva Leicester x

Manufacturing Technology Centre (HVMC) Rugby x

Meesha Graphics Leicester x

Meggit Aircraft Braking Systems Coventry x

Mercedes AMG Petronas F1 Team South Northamptonshire x

Microlise Broxtowe x

60 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Transport Transport

Advanced Advanced

Production

Engineering

Sciences and and Sciences

Digital Sector Digital Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Carbon Technologies Carbon

Translational Medicine Translational

Molson Coors East Staffordshire x

Mondelez Global Centre for Chocolate Research and Development Birmingham x

Monica Healthcare Erewash x

Moog Space and Defence Group, and Aircraft Group Multi-site x

Morgan Motor Company Malvern Hills x

Morningside Pharmaceuticals Charnwood x

Motor Design Shropshire x

Motor Neurone Disease Association Northampton x

Moy Park North Kesteven x

MWUK North West Leicestershire x

National Farmers Union Warwick x

National Grid Newark and Sherwood x

Nestle South Derbyshire x

NetComposites Enterprise Chesterfield x

Newlife Foundation for Disabled Children Cannock Chase x

Next Blaby x x

Niche Vehicle Network Charnwood x

Nissan Technical Centre Central Bedfordshire x

Nottingham Creative Quarter Nottingham x

Nova Laboratories Oadby and Wigston x x

NPD Direct South Holland x

61 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Transport Transport

Advanced Advanced

Production

Engineering

Sciences and and Sciences

Digital Sector Digital Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Carbon Technologies Carbon

Translational Medicine Translational nPower East Staffordshire x x

NuVision Broxtowe x

OCB Media Leicester x

Ocean Power Technologies Warwick x

Ofwat Birmingham x

Optimec Malvern Hills x

Optimus Energy Birmingham x

Ortelio Coventry x x

Oxford Medical Diagnostics Cherwell x

PCA Engineers West Lindsey x

Pentair Harborough x

PepsiCo Leicester x

Perkins Engines Stafford x

Pharminox Nottingham x

Pick Everard Leicester x

Platelet Solutions Nottingham x

Porterbrook City of Derby x

Prescient Power North West Leicestershire x x

Prodrive Milton Keynes x

Produce World South Holland x x x

Prolysis Cherwell x x x

62 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Transport Transport

Advanced Advanced

Production

Engineering

Sciences and and Sciences

Digital Sector Digital Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Carbon Technologies Carbon

Translational Medicine Translational

Qinetiq Malvern Hills x

Quest Biomedical Solihull x

Quest Healthcare Birmingham x

Quotient Clinical Rushcliffe x x

Randle Engineering Solutions Warwick x

Rare Games Hinckley and Bosworth x

Reaction Engines Aylesbury Vale x

Ricardo 's Midlands Technical Centre Warwick x

Robin Hood Energy Nottingham x

Rolls-Royce City of Derby x

Romax Technology Nottingham x

Royal Tea Leicester x

RPC Bebo Corby x

RPS Environmental Management City of Derby x

SAIC Motor Corporation - UK Technical Centre Birmingham x

Samworth Brothers Melton x

SCC Birmingham x

Schueco Milton Keynes x

Semelab Harborough x

Sensory Dimensions Nottingham x

Serascience Nottingham x

63 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Transport Transport

Advanced Advanced

Production

Engineering

Sciences and and Sciences

Digital Sector Digital Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Carbon Technologies Carbon

Translational Medicine Translational

Severn Trent Coventry x

Shima Seiki Demonstration Facility North West Leicestershire x

Siemens Multi-site x

Silverstone cluster South Northamptonshire x

Smithers Rapra Shropshire x

SNC-Lavalin Croydon London Boro x

Solway Foods Bassetlaw x

Source Bioscience Nottingham x

SterlingGEO Charnwood x

Stroke Association Nottingham x

Sygnature Discovery Nottingham x

Syncreon Technology UK Hinckley and Bosworth x

T H Clements Boston x

Tata Steel R&D Facility Coventry x

Taylor Hobson Leicester x

TBAT Innovation North West Leicestershire x

TDP Textiles North West Leicestershire x

TDX Group Nottingham x

Tech4i2 Leicester x

Technical Software Consulting Milton Keynes x

Teer Coatings Wychavon x

64 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Transport Transport

Advanced Advanced

Production

Engineering

Sciences and and Sciences

Digital Sector Digital Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Carbon Technologies Carbon

Translational Medicine Translational

Tetenal Blaby x

The Binding Site Birmingham x

Thea Pharmaceuticals Newcastle-under-Lyme x

Thermo Fisher Charnwood x

Thorntons Amber Valley x

Titania Worcester x

Toyota South Derbyshire x x

Tracsis City of Derby x

Triumph Motorcycles Hinckley and Bosworth x x

Unilever Bedford x

Uniper Technologies - R&D and Engineering Academy Rushcliffe x x

URGO Charnwood x

UTC Aerospace Systems (Formerly Goodrich) City of Wolverhampton x

Velan Valves Charnwood x

Veolia Birmingham x

Vinola Knitwear Leicester x

ViVO Smart Broxtowe x

Walkers Snack Food Leicester x

Warwick Manufacturing Group (HVMC) Coventry x

Weetabix Kettering x

Weiss Technik Charnwood x x x

65 Science and Innovation Audit Volume 2: Supporting Annexes

Name Location

Transport Transport

Advanced Advanced

Production

Engineering

Sciences and and Sciences

Digital Sector Digital Technologies

food and Drink and Drink food

-

Healthcare, Life Life Healthcare,

Energy and Low Low Energy and

Manufacturing and and Manufacturing and Manufacturing

Agri

Creative, Design and and Design Creative,

Carbon Technologies Carbon

Translational Medicine Translational

Western Power Distribution Sandwell x

Westfield Sports Cars Dudley x x

Whisk Birmingham x

Yamazaki Mazak Worcester x x

Young's Seafood North East Lincolnshire x

F.5 The table below shows networks that Midlands Engine partners participate in. These include international networks as well as networks at a pan Midlands Engine, East/West Midlands, LEP or city level.

Networks

Name

Low Low

Drink Drink

Carbon Carbon

food and food

Medicine

-

Transport Transport

Advanced Advanced

Production

Engineering

Translational Translational

Sciences and and Sciences

Technologies Technologies

Agri

Healthcare, Life Life Healthcare,

Energy and

Creative, Design Design Creative,

and Digital Sector and Digital

Manufacturing and and Manufacturing and Manufacturing

East Midlands Academic Health Science Network x

European Powder Metallurgy Association x

Marches Energy Agency x

Midlands Energy Consortium x

Notts Energy Partnership x

Sustainability West Midlands x

66 Science and Innovation Audit Volume 2: Supporting Annexes

Name

Low Low

Drink Drink

Carbon Carbon

food and food

Medicine

-

Transport Transport

Advanced Advanced

Production

Engineering

Translational Translational

Sciences and and Sciences

Technologies Technologies

Agri

Healthcare, Life Life Healthcare,

Energy and

Creative, Design Design Creative,

and Digital Sector and Digital

Manufacturing and and Manufacturing and Manufacturing

West Midlands Academic Health Science Network x

Alan Turing institute - partner x

Birmingham Health Partners x

Birmingham Smart City Alliance x

Black Country Manufacturing Club x

Design Start DTP (participation in) x

EIT Climate-KIC x

EIT Health KIC x

Food and Drink Forum x

Ingenuity Network x

Medilink East Midlands x

Medilink West Midlands x

Midlands Aerospace Alliance x x

Midlands Three Cities Doctoral Training Partnership x

MK Energy Club x MK Smart x

Nottingham Manufacturing Network x

Nottinghamshire Manufacturing Network x

Rail Forum East Midlands x

Collaboration for Leadership in Applied Health Research and Care West Midlands x

67 Science and Innovation Audit Volume 2: Supporting Annexes

Annex G: Case examples

G.1 Case examples have been developed through the SIA process to provide examples of practical innovation activity across the Midlands Engine, focused on activity in the four Market-Driven Priority areas. The case examples cover a mix of profiles of individual firms, and examples of collaborative R&D and innovation activity undertaken in the region.

68 Science and Innovation Audit Volume 2: Supporting Annexes

Next Generation Transport

Jaguar Land Rover

Background

With over 35,000 staff, JLR is the largest automotive employer in the UK, and its only volume manufacturer of luxury vehicles. JLR employs 35,000 people in the UK, including over 9,000 engineers and designers, and is the largest investor in automotive R&D and engineering in the UK.

Profile and innovation offer

A global business, with over 80% of its production exported and sales networks in over 150 countries, JLR is also a Midlands Engine global success story, with an extensive network of sites across the UK, with a particular concentration in the Midlands Engine region, as illustrated below.

Investment in innovation

JLR’s major recent investments into the Midlands Engine include:

 the new £20m Special Vehicle Operations Technical Centre in Ryton, near Coventry; this is JLR’s global centre of excellence for the creation of high-end luxury bespoke and extreme performance vehicles, with a team of 150 JLR specialists based at Ryton

 the £1bn UK Engine Manufacturing Centre in Wolverhampton, this began production early 2015, with in-house development and manufacture of 4-cylinder petrol and diesel engines. Jaguar XE and Discovery Sport first vehicles to have Ingenium engine

 and with the Warwick Manufacturing Group and Tata Motors European Technical Centre, JLR has invested in the £150m National Automotive Innovation Centre (NAIC), which will open in 2017, providing a state-of-the-art facility for collaborative R&D.

69 Science and Innovation Audit Volume 2: Supporting Annexes

Rolls-Royce

Background

Rolls-Royce has been at the forefront of engineering in the UK for over 100 years. The firm directly employs around 24,500 people across the UK across its business units, and has a significant presence in Derby. Derby is where the firm designs, assembles and test the Trent jet engines, and the production hub for the Trent XWB – the world’s most efficient large aero engine that powers the Airbus A350 XWB. Rolls-Royce’s submarines business that powers the UK's Royal Navy submarine fleet is also based in Derby, and supported across UK naval bases, and the firm’s Apprentice Academy is based in the city.

Engagement in innovation across the Midlands

Rolls-Royce works extensively with science and innovation assets across the region, for example:

Harsh Environment Electronics Demonstrator Project: Rolls-Royce subsidiary Control & Data Systems (CDS) partnered with a range of defence, electronics and aerospace companies and the Manufacturing Technology Centre in Coventry to develop and demonstrate new electronics components and assembly methods capable of withstanding very harsh environments. This work will enable engine electronics to survive closer to the parts of the engine they are controlling or monitoring, reducing the length and weight of connecting wiring and harnesses and allowing better control and packaging of the engine as a whole. The MTC has been researching new joining methods and demonstrating them on industrial scale equipment so that they can be deployed in real products. This and other technologies developed collaboratively through this project will be deployed in future engines and also have potential in many other applications where harsh environments exist (e.g. oil & gas exploration).

‘Fast Make’ manufacturing methods project: Rolls-Royce partnered with a wide range of university and industry collaborators to develop rapid manufacturing technologies that significantly reduce the lead time for producing development components. Fast make methods allow the shortening of development timescale and/or increased improvement iterations in the same elapsed time. The MTC has helped develop automated coordinate measuring machine programming methods that allow development parts to be quickly verified and has captured the process for achieving this in a best practice guide for wider use. Birmingham University has pioneered novel methods of manufacturing ceramic turbine casting cores that reduce lead times by 25% and formed a long term partnership with Rolls-Royce on advanced high temperature materials resulting in a state of the art High Temperature Research Centre adjacent to the MTC: this proximity encourages collaboration in bringing early stage science and technology developed with the university up to industrial readiness and on to future deployment.

Future combustion systems research and University Technology Centres: Rolls-Royce partnered with Loughborough University to research lean burn combustion for future aero engines. This collaboration has included the donation by Rolls-Royce of a test rig and its installation and upgrading in Loughborough to carry out advanced testing and research for a range of purposes including teaching. This is an example of the long term partnering between Rolls-Royce and Universities across the region in University Technology Centres that carry out research, develop skills and provide a path for academic excellence to be translated into industrially relevant technology and product innovation. Rolls-Royce has 19 such centres in the UK with 5 in the Midlands Engine region (Nottingham x2, Loughborough, Birmingham and Cranfield).

70 Science and Innovation Audit Volume 2: Supporting Annexes

Future Food Processing

Olympus Automation (OAL)

Background

OAL is a well-established food automation and engineering company, which whilst based just outside the ME region in Peterborough, has much of its client base in the ME food processing sector and a strategic applied research base at the Nation Centre for Food Manufacturing in Holbeach to develop new food processing technologies.

Profile and innovation offer

OAL is committed to supporting food processing improvement though programs of holistic innovation across four connected themes: eliminating waste; improving product quality; ensuring food safety and traceability; offering manufacturing flexibility. Since 2012 it has increased investment in R&D to in excess of 8.2% of turnover to innovate food production systems and technologies.

OAL is working closely with NCFM to revolutionise the future of food processing through a number of Innovate UK and privately funded applied research programmes. These programmes are all designed to automate food processing or to make it more cost and environmentally efficient. Key projects include:

Steam Infusion cooking: generation of health and flavour benefits for food products through a disruptive steam cooking process;

APRIL: Automated Processing Robotic Ingredient Loading, is a new robotic industrial scale ‘chef’ system which allows fully automated ingredient mixing and cooking in one tonne batches using state of the art robotics. It was launched in April 2016 and has won numerous awards and attracted global attention. The work with NCFM is ensuring that this new technology can handle liquids and dry ingredients, cooking processes and hygiene issues in a food factory environment using industry standard robotics.

The future

With its systems delivering cost and labour savings, whilst improving quality and consistency OAL is finding a ready market for its technologies both in the UK and overseas with food processors such as Greencore, Bakkavor, 2SFG, AAK and Larco Foods.

Given its focus on labour efficiency the introduction of the NLW will drive increased demand for its technologies, such as APRIL, in the UK and technologies such Steam Infusion Cooking will benefit from an industry focus on both cost reduction (e.g. energy use) and new cooking technologies which can increase product quality.

71 Science and Innovation Audit Volume 2: Supporting Annexes

Festo

Background

Festo is a global company which specialises in industrial and process automation. It has an Applied Automation Centre in Brackmills, Northampton and works across the UK with a range of industries including specialist services for the food manufacturing sector as well as other Midlands Engine key sectors such as automotive.

Profile and innovation offer

Festo provides a wide range of technology solutions which promote process efficiency in food manufacturing whilst also being easy to clean to safeguard food safety. It is focused on innovation through the introduction of new technology solutions and during 2016 has already introduced new products for food manufacturing in six areas:

 Pneumatic drives

 Electric drives and handling systems

 Valves and valve terminals

 Compressed air preparation and connection technology

 Sensors and vision systems

 Process automation

Addressing the specific challenges of introducing automation into food processing, such as the potential contamination of food products by machinery or compressed air and the need for hygienic design, so that production lines are easy to clean between batches, are at the heart of the technology solutions which Festo develops and supplies to the food industry.

Festo is also committed to supporting the food manufacturing sector via the provision of specialist training services and has worked with the National Centre for Food Manufacturing on further education provision for the food industry. It takes on apprentices every year to ensure that it can support its technology offer with new talent and has been very active in promoting the innovation and technology career prospects in the food sector alongside other major food industry partners.

The future

Festo provides its automation and training services both in the UK and overseas to food processors and expects to see demand grow as the World tries to meet the demand for more food and the increased demand for processed foods in particular. Festo believes that its growth prospects are strong if it can match its investment in new products with a continued programme of skills development to ensure that the food industry has the engineers needed to design, install and maintain automation solutions. Its base in the Midlands is ideally placed to serve the UK’s food industry and its future growth.

72 Science and Innovation Audit Volume 2: Supporting Annexes

ACO

Background

ACO Technologies plc operates from two sites based at Shefford and Bedford in Bedfordshire. It is part of the global ACO Group which operates across five continents and employs 4,200 staff. It specialises in surface water management inside buildings - such as food factories - and in the outside environment for roads, car parks, roofs and other hard surfaces.

Profile and innovation offer

ACO has been innovating in the management of water for over 50 years and has a global R&D team which develops innovative water management products for use in many different industries.

One sector of focus is food and drink manufacturing. The manufacturing environments are often wet and require the efficient management and removal of waste water. This is essential both for health and safety of the workforce and for food quality and hygiene to protect the public. The development of modern hygienic drainage systems has been a key development for the group over the last few years.

Water is used as an ingredient in food and drink, but many manufacturing processes lead to large quantities of waste water which can be contaminated with a wide range of pollutants and harmful pathogens. For example, the fresh produce sector, in which the Midlands region specialises, routinely uses water to clean products before and during processing. Food processing can also contaminate waste water with fats and grease, which unless captured quickly block drainage systems and cause major food hygiene problems.

Effective drainage systems in food and drink manufacturing environments also need to be able to cope with cleaning chemicals and detergents which are used to wash down food processing lines either as part of routine hygiene regimes or between batches and must themselves be easy to clean and robust enough to cope with the challenging environment in a food factory. Working closely with food companies and industry experts to specify and design innovative water management systems, ACO offers highly engineered products alongside a bespoke design service to help companies select the right technologies for their particular factory environment.

The future

Alongside the key issue of hygiene, the management of water in the food industry has been rising up the agenda with the Food and Drink Federation working with leading food companies to reduce water use in food processing. In the first five years since 2010, their Federation House Commitment managed to reduce water used per tonne by 26%. With 47% of the world’s population projected to be living in areas under water stress by 2030, food companies are very conscious of the need to improve their management of water resources. ACO products can play a key role in ensuring future water management meets the needs of the growth in the food industry.

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Medical Technologies and Pharmaceuticals

The Binding Site

Background

Founded by researchers at the University of Birmingham, Binding Site has continued to grow through a focus on research and development in the field of immunodiagnostic assays & instrumentation. Its sole manufacturing facility is based at head office in Edgbaston, Birmingham, and all products are distributed from there. It is now represented in almost 100 countries, with an annual turnover exceeding £80m and employing almost 800 people, 500 of whom are in the UK.

Profile and innovation offer

The Binding Site researches, develops, manufactures and distributes specialist immunodiagnostic assays & instrumentation, providing specialist diagnostic products to clinicians and laboratory professionals worldwide. Its primary focus is on certain blood cancers and disorders of the immune system. Managed from its Birmingham HQ, the company continues to have strong links with the University of Birmingham and other local research centres, as well as universities and research institutions in dozens of countries around the globe.

Binding Site is the world leader in diagnostic testing for the blood cancer, Multiple Myeloma. It’s highly specific and sensitive polyclonal test, Freelite©, is used to accurately detect and monitor B-cell dyscrasias such as myeloma. It now offers a menu of over 200 diagnostic assays across a range of clinical diagnostic systems and sells well over 30 million tests per year, over 90% of which go to laboratories and hospitals overseas.

The future

The company continues to expand geographically, having offices with direct customer contact in approximately 20 countries as well as a network of distributors managed directly by dedicated Binding Site staff. With an enviable record of consistent double digit sales growth, Binding Site sets itself ambitious targets, continuing to explore and challenge the status quo in diagnosing and monitoring treatment of myeloma and related B-Cell diseases as well as disorders of the immune system and vaccine responses.

There are multiple research and collaboration projects on-going at any one time, though one recent highlight was the company’s was selection as the Diagnostic collaborator for a population-wide screening study, the first of its kind, in Iceland starting this year. The iStopMM (Iceland Screens, Treats or Prevents Multiple Myeloma) trial is considered a pivotal trial in the understanding of this currently treatable but incurable disease.

