Rabbit Anti-HRC/FITC Conjugated Antibody

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Rabbit Anti-HRC/FITC Conjugated antibody

SL17387R-FITC

Product Name: Anti-HRC/FITC Chinese Name: FITC标记的HRC蛋白抗体 HCP; HRC; HRC histidine rich calcium binding protein; MGC133236; Sarcoplasmic Alias: reticulum histidine-rich calcium-binding protein; SRCH_HUMAN. Organism Species: Rabbit Clonality: Polyclonal React Species: Human, ICC=1:50-200IF=1:50-200 Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 77kDa Form: Lyophilized or Liquid Concentration: 1mg/ml immunogen: KLH conjugated synthetic peptide derived from human HRC Lsotype: IgG Purification: affinity purified by Protein A Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storewww.sunlongbiotech.com at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. background: HRC is a 699 amino acid that binds low-density lipoprotein with high affinity. As a high capacity calcium binding protein, HRC regulates the sequestration and release of calcium in the lumen of the junctional sarcoplasmic reticulum (SR) of cardiac, skeletal Product Detail: and smooth muscle. This mechanism may involve direct interaction between HRC and the cytoplasmic domain of Triadin, an integral membrane protein of the SR. The gene encoding HRC maps to human chromosome 19q13.33 and mouse chromosome 7 B4

Function: May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle.

Subcellular Location: Sarcoplasmic reticulum lumen.

Similarity: To rabbit HRC.

Database links:

Entrez Gene: 3270 Human

Omim: 142705 Human

SwissProt: P23327 Human

Unigene: 436885 Human

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.