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University of Leicester and GSK collaboration

Background

A collaboration between the University of Leicester and global pharmaceutical company GlaxoSmithKline (GSK) has been established (in 2016) to discover and develop novel medicines to treat aggressive forms of blood cancer.

High grade non-Hodgkin’s lymphoma is one of the most common forms of blood cancer, with more than 5,000 new cases reported each year in the UK. The new project is part of GSK’s Discovery Partnerships with Academia (DPAc) initiative, which brings together the insight and creativity of world-leading academics with the drug discovery expertise of GSK to create new medicines and bring them to the clinic. Launched in the UK in late 2010, DPAc is a new approach to drug discovery that enables academics to marry their scientific excellence with the drug discovery insight of GSK. GSK and the academic collaborator share the challenges and rewards of innovation; GSK provides drug discovery expertise and in-kind resources as well as funding activities in the academic laboratories to progress a programme from idea to candidate medicine.

Project aims and activity

The aim of the project is to discover and develop new molecules that can make a clinical impact in the treatment of patients with high grade non-Hodgkin’s lymphoma.

The new collaboration builds upon a previous GSK Discovery Fast Track Challenge project, which was awarded to Professor Wagner from the Department of Cancer Studies at Leicester University, whyo will lead on the new collaboration, in December 2014 and was amongst the first projects of its type to launch in Europe.

Under the terms of the new agreement, the University will receive success-based financial support from GSK upon the achievement of key milestones, as well as an upfront payment and royalties on sales from any product that is successfully commercialised out of the collaboration.

Leicester Drug Discovery and Diagnostics Centre (LD3) that will host the collaboration, works with academics and clinicians from the University of Leicester to initiate and sustain drug and diagnostic discovery programmes arising from world class fundamental research at the University. The Centre forms a core facility within the College of Medicine, Biological Sciences and Psychology and both the Leicester Precision Medicine Institute and Leicester Institute of Structural and Chemical Biology.

LD3 also works closely with Clinical Academics from the University Hospitals of Leicester NHS Trust enabling access to patients and patient samples. The Trust hosts three NIHR Biomedical Research Units in i) Cardiovascular, ii) Respiratory; and iii) Diet, Lifestyle and Physical Activity. Our spectrum of clinical research activity also includes an Experimental Cancer Medicine Centre, CRUK Cancer Research Centre, a wide portfolio of clinical trials and an accredited Clinical Trials Unit.

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Energy and Low Carbon

The Energy Research Accelerator

Background

Energy research and, in particular, battery research has been an area of significant expertise for the University of Warwick for many years. Over the last ten years Warwick Manufacturing Group (WMG), an academic department at the University, has developed the Energy Innovation Centre (EIC). The EIC includes a £13m Battery Material Scale-Up Pilot Line, supported through the UK Automotive Council, which provides a one-stop-shop for the development of new battery chemistries from concept to fully proven traction batteries, available in sufficient quantities for industrial scale testing. The Centre also includes a battery characterisation laboratory, aggressive testing chambers and an electric/hybrid drives test facility. This unique UK facility, which has integrated capital investments through Science City and the High Value Manufacturing Catapult, will benefit from significantly expanded capability through ERA investment. The EIC has proved to be invaluable to both the UK transport and the UK energy sector, enabling a great deal of collaborative research with large multi-nationals including TATA, JCB and Nissan, the motorsport, rail and marine sectors, as well as large numbers of local SMEs. Warwick’s research in this area is closely associated with other leading academic institutions and their collaboration with the University of Oxford has led to both groups furthering their contributions to battery development. WMG’s role in the fundamental development of Li-ion batteries and their application in buses and cars has led to a major demonstration of this leading edge technology.The EIC has specifically helped Wrightbus evaluate the real-world in-service performance of the battery packs for their prototype fleet, and characterise the electrical and thermal performance of an experimental battery pack.

Innovation activity in the Midlands

In 2012 the first revolutionary Routemaster (New Bus for London) hybrid diesel-electric buses manufactured by Wrightbus entered service in London. The No.24 bus route in London passes major sights of the city including the Houses of Parliament and Trafalgar Square. Given the locations that the bus route passes through, it is of no surprise that it suffers heavily from traffic congestion. Consequently, the route was chosen as a ‘design route’ which would help evaluate the capability of batteries to power the bus around the capital. Over the course of a typical day a bus on the No.24 route will have to stop and start up to 3000 times - a particularly challenging cycle for any battery technology

Using a real-world drive cycle based on data from the actual London bus route, and a 250kW high performance battery pack cycling system, the performance of in-service battery packs was tested and characterised at the EIC, so it could be evaluated against the original design parameters. A long duration accelerated life-cycle ageing test was completed to evaluate the performance of an experimental battery pack.

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Fast forward to 2016 and implementation has been extended to 600 London buses which represents nearly 10% of the entire London fleet; making a significant contribution to the reduction of noxious gases in the area and improving the air quality for citizens.

The future

Interest in this technology is growing in cities across the UK and internationally. It is an excellent example of academia working closely with industry to take a technology through the difficult Technology Readiness Level stages (4-6). Bridging the so called ‘Valley of Death’ across these levels is critical to increasing and improving the commercialisation of the region’s leading energy research. That said, this is not just a technology for the Midlands, or even just the UK. It provides global commercial opportunities for battery manufacturers, companies that specialise in battery protection, bus companies making a transition from fossil fuels and cities that wish to meet carbon emissions targets.

The work of the Energy Research Accelerator (ERA), a cross-disciplinary energy innovation hub which brings together capital assets, data and intellectual leadership to foster collaboration between academia and business to accelerate the development of solutions to the global energy challenge, is also looking at how best to use batteries when they are no longer in optimum condition for vehicle drives. From analysis conducted by the EIC, it has been estimated that there is 80% of a battery’s life left when it is removed from a vehicle. Funded through capital investment from the ERA, Warwick and other ERA partner universities are currently researching static second life battery use as complementary energy storage medium. In addition, new battery chemistries, materials and low-cost manufacturing methods are all part of an ongoing research programme.

Work specifically conducted by the EIC with Wrightbus will help to ensure that the new generation of diesel-electric buses meet their intended design life and continue to provide robust and reliable public transport for many years to come.

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Annex H: Detailed market priority templates

H.1 This annex provides more detailed profiles of the four Market driven Priorities.

 Future Food Processing

 Medical Technologies and Pharmaceuticals

 Next Generation Transport

 Energy and Low Carbon

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Future Food Processing

Topic Detail

Overview

Summary description of The Midlands Engine (ME) area contains both much of the most productive agriculture in Europe as well as the UK’s largest concentration of food processors and supply chain the market-driven companies. However, it is in food processing that the region is truly distinctive, with a depth and breadth of industrial scale, innovation assets and innovative and progressive priority companies unmatched elsewhere in the UK. Further growth within our food processing sector relies on continued investment in three main areas, all of which can be summarised as being focused on facilitating ‘Future Food Processing’: food processing efficiency; delivering a zero waste food chain; and, embracing food product innovation.

Detailed description of The market driven priority under the title of ‘Future Food Processing’ includes three sub-themes: the market-driven Efficient food processing is essential for all but niche food producers. For 99% of the food chain, the marketplace is characterised by high volume low margin products, with intense priority, including UK and global competition. Production efficiency is a key determinant of profitability, growth and export market success. Food and drink companies are investing in innovative identifying the relevant production processes to drive competitiveness. This includes: industrial sub-sectors  Automation and labour efficiency, with the impact of the National Living Wage making this the number one strategic priority for many food companies and scientific research areas  Low energy food processing including reduced energy use in cooking, chilling, logistics and storage, through a desire to control costs and growing supply chain pressure to reduce their food chain carbon footprint  Water efficiency due to constraints on fresh water availability in the UK and globally. Systems which reduce water use in processing and cleaning and water capture and recycling are all growing in importance  Competitive food processing creates demand for data analytics. As the quantity of data captured, through sensors or automated processes, increases, food chain efficiency requires the adoption of innovative data analysis and interpretation models to provide managers with real time decision support metrics. UK and global food chains waste comprises approximately one third of all food produced. Reductions in waste improves economic efficiency and resource utilisation. Innovative food companies are striving to become zero waste food companies through three parallel strategies:  Optimising the yield of primary products from raw materials through technology to reduce damage (e.g. improved post-harvest storage) or increase yield (e.g. more efficient cleaning of meat from carcases)  Increasing the exploitation of secondary products e.g. high protein animal feed from oilseed residues  Developing ‘waste’ product utilisation strategies for residual biomass to produce valuable products. This includes packaging waste recyclability and reuse. Food product innovation is a key strength of the UK food chain, with more new product launches (10,000 per annum) than any other country except the USA. Innovation in food is targeted at a number of key areas including:  Food reformulation to reduce levels of salt, fat and/or sugar, to address healthy eating concerns  Convenience and ease of use for the consumer as busy lives lead to a reduced propensity to cook or prepare food from scratch and increased demand for snacking and grazing  Smart packaging which enhances the product’s attractiveness, whilst reducing food waste. This is closely linked to shelf life extension which both increases consumer convenience and reduces waste. Smart packaging can also play an important role in improving food security, authenticity and traceability. Industrial sub-sectors – the food and drink industry across the ME is strong in many sub-sectors with different areas having different specialisms e.g. the Humber area is the centre of UK’s fish processing industry, Spalding is the centre of the fresh produce sector, and Northamptonshire has a concentration of cereal processors and millers. Across the ME area, many different scientific research areas are covered, but what unites the majority of these is a focus on food processing and large scale manufacturing and related supply chain development.

Key elements of the The food industry in the Midlands has both scale and breadth, with an LQ of 1.4 overall and 3.0 in the Greater Lincolnshire LEP area; 2.1 in the Marches; 1.9 in Northamptonshire LEP Midlands Engine ‘offer’ area; 1.7 in the Leicester and Leicestershire LEP area; 1.5 in the Worcestershire LEP area; and 1.4 in the South East Midlands LEP area. The food industry is thus over-represented i.e. in what ways the relative to the rest of the UK across much of the ME area. The beverage sector shows even greater concentration in local areas with it having an LQ of 3.2 in Coventry and region is differentiated, Warwickshire; 4.3 in Greater Lincolnshire; 7.3 in the Marches; and 1.6 in Warwickshire. specialised or The area is also home to many of the UK’s leading companies involved in the manufacture of agricultural (and forestry) equipment, with an LQ of 1.4 overall in the ME area and distinctive in the notable concentrations in: Coventry and Warwickshire 3.2; 4.3 in Greater Lincolnshire; and 7.3 in The Marches. In seed processing, Greater Lincolnshire records an LQ of 38.2 and market-driven priority 14.3 in the manufacture of fertilisers. Key distinctive features of the sector include:  The strength of the sector from farm to fork in every major food category, something which is unique in the UK. The location of the ME at the heart of England and UK also makes it strategically important for distribution in the food chain. Given that the food chain is the largest manufacturing sector and largest logistics sector in the UK economy, this scale means that the sector is the largest employer and contributor to GVA.

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Topic Detail

 An unrivalled concentration of global, blue chip and sector leading food chain companies including: 2 Sisters Food Group; AB Inbev UK Ltd; ABP; ACST Logistics (Carmellia Plc); Addo Group; Alpro; Arla Foods; Azelis; Bakkavor; Bedfordia Group; Bokomo Foods; Branston; British Sugar; British Pepper and Spice; Cargill Meats; Carlsberg UK; Charles Wells; Cherry Valley; Coca Cola; Country Style Foods; Daniels Group; European Oat Millers; Fastnet Fish Ltd; Freshtime Prepared Vegetables; Dalehead Foods; Danone; Emmett UK; Euro Fresh; Fresca Group; Fresh Direct Limited; Freshlinc; Freiberger UK Ltd; Frontier Agriculture; Fosters; Fowler Welch; Gist; Gleadell Agriculture Ltd; Greencore; Hain Daniels; Heygates; HJ Heinz; Hook Norton Brewery; Hovis; Icelandic Group UK; Jacobs; Jordans and Ryvita; JDM Food Group; Kerry Group Plc; Kraft; Leavesley Group (including Midland Pig Producers); Mars; McCain Foods (GB) Ltd; McCormicks; Mondelez International; Morrisons; Moy Park; Nestle; Noble Foods Ltd; Norbert Dentressangle; Openfield; Paragon Print and Packaging; Parripak Foods Limited; Pork Farms; Premier Foods; Prima Fruit; Princes; Produce World; Pukka Pies; QV Foods; Rank Hovis; Samworth Group; Smurfitt Kappa; Solway Foods; Staples Vegetables; Tayto Group; Thorntons; Total Produce Plc; TMI Foods; Unilever; Univeg; Vion; Walkers (Pepsico); Walsh Mushrooms, Warburtons; Warner Edwards; Weetabix; Wells and Youngs Brewing; Whitbread; Whitworth Brothers; Whitworths Limited; Yearsley Group; York House Foods; Youngs Seafood Ltd.  The ME region also has Regional Distribution Centres for Tesco (Lichfield and within five miles of the ME area at Doncaster), Sainsbury (Tamworth), Asda (Lutterworth and within five miles of the ME area at Doncaster), Morrisons (Northamptonshire) and John Lewis, Coca Cola and AG Barr in the SEMLEP area. In addition, the area hosts major supply chain companies serving the food service sector e.g.:  Bidvest (3663) at Nottingham and Birmingham  Booker Group with both a distribution and wholesale network for food service with over 25 locations across the Midlands  NFT in Northamptonshire.  A healthy SME economy in the food sector including fast growing companies such as JDM Foods (Bicker, Lincolnshire), Belvoir Fruit Farms (Leicestershire) and Food Fresh Technologies (SEMLEP) as well as numerous regional food groups and brands such as Select Lincolnshire and Melton Mowbray - the Rural Capital of Food. The home of pork pies and the largest producer of stilton cheese are in the region at Melton Mowbray and Long Clawson Dairy respectively. Many of the smaller food producers are innovative, growing fast and will in some cases either be purchased by larger food companies or become the larger food companies of the future.  Ancillary companies and technology suppliers to the food industry (farm to fork) also have a strong presence in the region covering numerous sectors from processing and packaging machinery, water and energy, food waste reprocessing, packaging, cooking and chilling plant, logistics, enterprise management software and QA and food testing services. Many of these companies are innovative and their success depends on developing new solutions which they can sell into the larger companies in the food chain. Key innovative companies include:  Foodtech: Apollo Engineering Technology Ltd; Coveris; Diana Foods; Euroflow Engineering; Eurofins Agriscience Services; Festo; Food Freshness Technologies (It’sFresh! Ltd); T Freemantle Ltd; Gainsborough Engineering Company; Grundwald UK Ltd; Holmach Ltd; Olmec UK Ltd; Miedema Mercer Machinery; Newtec Odense (UK) Ltd; NPD Direct; OAL; Paragon Print and Packaging; Park Acre; AMP Rose; Tong Engineering; Trepko (UK) Ltd; UK Blueprint Automation Ltd  Agritech: ADAS; Agco; Alpego UK Ltd; Basis Registration; Boston Seeds; Chafer Machinery; Dale Drills; Dupont Pioneer; Elsoms Seeds Ltd; Farmplan Computer Systems; Fullwood; Garford Engineering; Gate Keeper; Gregoire Besson UK; Grimme UK; Horsch UK; Househam Sprayers; JCB agricultural division; Limagrain UK; McConnell; Muddy Boots Software; Nickerson; Omex Agriculture; SESvanderHave; Vaderstad; Welvent Ltd; Yara UK. This strength in the commercial food chain is complemented by a depth and breadth of innovation, science and technology support assets allied to the food chain across the ME area. These innovation assets, which include a network of University departments, innovation centres and companies which support innovation are detailed in the clusters, networks and linkages and the assets sections below.

Clusters, networks and linkages

Where in the Midlands Business clusters in the sector are present in: Engine there are  Humberside around Grimsby, which is home to over 60 fish processing related companies which process 70% of UK fish. These companies range from international companies particular with thousands of staff (Youngs Seafood, Icelandic Group) through larger companies such as Morrisons to SMEs in the fish supply chain concentrations or clusters of businesses  South Lincolnshire (mainly centred on the districts of Boston and South Holland) is the UK fresh produce capital with over 1,000 lorry loads of food leaving Spalding each day to in the market-driven serve UK and international food markets. As well as the UK’s largest fresh produce sector, this cluster also includes meat processing, ready meals and food to eat on the move. priority It is also home to some of the largest dedicated food logistics companies such as Freshlinc and Fowler Welch  A second smaller concentration of fresh produce is centred on the Vale of Evesham in Worcestershire, which is also home to a proposed Food Enterprise Zone (see below)  With major cities with high immigrant populations, such as Birmingham and Leicester, the ME area also has a diverse food culture, which has led to the development of a thriving ethnic food sector, including recognition in the media under terms such as ‘Birmingham’s Balti Triangle’ and Leicester as the ‘Curry Capital of Britain’ in 2007  Cereal products in both Northamptonshire and Lincolnshire. In Northamptonshire, both major grain facilities to serve the sector (e.g. a new Camgrain facility at Newton, Northamptonshire which was developed specifically to be at the centre of where 1.2million tonnes of quality wheat is processed into food products each year) and major end users such as mills and cereal users such as Weetabix. Lincolnshire is the headquarters for both Frontier Agriculture which markets 4.5million tonnes of grain per annum and Openfield (a farmer owner co-operative) which markets a further 4.5million tonnes (in total these two traders account for nearly 40% of the UK cereal crop)  The pig and poultry sector is strong across with major companies with UK and global headquarters and major plants in the region including:

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Topic Detail

 Cherry Valley (the world’s largest duck breeder based in Lincolnshire)  Nobel Foods which specialises in eggs (Lincolnshire, Derbyshire, Nottinghamshire, Gloucestershire)  Moy Park (part of JBS the World’s 2nd largest meat company and with bases in both Lincolnshire and Derbyshire) and 2 Sisters (Headquarters in Birmingham with plants at Scunthorpe and Derby), which together are the largest two meat chicken producers in the UK  Dalehead one of the UK’s largest pig meat business has a dedicated abattoir in Spalding developed in conjunction with East Midland Pig Producers and Midland Pig Producers (part of the Leavesley Group) in Derbyshire  The Marches LEP area has a concentration of dairy processors including three of the largest companies in the UK dairy sector: Arla; Muller Wiseman Dairy; Dairy Crest, as well as many smaller companies in this sector based on the strong dairy sector in the region  The Melton area of Leicestershire has food sector employment 10x the national averages as a share of its workforce as does South Holland in Lincolnshire and Grimsby in North East Lincolnshire. Food sector Innovation Centres in the ME area include:  Six out of 17 Food Enterprise Zone (FEZ) designations across England are in the ME area: Europarc 4 (Greater Lincolnshire LEP - GLLEP); Central Lincolnshire (GLLEP); Holbeach (GLLEP), Melton Mowbray (Leicester and Leicestershire LEP) (Borough wide), Vale of Evesham (Worcestershire LEP), Central Bedfordshire – Ivel Valley Stratton Business Park (South East Midlands)  Humber Seafood Institute and Innovation Centre and the Grimsby Seafood Village which provides start up units for 20 food chain companies  Unilever at Colworth Park in Bedfordshire is a major global investor in food development and innovation. At Colworth Park they host a small cluster of companies involved in the pharmaceutical and general business sectors with a few tenants dedicated to the food chain such as Kerry Group  Southglade Food Park – Nottingham was opened in 2005 to host start up and growing food companies and has recently expanded enabling it to host up to 190 employees in multiple small food companies  Leicester Food Park provides food manufacturing space with purpose-built units, enabling new and innovative food businesses to start up and grow as well as providing established food businesses to expand Further national facilities for the industry are found at the Royal Agricultural Society for England (RASE) Headquarters at Stoneleigh Park, Warwickshire which hosts the headquarters of a large number of national bodies including:  NFU national headquarters team which is the largest membership organisation for farming in the UK  Agricultural and Horticultural Development Board (AHDB) which uses over £60m per annum of funding raised through industry levies to fund innovation, research and marketing programmes for the farming and food sectors The ME region also hosts Catapult Centres which can assist with growth of the food chain including: the Manufacturing Technology Centre (MTC), part of the High Value Manufacturing Catapult which is based at Ansty and which has relevant technology which could be applied to the industry; the Transport Systems catapult in Milton Keynes works in a sector which is very relevant to the food chain given than 28% of road freight by weight relates to the food chain.

Evidence of The food chain contains many dedicated supply chain relationships between farmers and food processors, marketers, retailers and food service companies. Most of these interactions interactions between are long standing and based upon a wide variety of business models, but the sector also sees constant evolution of these relationships. In many parts of the food sector, formal businesses in the partnerships would now account for 80% or more of total business (e.g. milk, pork and poultry production and the fresh produce sector) and in other sectors supply chain collaboration Midlands Engine in the is growing quickly (e.g. grain and cereals). market-driven priority These supply chain collaborations allow food processors and retailers to have dedicated and traceable supplies and offer farmers a more secure marketplace. In many cases these supply chain relationships now include collaboration in relation to innovation, skills and business development. The flow of innovation in these supply chains is also multi-directional and in many instances innovation is driven by smaller companies or farmers rather than the larger food processors or retailers. Other examples include food processors who have dedicated logistics providers who in some cases even have a base at food company premises. Good examples of this collaboration are found in the fresh produce sector at companies such as QV Foods and Produce World who work closely with their supplying farmers to ensure that the latest technology is employed to improve efficiency and deliver improved product quality. In the poultry sector, major processors such as Moy Park, supply the young birds, technical support and a guaranteed market to their network of contract broiler farmers. In the dairy sector, the supermarkets (e.g. Tesco and Waitrose) have been developing dedicated supplier networks who are not only guaranteed a market but who also receive training and support to develop their production efficiency. The food sector also contains hundreds of associations and groups who represent either whole sectors of the industry or particular interests e.g. the Processing and Packaging Machinery Manufacturers Association (PPMA), with many of these operating on a national basis. There are also good examples of more local and regional groups representing the sector including:  Seafood Grimsby and Humber which works to support the development of all the businesses involved in the seafood sector on the Humber  Greater Lincolnshire Food Board which is a dedicated sub group of the Greater Lincolnshire LEP focused on representing the interests of medium and larger companies in the food chain to help the LEP ensure that these companies can expand and support their supply base

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Topic Detail

 The Food and Drink Forum Limited was formed in the East Midlands in 1998 and is active in collating industry views, lobbying on behalf of the industry and delivering projects with partners (including Southglade Food Park and the Food and Drink iNet which supports innovation with experts drawn from Nottingham Trent University, the University of Lincoln and the University of Nottingham).

Evidence of Key examples of interaction between businesses and the research base include the largest concentration of Innovate UK SAFIP (The Sustainable Agriculture and Food Innovation interactions between Platform) projects with over £20m of funding awarded by this programme to projects based in the region for projects with a total value of £35m – 24% of the total number of UK businesses and the projects and 21% of the funding - the largest of any region in the UK. In relation to Research Council funding, between 2010-2015, the region accounted for 33% of the funding for research base in the food science and nutrition projects (6 projects); 40% of agri-environmental science (38 projects); and 34% of plant and crop science funding (22 project) awarded across the UK. Midlands Engine in the Example projects include: market-driven priority  Efficient Food Processing:  Advanced Mixing and Cooking Technologies (AMACT) - OAL Group  Advanced Cooking and Cooling Technology (ACCT) - LINDE Group and Iceland  Novel computer vision techniques for food quality analysis - Ishida UK  Distributed UV and Near Infra-Red and Fluorescence sensing system for real time monitoring of food quality and contamination and process control - Arden Photonics  Control of waste:  Food Waste Reduction using Volatile Biomarker Monitoring. Monaghan Mushrooms  Detection of contamination on lamb carcasses: reducing waste, improving efficiency and meat safety (C-DeS) - Tulip Ltd  EnviroSave - Environmentally Cost Saving Efficient and Hygienic Humidity and Temperature Control System for Safe Storage of Meat and Poultry Products - P.A.K. Engineering Ltd  Reducing waste and improving quality in the food supply chain using cold plasma technology - Kanes Foods Ltd  Food Product Innovation:  Food Industry Laser Mediated Sealing’’ (FILMS) - Marks and Spencer plc  Reduction of Fats, Salts and Sugars and the Increase of Fibre in Premium Snacking Products - Kettle Foods  Pumpkin derived compounds to treat Type 2 diabetes - Enimate Ltd  Reduction of sugars and fats by creation of adhesive structures at lower sucrose concentrations. Biopolymer Solutions Ltd AHDB, based in Warwickshire, has also been investing in many projects which relate to the food chain with the aim of adding value or improving supply chain performance. In recent years this has included a major focus on developing and then implementing environmental roadmaps for the industries it serves including targeting reductions in the carbon and water footprints in the food supply chain.

Evidence of linkages Key examples of linkages between organisation in the region and key organisations outside the region include: between organisations  Pepsico is coming to the end of a five-year challenge to its farmer supply base to reduce its water and carbon footprints by 50% in 5 years: the 50 in 5 programme. This within the region and programme includes potatoes supplied to its ME region processing plants but some of the farmer supply base and some research expertise are drawn from outside the area key organisations (e.g. University of Aberdeen which specialises in food chain carbon foot-printing assessments). outside the region in the market-driven  Many medium and large regional food chain companies are part of larger global groups and work with their parent company, group on both commercial development and priority innovation. Examples include specialist food ingredient company Diana Foods based adjacent to NCFM at Holbeach which is part of a global group, Moy Park one of the region’s largest food companies which is owned by JBS in Brazil, Bakkavor which has its largest plants in Lincolnshire but which is an international company and many others.  The majority of food companies serve a national or international market as part of supermarket or food service supply chains. These supply chains drive innovation. Many larger regional businesses are also part of national innovation programmes run by the Food and Drink Federation which have been targeting reductions: CO2 emissions; Food Waste; Packaging; Water; Transport, through its Five Fold Ambition programme and earlier projects such as the Federation House Commitment.  The region’s Universities and research centres working on food related projects have completed hundreds of research collaborations with partners (both industry and research) outside the region, in other parts of the UK and across the World, including projects supported by Innovate UK, the Research Councils, Horizon 2020 (and Framework Programmes) etc.

Assets

The key research  National Centre for Food Manufacturing (NCFM), which is the largest provider of food chain HE courses in the UK and Lincolnshire Institute for AgriFood Technology (LIAT) at centres, university the University of Lincoln which is a major provider of Innovate UK funded applied research projects in the food chain departments, RTOs,  Sutton Bridge Crop Storage Research (AHDB Potatoes) is a top 5 global root vegetable storage research centre based in South Lincolnshire major private sector R&D facilities, NHS etc.

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Topic Detail that support the  FRPERC, the Food Refrigeration and Process Engineering Research Centre (FRPERC) at The Grimsby Institute has been in existence for nearly 50 years and specialises in formation and growth of applied research with industry on how to refrigerate and process food products businesses in the  EPSRC Centre for Innovative Manufacturing in Food is an integrated centre hosted by the Universities of Nottingham, Birmingham and Loughborough. The centre conducts market-driven priority in industry backed applied and fundamental research in novel food manufacturing techniques and is part of the larger national EPSRC Centres of Innovation network the Midlands Engine  Warwick Crop Centre is an internationally recognised centre for strategic and applied research in sustainable agriculture, horticulture and food security and part of the Warwick School of Life Sciences which was ranked 2nd in the UK for Agriculture, Food and Veterinary research in the Government's 2014 REF assessment  Sutton Bonnington which is home to both the University of Nottingham’s School of Biosciences (which includes a food science unit) and the University's new School of Veterinary Medicine and Science. The Food Science work includes a Food and Biofuel Innovation Centre  Harper Adams University which as well as work on the food industry is the largest national provider of agricultural higher education. Harper is also a partner in one of the Centres for Agricultural Innovation, Agricultural Engineering Precision Innovation Centre, (Agri EPI), which also includes ME based Cranfield University and Agco in its core team  University of Northampton has a team which specialises in food waste streams and how they can be exploited to produce new products  Cranfield University has particular relevant strengths in agriculture, food science and nutrition, water and soils engineering. Focused on postgraduate education, training and research Cranfield also has extensive global connections and strong international student base  Unilever at Colworth Park in Bedfordshire is a major global investor in food development and innovation and the Colworth site hosts its global R&D centre for ice cream and beverages. This facility also hosts an office of the Institute of Manufacturing from Cambridge University

Investment

The most significant The ME region accounted for 39% of UK patents in food chemistry over the period 2004-2013, with 186 patents in total. investments by the Key investments by the private sector include: private sector in innovation and R&D  Park Acre are investing heavily in innovation in nutraceuticals to serve food chain customers across Europe. The company has a full time research team whose director is also a activity in the Midlands visiting lecturer at the University of Lincoln and on the Greater Lincolnshire Science and Innovation Council to ensure that the company exploits local expertise to fuel its innovation programme and growth. Engine in the market- driven priority  Just Egg in Leicestershire are a dedicated egg processing company which has won innovation awards for projects such as turning 30 tonnes per month of ‘waste’ egg shell into sustainable packaging  Peterborough based OAL technologies has installed a trial robotic testing rig at the NCFM in Holbeach to trial how to bring automotive and other robotic technologies into the food sector. This is testing how to handle liquids, cooking processes and hygiene issues in a food factory environment using industry standard robotics to reduce costs. OAL is committed to bringing about these advances though programs of holistic innovation across four connected themes: eliminate waste; improve product quality; ensure food safety and traceability; offer flexibility. Since 2012 it has accelerated its investment in R&D to in excess of 8.2% of turnover to innovate food production systems and technologies.  Garford Engineering (Deeping St James, Lincolnshire) have developed robotic weeding and row crop technologies which deploy state of the art plant recognition vision and software systems to automate crop work and promote precision farming. These are now being exported across the World and enable weed control to be automated and compatible with organic standards.

The most significant The most significant inward investments into the ME region in the food sector include: inward investments into  Morrisons Seafood was set up in 2012 to provide dedicated fish processing to supply their stores. The initial investment at Europarc, North East Lincolnshire created over 200 the region in the jobs and in 2015 the business began development of phase 2, also on Europarc, which employs an additional 250 people. Midlands Engine in the market-driven priority  Camgrain has made an investment in a new grain storage and advanced processing centre in Northamptonshire (NN14 1FL) to enable it to supply vendor assured grain to the food industry in the ME region. This follows similar investments in Cambridgeshire in 2008-9 and is part of rationalisation of the supply chain to reduce waste etc.

 UK Steel Enterprise is one of the country’s longest-standing business-support organisations and has made two investments of £500k into Lincolnshire-based Abbeydale Food Group. This enabled Abbeydale Food Group to more than double its turnover to over £10m (2013) and workforce to over 150 people. It specialises in the supply of prepared foods, including traditional pies and a range of potato and vegetable dishes for supermarkets, foodservice and other food manufacturers.  JDM Food Group moved into Lincolnshire as a £4m turnover company, having been set up in Cambridgeshire. It has expanded significantly every year in the last 5 years through investing on its dedicated 12 acres site and now employs over 250 staff and has a turnover of over £40m. It is innovation led and focuses on UK and international markets as a specialist supplier of ingredients to other food manufacturers. It has been rated as the second fastest growing privately owned company in the UK food sector.  Karro Food Group in Scunthorpe announced plans in January 2016 to create an additional 140 jobs to add to its existing 200 strong work-force to increase its capacity to supply bacon products in the UK.  Arla’s made a 2014 investment in Aylesbury in a new £150m dairy (one of the largest in Europe). This site aims to be the World’s first carbon neutral dairy plant. The development created 680 jobs.  Alpro, Carlsberg UK, Plant Lipids, Zwanenberg, TMI Foods have all invested in Northamptonshire in recent years.

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Market developments

How the market-driven The market driven priorities of the food chain have continued to evolve rapidly over the last five years. priority in the Midlands Major changes have been seen in the priorities of the market post-recession, with consumers changing the way they consume food and placing a different emphasis on the factors Engine has evolved which drive their purchasing decisions. However, for most food producers their customer is the supermarkets or major food service companies, who filter these consumer drivers and over the past five also add their own interests into the demands placed on food suppliers. Key areas of change in the food market are: years.  Food safety, authenticity and traceability – consumers are concerned about whether they can trust that food is what is claimed to be, is authentic and traceable back to its source. Food scares, notably Horsegate, has led to new legislation, food traceability systems and the development of tests to show where products were produced.  Focus on food costs – pre recession, discounters had a small share of the grocery market, upmarket retailers did not stock value ranges and most consumers only shopped in one main food store. The market is now much more fragmented, with many consumers purchasing both value products and luxury premium food products, using more than one retailer and being overall far more focused on product price. The result is a focus on driving down costs right along the food chain by taking out costs. This challenge has been much harder to achieve with the introduction of the National Living Wage (NLW) and this is already leading to an increase focus on automation to reduce labour costs so that cost price pressures can be addressed.  Health and diet – for a significant proportion of the population the perceived health benefits or dis-benefits of particular foods is now a major factor in their purchase decisions. The focus was on salt and fat, where good progress has been made, political and consumer campaigns have now placed more emphasis on sugar. There remains, however, a lot of consumer ambivalence to the messages on dietary health and scepticism born out of a perceived lack of clarity from the scientific community about a ‘healthy diet’.  Food waste – pre recession in 2007 food waste was seen as a low priority by most consumers. Recession, rapid increases in food prices during 2008-12 and public awareness campaigns (e.g. Hugh’s war on waste) have changed this and reducing food waste is now seen as a good way to moderate food spend as well as moral and public good imperative.  Energy, water and carbon – whilst energy and carbon have been important market drivers for at least the last five years, some significant food chain companies and retailers have also now begun to target water efficiency. This is driven by long term challenges on fresh water supplies globally and a desire to be ahead of regulation or costs rises which this may result in.

The future prospects In the medium to long term, the food sector can be expected to increase its focus in three main market-driven priority areas which respond both to consumer pressures and areas in for growth in the which rapid technological development and scientific breakthroughs are enabling innovation. These three areas are: market-driven priority, Demand for automation and labour efficiency in the food chain – the food industry remains a large employer with over 1.2million employed directly in food processing, including taking into account 422,000 employed in food manufacturing, 225,000 in food marketing and wholesale and 476,000 on farms, and this rises to 3.8million when food retail and catering are added to the wider market and total. With many low paid staff along the food chain, but concentrated in food retail and catering the National Living Wage (NLW) will have a major inflationary impact on the sector’s technology changes. costs through to at least 2020, whilst consumer pressure is seeking to keep food prices down. These costs rises are also unique to UK producers as international competitors are not seeing the same rise in costs and in most countries the minimum wage is well below the levels which will apply in the UK by 2020. The sector has to increase its labour productivity very quickly as a result and this will mean a wave of automation across the food chain. Whilst some automation solutions exist, in many areas additional innovation is needed to create the new systems and machines needed to respond to this challenge including: robotics; sensors and control systems; data analytics, computer learning and vision systems, to enable automation to increase labour productivity. Food waste reduction and efficient resource utilisation – the food sector is a major user of resources (for example 75% of global fresh water abstractions and 17% of final energy consumption in the UK). The sector will remain very focused on making its production more efficient both because being seen to be efficient is in increasing demand amongst customers and consumers, but also because it makes good business sense in a sector where margins are relatively small and resource costs are a high proportion of total costs. The concept of zero waste, which has been embraced by some food companies with a Midlands Engine base e.g. British Sugar, is now being taken up more widely. The Food and Drink Federation which represents larger food processors has been running programmes targeted at carbon footprints and water efficiency. Companies can be expected to want to continue to push to reduce waste, find innovative solutions to make additional products from ‘waste’ co and by product streams and to look for ways to increase the yield of primary products. New food products, authenticity, provenance and traceability – consumers are likely to become even more demanding in the expectations they have for the food products they consume. With a desire to experiment with new foods, a desire to know more about how food was produced, who produced it and the impact it has on them, the market is expected to see growing consumer pressure to create healthier foods (low fat, salt and sugar), which are traceable and authentic. Furthermore, evidence shows that the demand for convenience is continuing to grow and is now extending even into ‘foodie’ culture, where these food enthusiasts are, despite their interest in provenance and natural or authentic foods, also wanting convenience to enable them to consume the premium foods they desire but without the time normally required to search out and prepare these foods. These trends are not unique to the UK, and growing wealth globally is set to have trebled the number of middle class households between 2000 and 2030, meaning that by 2030 over 2billion households globally will be able to make real choices in the foods they choose to purchase. This will increase the demand for convenience, added value foods, eating on the go and food service.

External perspectives

Key competitor regions East of England – this region has the largest concentration of food science R&D in the UK (arguably in Europe). The East of England’s food sector R&D is World class and very in the UK focused on academic rather than industry impact. Major new investments are being made, notably the forthcoming £81m investment at the Quadram Institute at Norwich Research Park to create a new national centre for dietary health research. East of England agriculture is the most profitable in the UK and similar strengths in its product mix to the ME area except dairy. The East of England has fewer global food companies and a less well developed added value food sector – on balance it is a net ‘exporter’ of agricultural production

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which has value added elsewhere (some in the ME area given the concentration of food processing in the ME area). The East of England benefits from easy access to the large food markets in London and the South East of England as well to Europe’s golden triangle via the East coast ports and M25/Dover. Scotland – the food sector is a major priority for the Scottish government and this has led to major investment in R&D and skills provision. Scotland is a major recipient of agri-food R&D spending by RCUK and Innovate UK with a particular focus on livestock production, disease and sustainability research. It has the UK’s largest agri-food centre, the result of mergers encouraged by the government. The resultant centre, SRUC, makes co-ordination much better than in the ME region. SRUC combines a large student population, with strong research base, innovation support and business consultancy services. The food sector in Scotland is not as diverse as in the ME area with fewer global companies. However, in some sub-sectors, such as red meat, whiskey and fish processing, it has a very strong presence and World renowned brands. Scotland does suffer to some extent from its relatively small home market and location, which means it has to focus on selling food to other regions and countries but faces substantial transport costs to do this. Northern Ireland – the food sector is a priority for the Northern Ireland administration and whilst it has a less diverse food sector than the Midlands Engine area, it has international companies and particular strengths in the dairy and meat sectors. Because of its strategic priority for economic development, the devolved administration has invested in the development of robust structures for skills and business innovation support. For example, the College of Agriculture, Food and Rural Enterprise (CAFRE) includes a dedicated food industry support division which works with over 250 food industry partners on workforce development, innovation and business development. It also hosts both a Food Technology Centre and Food Business Incubation Centre. CAFRE is part of the Northern Ireland Department of Agriculture, Environment and Rural Affairs’ Food and Farming Group and thus works very closely with other government initiatives and support.

Key competitor regions Regio Food Valley Netherlands and the wider Netherlands food industry. The Netherland has a large integrated farming and food sector which is very international in its focus. With a outside the UK focus on domestic production to meet international market demands as well as local sales, and with a major role in trading food produced by other countries, the Netherlands is a global food powerhouse which performs well above the level that its share of global population or domestic market would suggest it should. This outperformance has been built on long term political support for the industry, the mercantile heritage of the Dutch people and businesses and a commitment to creating national structures to give critical mass to research, innovation support and skills development programmes. Wageningen University Research (UR) for example is the result of a merger of many previously independent research centres, teaching establishments and consultancy services to create the largest agri-food centre in Europe with 11,000 students, 8,500 staff and a budget of over £500m per annum. Wageningen is now ranked number 1 globally in the QS rankings (2016) for Agriculture and Forestry. This has enabled Wageningen to win more FP7/H2020 projects than any other and to be ranked in the top five global centres in most of the disciplines it focuses on. The Regio Food Valley is a relatively new structure which has been created to build on this track record of success, with the specific aim of positioning a more formal partnership between the food industry (over 150 larger companies) and the Dutch business support and innovation structures so that they are the leading global centre supporting the food industry. California is a global scale producer of food, with a particular specialism in fresh produce given its climate, local demand and heritage in this sector. Whilst facing resource constraints, notably water during the prolonged recent drought has caused the industry real problems, it has also led to a real focus on innovation. The twin factors of increased challenges in sourcing labour and the presence of the technology cluster which California is famous for, have been brought together in a focus on automation, robotics and precision agriculture. The University of California, Davis is ranked 2nd and University of California, Berkeley is ranked 4th in the QS World university rankings (2016) for Agriculture and Forestry, showing how strong the state is in the academic disciplines which underpin its World class agri-food industry. The sector is now backed by very significant VC backed investments in agri food technology, often underpinned by key Silicon Valley backed expertise. The industry is making key investments in big data analytics to underpin agri food technology, robotics and automation systems, remote sensing packaging and processing technology. Rapidly emerging as one of the main centres for global food manufacturing innovation. New Zealand has well developed export orientated food sectors and abundant natural resources. This has led to large effective structures and companies which have been focused on market and technical innovation. One very interesting example is the farmer owned Fronterra co-operative, which processes and exports dairy products from 10,500 farms. It now has approaching a 30% share of global dairy exports and is very active in innovation in the food chain on behalf of its farmer shareholders. As a company it is export orientated, R&D intensive (both on food products and dairy production systems) and outward looking with strong links to the academic and research base. It has revenues of $22billion, employs 22,000 staff and sells dairy products to 100 countries. It is striking that Fronterra describes itself as a ‘global dairy nutrition company’ rather than as a farmer owned co-operative. There are also substantial investments being made in emerging economies in the agri-food sector, with two countries of particular note given the scale of their agri-food sectors, the pace of the expansion in food production they have seen and a growing focus on trade, investment in R&D and global competitiveness. For example: Brazil has a large scale agri- food sector which has also seen steady growth over recent decade, transforming the country into a global agri-food superpower. This has enabled the growth of global food businesses, e.g. JBS, the parent company of Moy Park in the Midlands Engine area, is Brazilian owned and now the 2nd largest protein company in the World with sales of over $50billion. Brazil represented 4% of total global R&D spending in the agri-food sector in 2008 (ASTI 2012). China has been investing heavily in the agrifood sector to increase its production, respond to growing demand for protein and manufactured food products as its economy has grown, wealth increased and diets changed. This is reflected in the last global assessment of agri-food R&D conducted by ASTI (CGIAR 2012) using 2008 data which showed that between 2000-‘08, China accounted for 35% of the total global increase in R&D spending in the sector and by 2008 represented 13% of total global investment in the sector. Over the period 2000-’08 its investment rose in $ terms four times as quickly as the USA.

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Medical Technologies and Pharmaceuticals

Topic Detail

Overview

Our priority area of Medical Technologies and Pharmaceuticals primarily focuses on Medical Devices, Diagnostics and Software as a Medical Device i.e. those technologies following a Medical Device regulatory pathway and conventional pharmaceuticals. We will also embrace other aligned emerging/next generation medical technologies including those focused on regenerative medicine that are largely within the academic science base currently. Within this scope, we will have a particular focus on growing activity in diagnostics (including IVD and Diagnostic Imaging) because of its importance in medicine and the personalisation of medicine, significant linkages to our life sciences capability and pharmaceutical heritage, engineering and bio-engineering strength, national and regional recognition of diagnostics as a next step for devices businesses, and evidence of success in Summary description of translation from academic science to commercial success (including trade sales) and patient and healthcare system impact. We will also work to sustain our activities across the the market-driven Midlands Engine in pharmaceuticals. The region has great strengths in pharmaceutical research and contract pharmaceutical and clinical research organisations supported through priority industrial incubators such as BioCity and Medicity with expansion potential at Charnwood Campus which has attracted Almac to the UK. There will be a particular focus on closing a regional innovation gap by improving routes to market working with ‘early adopters’, including piloting approaches with Defence Medicine because of its unique innovation system position, concentration in the Midlands Engine and links with distinctive regional capabilities in Trauma Medicine. The priority will also leverage key regional assets including our large and stable multi-ethnic population, our five large NHS trusts and their large integrated hospitals, our academic life sciences capabilities, pharmaceutical and manufacturing heritage, pan-regional investments in medical technologies incubation and in rehabilitation.

14% of all UK Life Science employment is in the Midlands (30,565 jobs) and the Midlands is ranked in the top three for employment in three out of four sub-sectors identified in the BIS Bioscience and Health Technology Database2. putting the Midlands Engine on a par with the East of England (15% of UK with 33,000 jobs) which is considered by many as the UK “Biotech Centre” and trailing only the South East with 22% of UK employment. The Midlands particularly excels in specialist service and supply businesses, ranking first ahead of the South East and East of England with nearly 12,000 jobs, with over 17% of the national employment total; 16% in BioPharma and nearly 20% in Med Tech. This growing sub-sector comprises a wide range of companies spanning drug discovery, contract research and manufacturing, suppliers of consumables and reagents for R&D facilities, providers of specialist analytical, IT, recruitment and logistics services as well legal and regulatory expertise. With the global changes taking place, particularly in the pharmaceutical industry, there are Detailed description of significant opportunities in drug discovery and personalised medicine and this growing specialist sub-sector will play a pivotal role. Notable high growth companies indigenous to the the market-driven Midlands include the Binding Site, Quotient Clinical, Sygnature Discovery, Charnwood Molecular, and Xenogesis. The further success of local companies can also be evidenced priority, including through the healthy level of company acquisitions and trade sales that have occurred in recent years (see investment section below). Alongside these local companies, there are identifying the relevant established multinationals including Parexel, Clinigen Group, Worldwide Clinical Trials, 3M, and Walgreens Boots Alliance and this sub-sector will be further strengthened by the industrial sub-sectors expansion of Almac from their Northern Ireland Headquarters on to the Charnwood Campus in Leicestershire. and scientific research areas The Midlands also has strength in core Med Tech industry, with 12% of employment in Medical Technology in the West Midlands with 11,000 employees which combined with the East Midlands (7%, with 6,000 employees) makes the Midlands the second largest Med Tech region by employment. This will be further strengthened with the Defence Medicine Rehabilitation Centre relocating to the region; aligning to regional research excellence in sports and exercise medicine, regenerative medicine, nutrition, trauma and surgical reconstruction. The breadth of employment across the whole sector provides the region with an exceptional opportunity to support the entire supply chain for research and development of new therapeutics and medical devices. The broad diversity of companies in the region are a magnet to attract and retain high paid, qualified staff through broader career opportunities with concomitant benefit to the regional economy. The diversity of companies also provides sustainability in the sector as it is not dependent on one principal company and prevents susceptibility to further impacts on the regional economy as observed with the loss of AstraZeneca.

Med tech innovation requires ABC (Academic, Business, Clinical) actors, consequently the priority will also leverage distinctive regional innovation assets:  Our large, ethnically diverse and stable population (multiple generations of key ethnic groups) provides an ideal ‘living laboratory’ for supporting translational medicine and, more widely, the balance of market push and pull that keeps life sciences innovation relevant and applicable.  The Midlands is a critical hub for patient care in the UK, with a population roughly 1/6 of the entire UK (>11 million), managed through over 34 NHS Trusts. Key elements of the  The Midland Engines has five (soon to be six) medical schools; each benefitting from proximity to, and close working with, hospital trusts. The training activity in medical schools Midlands Engine ‘offer’ is very large representing ~20% of the national output; this is also reflected in the scale of our regional training capacity in science and engineering. Our Medical schools are now i.e. in what ways the working together with other key stakeholders as Midlands Heath Innovation. Birmingham’s new Dental Hospital is the first integrated, stand-alone dental hospital and school to region is differentiated, be built in the UK for c.40 years. specialised or  The region has significant strength in clinical trials in terms of both infrastructure and expertise - the Institute of Translational Medicine (ITM) and the Birmingham Centre for distinctive in the Clinical Trials, with specific expertise in the design and running of medical devices trials (D3B team) and high accrual rates, Europe’s second largest academic trials market-driven priority infrastructure (only behind Oxford), together with the Leicester, Nottingham, Warwick, and Derby Clinical Trials Units, amounts to a significant proportion of the UK’s clinical trials capability. Other key related assets include Health Economics with a devices and diagnostics focus (MATCH – Birmingham, Nottingham and Warwick); and Birmingham’s Patient Reported Outcomes Centre.  The Midlands has extensive scientific and research capabilities essential to or directly involved in the development of diagnostics, medical devices, pharmaceuticals and genomics and stratification: Research expertise exists in: translational medicine, regenerative medicine, precision medicine, cancer and genomics, immune-mediated inflammatory diseases, structural biology, healthcare technologies (devices, diagnostics & biomaterials), medical imaging, cognitive neuroscience, health exercise science,

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respiratory diagnostics, and public health. Biomedical technology/engineering – applied to wellbeing through behaviour change to precision medicine – is a unique strength which represents a major potential growth area for delivering tangible impact through our collective research assets (see below under assets for details).  The Midlands has an internationally unique manufacturing and engineering heritage and culture – “we can make anything” (as is discussed elsewhere in the SIA). This has been continuously refreshed by national and regional investments in the science base by repeated and significant EPSRC investments and by Innovate UK in particular by the creation and growth of the Manufacturing Technology Centre on Ansty Park. Our commercial manufacturing and supply capability and capacity is emphasised by the sustained location of 3M, Walgreens Boots Alliance, and Thermofisher in the region and in our distinctive regional manufacturing and supply businesses in the sector including Cobra Biologics, Salts Healthcare, Kimal, and Pennine Healthcare. This gives us a distinctive regional position in translation, that of industrialisation (late stage (Cooksey II) translation).

Clusters, networks and linkages

Where in the Midlands Medical technology businesses within the region are widely distributed and largely map to conurbations (see Figure 4.2 of main report) with concentrations in Coventry, Greater Engine there are Birmingham and the Black Country, Stoke on Trent, Leicester and North Leicestershire, Greater Nottingham and Derby. particular Significantly medical technology and pharmaceuticals has been identified across the Midlands Engine as a growth area, this is reflected in mature and maturing “med-tech” and concentrations or “pharma” focussed incubator and space investments including the BioCity Group (one of the largest bioscience incubator networks in the UK with over 200 companies, that includes 2 clusters of businesses sites in Nottingham with c.1000 people), ITM, Biohub, and Battery Park Life Sciences Campus (Birmingham), Life Science Enterprise Zone (Nottingham and Derby); and emerging in the market-driven initiatives including the Medical Technology Innovation Facility (Nottingham), the Digital Health Quarter (Birmingham), Aylesbury Vale initiatives including Woodlands Enterprise Zone, priority and the plans for a Life Sciences Opportunity Zone and Enterprise Zone on the Charnwood Campus (the Loughborough site exited by AstraZeneca in 2009).

There are many networks connecting academia, industry and clinicians at a regional level including: Evidence of  two Medlinks (East Midlands and West Midlands) interactions between  two Midlands Academic Health Science Networks businesses in the Midlands Engine in the At a sub-regional level networks include: market-driven priority  Birmingham Science City, an alliance of public, private and university stakeholders working together  a life science supply chain special interest group.

There are many instances of collaborations between the businesses and the science base. Significant exemplars are: Evidence of interactions between  The Healthcare and Bioscience iNet project led by Medilink EM with 5 regional universities and 3 Hospital Trust partners, supported over 1000 regional companies, helping businesses and the launch over 25 new products and instigated over 300 collaborations with the knowledge base; research base in the  The Birmingham Phenome Centre is a collaboration between University of Birmingham and 4 companies (ThermoFisher, Bruker, Waters and Beckman Coulter)in the field of Midlands Engine in the metabolomics diagnostics; market-driven priority  The Centre of Excellence in Sustainable Chemistry, a collaboration between GSK and the University of Nottingham.

Evidence of linkages Innovate UK and NIHR data on successful grant awards in the healthcare area shows that the region has an appetite to use national R&D funding to support its innovation. The region between organisations also is a partner within the European Institute of Innovation and Technology (EIT) Health Knowledge and Innovation Community (KIC) promoting entrepreneurship and innovation in within the region and healthy living and active ageing via the WM AHSN. key organisations outside the region in the market-driven priority

The key start-ups in the  Aston EyeTech Ltd, AEL was set up in December 2013 in order to commercialise exciting new products emerging from Aston University’s Faculty of Life and Health Sciences. Midlands Engine in The Company’s products are focused on supporting primary care optometry, both on the high street and in the public health arena. recent years in the  Binding Site, Edgbaston, Birmingham. Binding site researches, develops, manufactures and distributes specialist immunodiagnostic assays & instrumentation. Binding Site market-driven priority, provides specialist diagnostic products to clinicians and laboratory professionals worldwide. Founded by researchers at the University of Birmingham, Binding Site has continued and why they are to build on its strong scientific foundations, supporting research and development within its field and responding to the changing needs of patients, researchers and clinicians for important over 25 years. Binding Site has an annual turnover of £80M and employs ~620 people.  Charnwood Molecular, Loughborough. Leicestershire. Operating from two state-of-the-art research facilities in Loughborough and BioCity, Nottingham, UK, it is a leading Contract Research Organisation providing medicinal and synthetic chemistry services to the global pharmaceutical, biotechnology and chemical industries.  Haemostatix Ltd, Nottingham, was co-founded in 2003 as a spin-out from the University of Leicester. The Company was established to commercialise a new technology platform based upon a specific peptide sequence that binds to fibrinogen - a protein essential to the formation of clots. The technology was first applied to the development of a systemic platelet substitute, but in 2010 the Company re-focused on a topical coagulant.

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 Sygnature Discovery, BioCity, Nottingham. Sygnature Discovery is the UK’s largest independent provider of integrated drug discovery resource and expertise. Its mission is to accelerate the discovery of new medicines from the laboratory into development to treat patients with a range of debilitating and fatal diseases.  Xenogesis, Biocity, Nottingham. XenoGesis Ltd. is a laboratory-based contract research organisation (CRO) specialised in preclinical drug metabolism & pharmacokinetics (DMPK), quantitative bioanalysis and expert interpretation. The core XenoGesis team has an enviable track record of delivery in drug discovery.

Assets

The key research  Within the 34 hospitals, there are 4 adult and 2 paediatric trauma centres and 7 major cancer centres. There are also strong collaborative networks between the NHS Trusts, centres, university universities and businesses, including the two Academic Health Science Networks overseeing the East and West Midlands and the associated Deaneries/Local Education & departments, RTOs, Training Boards for clinical training. major private sector  Key academic locations include: Universities hosting medical schools where medicine spans from prevention to rehabilitation – Aston, Birmingham, Keele. Leicester, Nottingham R&D facilities, NHS etc. and Warwick; Life Sciences at scale – Birmingham, Leicester and Nottingham; Schools of Pharmacy – Aston, Birmingham and Nottingham, Schools of Ophthalmology – Aston; that support the Engineering and Bio-Engineering – Birmingham, Loughborough, Nottingham and Warwick; Warwick – Digital Health. formation and growth of businesses in the  Our research strengths are supported by many HEI, public sector and industry-based disciplines (medical, nursing and health professionals, life sciences, engineering and market-driven priority in business schools). the Midlands Engine  Key research assets include: six Biomedical Research Units (BRU) (Hearing, Digestive Diseases, Cardiovascular, Respiratory, Diet Lifestyle and Physical Activity, Liver Disease) funded by National Institute for Health Research; six Arthritis Research UK Centres (Tissue Engineering; Musculoskeletal Ageing; Pathogenesis of Rheumatoid Arthritis; Experimental Arthritis Treatment; Pain; Sport, Exercise & Osteoarthritis); 2 UK Research Council CDTs; National Centre for Sports Exercise Medicine (NCSEM). Other leading centres include: UK’s largest NIHR/Wellcome Clinical Research Facility; the national centre for Trauma Research, Healing Foundation Burns Centre, Bloodwise Trials Acceleration Programme, NIHR/MOD Surgical, Reconstruction and Microbiology Research Centre, NIHR Health Technology Cooperative, Royal Centre for Defence Medicine, Birmingham Centre for Computational Neuroscience and the Aston Brain Centre.West Midlands Genomic Medicines Centre. Leicester 1000,000 Genome Project lead for circulating DNA, Birmingham ITM’s Single Cell Genomics lab, Birmingham Clinical Immunology Service, ITM’s Immunophenotyping Facility, Birmingham Phenome Centre and Biomolecular NMR Facility, Birmingham Centre for Computational Biology, Leicester Alan Turing Institute, Warwick Institute of Digital Health, Birmingham Health Technologies Research Institute, Sir Peter Mansfield Imaging Centre Nottingham; Birmingham Human BioRepository (HBRC), East Midlands Pathology Service, Nottingham Centre for Healthcare Equipment and Technology Adoption (CHEATA), Nottingham Anthony Nolan Trust Research Centre, Leicester Centre for Medicine, The joint Universities of Birmingham and Nottingham Centre of Membrane Proteins and Receptors (COMPARE), Loughborough Centre for Biological Engineering.

Investment

The most significant  There have been a significant number of acquisitions made in the region building on its growing track record of generating successful stable and growing start-ups in medical investments by the technology, pharmaceuticals and services exploiting academic intellectual property and intellectual assets arising from experience in large pharmaceutical businesses. This private sector in represents a significant change in regional performance over recent years. Examples include: Quotient Clinical acquired by Bridgepoint Development Capital in 2013 (sum innovation and R&D undisclosed), Molecular Profiles acquired 2014 (total consideration of approximately $25.0 million comprising $16.7 million in cash and 1,051,323 shares of Columbia common activity in the Midlands stock, representing ten to eleven times Molecular Profiles’ projected EBITDA for its fiscal year ending July 31,2014), Haemostatix acquired by ErgoMed (£8m upfront + £20m Engine in the market- add-ons), Source BioScience acquired by Continental Investment Partners SA and Harwood Capital LLP, through their bid vehicle Sherwood Holdings Ltd for £62.9m in July driven priority 2016. Abingdon Health (HQ’ed in York) in 2014 acquired two spin-outs from the University of Birmingham: Serascience, a specialist cancer diagnostic company, and Linear Diagnostics Ltd (LDL) developers of a suite of rapid, hand-held diagnostic tests. PhosImmune, co-founded by a University of Birmingham academic, has just been acquired by Agenus for $44M ($9.9M cash with an addition $35M in milestone payments. Aesica, a leading pharmaceutical contract development and manufacturing organisation (CDMO) was acquired by Consort Medical in 2015. Perhaps most significantly, the Burton on Trent based Clinigen Group have recently acquired Link Healthcare Pty and Biocodex. and Oncimmune, based on University of Nottingham intellectual property, floated on AIM in May 2016 with a market capitalisation of £66M.  The £300M Defence and National Rehabilitation Centre is currently under construction at Stanford Hall, Nottinghamshire. This will relocate military rehabilitation from Headley Court, near Epsom. The investment has been brought together by the Black Stork Charity at the instigation of the late Duke of Westminster. This significant investment is important in its own right, but has the additional significance of confirming the concentration of Defence Medicine in the Midlands Engine with headquarters at Lichfield (Whittington), significant investments at the Queen Elizabeth Hospital Birmingham, the Royal Centre for Defence Medicine Birmingham and the National Joint NIHR/MOD funded Surgical Reconstruction and Microbiology Research Centre Birmingham. This significant defence medicine capability is complemented by regional strengths in trauma medicine, our region includes Stoke Mandeville, the Nottingham Trauma Centre and our distinctive trauma capabilities reach into Wales from Stoke-on-Trent and Oswestry hospitals.

The most significant Almac are making a significant investment (£16m) in the area by locating on the Charnwood Campus and creating 160 jobs initially. They are an anchor tenant for the Campus and, inward investments into because skills present in the region formed a key part of their location decision, this reinforces the importance of specialist life science skills retention in the region. The Almac Group the region in the is an established contract development and manufacturing organisation that provides an extensive range of integrated services globally to companies within the pharmaceutical and Midlands Engine in the biotech sectors. The services range from R&D, biomarker discovery and development, API manufacture, formulation development, clinical trial supply, IXRS technology(IVRS/IXRS) market-driven priority through to commercial-scale manufacture and companion diagnostic development. Also the IT company Apical (now owned by ARM) are also in the process of establishing on the site with an additional 80 employees, growing to 120 over 3 years.

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Topic Detail

Market developments

How the market-driven The East Midlands has always had strengths in pharmaceuticals supply and R&D building on the heritage of Boots, Fisons, Ciba-Geigy and most recently Astra Zeneca and the West priority in the Midlands Midlands has exploited its engineering heritage to contribute significantly to the medical devices supply chain. Over the last decade a number of both product and supply led SMEs Engine has evolved have grown across the region from academic and commercial roots in particularly leveraging interfaces between the clinic and life sciences and engineering skills. Significantly a over the past five number of these SMEs have been acquired in trade sales both demonstrating the capability of the region and providing models for other regional entrepreneurs. The national years. reduction in and concentration of pharmaceutical R&D headcount has led to job losses, the most recent being AstraZeneca Charnwood. Earlier exits led to the creation of BioCity, Nottingham now nationally recognised as a leading bioscience incubator. Commercial, scientific and clinical drivers have increased our focus on growing medical technology and precision medicine, reflecting national trends while sustaining our activity in pharmaceuticals. The trend towards personalisation is bound to increase and will give increasing opportunities in diagnostics. The region has been particularly well placed to take advantage of the trend towards outsourcing which is reflected in the Midlands Engine’s strengths in service and supply chain across the pharma, biotech and medical technology sectors, with the region representing the largest cluster by employment in the UK (Strength & Opportunity 2015 data). The long medical technology heritage of the region also makes it well prepared for the challenges of escalating regulatory requirements in the sector.

The future prospects Medical technology is widely seen as a growth area, with compound annual growth rate of 12% in employment and 2% in revenue (In-vitro diagnostics have highest growth rate (7.5%) for growth in the in revenue of all life sciences). Products are high value and entry barriers to the industry can be high because of the regulatory hurdles making it attractive to mature locations. The market-driven priority, industry has traditionally been dominated by the US market because of its scale, consequently understanding the US product regulator, the FDA, has always been critical. The NHS in taking into account the UK focusses hard on cost-containment and is a difficult market, however because of this it has international leadership in the measurement of cost effectiveness via NICE, the wider market and National Institute of Clinical and Healthcare Excellence. It has also focussed on innovation, the Academic Health Sciences Networks being the current mechanism to promote technology changes. innovation in the NHS and on creating clinical trials infrastructure. The regulatory standards for medical devices have been rising for many years and will continue to rise. Significantly for the UK, post Brexit the European Medicines Agency (the EU regulatory body) is likely to move out of London. Given that the regulation of medical devices is delegated by the Agencies to “Notified Bodies”, locating a Notified Body to the region is an attractive strategy.

External perspectives

Key competitor regions The region has to recognise competition from the South East and the Golden Triangle of London, Cambridge and Oxford nationally for medical innovation both with respect to the in the UK concentration of science, and translation funding. The Crick Institute is London based as is the Cell Therapy Catapult with a £55M manufacturing led investment in Stevenage. PHE are relocating significant activity to Harlow, Essex. The Precision Medicines Catapult is Cambridge based and has a strong diagnostics focus. AstraZeneca are focusing their R&D in Cambridge, reflecting a concentration of pharmaceutical R&D investment in the SE including GSK. All are within easy reach of the Midlands Engine. The Northern Powerhouse also has strengths and ambitions in medical technology innovation with concentrations in Yorkshire and Alderley Park (another former Astra Zeneca R&D site) managed by BioCity, the Nottingham Incubator, as is a key Scottish incubator. The Midlands Engine therefore needs to complement and to enhance its bridges to these regions consequently emphasising medical technology and pharmaceuticals and also focussing on incubation and industrialisation to leverage our medical and life sciences capability by linking it to our engineering and manufacturing heritage, and our large population base and clinical trials expertise. Given the “best with best” requirements of national science funding and success in securing Innovate UK funding there are many linkages between the Midlands Engine science and innovation base with other regions nationally.

Key competitor regions Many regions internationally have a strategic focus on medical technology and pharmaceuticals as a consequence of the clear “health and wealth” benefits. Greater Boston is perhaps outside the UK the key leading cluster internationally exploiting the concentration of its clinical excellence with the research and innovation excellence of for example Harvard and MIT. Note that a significant part of Pfizer (UK) R&D has just relocated to Boston. There are a number of Boston links across the region and there are opportunities to enhance them as there are with the growing regional hub for medical technology in Singapore. Medicon Valley linking Denmark and Sweden and exploiting the clinical and translational excellence of Karolinska is an important competitor, nationally visible as the headquarters of AstraZeneca. However perhaps the most important competitor from a Midlands Engine and medical technology perspective is Ireland. The Irish have been pragmatically focusing on this area for a number of years with considerable success for instance in Galway, a major Boston Scientific location (Boston Scientific is the UK company that pioneered the stent – a benchmark medical technology innovation). The strength of the Irish cluster is of real concern for the UK as it is likely, post Brexit to be attractive for European Headquarters for US businesses in particular.

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Next Generation Transport

Topic Detail

Overview

Summary description of The Midlands Engine contains a critical mass of globally competitive businesses operating within and across a range of transport-related industries. Our business base covers the full the market-driven spectrum from R&D and design through to production and after sales service, and places us at the leading-edge of Next Generation Transport systems, vehicles and technologies priority globally. The Next Generation Transport priority is focused on opportunities within four distinct, but inter-related, sectors: Aerospace/Space; Automotive; Motorsport; and Rail.

Detailed description of Each of the four elements of our Next Generation Transport priority has its own specific circumstances as well as market and technology imperatives, but they are drawn together by a the market-driven set of shared high-level drivers of change and resulting challenges. These drivers include the greening of transport, global competition and customer demands, whilst the challenges priority, including focus on transport system integration, light weighting, optimised production and operation, and advanced propulsion, energy & power. identifying the relevant The four elements are also drawn together by shared technical expertise across the Midlands Engine in the following areas: industrial sub-sectors  simulation and modelling using high performance computing capabilities and scientific research areas  advanced digital design and physical validation to support ‘right-first-time’ design, reducing the need for testing and prototyping, and accelerating the development and deployment of novel technologies in future vehicles  advanced materials and manufacturing processes, with a focus in the Midlands on the application of advanced materials and processes such as composites and additive manufacturing to exploit fully the materials and processes most effectively  digital manufacturing, supply chain and service management including big data, supply chain management, intelligent automation and assembly, machining and condition monitoring, manufacturing metrology, metal precision manufacturing, responsive manufacturing, and advanced robotics.

Key elements of the Across the sectors of aerospace/space, automotive, high value motorsport, and rail, there are a number of technology areas where the Midlands Engine has particular strengths in our Midlands Engine ‘offer’ industrial and research base, where there will therefore be significant opportunities to drive productivity growth going forward. Examples of the significant expertise within the Midlands i.e. in what ways the Engine in the four technologies and disciplines identified above are given below: region is differentiated,  High performance system simulation and modelling: the Transport Systems Catapult’s Visualisation Laboratory demonstrates the power of a first person perspective in an specialised or accurately simulated environment. For example, users can walk round a virtual Milton Keynes populated with pedestrians and next generation autonomous vehicles, distinctive in the market-driven priority  Advanced digital design and physical validation: WMG’s 3D visualisation suite provides real time interactive immersive visualisation and virtual reality capabilities, allowing virtual inspections and physical user interaction to allow effective design decision making  Advanced materials and manufacturing processes: the MTC in partnership with University of Birmingham and MG Motor UK (and others outside the region) are part of the Innovate UK funded Automated Manufacturing Process Integrated with Intelligent Tooling Systems (AUTOMAN) project. This aims to develop a flexible panel manufacturing process based on digitally re-configurable tooling to produce high quality, 3D-functional, complex and lightweight panels. The MTC also worked with Rolls-Royce to develop a fully automated system for the manufacture of wax patterns for the turbine blade casting process.  Digital manufacturing, supply chain and service management: WMG’s Digital Lifecycle Management group conducts manufacturing systems research aimed at integrating products, processes and services with system design to create novel closed-loop production systems for the factories of the future. The management and reduction of environmental impact, including vehicle emissions and the impact on air quality, the impact of car greening, intelligent transport systems, and dynamic routing and data to support the green economy is also a significant growth opportunity for the region. The Midlands Engine ‘offer’ is also different from that of other regions, both nationally and internationally, because of the breadth and depth our research and innovation assets which are relevant to Next Generation Transport. These are explored more fully below.

Clusters, networks and linkages

The Midlands Engine is the UK’s leading region for manufacturing in transport technologies, with breadth across aerospace/space, automotive and rail sectors, and across the value Where in the Midlands chain from R&D and design through to production and post-sales servicing. Over 85,000 employees are supported in the region in ‘core’ transport manufacturing sectors, across all of Engine there are which the Midlands Engine has a LQ of over 1.0, reflecting our status as the driver of the UK’s transport sector. Although ‘core’ transport employment is pervasive across our geography, particular there are specific clusters of activity, such as Derby’s rail and aerospace clusters, and automotive in Coventry and Warwickshire and Greater Birmingham and Solihull. concentrations or clusters of businesses The motorsport element of Next Generation Transport is focussed on a spatially concentrated cluster of globally leading motorsport firms located around Silverstone in Northamptonshire, in the market-driven and centred around Northampton and Milton Keynes. The Midlands Engine is the spatial focus of a high performance technology and motorsport cluster (which also covers parts of priority Southern England) and has global leadership and international reach. Data indicate employment of around 23,400 in motorsport and its supply chain in the South East Midlands, with around 8,500 in Northamptonshire, giving an overall LQ of 1.16.

Evidence of Key examples of interactions include: interactions between

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Topic Detail businesses in the  The National Aerospace Technology Exploitation Programme brings together large customer companies in the region such as Rolls-Royce and United Technologies Corporation Midlands Engine in the with smaller companies interested in developing new technologies. Companies in the region are supported by the Midlands Aerospace Alliance through the process of defining market-driven priority projects, obtaining customer sponsorship and then managing the technology programme to completion. The programme has funded 114 projects nationally, many of which are in the Midlands and provided new opportunities to participating companies capture new business and generate their own intellectual property.  Automotive firms in the region are also members of the UK Automotive Council  Rail Forum East Midlands, formerly known as the Derby and Derbyshire Rail Forum (DDRF), that represents over 150 businesses across the East Midlands in the rail industry.  EMBRACE, the regional Centre of Excellence for the Satellite Applications Catapult, providing support to businesses in developing space enabled products and services. This is underpinned by expertise at universities of Leicester and Nottingham as well as British Geological Survey. The early stages of cluster development are evident and being supported through UKSA funding to three business incubator schemes in Leicester, Loughborough and Nottingham providing further support to emergent space enabled businesses.

With the Warwick Manufacturing Group and Tata Motors European Technical Centre, JLR has invested in the £150m National Automotive Innovation Centre (NAIC), which will open in 2017, providing a state-of-the-art facility for collaborative R&D. Rolls-Royce partnered with Loughborough University to research lean burn combustion for future aero engines. This collaboration has included the donation by Rolls-Royce of a test Evidence of rig and its installation and upgrading in Loughborough to carry out advanced testing and research for a range of purposes including teaching. This is an example of the long term interactions between partnering between Rolls-Royce and Universities across the region in University Technology Centres that carry out research, develop skills and provide a path for academic businesses and the excellence to be translated into industrially relevant technology and product innovation. Rolls-Royce has 19 such centres in the UK with 5 in the Midlands Engine region (Nottingham research base in the x2, Loughborough, Birmingham and Cranfield). Midlands Engine in the Birmingham University has pioneered novel methods of manufacturing ceramic turbine casting cores that reduce lead times by 25% and formed a long term partnership with Rolls- market-driven priority Royce on advanced high temperature materials resulting in a state of the art High Temperature Research Centre adjacent to the MTC: this proximity encourages collaboration in bringing early stage science and technology developed with the university up to industrial readiness and on to future deployment. Rolls-Royce subsidiary Control & Data Systems (CDS) partnered with a range of defence, electronics and aerospace companies and the Manufacturing Technology Centre in Coventry to develop and demonstrate new electronics components and assembly methods capable of withstanding very harsh environments.

Given the scale of the Next Generation Transport business and research base, links to outside the region arte extensive, some examples include:  The Manufacturing Technology Centre (MTC) and Warwick Manufacturing Group in the Midlands are part of the national High Value Manufacturing Catapult that also has its Headquarters in the region but brings together additional capabilities from centres in Bristol, Sheffield, Redcar and Strathclyde. Each centre specialises in a particular manufacturing technology (e.g. additive layer manufacturing at the MTC, composites in Bristol) but is also able to assist companies local to it with accessing the capabilities of Evidence of linkages the rest of the network. between organisations  The €5bn+ Clean Sky and Clean Sky 2 European research programmes are managed by a joint undertaking between the European aerospace industry and the European within the region and Commission. Rolls-Royce is a member of the joint undertaking, leading major engine technology demonstration programmes and contributing to whole aircraft studies. Much of key organisations this work is carried out in the Midlands at Rolls-Royce’s sites in Derby, Hucknall and Solihull. outside the region in  Many linkages to external organisations exist through University of Leicester collaborative projects, many of them funded by European Space Agency. Additionally Leicester the market-driven holds a £3.5m contract from the French Space agency (CNES) to develop instrumentation for the Chinese mission SVOM (Space Variable Objects Monitor) and holds the priority contract to devolve >£3M funding on behalf of the UKSA through its CEOI (Centre for Earth Instrumentation) programme in collaboration with Airbus , Qinetiq and SSTL (all organisations based outside the region)  The Advanced Propulsion Centre has its central hub in the region, and operates a hub-and-spoke model to spoke centres of technological excellence and facilities both within and outside the region e.g. Warwick (electrical energy storage), Nottingham (power electronics), Loughborough in London (digital engineering & test), Newcastle (electrical machines), Brighton and Bath (internal combustion engines).

Assets

The key research The Midlands Engine has a nationally unrivalled concentration of research and innovation assets in Next Generation Transport. In the industrial base, we have national/international centres, university R&D Centres for global companies including JLR, Rolls-Royce, Bombardier and SNC-Lavalin. departments, RTOs, Our universities participate in over half the EPSRC’s flagship Centres in Innovative Manufacturing, and we host five centres with direct relevance to Next Generation Transport: major private sector Intelligent Automation (at Loughborough University), Through-Life Engineering Services and Ultra Precision (both at Cranfield University), and Additive Manufacturing, and R&D facilities, NHS etc. Composites (both at Nottingham University). Our universities also lead six related EPSRC Centres for Doctoral Training in manufacturing, focused on Intelligent Automation, Metal that support the Processing, Additive Manufacturing, Composites, Sustainable Materials, and Low Environmental Impact Manufacturing, all of which are relevant to Next Generation Transport and formation and growth of which reflect our Advanced Manufacturing and Engineering Enabling Competences. businesses in the Other research centres include: the Institute for Aerospace Technology at The University of Nottingham; the Birmingham Centre for Railway Research and Education (one of only market-driven priority in three universities in the UK offering rail specific education programmes); Warwick Manufacturing Group (WMG); Coventry University’s Institute of Advanced Manufacturing and the Midlands Engine

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Topic Detail

Engineering; Cranfield University’s Institute for Vehicle Health Management; and a network of Rolls-Royce University Technology Centres in Materials (Birmingham), Performance (Cranfield), Combustion Aerodynamics and Aerothermal Technology (Loughborough), and Manufacturing Technology, and Gas Turbine Transmission Systems (Nottingham). RTOs in the Midlands Engine include: Manufacturing Technology Centre and Warwick Manufacturing Group (both part of the High Value Manufacturing Catapult), Transport Systems Catapult, MIRA Technology Park, Advanced Propulsion Centre Hub (Warwick), Network Rail's Rail Innovation and Development Centre (RIDC), Millbrook Proving Ground, Cranfield University – Aerospace Integration Research Centre, Aerospace Technology Institute, and EMBRACE (the East Midlands Satellite Applications Centre of Excellence).

Investment

The most significant Examples of key investment include: investments by the  The £150m National Automotive Innovation Centre supported by Jaguar Land Rover, Tata Motors European Technical Centre, WMG and the University of Warwick, and private sector in HEFCE. JLR has also invested £1bn into the Engine Manufacturing Centre at Wolverhampton, and £20m in the Special Vehicle Operations (SVO) technical centre in Coventry innovation and R&D activity in the Midlands  Infinity Park in Derby, a commercial and technology park including the ‘Centre for Supply Chain Innovation in Transport Engineering’, which will host ‘Enscite’, a collaboration Engine in the market- between the universities of Derby and Aston, and Derby City Council. It will provide access to cutting edge research and technology transfer expertise to supply chain companies driven priority in the aerospace, automotive and rail sectors  the National Transport Design Centre in Coventry, focusing on education in transport design, research projects in collaboration with industry, and support for the high-value manufacturing sector and its supply chain to improve design capability.  the UK Autodrive project, which is trialling self-driving vehicle and connected car technologies, culminating in a series of urban demonstrations in Milton Keynes and Coventry  Rolls-Royce leads its large engine development programmes from its site in Derby. Each programme represents a ~£1bn investment in R&D before entry into service and then decades of ongoing support thereafter. Much of this investment goes directly into Rolls-Royce’s sites in Derby, Hucknall and Solihull as well as the extensive development supply chain that exists around these sites. These programmes have delivered the globally successful Trent series of aero engines that have now achieved ~50% market share in the wide body market. Rolls-Royce also invests in four University Technology Centres in the region (at universities in Nottingham, Birmingham, Loughborough and Cranfield) that lead early stage research in the fields of gas turbine transmission systems and performance, manufacturing & on-wing care, combustions aerothermal processes and shared leadership of materials research.  HORIBA MIRA Ltd – a world-leader in advanced engineering, research and product testing – has benefitted from a total of £29m investment since joining the HORIBA Group one year ago; enabling ambitious plans for growth and an increase in staff. Investment included upgrades to a number of its existing facilities, including its world-class crash testing capabilities and wind tunnels, along with new additions to the site including the Advanced Emissions Test Centre, which is due for completion in early 2017. In addition, HORIBA MIRA has completed Phase One of its Technology Park development which is a flagship location for automotive R&D investment.

The most significant Data provided by UKTI indicates that in 2015/16, the Midlands Engine (defined as the regions of the West Midlands and East Midlands) secured 62 inward investment projects in the inward investments into broad sector of ‘Transport’, supporting some 8,450 jobs. the region in the Reflecting the importance of the Market Priority to the regional economy, ‘Transport’ accounted for one in five of all inward investment projects recorded by UKTI in the region in Midlands Engine in the 2015/16, and 30% of all jobs. market-driven priority

Market developments

How the market-driven The four elements within our Next Generation Transport priority are responding to the same overarching drivers of change. These include: priority in the Midlands  The Greening of Transport - With an ever greater appetite for travel and need for the effective mobility of goods and people to support economic growth, measures are Engine has evolved increasingly being taken to curb the potential harmful effects from CO2 emission reduction targets through to measures for NOx and noise. These step changes require over the past five advanced, integrated technologies and novel approaches to be deployed by infrastructure providers, manufacturers, institutions and end users. years.  Global Competition - Transport sectors are fiercely competitive global industries, in which the pace of innovation and focus on meeting changing customer needs is incredibly high. New product introduction and upgrade cycles are accelerating, and while the physical performance attributes of products (e.g. capacity, power, weight, strength and temperature tolerance) remain crucial, deploying digital capabilities across the product lifecycle is becoming the new competitive differentiator for the products, systems and services future transport demands.  Customer Demands - A requirement in any transport environment is ‘no surprises’. Users expect absolute reliability, safety and predictability, alongside convenience, better performance, lower cost, new functionality and good connectivity. Increasingly, the desire for ‘on-demand’ transport or propulsion is shifting the onus of operational risk and asset management onto the product/service provider. Delivering this while pushing the boundaries of technology demands closely coupled processes capable of translating new innovation and technologies into trustworthy products and services with minimum lag and waste.

The future prospects Evidence from a review of the literature on the future prospects for the priority area suggests: for growth in the  The global volume of air traffic is expected to increase to 16bn passengers annually in 2050 whilst the large civil airliner market is forecast to be worth $3.2tn by 2030 market-driven priority,

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Topic Detail taking into account  Global automotive sales are forecast to be 111m units by 2020. Within this, autonomous driving technology global sales are predicted to grow five-fold to €35.7bn by 2020, with wider market and sales of safety technologies to quadruple to €47.3bn between 2015 and 2020 technology changes.  The global rail market is forecast to be worth £128bn by 2019

External perspectives

Key competitor regions For aerospace, the other UK regions that are highly active are mainly the South-West (Airbus wings & landing gear, GKN composites & systems, Leonardo helicopters & Rolls-Royce in the UK defence & manufacturing), North West & North Wales (Airbus wings, BAE Systems defence) and Northern Ireland (airframes). There are many linkages between these regions with some large companies having a presence in more than one region (e.g. Airbus, BAE Systems, Rolls-Royce) and buying from suppliers in many regions. Many companies are members of the nation trade association, ADS and also of regional trade associations including the Midlands Aerospace Alliance. There are over 30 key automotive manufacturing sites within the UK, most of which are located within the Midlands. Outside the Midlands, there is a particularly high concentration of automotive manufacturing sites in the North East (e.g. Nissan in Sunderland, Cummins in Darlington), North West (e.g. Vauxhall in Ellesmere Port, Bentley in Crewe), and in London and the South East (e.g. Ford in Bridgend and Dagenham, Maclaren Automotive in Woking). The Midlands is the heart of the UK’s rail industry; other centres of manufacturing and innovation in rail include Swindon and Wiltshire and Greater Manchester, but both are far smaller in terms of direct employment than Derby, Derbyshire, Nottingham and Nottinghamshire. Notably, Hitachi recently opened a new Rail Vehicle Manufacturing facility in County Durham, which will drive their future growth in Europe supported by their European Rail Research Centre HQ in London. The rail supply sector is located across the UK with locations following rail routes and particular concentrations in the Midlands, North and South East.3 Key competitor regions in the space sector include Harwell, which is home to the Satellite Applications Catapult and multiple other space related businesses and organisations, Scotland (Clyde Space) and Cornwall (Goonhilly Earth Station and lobbying for a UK space port at Newquay). The ME is certainly smaller than the Harwell cluster but is on a strongly upward trajectory with three space incubators within the region, the home to the regional centre of excellence and Leicester’s plans for a National Space Park, the latter supported by the catapult and Innovate UK and with key industrial players on board.

Key competitor regions Outside of the UK, key prime and tier 1 competitor regions in aerospace are in the US (e.g. Washington state for Boeing, Ohio for GE Aviation, Connecticut for Pratt & Whitney), outside the UK Germany (Munich for MTU Aeroengines), France (many locations for Safran Aero Engines). China has recently announced the formation of its own integrated aero engine company, its HQ is in Beijing but it has many subsidiaries all over China. There are a number of other aerospace clusters in mainland Europe (including Poland’s ‘aviation valley’ in Podkarpackie Voivodeship). There are also emerging clusters in the Middle East, India and South-East Asia where Singapore in particular aims to attract aerospace projects with a similar profile to those the UK wants to attract (i.e. high technology R&D and advanced manufacturing). Rolls-Royce has connections to many of the leading global aerospace regions through its supply chain as well as its own aerospace operations in the U.S. (Indiana and Virginia), Germany (Brandenburg & Hesse) and Singapore. Onrail other countries, most notably France and Germany, are recognised for their export success, built on strong indigenous tier one manufacturers and ambitious national railways.4 On automotive, Japanese firm Toyota (including the Daihatsu and Hino brands) is the world’s largest vehicle manufacturer by sales, selling 10.15m units in 2015. Toyota has a manufacturing plant in Burnaston, Derbyshire, and California based firm Tesla is at the forefront of innovation in electric and connected/semi-autonomous vehicles, whilst driverless taxis are already being trialled in Singapore. Further, analysis suggests that by 2021, nearly 3 million cars will be built yearly in the Middle East and Africa (especially Algeria, Nigeria, Egypt, and Iran), an increase of 50.

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Energy and Low Carbon

Topic Detail

Overview

Summary description of The Midlands is at the heart of the UK’s energy system, with expertise and capability across a diverse range of areas from conventional energy supply and distribution, through to the market-driven renewables and low carbon technologies. Within this significant and broad sector, informed by emerging green energy and energy efficiency drivers of change, the SIA has identified priority five interrelated sub-elements that form the Energy and Low Carbon Technologies Market Priority Area.

Detailed description of  Geo Energy: UK leadership in Geo Energy is provided by The British Geological Survey (BGS), which has its HQ near Nottingham, with expertise in the development of the market-driven renewable energy such as geothermal power, carbon capture and storage, and unconventional hydrocarbon and coal resource development priority, including  Thermal Energy Systems: Research institutions across the region are working nationally and internationally with industry on topics as diverse as metallurgy, materials, identifying the relevant industrial process engineering and control, bio-fuels, bio-energy systems, and cryogenics industrial sub-sectors and scientific research  Nuclear: Opportunities are evident in the management of nuclear waste and decommissioning, and the development of small modular reactors that can provide additional areas capacity adding to and complementing the current plans for large nuclear plants. The Midlands has many companies involved in nuclear systems design and construction, including Rolls-Royce, who have delivered many reactor systems for the UK submarine fleet  Energy Storage: The Midlands is working on a very wide range of potential energy storage systems in conjunction with industry including battery technologies (materials and chemistry); Hydrogen; Compressed Air; Molten Salt; Geo systems and Cryogenic systems (Nitrogen, Air and Hydrogen). These Energy storage systems have relevance to the decarbonisation of transport systems, the domestic sector, integration with solar systems and grid level storage to complement intermittent renewable energy sources.  Smart Integrated Energy Systems: Innovation opportunities to exploit smart systems exist largely at the point of use and 'behind the meter' in the consumer's home or premises. Vital research and industrial capabilities which sustain innovation will be in sensors, controls, communications, data (including the architectures which will enable them to be deployed effectively), power systems, and modelling and simulation capabilities to analyse system behaviour under change, and the Midlands is leading demonstration level research on energy efficiency issues including human interactions inside and outside the home with significant commercial potential. There are strong synergies between this Market Driven Priority and other parts of the SIA Framework. For example, Energy and Low Carbon Technologies aligns closely with Next Generation Transport, in the areas of low-carbon vehicles, and in research and industrial capabilities on the design, integration and control of electrical power systems.

Key elements of the The Midlands Engine contains a critical mass of innovation assets in Energy and Low Carbon including the Energy Research Accelerator and the Energy Systems Catapult based in Midlands Engine ‘offer’ the region, over 500 academics and scientists working in energy across the region’s universities and scientific institutions, and leading research across our university base; global i.e. in what ways the energy businesses such as Alstom, Cummins, EoN and their new formed technology arm at Uniper, GE, Jaguar Land Rover, National Grid, Rolls-Royce and Siemens, and many region is differentiated, innovative SME's including Bladon Jets, Ekkosense, Lindhurst Engineering, and Intelligent Energy; and a network of existing or pipeline demonstrators (both research and industrial specialised or capacity) which have the potential to support the integration of future smart energy system technologies into infrastructure. distinctive in the market-driven priority

Clusters, networks and linkages

Where in the Midlands The Energy sector and relevant supporting technical disciplines support around 180,000 work-based employees across the region; including over 28,000 employees in ‘Electricity, Engine there are gas, steam and air conditioning supply’ (with an LQ of 1.4 indicating an overrepresentation in the Midlands Engine). The next most significant sector in employment terms is ‘Waste particular collection, treatment and disposal activities; materials recovery’ with an employment of around 22,000. concentrations or There are particular concentrations of employment in Birmingham and Nottingham, but significant employment in energy and supporting disciplines is evident across the region and its clusters of businesses local areas. in the market-driven priority

Evidence of Examples of interactions include: interactions between  E.ON Technologies and Alstom are working together as part of the Innovate UK £550k IMPACT project to improve the efficiency of future steel-based coal-fired power plant, and businesses in the hence reduce carbon emissions. Midlands Engine in the market-driven priority  Intelligent Energy worked with Conekt, Ricardo and Dyson on the Enhanced fuel cell systems for real world commercial and passenger vehicle applications project.  Greenbank Group is working with the University of Nottingham and Argenta Consulting on a £150k Intelligent Flow Control System project funded by Innovate UK.

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Evidence of There are many instances of collaborations between the businesses and the science base. Significant exemplars are: interactions between  Developing "The GenGame" domestic smart grid platform - a three-year project funded by Innovate UK is led by Oswald Consultancy Ltd, a Warwickshire based engineering firm, businesses and the working alongside the Serious Games Institute at Coventry University, Leicestershire-based Jaamacoe Solutions and partners outside the region. The project is exploring the long research base in the term opportunity for domestic householders to trade appliance load curtailments via an online ‘serious game.’ Midlands Engine in the market-driven priority  Transvac Systems Limited and the University of Nottingham are working on Multistage Ejectors for Flare Gas Recovery using approximately of £160k of Innovate UK funding. The region also supports a wide range of activity funded through the Energy Research Accelerator by Innovate UK, including  Integrated Energy Systems Research Accelerator (I-ERA) – The University of Warwick is working with Jaguar Land Rover to conduct research on battery chemistry, second life batteries, lighter weight car batteries and to deliver the National Low Carbon Mobility Centre  Thermal Energy Research Accelerator (T-ERA) – The Universities of Aston, Birmingham, Warwick and Loughborough are working with the Dearman Engine Company, Highview Power Storage and Cofely (Engie) to deliver a scaled up liquid nitrogen engine, the Advanced Thermal Manufacturing Centre and research into delivering hydrogen from biomass as well as 600 GWh of combined green power and heat across Birmingham.  Geo Energy Research Accelerator (G-ERA) – Working with Schlumberger and the Royal Engineers, the University of Nottingham and the British Geological Survey will deliver a new geo-energy test bed facility for underground monitoring technology testing; a hydrogen systems test bed focused on researching lower cost, safe and integrated hydrogen systems; the Gaseous Research Acceleration and Demonstration Centre to examine energy storage, energy systems and next-generation carbon capture and transport. G-ERA will also work with Blueprint to deliver the Trent Basin Development in Nottingham which will hold 250 of next generation energy efficient homes at its site.

Evidence of linkages Key examples of links between organisation in the region and other areas in the Energy and Low Carbon space include: between organisations  Aston University’s European Bioenergy Research Institute (EBRI) - EBRI is now a lead on the European Energy Research Alliance Bioenergy Joint Research Programme; is part of within the region and the International Energy Agency’s Bioenergy Task 34 for Pyrolysis and is a member of Bioenergy North West Europe. key organisations outside the region in  University of Birmingham - Successful establishment of a joint laboratory with the State Grid Corporation of China and the Global Energy interconnection Research Institute Europe the market-driven on Energy Storage Research. The University also signed Memorandum of Understanding with Chinese organisation General Nuclear International Ltd to forge a long-term priority partnership in the education, training and development of civil nuclear energy studies. In 2015, the University of Science and Technology Beijing launched a new joint Centre for Energy and Environment Research and Education (CEERE) to drive new technologies and train the next generation of engineers.  University of Nottingham has established links with the Malaysian Ministry of Science, Technology and Innovation, the Ministry of Higher Education and industry partners. These links have played a key role in the development of the University of Nottingham’s Department for Energy, Fuel and Power Technology based on its Malaysia campus.  Warwick Manufacturing Group (WMG) was instrumental in setting up a major collaborative research programme with Tata Steel and three leading Indian Institutes of Technology in Kharagpur, Guwahati and Bhubaneswar. This partnership addressed opportunities in four areas: steel forming technologies, advanced assembly techniques, hybrid and multi- material lightweight solutions, and optimisation of performance.

The key start-ups in the Innovative SME's based in the Midlands Engine include: Midlands Engine in  Bladon Jets which is pioneering the development of micro gas turbines – small, light and clean-burning jet engines which will provide a new generation of green and efficient recent years in the power units. market-driven priority, and why they are  Ekkosense which has world class thermal and cooling expertise important  Lindhurst Engineering which provides bespoke design and manufacture in sectors such as utilities and low carbon  Power technology company Intelligent Energy which specialises in the development of fuel cells for the automotive, consumer electronics and stationary power markets.

Assets

The key research Key assets include: the British Geological Survey (BGS), headquartered in Keyworth, a world leading geological survey and the UK's premier provider of objective and authoritative centres, university geoscientific data, information and knowledge for wealth creation, sustainable use of natural resources, reducing risk and living with the impacts of environmental change; the Centre departments, RTOs, of Excellence for Low Carbon and Fuel Cell Technologies, in Loughborough, an independent not-for-profit consultancy specialising in the delivery of projects, innovation and market major private sector development with a direct focus on low carbon vehicles and associated energy infrastructure; the Energy Research Accelerator (ERA ) a cross-disciplinary energy innovation hub R&D facilities, NHS etc. which brings together capital assets, data and intellectual leadership to foster collaboration between academia and business to accelerate the development of solutions to the global that support the energy challenge; the Energy Systems Catapult, based in Birmingham, that leads on the UK’s analysis of future requirements for the energy sector, many of which will involve formation and growth of exploitation of smart systems and executes innovation projects focussed on delivery of smart heat services to domestic consumers businesses in the The region also hosts demonstrators with the potential to support the integration of future smart energy system technologies into infrastructure, including: the Birmingham Thermal market-driven priority in Belt, the Community Energy Demonstrator at the Trent Basin, the Energy Security and Innovation Observing System for the Subsurface (ESIOS), the Geo-Energy Test Bed based at the Midlands Engine the University of Nottingham's Sutton Bonington campus and the Smarter Network Storage project at Leighton Buzzard, In addition, a Smart Energy Network Demonstrator is planned at Keele University.

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Key university research centres include: European Bioenergy Research Institute (Aston); Birmingham Energy Institute, Centre for Nuclear Education and Research, the Highview Cryogenic Energy Storage Pilot Plant, and the EPSRC Centre for Doctoral Training in Fuel Cells and their Fuels (Birmingham); Bioenergy and Resource Management; Combustion, Carbon Capture and Storage, Offshore Renewable Energy, Oil and Gas Engineering (Cranfield); Siemens’ Research Centre at Keele; Earth Observation Group at Leicester; Centre for Renewable Energy Systems Technology and the EPSRC Supergen SuperSolar Hub (Loughborough); Energy Technologies Research Institute, collaborations with BGS on the GeoEnergy Research Centre and Centre for Environmental Geochemistry. The University hosts the EPSRC Centre for Power Electronics, and the Centre for Doctoral Training in Carbon Capture and Storage and Clean Fossil Energy (Nottingham); and WMG and part of the national Centre for Power Electronics (Warwick). The business base in the region includes major sites of global energy businesses such as Alstom, Cummins, E.ON and their new formed technology arm at Uniper, GE, Jaguar Land Rover, National Grid, Rolls-Royce and Siemens.

Investment

The most significant The region has benefited from significant investment via the £180m Energy Research Accelerator (ERA). This includes: £60m Government capital investment; £100m of co-finance investments by the from private companies; and £20m from the Midlands Innovation universities. The universities and EPSRC have committed another £2.4 million to recruit 33 doctoral students and the private sector in ERA’s research funding portfolio is £71.7m (EPSRC). innovation and R&D The region also benefited from earlier investment of some £550m in the Energy Technologies Institute. Established in Loughborough during 2006 the ETI is a 50:50 partnership activity in the Midlands between UK Government funding and five major industry members: BP, Caterpillar, EDF Energy, Rolls-Royce and Shell. The ETI, due to end in 2019 acts as a conduit between Engine in the market- academia, industry and the government to accelerate the development of low carbon technologies. ETI brings together engineering projects that develop affordable, secure and driven priority sustainable technologies to help the UK address its long term emissions reductions targets as well as delivering nearer term benefits.

The most significant Data from UKTI identified eight inward investment projects into the region in Energy in 2015/16, supporting over 450 jobs. inward investments into the region in the Midlands Engine in the market-driven priority

Market developments

How the market-driven Key headline drivers of change for each sub-element of the priority are presented below. priority in the Midlands  The UK's natural resources are declining and will only be partially replaced by indigenous renewables, creating a need for alternative renewable energy resources such as Geo Engine has evolved Energy and Nuclear Energy. The civil nuclear industry will play a key role in the UK’s energy mix going forward, with no viable alternative for clean electricity on demand as over the past five base load. Opportunities are evident in the management of nuclear waste and decommissioning, and the development of small modular reactors that can provide additional years. capacity adding to and complementing the current plans for large nuclear plants.  There is a growing market demand for the decarbonisation of thermal energy systems and their integration with the remainder of the energy system.  Energy Storage: will support smart integrated energy systems and enable previously isolated components of the energy system to work together (electricity, gas and heat).  Smart Integrated Energy Systems: present substantial innovation opportunities in the UK and internationally. They support optimisation of investments in renewing energy infrastructure and re-configuration of value-chains to allow the delivery of new energy services to consumers.

The future prospects  Global electricity demand is projected to increase by 85 percent between 2010 and 2040 for growth in the  World electricity generation is forecast to grow by 70% from 22,126 terawatt-hour (TWh) in 2011 to 37,000TWh in 2030 market-driven priority, taking into account  Global investment in the power sector of $21tn up to 2040 is predicted, with over 40% of this in transmission and distribution networks wider market and  The worldwide energy storage market is expected to quadruple to $6bn by 2020 technology changes.

External perspectives

Key competitor regions There are concentrations of employment in the energy sector throughout the UK. Notable examples include Cumbria (employment of 17k, location quotient of 1.9) and Scotland (143k, in the UK 1.5). Other examples at LEP level include the Enterprise M3 LEP (47k, 1.6), Tees Valley (15k, 1.5) and Greater Cambridge and Greater Peterborough (37k, 1.5). The high concentration of employment in Cumbria is linked to the strength of the nuclear industry across the North West of England. Key sites in the North West are Sellafield and Moorside (Cumbria), Heysham and Springfields (Lancashire), Capenhurst and Birchwood (Cheshire) and Greater Manchester [the Witty Review identifies nuclear publications from the University of Manchester as ranking third in the UK, both in terms of volume and field weighted citation impact]. Looking more widely, the Nuclear Industry Association identifies key employment locations at Hinkley Point (Somerset), Sizewell (East Suffolk) and the Culham Centre for Fusion Energy (Oxfordshire).5

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On Energy Storage, the Witty Review identifies the Golden Triangle as the leading area for research: the Universities of Oxford, Cambridge, and Imperial College London are the top three for field weighted citation impact (with University College London ranked 6th). In industrial terms, the largest operational energy storage projects in the UK are in Wales (Dinorwig Power Station and Ffestiniog Pumped Hydro Power Plant) and Scotland (Cruachan Power Station and Foyers Pumped Storage Power Station).6 These projects are strongly linked to renewable energy, an area in which Scotland is leading with the devolved administration’s target to generate 100% of energy from renewable sources by 2020.Offshore wind is a particular strength with a “strong concentration” of the sector in Scotland, including industrial players Samsung, Mitsubishi and Siemens.7 Wider research strengths in Scotland in this area include the world’s only combined wave and current test facility (University of Edinburgh) and the European Marine Energy Centre (Orkney) which is the only wave and tidal device testing centre of its kind in the world.8

Key competitor regions In nuclear energy, France has the largest share of power generated by nuclear energy (76.3%) and the second highest number of operated reactors (58) in the world. The United outside the UK States has the highest number of nuclear reactors (99), but their share of energy generation is lower at 19.5%9. Going forward, China is predicted to account for around 45% of growth in nuclear generation to 204010. Nuclear power is also a key part of the Indian infrastructure development plan, with negotiations underway to unlock long-standing agreements with French, Russian and US companies to build nuclear power plants in the country. Unit 2 of a Russian-built nuclear power plant in Tamil Nadu is nearing commissioning and a prototype fast breeder reactor is nearing completion near Chennai11. In energy storage - Several countries have recognised the potential of energy storage technologies and developed supporting policies. Examples include the ‘Storage Technology for Renewable and Green Energy Act of 2013’ in United states and the ‘stoRE’ project in EU12. The Japanese government is also supportive and has offered utility companies incentives to add energy storage, as well as providing grants for residential storage deployment13. Companies entering the energy storage market include General Electric and NEC Energy, Stem and Green Charge Networks14. Japanese giants Toshiba and Panasonic and South Korean conglomerates Samsung and LG are leaders in the fast-growing battery energy storage market for power generated from renewable sources15. Nissan, AESC, GS Yuasa and BYD are concentrating on the market for battery-powered electric vehicles16. In the broad area of renewable energy and research, although Europe has traditionally been an important centre for innovation, recent activity has shifted to regions including China, Brazil and India, with China ranked highest in new power capacity installation in 201417. Onshore wind leads the growth in renewables, accounting for over one-third of the renewable capacity and generation increase18. Recently, China’s Goldwind became the world’s largest wind turbine maker19 whilst Siemens is the lead offshore wind turbine supplier in Europe20. Other major global wind turbine manufacturers include General Electric (US) and Vestas (Denmark).

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Annex I: E-consultation responses

This section summarises the results of the e-consultation exercise run for three weeks between 29th June and 20th July. There were 98 unique, completed responses to the e-consultation. In total, 47 named organisations and two unidentified organisations responded to the survey. The majority of responses were from HEIs (50), with a further 22 from LEPs, councils and other public bodies. Some 17 responses were received from businesses, in addition to three from sector bodies and one from a social enterprise.

E-consultation responses by Theme

Responses Organisations Advanced manufacturing and engineering 10 9

Agri-food and drink manufacturing and production 10 10

Creative, digital and design sector 14 11

Energy and low carbon technologies 16 15

Healthcare, life sciences and translational medicine 15 13

Transport technologies 17 15

Cross thematic 16 15

Total 98 47(+2 unidentified)21 Source: SQW analysis

Care must be taken in interpreting these responses not only because of the relatively small number, but also because many respondents found it difficult to provide a Midlands Engine wide view, and instead focussed their answers on strengths/assets/opportunities which were particularly relevant to their own organisation/LEP area.

The remainder of this section presents and analyses responses on specific areas of strength, opportunities for the future, and networks that respondents are part of. The assets and key large and small businesses identified by respondents have been included in the asset register present above in Annex E.

Specific areas of focus (including capabilities and sub-sector specialisms)

Respondents were asked to identify up to three areas of focus where the Midlands Engine geography currently possess, or has the potential to develop, globally competitive scientific research and/or innovation strengths.

Advanced manufacturing and engineering

The most commonly identified current strength was around automotive and motorsport (four respondents out of ten), whilst the aerospace and space industry were also highlighted by multiple respondents (two each). Individual respondents also cited areas such as polymers and rubber, optical communications and additive manufacturing.

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In comparison, the potential future strengths identified focussed more around advanced manufacturing techniques such as additive manufacturing, digital manufacturing, automated manufacturing, advanced textiles processing and composites.

Automotive – “High levels of original equipment manufacturer FDI and R&D investment e.g. JLR; strong collaborations between industry and research institutions (HEI and public/private e.g. MTC and WMG); plus leading UK levels of supply chain FDI” Space – “[University of Leicester has a] 56-year history in space research and engineering including the complete life cycle of design, build test, flight, science and application of instruments and sensors on many international missions. It is a regional centre of excellence for the Satellite Applications Catapult and the National Centre for Earth Observation is based at Leicester”

Agri-food and drink manufacturing and production

Current strengths were identified across the whole sector, ranging from production to processing and manufacturing through to packing and onto logistics and distribution. Indeed, one respondent commented that “the region contains strength in the whole food chain from field to fork.” However, there was no clear consensus amongst respondents as to which parts of this chain were the strongest. Areas that were highlighted included farm animal science, food engineering, crop science, earth observation for precision agriculture, food quality and primary food production.

Similarly, areas of potential future strength were identified across the supply chain. These included precision agriculture, food engineering and flavour science, the health agenda and new products, and consumer science. Process intensification, packaging and microbial sciences for food safety were also identified.

Food manufacturing – “Nottingham, Birmingham and Loughborough Universities are the collaborating institutes in the EPSRC Centre for Innovative Manufacturing in Food. University of Lincoln is the home to National Centre for Food Manufacturing” Food processing and production – “innovative food production and processing companies in Greater Birmingham e.g. Mondelez, Nestle and Brunei Halal”

Creative, digital and design sector

Responses from the creative and design elements of the Theme highlighted textiles (covering design, fashion, and intelligent textiles) and museum exhibition design (three responses each, from a total of 14 responses) as current strengths of the ME area. More digitally focussed responses cited cyber security, gaming and data analysis (two responses each) as areas in which the ME is currently strong.

Similar areas were identified as potential future strengths, with both cyber security, and fashion and textiles cited by multiple respondents. Other areas identified included fintech, the fashion and textiles supply chain, specialist design and craft skills, and film and broadcast media.

Computing and big data – “Both Loughborough and Leicester universities possess world class/leading applications in computer science, and IBM Cloud Computing are based in Leicester”

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Fashion and textiles – “Some of the most creative fashion designers are in the East Midlands, serving fast fashion e.g. ASOS and Next are reshoring for fast fashion as are some industrial textiles producers for medical and safety applications.” Museums - Award winning research on museums, visitor experience and the role of cultural values [at the University of Leicester]”

Energy and low carbon technologies

Commonly cited areas were energy storage and low carbon housing (both four respondents out of 16) and bioenergy and biofuels (three respondents). Other strengths were identified in thermal energy, energy systems and low carbon vehicles (all had two respondents). Cyber security, nuclear energy and power transmission were also cited.

Future strengths reflected current strengths with low carbon housing and energy storage both prominent (three respondents each). Energy systems, bioenergy and nuclear were also commonly cited (two responses each), with thermal energy and low carbon vehicles also identified.

Bioenergy – “Excellent chemical engineering capability at Aston (EBRI) Harper Adams Anaerobic Digester; Tyseley Energy Park; work at Nottingham Trent” Energy storage - “Earlier stage energy storage research at Nottingham (mechanical storage i.e. compressed air), Warwick (batteries) and Birmingham (liquid air storage) provides insights to market developments”

Healthcare, life sciences and translational medicine

Current strengths were identified across the whole Theme, ranging from translational medicine to clinical trials, ophthalmic research and engineering to medical technologies, and regenerative medicine to digital health. Single respondents also cited defence medicine and precision medicine as current strengths. The same areas were also suggested as being potentially significant in the future but there was no consensus on which would be the most significant.

Clinical trials - “Access to the diverse but stable nature of the region’s population and range of environments (both dense urban areas and rural locations)” Medical technologies - “The Midlands has the UK's largest cluster of medical technologies companies” Translational medicine - “The midlands has a strong academic base engaged in translational medicine evidenced by high impact journal publications, intellectual property filings and synthesis of spin outs”

Transport technologies

There was a clear consensus on current strengths: automotive, including low carbon and fuel cell technology (seven respondents out of 17); and aerospace (five respondents). Three respondents cited rail, including rolling stock and rail engineering, as another area of strength. Propulsion systems were also cited as a strength.

Future areas of strength were expected to build on current strengths, for example the development of autonomous vehicles and the electrification of transport. The cross over between more traditional transport strengths and emerging areas of activity such as intelligent

100 Science and Innovation Audit Volume 2: Supporting Annexes mobility, systems integration, digital design, smart sensors, and the use of big data were also highlighted.

Aerospace – “Home to globally leading companies with system level integration capability (e.g. Rolls-RoyceRolls-Royce), supply chain, and world class universities (e.g. Nottingham) with significant proven infrastructure and collaboration experience” Automotive – “High levels of original equipment manufacturer FDI and R&D investment e.g. JLR; strong collaborations between industry and research institutions (HEI and public/private e.g. MTC and WMG); plus leading UK levels of supply chain FDI”

Opportunities

Respondents were asked what they considered to be the single most important opportunity for economic growth in the Midlands Engine, rooted in science and/or innovation.

Advanced manufacturing and engineering

Due to the breadth of the advanced manufacturing and engineering capabilities of the ME geography, a diverse set of opportunities for economic growth were identified. These ranged from digital technologies for manufacturing and exploiting space based engineering, through to advanced laser processing and photonic technologies. Other responses including taking advantage of Industry 4.0 and the emerging electric car industry.

Digital technologies for manufacturing – “With its research and industry base the Midlands is well placed to develop major digital manufacturing demonstrators in support of the national Digital Technologies for Manufacturing Innovation (DTMI) initiative.” Exploitation of space based engineering and knowledge – “to applications varying from air quality through to medical devices. This includes manufacturing, development and characterisation of high performance materials, electronics and software. Based upon utilisation of lightweight, low mass and reliable systems derived from Space based activities and technologies.” Funding to support innovation – “Past evidence shows that old style sector thinking is probably unhelpful. Although the ME AME sector is "type cast" by automotive the strength in depth is cross sectoral approaches creating new production processes in many sectors. There is a funding gap which the ME Financial Instruments needs to address.”

Agri-food and drink manufacturing and production

The two most commonly identified opportunities were around precision agriculture, including automation and manufacturing efficiencies (three responses out of ten), and food systems (two responses). Opportunities in urban agriculture and strengthening the science base were also suggested.

Food systems – “The stronghold of active and leading Universities in the area, with very close connections with multinationals, but also local production means that this would provide a new approach to healthy and sustainable food production” Precision farming – “This will bring together advanced engineering and manufacturing to support the UK's food production system to increase efficiency and productivity and reduce environmental impacts.”

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Creative, digital and design sector

Reflecting the breadth of the Theme, a wide range of opportunities were cited, including digital health, FinTech and data analytics, creative industries, advanced manufacturing in fashion, and big data and the Internet of Things.

Creative industries – “computing/creativity/arts intersection can make the region world leading” Fashion – “With the adoption of mass customisation combined with digital sizing, compatible with the trend to online purchase, the sector has potential for global growth” Internet of Things (IoT) – “The IoT will provide a structure for connecting many datasets, including personal data, location data, commercial and government datasets. In doing so however, it will present a unique opportunity for cyber-criminals, and therefore will necessitate a significant upscaling of the provision of security. This is likely to lead to rapid growth in the market”

Energy and low carbon technologies

Energy efficient housing (including retrofitting and smart energy networks) and low carbon transport were the most commonly identified opportunities here (cited by four and two respondents, respectively). Other opportunities identified were the effective utilisation of waste, unconventional gas, building on the Energy Research Accelerator and the Smart Energy Network Demonstrator at Keele.

Domestic building retrofit – “There are 4.2 homes in the Midlands spending £1,250 each on fuel - £5.25 bn pa. This will need to be reduced by at least 60% by 2040. It's not just technology, although this is important, but it needs to align people and finance too. How do we make this desirable for householders? Answer that, and you can have the prize - a retrofit industry worth hundreds of millions per year for two to three decades” Low carbon (autonomous) vehicles – “By creating more efficient, autonomous, low carbon vehicles, these vehicles can use less fuel, last longer and provide better service, ultimately improving the national and global vehicle manufacturing economy”

Healthcare, life sciences and translational medicine

Several opportunities were identified which ranged from the very specific, e.g. developing a Life Science Opportunity Zone at Charnwood Campus, to the more general such as focussing on the areas of precision medicine or drug and device development. Translating research into clinical practice (in general or in relation to eye care in particular) and encouraging innovation and early adoption in the NHS was another broad opportunity identified.

Drug and device development - “The region can provide the total requirement from concept to product: academic input, NHS trusts, manufacturing capability, patient populations” Life Science Opportunity Zone at Charnwood Campus – “With a marketing and development strategy combining facilities and experience…along with access to the NHS facilities of the Nottingham, Derby and Leicester hospitals and universities, the Midlands could produce an identity to rival Oxford/Cambridge nationally and internationally and encourage business location and investment” Precision medicine - “The global market for population specific health solutions is predicted to grow by $900bn over the next ten years and Greater Birmingham has serious potential to leverage its existing strengths and assets to secure major investment opportunities arising from this expanding global market”

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Transport technologies

A range of opportunities were presented, many of which fit under the broad heading of next generation transport: connected and autonomous vehicles, digital railway, vehicle electrification, low-carbon energy supply chains for transport applications, and smart transport systems.

“Electrification technology capability is clear, and economic growth is a real possibility through supply chain, infrastructure and skills development. This applies equally to aerospace and automotive, both of which have a very strong industrial presence in the region. The market in both sectors is ready for increased electrification and all the elements for economic growth therefore exist in the region.

Networks

Respondents were asked what their own organisation’s three most important scientific research and/or innovation partnerships/relationships with others in the Midlands Engine area were. They were also asked about their three most important partnerships with organisations outside the Midlands Engine.

Advanced manufacturing and engineering

Partners identified within the ME were either universities (Birmingham, Loughborough, Nottingham), other research organisations (Transport Systems and High Value Manufacturing Catapults), businesses (Rolls-RoyceRolls-Royce, Laing O’Rourke) or networks (Midlands Innovation, High Performance Technology Forum).

Partners outside the ME included the National Composites Centre, European Space Energy, Mitsubishi, and Novosibirsk State University, showing the global reach of survey respondents

Agri-food and drink manufacturing and production

The Centre for Innovative Manufacturing in Food and the National Centre for Food Manufacturing were highlighted as the most important partners/partnerships within the ME. Outside the ME, links with a variety of partners were highlighted, including: FERA, Norwich Research Park and Innovate UK. Internationally, links with the WHO and universities, such as the Hellenic Open University, Greece, were identified.

Energy and low carbon technologies

The Energy Research Accelerator and Energy Systems Catapult were identified by multiple respondents as being among the most important partners/partnerships in the ME. University partners, such as Aston, Birmingham, Nottingham and Warwick, were also recognised whilst key industrial partners included Jaguar Land Rover and Siemens.

Outside the ME, key partners and partnerships cited included universities elsewhere in the UK (e.g. Manchester and Oxford Brookes) and internationally, as well as national bodies such as Innovate UK. The SUPERGEN Bioenergy Hub which brings together industry, academia and other stakeholders was also cited by multiple respondents.

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Healthcare, life sciences and translational medicine

In addition to universities (Birmingham, Leicester, Nottingham), the Academic Health Science Networks and Medilinks across both East and West Midlands, were cited as key partners. Outside the ME, universities such as Manchester and Oxford, and commercial players such as Alcon and GlaxoSmithKline were also identified as key partners.

Creative, digital and design sector

Again, a variety of different partners and networks within the ME were highlighted. These included some networks (Birmingham Science City Alliance, Venturefest East Midlands, and Worcestershire Innovation) and a host of university partners (De Montfort, Leicester, Loughborough, Nottingham, and Nottingham Trent).

Outside the ME, respondents identified links with national (UCL, Cambridge) and international (Sydney, Tsinghua (China)) universities, UK projects (Alliance Project on textiles), and UK networks and centres (Creative Industries Federation, Arts Council England, National Cyber Security Centre, UK Fashion and Textiles).

Transport technologies

Key partners within the ME were very similar to the key assets discussed above. They included large corporates (Jaguar Land Rover, Rolls-RoyceRolls-Royce), research organisations (HORIBA MIRA) individual universities (Birmingham, Nottingham, Warwick, etc.), and facilities/networks (Warwick Manufacturing Group, Catapults, Manufacturing Technology Centre).

Key partners identified outside the ME geography tended to be universities located elsewhere in the UK, including Bristol, Cambridge, Imperial and Oxford.

Partners in the Midlands Engine

The Table below lists all 150 organisations (whether HEI, RTO, LEP, business, etc.) also based in the Midlands Engine that survey respondents identified having links with.

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Partners identified by e-consultation respondents

Advanced Propulsion Centre Evoque-e National Cyber Skills Centre

Aerospace Technology Institute Faering Ltd National Grid

Aircraft Research Association Ltd GBSLEP National Grid Warwick

APC Power Electronics Spoke Greater Lincolnshire LEP Nottingham Trent University

Aston University GRiST: Aston and Warwick with NHS Trusts Nottingham University

Aston Vision Sciences Harper Adams University Nottinghamshire Healthcare NHS Foundation Trust

Aylesbury Vale District Council Health and Safety Laboratory Optimec

BBR Optometry Ltd High Performance Technology Forum Precision Medicine Institute

BGS Highways Agency QinetiQ Ltd

BioCity Group HMV Rolls-RoyceRolls-Royce

Birmingham Children’s Hospital HORIBA MIRA Royal Centre for Defence Medicine

Birmingham City Council Green Commission IAT Saffron Labinal Power Systems

Birmingham City University IMPART Serendipity incubator (Aston Science park)

Birmingham Health Partners IMPETUS Siemens Wind Power R&D at Keele Science Park

Birmingham Hospitals iNET Silverstone Park Cluster

Birmingham Science City Alliance Ingenuity Network Skylon Innovation Network

Black Country LEP Institute of Aerospace Technology, University of SNC-Lavalin Nottingham

British Gas Invest in Nottingham Solihull MBC

British Geological Survey Jaguar Land Rover Space Centre

Campden BRI JCB Sterling GEO

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Caterpillar Innovation and Research Centre JLR Sustainability West Midlands

CCAV Innovate UK projects Keele University The ICO-CDT

Cenex KTN foods The Open University

Centre for Sustainable Energy Use in Food Laing O'Rourke Transport for West Midlands

Centre of Innovative Manufacturing - Food Leicester City Council Transport Systems Catapult

City of Wolverhampton Council Leicester Textiles Partnership TRIIFIC

Coventry and Warwickshire LEP Leicestershire Low Carbon Sector Growth Panel UK Science Park Alliance

Coventry University Leicestershire Textiles Hub UK Space Agency

Cranfield University Life Science Opportunity Zone at Charnwood Campus UKTI EM

Creative Industries Sector Group (De Montfort LLEP UNIP Management Limited University)

Cuttlefish Loughborough University Unipart

De Montfort University MAHLE Powertrain Ltd University Alliance (midlands Unis)

De Montfort University’s Institute of Energy and Malvern Cyber Security Cluster University Hospitals Birmingham NHSFT Sustainable Development (IESD)

Derby Chamber of Commerce Manufacturing Technology Centre University Hospitals of Leicester

Derby City Council Marches Energy Agency University of Birmingham

Derby Teaching Hospitals NHS Foundation Trust Medilink East Midlands University of Buckingham

Design Star Microcab University of Derby

Digital Birmingham Midlands Engine Financial Instruments Group University of Derby

DNRC - multiple stakeholders Midland Eye University of Leicester

DTA Energy initiative Midlands 3 Cities doctoral training partnership University of Leicester

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East Midlands Academic Health Science Network Midlands Aerospace Alliance University of Lincoln - Institute for AgriFood Technology

EM Airport Midlands and Lancashire Commissioning Support Unit University of Nottingham

EMBRACE Midlands Combined Universities Enterprise Group University of Nottingham

Enabling Innovation Midlands Connect University of Wolverhampton

Encraft Midlands Enterprise Venturefest East Midlands

Energy Research Accelerator Midlands Innovation Warwick Manufacturing Group

Energy Systems Catapult MK: Smart West Midlands Academic Health Science Network

Energy Technologies Institute Mondelez International Ltd West Midlands Combined Authority

ENGAGE (Nottingham) & the Space Science Catapult MOOG Westcott Space Enterprise Zone

Enterprise at Nottingham MTC Worcestershire Innovation Programme (WINN)

Enterprise Educators UK (EEUK) National Centre for Food Manufacturing Source: SQW analysis of e-consultation responses

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International partners

The table below lists all those international organisations (whether HEI, business, etc.) that survey respondents identified having links with.

International partners identified through the e-consultation

Alliance Textiles, USA Hydrogenics, Canada

AmpliPhi Biosciences, USA IBSL SpA, Italy

Boeing, USA Indian Nuclear Power, India

Electric Power Research Institute, USA International Energy Agency (IEA)

EP Tender, France Japan Atomic Energy Agency, Japan

ERRIN, Belgium JRC in Europe

EU Clean Sky JTI Mistra Future Fashion, Sweden

EU Horizon 2020 Mitsubishi, Japan

Euratom Novosibirsk State University, Russia

European Energy Research Alliance (EERA) ORBIT - EU network of construction technology players

Network On Quality By Design And Process Analytical TERI University, India Technology Sciences, Europe

European Space Agency (ESA) The European Union

Ford, USA Torino Piemonte Aerospace cluster, Italy

Fraunhofer UMSICHT, Germany Tsinghua University, China

Grey Systems and its Applications (GSIA) International Research UCB, Belgium Network

Guangdong University of Technology, China University of Technology, Australia

Hellenic Open University, Greece World Health Organisation, Switzerland Source: SQW analysis of e-consultation responses

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Annex J: Driving competitiveness through our Enabling Competencies

J.1 This Annex provides a number of examples where our enabling capabilities align with and drive competitiveness throughout the four identified Market Driven Priorities.

Next Generation Transport

Driving competitiveness through our Enabling Competencies

iTRAQ Advanced Manufacturing & Engineering University of Leicester and De Digital Technologies Montford University Systems Integration

iTRAQ (iTRAQ: Integrated Traffic Management and Air Quality Control using downstream Space Services) is a dynamic and adaptive traffic management system designed to optimize both traffic flow and air pollution in urban environments. The system responds to real-time traffic flow and air quality data from in situ and space based sensors to forecast enhanced traffic management strategies. Local authorities have to meet the challenges of sustainable transport whilst complying with conflicting air quality targets. Universities, industry and local authorities in the East Midlands collaborated in a feasibility study, funded by the European Space Agency, to demonstrate the use of computer intelligence and space data in a new approach to real time traffic and air quality management. Simulation test results confirm the feasibility of this integrated system, consistently demonstrating reductions in traffic delay while increasing traffic flow and optimising local air quality.

Driving competitiveness through our Enabling Competencies

EVOQUE_E RESEARCH Advanced Manufacturing & Engineering PROJECT Digital Technologies Jaguar Land Rover Systems Integration

The project has brought together leading engineers and technologists from academia, the supply chain and industry to create a number of unique and innovative solutions focused on the design and development of innovative hybrid and electric propulsion systems, integrated structures, power electronics, electric drives and energy optimisation. The project has delivered a technology platform which is scaleable, configurable and compatible in the form of three technology vehicle demonstrators: Mild Hybrid Electric Vehicle, Plug-in Hybrid Electric Vehicle, and Battery Electric Vehicle. Partners include Cranfield University, Bristol University, Newcastle University, Tata Steel, Motor Design Ltd, AVL Powertrain UK Ltd, Delta Motorsport, Zytek Automotive, GKN Driveline, AVL, Drive System Design, Williams, with funding provided by Innovate UK.

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Future Food Processing

Driving competitiveness through our Enabling Competencies

THE NEXT GENERATION OF Advanced Manufacturing & Engineering FOOD MACHINERY Digital Technologies Manufacturing Technology Centre Systems Integration

The MTC worked closely with Wymbs Engineering Limited, based outside of the Midlands Engine in Cheshire to develop a highly improved depositing system for leading food manufacturers in the UK and overseas. Wymbs manufactures bespoke machinery for the confectionery, bakery and dairy industries, enabling products to be deposited into moulded impressions, onto biscuits or directly onto travelling conveyors and steel oven bands. The difficulty in depositing many food products lies in their complex structures, which change during production. With support from Innovate UK funding, MTC engineers used new ways to model the flow of product through the depositing system, enabling improvements to established designs to be trialled on a computer, before committing to a physical prototype. The MTC’s expertise led to an improvement in the flow of the product and the enhancement of the overall system speed. These were verified by on-site trials, both at Wymbs and with an end user.22 The MTC’s work with Wymbs set out above flowed from an earlier ERDF funded project: CASim (computer aided simulation), a joint project with University of Birmingham that enabled MTC to develop its computer modelling and simulation capability: the example provides evidence of the translation of basic research through the TRL continuum to the launch of a new product.

Medical Technologies and Pharmaceuticals

Driving competitiveness through our Enabling Competencies

EPSRC Centre for Innovative Advanced Manufacturing & Engineering Manufacturing in Regenerative Digital Technologies Medicine

Loughborough University Systems Integration

Research at Loughborough University generated innovative methods of automatically and consistently culturing human stem cells. These are key to regenerative therapies for a range of conditions, such as strokes, neurodegenerative diseases, cancer and heart disease. Whilst contributing to patient health and quality of life, regenerative medicine is also creating a new industry sector. With long-term investment from EPSRC, BBSRC, MRC and Innovate UK, the research has led to the development of the CompacT SelecTTM automated cell culture system launched by TAP Biosystems, a leading supplier of innovative cell culture and fermentation systems for life science. By 2014, 47 of the systems worth over £20 million had been sold, 40% in Europe and 60% in the USA. More recently, leading stem cell therapy company ReNeuron announced it would be using the system as part of its production process for clinical and commercial stem cell therapies at a new Advanced Therapy Medicinal Products (ATMP) manufacturing facility in Wales. Loughborough continues to deliver cell culture process development services to ReNeuron and others via the university’s consultancy arm.

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Energy and Low Carbon

Driving competitiveness through our Enabling Competencies

Developing "The GenGame" Advanced Manufacturing & Engineering domestic smart grid platform Digital Technologies Oswald Consultancy Ltd, Serious Games Institute & others Systems Integration

This three-year project funded by Innovate UK is led by Oswald Consultancy Ltd, a Warwickshire based engineering firm providing services in the areas of energy and heat, working alongside the Serious Games Institute at Coventry University, Leicestershire-based Jaamacoe Solutions and partners outside the region. The project is based around the challenges faced by the UK in meeting its carbon reduction targets in the context of the electrification of heat and transport. One possible solution to this is to utilise the flexibility that customers have in how they use electricity. The project is exploring the long term opportunity for domestic householders to trade appliance load curtailments via an online ‘serious game’. The project will trial gaming options with 2,000 customers to test ease of recruitment, the size of load response available and whether this can be reliably sustained to be of use to distribution network operators and other potential users of demand-side reduction services.

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Annex K: Innovation networks and behaviours

K.1 Across our 11 LEPs there are numerous alliances, associations and collaborator networks, crucial to supporting innovation activity within the region. This Annex provides further examples of collaborations across the Midlands Engine, and international collaborations that Midlands Engine universities are part of. The first table provides an insight into the nature of innovation collaboration across the region, and the second table provides four examples of international collaborations and partnerships to illustrate the breadth of our collaboration.

Table K-1: Examples of collaborations and innovation Energy Research Accelerator MediCity

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The Energy Research Accelerator is partnership is made up of six internationally-renowned MediCity is a collaboration between Boots and BioCity in Nottingham. BioCity Nottingham was Midlands universities (Aston, Birmingham, Nottingham, Leicester, Loughborough, Warwick) launched in 2012 as one of the first bioscience incubators in Europe, and the BioCity group and the British Geological Survey. ERA works in close collaboration with industrial partners in now has additional sites in Scotland and at Alderley Park, Cheshire. manufacturing, transport, engineering and science. ERA is focused around three core themes, MediCity is a collaboration with Boots, which is designed as an incubator for innovative start- selected in terms of their research and economic potential: Geo-Energy Systems Accelerator ups and established companies in the consumer healthcare, medical technologies, diagnostics (G-ERA), focusing on next generation gaseous related technologies including geo-energy and and beauty products sectors. Tenants benefit from Boots’ expertise in the global healthcare energy storage to help to decarbonise the energy generation and transport sectors; Integrated sector, including access to innovation and product development knowledge. In addition, tenants Energy Systems Accelerator (I-ERA), delivering integrated energy solutions addressing energy are linked into BioCity’s wider network of innovative firms. intensive sectors such as transport and buildings through manufacturing; and Thermal Energy Accelerator (T-ERA), leading the development and integration hot and cold energy Bringing together scientific and business expertise, the Expert Network connects BioCity pre- technologies, delivering domestic and grid-scale applications and innovative solutions to heat start-up and established companies to the wider industry, creating a UK wide innovation homes and buildings. ERA’s energy research funding portfolio is £71.7m (EPSRC).23 community. Harnessing the talent and regional heritage, providing insights, mentoring and a ‘critical friend’ to young companies as they move through the business development pipeline.24

The Food and Drink Forum MK:Smart

Since its establishment in 1998, The Food and Drink Forum Ltd has built a strong reputation for MK:Smart is a large collaborative initiative developing innovative solutions to support economic supporting and developing successful food enterprises as well as representing the industry at a growth in Milton Keynes. It is led by the Open University and is part funded by HEFCE (the local, regional and national level. Higher Education Funding Council for England). Other local partners include Milton Keynes The Forum, which is based in the East Midlands, is led by an industry Board sourced from Council, Community Action:MK, the Transport Systems Catapult, and the University of regional businesses, academic institutions and other key bodies involved in food and drink Bedfordshire’s Milton Keynes Campus. The Future Cities Catapult and the University of manufacturing and its supply-chains. Cambridge are among the initiative’s wider partners. The Forum’s membership is open to firms throughout the food supply chain, from primary The state-of-the-art ‘MK Data Hub’ supports the acquisition of significant amounts of data on producers to retailers and distributors, but the majority of members are SME processors and energy and water consumption, transport flows, economic indicators, and crowdsourced data manufacturers. from social media. Analysis of this allows innovative responses to transport, energy and water management issues. Businesses can use the Forum to access a wide range of support services including events, networking opportunities and regular updates on the development of the sector. MK:Smart also runs education, business and community engagement events such as a smart city education programme and an integrated programme of business engagement, to support businesses wanting to take advantage of the innovation capabilities developed in MK:Smart.25

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Table K-2: Examples of university collaboration University of Warwick University of Nottingham The University of Warwick has been working with Monash University in Melbourne, Australia The University of Nottingham is a founding member of Universitas 21 – a global network of 25 since 2009 and together they launched the Monash Warwick Alliance in 2012. This aims to research-intensive universities. It is also a partner in STEP, the EU-funded Marie Curie Initial undertake research on globally relevant problems and produce graduates with a global Training Network which aims to develop the next generation of researchers in the field of education. The partnership includes the China, India, Malaysia and South Africa campuses of energy beam processing. The collaboration also involves experimental and theoretical work Monash University, and the two Universities’ sites in Italy (Warwick has had a base in Venice with colleagues in Belgium, France, Germany, Spain and Switzerland. for more than 40 years). Nottingham has campuses in China and Malaysia. Collaborations in China include work with Warwick is a partner in the Centre for Urban Science and Progress CUSP), based at New the Ningbo city government to develop the International Academy for Marine Economy and York University, one of America’s leading higher education institutions. CUSP is an applied Technology, whilst the Malaysia campus hosts the Crops for the Future Research Centre which science research institute which aims to address the needs of cities worldwide and educate the was established with support from the Malaysian government. next generation of engineers in how to apply that research. Other partners include The City Current collaborations include work with Ulm University (Germany) on electron microscopes; University of New York, Carnegie Mellon University (both USA), University of Toronto (Canada) Universidad Autonoma de Yucatan (Mexico), GFZ Potsdam (Germany), UCL and the British and the Indian Institute of Technology (Mumbai, India). Geological Society to understand impact of climate change on the collapse of the Maya; Warwick is also a partner in CARTA (Consortium for Advanced Research Training in Africa), an Brazilian Council of State Funding Agencies (CONFAP) and Sao Paolo researchers on initiative of 13 African universities and research institutes and 8 northern partners that aims to inflammatory diseases; and Ain Shams and Alexandria University (Egypt) on the 3D digitisation develop and deliver an innovative model for doctoral training in sub-Saharan Africa and to and visualisation of ancient artefacts. strengthen the capacity of institutions to conduct and lead internationally-competitive research.

Aston University Loughborough University

Aston University has four international strategic networks: Aston in India (including a Loughborough University has international links covering academic research as well as joint collaboration with the Indian Institute of Technology in Ropar); Aston in China and Hong educational programmes. For example, Loughborough has strong links with the Kong (partners include Beijing University of Technology, Chinese University of Hong Kong, Massachusetts Institute of Technology (MIT, USA), one of the world’s leading universities, and Shanghai Jiatong University); Erasmus+ Project: Harmony which aims to aims to particularly in particularly in the areas of Engineering and Sport as well as being a partner in contribute to the development of comprehensive internationalization strategies (17 partners the MIT Regional Entrepreneur Accelerator Programme. across the EU and Armenia, Belarus and Russia); and the Erasmus Munuds Project: Unique The Institute for Sports Research is a Singapore-based international collaboration between which aims to support international collaboration and exchange (9 partners across the EU and Nanyang Technological University (NTU, Singapore) and Loughborough, which was created in China, India, Mexico, Namibia and Russia). 2011. A more longstanding link are the engineering collaborations with the Indian Institute of In addition, Aston has further partnerships covering research collaborations, teaching and Technology Delhi which have been running since the 1970s. Loughborough is also a member exchange. Partners include University of Stellenbosch (South Africa), Queensland University of of the UNITECH International academic network – an association of eight European Technology (Australia), University of Florida (USA), University of Sao Paulo (Brazil), engineering universities which aims to prepare top engineering students for the global business Universidad De Sevilla (Spain) and University of Seoul (Korea). challenges of tomorrow.

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1 http://www.op.mahidol.ac.th/orra/SciVal/SciVal_USER_GUIDE.pdf 2 https://www.gov.uk/government/publications/bioscience-and-health-technology-database-annual-report-2015 3 Fast Track to the Future - A strategy for productivity and growth in the UK rail supply chain 4 ibid 5 https://issuu.com/nuclear_industry_association/docs/nia_jobs_map_2016 6 https://dl.dropboxusercontent.com/u/143152432/E-Smart/REA%20Review%202016%20Annual%20Report/index.html#72 7 https://dl.dropboxusercontent.com/u/143152432/E-Smart/REA%20Review%202016%20Annual%20Report/index.html#72 8 https://www.scottish-enterprise.com/knowledge%20hub/articles/guide/renewables%20support%20for%20scottish%20companies 9 https://www.iaea.org/PRIS/WorldStatistics/NuclearShareofElectricityGeneration.aspx 10 World Energy Outlook, 2014. 11 World Energy Outlook, 2014. 12 http://www.r-e-a.net/upload/rea_uk_energy_storage_report_november_2015_-_final.pdf 13 http://www.businessgreen.com/bg/opinion/2424086/can-the-uk-be-a-global-leader-in-energy-storage-not-without-a-clear-government-strategy 14 2016 Utilities Industries Trends, PWC, 2016 15 Global Energy Storage Market Overview & Regional Summary Report 2015, Energy Storage Council, 2015 16 Global Energy Storage Market Overview & Regional Summary Report 2015, Energy Storage Council, 2015 17 Renewables 2015: global status report. 18 Renewable Energy: Medium-Term Market Report 2015, IEA, 2015. 19 http://www.ft.com/cms/s/0/123f1af0-d97e-11e5-a72f-1e7744c66818.html?siteedition=uk#axzz4LjpzwwYZ 20 The European offshore wind industry - key trends and statistics 2014, European Wind Energy Association, 2015. 21 Figures do not sum as some organisations responded to multiple Themes 22 Based on http://www.the-mtc.org/our-case-studies/the-mtc-helps-sme-develop-the-next-generation-of-food-machinery 23 http://www.era.ac.uk/ 24 http://www.biocity.co.uk/medicity/nottingham 25 http://www.mksmart.org/about/

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